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| biology definition of passive transport: Principles of Biology Lisa Bartee, Walter Shiner, Catherine Creech, 2017 The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research. |
| biology definition of passive transport: Molecular Biology of the Cell , 2002 |
| biology definition of passive transport: Concepts of Biology Samantha Fowler, Rebecca Roush, James Wise, 2023-05-12 Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy. |
| biology definition of passive transport: Exocytosis and Endocytosis Andrei I. Ivanov, 2008 In this book, skilled experts provide the most up-to-date, step-by-step laboratory protocols for examining molecular machinery and biological functions of exocytosis and endocytosis in vitro and in vivo. The book is insightful to both newcomers and seasoned professionals. It offers a unique and highly practical guide to versatile laboratory tools developed to study various aspects of intracellular vesicle trafficking in simple model systems and living organisms. |
| biology definition of passive transport: Biology for AP ® Courses Julianne Zedalis, John Eggebrecht, 2017-10-16 Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences. |
| biology definition of passive transport: Cells: Molecules and Mechanisms Eric Wong, 2009 Yet another cell and molecular biology book? At the very least, you would think that if I was going to write a textbook, I should write one in an area that really needs one instead of a subject that already has multiple excellent and definitive books. So, why write this book, then? First, it's a course that I have enjoyed teaching for many years, so I am very familiar with what a student really needs to take away from this class within the time constraints of a semester. Second, because it is a course that many students take, there is a greater opportunity to make an impact on more students' pocketbooks than if I were to start off writing a book for a highly specialized upper- level course. And finally, it was fun to research and write, and can be revised easily for inclusion as part of our next textbook, High School Biology.--Open Textbook Library. |
| biology definition of passive transport: An Introduction to Biological Membranes William Stillwell, 2013-04-20 An Introduction to Biological Membranes: From Bilayers to Rafts covers many aspects of membrane structure/function that bridges membrane biophysics and cell biology. Offering cohesive, foundational information, this publication is valuable for advanced undergraduate students, graduate students and membranologists who seek a broad overview of membrane science. - Brings together different facets of membrane research in a universally understandable manner - Emphasis on the historical development of the field - Topics include membrane sugars, membrane models, membrane isolation methods, and membrane transport |
| biology definition of passive transport: Anatomy and Physiology J. Gordon Betts, Peter DeSaix, Jody E. Johnson, Oksana Korol, Dean H. Kruse, Brandon Poe, James A. Wise, Mark Womble, Kelly A. Young, 2013-04-25 |
| biology definition of passive transport: Membrane Physiology Thomas E. Andreoli, Darrell D. Fanestil, Joseph F. Hoffman, Stanley G. Schultz, 2012-12-06 Membrane Physiology (Second Edition) is a soft-cover book containing portions of Physiology of Membrane Disorders (Second Edition). The parent volume contains six major sections. This text encompasses the first three sections: The Nature of Biological Membranes, Methods for Studying Membranes, and General Problems in Membrane Biology. We hope that this smaller volume will be helpful to individuals interested in general physiology and the methods for studying general physiology. THOMAS E. ANDREOLI JOSEPH F. HOFFMAN DARRELL D. FANESTIL STANLEY G. SCHULTZ vii Preface to the Second Edition The second edition of Physiology of Membrane Disorders represents an extensive revision and a considerable expansion of the first edition. Yet the purpose of the second edition is identical to that of its predecessor, namely, to provide a rational analysis of membrane transport processes in individual membranes, cells, tissues, and organs, which in tum serves as a frame of reference for rationalizing disorders in which derangements of membrane transport processes playa cardinal role in the clinical expression of disease. As in the first edition, this book is divided into a number of individual, but closely related, sections. Part V represents a new section where the problem of transport across epithelia is treated in some detail. Finally, Part VI, which analyzes clinical derangements, has been enlarged appreciably. |
| biology definition of passive transport: The Molecular Biology of Plant Cells H. Smith, Harry Smith, 1977-01-01 Plant cell structure and function; Gene expression and its regulation in plant cells; The manipulation of plant cells. |
