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chemical eric case study: Oil Spill Environmental Forensics Case Studies Scott Stout, Zhendi Wang, 2017-10-22 Oil Spill Environmental Forensics Case Studies includes 34 chapters that serve to present various aspects of environmental forensics in relation to real-world oil spill case studies from around the globe. Authors representing academic, government, and private researcher groups from 14 countries bring a diverse and global perspective to this volume. Oil Spill Environmental Forensics Case Studies addresses releases of natural gas/methane, automotive gasoline and other petroleum fuels, lubricants, vegetable oils, paraffin waxes, bitumen, manufactured gas plant residues, urban runoff, and, of course, crude oil, the latter ranging from light Bakken shale oil to heavy Canadian oil sands oil. New challenges surrounding forensic investigations of stray gas in the shallow subsurface, volatiles in air, dissolved chemicals in water (including passive samplers), and biological tissues associated with oil spills are included, as are the effects and long-term oil weathering, long-term monitoring in urbanized and non-urbanized environments, fate and transport, forensic historical research, new analytical and chemical data processing and interpretation methods. - Presents cases in each chapter on the application of specific oil spill environmental forensic techniques - Features chapters written by international experts from both academia and industry - Includes relevant concepts and theories elucidated for each theme |
chemical eric case study: Inventing Adulthoods Sheila Henderson, 2007 This text is written through case studies and interviews. |
chemical eric case study: Rural Poverty in the United States Ann R. Tickamyer, Jennifer Sherman, Jennifer Warlick, 2017-08-22 America's rural areas have always held a disproportionate share of the nation's poorest populations. Rural Poverty in the United States examines why. What is it about the geography, demography, and history of rural communities that keeps them poor? In a comprehensive analysis that extends from the Civil War to the present, Rural Poverty in the United States looks at access to human and social capital; food security; healthcare and the environment; homelessness; gender roles and relations; racial inequalities; and immigration trends to isolate the underlying causes of persistent rural poverty. Contributors to this volume incorporate approaches from multiple disciplines, including sociology, economics, demography, race and gender studies, public health, education, criminal justice, social welfare, and other social science fields. They take a hard look at current and past programs to alleviate rural poverty and use their failures to suggest alternatives that could improve the well-being of rural Americans for years to come. These essays work hard to define rural poverty's specific metrics and markers, a critical step for building better policy and practice. Considering gender, race, and immigration, the book appreciates the overlooked structural and institutional dimensions of ongoing rural poverty and its larger social consequences. |
chemical eric case study: State-Of-the-Art and Emerging Technologies for Therapeutic Monoclonal Antibody Characterization Volume 2. Biopharmaceutical Characterization John E. Schiel, Darryl L. Davis, Oleg V. Borisov, Oleg Borisov, 2016-06-24 Distributed in print by Oxford University Press. |
chemical eric case study: Start with a Story Clyde Freeman Herreid, 2007 Kipp Herreid learned other ways to teach- much better ways. His favorite approach puts science in vivid context through case studies, which he calls stories with an educational message. This compilation of 40-plus essays examines every aspect of the case study method.--[back cover]. |
chemical eric case study: Philosophy of Chemistry Eric Scerri, Lee McIntyre, 2014-11-11 This volume follows the successful book, which has helped to introduce and spread the Philosophy of Chemistry to a wider audience of philosophers, historians, science educators as well as chemists, physicists and biologists. The introduction summarizes the way in which the field has developed in the ten years since the previous volume was conceived and introduces several new authors who did not contribute to the first edition. The editors are well placed to assemble this book, as they are the editor in chief and deputy editors of the leading academic journal in the field, Foundations of Chemistry. The philosophy of chemistry remains a somewhat neglected field, unlike the philosophy of physics and the philosophy of biology. Why there has been little philosophical attention to the central discipline of chemistry among the three natural sciences is a theme that is explored by several of the contributors. This volume will do a great deal to redress this imbalance. Among the themes covered is the question of reduction of chemistry to physics, the reduction of biology to chemistry, whether true chemical laws exist and causality in chemistry. In addition more general questions of the nature of organic chemistry, biochemistry and chemical synthesis are examined by specialist in these areas. |
chemical eric case study: Strengthening the Linkages Between the Sciences and the Mathematical Sciences National Research Council, Commission on Physical Sciences, Mathematics, and Applications, Committee on Strengthening the Linkages Between the Sciences and the Mathematical Sciences, 2000-04-05 Over three hundred years ago, Galileo is reported to have said, The laws of nature are written in the language of mathematics. Often mathematics and science go hand in hand, with one helping develop and improve the other. Discoveries in science, for example, open up new advances in statistics, computer science, operations research, and pure and applied mathematics which in turn enabled new practical technologies and advanced entirely new frontiers of science. Despite the interdependency that exists between these two disciplines, cooperation and collaboration between mathematical scientists and scientists have only occurred by chance. To encourage new collaboration between the mathematical sciences and other fields and to sustain present collaboration, the National Research Council (NRC) formed a committee representing a broad cross-section of scientists from academia, federal government laboratories, and industry. The goal of the committee was to examine the mechanisms for strengthening interdisciplinary research between mathematical sciences and the sciences, with a strong focus on suggesting the most effective mechanisms of collaboration. Strengthening the Linkages Between the Sciences and the Mathematical Sciences provides the findings and recommendations of the committee as well as case studies of cross-discipline collaboration, the workshop agenda, and federal agencies that provide funding for such collaboration. |
