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| bioconjugate chemistry impact factor: Bioconjugate Techniques Greg T. Hermanson, 2010-07-26 Bioconjugate Techniques, 2nd Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions with details on hundreds of commercially available reagents and the use of these reagents for modifying or cross linking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers. A one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab Step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates More than 600 figures that visually describe the complex reactions associated with the synthesis of bioconjugates Includes entirely new chapters on the latest areas in the field of bioconjugation as follows: Microparticles and nanoparticlesSilane coupling agentsDendrimers and dendronsChemoselective ligationQuantum dotsLanthanide chelatesCyanine dyesDiscrete PEG compoundsBuckyballs,fullerenes, and carbon nanotubesMass tags and isotope tagsBioconjugation in the study of protein interactions |
| bioconjugate chemistry impact factor: Journal American Chemical Society, 2004 |
| bioconjugate chemistry impact factor: Issues in Specialized Chemical and Chemistry Topics: 2012 Edition , 2013-01-10 Issues in Specialized Chemical and Chemistry Topics: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Chemical Theory and Computation. The editors have built Issues in Specialized Chemical and Chemistry Topics: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Chemical Theory and Computation in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Specialized Chemical and Chemistry Topics: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| bioconjugate chemistry impact factor: Multivalency Jurriaan Huskens, Leonard J. Prins, Rainer Haag, Bart Jan Ravoo, 2018-02-05 Connects fundamental knowledge of multivalent interactions with current practice and state-of-the-art applications Multivalency is a widespread phenomenon, with applications spanning supramolecular chemistry, materials chemistry, pharmaceutical chemistry and biochemistry. This advanced textbook provides students and junior scientists with an excellent introduction to the fundamentals of multivalent interactions, whilst expanding the knowledge of experienced researchers in the field. Multivalency: Concepts, Research & Applications is divided into three parts. Part one provides background knowledge on various aspects of multivalency and cooperativity and presents practical methods for their study. Fundamental aspects such as thermodynamics, kinetics and the principle of effective molarity are described, and characterisation methods, experimental methodologies and data treatment methods are also discussed. Parts two and three provide an overview of current systems in which multivalency plays an important role in chemistry and biology, with a focus on the design rules, underlying chemistry and the fundamental principles of multivalency. The systems covered range from chemical/materials-based ones such as dendrimers and sensors, to biological systems including cell recognition and protein binding. Examples and case studies from biochemistry/bioorganic chemistry as well as synthetic systems feature throughout the book. Introduces students and young scientists to the field of multivalent interactions and assists experienced researchers utilising the methodologies in their work Features examples and case studies from biochemistry/bioorganic chemistry, as well as synthetic systems throughout the book Edited by leading experts in the field with contributions from established scientists Multivalency: Concepts, Research & Applications is recommended for graduate students and junior scientists in supramolecular chemistry and related fields, looking for an introduction to multivalent interactions. It is also highly useful to experienced academics and scientists in industry working on research relating to multivalent and cooperative systems in supramolecular chemistry, organic chemistry, pharmaceutical chemistry, chemical biology, biochemistry, materials science and nanotechnology. |
| bioconjugate chemistry impact factor: The Future of U.S. Chemistry Research National Research Council, Division on Earth and Life Studies, Board on Chemical Sciences and Technology, Committee on Benchmarking the Research Competitiveness of the United States in Chemistry, 2007-06-08 Chemistry plays a key role in conquering diseases, solving energy problems, addressing environmental problems, providing the discoveries that lead to new industries, and developing new materials and technologies for national defense and homeland security. However, the field is currently facing a crucial time of change and is struggling to position itself to meet the needs of the future as it expands beyond its traditional core toward areas related to biology, materials science, and nanotechnology. At the request of the National Science Foundation and the U.S. Department of Energy, the National Research Council conducted an in-depth benchmarking analysis to gauge the current standing of the U.S. chemistry field in the world. The Future of U.S. Chemistry Research: Benchmarks and Challenges highlights the main findings of the benchmarking exercise. |
| bioconjugate chemistry impact factor: Science John Michels (Journalist), 2006 A weekly record of scientific progress. |
| bioconjugate chemistry impact factor: Chemical Ligation Luca D. D'Andrea, Alessandra Romanelli, 2017-04-03 Presenting a wide array of information on chemical ligation – one of the more powerful tools for protein and peptide synthesis – this book helps readers understand key methodologies and applications that protein therapeutic synthesis, drug discovery, and molecular imaging. • Moves from fundamental to applied aspects, so that novice readers can follow the entire book and apply these reactions in the lab • Presents a wide array of information on chemical ligation reactions, otherwise scattered across the literature, into one source • Features comprehensive and multidisciplinary coverage that goes from basics to advanced topics • Helps researchers choose the right chemical ligation technique for their needs |