| biology definition of passive transport: Transport in Plants II U. Lüttge, M.G. Pitman, 1976-05-01 As plant physiology increased steadily in the latter half of the 19th century, problems of absorption and transport of water and of mineral nutrients and problems of the passage of metabolites from one cell to another were investigated, especially in Germany. JUSTUS VON LIEBIG, who was born in Darmstadt in 1803, founded agricultural chemistry and developed the techniques of mineral nutrition in agricul ture during the 70 years of his life. The discovery of plasmolysis by NAGEL! (1851), the investigation of permeability problems of artificial membranes by TRAUBE (1867) and the classical work on osmosis by PFEFFER (1877) laid the foundations for our understanding of soluble substances and osmosis in cell growth and cell mechanisms. Since living membranes were responsible for controlling both water movement and the substances in solution, permeability became a major topic for investigation and speculation. The problems then discussed under that heading included passive permeation by diffusion, Donnan equilibrium adjustments, active transport processes and antagonism between ions. In that era, when organelle isolation by differential centrifugation was unknown and the electron microscope had not been invented, the number of cell membranes, their thickness and their composition, were matters for conjecture. The nature of cell surface membranes was deduced with remarkable accuracy from the reactions of cells to substances in solution. In 1895, OVERTON, in U. S. A. , published the hypothesis that membranes were probably lipid in nature because of the greater penetration by substances with higher fat solubility. |
| biology definition of passive transport: Inanimate Life George M. Briggs, 2021-07-16 |
| biology definition of passive transport: Cell Biology by the Numbers Ron Milo, Rob Phillips, 2015-12-07 A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid |
| biology definition of passive transport: Cellular Physiology and Neurophysiology E-Book Mordecai P. Blaustein, Joseph P. Y. Kao, Donald R. Matteson, 2011-12-14 Gain a quick and easy understanding of this complex subject with the 2nd edition of Cellular Physiology and Neurophysiology by doctors Mordecai P. Blaustein, Joseph PY Kao, and Donald R. Matteson. The expanded and thoroughly updated content in this Mosby Physiology Monograph Series title bridges the gap between basic biochemistry, molecular and cell biology, neuroscience, and organ and systems physiology, providing the rich, clinically oriented coverage you need to master the latest concepts in neuroscience. See how cells function in health and disease with extensive discussion of cell membranes, action potentials, membrane proteins/transporters, osmosis, and more. Intuitive and user-friendly, this title is a highly effective way to learn cellular physiology and neurophysiology. Focus on the clinical implications of the material with frequent examples from systems physiology, pharmacology, and pathophysiology. Gain a solid grasp of transport processes—which are integral to all physiological processes, yet are neglected in many other cell biology texts. Understand therapeutic interventions and get an updated grasp of the field with information on recently discovered molecular mechanisms. Conveniently explore mathematical derivations with special boxes throughout the text. Test your knowledge of the material with an appendix of multiple-choice review questions, complete with correct answers Understand the latest concepts in neurophysiology with a completely new section on Synaptic Physiology. Learn all of the newest cellular physiology knowledge with sweeping updates throughout. Reference key abbreviations, symbols, and numerical constants at a glance with new appendices. |
| biology definition of passive transport: Cell Organelles Reinhold G. Herrmann, 2012-12-06 The compartmentation of genetic information is a fundamental feature of the eukaryotic cell. The metabolic capacity of a eukaryotic (plant) cell and the steps leading to it are overwhelmingly an endeavour of a joint genetic cooperation between nucleus/cytosol, plastids, and mitochondria. Alter ation of the genetic material in anyone of these compartments or exchange of organelles between species can seriously affect harmoniously balanced growth of an organism. Although the biological significance of this genetic design has been vividly evident since the discovery of non-Mendelian inheritance by Baur and Correns at the beginning of this century, and became indisputable in principle after Renner's work on interspecific nuclear/plastid hybrids (summarized in his classical article in 1934), studies on the genetics of organelles have long suffered from the lack of respectabil ity. Non-Mendelian inheritance was considered a research sideline~ifnot a freak~by most geneticists, which becomes evident when one consults common textbooks. For instance, these have usually impeccable accounts of photosynthetic and respiratory energy conversion in chloroplasts and mitochondria, of metabolism and global circulation of the biological key elements C, N, and S, as well as of the organization, maintenance, and function of nuclear genetic information. In contrast, the heredity and molecular biology of organelles are generally treated as an adjunct, and neither goes as far as to describe the impact of the integrated genetic system. |