chemical eric case study: Understanding Physics and Physical Chemistry Using Formal Graphs Eric Vieil, 2012-02-23 The subject of this book is truly original. By encoding of algebraic equations into graphs-originally a purely pedagogical technique-the exploration of physics and physical chemistry reveals common pictures through all disciplines. The hidden structure of the scientific formalism that appears is a source of astonishment and provides efficient simpl |
chemical eric case study: Clinical Case Studies for the Family Nurse Practitioner Leslie Neal-Boylan, 2011-11-28 Clinical Case Studies for the Family Nurse Practitioner is a key resource for advanced practice nurses and graduate students seeking to test their skills in assessing, diagnosing, and managing cases in family and primary care. Composed of more than 70 cases ranging from common to unique, the book compiles years of experience from experts in the field. It is organized chronologically, presenting cases from neonatal to geriatric care in a standard approach built on the SOAP format. This includes differential diagnosis and a series of critical thinking questions ideal for self-assessment or classroom use. |
chemical eric case study: The Research Manual Evelyn Marcussen Hatch, Anne Lazaraton, 1991 |
chemical eric case study: Philosophy of Chemistry Davis Baird, Eric Scerri, Lee McIntyre, 2011-09-01 This comprehensive volume marks a new standard in scholarship in the emerging field of the philosophy of chemistry. Philosophers, chemists, and historians of science ask some fundamental questions about the relationship between philosophy and chemistry. |
chemical eric case study: Case Studies in Science Education: The case reports , 1978 |
chemical eric case study: Cambridge Handbook of Engineering Education Research Aditya Johri, Barbara M. Olds, 2014-02-10 The Cambridge Handbook of Engineering Education Research is the critical reference source for the growing field of engineering education research, featuring the work of world luminaries writing to define and inform this emerging field. The Handbook draws extensively on contemporary research in the learning sciences, examining how technology affects learners and learning environments, and the role of social context in learning. Since a landmark issue of the Journal of Engineering Education (2005), in which senior scholars argued for a stronger theoretical and empirically driven agenda, engineering education has quickly emerged as a research-driven field increasing in both theoretical and empirical work drawing on many social science disciplines, disciplinary engineering knowledge, and computing. The Handbook is based on the research agenda from a series of interdisciplinary colloquia funded by the US National Science Foundation and published in the Journal of Engineering Education in October 2006. |
chemical eric case study: Environmental Medicine Committee on Curriculum Development in Environmental Medicine, Institute of Medicine, 1995-05-12 People are increasingly concerned about potential environmental health hazards and often ask their physicians questions such as: Is the tap water safe to drink? Is it safe to live near power lines? Unfortunately, physicians often lack the information and training related to environmental health risks needed to answer such questions. This book discusses six competency based learning objectives for all medical school students, discusses the relevance of environmental health to specific courses and clerkships, and demonstrates how to integrate environmental health into the curriculum through published case studies, some of which are included in one of the book's three appendices. Also included is a guide on where to obtain additional information for treatment, referral, and follow-up for diseases with possible environmental and/or occupational origins. |
chemical eric case study: The Impact of School Infrastructure on Learning Peter Barrett, Alberto Treves, Tigran Shmis, Diego Ambasz, 2019-02-04 'The Impact of School Infrastructure on Learning: A Synthesis of the Evidence provides an excellent literature review of the resources that explore the areas of focus for improved student learning, particularly the aspiration for “accessible, well-built, child-centered, synergetic and fully realized learning environments.†? Written in a style which is both clear and accessible, it is a practical reference for senior government officials and professionals involved in the planning and design of educational facilities, as well as for educators and school leaders. --Yuri Belfali, Head of Division, Early Childhood and Schools, OECD Directorate for Education and Skills This is an important and welcome addition to the surprisingly small, evidence base on the impacts of school infrastructure given the capital investment involved. It will provide policy makers, practitioners, and those who are about to commission a new build with an important and comprehensive point of reference. The emphasis on safe and healthy spaces for teaching and learning is particularly welcome. --Harry Daniels, Professor of Education, Department of Education, Oxford University, UK This report offers a useful library of recent research to support the, connection between facility quality and student outcomes. At the same time, it also points