Advertisement
| chemical engineering product development: Chemical Product Design E. L. Cussler, G. D. Moggridge, 2011-05-12 The chemical industry is changing, going beyond commodity chemicals to a palette of higher value added products. This groundbreaking book, now revised and expanded, documents this change and shows how to meet the challenges implied. Presenting a four-step design process - needs, ideas, selection, manufacture - the authors supply readers with a simple design template that can be applied to a wide variety of products. Four new chapters on commodities, devices, molecules/drugs and microstructures show how this template can be applied to products including oxygen for emphysema patients, pharmaceuticals like taxol, dietary supplements like lutein, and beverages which are more satisfying. For different groups of products the authors supply both strategies for design and summaries of relevant science. Economic analysis is expanded, emphasizing the importance of speed-to-market, selling ideas to investors and an expectation of limited time in the market. Extra examples, homework problems and a solutions manual are available. |
| chemical engineering product development: Chemical Product Design: Towards a Perspective through Case Studies Ka M. Ng, Rafiqul Gani, Kim Dam-Johansen, 2006-10-24 Chemical Product Design: Towards a Perspective through Case Studies provides a framework for chemical product design problems which are clearly defined together with different solution approaches. This book covers the latest methods and tools currently available in the field and discusses future challenges that the chemical industry is faced with. It focuses on important issues of chemical product design and provides a good overview on industrial chemical product design problems through case studies supplied by leading experts. The editors of Chemical Product Design teach chemical product design at graduate level courses and also serve as consultants for various chemical companies. They have also developed experimental techniques for chemical product design as well as computer-aided design methods and tools. - Highlights important issues of chemical product design through case studies - Case studies supplied by leading experts in chemical product design - Provides a complete framework for chemical product design |
| chemical engineering product development: Chemical Product Design E. L. Cussler, G. D. Moggridge, 2001-04-16 Until recently, the chemical industry has been dominated by the manufacture of bulk commodity chemicals such as benzene, ammonia, and polypropylene. However, over the last decade a significant shift occurred. Now most chemical companies devote any new resources to the design and manufacture of specialty, high value-added chemical products such as pharmaceuticals, cosmetics, and electronic coatings. Although the jobs held by chemical engineers have also changed to reflect this altered business, their training has remained static, emphasizing traditional commodities. This ground-breaking text starts to redress the balance between commodities and higher value-added products. It expands the scope of chemical engineering design to encompass both process design and product design. The authors use a four-step procedure for chemical product design - needs, ideas, selection, manufacture - drawing numerous examples from industry to illustrate the discussion. The book concludes with a brief review of the economic issues. Chemical engineering students and beginning chemical engineers will find this text an inviting introduction to chemical product design. |
| chemical engineering product development: Chemical Engineering in the Pharmaceutical Industry Mary T. am Ende, David J. am Ende, 2019-04-08 A guide to the important chemical engineering concepts for the development of new drugs, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry offers a guide to the experimental and computational methods related to drug product design and development. The second edition has been greatly expanded and covers a range of topics related to formulation design and process development of drug products. The authors review basic analytics for quantitation of drug product quality attributes, such as potency, purity, content uniformity, and dissolution, that are addressed with consideration of the applied statistics, process analytical technology, and process control. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The contributors explore technology transfer and scale-up of batch processes that are exemplified experimentally and computationally. Written for engineers working in the field, the book examines in-silico process modeling tools that streamline experimental screening approaches. In addition, the authors discuss the emerging field of continuous drug product manufacturing. This revised second edition: Contains 21 new or revised chapters, including chapters on quality by design, computational approaches for drug product modeling, process design with PAT and process control, engineering challenges and solutions Covers chemistry and engineering activities related to dosage form design, and process development, and scale-up Offers analytical methods and applied statistics that highlight drug product quality attributes as design features Presents updated and new example calculations and associated solutions Includes contributions from leading experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduation students, and professionals in the field of pharmaceutical sciences and manufacturing, Chemical Engineering in the Pharmaceutical Industry, Second Edition contains information designed to be of use from the engineer's perspective and spans information from solid to semi-solid to lyophilized drug products. |
| chemical engineering product development: Chemical Engineering in the Pharmaceutical Industry David J. am Ende, Mary T. am Ende, 2019-04-23 A guide to the development and manufacturing of pharmaceutical products written for professionals in the industry, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry is a practical book that highlights chemistry and chemical engineering. The book’s regulatory quality strategies target the development and manufacturing of pharmaceutically active ingredients of pharmaceutical products. The expanded second edition contains revised content with many new case studies and additional example calculations that are of interest to chemical engineers. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The active pharmaceutical ingredients book puts the focus on the chemistry, chemical engineering, and unit operations specific to development and manufacturing of the active ingredients of the pharmaceutical product. The drug substance operations section includes information on chemical reactions, mixing, distillations, extractions, crystallizations, filtration, drying, and wet and dry milling. In addition, the book includes many applications of process modeling and modern software tools that are geared toward batch-scale and continuous drug substance pharmaceutical operations. This updated second edition: Contains 30new chapters or revised chapters specific to API, covering topics including: manufacturing quality by design, computational approaches, continuous manufacturing, crystallization and final form, process safety Expanded topics of scale-up, continuous processing, applications of thermodynamics and thermodynamic modeling, filtration and drying Presents updated and expanded example calculations Includes contributions from noted experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduate students, and professionals in the field of pharmaceutical sciences and manufacturing, the second edition of Chemical Engineering in the Pharmaceutical Industryf ocuses on the development and chemical engineering as well as operations specific to the design, formulation, and manufacture of drug substance and products. |