| bioconjugate chemistry impact factor: Maleates—Advances in Research and Application: 2013 Edition , 2013-06-21 Maleates—Advances in Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about ZZZAdditional Research in a concise format. The editors have built Maleates—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Maleates—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| bioconjugate chemistry impact factor: Antibody-Drug Conjugates Kenneth J. Olivier, Jr., Sara A. Hurvitz, 2016-11-14 Providing practical and proven solutions for antibody-drug conjugate (ADC) drug discovery success in oncology, this book helps readers improve the drug safety and therapeutic efficacy of ADCs to kill targeted tumor cells. • Discusses the basics, drug delivery strategies, pharmacology and toxicology, and regulatory approval strategies • Covers the conduct and design of oncology clinical trials and the use of ADCs for tumor imaging • Includes case studies of ADCs in oncology drug development • Features contributions from highly-regarded experts on the frontlines of ADC research and development |
| bioconjugate chemistry impact factor: Issues in Specialized Chemical and Chemistry Topics: 2011 Edition , 2012-01-09 Issues in Specialized Chemical and Chemistry Topics: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Specialized Chemical and Chemistry Topics. The editors have built Issues in Specialized Chemical and Chemistry Topics: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Specialized Chemical and Chemistry Topics in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Specialized Chemical and Chemistry Topics: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| bioconjugate chemistry impact factor: List of journals indexed in Index medicus , 2004 |
| bioconjugate chemistry impact factor: Handbook of Polymers for Pharmaceutical Technologies, Structure and Chemistry Vijay Kumar Thakur, Manju Kumari Thakur, 2015-06-19 Polymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life. Polymers are either directly available in nature or are chemically synthesized and used depending upon the targeted applications.Advances in polymer science and the introduction of new polymers have resulted in the significant development of polymers with unique properties. Different kinds of polymers have been and will be one of the key in several applications in many of the advanced pharmaceutical research being carried out over the globe. This 4-partset of books contains precisely referenced chapters, emphasizing different kinds of polymers with basic fundamentals and practicality for application in diverse pharmaceutical technologies. The volumes aim at explaining basics of polymers based materials from different resources and their chemistry along with practical applications which present a future direction in the pharmaceutical industry. Each volume offer deep insight into the subject being treated. Volume 1: Structure and Chemistry Volume 2: Processing and Applications Volume 3: Biodegradable Polymers Volume 4: Bioactive and Compatible Synthetic/Hybrid Polymers |
| bioconjugate chemistry impact factor: Cell and Material Interface Nihal Engin Vrana, 2018-09-03 A significant portion of biomedical applications necessitates the establishment of an interface between the cells of the patient and the components of the device. In many cases, such as in implants and engineered tissues, the interaction of the cells with the biomaterial is one of the main determinants of the success of the system. Cell and Material Interface: Advances in Tissue Engineering, Biosensor, Implant, and Imaging Technologies explores this interaction and its control at length scales ranging from the nano to the macro. Featuring contributions from leading molecular biologists, chemists, and material scientists, this authoritative reference: Presents practical examples of cell and material interface-based applications Reflects the interdisciplinary nature of bioengineering, covering topics such as biosensing, immunology, and controlled delivery Explains the role of the cell and material interface in the context of cardiac and skin tissue engineering, nanoparticles, natural polymers, and more Cell and Material Interface: Advances in Tissue Engineering, Biosensor, Implant, and Imaging Technologies addresses concepts essential to biomaterial production methods and cell and material interactions. The book provides a solid starting point for elucidating and exploiting the different aspects of cellular interactions with materials for biomedical engineering. |
| bioconjugate chemistry impact factor: Handbook of Nanomaterials for Cancer Theranostics Joao Conde, 2018-06-27 Handbook of Nanomaterials for Cancer Theranostics focuses on recent developments in advanced theranostic nanomedicines from a chemical and biological perspective where the advantages of theranostics are achieved by combining multiple components. The authors explore the pros and cons of theranostic nanomaterials developed in cancer research in the last 15 years, with the different strategies compared and scrutinized. In addition, the book explores how nanomaterials may overcome the regulatory hurdles facing theranostic nanomedicines. This is an important research reference for postgraduates and researchers in nanomedicine and cancer research who want to learn more on how nanomaterials can help create more effective cancer treatments. - Highlights the development of smart theranostic nanomaterials to tackle biomedical problems in cancer therapy and diagnostics - Explores the regulatory hurdles facing theranostic nanomedicine - Discusses how the use of nanomaterials can help create more effective cancer treatments |
| bioconjugate chemistry impact factor: Making Sense of Journals in the Physical Sciences Tony Stankus, 1992 The author lays out the patterns of subject specialization within chemistry and physics in non-technical language, emphasizing the often colourful people and events that influenced the founding of new areas of research and their journals. |
