Advertisement
| biotechnology and bioprocess engineering: Biochemical Engineering and Biotechnology Ghasem Najafpour, 2015-02-24 Biochemical Engineering and Biotechnology, 2nd Edition, outlines the principles of biochemical processes and explains their use in the manufacturing of every day products. The author uses a diirect approach that should be very useful for students in following the concepts and practical applications. This book is unique in having many solved problems, case studies, examples and demonstrations of detailed experiments, with simple design equations and required calculations. - Covers major concepts of biochemical engineering and biotechnology, including applications in bioprocesses, fermentation technologies, enzymatic processes, and membrane separations, amongst others - Accessible to chemical engineering students who need to both learn, and apply, biological knowledge in engineering principals - Includes solved problems, examples, and demonstrations of detailed experiments with simple design equations and all required calculations - Offers many graphs that present actual experimental data, figures, and tables, along with explanations |
| biotechnology and bioprocess engineering: Putting Biotechnology to Work National Research Council, Division on Earth and Life Studies, Commission on Life Sciences, Committee on Bioprocess Engineering, 1992-02-01 The ability of the United States to sustain a dominant global position in biotechnology lies in maintaining its primacy in basic life-science research and developing a strong resource base for bioprocess engineering and bioproduct manufacturing. This book examines the status of bioprocessing and biotechnology in the United States; current bioprocess technology, products, and opportunities; and challenges of the future and what must be done to meet those challenges. It gives recommendations for action to provide suitable incentives to establish a national program in bioprocess-engineering research, development, education, and technology transfer. |
| biotechnology and bioprocess engineering: Bioprocess Engineering Principles Pauline M. Doran, 1995-04-03 The emergence and refinement of techniques in molecular biology has changed our perceptions of medicine, agriculture and environmental management. Scientific breakthroughs in gene expression, protein engineering and cell fusion are being translated by a strengthening biotechnology industry into revolutionary new products and services. Many a student has been enticed by the promise of biotechnology and the excitement of being near the cutting edge of scientific advancement. However, graduates trained in molecular biology and cell manipulation soon realise that these techniques are only part of the picture. Reaping the full benefits of biotechnology requires manufacturing capability involving the large-scale processing of biological material. Increasingly, biotechnologists are being employed by companies to work in co-operation with chemical engineers to achieve pragmatic commercial goals. For many years aspects of biochemistry and molecular genetics have been included in chemical engineering curricula, yet there has been little attempt until recently to teach aspects of engineering applicable to process design to biotechnologists.This textbook is the first to present the principles of bioprocess engineering in a way that is accessible to biological scientists. Other texts on bioprocess engineering currently available assume that the reader already has engineering training. On the other hand, chemical engineering textbooks do not consider examples from bioprocessing, and are written almost exclusively with the petroleum and chemical industries in mind. This publication explains process analysis from an engineering point of view, but refers exclusively to the treatment of biological systems. Over 170 problems and worked examples encompass a wide range of applications, including recombinant cells, plant and animal cell cultures, immobilised catalysts as well as traditional fermentation systems.* * First book to present the principles of bioprocess engineering in a way that is accessible to biological scientists* Explains process analysis from an engineering point of view, but uses worked examples relating to biological systems* Comprehensive, single-authored* 170 problems and worked examples encompass a wide range of applications, involving recombinant plant and animal cell cultures, immobilized catalysts, and traditional fermentation systems* 13 chapters, organized according to engineering sub-disciplines, are groupled in four sections - Introduction, Material and Energy Balances, Physical Processes, and Reactions and Reactors* Each chapter includes a set of problems and exercises for the student, key references, and a list of suggestions for further reading* Includes useful appendices, detailing conversion factors, physical and chemical property data, steam tables, mathematical rules, and a list of symbols used* Suitable for course adoption - follows closely curricula used on most bioprocessing and process biotechnology courses at senior undergraduate and graduate levels. |
| biotechnology and bioprocess engineering: Bioprocess Engineering for a Green Environment V. Sivasubramanian, 2018-05-04 Bioprocess Engineering for a Green Environment examines numerous bioprocesses that are crucial to our day-to-day life, specifically the major issues surrounding the production of energy relating to biofuels and waste management. The nuance of this discussion is reflected by the text’s chapter breakdown, providing the reader with a fulsome investigation of the energy sector; the importance of third-generation fuels; and the application of micro- and macroalgae for the production of biofuels. The book also provides a detailed exploration of biocatalysts and their application to the food industry; bioplastics production; conversion of agrowaste into polysaccharides; as well as the importance of biotechnology in bio-processing. Numerous industries discharge massive amounts of effluents into our rivers, seas, and air systems. As such, two chapters are dedicated