| chemical engineering product development: Sustainable Development in Chemical Engineering Vincenzo Piemonte, Marcello De Falco, Angelo Basile, 2013-05-28 Sustainable development is an area that has world-wide appeal, from developed industrialized countries to the developing world. Development of innovative technologies to achieve sustainability is being addressed by many European countries, the USA and also China and India. The need for chemical processes to be safe, compact, flexible, energy efficient, and environmentally benign and conducive to the rapid commercialization of new products poses new challenges for chemical engineers. This book examines the newest technologies for sustainable development in chemical engineering, through careful analysis of the technical aspects, and discussion of the possible fields of industrial development. The book is broad in its coverage, and is divided into four sections: Energy Production, covering renewable energies, innovative solar technologies, cogeneration plants, and smart grids Process Intensification, describing why it is important in the chemical and petrochemical industry, the engineering approach, and nanoparticles as a smart technology for bioremediation Bio-based Platform Chemicals, including the production of bioethanol and biodiesel, bioplastics production and biodegradability, and biosurfactants Soil and Water Remediation, covering water management and re-use, and soil remediation technologies Throughout the book there are case studies and examples of industrial processes in practice. |
| chemical engineering product development: Design & Development of Biological, Chemical, Food and Pharmaceutical Products Johannes A. Wesselingh, Soren Kiil, Martin E. Vigild, 2007-09-27 Design and Development of Biological, Chemical, Food and Pharmaceutical Products has been developed from course material from the authors’ course in Chemical and Biochemical Product Design which has been running at the Technical University Denmark for years. The book draws on the authors’ years of experience in academia and industry to provide an accessible introduction to this field, approaching product development as a subject in its own right rather than a sideline of process engineering In this subject area, practical experience is the key to learning and this textbook provides examples and techniques to help the student get the best out of their projects. Design and Development of Biological, Chemical, Food and Pharma Products aims to aid students in developing good working habits for product development. Students are challenged with examples of real problems that they might encounter as engineers. Written in an informal, student-friendly tone, this unique book includes examples of real products and experiences from real companies to bring the subject alive for the student as well as placing emphasis on problem solving and team learning to set a foundation for a future in industry. The book includes an introduction to the subject of Colloid Science, which is important in product development, but neglected in many curricula. Knowledge of engineering calculus and basic physical chemistry as well as basic inorganic and organic chemistry are assumed. An invaluable text for students of product design in chemical engineering, biochemistry, biotechnology, pharmaceutical sciences and product development. Uses many examples and case studies drawn from a range of industries. Approaches product development as a subject in its own right rather than a sideline of process engineering Emphasizes a problem solving and team learning approach. Assumes some knowledge of calculus, basic physical chemistry and basic transport phenomena as well as some inorganic and organic chemistry. |
| chemical engineering product development: Chemical Engineering Design Gavin Towler, Ray Sinnott, 2012-01-25 Chemical Engineering Design, Second Edition, deals with the application of chemical engineering principles to the design of chemical processes and equipment. Revised throughout, this edition has been specifically developed for the U.S. market. It provides the latest US codes and standards, including API, ASME and ISA design codes and ANSI standards. It contains new discussions of conceptual plant design, flowsheet development, and revamp design; extended coverage of capital cost estimation, process costing, and economics; and new chapters on equipment selection, reactor design, and solids handling processes. A rigorous pedagogy assists learning, with detailed worked examples, end of chapter exercises, plus supporting data, and Excel spreadsheet calculations, plus over 150 Patent References for downloading from the companion website. Extensive instructor resources, including 1170 lecture slides and a fully worked solutions manual are available to adopting instructors. This text is designed for chemical and biochemical engineering students (senior undergraduate year, plus appropriate for capstone design courses where taken, plus graduates) and lecturers/tutors, and professionals in industry (chemical process, biochemical, pharmaceutical, petrochemical sectors). New to this edition: - Revised organization into Part I: Process Design, and Part II: Plant Design. The broad themes of Part I are flowsheet development, economic analysis, safety and environmental impact and optimization. Part II contains chapters on equipment design and selection that can be used as supplements to a lecture course or as essential references for students or practicing engineers working on design projects. - New discussion of conceptual plant design, flowsheet development and revamp design - Significantly increased coverage of capital cost estimation, process costing and economics - New chapters on equipment selection, reactor design and solids handling processes - New sections on fermentation, adsorption, membrane separations, ion exchange and chromatography - Increased coverage of batch processing, food, pharmaceutical and biological processes - All equipment chapters in Part II revised and updated with current information - Updated throughout for latest US codes and standards, including API, ASME and ISA design codes and ANSI standards - Additional worked examples and homework problems - The most complete and up to date coverage of equipment selection - 108 realistic commercial design projects from diverse industries - A rigorous pedagogy assists learning, with detailed worked examples, end of chapter exercises, plus supporting data and Excel spreadsheet calculations plus over 150 Patent References, for downloading from the companion website - Extensive instructor resources: 1170 lecture slides plus fully worked solutions manual available to adopting instructors |
| chemical engineering product development: Chemical Engineering in the Pharmaceutical Industry David J. am Ende, 2011-03-10 This book deals with various unique elements in the drug development process within chemical engineering science and pharmaceutical R&D. The book is intended to be used as a professional reference and potentially as a text book reference in pharmaceutical engineering and pharmaceutical sciences. Many of the experimental methods related to pharmaceutical process development are learned on the job. This book is intended to provide many of those important concepts that R&D Engineers and manufacturing Engineers should know and be familiar if they are going to be successful in the Pharmaceutical Industry. These include basic analytics for quantitation of reaction components– often skipped in ChE Reaction Engineering and kinetics books. In addition Chemical Engineering in the Pharmaceutical Industry introduces contemporary methods of data analysis for kinetic modeling and extends these concepts into Quality by Design strategies for regulatory filings. For the current professionals, in-silico process modeling tools that streamline experimental screening approaches is also new and presented here. Continuous flow processing, although mainstream for ChE, is unique in this context given the range of scales and the complex economics associated with transforming existing batch-plant capacity. The book will be split into four distinct yet related parts. These parts will address the fundamentals of analytical techniques for engineers, thermodynamic modeling, and finally provides an appendix with common engineering tools and examples of their applications. |
