biologic therapy for eczema: Dermatology Made Easy Amanda Oakley, 2017-05-06 A concise overview of the common dermatological conditions most likely to present in general medicine From reviews: ... a perfect solution to the constant struggle that dermatology diagnosis presents to primary care physicians and other providers... This well-formatted book covers a vast array of topics ranging from common to rare skin disorders. The pictures are immensely helpful in the understanding of various skin rashes.... Fam Med 2019;51(5):451–452. “... easy to read and informative. One cannot emphasise enough the quality and comprehensive nature of the photographic content.... As someone who was interested in dermatology even as a medical student my only regret is that this book was not around when I was a student as it would have very adequately guided me into my beloved subspecialty.” Ulster Med J 2017;86(3):1–1. “The introduction outlines dermatological conditions by symptom, morphology and body site, providing an excellent index prior to delving into greater detail in the following chapters. The logical approach and level of detail make this text perfect for medical students, interns/residents, primary care physicians and other specialists who wish to quickly identify differential diagnoses or refresh their knowledge of dermatological conditions.” A Lecturer in Dermatology Dermatology Made Easy is based on the hugely popular DermNet New Zealand website and is designed to help GPs, medical students and dermatologists diagnose skin conditions with confidence. The book starts by providing a series of comprehensive tables, complete with over 500 thumbnail photos, to aid diagnosis according to symptoms, morphology, or body site. Once you have narrowed down the diagnosis, cross-references then guide you to more detailed descriptions, and another 700 photographs, covering: common infections inflammatory rashes non-inflammatory conditions skin lesions Every section provides consistent information on the disorder: who gets it and what causes it? what are the clinical features and does it cause any complications? how do you diagnose it? how do you treat it and how long does it take to resolve? The book concludes with a comprehensive section on further investigations and treatment options. Dermatology Made Easy combines the essential focus of the Made Easy book series with the authority and knowledge base of DermNet New Zealand’s unparalleled resources. Printed in full colour throughout. |
biologic therapy for eczema: Safe and Effective Medicines for Children Institute of Medicine, Board on Health Sciences Policy, Committee on Pediatric Studies Conducted Under the Best Pharmaceuticals for Children Act (BPCA) and the Pediatric Research Equity Act (PREA), 2012-10-13 The Best Pharmaceuticals for Children Act (BPCA) and the Pediatric Research Equity Act (PREA) were designed to encourage more pediatric studies of drugs used for children. The FDA asked the IOM to review aspects of pediatric studies and changes in product labeling that resulted from BPCA and PREA and their predecessor policies, as well as assess the incentives for pediatric studies of biologics and the extent to which biologics have been studied in children. The IOM committee concludes that these policies have helped provide clinicians who care for children with better information about the efficacy, safety, and appropriate prescribing of drugs. The IOM suggests that more can be done to increase knowledge about drugs used by children and thereby improve the clinical care, health, and well-being of the nation's children. |
biologic therapy for eczema: Biologic and Systemic Agents in Dermatology Paul S. Yamauchi, 2018-01-02 Written by leading experts in the field and designed for dermatologists and residents, this book includes evidence-based medicine that underscores the clinical data, as well as practical tips on how to use both biologic and systemic agents in the field of dermatology. In the past decade, there have been several groundbreaking advances in medical dermatology. Novel biologic and systemic agents have been developed to treat inflammatory disorders, including psoriasis and atopic dermatitis, as well as skin malignancies such as melanoma. Biologic and Systemic Agents in Dermatology encompasses these developments by describing the mechanism of action of these various agents and the clinical efficacy and safety to treating these respective disorders. The utilization of biologic and systemic agents in other dermatologic conditions, pharmacoeconomics, pharmacovigilance, and clinical trials outcomes are discussed as well as topics including tumor necrosis, conventional systemic agents for psoriatic disease, and oral agents for atopic dermatitis. |
biologic therapy for eczema: Respiratory Disease in Pregnancy Stephen E. Lapinsky, Lauren A. Plante, 2020-04-09 Covers a broad spectrum of respiratory diseases during pregnancy, in order to improve successful management of both mother and fetus. |
biologic therapy for eczema: Handbook of Systemic Drug Treatment in Dermatology Sarah H. Wakelin, Howard I. Maibach, Clive B. Archer, 2015-05-21 The Handbook of Systemic Drug Treatment in Dermatology helps prescribers and patients make rational decisions about drug treatment while considering known risks and potential unwanted effects. Written for dermatologists, family practitioners, pharmacists, and specialist nurses, this completely revised and updated second edition of a bestseller prov |
biologic therapy for eczema: Personalizing Asthma Management for the Clinician Stanley J. Szefler, Fernando Holguin, Michael E Wechsler, 2017-09-22 Personalized medicine is a rapidly emerging area in health care, and asthma management lends itself particularly well to this new development. This practical resource by Dr. Stanley J. Szefler helps you navigate the many asthma medication options available to your patients, as well as providing insights into those which may be introduced within the next several years. - Features a wealth of information on available asthma medications, including new immunomodulators, new responses to treatment, and new treatment strategies at all levels of asthma care. - Prepares you to meet your patients' needs regarding asthma exacerbation prevention and asthma prevention. - Consolidates today's available information and guidance in this timely area into one convenient resource. |