to the treatment of various pollutants through biological operation with hopes of achieving a cleaner, greener, environment. This book represents the most comprehensive study of bioprocessing—and its various applications to the environment—available on the market today. It was furthermore written with various researchers in mind, ranging from undergraduate and graduate students looking to enhance their knowledge of the topics presented to scholars and engineers interested in the bioprocessing field, as well as members of industry and policy-makers. Provides a comprehensive overview of bioprocesses that apply to day-to-day living. Is learner-centered, providing detailed diagrams for easy understanding. Explores the importance of biocatalysts and their applications to the food industry, as well as bioplastics production. Examines the unique capabilities of bioprocess engineering and its ability to treat various pollutants. . |
| biotechnology and bioprocess engineering: Bioprocess Engineering Kim Gail Clarke, 2013-10-31 Biotechnology is an expansive field incorporating expertise in both the life science and engineering disciplines. In biotechnology, the scientist is concerned with developing the most favourable biocatalysts, while the engineer is directed towards process performance, defining conditions and strategies that will maximize the production potential of the biocatalyst. Increasingly, the synergistic effect of the contributions of engineering and life sciences is recognised as key to the translation of new bioproducts from the laboratory bench to commercial bioprocess. Fundamental to the successful realization of the bioprocess is a need for process engineers and life scientists competent in evaluating biological systems from a cross-disciplinary viewpoint. Bioprocess engineering aims to generate core competencies through an understanding of the complementary biotechnology disciplines and their interdependence, and an appreciation of the challenges associated with the application of engineering principles in a life science context. Initial chapters focus on the microbiology, biochemistry and molecular biology that underpin biocatalyst potential for product accumulation. The following chapters develop kinetic and mass transfer principles that quantify optimum process performance and scale up. The text is wide in scope, relating to bioprocesses using bacterial, fungal and enzymic biocatalysts, batch, fed-batch and continuous strategies and free and immobilised configurations. - Details the application of chemical engineering principles for the development, design, operation and scale up of bioprocesses - Details the knowledge in microbiology, biochemistry and molecular biology relevant to bioprocess design, operation and scale up - Discusses the significance of these life sciences in defining optimum bioprocess performance |
| biotechnology and bioprocess engineering: Systems Biology and Synthetic Biology Pengcheng Fu, Sven Panke, 2009-08-13 The genomic revolution has opened up systematic investigations and engineering designs for various life forms. Systems biology and synthetic biology are emerging as two complementary approaches, which embody the breakthrough in biology and invite application of engineering principles. Systems Biology and Synthetic Biology emphasizes the similarity between biology and engineering at the system level, which is important for applying systems and engineering theories to biology problems. This book demonstrates to students, researchers, and industry that systems biology relies on synthetic biology technologies to study biological systems, while synthetic biology depends on knowledge obtained from systems biology approaches. |
| biotechnology and bioprocess engineering: Engineering Principles in Biotechnology Wei-Shou Hu, 2017-11-13 This book is a short introduction to the engineering principles of harnessing the vast potential of microorganisms, and animal and plant cells in making biochemical products. It was written for scientists who have no background in engineering, and for engineers with minimal background in biology. The overall subject dealt with is process. But the coverage goes beyond the process of biomanufacturing in the bioreactor, and extends to the factory of cell’s biosynthetic machinery. Starting with an overview of biotechnology and organism, engineers are eased into biochemical reactions and life scientists are exposed to the technology of production using cells. Subsequent chapters allow engineers to be acquainted with biochemical pathways, while life scientist learn about stoichiometric and kinetic principles of reactions and cell growth. This leads to the coverage of reactors, oxygen transfer and scale up. Following three chapters on biomanufacturing of current and future importance, i.e. cell culture, stem cells and synthetic biology, the topic switches to product purification, first with a conceptual coverage of operations used in bioseparation, and then a more detailed analysis to provide a conceptual understanding of chromatography, the modern workhorse of bioseparation. Drawing on principles from engineering and life sciences, this book is for practitioners in biotechnology and bioengineering. The author has used the book for a course for advanced students in both engineering and life sciences. To this end, problems are provided at the end of each chapter. |
| biotechnology and bioprocess engineering: Bioprocess Engineering Pau Loke Show, Chien Wei Ooi, Tau Chuan Ling, 2019-05-24 Bioprocess Engineering: Downstream Processing is the first book to present the principles of bioprocess engineering, focusing on downstream bioprocessing. It aims to provide the latest bioprocess technology and explain process analysis from an engineering point of view, using worked examples related to biological systems. This book introduces the commonly used technologies for downstream processing of biobased products. The covered topics include centrifugation, filtration, membrane separation, reverse osmosis, chromatography, biosorption, liquid-liquid separation, and drying. The basic principles and mechanism of separation are covered in each of the topics, wherein the engineering concept and design are emphasized. This book is aimed at bioprocess engineers and professionals who wish to perform downstream processing for their feedstock, as well as students. |