| chemical engineering product development: Industrial Product Design of Solids and Liquids Wilfried Rähse, 2014-04-23 Offering invaluable insights from a chemist with over 35 years experience in the industry, this practical guide incorporates numerous practical examples and case studies to explain the concepts included here. The author explains the processes involved in product design, how to set up experiments, and ultimately how to scale-up. Among the host of topics covered is a discussion of recent advances in the fundamentals and innovative technologies leading to new and improved products. Industrial Product Design of Solids and Liquids: A Practical Guide is essential reading for the pharmaceutical, cosmetics and personal care, food, fragrance, paints, plastics and agricultural industries. |
| chemical engineering product development: Chemical Engineering: Visions of the World R. C. Darton, D. G. Wood, R. G. H. Prince, 2003-05-21 This book presents six visionary essays on the past, present and future of the chemical and process industries, together with a critical commentary. Our world is changing fast and the visions explore the implications for business and academic institutions, and for the professionals working in them. The visions were written and brought together for the 6th World Congress of Chemical Engineering in Melbourne, Australia in September 2001. · Identifies trends in the chemicals business environment and their consequences · Discusses a wide variety of views about business and technology · Describes the impact of newly developing technologies |
| chemical engineering product development: Chemical Product Design E. L. Cussler, G. D. Moggridge, 2001-04-09 Until recently, the chemical industry has been dominated by the manufacture of bulk commodity chemicals such as benzene, ammonia, and polypropylene. However, over the last decade a significant shift occurred. Now most chemical companies devote any new resources to the design and manufacture of specialty, high value-added chemical products such as pharmaceuticals, cosmetics, and electronic coatings. Although the jobs held by chemical engineers have also changed to reflect this altered business, their training has remained static, emphasizing traditional commodities. This ground-breaking text starts to redress the balance between commodities and higher value-added products. It expands the scope of chemical engineering design to encompass both process design and product design. The authors use a four-step procedure for chemical product design - needs, ideas, selection, manufacture - drawing numerous examples from industry to illustrate the discussion. The book concludes with a brief review of the economic issues. Chemical engineering students and beginning chemical engineers will find this text an inviting introduction to chemical product design. |
| chemical engineering product development: Product Design and Engineering Ulrich Bröckel, Willi Meier, Gerhard Wagner, 2013-08-02 Covering the whole value chain - from product requirements and properties via process technologies and equipment to real-world applications - this reference represents a comprehensive overview of the topic. The editors and majority of the authors are members of the European Federation of Chemical Engineering, with backgrounds from academia as well as industry. Therefore, this multifaceted area is highlighted from different angles: essential physico-chemical background, latest measurement and prediction techniques, and numerous applications from cosmetic up to food industry. Recommended reading for process, pharma and chemical engineers, chemists in industry, and those working in the pharmaceutical, food, cosmetics, dyes and pigments industries. |
| chemical engineering product development: Chemical Product Technology Dmitry Yu. Murzin, 2018-04-09 Chemical Product Technology focuses on materials chemistry and introduces industrial manufacturing technologies for different product types. The author presents a full cycle of product development for the materials that are used in everyday live, such as cosmetics, dyes, drugs, papers, textiles, agrochemicals, etc., starting from product selection and up to setup of manufacturing process. |
| chemical engineering product development: Design of Experiments in Chemical Engineering Zivorad R. Lazic, 2006-03-06 While existing books related to DOE are focused either on process or mixture factors or analyze specific tools from DOE science, this text is structured both horizontally and vertically, covering the three most common objectives of any experimental research: * screening designs * mathematical modeling, and * optimization. Written in a simple and lively manner and backed by current chemical product studies from all around the world, the book elucidates basic concepts of statistical methods, experiment design and optimization techniques as applied to chemistry and chemical engineering. Throughout, the focus is on unifying the theory and methodology of optimization with well-known statistical and experimental methods. The author draws on his own experience in research and development, resulting in a work that will assist students, scientists and engineers in using the concepts covered here in seeking optimum conditions for a chemical system or process. With 441 tables, 250 diagrams, as well as 200 examples drawn from current chemical product studies, this is an invaluable and convenient source of information for all those involved in process optimization. |
| chemical engineering product development: Simultaneous Engineering for New Product Development Jack Ribbens, 2000-02-14 An integrated, highly practical approach to product developmentusing simultaneous engineering Industrial engineers and designers as well as managers working on new product development (NPD) typically do not have the time or the expertise to get involved in functions outside their immediate area. Yet the very nature of NPD requires a number of functions and processes to be performed concurrently. This is where simultaneous engineering comes in. Simultaneous Engineering for New Product Development offers state-of-the-art, integrated coverage of these two hot topics in manufacturing. Industry expert Jack Ribbens draws on firsthand experience with the successful application of simultaneous engineering in the automotive industry, discussing how this approach can help streamline the entire development and production process, resulting in high-quality, competitive goods. He examines all phases of the process, devoting a chapter to each key element-from market research to design and engineering to manufacturing, selling, and customer service and support. And while most books on concurrent engineering stress the theoretical aspects of the field, Ribbens's book is decidedly practical, complete with case studies from the automotive, aerospace, heavy vehicle, and electronic industries that can be applied to any manufactured product. With mathematical model development as well as useful graphs, checklists, and references, Simultaneous Engineering for New Product Development will help manufacturing professionals take advantage of new trends and technologies in manufacturing well into the twenty-first century. |