biologic therapy for eczema: Andrews' Diseases of the Skin William D. James, Dirk M. Elston, James R. Treat, Misha A. Rosenbach, 2019-01-18 Now in a fully revised thirteenth edition, Andrews' Diseases of the Skin remains your single-volume, must-have resource for core information in dermatology. From residency through clinical practice, this award-winning title ensures that you stay up to date with new tools and strategies for diagnosis and treatment, new entities and newly recognized diseases, and current uses for tried-and-true and newer medications. It's the reference you'll turn to again and again when faced with a clinical conundrum or therapeutically challenging skin disease. - Utilizes a concise, clinically focused, user-friendly format that clearly covers the full range of common and rare skin diseases. - Provides outstanding visual support with 1,340 illustrations – more than 500 new to this edition. - Presents comprehensively updated information throughout, including new and unusual clinical presentations of syphilis, new diagnostic classifications and therapies for vascular anomalies, and an updated pediatric and genodermatosis review. - Covers new and evolving treatments for inflammatory, neoplastic, and blistering skin diseases among others. New biologics and phosphodiesterase inhibitors for psoriasis and atopic dermatitis, JAK inhibitors for alopecia areata and vitiligo, immune checkpoint inhibitors for melanoma and rituximab for pemphigus are all covered. - Features a revised and revamped cutaneous adverse drug reaction section, including novel eruptions from new and emerging chemotherapeutic agents and small molecule/targeted inhibitors. - Discusses new and emerging viruses including Zika and human polyomaviruses. |
biologic therapy for eczema: Management of Atopic Dermatitis Steven R. Feldman, |
biologic therapy for eczema: Management of Psoriasis Nikhil Yawalkar, 2009 Treatments for psoriasis, besides affecting the skin, may be associated with various comorbidities (for instance, depression, psoriatic arthritis, Crohn's disease and, in severe psoriasis, metabolic syndrome and cardiovascular diseases), which often presents a therapeutic challenge to physicians.Written by renowned experts, this volume gives a comprehensive overview of psoriasis and its various comorbidities. It describes the treatment modalities for mild and moderate-to-severe psoriasis, including topical, phototherapeutic and conventional systemic treatments (e.g. acitretine, methotrexate and cyclosporine), as well as biological therapies (e.g. alefacept, efalizumab, etanercept, adalimumab and infliximab). The chapters on biological therapies focus on key safety issues. Further chapters focus on such topics as the management of childhood psoriasis and psoriasis in distinctive locations, such as the scalp, face, flexures, palm/soles and nails. Finally, future therapeutic modalities, with the focus on small molecules and potential biological therapies, are discussed.This publication will make significant reading to dermatologists and all physicians dealing with psoriasis, such as general practitioners, psychiatrists, rheumatologists, cardiologists and diabetologists. |
biologic therapy for eczema: Handbook of Atopic Eczema Thomas Ruzicka, Johannes Ring, Bernhard Przybilla, 2013-03-09 State-of-the-art review on atopic eczema, one of the most common skin diseases today. This multi-authored handbook covers all aspects relevant for physicians from various disciplines. |
biologic therapy for eczema: Moderate to Severe Psoriasis John Koo, Jashin Wu, Alice Gottlieb, Ethan Levin, Argentina Leon, 2014-03-18 Written by experts in the dermatology field, this new fourth edition of Moderate-to-Severe Psoriasis discusses the current use of biologics and other pharmacologic and phototherapy treatments for moderate-to-severe psoriasis. Illustrated with high quality color figures, this standalone text emphasizes safe and effective treatments for the psoriasis |
biologic therapy for eczema: History of Allergy K.-C. Bergmann, J. Ring, 2014-05-27 The prevalence of allergic diseases has increased dramatically over recent decades, both in terms of the number of sufferers and the number of allergies. This is a trend that has frequently been referred to as 'the epidemic of the 21st century'. As described in ancient texts, allergies have been known for over 2,000 years, but the term 'allergy' was only coined at the beginning of the 20th century when doctors began to understand their pathophysiological basis. This book presents a detailed and varied historical overview of the field of allergology. Beginning with insights on allergy from antiquity to the 20th century and the development of the associated terminology, it compiles historical reflections on the understanding of the most common allergic diseases. Important milestones in the discovery of mechanisms of allergy are described, followed by historical accounts of the detection of allergens such as pollen, dust mites, peanuts and latex, and of environmental influences such as pollution and the relationship between farmers and their environment. Several chapters illustrate the progress made in allergy management to date. Particular highlights of this book are the personal reflections of and interviews with a number of pioneers of allergy, including F. Austen, J. Bienenstock, K. Blaser, A. de Weck, A.W. Frankland, K. Ishizaka, and many more. Concluding with portrayals of allergy societies and collections, as well as being supplemented by two films, this book represents a veritable treasure trove of fascinating and richly illustrated information. Not only researchers, physicians and medical historians, but also students and even non-scientists will find History of Allergy a scientific adventure well worth reading. |
biologic therapy for eczema: Exacerbating Factors in Atopic Eczema III Prof. Dr. Bilal Semih Bozdemir, Dietary modifications are frequently considered in atopic eczema management, especially in pediatric populations where food allergies may contribute to flaring. While the relationship between diet and eczema is complex, it is essential to assess each patient's dietary history and perform appropriate allergy testing, if warranted. Patients should be made aware that elimination diets can lead to significant dietary deficiencies if not managed correctly. When allergies are identified, collaboration with a nutritionist or dietitian can yield a balanced diet while managing eczema effectively. |
biologic therapy for eczema: Ethnic Dermatology Ophelia E. Dadzie, Antoine Petit, Andrew F. Alexis, 2013-01-02 ETHNIC DERMATOLOGY Principles and Practice Richly pigmented skin is the most common skin type internationally Historically, dermatology has focused on white skin. But rich pigmentation can lead to differences in presentation, disease course and outcome, and reaction to treatment. Some dermatologic conditions are seen either predominantly or exclusively in richly pigmented skin. Ethnic Dermatology: Principles and Practice provides a practical approach to the dermatology of nonwhite skin. Written from a global perspective to include Asian, African-Caribbean and North African skin types, it covers all the bases of dermatology including: Grading scales in dermatologic disease Pediatric dermatology Dermatology and systemic disease Drug eruptions Hair and scalp disorders Cosmetic dermatology. With a central focus on practical action from an international cast of authors, Ethnic Dermatology: Principles and Practice gives you the clinical tools you need when skin color matters. |