to the unmet need for research to provide verifiable and reliable information on this connection. With such evidence, decisionmakers will be better positioned to accurately balance the allocation of limited resources among the multiple competing dimensions of school policy, including the construction and maintenance of the school facility. --David Lever, K-12 Facility Planner, Former Executive Director of the Interagency Committee on School Construction, Maryland Many planners and designers are seeking a succinct body of research defining both the issues surrounding the global planning of facilities as well as the educational outcomes based on the quality of the space provided. The authors have finally brought that body of evidence together in this well-structured report. The case for better educational facilities is clearly defined and resources are succinctly identified to stimulate the dialogue to come. We should all join this conversation to further the process of globally enhancing learning-environment quality! --David Schrader, AIA, Educational Facility Planner and Designer, Former Chairman of the Board of Directors, Association for Learning Environments (A4LE) |
chemical eric case study: Design for the Environment Screen Printing Case Study 3 , 1996 |
chemical eric case study: Oil Spill Environmental Forensics Zhendi Wang, Scott Stout, 2010-07-26 Oil Spill Environmental Forensics provides a complete view of the various forensic techniques used to identify the source of an oil spill into the environment. The forensic procedures described within represent various methods from scientists throughout the world. The authors explore which analytical and interpretative techniques are best suited for a particular oil spill project. This handy reference also explores the use of these techniques in actual environmental oil spills. Famous incidents discussed include the Exxon Valdez incident in 1989 and the Guanabara Bay, Brazil 2000. The authors chronicle both the successes and failures of the techniques used for each of these events. Dr. Zhendi Wang is a senior research scientist and Head of Oil Spill Research of Environment Canada, working in the oil and toxic chemical spill research field. He has authored over 270 academic publications and won a number of national and international scientific honors and awards. Dr. Wang is a member of American Chemical Society (ACS), the Canadian Society for Chemistry (CSC), and the International Society of Environmental Forensics (ISEF). - International experts show readers the forensic techniques used in oil spill investigations - Provides the theoretical basis and practical applications for investigative techniques - Contains numerous case studies demonstrating proven technique |
chemical eric case study: Modeling of Atmospheric Chemistry Guy P. Brasseur, Daniel J. Jacob, 2017-05-04 Mathematical modeling of atmospheric composition is a formidable scientific and computational challenge. This comprehensive presentation of the modeling methods used in atmospheric chemistry focuses on both theory and practice, from the fundamental principles behind models, through to their applications in interpreting observations. An encyclopaedic coverage of methods used in atmospheric modeling, including their advantages and disadvantages, makes this a one-stop resource with a large scope. Particular emphasis is given to the mathematical formulation of chemical, radiative, and aerosol processes; advection and turbulent transport; emission and deposition processes; as well as major chapters on model evaluation and inverse modeling. The modeling of atmospheric chemistry is an intrinsically interdisciplinary endeavour, bringing together meteorology, radiative transfer, physical chemistry and biogeochemistry, making the book of value to a broad readership. Introductory chapters and a review of the relevant mathematics make this book instantly accessible to graduate students and researchers in the atmospheric sciences. |
chemical eric case study: The Method Method Eric Ryan, Adam Lowry, Lucas Conley, 2011-09-15 An inspiring case study for the next generation of start-ups by the unconventional founders of Method. Founded ten years ago by childhood pals Eric Ryan and Adam Lowry, Method has been making headlines and profits with a revolutionary blend of culture and commerce, style and substance. Today, Method's ecofriendly soaps, detergents, and cleaners are ubiquitous in stores, capturing valuable shelf space long dominated by the tired old products of giants P&G and Unilever. Ryan and Lowry obsess over seven principles at the heart of Method's business philosophy, including: *Kick Ass at Fast: Use small size to your advantage; by bringing innovations to market faster, you can stay out in front of larger rivals. *Inspire Advocates: Rather than getting caught up in costly battles for market share, foster deeper relationships with fewer customers in pursuit of greater wallet share. *Win on Product Experience: Beyond satisfying your customers' rational needs, design experiences for them. The Method Method is an irreverent, candid, firsthand case study. Readers will learn how today's consumers behave, how today's companies compete, and how both groups are acting together to drive profound global change. |