| biology definition of passive transport: The Cell Geoffrey M. Cooper, 2000 The field of cell biology is so vast and changing so rapidly that teaching it can be a daunting prospect. The first edition of The Cell: A Molecular Approach, published in 1997, offered the perfect solution for teachers and their students-current, comprehensive science combined with the readability and cohesiveness of a single- authored text. Designed for one-semester introductory cell biology courses, this book enabled students to master the material in the entire book, not simply to sample a small fraction from a much larger text. The new second edition of The Cell retains the organization, themes, and special features of the original, but has been completely updated in major areas of scientific progress, including genome analysis; chromatin and transcription; nuclear transport; protein sorting and trafficking; signal transduction; the cell cycle; and programmed cell death. With a clear focus on cell biology as an integrative theme, topics such as developmental biology, plant biology, the immune system, the nervous system, and muscle physiology are covered in their broader biological context. Each chapter includes a brief chapter outline, bold-faced key terms, and chapter-end questions with answers in the back of the book. |
| biology definition of passive transport: Encyclopedia of Bone Biology , 2020-06-26 Encyclopedia of Bone Biology, Three Volume Set covers hot topics from within the rapidly expanding field of bone biology and skeletal research, enabling a complete understanding of both bone physiology and its relation to other organs and pathophysiology. This encyclopedia will serve as a vital resource for those involved in bone research, research in other fields that cross link with bone, such as metabolism and immunology, and physicians who treat bone diseases. Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from advanced undergraduate students to research professionals. Chapters also explore the latest advances and hot topics that have emerged in recent years, including the Hematopoietic Niche and Nuclear Receptors. In the electronic edition, each chapter will include hyperlinked references and further readings as well as cross-references to related articles. Incorporates perspectives from experts working within the domains of biomedicine, including physiology, pathobiology, pharmacology, immunology, endocrinology, orthopedics and metabolism Provides an authoritative introduction for non-specialists and readers from undergraduate level upwards, as well as up-to-date foundational content for those familiar with the field Includes multimedia features, cross-references and color images/videos |
| biology definition of passive transport: Oxford IB Diploma Programme: Biology Course Companion Andrew Allott, David Mindorff, 2014-03-06 The only DP Biology resource developed with the IB to accurately match the new 2014 syllabus for both SL and HL, this completely revised edition gives you unparallelled support for the new concept-based approach to learning, the Nature of science.. Understanding, applications and skills are integrated in every topic, alongside TOK links and real-world connections to drive inquiry and independent learning. Assessment support directly from the IB includes practice questions and worked examples in each topic, along with focused support for the Internal Assessment. Truly aligned with the IB philosophy, this Course Book gives unrivalled insight and support at every stage. ·Accurately cover the new syllabus - the most comprehensive match, with support directly from the IB on the core, AHL and all the options ·Fully integrate the new concept-based approach, holistically addressing understanding, applications, skills and the Nature of science ·Tangibly build assessment potential with assessment support str |
| biology definition of passive transport: Concepts in Cell Biology Vaidurya Pratap Sahi, F. Baluška, 2018 This book discusses central concepts and theories in cell biology from the ancient past to the 21st century, based on the premise that understanding the works of scientists like Hooke, Hofmeister, Caspary, Strasburger, Sachs, Schleiden, Schwann, Mendel, Nemec, McClintock, etc. in the context of the latest advances in plant cell biology will help provide valuable new insights. Plants have been an object of study since the roots of the Greek, Chinese and Indian cultures. Since the term cell was first coined by Robert Hooke, 350 years ago in Micrographia, the study of plant cell biology has moved ahead at a tremendous pace. The field of cell biology owes its genesis to physics, which through microscopy has been a vital source for piquing scientists' interest in the biology of the cell. Today, with the technical advances we have made in the field of optics, it is even possible to observe life on a nanoscale. From Hooke's observations of cells and his inadvertent discovery of the cell wall, we have since moved forward to engineering plants with modified cell walls. Studies on the chloroplast have also gone from Julius von Sachs' experiments with chloroplast, to using chloroplast engineering to deliver higher crop yields. Similarly, advances in fluorescent microscopy have made it far easier to observe organelles like chloroplast (once studied by Sachs) or actin (observed by Bohumil Nemec). If physics in the form of cell biology has been responsible for one half of this historical development, biochemistry has surely been the other. |