biologic therapy for eczema: Adverse Reactions to Biologics L. Puig, W. Gulliver, 2017-11-07 In many areas of medicine physicians still face the great challenge of finding therapies that will meet the patients’ needs. In dermatology the challenge has arisen on multiple fronts through advances in the understanding of the immunopathogenesis of many inflammatory and malignant cutaneous disorders. Breakthroughs, combined with significant developments in targeted immunotherapy, have resulted in improved outcomes as these newer therapies are being used for both approved indications and as off-label therapies for various chronic inflammatory skin disorders and many forms of skin cancer. In the expectation that by truly understanding the safety profile of these targeted therapies patients’ outcomes will be significantly improved, this book offers insights into topics such as adverse reactions, infectious complications and the perioperative use of biologics in psoriasis, immunogenicity of biologic therapies, paradoxical reactions, safety of biologics used to treat autoimmune bullous diseases and primary cutaneous lymphomas, adverse reactions and skin manifestations of therapies targeting melanoma and non-melanoma skin cancer and other neoplastic diseases. Eminent researchers with extensive clinical experience have contributed to this publication, providing an in-depth overview of the latest knowledge in this field. |
biologic therapy for eczema: Middleton's Allergy Essentials E-Book Robyn E O'Hehir, Stephen T Holgate, Aziz Sheikh, 2015-12-09 For decades, health care practitioners have relied on Middleton’s Allergy as their go-to reference for comprehensive information on allergic disorders. Now Middleton’s Allergy Essentials, by Drs. Robyn E. O'Hehir, Stephen T. Holgate, and Aziz Sheikh, offers a concise resource that’s both easily accessible and highly authoritative. Perfect for clinicians in primary and secondary care settings, this practical volume covers what is most useful in your daily practice, with a strong emphasis on disease diagnosis and management. A practical approach to evaluation, differential diagnosis, and treatment of allergic disorders, focused specifically on what the non-specialist needs to know for everyday practice. Each chapter begins with a handy summary of key concepts to help you quickly identify important information. Coverage of today’s hot topics includes asthma, drug allergies, food allergies and gastrointestinal disorders, anaphylaxis, atopic dermatitis, and allergic contact dermatitis. Concise sections on mechanisms are included where relevant, keeping you up to date with this rapidly evolving field. Authored by the same internationally recognized experts that produce Middleton’s Allergy, the definitive text in the field. Ideal for physicians, residents, general and family practitioners, nurse practitioners, primary care doctors, hospitalists, general internists – anyone who is called upon to make effective diagnostic and treatment decisions regarding allergic disorders. |
biologic therapy for eczema: Global Report on Psoriasis World Health Organization, 2016-02-15 This WHO Global report on psoriasis brings the public health impact of psoriasis into focus. The report is written to help raise awareness of the range of ways that psoriasis can affect peoples' lives. It intends to empower policy-makers with practical solutions to improve the health care and social inclusion of people living with psoriasis in their populations. The report highlights that much of the suffering caused by this common and complex disease can be avoided. Improving access to early diagnosis and appropriate treatment for psoriasis requires universally accessible health-care systems that provide people-centered care for patients with complex, lifelong conditions. Governments also have a key role to play in seeking to address the unnecessary social consequences of psoriasis by the challenging the myths and behaviors that lead to the exclusion of patients from healthcare settings and daily life. |
biologic therapy for eczema: Exacerbating Factors in Atopic Eczema II Prof. Dr. Bilal Semih Bozdemir, Exacerbating Factors in Atopic Eczema II Introduction Epidemiology of Atopic Eczema Etiology and Pathogenesis of Atopic Eczema Role of Genetics in Atopic Eczema Environmental Triggers of Atopic Eczema Allergens and Atopic Eczema Food Allergies and Atopic Eczema Irritants and Atopic Eczema Stress and Atopic Eczema Hormonal Factors in Atopic Eczema Infections and Atopic Eczema Skin Microbiome and Atopic Eczema Climate and Atopic Eczema Pollution and Atopic Eczema Smoking and Atopic Eczema Obesity and Atopic Eczema Medications and Atopic Eczema Comorbidities and Atopic Eczema Psychological Factors in Atopic Eczema Impact of Sleep Disturbance on Atopic Eczema Role of the Epidermal Barrier in Atopic Eczema Immune Dysregulation in Atopic Eczema Filaggrin Mutations and Atopic Eczema Cytokine Profiles in Atopic Eczema Th2 and Th17 Cells in Atopic Eczema Innate Immune Responses in Atopic Eczema Epigenetic Factors in Atopic Eczema Role of the Gut Microbiome in Atopic Eczema Biomarkers for Atopic Eczema Diagnostic Challenges in Atopic Eczema Severity Assessment in Atopic Eczema Treatment Approaches for Atopic Eczema Topical Therapies in Atopic Eczema Systemic Therapies in Atopic Eczema Biologic Therapies in Atopic Eczema Emerging Therapies for Atopic Eczema Preventive Strategies for Atopic Eczema Impact of Atopic Eczema on Quality of Life Patient Education and Self-Management Multidisciplinary Approach to Atopic Eczema Future Directions in Atopic Eczema Research Conclusion and Key Takeaways |
biologic therapy for eczema: Polymeric Gels Kunal Pal, Indranil Banerjee, 2018-06-15 Polymeric Gels: Characterization, Properties and Biomedical Applications covers the fundamentals and applications of polymeric gels. Particular emphasis is given to their synthesis, properties and characteristics, with topics such as natural, synthetic, and smart polymeric gels, medical applications, and advancements in conductive and magnetic gels presented. The book covers the basics and applications of hydrogels, providing readers with a comprehensive guide on the types of polymeric gels used in the field of biomedical engineering. - Provides guidance for decisions on the suitability and appropriateness of a synthetic route and characterization technique for particular polymeric networks - Analyzes and compares experimental data - Presents in-depth information on the physical properties of polymeric gels using mathematical models - Uses an interdisciplinary approach to discuss potential new applications for both established polymeric gels and recent advances |