| chemical engineering product development: Computer Aided Property Estimation for Process and Product Design Georgios M. Kontogeorgis, Rafiqul Gani, 2004-06-30 Properties of chemical compounds and their mixtures are needed in almost every aspect of process and product design. When the use of experimental data is not possible, one of the most widely used options in the use of property estimation models. Computer Aided Property Estimation for Process and Product Design provides a presentation of the most suitable property estimation models available today as well as guidelines on how to select an appropriate model. Problems that users are faced with, such as: which models to use and what their accuracy is, are addressed using a systematical approach to property estimation. The volume includes contributions from leading experts from academia and industry. A wide spectrum of properties and phase equilibria types is covered, making it indispensable for research, development and educational purposes.* This book presents the latest developments in computational modelling for thermodynamic property estimation.* It combines theory with practice and includes illustrative examples of software applications. * The questions users of property models are faced with are addressed comprehensively. |
| chemical engineering product development: Pharmaceutical Process Development John Blacker, Michael T Williams, 2011-08-17 Pharmaceutical process research and development is an exacting, multidisciplinary effort but a somewhat neglected discipline in the chemical curriculum. This book presents an overview of the many facets of process development and how recent advances in synthetic organic chemistry, process technology and chemical engineering have impacted on the manufacture of pharmaceuticals. In 15 concise chapters the book covers such diverse subjects as route selection and economics, the interface with medicinal chemistry, the impact of green chemistry, safety, the crucial role of physical organic measurements in gaining a deeper understanding of chemical behaviour, the role of the analyst, new tools and innovations in reactor design, purification and separation, solid state chemistry and its role in formulation. The book ends with an assessment of future trends and challenges. The book provides a valuable overview of: both early and late stage chemical development, how safe and scaleable synthetic routes are designed, selected and developed, the importance of the chemical engineering, analytical and manufacturing interfaces, the key enabling technologies, including catalysis and biocatalysis, the importance of the green chemical perspective and solid form issues. The book, written and edited by experts in the field, is a contemporary, holistic treatise, with a logical sequence for process development and mini-case histories within the chapters to bring alive different aspects of the process. It is completely pharmaceutical themed, encompassing all essential aspects, from route and reagent selection to manufacture of the active compound. The book is aimed at both graduates and postgraduates interested in a career in the pharmaceutical industry. It informs them about the breadth of the work carried out in chemical research and development departments, and gives them a feel for the challenges involved in the job. The book is also of value to academics who often understand the drug discovery arena, but have far less appreciation of the drug development area, and are thus unable to advise their students about the relative merits of careers in chemical development versus discovery. |
| chemical engineering product development: Integrated Design and Simulation of Chemical Processes Alexandre C. Dimian, Costin Sorin Bildea, Anton A. Kiss, 2014-09-18 This comprehensive work shows how to design and develop innovative, optimal and sustainable chemical processes by applying the principles of process systems engineering, leading to integrated sustainable processes with 'green' attributes. Generic systematic methods are employed, supported by intensive use of computer simulation as a powerful tool for mastering the complexity of physical models. New to the second edition are chapters on product design and batch processes with applications in specialty chemicals, process intensification methods for designing compact equipment with high energetic efficiency, plantwide control for managing the key factors affecting the plant dynamics and operation, health, safety and environment issues, as well as sustainability analysis for achieving high environmental performance. All chapters are completely rewritten or have been revised. This new edition is suitable as teaching material for Chemical Process and Product Design courses for graduate MSc students, being compatible with academic requirements world-wide. The inclusion of the newest design methods will be of great value to professional chemical engineers. - Systematic approach to developing innovative and sustainable chemical processes - Presents generic principles of process simulation for analysis, creation and assessment - Emphasis on sustainable development for the future of process industries |
| chemical engineering product development: Tools For Chemical Product Design Mariano Martín Martín, Mario R. Eden, Nishanth G. Chemmangattuvalappil, 2016-09-19 Tools for Chemical Product Design: From Consumer Products to Biomedicine describes the challenges involved in systematic product design across a variety of industries and provides a comprehensive overview of mathematical tools aimed at the design of chemical products, from molecular design to customer products. Chemical product design has become increasingly important over the past decade and includes a wide range of sectors including gasoline additives and blends in the petroleum industry, active ingredients and excipients in the pharmaceutical industry, and a variety of consumer products and specialty chemicals. Traditionally, such products have been designed through trial and error methods, which not only are time-consuming, but more importantly only provide limited knowledge that can be translated into next generation products. - Features an impressive collection of contributions from leading researchers in the field - Presents the latest tools available across a variety of industries - Describes the challenges involved in systematic product design as well as the latest methods for solving such problems - Covers a wide range of sectors including gasoline additives and blends in the petroleum industry, active ingredients and excipients in the pharmaceutical industry, and a variety of consumer products and specialty chemicals |
| chemical engineering product development: Chemical Engineering and Chemical Process Technology - Volume V Ryzhard Pohorecki, John Bridgwater, M. Molzahn. Rafiqul Gani and Crispulo Gallegos, 2010-11-30 Chemical Engineering and Chemical Process Technology is a theme component of Encyclopedia of Chemical Sciences, Engineering and Technology Resources in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty Encyclopedias. Chemical engineering is a branch of engineering, dealing with processes in which materials undergo changes in their physical or chemical state. These changes may concern size, energy content, composition and/or other application properties. Chemical engineering deals with many processes belonging to chemical industry or related industries (petrochemical, metallurgical, food, pharmaceutical, fine chemicals, coatings and colors, renewable raw materials, biotechnological, etc.), and finds application in manufacturing of such products as acids, alkalis, salts, fuels, fertilizers, crop protection agents, ceramics, glass, paper, colors, dyestuffs, plastics, cosmetics, vitamins and many others. It also plays significant role in environmental protection, biotechnology, nanotechnology, energy production and sustainable economical development. The Theme on Chemical Engineering and Chemical Process Technology deals, in five volumes and covers several topics such as: Fundamentals of Chemical Engineering; Unit Operations – Fluids; Unit Operations – Solids; Chemical Reaction Engineering; Process Development, Modeling, Optimization and Control; Process Management; The Future of Chemical Engineering; Chemical Engineering Education; Main Products, which are then expanded into multiple subtopics, each as a chapter. These five volumes are aimed at the following five major target audiences: University and College students Educators, Professional practitioners, Research personnel and Policy analysts, managers, and decision makers and NGOs. |