chemical eric case study: Hidden Costs of Energy National Research Council, Policy and Global Affairs, Board on Science, Technology, and Economic Policy, Division on Engineering and Physical Sciences, Board on Energy and Environmental Systems, Division on Earth and Life Studies, Board on Environmental Studies and Toxicology, Committee on Health, Environmental, and Other External Costs and Benefits of Energy Production and Consumption, 2010-05-26 Despite the many benefits of energy, most of which are reflected in energy market prices, the production, distribution, and use of energy causes negative effects. Many of these negative effects are not reflected in energy market prices. When market failures like this occur, there may be a case for government interventions in the form of regulations, taxes, fees, tradable permits, or other instruments that will motivate recognition of these external or hidden costs. The Hidden Costs of Energy defines and evaluates key external costs and benefits that are associated with the production, distribution, and use of energy, but are not reflected in market prices. The damage estimates presented are substantial and reflect damages from air pollution associated with electricity generation, motor vehicle transportation, and heat generation. The book also considers other effects not quantified in dollar amounts, such as damages from climate change, effects of some air pollutants such as mercury, and risks to national security. While not a comprehensive guide to policy, this analysis indicates that major initiatives to further reduce other emissions, improve energy efficiency, or shift to a cleaner electricity generating mix could substantially reduce the damages of external effects. A first step in minimizing the adverse consequences of new energy technologies is to better understand these external effects and damages. The Hidden Costs of Energy will therefore be a vital informational tool for government policy makers, scientists, and economists in even the earliest stages of research and development on energy technologies. |
chemical eric case study: Chemistry Bernadette Bensaude-Vincent, Jonathan Simon, 2008 A presentation of the history and philosophy of chemistry. It introduces the reader to various themes in the domain, and argues for a thesis: chemistry is not reducible to physics, but rather needs it own philosophy that reflects its practical engagement with the material world. |
chemical eric case study: Chemical Engineering in the Pharmaceutical Industry Mary T. am Ende, David J. am Ende, 2019-04-08 A guide to the important chemical engineering concepts for the development of new drugs, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry offers a guide to the experimental and computational methods related to drug product design and development. The second edition has been greatly expanded and covers a range of topics related to formulation design and process development of drug products. The authors review basic analytics for quantitation of drug product quality attributes, such as potency, purity, content uniformity, and dissolution, that are addressed with consideration of the applied statistics, process analytical technology, and process control. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The contributors explore technology transfer and scale-up of batch processes that are exemplified experimentally and computationally. Written for engineers working in the field, the book examines in-silico process modeling tools that streamline experimental screening approaches. In addition, the authors discuss the emerging field of continuous drug product manufacturing. This revised second edition: Contains 21 new or revised chapters, including chapters on quality by design, computational approaches for drug product modeling, process design with PAT and process control, engineering challenges and solutions Covers chemistry and engineering activities related to dosage form design, and process development, and scale-up Offers analytical methods and applied statistics that highlight drug product quality attributes as design features Presents updated and new example calculations and associated solutions Includes contributions from leading experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduation students, and professionals in the field of pharmaceutical sciences and manufacturing, Chemical Engineering in the Pharmaceutical Industry, Second Edition contains information designed to be of use from the engineer's perspective and spans information from solid to semi-solid to lyophilized drug products. |
chemical eric case study: Understanding Multiple Environmental Stresses National Research Council, Division on Earth and Life Studies, Board on Atmospheric Sciences and Climate, Committee on Earth-Atmosphere Interactions: Understanding and Responding to Multiple Environmental Stresses, 2007-04-25 The research of the last decade has demonstrated that ecosystems and human systems are influenced by multiple factors, including climate, land use, and the by-products of resource use. Understanding the net impact of a suite of simultaneously occurring environmental changes is essential for developing effective response strategies. Using case studies on drought and a wide range of atmosphere-ecosystem interactions, a workshop was held in September 2005 to gather different perspectives on multiple stress scenarios. The overarching lesson of the workshop is that society will require new and improved strategies for coping with multiple stresses and their impacts on natural socioeconomic systems. Improved communication among stakeholders; increased observations (especially at regional scales); improved model and information systems; and increased infrastructure to provide better environmental monitoring, vulnerability assessment, and response analysis are all important parts of moving toward better understanding of and response to situations involving multiple stresses. During the workshop, seven near-term opportunities for research and infrastructure that could help advance understanding of multiple stresses were also identified. |