biologic therapy for eczema: Biologics for the Treatment of Allergic Diseases, An Issue of Immunology and Allergy Clinics of North America, E-Book Lanny J. Rosenwasser, 2020-10-15 This issue of Immunology and Allergy Clinics, guest edited by Dr. Lanny Rosenwasser, will provide up-to-date clinical concepts regarding Biologics for the Treatments of Allergic Conditions. Articles in this outstanding issue include: Allergic Rhinitis/CRS/Polyposis, Eosinophilic Asthma, Pediatric Asthma, Severe Asthma, ACOS/COPD, Food Allergy, Atopic Dermatitis, Chronic Urticaria, Anaphylaxis, Drug Allergy, Cell Disorders, Biologics and Immunotherapy, and much more. |
biologic therapy for eczema: Human Herpesviruses Ann Arvin, Gabriella Campadelli-Fiume, Edward Mocarski, Patrick S. Moore, Bernard Roizman, Richard Whitley, Koichi Yamanishi, 2007-08-16 This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments. |
biologic therapy for eczema: Immune Rebalancing Diana Boraschi, Giselle Penton-Rol, 2016-01-25 Immune Rebalancing: The Future of Immunosuppression summarizes the most promising perspectives of immunopharmacology, in particular in the area of immunosuppression by considering molecular pathways, personalized medicine, microbiome and nanomedicine. Modulation of immune responses for therapeutic purposes is a particularly relevant area, given the central role of anomalous immunity in diseases. These diseases vary from the most typically immune-related syndromes (autoimmune diseases, allergy and asthma, immunodeficiencies) to those in which altered immunity and inflammation define the pathological outcomes (chronic infections, tumours, chronic inflammatory and degenerative diseases, metabolic disorders, etc. - Visits immunosuppression from a modern point of view of signalling mechanisms at the light of the current knowledge of signalling mechanisms and regulatory networks allows the reader to formulate new ideas and concepts on how to use immunosuppression the therapeutic purposes - Encourages researchers to engage into exploring the field of pharmacological modulation of immune responses in depth, and with the new knowledge and tools available, designs more effective therapeutic strategies to autoimmune and inflammatory diseases, cancer, degenerative diseases and infections - Examines the link between molecular pathways associated to immune-suppression and the new immunopharmacology approaches - Provides information on the new strategies for drug development in this field - Considers the role of microbes in the development of the mammalian immune system and immune responses, which will widen the reader's strategy for addressing therapeutic immune modulations |
biologic therapy for eczema: Immunology of the Skin Kenji Kabashima, 2016-03-10 This book reviews the role of each cell subset in the skin, providing the basics for understanding skin immunology and the mechanisms of skin diseases. The skin is one of the immune organs and is continually exposed to foreign antigens and external stimuli that must be monitored and characterized for possible elimination. Upon exposure to foreign antigens, the skin can elicit a variety of immune responses in harmony with skin components that include keratinocytes, dendritic cell subsets, mast cells, basophils, fibroblasts, macrophages, gamma-delta T cells, neutrophils, myeloid-derived suppressor cells, vascular and lymphatic cells, hair follicles, platelets, and adipose tissues, among others. In the past 10 years, knowledge of immunology has expanded drastically in areas such as innate immunity (Toll-like receptors, C-type lectins), and host defenses to bacteria and viruses, and this increased knowledge has led to the development of more effective treatment of psoriasis and other skin diseases. This book provides updates on the mechanisms of skin diseases including contact dermatitis, atopic dermatitis, psoriasis, urticaria, drug eruption, bullous diseases, anaphylaxis, graft-versus-host disease, rosacea, lymphoma, photodermatology, and collagen vascular diseases. Understanding the basics of skin immunology will help clinicians and dermatologists use new therapeutics such as biologics efficiently. Serving as an intermediary between basic science and clinical medicine, this book gives readers the opportunity to understand and marvel at the mystery and fascination of skin immunology. |
biologic therapy for eczema: The Calm Skin Guide Jae Rance, Amber Hatch, 2024-04-11 A parent's eczema care guide to soothe the itch and calm your child Eczema affects 1 in 5 children, causing itchy, sensitive, easily-damaged skin that flares-up painfully. The Calm Skin Guide offers an overview of all the treatment approaches on offer, giving you everything you need to formulate your own management plan for your child, and the tools to adapt when things change. It includes clear guidance on: - Eczema and the itch-scratch cycle - Doctor and pharmacy-based treatments, including emollients, steroids and antihistamines - Alternative treatments, how to assess them and how to use them - Identifying triggers in the home like dust, humidity, skincare products, detergents and foods - The relationship between eczema, asthma and allergies, and how to manage these conditions together - An emergency flare-up chapter - what to do first With tips on washing and laundry routines, practical ideas for ensuring comfortable, itch-free sleep, and guidance from GPs and dermatologists, here is friendly, research-based advice to help you keep your child's eczema - and the distress resulting from it - calm, soothed and under control. |
biologic therapy for eczema: Chemical and Biological Terrorism Institute of Medicine, Committee on R&D Needs for Improving Civilian Medical Response to Chemical and Biological Terrorism Incidents, 1999-03-12 The threat of domestic terrorism today looms larger than ever. Bombings at the World Trade Center and Oklahoma City's Federal Building, as well as nerve gas attacks in Japan, have made it tragically obvious that American civilians must be ready for terrorist attacks. What do we need to know to help emergency and medical personnel prepare for these attacks? Chemical and Biological Terrorism identifies the R&D efforts needed to implement recommendations in key areas: pre-incident intelligence, detection and identification of chemical and biological agents, protective clothing and equipment, early recognition that a population has been covertly exposed to a pathogen, mass casualty decontamination and triage, use of vaccines and pharmaceuticals, and the psychological effects of terror. Specific objectives for computer software development are also identified. The book addresses the differences between a biological and chemical attack, the distinct challenges to the military and civilian medical communities, and other broader issues. This book will be of critical interest to anyone involved in civilian preparedness for terrorist attack: planners, administrators, responders, medical professionals, public health and emergency personnel, and technology designers and engineers. |