| chemical engineering product development: Process Development G. Herbert Vogel, 2006-03-06 Guiding readers through all steps of the complex process, this book covers the most diverse aspects of chemicals production, including those not or insufficiently covered in natural science courses. These comprise economic feasibility, patenting and licensing, demands on the location and the problem of waste disposal. Throughout, the author does not rely on simple references to other literature but instead reiterates many facts and places them in context, as well as succinctly explaining formulas, thus removing the need to look up items in secondary reference works. As such, the book is suitable for both newcomers as well as those already working in the field. Those working in R&D as well as plant managers will learn how to avoid pitfalls, resulting in higher safety. A common basis and indispensable ready reference for engineers and chemists. |
| chemical engineering product development: Sustainability in the Design, Synthesis and Analysis of Chemical Engineering Processes Gerardo Ruiz Mercado, Heriberto Cabezas, 2016-06-09 Sustainability in the Design, Synthesis and Analysis of Chemical Engineering Processes is an edited collection of contributions from leaders in their field. It takes a holistic view of sustainability in chemical and process engineering design, and incorporates economic analysis and human dimensions. Ruiz-Mercado and Cabezas have brought to this book their experience of researching sustainable process design and life cycle sustainability evaluation to assist with development in government, industry and academia. This book takes a practical, step-by-step approach to designing sustainable plants and processes by starting from chemical engineering fundamentals. This method enables readers to achieve new process design approaches with high influence and less complexity. It will also help to incorporate sustainability at the early stages of project life, and build up multiple systems level perspectives. Ruiz-Mercado and Cabezas' book is the only book on the market that looks at process sustainability from a chemical engineering fundamentals perspective. - Improve plants, processes and products with sustainability in mind; from conceptual design to life cycle assessment - Avoid retro fitting costs by planning for sustainability concerns at the start of the design process - Link sustainability to the chemical engineering fundamentals |
| chemical engineering product development: International Benchmarking of U.S. Chemical Engineering Research Competitiveness National Research Council, Division on Earth and Life Studies, Board on Chemical Sciences and Technology, Panel on Benchmarking the Research Competitiveness of the U.S. in Chemical Engineering, 2007-07-12 More than $400 billion worth of products rely on innovations in chemistry. Chemical engineering, as an academic discipline and profession, has enabled this achievement. In response to growing concerns about the future of the discipline, International Benchmarking of U.S. Chemical Engineering Research Competitiveness gauges the standing of the U.S. chemical engineering enterprise in the world. This in-depth benchmarking analysis is based on measures including numbers of published papers, citations, trends in degrees conferred, patent productivity, and awards. The book concludes that the United States is presently, and is expected to remain, among the world's leaders in all subareas of chemical engineering research. However, U.S. leadership in some classical and emerging subareas will be strongly challenged. This critical analysis will be of interest to practicing chemical engineers, professors and students in the discipline, economists, policy makers, major research university administrators, and executives in industries dependent upon innovations in chemistry. |
| chemical engineering product development: Product and Process Design Jan Harmsen, André B. de Haan, Pieter L. J. Swinkels, 2018-05-22 Product and Process Design: Driving Innovation is a comprehensive textbook for students and industrial professionals. It treats the combined design of innovative products and their innovative manufacturing processes, providing specific methods for BSc, MSc, PDEng and PhD courses. Students, industrial innovators and managers are guided through all design steps in all innovation stages (discovery, concept, feasibility, development, detailed engineering, and implementation) to successfully obtain novel products and their novel processes. The authors’ decades of innovation experience in industry, as well as in teaching BSc, MSc, and post-academic product and process design courses, thereby including the latest design publications, culminate in this book. |
| chemical engineering product development: Sustainability Engineering Jeffery Perl, 2016-07-07 This book explores sustainability engineering through the lens of the manufacturing and chemical process industries to elucidate the safe and economic implementation of process designs used to transform raw materials into useful finished products. The author applies the tenets of sustainability science to develop an engineering methodology that supports the perpetual availability of raw materials through recycling/reuse/repurposing, incorporates inexhaustible supplies, such as solar energy and municipal waste, and encompasses the husbandry of these resources in a manner that minimizes negative environmental impacts. Anyone involved in the design or manufacture of chemicals, or the upgrade of existing manufacturing processes, will benefit from this book’s suggestions for identifying improvement options, while adding the pivotal aspect of sustainability to the usual cost and safety equation optimization elements. |
| chemical engineering product development: Process Engineering and Industrial Management Jean-Pierre Dal Pont, 2013-03-04 Process Engineering, the science and art of transforming raw materials and energy into a vast array of commercial materials, was conceived at the end of the 19th Century. Its history in the role of the Process Industries has been quite honorable, and techniques and products have contributed to improve health, welfare and quality of life. Today, industrial enterprises, which are still a major source of wealth, have to deal with new challenges in a global world. They need to reconsider their strategy taking into account environmental constraints, social requirements, profit, competition, and resource depletion. “Systems thinking” is a prerequisite from process development at the lab level to good project management. New manufacturing concepts have to be considered, taking into account LCA, supply chain management, recycling, plant flexibility, continuous development, process intensification and innovation. This book combines experience from academia and industry in the field of industrialization, i.e. in all processes involved in the conversion of research into successful operations. Enterprises are facing major challenges in a world of fierce competition and globalization. Process engineering techniques provide Process Industries with the necessary tools to cope with these issues. The chapters of this book give a new approach to the management of technology, projects and manufacturing. Contents Part 1: The Company as of Today 1. The Industrial Company: its Purpose, History, Context, and its Tomorrow?, Jean-Pierre Dal Pont. 2. The Two Modes of Operation of the Company – Operational and Entrepreneurial, Jean-Pierre Dal Pont. 3. The Strategic Management of the Company: Industrial Aspects, Jean-Pierre Dal Pont. Part 2: Process Development and Industrialization 4. Chemical Engineering and Process Engineering, Jean-Pierre Dal Pont. 5. Foundations of Process Industrialization, Jean-François Joly. 6. The Industrialization Process: Preliminary Projects, Jean-Pierre Dal Pont and Michel Royer. 7. Lifecycle Analysis and Eco-Design: Innovation Tools for Sustainable Industrial Chemistry, Sylvain Caillol. 8. Methods for Design and Evaluation of Sustainable Processes and Industrial Systems, Catherine Azzaro-Pantel. 9. Project Management Techniques: Engineering, Jean-Pierre Dal Pont. Part 3: The Necessary Adaptation of the Company for the Future 10. Japanese Methods, Jean-Pierre Dal Pont. 11. Innovation in Chemical Engineering Industries, Oliver Potier and Mauricio Camargo. 12. The Place of Intensified Processes in the Plant of the Future, Laurent Falk. 13. Change Management, Jean-Pierre Dal Pont. 14. The Plant of the Future, Jean-Pierre Dal Pont. |