| biology definition of passive transport: Anatomy & Physiology Lindsay Biga, Devon Quick, Sierra Dawson, Amy Harwell, Robin Hopkins, Joel Kaufmann, Mike LeMaster, Philip Matern, Katie Morrison-Graham, Jon Runyeon, 2019-09-26 A version of the OpenStax text |
| biology definition of passive transport: Principles and Models of Biological Transport Morton H. Friedman, 2012-12-06 This text is designed for a first course in biological mass transport, and the material in it is presented at a level that is appropriate to advanced undergraduates or early graduate level students. Its orientation is somewhat more physical and mathematical than a biology or standard physiology text, reflecting its origins in a transport course that I teach to undergraduate (and occasional graduate) biomedical engineering students in the Whiting School of Engineering at Johns Hopkins. The audience for my cours- and presumably for this text - also includes chemical engineering undergraduates concentrating in biotechnology, and graduate students in biophysics. The organization of this book differs from most texts that at tempt to present an engineering approach to biological transport. What distinguishes biological transport from other mass transfer processes is the fact that biological transport is biological. Thus, we do not start with the engineering principles of mass transport (which are well presented elsewhere) and then seek biological ap plications of these principles; rather, we begin with the biological processes themselves, and then develop the tools that are needed to describe them. As a result, more physiology is presented in this text than is often found in books dealing with engineering applica tions in the life sciences. |
| biology definition of passive transport: Basic Physiology for Anaesthetists David Chambers, Christopher Huang, Gareth Matthews, 2019-07-25 Easily understood, up-to-date and clinically relevant, this book provides junior anaesthetists with an essential physiology resource. |
| biology definition of passive transport: Transport And Diffusion Across Cell Membranes Wilfred Stein, 2012-12-02 Transport and Diffusion across Cell Membranes is a comprehensive treatment of the transport and diffusion of molecules and ions across cell membranes. This book shows that the same kinetic equations (with appropriate modification) can describe all the specialized membrane transport systems: the pores, the carriers, and the two classes of pumps. The kinetic formalism is developed step by step and the features that make a system effective in carrying out its biological role are highlighted. This book is organized into six chapters and begins with an introduction to the structure and dynamics of cell membranes, followed by a discussion on how the membrane acts as a barrier to the transmembrane diffusion of molecules and ions. The following chapters focus on the role of the membrane's protein components in facilitating transmembrane diffusion of specific molecules and ions, measurements of diffusion through pores and the kinetics of diffusion, and the structure of such pores and their biological regulation. This book methodically introduces the reader to the carriers of cell membranes, the kinetics of facilitated diffusion, and cotransport systems. The primary active transport systems are considered, emphasizing the pumping of an ion (sodium, potassium, calcium, or proton) against its electrochemical gradient during the coupled progress of a chemical reaction while a conformational change of the pump enzyme takes place. This book is of interest to advanced undergraduate students, as well as to graduate students and researchers in biochemistry, physiology, pharmacology, and biophysics. |
| biology definition of passive transport: Sleep and Brain Activity Marcos G. Frank, 2012-07-25 Sleep and the Brain presents some of the more dramatic developments in our understanding of brain activity in sleep. The book discusses what parts of the brain are active in sleep and how, and presents research on the function of sleep in memory, learning, and further brain development. |
| biology definition of passive transport: The Plant Plasma Membrane Angus S. Murphy, Wendy Peer, Burkhard Schulz, 2010-11-11 In plant cells, the plasma membrane is a highly elaborated structure that functions as the point of exchange with adjoining cells, cell walls and the external environment. Transactions at the plasma membrane include uptake of water and essential mineral nutrients, gas exchange, movement of metabolites, transport and perception of signaling molecules, and initial responses to external biota. Selective transporters control the rates and direction of small molecule movement across the membrane barrier and manipulate the turgor that maintains plant form and drives plant cell expansion. The plasma membrane provides an environment in which molecular and macromolecular interactions are enhanced by the clustering of proteins in oligimeric complexes for more efficient retention of biosynthetic intermediates, and by the anchoring of protein complexes to promote