chemical eric case study: Chemical Engineering in the Pharmaceutical Industry David J. am Ende, Mary T. am Ende, 2019-04-23 A guide to the development and manufacturing of pharmaceutical products written for professionals in the industry, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry is a practical book that highlights chemistry and chemical engineering. The book’s regulatory quality strategies target the development and manufacturing of pharmaceutically active ingredients of pharmaceutical products. The expanded second edition contains revised content with many new case studies and additional example calculations that are of interest to chemical engineers. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The active pharmaceutical ingredients book puts the focus on the chemistry, chemical engineering, and unit operations specific to development and manufacturing of the active ingredients of the pharmaceutical product. The drug substance operations section includes information on chemical reactions, mixing, distillations, extractions, crystallizations, filtration, drying, and wet and dry milling. In addition, the book includes many applications of process modeling and modern software tools that are geared toward batch-scale and continuous drug substance pharmaceutical operations. This updated second edition: Contains 30new chapters or revised chapters specific to API, covering topics including: manufacturing quality by design, computational approaches, continuous manufacturing, crystallization and final form, process safety Expanded topics of scale-up, continuous processing, applications of thermodynamics and thermodynamic modeling, filtration and drying Presents updated and expanded example calculations Includes contributions from noted experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduate students, and professionals in the field of pharmaceutical sciences and manufacturing, the second edition of Chemical Engineering in the Pharmaceutical Industryf ocuses on the development and chemical engineering as well as operations specific to the design, formulation, and manufacture of drug substance and products. |
chemical eric case study: Metachemistry Klaus Ruthenberg, 2024-08-19 Ruthenberg highlights the unique aspects of chemistry, specifically its metachemical fundamentals, which have been largely overlooked in current philosophies of science. Conventional metaphysics, derived from or focused on theoretical physics, is inadequate when applied to chemistry. The author examines and integrates historical and philosophical perspectives on important aspects of chemistry, including affinity, compositionism, emergence, synthesis/analysis, atomism/non-atomism, chemical species, chemical bond, chemical concepts, plurality, temporality/potentiality, reactivity, and underdetermination. To accomplish this, he draws on the works of notable chemists such as František Wald, Wilhelm Ostwald, Friedrich Paneth, and Hans Primas, who have contributed to the philosophical understanding of chemistry. The central conclusion of this study aligns with Immanuel Kant's viewpoint: Chemistry is a systematic art. |
chemical eric case study: Democratizing Innovation Eric Von Hippel, 2006-02-17 The process of user-centered innovation: how it can benefit both users and manufacturers and how its emergence will bring changes in business models and in public policy. Innovation is rapidly becoming democratized. Users, aided by improvements in computer and communications technology, increasingly can develop their own new products and services. These innovating users—both individuals and firms—often freely share their innovations with others, creating user-innovation communities and a rich intellectual commons. In Democratizing Innovation, Eric von Hippel looks closely at this emerging system of user-centered innovation. He explains why and when users find it profitable to develop new products and services for themselves, and why it often pays users to reveal their innovations freely for the use of all.The trend toward democratized innovation can be seen in software and information products—most notably in the free and open-source software movement—but also in physical products. Von Hippel's many examples of user innovation in action range from surgical equipment to surfboards to software security features. He shows that product and service development is concentrated among lead users, who are ahead on marketplace trends and whose innovations are often commercially attractive. Von Hippel argues that manufacturers should redesign their innovation processes and that they should systematically seek out innovations developed by users. He points to businesses—the custom semiconductor industry is one example—that have learned to assist user-innovators by providing them with toolkits for developing new products. User innovation has a positive impact on social welfare, and von Hippel proposes that government policies, including R&D subsidies and tax credits, should be realigned to eliminate biases against it. The goal of a democratized user-centered innovation system, says von Hippel, is well worth striving for. An electronic version of this book is available under a Creative Commons license. |
chemical eric case study: Insect Hydrocarbons Gary J. Blomquist, Anne-Geneviève Bagnères, 2010-02-04 A unique and critical analysis of the wealth of research conducted on the biology, biochemistry and chemical ecology of the rapidly growing field of insect cuticular hydrocarbons. Authored by leading experts in their respective fields, the twenty chapters show the complexity that has been discovered in the nature and role of hydrocarbons in entomology. Covers, in great depth, aspects of chemistry (structures, qualitative and quantitative analysis), biochemistry (biosynthesis, molecular biology, genetics, evolution), physiology, taxonomy, and ecology. Clearly presents to the reader the array of data, ideas, insights and historical disagreements that have been accumulated during the past half century. An emphasis is placed on the role of insect hydrocarbons in chemical communication, especially among the social insects. Includes the first review on the chemical synthesis of insect hydrocarbons. The material presented is a major resource for current researchers and a source of ideas for new researchers. |
chemical eric case study: Discovering the Brain National Academy of Sciences, Institute of Medicine, Sandra Ackerman, 1992-01-01 The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the Decade of the Brain by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a field guide to the brainâ€an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€and how a gut feeling actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the Decade of the Brain, with a look at medical imaging techniquesâ€what various technologies can and cannot tell usâ€and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€and many scientists as wellâ€with a helpful guide to understanding the many discoveries that are sure to be announced throughout the Decade of the Brain. |