| chemical engineering product development: Introduction to Chemical Engineering Uche P. Nnaji, 2019-10-10 The field of chemical engineering is undergoing a global “renaissance,” with new processes, equipment, and sources changing literally every day. It is a dynamic, important area of study and the basis for some of the most lucrative and integral fields of science. Introduction to Chemical Engineering offers a comprehensive overview of the concept, principles and applications of chemical engineering. It explains the distinct chemical engineering knowledge which gave rise to a general-purpose technology and broadest engineering field. The book serves as a conduit between college education and the real-world chemical engineering practice. It answers many questions students and young engineers often ask which include: How is what I studied in the classroom being applied in the industrial setting? What steps do I need to take to become a professional chemical engineer? What are the career diversities in chemical engineering and the engineering knowledge required? How is chemical engineering design done in real-world? What are the chemical engineering computer tools and their applications? What are the prospects, present and future challenges of chemical engineering? And so on. It also provides the information new chemical engineering hires would need to excel and cross the critical novice engineer stage of their career. It is expected that this book will enhance students understanding and performance in the field and the development of the profession worldwide. Whether a new-hire engineer or a veteran in the field, this is a must—have volume for any chemical engineer’s library. |
| chemical engineering product development: Integrated Design Engineering Sándor Vajna, 2020-08-25 This book addresses Integrated Design Engineering (IDE), which represents a further development of Integrated Product Development (IPD) into an interdisciplinary model for both a human-centred and holistic product development. The book covers the systematic use of integrated, interdisciplinary, holistic and computer-aided strategies, methods and tools for the development of products and services, taking into account the entire product lifecycle. Being applicable to various kinds of products (manufactured, software, services, etc.), it helps readers to approach product development in a synthesised and integrated way. The book explains the basic principles of IDE and its practical application. IDE’s usefulness has been demonstrated in case studies on actual industrial projects carried out by all book authors. A neutral methodology is supplied that allows the reader to choose the appropriate working practices and performance assessment techniques to develop their product quickly and efficiently. Given its manifold topics, the book offers a valuable reference guide for students in engineering, industrial design, economics and computer science, product developers and managers in industry, as well as industrial engineers and technicians. |
| chemical engineering product development: Production Management of Chemical Industries Kiran R. Golwalkar, 2016-02-08 This book covers all major areas of operation, pollution control, safety, modernization, diversification, and resource management for cost control in the industrial production of chemicals. The author details the importance of obtaining the right type of raw materials and equipment for maximum plant efficiency and discusses revival of plants that have been idle for long periods. He also presents important issues concerning product quality, energy recovery, safety, pollution control and improving profitability by proper management of resources. The book is ideal for shop floor engineers, middle level management, and owners of small- and medium-scale facilities in many countries as it serves as a guide for keeping the plant operations running in adverse situations, for reducing energy consumption; improving profitability, resource allocation, and workforce planning. |
| chemical engineering product development: 化学工程 John Francis Richardson, John Rayner Backhurst, 2008 本书内容包括:蒸馏;气体吸收;液-液萃取;蒸发;结晶;干燥;吸附;离子交换;色谱分离;产品设计与过程强化等。 |
| chemical engineering product development: Beyond the Molecular Frontier National Research Council, Division on Earth and Life Studies, Board on Chemical Sciences and Technology, Committee on Challenges for the Chemical Sciences in the 21st Century, 2003-03-19 Chemistry and chemical engineering have changed significantly in the last decade. They have broadened their scopeâ€into biology, nanotechnology, materials science, computation, and advanced methods of process systems engineering and controlâ€so much that the programs in most chemistry and chemical engineering departments now barely resemble the classical notion of chemistry. Beyond the Molecular Frontier brings together research, discovery, and invention across the entire spectrum of the chemical sciencesâ€from fundamental, molecular-level chemistry to large-scale chemical processing technology. This reflects the way the field has evolved, the synergy at universities between research and education in chemistry and chemical engineering, and the way chemists and chemical engineers work together in industry. The astonishing developments in science and engineering during the 20th century have made it possible to dream of new goals that might previously have been considered unthinkable. This book identifies the key opportunities and challenges for the chemical sciences, from basic research to societal needs and from terrorism defense to environmental protection, and it looks at the ways in which chemists and chemical engineers can work together to contribute to an improved future. |
| chemical engineering product development: Analysis, Synthesis and Design of Chemical Processes Richard Turton, Richard C. Bailie, Wallace B. Whiting, Joseph A. Shaeiwitz, 2008-12-24 The Leading Integrated Chemical Process Design Guide: Now with New Problems, New Projects, and More More than ever, effective design is the focal point of sound chemical engineering. Analysis, Synthesis, and Design of Chemical Processes, Third Edition, presents design as a creative process that integrates both the big picture and the small details–and knows which to stress when, and why. Realistic from start to finish, this book moves readers beyond classroom exercises into open-ended, real-world process problem solving. The authors introduce integrated techniques for every facet of the discipline, from finance to operations, new plant design to existing process optimization. This fully updated Third Edition presents entirely new problems at the end of every chapter. It also adds extensive coverage of batch process design, including realistic examples of equipment sizing for batch sequencing; batch scheduling for multi-product plants; improving production via intermediate storage and parallel equipment; and new optimization techniques specifically for batch processes. Coverage includes Conceptualizing and analyzing chemical processes: flow diagrams, tracing, process conditions, and more Chemical process economics: analyzing capital and manufacturing costs, and predicting or assessing profitability Synthesizing and optimizing chemical processing: experience-based principles, BFD/PFD, simulations, and more Analyzing process performance via I/O models, performance curves, and other tools Process troubleshooting and “debottlenecking” Chemical engineering design and society: ethics, professionalism, health, safety, and new “green engineering” techniques Participating successfully in chemical engineering design teams Analysis, Synthesis, and Design of Chemical Processes, Third Edition, draws on nearly 35 years of innovative chemical engineering instruction at West Virginia University. It includes suggested curricula for both single-semester and year-long design courses; case studies and design projects with practical applications; and appendixes with current equipment cost data and preliminary design information for eleven chemical processes–including seven brand new to this edition. |