| biotechnology and bioprocess engineering: Cell Culture Bioprocess Engineering, Second Edition Wei-Shou Hu, 2020-03-06 This book is the culmination of three decades of accumulated experience in teaching biotechnology professionals. It distills the fundamental principles and essential knowledge of cell culture processes from across many different disciplines and presents them in a series of easy-to-follow, comprehensive chapters. Practicality, including technological advances and best practices, is emphasized. This second edition consists of major updates to all relevant topics contained within this work. The previous edition has been successfully used in training courses on cell culture bioprocessing over the past seven years. The format of the book is well-suited to fast-paced learning, such as is found in the intensive short course, since the key take-home messages are prominently highlighted in panels. The book is also well-suited to act as a reference guide for experienced industrial practitioners of mammalian cell cultivation for the production of biologics. |
| biotechnology and bioprocess engineering: Current Developments in Biotechnology and Bioengineering Sudhir P. Singh, Ashok Pandey, Guocheng Du, Sudesh Kumar, 2018-11-20 Current Developments in Biotechnology and Bioengineering: Synthetic Biology, Cell Engineering and Bioprocessing Technologies covers the current perspectives and outlook of synthetic biology in the agriculture, food and health sectors. This book begins with the basics about synthetic biology and cell engineering, and then explores this in more detail, focusing on topics like applications of synthetic biology, industrial bioprocesses, and future perspectives. Information on cell engineering is also presented, and manipulation in endogenous metabolic network is studied alongside advanced topics such as fine tuning of metabolic pathways, de novo biosynthetic pathway design, enzyme engineering targeted to improved kinetics and stability, and potential applications of the novel biological systems in bioprocess technology to achieve the production of value-added compounds with specific biological activities. - Assists in developing a conceptual understanding of synthetic biology and cellular and metabolic engineering. - Includes comprehensive information on new developments and advancements. - Lists applications of synthetic biology in agriculture, food, and health |
| biotechnology and bioprocess engineering: Advances in Bioprocess Engineering Enrique Galindo, Octavio R. Ramírez, 2013-04-17 Bioprocess engineering has played a key role in biotechnology, contributing towards bringing the exciting new discoveries of molecular and cellular biology into the applied sphere, and in maintaining established processes, some centuries-old, efficient and essential for today's industry. Novel developments and new application areas of biotechnology, along with increasing constraints in costs, product quality, regulatory and environmental considerations, have placed the biochemical engineer at the forefront of new challenges. This second volume of Advances in Bioprocess Engineering reflects precisely the multidisciplinary nature of the field, where new and traditional areas of application are nurtured by a better understanding of fundamental phenomena and by the utilization of novel techniques and methodologies. The chapters in this book were written by the invited speakers to the 2nd International Symposium on Bioprocess Engineering, Mazatlan, Mexico, September 1997. |
| biotechnology and bioprocess engineering: New Trends and Developments in Biochemical Engineering Thomas Scheper, 2004-01-29 With contributions by numerous experts |
| biotechnology and bioprocess engineering: Integrated Bioprocess Engineering Clemens Posten, 2024-07-01 Bioprocess engineering employs microorganisms to produce biological products for medical and industrial applications. The book covers engineering tasks around- the cultivation process in bioreactors including media design, feeding strategies, or cell harvesting. All aspects are described from the conceptual considerations to technical realization and provide insight by detailed explanations, drawings, formulas, and example processes. |
| biotechnology and bioprocess engineering: Bioprocess Engineering Shijie Liu, 2012-11-21 Bioprocess Engineering involves the design and development of equipment and processes for the manufacturing of products such as food, feed, pharmaceuticals, nutraceuticals, chemicals, and polymers and paper from biological materials. It also deals with studying various biotechnological processes. Bioprocess Kinetics and Systems Engineering first of its kind contains systematic and comprehensive content on bioprocess kinetics, bioprocess systems, sustainability and reaction engineering. Dr. Shijie Liu reviews the relevant fundamentals of chemical kinetics-including batch and continuous reactors, biochemistry, microbiology, molecular biology, reaction engineering, and bioprocess systems engineering- introducing key principles that enable bioprocess engineers to engage in the analysis, optimization, design and consistent control over biological and chemical transformations. The quantitative treatment of bioprocesses is the central theme of this book, while more advanced techniques and applications are covered with some depth. Many theoretical derivations and simplifications are used to demonstrate how empirical kinetic models are applicable to complicated bioprocess systems. - Contains extensive illustrative drawings which make the understanding of the subject easy - Contains worked examples of the various process parameters, their significance and their specific practical use - Provides the theory of bioprocess kinetics from simple concepts to complex metabolic pathways - Incorporates sustainability concepts into the various bioprocesses |