| bioconjugate chemistry impact factor: Nanobiosensors and Nanobioanalyses Mun'delanji C. Vestergaard, Kagan Kerman, I-Ming Hsing, Eiichi Tamiya, 2015-03-18 This book provides a comprehensive review of established, cutting-edge, and future trends in the exponentially growing field of nanomaterials and their applications in biosensors and bioanalyses. Part I focuses on the key principles and transduction approaches, reviewing the timeline featuring the important historical milestones in the development and application of nanomaterials in biosensors and bioanalyses. Part II reviews various architectures used in nanobiosensing designs focusing on nanowires, one- and two-dimensional nanostructures, and plasmonic nanobiosensors with interferometric reflectance imaging. Commonly used nanomaterials, functionalization of the nanomaterials, and development of nanobioelectronics are discussed in detail in Part III with examples from screen-printed electrodes, nanocarbon films, and semiconductor quantum dots. Part IV reviews the current applications of carbon nanotubes, nanoneedles, plasmonic sensors, electrochemical scanning microscopes, and field-effect transistors with the future outlook for emerging technologies. Attention is also given to potential challenges, in particular, of taking these technologies at the point-of-need. The book concludes by providing a condensed summary of the contents, with emphasis on future directions. Nanomaterials have become an essential part of biosensors and bioanalyses in the detection and monitoring of medical, pharmaceutical, and environmental conditions, from cancer to chemical warfare agents. This book, with its distinguished editors and international team of expert contributors, will be an essential guide for all those involved in the research, design, development, and application of nanomaterials in biosensors and bioanalyses. |
| bioconjugate chemistry impact factor: The Textbook of Nanoneuroscience and Nanoneurosurgery Babak Kateb, |
| bioconjugate chemistry impact factor: ACS Style Guide Anne M. Coghill, Lorrin R. Garson, 2006 In the time since the second edition of The ACS Style Guide was published, the rapid growth of electronic communication has dramatically changed the scientific, technical, and medical (STM) publication world. This dynamic mode of dissemination is enabling scientists, engineers, and medicalpractitioners all over the world to obtain and transmit information quickly and easily. An essential constant in this changing environment is the requirement that information remain accurate, clear, unambiguous, and ethically sound.This extensive revision of The ACS Style Guide thoroughly examines electronic tools now available to assist STM writers in preparing manuscripts and communicating with publishers. Valuable updates include discussions of markup languages, citation of electronic sources, online submission ofmanuscripts, and preparation of figures, tables, and structures. In keeping current with the changing environment, this edition also contains references to many resources on the internet.With this wealth of new information, The ACS Style Guide's Third Edition continues its long tradition of providing invaluable insight on ethics in scientific communication, the editorial process, copyright, conventions in chemistry, grammar, punctuation, spelling, and writing style for any STMauthor, reviewer, or editor. The Third Edition is the definitive source for all information needed to write, review, submit, and edit scholarly and scientific manuscripts. |
| bioconjugate chemistry impact factor: A Short History of Chemistry James Riddick Partington, 1951 |
| bioconjugate chemistry impact factor: Index Medicus , 2004 Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings. |
| bioconjugate chemistry impact factor: Gastrointestinal Hormones—Advances in Research and Application: 2012 Edition , 2012-12-26 Gastrointestinal Hormones—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Gastrointestinal Hormones. The editors have built Gastrointestinal Hormones—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Gastrointestinal Hormones in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Gastrointestinal Hormones—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| bioconjugate chemistry impact factor: WTEC Panel Report on Tissue Engineering Research Larry V. McIntire, 2003-02-04 WTEC Panel on Tissue Engineering Research is a comparative review of tissue engineering research and development activities in the United States, Japan, and Western Europe conducted by a panel of leading U.S. experts in the field. This book covers biomaterials, cells, biomolecules, non-medical applications, engineering design, informatics, and legal and regulatory issues associated with tissue engineering research and applications. This document will serve as a basis for continued dialogue within nations' tissue engineering research and development community and with other important stakeholders, providing guidance for future programs. This text highlights the necessity for providing continued and enhanced resources to further the progress in tissue engineering, harness developments, and maintain scientific and economic leadership. |
| bioconjugate chemistry impact factor: Novel Platforms for Drug Delivery Applications Sangita Das, Sabu Thomas, Partha Pratim Das, 2022-11-08 Novel Platforms for Drug Delivery Applications covers diverse aspects in the design, synthesis and characterization of novel drug delivery platforms and devices. This book comprehensively details the development, application and performance of various novel molecular frameworks as potent drug delivery vehicles. Chapters cover a range of materials and molecular platforms for drug delivery, from hydrogels, nanocarriers and metal-organic-frameworks, to ?-cyclodextrin and polyphosphazene. Each chapter discusses the benefits and limitations of each drug delivery system, as well as toxicological and safety implications. This book offers an interdisciplinary approach to this fast-moving topic, bridging the disciplines of materials science and pharmacology. - Provides an up-to-date single resource on novel drug delivery platforms, a rapidly evolving field of research - Covers a broad range of materials, systems and release mechanisms, including in vivo and in vitro studies - Describes the synthesis, properties, formulation and application of various novel drug delivery systems |