chemical eric case study: Silent Spring Rachel Carson, 2002 The essential, cornerstone book of modern environmentalism is now offered in a handsome 40th anniversary edition which features a new Introduction by activist Terry Tempest Williams and a new Afterword by Carson biographer Linda Lear. |
chemical eric case study: Blood-Brain Barrier in Drug Discovery Li Di, Edward H. Kerns, 2015-02-02 Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can affect important improvements in one of the most significant – and most challenging – areas of drug discovery. • Written by world experts to provide practical solutions to increase brain penetration or minimize CNS side-effects • Reviews state-of-the-art in silico, in vitro, and in vivo tools to assess brain penetration and advanced CNS drug delivery strategies • Covers BBB physiology, medicinal chemistry design principles, free drug hypothesis for the BBB, and transport mechanisms including passive diffusion, uptake/efflux transporters, and receptor-mediated processes • Highlights the advances in modelling BBB pharmacokinetics and dynamics relationships (PK/PD) and physiologically-based pharmacokinetics (PBPK) • Discusses case studies of successful CNS and non-CNS drugs, lessons learned and paths to the market |
chemical eric case study: Philosophy of Chemistry Andrea Woody, Robin Findlay Hendry, Paul Needham, 2012 Philosophy of Chemistry investigates the foundational concepts and methods of chemistry, the science of the nature of substances and their transformations. This groundbreaking collection, the most thorough treatment of the philosophy of chemistry ever published, brings together philosophers, scientists and historians to map out the central topics in the field. The 33 articles address the history of the philosophy of chemistry and the philosophical importance of some central figures in the history of chemistry; the nature of chemical substances; central chemical concepts and methods, including the chemical bond, the periodic table and reaction mechanisms; and chemistry's relationship to other disciplines such as physics, molecular biology, pharmacy and chemical engineering. This volume serves as a detailed introduction for those new to the field as well as a rich source of new insights and potential research agendas for those already engaged with the philosophy of chemistry. Provides a bridge between philosophy and current scientific findings Encourages multi-disciplinary dialogue Covers theory and applications |
chemical eric case study: Soil Fertility Decline in the Tropics Alfred E. Hartemink, 2003 Wide coverage of soils and perennial cropping systems in the tropicsSynthesis of decades of researchChallenges assumptions on the benefits of plantations for soil fertilityIt is generally assumed that soil fertility decline is widespread in the tropics and that this is largely associated with annual cropping and subsistence farming. In contrast, perennial plant cover (as in plantation agriculture) provides better protection for the soil.This book reviews these concepts, focusing on soil chemical changes under different land-use systems in the tropics. These include perennial crops, annual crops and forest plantations. Two case studies, on sisal plantations in Tanzania and sugar cane in Papua New Guinea, are presented for detailed analysis. The author demonstrates that soil fertility decline is also a problem on plantations. |
chemical eric case study: Teaching Innovation in University Education: Case Studies and Main Practices Saura, Jose Ramon, 2022-06-17 In the last decade, the development of new technologies has made innovation a fundamental pillar of education. Teaching innovation includes the evolution of both teaching and learning models to drive improvements in educational methodologies. Teaching innovation is a pioneer in the understanding and comprehension of the different teaching methodologies and models developed in the academic area. Teaching innovation is a process that seeks validation in the academic and teaching communities at universities in order to promote the improvement and its practices and uses in the future characterized by digital development and data-based methods. Teaching Innovation in University Education: Case Studies and Main Practices features the major practices and case studies of teaching innovation developed in recent years at universities. It is a source on study cases focused on teaching innovation methodologies as well as on the identification of new technologies that will help the development of initiatives and practices focused on teaching innovation at higher education institutions. Covering topics such as didactic strategics, service learning, and technology-based gamification, this premier reference source is an indispensable resource for pre-service teachers, lecturers, students, faculty, administrators, libraries, entrepreneurs, researchers, and academicians. |
chemical eric case study: Managing Hazardous Reactions and Compounds in Process Chemistry Jaan A. Pesti, Ahmed F. Abdel-Magid, 2015-07-31 There is always potential for hazards during chemical reactions that can lead to accidents resulting in loss of time, equipment, products and harm to people. The hazards may result from uncontrolled exothermic reactions or secondary exothermic reactions such as decomposition of a reactant, reagent or product. Hazards may also occur from impurities or metal residues that can catalyze undesired exothermic reactions or decompositions. Many organic reactants, reagents, products as well as solvents have varying degrees of toxic effects and/or fire hazard if not handled properly. Improperly treated waste may also be a source of many hazards. Managing all these hazards effectively is very important for carrying out reactions safely, particularly on large scale. To achieve this goal, chemists and engineers need a clear understanding of the thermal characteristics of chemical reactions derived from accurate quantitative measurements and clear scientific knowledge of reaction mechanisms. They also need to build an expertise on handling toxic and flammable materials and proper procedures to waste treatment and disposal. To address these objectives, this book covers many topics on management of potential hazards in the chemical and pharmaceutical industries. The topics range from classical batch reactions to the latest innovative applications of continuous processes and flow chemistry. The applications range in scale from bench to manufacturing. The book contains 16 chapters on different aspects of managing chemical reaction hazards contributed by a group of internationally renowned leading chemical safety and hazard management experts. Their contributions make this book a valuable addition to the scientific literature |