| biotechnology and bioprocess engineering: Bioprocess Engineering Principles Pauline M. Doran, 2013 |
| biotechnology and bioprocess engineering: Bioreaction Engineering Principles Jens Nielsen, John Villadsen, Gunnar Lidén, 2012-12-06 This is the second edition of the text Bioreaction Engineering Principles by Jens Nielsen and John Villadsen, originally published in 1994 by Plenum Press (now part of Kluwer). Time runs fast in Biotechnology, and when Kluwer Plenum stopped reprinting the first edition and asked us to make a second, revised edition we happily accepted. A text on bioreactions written in the early 1990's will not reflect the enormous development of experimental as well as theoretical aspects of cellular reactions during the past decade. In the preface to the first edition we admitted to be newcomers in the field. One of us (JV) has had 10 more years of job training in biotechnology, and the younger author (IN) has now received international recognition for his work with the hottest topics of modem biotechnology. Furthermore we are happy to have induced Gunnar Liden, professor of chemical reaction engineering at our sister university in Lund, Sweden to join us as co-author of the second edition. His contribution, especially on the chemical engineering aspects of real bioreactors has been of the greatest value. Chapter 8 of the present edition is largely unchanged from the first edition. We wish to thank professor Martin Hjortso from LSU for his substantial help with this chapter. |
| biotechnology and bioprocess engineering: Advances In Bio-processing Engineering Juming Tang, Harrison Xiusheng Yang, 2002-05-22 This book consists of peer-reviewed articles reporting on the latest developments in several food engineering and agricultural processing laboratories at US land-granted universities. The contributors are leading experts in their respective fields.The topics covered in the book include new food processing technologies (such as high voltage electric field processing and microwave sterilization/pasteurization), conversion of agricultural by-products into high quality refined cellulose or biodegradable plastics, and advances in machine vision inspection and sorting techniques for fruit and vegetable packaging lines. Each chapter begins with a general background review with important references, and ends with the latest results from each research laboratory. |
| biotechnology and bioprocess engineering: Advances in Bioprocess Engineering and Technology Doraiswami Ramkrishna, Subhabrata Sengupta, Sudipta Dey Bandyopadhyay, Avijit Ghosh, 2020-09-29 This book presents the select peer-reviewed proceedings of the International Conference on Advances in Bioprocess Engineering and Technology (ICABET 2020). The book covers all aspects of bioprocesses, especially related to fermentation technology, food technology, environmental biotechnology, and sustainable energy. Along with this primary theme, the focus is on recent advances in bioprocessing research such as biosensors, micro-reactors, novel separation techniques, bioprocess control, bio-safety, advanced techniques for waste to wealth generation, and nanobiotechnology. This contents are divided according to the major themes of the conference: (i) Fermentation Technology and Bioreactor, (ii) Food Pharmaceuticals and Health care, (iii) Environment and Agriculture, and (iv) Sustainable Energy. This book is intended to help students, researchers, and industry professionals acquire knowledge on innovative technologies and recent advancements in the field of bioprocess engineering and technology. |
| biotechnology and bioprocess engineering: New Products and New Areas of Bioprocess Engineering , 2003-06-30 Today, ergot alkaloids have found widespread clinical use and more than 50 formulations contain natural or semisynthetic ergot alkaloids. They are used in the treatment of uterine atonia, postpartum bleeding, migraine, orthostatic circulatory disturbances, senile cerebral insufficiency, hypertension, hyp- prolactinemia, acromegaly, and Parkinsonism. Recently, new therapeutic - plications have emerged, e.g., against schizophrenia and for therapeutic usage based on newly discovered antibacterial and cytostatic effects, immunomodu- tory and hypolipemic activity. The broad physiological effects of ergot alkaloids are based mostly on their interactions with neurotransmitter receptors on the cells. The presence of hidden structures'' resembling some important neu- humoral mediators (e.g., noradrenaline, serotonin, dopamine) in the molecules of ergot alkaloids could explain their interactions with these receptors [1]. Ergot alkaloids are produced by the filamentous fungi of the genus, Claviceps (e.g., Claviceps purpurea - Ergot, Mutterkorn). On the industrial scale these alkaloids were produced mostly by parasitic cultivation (field production of the ergot) till the end of the 1970s. Today this uneconomic method has been - placed by submerged fermentation. Even after a century of research on ergot alkaloids the search still continues for new, more potent and more selective ergot alkaloid derivatives |
| biotechnology and bioprocess engineering: Chemical and Bioprocess Engineering Shirish Sonawane, Y. Pydi Setty, Srinu Naik Sapavatu, 2015-04-15 Examining energy, environment, and sustainability from the chemical engineering point of view, this book highlights critical issues faced by chemical engineers and biochemical engineers worldwide. The book covers recent trends in chemical engineering and bioprocess engineering, such as CFD simulation, statistical optimization, process control, |
| biotechnology and bioprocess engineering: Biotransformations and Bioprocesses Mukesh Doble, Anil Kumar Kruthiventi, Vilas Ganjanan Gaikar, 2004-03-24 From the laboratory to full-scale commercial production, this reference provides a clear and in-depth analysis of bioreactor design and operation and encompasses critical aspects of the biocatalytic manufacturing process. It clarifies principles in reaction and biochemical engineering, synthetic and biotransformation chemistry, and biocell and enzy |