regulatory interactions. The coupling of signal perception at the membrane surface with intracellular second messengers also involves transduction across the plasma membrane. Finally, the generation and ordering of the external cell walls involves processes mediated at the plant cell surface by the plasma membrane. This volume is divided into three sections. The first section describes the basic mechanisms that regulate all plasma membrane functions. The second describes plasma membrane transport activity. The final section of the book describes signaling interactions at the plasma membrane. These topics are given a unique treatment in this volume, as the discussions are restricted to the plasma membrane itself as much as possible. A more complete knowledge of the plasma membrane’s structure and function is essential to current efforts to increase the sustainability of agricultural production of food, fiber, and fuel crops. |
| biology definition of passive transport: The Biophysics of Cell Membranes Richard M. Epand, Jean-Marie Ruysschaert, 2017-09-25 This volume focuses on the modulation of biological membranes by specific biophysical properties. The readers are introduced to emerging biophysical approaches that mimick specific states (like membrane lipid asymmetry, membrane curvature, lipid flip-flop, lipid phase separation) that are relevant to the functioning of biological membranes. The first chapter describes innovative methods to mimic the prevailing asymmetry in biological membranes by forming asymmetrical membranes made of monolayers with different compositions. One of the chapters illustrates how physical parameters, like curvature and elasticity, can affect and modulate the interactions between lipids and proteins. This volume also describes the sensitivity of certain ion channels to mechanical forces and it presents an analysis of how cell shape is determined by both the cytoskeleton and the lipid domains in the membrane. The last chapter provides evidence that liposomes can be used as a minimal cellular model to reconstitute processes related to the origin of life. Each topic covered in this volume is presented by leading experts in the field who are able to present clear, authoritative and up-to-date reviews. The novelty of the methods proposed and their potential for a deeper molecular description of membrane functioning are particularly relevant experts in the areas of biochemistry, biophysics and cell biology, while also presenting clear and thorough introductions, making the material suitable for students in these fields as well. |
| biology definition of passive transport: Color Atlas of Biochemistry Jan Koolman, Klaus Heinrich Roehm, 2011-01-01 Totally revised and expanded, the Color Atlas of Biochemistry presents the fundamentals of human and mammalian biochemistry on 215 stunning color plates.Alongside a short introduction to chemistry and the classical topics of biochemistry, the 2nd edition covers new approaches and aspects in biochemistry, such as links between chemical structure and biological function or pathways for information transfer, as well as recent developments and discoveries, such as the structures of many new important molecules. Key features of this title include:- The unique combination of highly effective color graphics and comprehensive figure legends;- Unified color-coding of atoms, coenzymes, chemical classes, and cell organelles that allows quick recognition of all involved systems;- Computer graphics provide simulated 3D representation of many important molecules.This Flexibook is ideal for students of medicine and biochemistry and a valuable source of reference for practitioners. |
| biology definition of passive transport: Phloem Transport S. Aronoff, 2012-12-06 Ten years ago, at the International Botanical Congress in Edinburgh, a group of us from various countries discussed the difficulty of pursuing academic problems in depth at such meetings. In particular, we were discouraged at the poverty of time for phloem transport. From long association, we were conscious of the extraordinary breadth of the problem, from developmental through anatomical, to biophysical and physiological. Only by a reasonable understanding of all these components could one hope to come to some kind of understanding. We decided to establish common plant material so that data would have a common source. Similarly, we resolved to exchange information by circulating pre-publication manuscripts. For awhile, after the meeting was a pleasant memory, the plan seemed to be working; but, as is so often the case, human infirmities and foibles played early and, subsequently, predominant roles. Some became administrators (a punishment for good behaviour); others concentrated on alternative rings in their academic circuses. The next Congress (in Seattle) proved similar to its predecessor in its neglect and, consequently, succor was sought elsewhere. A little known, but remarkably understanding group becoming visible was the Science Committee and the Division of Scientific Affairs of N. A. T. O. Its sponsorship of Advanced Study Institutes including phytochemistry and phytophysics, was unusual both in the generosity of its funding and in the requirements for academic quality. |