chemical eric case study: Environmental Forensics R E Hester, R M Harrison, 2008-06-27 'Environmental forensics' is a combination of analytical and environmental chemistry, which is useful in the court room context. It therefore involves field analytical studies and both data interpretation and modelling connected with the attribution of pollution events to their causes. Recent decades have seen a burgeoning of legislation designed to protect the environment and, as the costs of environmental damage and clean-up are considerable, not only are there prosecutions by regulatory agencies, but the courts are also used as a means of adjudication of civil damage claims relating to environmental causes or environmental degradation. As a result is the increasing number of prosecutions of companies who have breached regulations for environmental protection and in civil claims relating to harm caused by excessive pollutant releases to the environment. Such cases can become extremely protracted as expert witnesses provide their sometimes conflicting interpretations of environmental measurement data and their meaning. It is in this context that environmental forensics is developing as a specialism, leading to greater formalisation of investigative methods which should lead to more definitive findings and less scope for experts to disagree. Now a significant subject in its own right, at least one journal devoted to the field and a number of degree courses have sprung up. As a result of the topicality and rapid growth of the subject area, is the publication of this book - the 26th volume in the highly acclaimed Issues in Environmental Science and Technology Series. This volume contains authoritative articles by a number of the leading practitioners across the globe in the environmental forensics field and aims to cover some of the main techniques and areas to which environmental forensics are being applied. The content is comprehensive and describes a number of the key areas within environmental forensics - topics covered by the authors include: - Source identification issues - Microbial techniques - Metal contamination and methods of assigning liability - The use of isotopes to determine sources and their applications - Molecular biological methods - Hydrocarbon fingerprinting techniques - Oil chemistry and key compound identification - The emerging role of environmental forensics in groundwater pollution Additionally, the volume considers specific pollutants and long-lived pollutants of groundwater such as halocarbons which have presented particular problems and which are described in some depth, as well as the way in which chemical degradation processes can lead to compositional changes which provide valuable information. The book provides a comprehensive overview of many of the key areas of environmental forensics written by some of the leading experts in the field. It will be both of specialist use to those seeking expert insights into the field and its capabilities as well as of more general interest to those involved in both environmental analytical science and environmental law. |
chemical eric case study: The Philosophy of Chemistry Jean-Pierre Llored, 2014-09-26 This volume connects chemistry and philosophy in order to face questions raised by chemistry in our present world. The idea is first to develop a kind of philosophy of chemistry which is deeply rooted in the exploration of chemical activities. We thus work in close contact with chemists (technicians, engineers, researchers, and teachers). Following this line of reasoning, the first part of the book encourages current chemists to describe their workaday practices while insisting on the importance of attending to methodological, metrological, philosophical, and epistemological questions related to their activities. It deals with sustainable chemistry, chemical metrology, nanochemistry, and biochemistry, among other crucial topics. In doing so, those chemists invite historians and philosophers to provide ideas for future developments. In a nutshell, this part is a call for forthcoming collaborations focused on instruments and methods, that is on ways of doing chemistry. The second part of the book illustrates the multifarious ways to study chemistry and even proposes new approaches to doing so. Each approach is interesting and incomplete but the emergent whole is richer than any of its components. Analytical work needs socio-historical expertise as well as many other approaches in order to keep on investigating chemistry to greater and greater depth. This heterogeneity provides a wide set of methodological perspectives not only about current chemical practices but also about the ways to explore them philosophically. Each approach is a resource to study chemistry and to reflect upon what doing philosophy of science can mean. In the last part of the volume, philosophers and chemists propose new concepts or reshape older ones in order to think about chemistry. The act of conceptualization itself is queried as well as the relationships between concepts and chemical activities. Prefaced by Nobel Laureate in Chemistry, Roald Hoffmann, and by the President of the International Society for the Philosophy of Chemistry, Rom Harré, this volume is a plea for the emergence of a collective cleverness and aims to foster inventiveness. |