| biotechnology and bioprocess engineering: Tools and Applications of Biochemical Engineering Science K. Schügerl, A.-P. Zeng, 2003-07-01 This special volume Tools and Applications of Biochemical Engineering Science is dedicated to Professor Wolf-Dieter Deckwer on the occasion of his 60th bir- day. It was a great pleasure for me to act together with Professor Karl Schtigerl as volume editor and to present here a collection of 11 outstanding review articles written mainly by former students, associates, colleagues and friends of Wolf- Dieter Deckwer. The title of this special volume well reflects the research interests and sci- tific pursuit of Wolf-Dieter Deckwer during his more than 20 years’ work in the area of biochemical engineering, particularly during the last 15 years when he was the head of the Biochemical Engineering Division of GBF (German Nat- nal Research Center for Biotechnology). He has decisively pushed the devel- ment not only of software tools ranging from analytical means and mathe- tical models for monitoring and understanding cellular processes to gene expression systems for designing microorganisms, but also of hardware tools such as computer control systems, bioreaction and separation devices for eff- tively producing a variety of bioproducts on semi-production scale. New developments in some of these important tools in biochemical engineering are reviewed in articles included in this volume. Wolf-Dieter Deckwer was among the leading biochemical engineers who timely pointed out the necessity of applying these tools in an integrated manner for bioprocess development. By establishing Integrated Bioprocess Development as one of the GBF main - search topics as early as 1990 he also actively promoted this idea. |
| biotechnology and bioprocess engineering: Bioprocess Engineering: An Introductory Engineering and Life Science Approach Kim Gail Clarke, 2017-11-13 Biotechnology is an expansive field incorporating expertise in both the life science and engineering disciplines. In biotechnology, the scientist is concerned with developing the most favourable biocatalysts, while the engineer is directed towards process performance, defining conditions and strategies that will maximize the production potential of the biocatalyst. Increasingly, the synergistic effect of the contributions of engineering and life sciences is recognised as key to the translation of new bioproducts from the laboratory bench to commercial bioprocess. Fundamental to the successful realization of the bioprocess is a need for process engineers and life scientists competent in evaluating biological systems from a cross-disciplinary viewpoint. Bioprocess engineering aims to generate core competencies through an understanding of the complementary biotechnology disciplines and their interdependence, and an appreciation of the challenges associated with the application of engineering principles in a life science context. Initial chapters focus on the microbiology, biochemistry and molecular biology that underpin biocatalyst potential for product accumulation. The following chapters develop kinetic and mass transfer principles that quantify optimum process performance and scale up. The text is wide in scope, relating to bioprocesses using bacterial, fungal and enzymic biocatalysts, batch, fed-batch and continuous strategies and free and immobilised configurations. Details the application of chemical engineering principles for the development, design, operation and scale up of bioprocessesDetails the knowledge in microbiology, biochemistry and molecular biology relevant to bioprocess design, operation and scale upDiscusses the significance of these life sciences in defining optimum bioprocess performance |
| biotechnology and bioprocess engineering: Bioprocess Engineering Bjorn K. Lydersen, Nancy A. D'Elia, Kim L. Nelson, 1994-04-18 Divided into four sections, the first and third reflect the fact that there are two types of equipment required in the plant--one in which the actual product is synthesized or processed such as the fermentor, centrifuge and chromatographic columns; and the other that supplies support for the facility or process including air conditioning, water and waste systems. Part two describes such components as pumps, filters and valves not limited to a certain type of equipment. Lastly, it covers planning and designing the entire facility along with requirements for containment and validation of the process. |
| biotechnology and bioprocess engineering: Bioprocess Engineering Michael L. Shuler, Fikret Kargi, 2014 For Senior-level and graduate courses in Biochemical Engineering, and for programs in Agricultural and Biological Engineering or Bioengineering. This concise yet comprehensive text introduces the essential concepts of bioprocessing-internal structure and functions of different types of microorganisms, major metabolic pathways, enzymes, microbial genetics, kinetics and stoichiometry of growth and product information-to traditional chemical engineers and those in related disciplines. It explores the engineering principles necessary for bioprocess synthesis and design, and illustrates the application of these principles to modern biotechnology for production of pharmaceuticals and biologics, solution of environmental problems, production of commodities, and medical applications. |
| biotechnology and bioprocess engineering: Environmental Biotechnology and Cleaner Bioprocesses Gloria Sanchez, Elizabeth Hernandez, 2023-06-14 As we enter a new millennium, the environmental issues faced by both developing and industrialised nations are as pressing as ever. Environmental biotechnologies are increasingly being viewed as a major weapon against environmental damage. Cleaner production is part of this strategy and yet there is still widespread ignorance about this emerging technology. Environmental Biotechnology and Cleaner Bioprocesses provides this information at various levels, from introductory to advanced. The first section covers the development of cleaner bioprocesses within the framework of sustainable development. Aspects of environmental policy for small and medium businesses are then discussed using case studies to illustrate principles. The second section covers the recycling and treatment of organic waste, including the use of aquatic plants and microalgae for wastewater treatment and recovery of nutrients. Section three covers bioremediation technologies and finally, section four is dedicated to emerging cleaner bioprocesses and environmentally sound products. All chapters have been written and edited by leading authorities in the field. Students and professionals interested in environmental biotechnology and cleaner production will find the background information and detail they require in this one convenient source. |