| chemical engineering product development: Chemical and Bioprocess Engineering Shirish Sonawane, Y. Pydi Setty, Srinu Naik Sapavatu, 2015-04-15 Examining energy, environment, and sustainability from the chemical engineering point of view, this book highlights critical issues faced by chemical engineers and biochemical engineers worldwide. The book covers recent trends in chemical engineering and bioprocess engineering, such as CFD simulation, statistical optimization, process control, |
| chemical engineering product development: Preparing Chemists and Chemical Engineers for a Globally Oriented Workforce National Research Council, Division on Earth and Life Studies, Board on Chemical Sciences and Technology, Chemical Sciences Roundtable, 2004-09-02 Globalizationâ€the flow of people, goods, services, capital, and technology across international bordersâ€is significantly impacting the chemistry and chemical engineering professions. Chemical companies are seeking new ideas, a trained workforce, and new market opportunities regardless of geographic location. During an October 2003 workshop, leaders in chemistry and chemical engineering from industry, academia, government, and private funding organizations explored the implications of an increasingly global research environment for the chemistry and chemical engineering workforce. The workshop presentations described deficiencies in the current educational system and the need to create and sustain a globally aware workforce in the near future. The goal of the workshop was to inform the Chemical Sciences Roundtable, which provides a science-oriented, apolitical forum for leaders in the chemical sciences to discuss chemically related issues affecting government, industry, and universities. |
| chemical engineering product development: Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture Gintaras V. Reklaitis, Christine Seymour, Salvador García-Munoz, 2017-10-09 Covers a widespread view of Quality by Design (QbD) encompassing the many stages involved in the development of a new drug product. The book provides a broad view of Quality by Design (QbD) and shows how QbD concepts and analysis facilitate the development and manufacture of high quality products. QbD is seen as a framework for building process understanding, for implementing robust and effective manufacturing processes and provides the underpinnings for a science-based regulation of the pharmaceutical industry. Edited by the three renowned researchers in the field, Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture guides pharmaceutical engineers and scientists involved in product and process development, as well as teachers, on how to utilize QbD practices and applications effectively while complying with government regulations. The material is divided into three main sections: the first six chapters address the role of key technologies, including process modeling, process analytical technology, automated process control and statistical methodology in supporting QbD and establishing the associated design space. The second section consisting of seven chapters present a range of thoroughly developed case studies in which the tools and methodologies discussed in the first section are used to support specific drug substance and drug-product QbD related developments. The last section discussed the needs for integrated tools and reviews the status of information technology tools available for systematic data and knowledge management to support QbD and related activities. Highlights Demonstrates Quality by Design (QbD) concepts through concrete detailed industrial case studies involving of the use of best practices and assessment of regulatory implications Chapters are devoted to applications of QbD methodology in three main processing sectors—drug substance process development, oral drug product manufacture, parenteral product processing, and solid-liquid processing Reviews the spectrum of process model types and their relevance, the range of state-of-the-art real-time monitoring tools and chemometrics, and alternative automatic process control strategies and methods for both batch and continuous processes The role of the design space is demonstrated through specific examples and the importance of understanding the risk management aspects of design space definition is highlighted Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture is an ideal book for practitioners, researchers, and graduate students involved in the development, research, or studying of a new drug and its associated manufacturing process. |
| chemical engineering product development: Chemical Product Design and Formulation Ali Elkamel, Hesham Alhumade, Navid Omidbakhsh, Keyvan Nowruzi, Thomas Duever, 2023-04-03 Chemical Product Formulation Design and Optimization Explore the cutting-edge in chemical product formulation and design In Chemical Product Formulation Design and Optimization: Methods, Techniques, and Case Studies, a team of renowned technologists and engineers delivers a practice guide to chemical product design. Offering real-world case studies for disinfectant formulation, the optimization of defined media, and the formulation of biocomposites, the book contains introduction to the current product design process. In addition to the background of related statistical techniques, readers will find: Clear illustrations, figures, and tables that improve understanding and retention of critical topics Thorough introductions to the mathematical principles of chemical product design A complete examination of intellectual property considerations in the chemical product design process Ideal for process and chemical engineers, Chemical Product Formulation Design and Optimization: Methods, Techniques, and Case Studies is a must-read resource for professionals in the pharmaceutical and cosmetics industry as well as chemical engineers working in the food, paint, and dye industries who seek a one-stop resource that includes the latest advances in chemical product formulation. |
| chemical engineering product development: Product-Driven Process Design Edwin Zondervan, Cristhian Almeida-Rivera, Kyle Vincent Camarda, 2020-01-20 Product-driven process design – from molecule to enterprise provides process engineers and process engineering students with access to a modern and stimulating methodology to process and product design. Throughout the book the links between product design and process design become evident while the reader is guided step-by-step through the different stages of the intertwining product and process design activities. Both molecular and enterprise-wide considerations in design are introduced and addressed in detail. Several examples and case studies in emerging areas such as bio- and food-systems, pharmaceuticals and energy are discussed and presented. This book is an excellent guide and companion for undergraduate, graduate students as well as professional practitioners. |