| bioconjugate chemistry impact factor: CPP, Cell-Penetrating Peptides Ülo Langel, 2023-10-18 In this book, a summary and update of the most important areas of cell-penetrating peptides (CPP) research are presented, while raising relevant questions for further development. The CPP sequences are presented and discussed throughout the book. The methods for testing CPP mechanisms are discussed in detail. Various approaches for the testing of endocytotic pathways of CPP uptake are also described. Different CPP uptake experiments are compared since it is becoming clear that it is often best to apply several methods in a complementary manner in order to most comprehensively evaluate CPP uptake mechanisms due to the complexity of these processes. A brief summary of functionality issues of CPPs, both in vitro and in vivo, is discussed. Therapeutic potential of CPPs and commercial developments are discussed. The present, second edition of this book is the updated and expanded version of the first edition, published in 2019. The development of the field of cell-penetrating peptides in these five years has been obvious and exciting. This second edition of the book has been partly reorganized and comprehensively expanded with the exciting research in 2019-2023. Around 2500 novel scientific articles have become available, most of them are reviewed in the second edition. Additional rapidly growing areas of high impact presented in this second edition are therapeutic developments (Chapter 16) and delivery of oligonucleotides and proteins/peptides (Chapters 5 and 6) including novel reports on genome editing with CPP assistance. Also, several additional examples are available now on clinical trials using CPPs (Chapter 15). The book is written for researchers and students in the field. |
| bioconjugate chemistry impact factor: Organisch-chemische Methoden Daniel Krois, 2016-11-26 Das Buch erläutert synthetische und analytische Methoden der Organischen Chemie, die für Anwendung und Forschung in Biochemie, Molekularbiologie und Medizinischer Chemie eingesetzt werden. Es ist als Lehrbuch im Masterstudium der Chemie, aber auch biologischer und medizinisch-chemischer Fächer gedacht. Es eignet sich zudem wegen der umfangreichen Literaturzitate als Monographie für Anwender im Forschungslabor. |
| bioconjugate chemistry impact factor: Parvoviruses Jonathan Kerr, Susan Cotmore, Marshall E Bloom, 2005-11-25 This comprehensive reference work brings together for the first time information on every aspect of the parvoviruses in a single volume. It presents the new system of parvovirus classification, as agreed by the International Committee for the Taxonomy of Viruses (ICTV), and includes cutting edge information on the virology, molecular and cellular biology, immunology and clinical manifestations of infection with each known and proposed member of the family Parvoviridae. The book also describes the rapidly expanding basic and clinical science which underpins gene therapy applications using helper-dependent and helper-independent parvoviruses. The respected editorial group has drawn together renowned contributors from around the world to produce what will undoubtedly become the standard reference on the subject. It is essential reading for clinical or research virologists and microbiologists, infectious disease specialists, and public health specialists and laboratories. |
| bioconjugate chemistry impact factor: Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives Jesús Fernández Lucas, María-José Camarasa Rius, 2019-04-29 A review of innovative tools for creative nucleic acid chemists that open the door to novel probes and therapeutic agents Nucleic acids continue to gain importance as novel diagnostic and therapeutic agents. With contributions from noted scientists and scholars, Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives is a practical reference that includes a wide range of approaches for the synthesis of designer nucleic acids and their derivatives. The book covers enzymatic (including chemo-enzymatic) methods, with a focus on the synthesis and incorporation of modified nucleosides. The authors also offer a review of innovative approaches for the non-enzymatic chemical synthesis of nucleic acids and their analogs and derivatives, highlighting especially challenging species. The book offers a concise review of the methods that prepare novel and heavily modified polynucleotides in sufficient amount and purity for most clinical and research applications. This important book: -Presents a timely and topical guide to the synthesis of designer nucleic acids and their derivatives -Addresses the growing market for nucleotide-derived pharmaceuticals used as anti-infectives and chemotherapeutic agents, as well as fungicides and other agrochemicals. -Covers novel methods and the most recent trends in the field -Contains contributions from an international panel of noted scientistics Written for biochemists, medicinal chemists, natural products chemists, organic chemists, and biotechnologists, Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives is a practice-oriented guide that reviews innovative methods for the enzymatic as well as non-enzymatic synthesis of nucleic acid species. |
| bioconjugate chemistry impact factor: Fungi Kevin Kavanagh, 2011-08-04 Fungi: Biology and Applications, Second Edition provides a comprehensive treatment of fungi, covering biochemistry, genetics and the medical and economic significance of these organisms at introductory level. With no prior knowledge of the subject assumed, the opening chapters offer a broad overview of the basics of fungal biology, in particular the physiology and genetics of fungi and also a new chapter on the application of genomics to fungi. Later chapters move on to include more detailed coverage of topics such as antibiotic and chemical commodities from fungi, new chapters on biotechnological use of fungal enzymes and fungal proteomics, and fungal diseases of humans, antifungal agents for use in human therapy and fungal pathogens of plants. |