biologic therapy for eczema: Evidence-Based Dermatology Michael Bigby, Andrew Herxheimer, Luigi Naldi, Berthold Rzany, Robert Dellavalle, Yuping Ran, Masutaka Furue, 2014-06-05 Be sure your skin-care treatments have strong evidential support Evidence-based Dermatology, Third Edition takes a unique approach to clinical dermatology by emphasising use of only the highest quality available evidence when treating people with skin diseases. Beginning with a toolbox introduction to the practice of evidence-based dermatology, it then covers the application of evidence for dermatological treatments across a wide range of ailments, including: • Common inflammatory skin diseases • Skin cancer, moles and actinic keratoses • Infective skin disease, exanthems and infestations • Disorders of pigmentation In addition, many of the rarer skin disorders are also included so as to provide comprehensive coverage of the topic. World-leading experts in dermatology follow a clinical approach for each disease, and as well as providing their expert guidance on the description and diagnosis of dermatologic disorders, they also discuss common dilemmas that clinicians face when considering the best approach to patient management. ‘Key Points’ accompany each chapter to provide a quick review of the most important points. Clinically oriented and practically focused, Evidence-based Dermatology ensures that your treatments are entirely patient-focused and fully supported by the very latest medical evidence. |
biologic therapy for eczema: Biologics in Allergic/Immunologic Conditions, An Issue of Immunology and Allergy Clinics of North America Flavia Hoyte, 2024-10-14 In this issue of Immunology and Allergy Clinics, guest editor Dr. Flavia Hoyte brings her considerable expertise to the topic of Biologics in Allergic/Immunologic Conditions. Top experts provide an overview of the state of biologic treatments for autoimmune and allergic conditions including asthma, COPD, food allergies, atopic dermatitis; and more. - Contains 13 relevant, practice-oriented topics including current and emerging biologics in CSU; biologics in AERD and ABPA; and multiple articles on biologics in asthma, including the role of biomarkers, the potential to achieve clinical remission, real-world studies, emerging biologics; and more. - Provides in-depth clinical reviews on biologics in allergic/immunologic conditions, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews. |
biologic therapy for eczema: New Trends in Allergy and Atopic Eczema Johannes Ring, U. Darsow, Heidrun Behrendt, 2012 Allergy and allergic diseases have increased in prevalence worldwide during the last decade. Relevant determinants influencing the development of allergic inflammation come from the environment and are either enhancing (e.g. environmental pollutants both indoors and outdoors) or protective (e.g. parasite infestations causing early stimulation of the immune system). In spite of considerable progress in experimental allergology and immunology, there is still a great discrepancy between theoretical knowledge and practical performance in the routine treatment of patients with allergies. The development of new therapeutic and preventive strategies for the future management of allergy is dependent on a better understanding of the pathomechanisms and molecular pathways involved. Based on an international symposium, this volume summarizes the latest findings in epidemiology, pathophysiology, and clinical aspects of allergic diseases such as asthma, food allergy, and, especially, atopic eczema. Risk factors for the development of allergies and novel treatment strategies are carefully evaluated. This update is essential reading for anyone interested in allergy: doctors working in the clinical fields of dermatology, pneumology, internal medicine, pediatrics, ENT, epidemiology and public health, as well as researchers in molecular genetics, immunobiology, food and nutrition sciences, and pharmacology.--Publisher's description. |
biologic therapy for eczema: Itch E. Carstens, Tasuku Akiyama, 2014-02-25 Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain. Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer. Composed of contributions from distinguished researchers around the world, the book explores topics such as: Neuropathic itch Peripheral neuronal mechanism of itch The role of PAR-2 in neuroimmune communication and itch Mrgprs as itch receptors The role of interleukin-31 and oncostatin M in itch and neuroimmune communication Spinal coding of itch and pain Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment. |
biologic therapy for eczema: Textbook of Hand Eczema Ali Alikhan, Jean-Marie Lachapelle, Howard I. Maibach, 2014-07-08 Hand eczema is a major complaint worldwide and a frequent occupational disorder. This book provides a comprehensive and detailed overview of the classification, etiology, diagnosis, prevention, and therapy of hand eczema. It is innovative, up to date, and practical. The links with particular occupations are explained, the various diagnostic tests are presented, and the role of different topical and systemic treatments is clearly described. The authors are world leaders in the field. The Textbook of Hand Eczema reflects a new era in hand dermatitis and will be invaluable for all who deal with the condition in their clinical practice. |
biologic therapy for eczema: A practical text-book of infection, immunity and biologic therapy, with sp John A. Kolmer, 1923 |
biologic therapy for eczema: Contact Dermatitis Peter J. Frosch, 2006 Accompanying CD-ROM includes all clinical photographs and important diagrams--p. [vii]. |
biologic therapy for eczema: A Practical Text-book of Infection, Immunity and Biologic Therapy John Albert Kolmer, 1923 |
biologic therapy for eczema: Photodermatology Henry W. Lim, Herbert Honigsmann, John L. M. Hawk, 2007-02-01 Covering the entire array of photodermatological topics necessary to stand at the head of this burgeoning discipline, this source contains expertly written chapters that offer recommendations and guidelines from opinion-forming international authorities. Reviewing the entire range of photodermatoses, as well as the management, treatment, i |
