Using an Oxygen Concentrator with Puppywarmer Systems
I have spent more years than I care to count working with small animal resuscitation equipment, specifically the Puppywarmer setup paired with oxygen concentrators. Most people buy these without reading the manual first. You should. The Puppywarmer is essentially a specialized incubator for neonatal animals — puppies, kittens, sometimes exotics. The oxygen concentrator adds therapeutic O2 when those neonates are having trouble breathing or recovering from complications. Putting the two together works fine once you figure out the workflow. The concentrator delivers 90-95% oxygen at flows typically rated 1-10 liters per minute. You will want to stay within that range unless your animal is under direct veterinary supervision.
Puppywarmer Oxygen Concentrator Instructions
Here is how I actually set this up in practice, not how the marketing materials suggest. First, place the concentrator on a stable surface near the Puppywarmer but not inside the unit. These things pull air from the room and compress it. They need clearance — at least 6 inches on all sides. I once watched a tech try to squeeze the unit between the Puppywarmer and a wall, and within twenty minutes the inlet filter was clogged with dust because airflow was starved. The unit didn't shut off. It just started pumping lower-quality oxygen. Nobody noticed until the O2 readout dropped to 82%. Took another ten minutes to realize what was happening. Connect the oxygen tubing from the concentrator outlet to the Puppywarmer's O2 inlet port. There is usually a standard 22mm fitting. If you are using an adapter, make sure it seals tight. A loose connection here means your oxygen is venting into the room instead of going into the chamber. You can check for this by feeling the joint while the system is running, or by watching the oxygen concentration monitor on the Puppywarmer. It should climb within 1-2 minutes of turning the concentrator on. If it stays low, you have a leak somewhere.
Set the flow rate based on what your veterinarian has recommended. For most neonatal resuscitation cases, we run between 1-3 L/min. Higher flows can dry out the animals' airways and actually make breathing harder. I know that sounds counterintuitive. More oxygen does not always mean better. At some point you are just blowing dry gas over delicate tissue and irritating it. Keep humidity in mind too. Some setups include an oxygen humidifier bottle — use one if you are running above 3 L/min for more than twenty minutes. The Puppywarmer itself has an O2 sensor and display. Watch that number. It tells you what concentration is actually inside the chamber. The concentrator's dial is a flow setting, not a concentration setting. Those are two different things. People mix them up constantly. Your concentrator might be set to 5 L/min but if the chamber is leaking or the door isn't sealed, the O2 percentage inside will never reach what you expect. I also want to mention the noise factor. These concentrators run a compressor. They make sound — roughly 50-60 decibels at close range. Neonatal animals are sensitive to vibration and noise. If you are working with premature pups, you may want to place the concentrator in the next room and route the tubing in. It works, but you lose some responsiveness when adjusting flow. I keep mine in the same room but position it so the exhaust fan is facing away from the incubator. The warm air from the exhaust can affect the Puppywarmer's temperature readings if it blows directly on the unit.
Get the Full Details

A few things this system does poorly. It cannot replace a ventilator. If an animal is not breathing adequately on supplemental oxygen alone, you need mechanical support. The Puppywarmer with a concentrator is for mild to moderate respiratory support, not for apnea or severe distress. Also, the concentrator needs routine filter maintenance. The inlet filter should be checked weekly and washed or replaced monthly depending on your environment. I have seen units go six months without a filter change in busy clinics. The oxygen purity degrades gradually — you won't notice it day to day, but over time the output drops below therapeutic levels. Test your concentrator periodically with an O2 analyzer if you can. A $200 handheld analyzer will save you from relying on assumptions. Power is another consideration. Concentrators draw significant current — roughly 2-4 amps during normal operation, with spikes when the compressor cycles on. Do not run this off a weak extension cord or a daisy-chained power strip. Use a dedicated outlet. A voltage drop here can cause the compressor to struggle and shorten the unit's lifespan significantly. If you are looking for the official documentation, Puppywarmer provides instructions through their website and included packaging. Search for "Puppywarmer Oxygen Concentrator Instructions" and you will find the manufacturer PDF. But honestly, the manual covers the basics. The real knowledge comes from using the equipment and learning where it breaks down in practice.
One more thing that trips people up: the oxygen concentrator should always be turned off before you disconnect tubing. Not a big deal in most cases, but if you yank the connection while the compressor is pressurized, you can damage the fittings or lose the seal. It takes two seconds to flip the switch. Don't skip it. For anything beyond basic oxygen supplementation — prolonged critical cases, post-surgical monitoring, animals with congenital respiratory issues — work closely with a veterinarian. This equipment is a tool, not a treatment plan. It does not diagnose. It does not adjust itself. It sits there and gives you oxygen at whatever flow you set it to. Your judgment determines whether that is the right call.