| biomaterials science an introduction to materials in medicine: Biomaterials Science Buddy D. Ratner, Allan S. Hoffman, Frederick J. Schoen, Jack E. Lemons, 2012-12-31 The revised edition of this renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science. It provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine. - Over 29,000 copies sold, this is the most comprehensive coverage of principles and applications of all classes of biomaterials: the only such text that currently covers this area comprehensively - Materials Today - Edited by four of the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials - Fully revised and expanded, key new topics include of tissue engineering, drug delivery systems, and new clinical applications, with new teaching and learning material throughout, case studies and a downloadable image bank |
| biomaterials science an introduction to materials in medicine: Biomaterials Science Buddy D. Ratner, 2004-07-29 This second edition of Biomaterials Science leads the field by providing a balanced, insightful view of biomaterials. Contributions from pre-eminent researchers and practitioners from diverse academic and professional backgrounds have been integrated into a cohesive curriculum which includes pertinent principles of cell biology, immunology and pathology focusing on the clinical uses of biomaterials as components of implants, devices, and artificial organs, and their uses in biotechnology. The materials science and engineering of synthetic and natural biomaterials and the characterization of their physical, chemical, biochemical and surface properties, and mechanisms and evaluation of interactions with tissue, are also addressed in detail. Book jacket. |
| biomaterials science an introduction to materials in medicine: Biomaterials Science William R Wagner, Shelly E. Sakiyama-Elbert, Guigen Zhang, Michael J. Yaszemski, 2020-05-23 The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine.This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in the applications section, which includes the latest in topics such as nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Translation from the lab to commercial products is emphasized with new content dedicated to medical device development, global issues related to translation, and issues of quality assurance and reimbursement. In response to customer feedback, the new edition also features consolidation of redundant material to ensure clarity and focus. Biomaterials Science, 4th edition is an important update to the best-selling text, vital to the biomaterials' community. - The most comprehensive coverage of principles and applications of all classes of biomaterials - Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials - Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine and much more. - Online chapter exercises available for most chapters |
| biomaterials science an introduction to materials in medicine: Introductory Biomaterials Lia Stanciu, Susana Diaz-Amaya, 2021-09-23 Introductory Biomaterials enables undergraduate students in Biomedical, Chemical, Materials and other relevant Engineering disciplines to become familiar with the key concepts of Biomaterials principles: biocompatibility, structure-property-applications relationships, mechanical response of natural tissues, and cellular pathways for tissue-material ingrowth. Written in a clear, concise manner that weds theory with applications, this book helps students to understand the often intricate relationships between materials the implant devices that are made from them, and how the human body reacts to them. The book includes such concepts as requirements for metals, alloys, and ceramic materials to be used in load bearing implants (corrosion concepts, stress shielding, mechanical properties, composition), what properties of polymers impact their use in medicine (leaching and swelling, creep and stress relaxation); the tissue response to biomaterials, concepts related to drug delivery applications (polymer degradation, encapsulation), and tissue engineering (scaffold porosity, diffusion of nutrients, mechanical properties). - Begins with structure-properties, followed immediately by their impact on actual biomaterials classes and devices, thus directly relating theory to applications (e.g. polymers to polymeric stents; metals to fracture fixation devices) - Explains concepts in a clear, progressive manner, with numerous examples and figures to enhance student learning - Covers all key biomaterials classes: metallic, ceramic, polymeric, composite and biological - Includes a timely chapter on medical device regulation |
| biomaterials science an introduction to materials in medicine: Introduction to Biomaterials J. L. Ong, Mark R. Appleford, Gopinath Mani, 2014 A succinct introduction to the field of biomaterials engineering, packed with practical insights. |
| biomaterials science an introduction to materials in medicine: 生物材料科学/医用材料导论/[英文本]/Biomaterials science Buddy D. Ratner, 2004 国外大学优秀教材——材料科学与工程系列 |
| biomaterials science an introduction to materials in medicine: Biomaterials in Translational Medicine Lei Yang, Sarit Bhaduri, Thomas J. Webster, 2018-11-30 Biomaterials in Translational Medicine delivers timely and detailed information on the latest advances in biomaterials and their role and impact in translational medicine. Key topics addressed include the properties and functions of these materials and how they might be applied for clinical diagnosis and treatment. Particular emphasis is placed on basic fundamentals, biomaterial formulations, design principles, fabrication techniques and transitioning bench-to-bed clinical applications. The book is an essential reference resource for researchers, clinicians, materials scientists, engineers and anyone involved in the future development of innovative biomaterials that drive advancement in translational medicine. - Systematically introduces the fundamental principles, rationales and methodologies of creating or improving biomaterials in the context of translational medicine - Includes the translational or commercialization status of these new biomaterials - Provides the reader with enough background knowledge for a fundamental grip of the difficulties and technicalities of using biomaterial translational medicine - Directs the reader on how to find other up-to-date sources (i.e. peer reviewed journals) in the field of translational medicine and biomaterials |