| biology definition of passive transport: Pesticide Biotransformation and Disposition Ernest Hodgson, 2012-01-01 Biotransformation of Pesticides is an updated, one-stop resource for academic, industry and regulatory scientists involved in research and regulatory activities related to pesticide biotransformation and human health. This book provides an in depth look at how pesticides are biotransformed, which is essential to understanding exposure, dose, toxicity and health risks. This essential reference contains the biotransformation of pesticides from uptake to excretion, including toxicokinetics and emphasizes metabolism in non-target species, including experimental animals and humans. - Includes four new chapters and expanded material on pesticide biotransformation and disposition, an active area of pesticide toxicology that is becoming increasingly important for human health risk assessment - Offers a practical and portable guide covering the most up-to-date research results on metabolic transformations of pesticides - Provides scientists and regulatory researchers with the information they need to conduct accurate risk assessments and make informed decisions on which exposures to study further in human populations |
| biology definition of passive transport: Plant Cell Walls Nicholas C. Carpita, Malcolm Campbell, Mary Tierney, 2012-12-06 This work is a comprehensive collection of articles that cover aspects of cell wall research in the genomic era. Some 2500 genes are involved in some way in wall biogenesis and turnover, from generation of substrates, to polysaccharide and lignin synthesis, assembly, and rearrangement in the wall. Although a great number of genes and gene families remain to be characterized, this issue provides a census of the genes that have been discovered so far. The articles comprising this issue not only illustrate the enormous progress made in identifying the wealth of wall-related genes but they also show the future directions and how far we have to go. As cell walls are an enormously important source of raw material, we anticipate that cell-wall-related genes are of significant economic importance. Examples include the modification of pectin-cross-linking or cell-cell adhesion to increase shelf life of fruits and vegetables, the enhancement of dietary fiber contents of cereals, the improvement of yield and quality of fibers, and the relative allocation of carbon to wall biomass for use as biofuels. The book is intended for academic and professional scientists working in the area of plant biology as well as material chemists and engineers, and food scientists who define new ways to use cell walls. |
| biology definition of passive transport: PH and Brain Function Kai Kaila, Bruce R. Ransom, 1998-09-15 PH and Brain Function offers thorough coverage of this increasingly important area of research, beginning with the fundamental concepts, which include methodological and theoretical issues such as the measurement of pH and the concept of pH in neurobiology. It explores aspects of regulation and modulation of intracellular pH in brain cells, surveys the changes in pH that occur with neural activity and how these changes affect neural activity, and discusses the role of pH in the pathophysiology of neurological diseases. pH and Brain Function is an important resource for researchers in all areas of neuroscience as well as cell biology and physiology. --Book Jacket. |
| biology definition of passive transport: Biological Markers in Psychiatry and Neurology Earl Usdin, Israel Hanin, 2013-10-22 Biological Markers in Psychiatry and Neurology is a collection of papers that details the advancement in the understanding of the biological markers that stems from psychiatric and neurological pathologies. The text first covers topics about various biological markers, such as neurochemical, enzymatic, membrane, receptors, endocrine, and physiological. Next, the selection examines the relationship between alcohol abuse and biological papers. The next part covers the genetic aspects of biological markers. The text also deals with use of tomography and modeling theory. The book will be of great use to students, researchers, and practitioners of neurology and psychiatry. Psychologists will also benefit from the text. |
| biology definition of passive transport: Drug-like Properties: Concepts, Structure Design and Methods Li Di, Edward H Kerns, 2010-07-26 Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process. The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance. The authors also review various methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties. - Serves as an essential working handbook aimed at scientists and students in medicinal chemistry - Provides practical, step-by-step guidance on property fundamentals, effects, structure-property relationships, and structure modification strategies - Discusses improvements in pharmacokinetics from a practical chemist's standpoint |
| biology definition of passive transport: Oral Drug Absorption Jennifer B. Dressman, Christos Reppas, 2016-04-19 Oral Drug Absorption, Second Edition thoroughly examines the special equipment and methods used to test whether drugs are released adequately when administered orally. The contributors discuss methods for accurately establishing and validating in vitro/in vivo correlations for both MR and IR formulations, as well as alternative approaches for MR an |