biologic therapy for eczema: Food Protein Induced Enterocolitis (FPIES) Terri Faye Brown-Whitehorn, Antonella Cianferoni, 2019-08-20 This unique book is a first-of-its-kind resource, comprehensively guiding readers through the epidemiology, pathophysiology, recent diagnostic criteria, and management options for patients with Food Protein-Induced Enterocolitis Syndrome (FPIES). Food-Protein Induced Enterocolitis Syndrome: Diagnosis and Management opens with a historical perspective of this condition, before moving into discussions of epidemiology and pathophysiology. FPIES can be difficult to diagnose as the symptoms overlap with multiple other conditions, and so clear differential diagnosis will be reviewed for both chronic FPIES, as well as acute FPIES. Later chapters are case-based, providing detailed multiple perspectives on the diagnosis and management of FPIES in patients with varying complicating factors and severity. Later chapters will tackle issues of quality of life in patient care, nutritional management for patients, and discussing working with parents and families to improve communication and at-home care. Parents, families and caregivers will also find chapters useful and relatable. A final chapter will look to the future of FPIES, addressing new research, guidelines, and implications for clinicians working with pediatric patients with FPIES, and for their families. Concise and practical, this book will be an ideal reference for allergists, pediatricians, family practice clinicians, gastroenterologists, nutritionists, and all other health care providers who encounter FPIES, and assist them in providing up-to-date, quality care for pediatric patients affected by this condition. |
biologic therapy for eczema: Atopic Dermatitis: New Insights for the Healthcare Professional: 2013 Edition , 2013-07-22 Atopic Dermatitis: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Additional Research in a concise format. The editors have built Atopic Dermatitis: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Additional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Atopic Dermatitis: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
biologic therapy for eczema: Skin Barrier Function T. Agner, 2016-02-04 Although a very fragile structure, the skin barrier is probably one of the most important organs of the body. Inward/out it is responsible for body integrity and outward/in for keeping microbes, chemicals, and allergens from penetrating the skin. Since the role of barrier integrity in atopic dermatitis and the relationship to filaggrin mutations was discovered a decade ago, research focus has been on the skin barrier, and numerous new publications have become available. This book is an interdisciplinary update offering a wide range of information on the subject. It covers new basic research on skin markers, including results on filaggrin and on methods for the assessment of the barrier function. Biological variation and aspects of skin barrier function restoration are discussed as well. Further sections are dedicated to clinical implications of skin barrier integrity, factors influencing the penetration of the skin, influence of wet work, and guidance for prevention and saving the barrier. Distinguished researchers have contributed to this book, providing a comprehensive and thorough overview of the skin barrier function. Researchers in the field, dermatologists, occupational physicians, and related industry will find this publication an essential source of information. |
biologic therapy for eczema: Color Atlas and Text of Obstetric and Gynecologic Dermatology Martin M. Black, Marilynne McKay, Peter R. Braude, 1995 Correct diagnosis in dermatology depends largely on the identification and interpretation of clinical signs. The book is written by an international team of dermatologists, obstetricians and gynecologists and is the only comprehensive obstetric and gynecologic dermatology atlas covering evaluation, diagnosis and management. The obstetric content includes skin diseases and manifestations of systemic disease, which have an effect on the reproductive system, and the impact of pregnancy on the skin. Normal physiologic changes in the skin in pregnancy are also covered, along with the effects of vulvar viral disease and connective tissue disease on pregnancy. The second half of the book is devoted to discussing the many facets of vulvar dermatoses. The many updates and changes make the book accessible for the non-dermatologist reader. |
biologic therapy for eczema: Health Care Provision and Patient Mobility Rosella Levaggi, Marcello Montefiori, 2013-12-11 Patient mobility across Europe is markedly increasing and new generations will actively ask to be treated by the health-care system that best meets their needs. At a political level, the EU issued the EU Directive no. 24/2011/CE of 9th March 2011 concerning the application of patients’ rights in cross-border health care and has contributed to improving the level of freedom of choice for the European citizen, but it does not seem to have increased actual patient mobility across Europe. Freedom to choose is necessary to grant the people of Europe the same access to public-sector health-care services. The latter is a key instrument for an efficiently functioning “single market” ensuring real mobility within the EU. The aim of this book is to study the current European health care market and discuss the hypothesis of a European right of citizenship with reference to health-care services. It examines patients' mobility from several perspectives: determinants of patient mobility, governance of cross-border mobility at EU level as concerns patients and health-care professionals, policy implications, and case studies. It is intended for health researchers, decision-makers and professionals concerned with health-care provision and patient mobility. The goal is to provide, through scientific and methodological rigor, new informative tools useful for the implementation of new policies in the health-care sector in order to implement effective health-care integration in the European Union. |
biologic therapy for eczema: Psychodermatology in Clinical Practice Anthony Bewley, Peter Lepping, Ruth Taylor, 2021-06-03 This book represents a simple, practical resource for all healthcare professionals working with dermatological patients with psychological aspects to their disease. The emphasis is on effective guidance rather than exhaustive case reviews, providing readers with a manual on the appropriate way to approach management of the patient in each case. Comprehensive in coverage, but concise in its delivery of information, Psychodermatology in Clinical Practice presents an idealized approach to management of psychodermatology patients within a global perspective, and provides practical tools to aid assessment of patients and in the decision-making process. It is suitable for dermatologists, psychiatrists and psychologists, dermatology nursing staff, primary care physicians and pediatricians. |
Electrochemical Instruments Manufacturer / BioLogic
Trusted for over 40 years by academic and industrial organizations worldwide, BioLogic measurement instruments, including potentiostats, battery cyclers, impedance analyzers, …
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BioLogic manufactures a variety of robust and user-friendly, potentiostats for diverse applications, from single-channel potentiostats to bipotentiostats to multichannel potentiostats.