| biotechnology and bioprocess engineering: Process Engineering in Biotechnology A. T. Jackson, 1990 |
| biotechnology and bioprocess engineering: Bioanalysis and Biosensors for Bioprocess Monitoring Bernhard Sonnleitner, 2014-01-15 The contributions to this special volume were selected in order to show present trends in the field of bioprocess monitoring and estimation. Established conventional methods are critically discussed and non-conventional ones introduced. Two papers focus on more fuzzy approaches such as electronic noses or advanced chemometric techniques. One contribution illustrates the high potential with the example of cephalosporin production. Three contributions dare to look inside the cells, one by the analysis of (microscopic) images, one by trying to estimate the so-called physiological state, and the third by analyzing the metabolic network. This shows how sophisticated (bio)chemical as well as mathematical analytical tools result in better understanding of living systems and bioprocesses. |
| biotechnology and bioprocess engineering: Bioreaction Engineering K. Schügerl, K.-H. Bellgardt, 2012-12-06 Alongside presenting the fundamentals, this book reviews the state of the art of mathematical modeling and control of bioprocesses, while demonstrating the application in various biological systems important to industry. At the same time, the application of different types of models and control strategies are illustrated, taking into account the recent developments in reactor modeling. In addition to modeling and control, the metabolic flux analysis and the metabolic design and their application to bioprocesses are considered. |
| biotechnology and bioprocess engineering: Bioprocessing Owen P. Ward, 2012-12-06 Methods for processing of biological materials into useful products represent essential core manufacturing activities of the food, chemical and pharmaceutical industries. On the one hand the techniques involved include well established process engineering methodologies such as mixing, heat transfer, size modification and a variety of separatIon and fermentation procedures. In addition, new bioprocessing practices arising from the exciting recent advances in biotech nology, including innovative fermentation cell culture and enzyme based operations, are rapidly extending the frontiers of bioprocessing. These develop ments are resulting in the introduction to the market place of an awesome range of novel biological products having unique applications. Indeed, the United States Office of Technology Assessment· has concluded that 'competitive advantage in areas related to biotechnology may depend as much on developments in bioprocess engineering as on innovations in genetics, immunology and other areas of basic science'. Advances in analytical instrumentation, computerization and process automation are playing an important role in process control and optimization and in the maintenance of product quality and consistency characteristics. Bioprocessing represents the industrial practice of biotechnology and is multidisciplinary in nature, integrating the biological, chemical and engineering sciences. This book discusses the individual unit operations involved and describes a wide variety of important industrial bioprocesses. I am very grateful to Sanjay Thakur who assisted me in the collection of material for this book. |
| biotechnology and bioprocess engineering: BIOCHEMICAL ENGINEERING MUKESH DOBLE, SATHYANARAYANA N. GUMMADI, 2007-01-21 This text is intended to provide students with a solid grounding in basic principles of biochemical engineering. Beginning with a historical review and essential concepts of biochemical engineering in part I, the next three parts are devoted to a comprehensive discussion of various topics in the areas of life sciences, kinetics of biological reactions and engineering principles. Having described the different building blocks of life, microbes, metabolism and bioenergetics, the book proceeds to explain enzymatic kinetics and kinetics of cell growth and product formation. The engineering principles cover transport phenomena in bioprocess systems and various bioreactors, downstream processing and environmental technology. Finally, the book concludes with an introduction to recombinant DNA technology. This textbook is designed for B.Tech. courses in biotechnology, B.Tech. courses in chemical engineering and other allied disciplines, and M.Sc. courses in biotechnology. |
| biotechnology and bioprocess engineering: Insect Cell Culture Engineering Mattheus F. A. Goosen, 2020-07-24 Consolidating and expanding current, fundamental notions of virology and animal cell cultivation, this practical reference examines the development of insect cell culture techniques for the production of recombinant proteins and insect pathogenic viruses.;Resolving on-the-job problems such as sparging cell damage and reduced infectivity cells, Insect Cell Culture Engineering: includes special introductory material as well as background information on insect pathogenic viruses, the molecular biology of baculoviruses and bioreactor design; offers advice on how to save time when deciding which insect cell line, bioreactor and medium to exploit; discusses the preparation of mathematical modelling in animal cell culture; addresses the concerns associated with insect cell immobilization and the use of serum-free culture media; provides insights into the protective effects of polymer additives and insect cell gene expression in pharmaceutical research; and analyzes process scale-up and reactor design.;Bridging the gap between laboratory research and pilot plant scale insect culture/baculovirus technology, Insect Cell Culture Engineering is designed as a reference for biochemical and bioprocess engineers, bioprocess technologists, biochemists, molecular and cell biologists, microbiologists, and upper-level undergraduate and graduate students in these disciplines. |