| biology definition of passive transport: The Membranes of Cells Philip Yeagle, 1993 In this new edition of The Membranes of Cells, all of the chapters have been updated, some have been completely rewritten, and a new chapter on receptors has been added. The book has been designed to provide both the student and researcher with a synthesis of information from a number of scientific disciplines to create a comprehensive view of the structure and function of the membranes of cells. The topics are treated in sufficient depth to provide an entry point to the more detailed literature needed by the researcher. Key Features * Introduces biologists to membrane structure and physical chemistry * Introduces biophysicists to biological membrane function * Provides a comprehensive view of cell membranes to students, either as a necessary background for other specialized disciplines or as an entry into the field of biological membrane research * Clarifies ambiguities in the field |
| biology definition of passive transport: Fossil Crinoids Hans Hess, William I. Ausich, Carlton E. Brett, Michael J. Simms, 2002 Crinoids have graced the oceans for more than 500 million years. Among the most attractive fossils, crinoids had a key role in the ecology of marine communities through much of the fossil record, and their remains are prominent rock forming constituents of many limestones. This is the first comprehensive volume to bring together their form and function, classification, evolutionary history, occurrence, preservation and ecology. The main part of the book is devoted to assemblages of intact fossil crinoids, which are described in their geological setting in twenty-three chapters ranging from the Ordovician to the Tertiary. The final chapter deals with living sea lilies and feather stars. The volume is exquisitely illustrated with abundant photographs and line drawings of crinoids from sites around the world. This authoritative account recreates a fascinating picture of fossil crinoids for paleontologists, geologists, evolutionary and marine biologists, ecologists and amateur fossil collectors. |
| biology definition of passive transport: Membrane Contactors: Fundamentals, Applications and Potentialities Enrico Drioli, A. Criscuoli, E. Curcio, 2011-08-30 Membrane Contactors: Fundamentals, Applications and Potentialities, Volume 11 covers new operations that could be efficiently used to improve the performance of a variety of industrial production cycles in applications ranging from biotechnology to agrofood. This book focuses on the basic principles of work: required membrane materials and properties; major operating parameters; the importance of module configuration and design and; the performance of membrane contactors in specific processes. The authors' dynamic approach to this subject makes Membrane Contactors: Fundamentals, Applications and Potentialities, Volume 11 the most comprehensive book currently available on all aspects related to the 'membrane contactor world.* Describes new unit operations in process engineering* Covers a wide variety of industrial applications, from biotechnology to agrofood* Applicable to process intensification and sustainable growth strategies |
| biology definition of passive transport: Type 2 Diabetes and Dementia Velandai Srikanth, Zoe Arvanitakis, 2018-02-09 Type 2 Diabetes and Dementia details the relationship between diabetes, dementia and the future of medicine and therapeutics. Chapters range from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment and prevention strategies, and the application of therapeutics. The book reflects the translational aspects of the current science in the field, with an emphasis on the display of neuroimaging and neuropathology. It contains contributions from world experts, and is ideal for clinicians and researchers in the fields of neurology, neuroscience, geriatric medicine and endocrinology. - Presents a comprehensive overview that details the relationship between diabetes, dementia and the future of medicine and therapeutics - Written for researchers and clinicians in neurology, neuroscience, geriatric medicine and endocrinology - Includes topics ranging from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment, prevention strategies and therapeutic applications |