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BioLogic ® offers a comprehensive line-up of battery cyclers, designed to support every stage of the battery development cycle through two complementary instrument ranges: Premium and …
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Details of BioLogic's spectrometer solutions: circular dichroism, High throughput CD Microplate spectropolarimeters and pump-probe spectrometers
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Energy-specific functionality unique to BioLogic includes: Fast CCCV shift (constant current, constant voltage) Stack mode (follow individual elements in the pack) BCD (Battery capacity …
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This package offers an array of tools that enable seamless integration with proprietary software, giving users precise control over their BioLogic Potentiostat/Galvanostat instruments. Key …
Paradoxical eczema in patients with psoriasis receiving …
agents, and discontinuation or switch of biologic therapy. Two patients had persis-tent eczema and psoriasis despite discontinuation of all biologic therapies. Despite atopic eczema (AE) and …
Dupilumab factsheet - Irish Skin Foundation
Jul 13, 2020 · of atopic eczema. If you think of a chemical messenger such as IL-4 as a key, and a cell receptor as a lock, a biologic drug works in a similar way to fixing a coin over the keyhole …
Recent Advances in the Diagnosis and Management of …
Subsequent developments in biologic therapy have led to the introduction of interleukin-17 (IL-17) inhibitors (e.g., secukinumab, ixekizumab) and interleukin-23 (IL-23) inhibitors ... eczema …
Upadacitinib (RINVOQ) in Atopic Dermatitis Criteria for Use …
Sep 12, 2024 · Within 2 weeks of starting upadacitinib therapy, determination of severity by either a Gestalt Assessment (GA) of “moderate” or “severe” OR Eczema Area and Severity Index …
Light Therapy for Psoriasis and Eczema - AAPC
Light Therapy for Psoriasis and Eczema Policy Number: 2.01.47 Last Review: 5/2014 Origination: 5/2006 Next Review: 5/2015 Policy Blue Cross and Blue Shield of Kansas City (Blue KC) will …
Dual biologic therapy with Omalizumab and Dupilumab for …
eczema (1). Treatment outcomes of these conditions and quality of life have significantly improved with the introduction of targeted biologic therapies, specifically omalizumab for asthma and …
TERAPÊUTICA BIOLÓGICA NO ECZEMA ATÓPICO
BIOLOGIC THERAPY IN ATOPIC ECZEMA ABSTRACT – Atopic eczema is a common inflammatory skin disease, affecting up to 20% of children and 3% of adults in industrialized …
Interleukin-4 (IL-4) Inhibitor Prior Authorization with Quantity …
Patient response to biologic therapy should be evaluated 4 months after initiating therapy, and the patient should be re-evaluated every 3 to 6 months. If response is ... Atopic dermatitis (AD), …
Research Letters M CAD ERMATOL ECEMBER - Journal of the …
biologic therapy To the Editor: The development of biologic agents has revolutionized treatment for immune-mediated inflammatory diseases.1 A cutaneous complication infrequently reported …
Short-Term Efficacy of Biologic Therapies in Moderate-to
The use of biologic therapy has revolutionized the management of moderate-to-severe psoriasis offering healthcare providers and patients with a multitude of highly effective and tolerable …
Biologics and biosimilar treatment for skin conditions
moderate to severe Hidradenitis Suppurativa or eczema, can have biologic or biosimilar treatment. The National Institute for Health and Care Excellence (NICE) gives information to …
January 9, 2025 Long Island Dermatologist Details New …
Adbry is a new biologic therapy specifically developed for patients with moderate to severe atopic dermatitis (eczema). The treatment is a monoclonal antibody that neutralizes interleukin-13 (IL …
Common Medications for Eosinophilic Esophagitis (EoE)
Biologic therapy Dupilumab (Dupixent®) What are the benefits of biologic therapy? • It lowers inflammation in the esophagus and improves symptoms of EoE. It is also used to treat children …
Treatment Pathway for Moderate to Severe Atopic Dermatitis …
the non-biologic systemic therapies listed This pathway is only applicable to adult patients who have moderate to severe atopic dermatitis. This is defined as: • An Eczema Area and Severity …
Biologic Therapy for Atopic Dermatitis: Moving Beyond the …
Key words: Atopic dermatitis; Eczema; Comorbidities; Immune dysregulation; Biologics; Dupilumab Biologic therapy for atopic dermatitis (AD) represents an exciting advance in the …
UNDERSTANDING THE LIVED EXPERIENCE OF ECZEMA
of eczema and reduce burden of disease; equip medical practices for a new era in eczema care; promote new models of care; support high-value/high-yield research projects; and, ... the first …
Clinical Protocol Treatment Pathway for Adults with Moderate …
Keywords Atopic dermatitis, eczema, biologic, dupilumab, tralokinumab, JAK inhibitor, JAKi, abrocitinib, baricitinib, upadacitinib, lebrikizumab Change History Date Change details, since …
© 2025 ReachMD Page 1 of 12
Clinicians Exchange, LLC and National Eczema Association. Prior to beginning the activity, please be sure to review the faculty and commercial support disclosure statements as well as …
Biologic Biologic therapy - Canadian Thoracic Society
reason (bad eczema, nasal polyps, etc.) Which patients with asthma should not receive a biologic? • Those who have not yet been assessed by a lung specialist or allergy ... patients …
JAK inhibitors in the treatment of atopic dermatitis - The …
May 15, 2021 · Key words: Atopic dermatitis, eczema, itch, therapy, JAK inhibitor Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disorder that affects 7% of adults …
New drug therapy for young children with severe eczema
New drug therapy for young children with severe eczema September 15 2022 Eczema, also known as atopic dermatitis, is a chronic condition that causes the ... A biologic therapy for very …
nemolizumab (Nemluvio®)
Member is not continuing therapy based off being established on therapy through samples, manufacturer coupons, or otherwise. If they have, initial policy criteria must be met for the …
UNDERSTANDING THE LIVED EXPERIENCE OF ECZEMA - AAFA
relatively limited use of other systemic treatments; the first biologic therapy approved for use in treating eczema, dupilumab (or Dupixent), was reported to be used currently by 10% of survey …
The Effect of Calcium Homeostasis and Immune Disorders on …
Jan 4, 2025 · Eczema is an inflammatory skin disorder with high prevalence in childhood. Eczema can lead to a negative impact on the patient, the family, and society. ... and developing a …
Current and Emerging Biologics for Atopic Dermatitis
moderate-to-severe AD participating in a trial of a biologic therapy, 85% reported problems with itch frequency, 41.5% reported itching 18 hours/day, 55% reported ... National Eczema …
Global Report on Atopic Dermatitis 2022 - eczemacouncil.org
Aug 13, 2022 · dermatitis is also known as ‘atopic eczema’, ‘neurodermatitis’, or just simply as ‘eczema’ (1, 3). Although the precise etiology has not been fully elucidated, there are many …
Less Can Be More: The Case for Extended Dosing Intervals in …
Less can be more: The case for extended dosing intervals in biologic therapy for AD Christian Vestergaard Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark ...
