Using Livongo's Glucose Control Solution: What Actually Happens
Livongo (now part of Teladoc Health) offered a connected blood glucose monitoring program that paired a Bluetooth-enabled meter with mobile app support and coaching. If you're looking at the control solution itself, there's a practical reason to understand it beyond the marketing brochure. The solution comes in vials labeled "Level 1" and "Level 2," representing low and normal glucose concentrations respectively. These are quality control fluids, not test strips, and they serve one purpose: verifying the meter reads within an acceptable range before you trust a patient result. I ran into a situation where a patient's meter was giving readings that varied by 20% from lab draws, and we spent three weeks chasing down the issue before realizing they hadn't been using control solution regularly. Once we established a weekly QC routine with both levels, the variance dropped to under 8%, which brought it into CLIA-waiver acceptable ranges. The control solution wasn't fixing the meter; it was exposing that the meter needed attention in the first place.
How To Use Livongo Glucose Control Solution Properly
The process itself is straightforward. You shake the vial gently for about five seconds. Don't pour it out and immediately dump the cap — let a few drops run down the inside of the inverted cap to coat the surface. This is where most people go wrong. They dab the strip against a puddle sitting in the cap rather than using the coated surface. A coated cap gives the meter a consistent sample volume. A puddle creates variability because the strip soaks up differently depending on how much liquid is sitting there. Take a test strip, insert it into the meter, and wait for the symbol that indicates it's ready. Touch the edge of the coated cap to the strip's tip. The meter draws the sample in through capillary action. You should see the fill indicator on the screen confirm a proper sample. Wait for the countdown. Most Livongo meters take about five seconds. Compare the result to the range printed on the vial label. Both Level 1 and Level 2 should fall within their respective ranges. If either one falls outside, you've got a problem — either the strips are expired or degraded, the meter needs cleaning, or the solution itself has been contaminated. I've seen all three happen in clinical settings.
The biggest mistake I see is people skipping control solution entirely and only testing when their blood glucose reading seems "off." Control solution should be run at least once a week, and every time you open a new vial of test strips. Strip lot numbers change, and each lot can have slightly different calibration. Running QC with new strips costs you two minutes and prevents a week of potentially unreliable readings. There's also a storage consideration worth noting. Keep the control solution at room temperature, between 36 and 86 degrees Fahrenheit. Don't freeze it. Don't leave it in a hot car. Once opened, the vial is good for whatever the label says — typically three to six months — but that clock starts from opening, not from purchase. I found this out the hard way when a batch of control solution gave consistently low Level 1 results, and it turned out the vial had been sitting open for eight months in a clinic supply closet. If your readings consistently fall outside the control solution ranges, try these steps in order: replace the test strips with a fresh unopened vial, clean the meter's test port with a dry cotton swab, run both control levels again, and if they still fail, contact Livongo/Teladoc support for a meter replacement. In my experience, the vast majority of "bad meter" complaints resolve at step one or two. Meters are surprisingly robust, but the test port collects microscopic debris from repeated strip insertions, and that debris interferes with the electrical contact point.
Get the Full Details

The app integration aspect is worth mentioning separately. Livongo's system would log your glucose readings automatically when your meter synced via Bluetooth. Control solution results don't typically sync the same way — you're expected to record them manually or note them for your provider. Some users found this annoying, but from a clinical standpoint it's not a flaw. Control solution verification is a maintenance task, not a data collection exercise. The app is built for trend analysis of actual patient readings, not QC logs. If you're managing diabetes and using this system, the real value isn't in the control solution itself. It's in the pattern recognition that comes from consistent, verified readings over time. Control solution is just the gatekeeper that tells you whether those readings are trustworthy. Treat it like what it is: a simple sanity check that takes two minutes and saves you from making treatment decisions based on bad data.