| bioconjugate chemistry impact factor: Advances in Immunology , 2016-05-25 Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. - Contains contributions from leading authorities - Includes a wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities - Informs and updates on all the latest developments in the field of immunology |
| bioconjugate chemistry impact factor: Diamino Amino Acids—Advances in Research and Application: 2013 Edition , 2013-06-21 Diamino Amino Acids—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Citrulline. The editors have built Diamino Amino Acids—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Citrulline in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Diamino Amino Acids—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| bioconjugate chemistry impact factor: Liposomal Encapsulation in Food Science and Technology C. Anandharamakrishnan, Sayantani Dutta, 2022-09-30 Liposomal Encapsulation in Food Science and Technology provides all the possible applications of liposomes in food and allied systems, along with recent advances made in these fields. This helps researchers in food science and technology, as well as those in interdisciplinary fields, better explore the opportunities that liposomal encapsulation offers. Among other topics, the book covers formulation and characterization of liposome, liposome mediated encapsulation of antimicrobials and probiotics, liposome-assisted delivery of enzymes and proteins, and liposome for delivery of dietary nutrients and nutraceuticals, etc. This approach facilitates building better dedicated or tandem approaches in respective fields for process/product development. Written by an international team of contributors, the book will aid academicians in developing more industry useful tools/techniques/products. - Brings a broader overview of different modules of liposomal encapsulation of bioactive food supplements - Provides all the possible applications of liposomes in food and allied systems, along with recent advances made in these fields - Includes chemical, physical, medical and stability related chapters |
| bioconjugate chemistry impact factor: Analytical Characterization of Biotherapeutics Jennie R. Lill, Wendy Sandoval, 2017-08-14 The definitive guide to the myriad analytical techniques available to scientists involved in biotherapeutics research Analytical Characterization of Biotherapeutics covers all current and emerging analytical tools and techniques used for the characterization of therapeutic proteins and antigen reagents. From basic recombinant antigen and antibody characterization, to complex analyses for increasingly complex molecular designs, the book explores the history of the analysis techniques and offers valuable insights into the most important emerging analytical solutions. In addition, it frames critical questions warranting attention in the design and delivery of a therapeutic protein, exposes analytical challenges that may occur when characterizing these molecules, and presents a number of tested solutions. The first single-volume guide of its kind, Analytical Characterization of Biotherapeutics brings together contributions from scientists at the leading edge of biotherapeutics research and manufacturing. Key topics covered in-depth include the structural characterization of recombinant proteins and antibodies, antibody de novo sequencing, characterization of antibody drug conjugates, characterization of bi-specific or other hybrid molecules, characterization of manufacturing host-cell contaminant proteins, analytical tools for biologics molecular assessment, and more. Each chapter is written by a recognized expert or experts in their field who discuss current and cutting edge approaches to fully characterizing biotherapeutic proteins and antigen reagents Covers the full range of characterization strategies for large molecule based therapeutics Provides an up-to-date account of the latest approaches used for large molecule characterization Chapters cover the background needed to understand the challenges at hand, solutions to characterize these large molecules, and a summary of emerging options for analytical characterization Analytical Characterization of Biotherapeutics is an up-to-date resource for analytical scientists, biologists, and mass spectrometrists involved in the analysis of biomolecules, as well as scientists employed in the pharmaceuticals and biotechnology industries. Graduate students in biology and analytical science, and their instructors will find it to be fascinating and instructive supplementary reading. |
| bioconjugate chemistry impact factor: The Evolution from Protein Chemistry to Proteomics Roger L. Lundblad, 2005-10-14 Largely driven by major improvements in the analytical capability of mass spectrometry, proteomics is being applied to broader areas of experimental biology, ranging from oncology research to plant biology to environmental health. However, while it has already eclipsed solution protein chemistry as a discipline, it is still essentially an extension |
| bioconjugate chemistry impact factor: The Sugar Code Hans-Joachim Gabius, 2011-09-19 A reader friendly overview of the structure and functional relevance of natural glycosylation and its cognate proteins (lectins), this book is also one of the few books to cover their role in health and disease. Edited by one of the pioneering experts in the field and written by a team of renowned researchers this resource is a perfect introduction for all students in life and medical sciences, biochemistry, chemistry and pharmacy. Website: WWW.WILEY-VCH.DE/HOME/THESUGARCODE |