Joint Guidelines for the Management of Interruption of …
biologic drugs By: All clinicians and surgical pre-assessment staff involved in preparing patients for elective surgery For: Adults and Children with Rheumatological conditions requiring …
Letter from the Editor: Paradoxical reactions to biologics
biologic or a switch to a Janus kinase inhibitor.3 Conversely, paradoxical eczematous eruptions have been reported with biologic therapy for psoriasis.4 Brodalumab-induced eczematous …
Biologic medications for dermatological conditions
Biologic medicine or biologics, are an injectable medication. They are proteins that are made by or extracted from living cells like plant, fungal, or animal cells. Biologics are complex large …
STAY AHEAD OF ECZEMA WITH DUPIXENT
uncontrolled moderate-to-severe eczema. IQVIA National Source of Business (NSOB) data through 3/17/2023 A DIFFERENCE INSIDE AND OUT IS A BIOLOGIC THAT HELPS BLOCK …
Dermatology Specialist formulary list **Other indications for ...
Severe chronic hand eczema unresponsive to treatment with potent topical corticosteroids ; To be dispensed by a hospital pharmacy only. Monitoring is undertaken by the Dermatology Clinic. 8 …
Asthma Focused Follow-Up Visit For Defining Difficult To …
With SDM For Biologic Therapy . Asthma Visits In The Past 12 Months During This Office Visit Would You Like To Discuss Any Of The Following: ... q Eczema q Food allergy q GERD q …
Concurrent Atopic Dermatitis and Psoriasis Successfully …
fully treated with dual biologic therapy with dupilumab and gusel-kumab. Our case highlights the importance of considering coexisting AD and psoriasis in patients with treatment-resistant …
Topical calcineurin inhibitors factsheet (November 2023)
eczema is well controlled, topical steroids are stopped and TCIs are used twice a day, then reduced to once a . Topical calcineurin inhibitors factsheet National Eczema Society Helpline: …
The UK-Irish Atopic eczema Systemic TherApy Register A-STAR
Population: Children (no lower age cut off) and adults with atopic eczema (UK Working Party diagnostic criteria), starting on or switching to another systemic immuno-modulatory therapy …
IL-31: A new key player in dermatology and beyond - The …
atopic eczema, and represents a novel target for directed drug therapy. Regulation of immune responses and cellular differentiation and proliferation are recently elucidated effects of IL-31, …
Alitretinoin (Toctino): new oral retinoid for chronic hand eczema
of hand eczema of all severities is approximately 10 per cent but only around half of people affected seek medical help. 1 Chronic severe hand eczema, which may account for 5-7 per …
First eczema biologic debuts but price could restrict use
approved the first biologic therapy for atopic . dermatitis, the itchy skin condition better known as eczema. The drug is a human mono - clonal antibody called Dupixent (dupilumab)
EUROGUIDERM GUIDELINE ON ATOPIC EuroGuiDerm …
the impact of atopic eczema on the patient’s psychological wellbeing can be profound and require - specialist intervention. Whilst in most cases atopic eczema can be treated by a …
Upadacitinib as a treatment for co-existent allergic contact …
the development of eczema in patients receiving psoriasis biologics or development of de novo psoriasiform dermatitis in patients receiving dupilu-mab (Dupixent), which is an interleukin 4 …
010 Immunomodulators for Skin Conditions - Blue Cross Blue …
QCD - Quality Care Dosing (quantity limits policy #621B); ST – Step Therapy Biologic Agents for Skin Conditions Table 1. Documented FDA labeled diagnosis, AND 2. Meet the step therapy …
European guideline (EuroGuiDerm) on atopic eczema: part I …
ment and treatment of patients with atopic eczema (AE) of all severities and age groups. According to the scoping document, the objectives of the guideline are as follows: † To …
Biologics and Small Molecule Inhibitors: an Update in …
2017, dupilumab became the rst biologic approved for AD. Since this time, a surge in research has led to dozens more ... terms “atopic dermatitis,” “eczema,” “psoriasis,” “allergic ...
Nottinghamshire commissioning guidance for the treatment …
non-biologic systemic No Yes At the week 16 review has the patient achieved: • at least a 50% reduction in the Eczema Area and Severity Index score (EASI) from when treatment started …
Clinical Protocol Treatment Pathway for Adults with Moderate …
Aug 14, 2024 · Keywords Atopic dermatitis, eczema, biologic, dupilumab, tralokinumab, JAK inhibitor, JAKi, abrocitinib, baricitinib, upadacitinib, lebrikizumab ... or head and neck eczema). …
JAK-inhibitors as rescue therapy in dupilumab-refractory …
the use of adjunctive therapy. In fact, a single case report has shown a positive response to tofacitinib rescue therapy in a patient who was inadequately controlled with dupilumab …
This label may not be the latest approved by FDA. For current …
therapy. (1.7) RINVOQ is not recommended for use in combination with other JAK inhibitors, biologic DMARDs, or with potent immunosuppressants such as azathioprine and cyclosporine. …
Biologic and small-molecule therapy for treating moderate …
Jan 22, 2024 · Biologic and small-molecule therapy for treating moderate to severe atopic dermatitis: Mechanistic considerations Camille Rothenberg-Lausell, MS,a,b Jonathan Bar, ...
Biologic Versus Small Molecule Therapy for Treating …
Biologic Versus Small Molecule Therapy for Treating Moderate to Severe Atopic Dermatitis: Clinical Considerations Sneha Butala, MDa, Leslie Castelo-Soccio, MD, PhDb, Rishi Seshadri, …