| biotechnology and bioprocess engineering: Fermentation and Biochemical Engineering Handbook Henry C. Vogel, Celeste M. Todaro, 1996-12-31 This is a well-rounded handbook of fermentation and biochemical engineering presenting techniques for the commercial production of chemicals and pharmaceuticals via fermentation. Emphasis is given to unit operations fermentation, separation, purification, and recovery. Principles, process design, and equipment are detailed. Environment aspects are covered. The practical aspects of development, design, and operation are stressed. Theory is included to provide the necessary insight for a particular operation. Problems addressed are the collection of pilot data, choice of scale-up parameters, selection of the right piece of equipment, pinpointing of likely trouble spots, and methods of troubleshooting. The text, written from a practical and operating viewpoint, will assist development, design, engineering and production personnel in the fermentation industry. Contributors were selected based on their industrial background and orientation. The book is illustrated with numerous figures, photographs and schematic diagrams. |
| biotechnology and bioprocess engineering: Fundamental Bioengineering John Villadsen, 2015-10-07 A thorough introduction to the basics of bioengineering, with a focus on applications in the emerging white biotechnology industry. As such, this latest volume in the Advanced Biotechnology series covers the principles for the design and analysis of industrial bioprocesses as well as the design of bioremediation systems, and several biomedical applications. No fewer than seven chapters introduce stoichiometry, kinetics, thermodynamics and the design of ideal and real bioreactors, illustrated by more than 50 practical examples. Further chapters deal with the tools that enable an understanding of the behavior of cell cultures and enzymatically catalyzed reactions, while others discuss the analysis of cultures at the level of the cell, as well as structural frameworks for the successful scale-up of bioreactions. In addition, a short survey of downstream processing options and the control of bioreactions is given. With contributions from leading experts in industry and academia, this is a comprehensive source of information peer-reviewed by experts in the field. |
| biotechnology and bioprocess engineering: Biochemical Engineering, Second Edition Douglas S. Clark, Harvey W. Blanch, 1997-02-14 This work provides comprehensive coverage of modern biochemical engineering, detailing the basic concepts underlying the behaviour of bioprocesses as well as advances in bioprocess and biochemical engineering science. It includes discussions of topics such as enzyme kinetics and biocatalysis, microbial growth and product formation, bioreactor design, transport in bioreactors, bioproduct recovery and bioprocess economics and design. A solutions manual is available to instructors only. |
| biotechnology and bioprocess engineering: Microbial Biotechnology Farshad Darvishi Harzevili, Hongzhang Chen, 2018-10-08 Incorporates the Experiences of World-Class Researchers Microbial Biotechnology: Progress and Trends offers a theoretical take on topics that relate to microbial biotechnology. The text uses the novel experimental experiences of various contributors from around the world—designed as case studies—to highlight relevant topics, issues, and recent developments surrounding this highly interdisciplinary field. It factors in metagenomics and microbial biofuels production, and incorporates major contributions from a wide range of disciplines that include microbiology, biochemistry, genetics, molecular biology, chemistry, biochemical engineering, and bioprocess engineering. In addition, it also provides a variety of photos, diagrams, and tables to help illustrate the material. The book consists of 15 chapters and contains subject matter that addresses: Microbial biotechnology from its historical roots to its different processes Some of the new developments in upstream processes Solid-state fermentation as an interesting field in modern fermentation processes Recent developments in the production of valuable microbial products such as biofuels, organic acids, amino acids, probiotics, healthcare products, and edible biomass Important microbial activities such as biofertilizer, biocontrol, biodegradation, and bioremediation Students, scientists, and researchers can benefit from Microbial Biotechnology: Progress and Trends, a resource that addresses biotechnology, applied microbiology, bioprocess/fermentation technology, healthcare/pharmaceutical products, food innovations/food processing, plant agriculture/crop improvement, energy and environment management, and all disciplines related to microbial biotechnology. |
| biotechnology and bioprocess engineering: Bioprocessing for Value-Added Products from Renewable Resources Shang-Tian Yang, 2011-08-11 Bioprocessing for Value-Added Products from Renewable Resources provides a timely review of new and unconventional techniques for manufacturing high-value products based on simple biological material. The book discusses the principles underpinning modern industrial biotechnology and describes a unique collection of novel bioprocesses for a sustainable future. This book begins in a very structured way. It first looks at the modern technologies that form the basis for creating a bio-based industry before describing the various organisms that are suitable for bioprocessing - from bacteria to algae - as well as their unique characteristics. This is followed by a discussion of novel, experimental bioprocesses, such as the production of medicinal chemicals, the production of chiral compounds and the design of biofuel cells. The book concludes with examples where biological, renewable resources become an important feedstock for large-scale industrial production. This book is suitable for researchers, practitioners, students, and consultants in the bioprocess and biotechnology fields, and for others who are interested in biotechnology, engineering, industrial microbiology and chemical engineering. ·Reviews the principles underpinning modern industrial biotechnology ·Provides a unique collection of novel bioprocesses for a sustainable future ·Gives examples of economical use of renewable resources as feedstocks ·Suitable for both non-experts and experts in the bioproduct industry |