| biology definition of passive transport: Human Biochemistry Gerald Litwack, 2021-11-28 **Selected for Doody's Core Titles® 2024 in Biochemistry** Human Biochemistry, Second Edition provides a comprehensive, pragmatic introduction to biochemistry as it relates to human development and disease. Here, Gerald Litwack, award-wining researcher and longtime teacher, discusses the biochemical aspects of organ systems and tissue, cells, proteins, enzymes, insulins and sugars, lipids, nucleic acids, amino acids, polypeptides, steroids, and vitamins and nutrition, among other topics. Fully updated to address recent advances, the new edition features fresh discussions on hypothalamic releasing hormones, DNA editing with CRISPR, new functions of cellular prions, plant-based diet and nutrition, and much more. Grounded in problem-driven learning, this new edition features clinical case studies, applications, chapter summaries, and review-based questions that translate basic biochemistry into clinical practice, thus empowering active clinicians, students and researchers. - Presents an update on a past edition winner of the 2018 Most Promising New Textbook (College) Award (Texty) from the Textbook and Academic Authors Association and the PROSE Award of the Association of American Publishers - Provides a fully updated resource on current research in human and medical biochemistry - Includes clinical case studies, applications, chapter summaries and review-based questions - Adopts a practice-based approach, reflecting the needs of both researchers and clinically oriented readers |
| biology definition of passive transport: Membrane Biochemistry E. Carafoli, G. Semenza, 2012-12-06 This manual collects in the form of laboratory protocols a series of experiments in the field of Membrane Transport and Membrane Bioenergetics. It represents the experience accumulated during four advanced courses held at the Depart ment of Biochemistry of the Swiss Federal Institute of Technology on behalf of Federation of European Biochemical Societies (FEBS) in the years 1975 through 1978. The idea of collecting the experiments into a laboratory manual developed as a response to a demand from the students who took part in the courses. Further motivation came with the fmding that, in planning the laboratory sessions, the teaching staff had no organized, modern source of information in the literature. The experiments presented cover most areas of importance in the subject mat ter. Their presentation has been continuously modified in the course of the four years during which the manual took shape, to accommodate to experience and various suggestions. In their present form, all of the experiments described have been repeatedly practiced to optimize their execution. Efforts have been made to combine in the manual classical experiments, and techniques which require relatively unsophisticated instrumentation and can therefore be carried out in most laboratories, with more modern experiments and relatively newer technol ogies. In its present form, the manual should therefore provide a usefui tool in the hands of researchers and laboratory teachers at different levels of sophisti cation and instrumentation. |
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Jan 28, 2007 · In my introductory biology class, we are learning about how water creates aqueous solutions. I am not sure about the definition of a solution, however. Does a solution mean that …
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Jul 19, 2011 · I can't quite grasp the "ends" of DNA. When we say "3' end", does it mean that we can only add the nucleotides to the 5's, and not the 3's?
WHAT A BIOLOGY? - Biology Forum
Dec 3, 2006 · Biology is the study of living things… In this we study about the structure , function , interactions, of living organisms…It is a vast field divided into many branches. December 3, …
Evolution - Biology Forum
Dec 20, 2007 · Evolution does'nt makes sense to me. According to Darwin, humans have evolved from apes. I want to know why some apes evolved into humans, why not all evolved?
what is depolymerisation - Biology Forum
Jul 23, 2006 · I think depolymerisation is the removal of the monomers, in this case the removal of the monomers of microtubules.
Topics Archive - Biology Forum
360 Wiki Writers. General Discussion. 2; 2
Imperfect Design - Biology Forum
Aug 28, 2007 · Imperfect Design Darwin’s theory of Evolution explains how living things adapt to changing environments over time so as to survive and procreate the species.
Meniscus? - Biology Forum
Apr 21, 2006 · My biology teacher gave us instructions on how to set up a potometer. According to him the way to measure the rate of transpiration is to measure the distance moved by the …
What is the String Theory? - Biology Forum
Feb 15, 2006 · The string theory is a notion of cuantum physics that tries to explain how is it that our space and time can expand and contract influenced by the energy of everything…
How do I cram for the exam??? - Biology Forum
Oct 27, 2009 · I have been studying Biology by correspondence through Unilearn for the last couple of months. I have completed my required 10 modules so getting ready to …
Definition of a solution - Biology Forum
Jan 28, 2007 · In my introductory biology class, we are learning about how water creates aqueous solutions. I am not sure about the definition of a solution, …
DNA 3' end & 5' end - Biology Forum
Jul 19, 2011 · I can't quite grasp the "ends" of DNA. When we say "3' end", does it mean that we can only add the nucleotides to the 5's, …
WHAT A BIOLOGY? - Biology Forum
Dec 3, 2006 · Biology is the study of living things… In this we study about the structure , function , interactions, of living organisms…It is a vast field divided into many branches. …
Evolution - Biology Forum
Dec 20, 2007 · Evolution does'nt makes sense to me. According to Darwin, humans have evolved from apes. I want to know why some apes evolved into humans, why not all …