chemical eric case study: 31st European Symposium on Computer Aided Process Engineering Metin Türkay, Rafiqul Gani, 2021-07-22 The 31st European Symposium on Computer Aided Process Engineering: ESCAPE-31, Volume 50 contains the papers presented at the 31st European Symposium of Computer Aided Process Engineering (ESCAPE) event held in Istanbul, Turkey. It is a valuable resource for chemical engineers, chemical process engineers, researchers in industry and academia, students and consultants in the chemical industries. - Presents findings and discussions from the 31st European Symposium of Computer Aided Process Engineering (ESCAPE) event |
chemical eric case study: Anxiety and the Equation Eric Johnson, 2018-10-23 A man and his equation: the anxiety-plagued nineteenth-century physicist who contributed significantly to our understanding of the second law of thermodynamics. Ludwig Boltzmann's grave in Vienna's Central Cemetery bears a cryptic epitaph: S = k log W. This equation was Boltzmann's great discovery, and it contributed significantly to our understanding of the second law of thermodynamics. In Anxiety and the Equation, Eric Johnson tells the story of a man and his equation: the anxiety-plagued nineteenth-century physicist who did his most important work as he struggled with mental illness. Johnson explains that “S” in Boltzmann's equation refers to entropy, and that entropy is the central quantity in the second law of thermodynamics. The second law is always on, running in the background of our lives, providing a way to differentiate between past and future. We know that the future will be a state of higher entropy than the past, and we have Boltzmann to thank for discovering the equation that underlies that fundamental trend. Johnson, accessibly and engagingly, reassembles Boltzmann's equation from its various components and presents episodes from Boltzmann's life—beginning at the end, with “Boltzmann Kills Himself” and “Boltzmann Is Buried (Not Once, But Twice).” Johnson explains the second law in simple terms, introduces key concepts through thought experiments, and explores Boltzmann's work. He argues that Boltzmann, diagnosed by his contemporaries as neurasthenic, suffered from an anxiety disorder. He was, says Johnson, a man of reason who suffered from irrational concerns about his work, worrying especially about opposition from the scientific establishment of the day. Johnson's clear and concise explanations will acquaint the nonspecialist reader with such seemingly esoteric concepts as microstates, macrostates, fluctuations, the distribution of energy, log functions, and equilibrium. He describes Boltzmann's relationships with other scientists, including Max Planck and Henri Poincaré, and, finally, imagines “an alternative ending,” in which Boltzmann lived on and died of natural causes. |
chemical eric case study: Forging a Poison Prevention and Control System Institute of Medicine, Board on Health Promotion and Disease Prevention, Committee on Poison Prevention and Control, 2004-09-16 Poisoning is a far more serious health problem in the U.S. than has generally been recognized. It is estimated that more than 4 million poisoning episodes occur annually, with approximately 300,000 cases leading to hospitalization. The field of poison prevention provides some of the most celebrated examples of successful public health interventions, yet surprisingly the current poison control system is little more than a loose network of poison control centers, poorly integrated into the larger spheres of public health. To increase their effectiveness, efforts to reduce poisoning need to be linked to a national agenda for public health promotion and injury prevention. Forging a Poison Prevention and Control System recommends a future poison control system with a strong public health infrastructure, a national system of regional poison control centers, federal funding to support core poison control activities, and a national poison information system to track major poisoning epidemics and possible acts of bioterrorism. This framework provides a complete system that could offer the best poison prevention and patient care services to meet the needs of the nation in the 21st century. |
chemical eric case study: Chemistry: The Impure Science Bernadette Bensaude-vincent, Jonathan Simon, 2008-10-16 This book uses history to introduce central issues in the philosophy of chemistry. Mobilizing the theme of impurity, it explores the tradition of chemistry's negative image. It then argues for the positive philosophical value of chemistry, reflecting its characteristic practical engagement with the material world. The book concludes with some ethical reflections concerning chemistry's orientations in the twenty-first century.The authors have previously both offered significant contributions to the history and philosophy of chemistry./a |
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May 12, 2025 · A chemical reaction is a process in which one or more substances, the reactants, are converted to one or more different substances, the products. Substances are either …
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Apr 24, 2025 · Most of the materials that occur on Earth, such as wood, coal, minerals, or air, are mixtures of many different and distinct chemical substances. Each pure chemical substance …
Periodic table | Definition, Elements, Groups, Charges, Trends,
May 10, 2025 · The periodic table is a tabular array of the chemical elements organized by atomic number, from the element with the lowest atomic number, hydrogen, to the element with the …
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Apr 29, 2025 · A chemical element is any substance that cannot be decomposed into simpler substances by ordinary chemical processes. Elements are the fundamental materials of which …
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May 9, 2025 · chemical bonding in benzene Benzene is the smallest of the organic aromatic hydrocarbons. It contains sigma bonds (represented by lines) and regions of high-pi electron …
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