| chemical engineering product development: Chemical Engineering in the Pharmaceutical Industry Mary T. am Ende, David J. am Ende, 2019-04-09 A guide to the important chemical engineering concepts for the development of new drugs, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry offers a guide to the experimental and computational methods related to drug product design and development. The second edition has been greatly expanded and covers a range of topics related to formulation design and process development of drug products. The authors review basic analytics for quantitation of drug product quality attributes, such as potency, purity, content uniformity, and dissolution, that are addressed with consideration of the applied statistics, process analytical technology, and process control. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The contributors explore technology transfer and scale-up of batch processes that are exemplified experimentally and computationally. Written for engineers working in the field, the book examines in-silico process modeling tools that streamline experimental screening approaches. In addition, the authors discuss the emerging field of continuous drug product manufacturing. This revised second edition: Contains 21 new or revised chapters, including chapters on quality by design, computational approaches for drug product modeling, process design with PAT and process control, engineering challenges and solutions Covers chemistry and engineering activities related to dosage form design, and process development, and scale-up Offers analytical methods and applied statistics that highlight drug product quality attributes as design features Presents updated and new example calculations and associated solutions Includes contributions from leading experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduation students, and professionals in the field of pharmaceutical sciences and manufacturing, Chemical Engineering in the Pharmaceutical Industry, Second Edition contains information designed to be of use from the engineer's perspective and spans information from solid to semi-solid to lyophilized drug products. |
| chemical engineering product development: Towards Sustainable Chemical Processes Jingzheng Ren, Yufei Wang, Chang He, 2020-06-30 Towards Sustainable Chemical Processes describes a comprehensive framework for sustainability assessment, design and the processes optimization of chemical engineering. Beginning with the analysis and assessment in the early stage of chemical products' initiating, this book focuses on the combination of science sustainability and process system engineering, involving mathematical models, industrial ecology, circular economy, energy planning, process integration and sustainability engineering.All chapters throughout answered two fundamental questions in depth: (1) what tools and models are available to be used to assess and design sustainable chemical processes, (2) what the core theories and concepts are to get into the sustainable chemical process fields. Therefore, Towards Sustainable Chemical Processes is an indispensable guide for chemical engineers, researchers, students, practitioners and consultants in sustainability related area. - Provides innovative, novel and comprehensive methods and models for sustainability assessment, design and optimization, and synthesis and integration of chemical engineering processes - Combines sustainability science with process system engineering - Integrates mathematical models, industrial ecology, circular economy, energy planning, process integration and sustainability engineering - Includes new case studies related to renewable energy, resource management, process synthesis and process integration |
Chemical compound | Definition, Examples, & Types | Britannica
Chemical compound, any substance composed of identical molecules consisting of atoms of two or more chemical elements. All the matter in the universe is composed of the atoms of more …
Chemical reaction | Definition, Equations, Examples, & Types
May 12, 2025 · A chemical reaction is a process in which one or more substances, the reactants, are converted to one or more different substances, the products. Substances are either …
Chemistry | Definition, Topics, Types, History, & Facts | Britannica
Apr 24, 2025 · Most of the materials that occur on Earth, such as wood, coal, minerals, or air, are mixtures of many different and distinct chemical substances. Each pure chemical substance …
Periodic table | Definition, Elements, Groups, Charges, Trends,
May 10, 2025 · The periodic table is a tabular array of the chemical elements organized by atomic number, from the element with the lowest atomic number, hydrogen, to the element with the …
Chemical element | Definition, Origins, Distribution, & Facts
Apr 29, 2025 · A chemical element is any substance that cannot be decomposed into simpler substances by ordinary chemical processes. Elements are the fundamental materials of which …
Benzene | Definition, Discovery, Structure, Properties, & Uses
May 9, 2025 · chemical bonding in benzene Benzene is the smallest of the organic aromatic hydrocarbons. It contains sigma bonds (represented by lines) and regions of high-pi electron …
Sodium hydroxide | Definition, Common Name, & Uses | Britannica
Chemical Safety Facts - Sodium Hydroxide; The Essential Chemical Industry - online - Sodium hydroxide
Reaction rate | Facts & Formula | Britannica
reaction rate, in chemistry, the speed at which a chemical reaction proceeds. It is often expressed in terms of either the concentration (amount per unit volume) of a product that is formed in a …
Nitrous oxide | Definition, Formula, Uses, Effects, & Facts - Britannica
May 15, 2025 · Nitrous oxide, also called laughing gas, one of several oxides of nitrogen, a colorless gas with pleasant, sweetish odor and taste, which when inhaled produces …
Alcohol Metabolism, Carcinogen, Toxicity - Britannica
Acetaldehyde (CH3CHO), an aldehyde used as a starting material in the synthesis of 1-butanol (n-butyl alcohol), ethyl acetate, perfumes, flavourings, aniline dyes, plastics, synthetic rubber, and …
Chemical compound | Definition, Examples, & Types | Britannica
Chemical compound, any substance composed of identical molecules consisting of atoms of two or more chemical elements. All the matter in the universe is composed of the atoms of more …
Chemical reaction | Definition, Equations, Examples, & Types
May 12, 2025 · A chemical reaction is a process in which one or more substances, the reactants, are converted to one or more different substances, the products. Substances are either …
Chemistry | Definition, Topics, Types, History, & Facts | Britannica
Apr 24, 2025 · Most of the materials that occur on Earth, such as wood, coal, minerals, or air, are mixtures of many different and distinct chemical substances. Each pure chemical substance …
Periodic table | Definition, Elements, Groups, Charges, Trends,
May 10, 2025 · The periodic table is a tabular array of the chemical elements organized by atomic number, from the element with the lowest atomic number, hydrogen, to the element with the …
Chemical element | Definition, Origins, Distribution, & Facts
Apr 29, 2025 · A chemical element is any substance that cannot be decomposed into simpler substances by ordinary chemical processes. Elements are the fundamental materials of which …
Benzene | Definition, Discovery, Structure, Properties, & Uses
May 9, 2025 · chemical bonding in benzene Benzene is the smallest of the organic aromatic hydrocarbons. It contains sigma bonds (represented by lines) and regions of high-pi electron …
Sodium hydroxide | Definition, Common Name, & Uses | Britannica
Chemical Safety Facts - Sodium Hydroxide; The Essential Chemical Industry - online - Sodium hydroxide
Reaction rate | Facts & Formula | Britannica
reaction rate, in chemistry, the speed at which a chemical reaction proceeds. It is often expressed in terms of either the concentration (amount per unit volume) of a product that is formed in a …
Nitrous oxide | Definition, Formula, Uses, Effects, & Facts - Britannica
May 15, 2025 · Nitrous oxide, also called laughing gas, one of several oxides of nitrogen, a colorless gas with pleasant, sweetish odor and taste, which when inhaled produces …
Alcohol Metabolism, Carcinogen, Toxicity - Britannica
Acetaldehyde (CH3CHO), an aldehyde used as a starting material in the synthesis of 1-butanol (n-butyl alcohol), ethyl acetate, perfumes, flavourings, aniline dyes, plastics, synthetic rubber, and …