| bioconjugate chemistry impact factor: Acute-Phase Proteins—Advances in Research and Application: 2013 Edition , 2013-06-21 Acute-Phase Proteins—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about C-Reactive Protein. The editors have built Acute-Phase Proteins—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about C-Reactive Protein in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Acute-Phase Proteins—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| bioconjugate chemistry impact factor: CPP, Cell-Penetrating Peptides Ülo Langel, 2019-06-03 In this book, a summary and update of the most important areas of CPP research are presented, whilst raising relevant questions for further development. The CPP sequences are presented and discussed throughout the book. The methods for testing CPP mechanisms are discussed in detail. Various approaches for the testing of endocytotic pathways of CPP uptake are also described. Different CPP uptake experiments are compared since it is becoming clear that it is often best to apply several methods in a complementary manner in order to most comprehensively evaluate CPP uptake mechanisms due to the complexity of these processes. A brief summary of functionality issues of CPPs, both in vitro and in vivo are discussed. Therapeutic potential of CPPs and commercial developments are discussed. The monograph is written for researchers and students in the field. |
| bioconjugate chemistry impact factor: Transforming Glycoscience National Research Council, Division on Earth and Life Studies, Board on Life Sciences, Board on Chemical Sciences and Technology, Committee on Assessing the Importance and Impact of Glycomics and Glycosciences, 2012-10-23 A new focus on glycoscience, a field that explores the structures and functions of sugars, promises great advances in areas as diverse as medicine, energy generation, and materials science, this report finds. Glycans-also known as carbohydrates, saccharides, or simply as sugars-play central roles in many biological processes and have properties useful in an array of applications. However, glycans have received little attention from the research community due to a lack of tools to probe their often complex structures and properties. Transforming Glycoscience: A Roadmap for the Future presents a roadmap for transforming glycoscience from a field dominated by specialists to a widely studied and integrated discipline, which could lead to a more complete understanding of glycans and help solve key challenges in diverse fields. |
| bioconjugate chemistry impact factor: Handbook of Composites from Renewable Materials, Structure and Chemistry Vijay Kumar Thakur, Manju Kumari Thakur, Michael R. Kessler, 2017-03-08 This unique multidisciplinary 8-volume set focuses on the emerging issues concerning synthesis, characterization, design, manufacturing and various other aspects of composite materials from renewable materials and provides a shared platform for both researcher and industry. The Handbook of Composites from Renewable Materials comprises a set of 8 individual volumes that brings an interdisciplinary perspective to accomplish a more detailed understanding of the interplay between the synthesis, structure, characterization, processing, applications and performance of these advanced materials. The Handbook comprises 169 chapters from world renowned experts covering a multitude of natural polymers/ reinforcement/ fillers and biodegradable materials. Volume 1 is solely focused on the Structure and Chemistry of renewable materials. Some of the important topics include but not limited to: carbon fibers from sustainable resources; polylactic acid composites and composite foams based on natural fibres; composites materials from other than cellulosic resources; microcrystalline cellulose and related polymer composites; tannin-based foam; renewable feedstock vanillin derived polymer and composites; silk biocomposites; bioderived adhesives and matrix polymers; biomass-based formaldehyde-free bioresin; isolation and characterization of water soluble polysaccharide; biobased fillers; keratin-based materials in biotechnology; structure of proteins adsorbed onto bioactive glasses for sustainable composite; effect of filler properties on the antioxidant response of starch composites; composite of chitosan and its derivate; magnetic biochar from discarded agricultural biomass; biodegradable polymers for protein and peptide conjugation; polyurethanes and polyurethane composites from biobased / recycled components. |
| bioconjugate chemistry impact factor: Mass Spectrometry Bulletin , 1996 |
| bioconjugate chemistry impact factor: Encyclopedia of Cell Biology , 2015-08-07 The Encyclopedia of Cell Biology, Four Volume Set offers a broad overview of cell biology, offering reputable, foundational content for researchers and students across the biological and medical sciences. This important work includes 285 articles from domain experts covering every aspect of cell biology, with fully annotated figures, abundant illustrations, videos, and references for further reading. Each entry is built with a layered approach to the content, providing basic information for those new to the area and more detailed material for the more experienced researcher. With authored contributions by experts in the field, the Encyclopedia of Cell Biology provides a fully cross-referenced, one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences. Fully annotated color images and videos for full comprehension of concepts, with layered content for readers from different levels of experience Includes information on cytokinesis, cell biology, cell mechanics, cytoskeleton dynamics, stem cells, prokaryotic cell biology, RNA biology, aging, cell growth, cell Injury, and more In-depth linking to Academic Press/Elsevier content and additional links to outside websites and resources for further reading A one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences |
Click Chemistry: Reaction Rates and Their Suitability for …
May 22, 2024 · including radiochemistry,3 polymer chemistry,4 peptide chem-istry,5 and pharmaceutical chemistry.6 In recent years, click chemistry has found applications in the study …
Enlightening advances in polymer bioconjugate chemistry: …
conjugation reactions and the eld of bioconjugate synthesis.4,10,12–17 While advances in polymer–protein conjugation chemistry continue, it should be noted that there are inherent …
Bioconjugate Techniques - ETH Z
Bioconjugate Chemistry 1. FunctionalTargets 1. ModificationofAminoacids, Peptides, andProteins 3 1.1. Protein Structure andReactivity 4 AminoAcids 4 NucleophihcReactions andthe pi …