| biotechnology and bioprocess engineering: Biosystems Engineering II Christiana Cordes, 2010-09-02 Biosystems Engineering I explores all aspects of biotechnology, which blends aspects of chemistry, biochemistry, microbiology, genetics, chemical engineering and computer sciences. Topics include the systems biology of industrial microorganisms, modeling languages for biochemical network simulation, and more. |
| biotechnology and bioprocess engineering: Computer and Information Science Applications in Bioprocess Engineering A.R. Moreira, Kimberlee K. Wallace, 2012-12-06 Biotechnology has been labelled as one of the key technologies of the last two decades of the 20th Century, offering boundless solutions to problems ranging from food and agricultural production to pharmaceutical and medical applications, as well as environmental and bioremediation problems. Biological processes, however, are complex and the prevailing mechanisms are either unknown or poorly understood. This means that adequate techniques for data acquisition and analysis, leading to appropriate modeling and simulation packages that can be superimposed on the engineering principles, need to be routine tools for future biotechnologists. The present volume presents a masterly summary of the most recent work in the field, covering: instrumentation systems; enzyme technology; environmental biotechnology; food applications; and metabolic engineering. |
| biotechnology and bioprocess engineering: Bioprocess Engineering Michael L. Shuler, Fikret Kargi, 2002 This concise yet comprehensive text introduces the essential concepts of bioprocessing - internal structure and functions of different types of microorganisms, major metabolic pathways, enzymes, microbial genetics, kinetics and stoichiometry of growth and product information - to traditional chemical engineers and those in related disciplines. It explores the engineering principles necessary for bioprocess synthesis and design, and illustrates the application of these principles to modern biotechnology for production of pharmaceuticals and biologics, solution of environmental problems, production of commodities, and medical applications. |
Home | Biotechnology and Bioprocess Engineering - Spri…
Features applied molecular and cell biology, engineered biocatalysis and biotransformation, metabolic engineering and systems biology, …
Volumes and issues | Biotechnology and Bioproces…
Biotechnology and Bioprocess Engineering is a bimonthly journal devoted to the advancement across wide areas of biotechnology, …
Aims and scope | Biotechnology and Bioproces…
Biotechnology and Bioprocess Engineering is an international bimonthly journal published by the Korean Society for Biotechnology …
Articles | Biotechnology and Bioprocess Engineering - Spri…
Jun 6, 2025 · Biotechnology and Bioprocess Engineering is a bimonthly journal devoted to the advancement across wide areas of biotechnology, …
Submission guidelines | Biotechnology and Bioproces…
To find out more about publishing your work Open Access in Biotechnology and Bioprocess Engineering, including information on fees, funding and …
Home | Biotechnology and Bioprocess Engineering - Springer
Features applied molecular and cell biology, engineered biocatalysis and biotransformation, metabolic engineering and systems biology, bioseparation and more. Welcomes research …
Volumes and issues | Biotechnology and Bioprocess Engineering
Biotechnology and Bioprocess Engineering is a bimonthly journal devoted to the advancement across wide areas of biotechnology, bioengineering and biomedical ...
Aims and scope | Biotechnology and Bioprocess Engineering
Biotechnology and Bioprocess Engineering is an international bimonthly journal published by the Korean Society for Biotechnology and Bioengineering. BBE is devoted to the advancement in …
Articles | Biotechnology and Bioprocess Engineering - Springer
Jun 6, 2025 · Biotechnology and Bioprocess Engineering is a bimonthly journal devoted to the advancement across wide areas of biotechnology, bioengineering and biomedical ...
Submission guidelines | Biotechnology and Bioprocess …
To find out more about publishing your work Open Access in Biotechnology and Bioprocess Engineering, including information on fees, funding and licences, visit our Open access …
Editorial | Biotechnology and Bioprocess Engineering - Springer
Jul 5, 2023 · Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Korea. Ki Jun Jeong. Department of Chemical …
How to publish with us | Biotechnology and Bioprocess Engineering
Subscription publishing model – published articles are made available to institutions and individuals who subscribe to Biotechnology and Bioprocess Engineering or who pay to read …
Recent Advances in Bioprocess Engineering and Bioreactor Design …
May 13, 2024 · Covers the recent advances in bioprocess engineering from research to applications; Introduces current techniques in bioprocess technology, bioreactor design, …
Photobioreactor engineering: Design and performance
Photobioreactor engineering for economical and effective utilization of algae and its products has made impressive and promising progress. Bioprocess engineers have expedited the design …
Volume 28, Issue 5 | Biotechnology and Bioprocess Engineering
Biotechnology and Bioprocess Engineering is a bimonthly journal devoted to the advancement across wide areas of biotechnology, bioengineering and biomedical ...