Radiation Cleaved Drug-Conjugate Linkers Enable Local …
Apr 6, 2022 · Cite This: Bioconjugate Chem. 2022, 33, 1474−1484 Read Online ACCESS Metrics & More Article Recommendations * sı Supporting Information ABSTRACT: Conjugation of …
Affinity-Based Methods for Site-Specific Conjugation of …
Jun 17, 2021 · Affinity-Based Methods for Site-Specific Conjugation of Antibodies Emma von Witting, Sophia Hober, and Sara Kanje* Cite This: Bioconjugate Chem. 2021, 32, 1515−1524 …
The Impact of Emerging Bioconjugation Chemistries on …
The Impact of Emerging Bioconjugation Chemistries on Radiopharmaceuticals Rachael Fay and Jason P. Holland Department of Chemistry, University of Zurich, Zurich, Switzerland The use of …
Chemoenzymatic Conjugation of Toxic Payloads to the …
Bioconjugate Chem. 2015, 26, 2233−2242 This is an open access article published under an ACS AuthorChoice License, which permits copying and redistribution of the article or any …
Nanoparticle Interactions with the Tumor …
growth factor (VEGF) and human epidermal growth factor receptor 2 (HER2) antibodies,35,36 which allow nanomaterials to function as directed drug carriers. This approach has yielded …
Modular Strategy for the Construction of Radiometalated …
Jun 4, 2011 · 2049 0000288d | Bioconjugate Chem. 0 22, 2048 2059 Bioconjugate Chemistry ARTICLE for antibody modification. Not only would this require addi-tional time to develop and …
PEGylated Lipid Nanoparticle Formulations: Immunological …
Cite This: Bioconjugate Chem. 2023, 34, 941−960 Read Online ACCESS Metrics & More Article Recommendations * sı Supporting Information ABSTRACT: Lipid nanoparticles (LNPs) have …
TREN IMPACT FACTOR, PRODUKTIVITAS, DAN KOLABORASI …
year-impact factor formula, Lotka’s law, and Subramanyam formula. The impact factor is 0,006 in 2010 and 0,007 in 2011. The result shows 88 of 90 citations are self-citations from IJC 2007 …
Facile Chemical Functionalization of Proteins through Intein …
Facile Chemical Functionalization of Proteins through Intein-Linked Yeast Display Carrie J. Marshall,† Nitin Agarwal,† Jeet Kalia,‡ Vanessa A. Grosskopf,† Nicholas A. McGrath,§ …
Targeted Delivery of siRNA to Hepatocytes and Hepatic …
the validated siRNA duplexes targeting firefly luciferase and transforming growth factor beta 1 (TGF- 1) mRNA were conjugated to Gal-PEG and M6P-PEG, and their gene silencing …
High-Affinity Points of Interaction on Antibody Allow …
May 19, 2021 · nanoparticle conjugate, specifically the interfacial chemistry to immobilize the surface protein. The protein should retain its native conformation and confer an appropriate …
Designing Hybrid Antibiotic Peptide Conjugates To Cross …
†Bioengineering Department, ‡Chemistry and Biochemistry Department, and §California NanoSystems Institute, University of California, Los Angeles, 410 Westwood Plaza, Los …
If you require this document in an alternative format, please …
1 Characterization of reactions between water soluble trialkylphosphines and thiol alkylating reagents: Implications for protein conjugation reactions
科学技術動向研究 学術論文誌の編集体制にみる日本の 研究 …
Applied Materials & Interfaces, Advances in Chemistry, Analytical Chemistry, Bioconjugate Chemistry, Biomacromolecules, Inorganic Chemistry, Journal of the American Chemical …
Tyrosine-Selective Functionalization for Bio-Orthogonal Cross …
Tyrosine-Selective Functionalization for Bio-Orthogonal Cross-Linking of Engineered Protein Hydrogels Christopher M. Madl† and Sarah C. Heilshorn*,‡ †Department of Bioengineering …
Click Chemistry and Radiochemistry: An Update - ACS …
Jun 30, 2023 · not been touched by click chemistry, some have inevitably been influenced more than others. Along these lines, radiopharmaceutical chemistry is a standout example, as the …
Moving Protein PEGylation from an Art to a Data Science
Moving Protein PEGylation from an Art to a Data Science Leran Mao, Alan J. Russell, and Sheiliza Carmali* Cite This: Bioconjugate Chem. 2022, 33, 1643−1653 Read Online ACCESS …
Non-Genetic Generation of Antibody Conjugates Based on …
Cite This: Bioconjugate Chem. 2021, 32, 2167−2172 Read Online ACCESS Metrics & More Article Recommendations * sı Supporting Information ABSTRACT: The availability of tools to generate …
Quantification of Primary Amine Groups Available for …
Jul 7, 2011 · Bioconjugate Chemistry ARTICLE amount of subsequently grafted molecules have never been clearly established.10,11 In this work, quantitative values of amino group density were
Tandem-Cleavage Linkers Improve the In Vivo Stability and …
control compounds 3 and 4, respectively, were added to the study (Table 1). Compound 5 is vedotin, the cysteine-reactive vcMMAE construct that has been most commonly used in
AJICAP Second Generation: Improved Chemical Site-Specific …
Jan 30, 2023 · linkers. For example, MC-VC-MMAE, a commonly used ADC drug linker in the market,6 cannot be applied to this high DAR technology because hydrophobicity causes …
Photocontrolled Release of Doxorubicin Conjugated …
Bioconjugate Chemistry Document Version: Peer reviewed version Queen's University Belfast - Research Portal: ... designed to be cleaved selectively in response to an endogenous factor …
pH Impacts the Orientation of Antibody Adsorbed onto Gold …
coupling chemistry, direct adsorption of antibody onto AuNPs is still routinely used.33−38 Interest in protein-AuNP interactions has been renewed with the significant role of protein coronas in …
Precision Modification of Native Antibodies - NSF Public Access
stability, and/or production yield and cost. Accordingly, concurrent with advances in the fields of bioorthogonal chemistry and protein engineering, there is growing interest in site-specifically …
Biofunctionalized Gadolinium-Containing Prussian Blue …
the potential to impact clinical care by reducing or simplifying patient preparation steps required in clinical molecular imaging. In this article, we describe biofunctionalized Prussian blue …
Reversible Chemical Modification of Antibody Effector …
May 7, 2024 · Bioconjugate Chem. XXXX, XXX, XXX ... .31 CD40 is a member of the tumor necrosis factor (TNF) receptor superfamily and is expressed on all B-cell lineages and ...
UC San Francisco Previously Published Works - eScholarship
Bioconjugate Chemistry, 24(1) ISSN 1043-1802 Authors Walsh, Colin L Nguyen, Juliane Tiffany, Matthew R et al. Publication Date 2013-01-16 DOI 10.1021/bc300346h Peer reviewed …
BIOCONJUGATE TECHNIQUES - ETH Z
BIOCONJUGATE TECHNIQUES GregT. Hermanson Pierce Biotechnology, ThermoFisherScientific, Rockford, IL ELSEVIER AMSTERDAM ... ClickChemistry: …
Bioconjugate Therapeutics: Current Progress and Future …
May 1, 2017 · bioconjugate therapeutics. Karuturi et al. constructed a bioconjugate vaccine (pp89-RR-EP67) composed of a host-derived mucosal immunostimulant (EP67), a protective MCMV …
Copper-Catalyzed Azide–Alkyne Click Chemistry for …
3. Dilute the reaction mixture by a factor of 4 with buffer to obtain a solution approx-imately 25 μM in triazole 4. In this dilution step, include protein X, if possible (or a surrogate protein such as …
ACS数据库学术资源，助力科研学习与成果发表
Bioconjugate IMPACT FACTOR Chemistry 2.9 IMPACT FACTOR 3.7 IMPACT FACTOR 4.0 Biotechnology ...
Vitamin B in drug delivery: breaking through the barriers to a …
12 bioconjugate pharmaceutical Susan M Clardy, Damian G Allis, Timothy J Fairchild & Robert P Doyle † † Syracuse University, Syracuse, Department of Chemistry, NY 13244-4100, USA
Job Title: Postdoc in Graphene Bioconjugate Chemistry
graphene-bioconjugate-chemistry-nanomedicine-group and include the following: 1. A cover letter. 2. A full CV including contact details. 3. 2 Reference letters or referee contacts. Equal …
Bioconjugate Chem. 2009, 20, 5–14 5 REVIEWS - Bio-Syn
Bioconjugate Chem. 2009, 20, 5–14 5 10.1021/bc800278e CCC: $40.75 2009 American Chemical Society ... for Synthesis of siRNA Conjugates siRNA conjugate site of conjugation (I) site of …
Prof. Angela Casini Curriculum Vitae - EURASC
2 Board of Chemistry Eur. J. and of J. Inorg.Biochem., and has served in the editorial advisory board of other journals (e.g. ACS Bioconjugate Chemistry, Inorganic Chemistry). She has also …
Chemistry journals impact factors in web of science (ISI) for …
during 2016 to 2017 with an impact factor of 5.836. Chemistry /analytical (84 journals) Aggregate impact factor (Table 3) The study showed the total number of citations obtained by the issues …
University of Birmingham Self-assembly of temperature …
bioconjugate was found to remain functionally active (i.e., fluorescent) after conjugation. Turbidity measurements revealed that the point of attachment of the polymer onto the protein scaffold …
Bioorthogonal Fluorophore Linked DFO Technology Enabling …
establish the A280/A500 ratio of the dye after tetrazine ligation. This correction factor allows quantification of the BODIPY contribution to the A280 of the conjugate, enabling deconvolution …
Impact of Multiple Negative Charges on Blood Clearance and
Impact of Multiple Negative Charges on Blood Clearance and ... Von Willebrand’s factor, and osteoponin) with the arginine-glycine-aspartic (RGD) peptide sequence.5 Over last several …
Antibody Drug Conjugates for Tumor Targeting Novel …
Bioconjugate Chem. 2015, 26, 2176−2185. such that the (usually) hydrophobic drug can cross the ... potency of classical chemotherapeutic drugs by a factor of about 1000.2 As the first, …
In Vivo Pretargeting Based on Cysteine-Selective Antibody …
Modification with IEDDA Bioorthogonal Handles for Click Chemistry Vera F. C. Ferreira, Bruno L. Oliveira,* Alice D’Onofrio, Carlos M. Farinha, Lurdes Gano, António Paulo, Gonc ̧alo J. L. …
Well-Defined Multivalent Ligands for Hepatocytes Targeting …
Nov 8, 2016 · Bioconjugate Chem. 2017, 28, 283−295 two distinct genes. 10,25 In humans, the major subunit H1 and the minor subunit H2 are 46 and 50 kDa in size, respectively,
Curriculum Vitae of Dr. SAMIT GUHA - Jadavpur University
2 F. Awards/Recognition/Honors G. Project Principal Investigator, SERB-DST Early Career Award, Govt. of India (File No. ECR/2017/001405" dated 6th July, 2018), Molecular …
Journal of Pharmaceutical Sciences
“Negative” Impact: The Role of Payload Charge in the ... ing factor for ADC instability.16,17 To address this gap, this study investigated the mechanisms by which subtle alterations in …
Best Wishes for the Coming Year from the Folks at …
Jan 19, 2022 · Best Wishes for the Coming Year from the Folks at Bioconjugate Chemistry Cite This: Bioconjugate Chem. 2022, 33, 1−3 Read Online ACCESS Metrics & More Article …
Design, Synthesis, and Antitumor Evaluation of an Opioid …
Growth Factor Bioconjugate Targeting Pancreatic Ductal Adenocarcinoma Justyna Budka 1 , Dawid Debowski 2 , Shaoshan Mai 1 , Magdalena Narajczyk 3 , Stanislaw Hac 4 , Krzysztof …
Elucidating the Impact of Payload Conjugation on the Cell …
A caveat of the presented protein design relates to the presence of disulfidebonds. Specifically,disulfidebond shuffling could lead to 2 generating 1 and 3, and 4 generating 1 and 5.