| biomaterials science an introduction to materials in medicine: Integrated Biomaterials Science Rolando Barbucci, 2002-10-31 Integrated Biomaterials Science provides an intriguing insight into the world of biomaterials. It explores the materials and technology which have brought advances in new biomaterials, highlighting the way in which modern biology and medicine are synergistically linked to other key scientific disciplines-physics, chemistry, and engineering. In doing so, Integrated Biomaterials Science contains chapters on tissue engineering and gene therapy, standards and parameters of biomaterials, applications and interactions within the industrial world, as well as potential aspects of patent regulations. Integrated Biomaterials Science serves as a comprehensive guide to understanding this dynamic field, yet is designed so that chapters may be read and understood independently, depending on the needs of the reader. Integrated Biomaterials Science is attractive to a broad audience interested in a deeper understanding of this evolving field, and serves as a key resource for researchers and students of biomaterials courses, providing all with an opportunity to probe further. Key Features: -Comprehensively covers the latest developments in the field, -Each chapter is written by key field leaders, -Covers applications and interactions within the industrial world, -Presents standards on biomaterials, -Explores aspects of patent regulations and patentability of biomaterials, -Exceptionally detailed, yet easily understood - perfect as a guide for professional researchers or as a text for emerging students. |
| biomaterials science an introduction to materials in medicine: An Introduction To Biomaterials Science And Engineering A Sandeep Kranthi Kiran, Seeram Ramakrishna, 2021-04-22 This book presents a broad scope of the field of biomaterials science and technology, focusing on theory, advances and applications. It is written for those who would like to develop their interest and knowledge towards biomaterials or materials science and engineering. All aspects of biomaterials science are thoroughly addressed, from basic principles of biomaterials, organs and medical devices to advanced topics such as tissue engineering, surface engineering, sterilization techniques, 3D printing and drug delivery systems. Readers are also introduced to major concepts of surface modification techniques, and potential applications of different classes of biomaterials. Multiple-choice questions at the end of every chapter will be helpful for students to test their understanding of each topic, with answers provided at the end of the book.Ultimately, this book offers a one-stop source of information on the essentials of biomaterials and engineering. It is useful both as an introduction and advanced reference on recent advances in the biomaterials field. Suitable readers include undergraduate and graduate students, especially those in Materials Science, Biomedical Engineering and Bioengineering. |
| biomaterials science an introduction to materials in medicine: An Introduction to Tissue-Biomaterial Interactions Kay C. Dee, David A. Puleo, Rena Bizios, 2003-04-14 An Introduction to Tissue-Biomaterial Interactions acquaints an undergraduate audience with the fundamental biological processes that influence these sophisticated, cutting-edge procedures. Chapters one through three provide more detail about the molecular-level events that happen at the tissue-implant interface, while chapters four through ten explore selected material, biological, and physiological consequences of these events. The importance of the body’s wound-healing response is emphasized throughout. Specific topics covered include:Structure and properties of biomaterials Proteins Protein-surface interactions Blood-biomaterial interactions Inflammation and infection The immune system Biomaterial responses to implantation Biomaterial surface engineering Intimal hyperplasia and osseointegration as examples of tissue-biomaterial interactions The text also provides extensive coverage of the three pertinent interfaces between the body and the biomaterial, between the body and the living cells, and between the cells and the biomaterial that are critical in the development of tissue-engineered products that incorporate living cells within a biomaterial matrix. Ideal for a one-semester, biomedical engineering course, An Introduction to Tissue-Biomaterial Interactions provides a solid framework for understanding today’s and tomorrow’s implantable biomedical devices. |
| biomaterials science an introduction to materials in medicine: An Introduction to Biomaterials Jeffrey O. Hollinger, 2005-12-21 The complexity of biological systems and the need to design and develop biomedical therapies poses major challenges to professionals in the biomedical disciplines. An Introduction to Biomaterials emphasizes applications of biomaterials for patient care. Containing chapters prepared by leading authorities on key biomaterial types, this book underscores the process of biomaterial design, development directed toward clinical application, and testing that leads to therapies for clinical targets. The authors provide a lucid perspective on the standards available and the logic behind the standards in which biomaterials address clinical needs. This volume includes chapters on consensus standards and regulatory approaches to testing paradigms, followed by an analysis of specific classes of biomaterials. The book closes with sections on clinical topics that integrate materials sciences and patient applications. |
| biomaterials science an introduction to materials in medicine: Biomaterials Rosario Pignatello, 2011-11-14 These contribution books collect reviews and original articles from eminent experts working in the interdisciplinary arena of biomaterial development and use. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different synthetic and engineered biomaterials. Contributions were selected not based on a direct market or clinical interest, but based on results coming from very fundamental studies. This too will allow to gain a more general view of what and how the various biomaterials can do and work for, along with the methodologies necessary to design, develop and characterize them, without the restrictions necessarily imposed by industrial or profit concerns. The chapters have been arranged to give readers an organized view of this research area. In particular, this book contains 25 chapters related to recent researches on new and known materials, with a particular attention to their physical, mechanical and chemical characterization, along with biocompatibility and hystopathological studies. Readers will be guided inside the range of disciplines and design methodologies used to develope biomaterials possessing the physical and biological properties needed for specific medical and clinical applications. |
| biomaterials science an introduction to materials in medicine: Biomaterials Qizhi Chen, George Thouas, 2014-12-15 Explores Biomedical Science from a Unique PerspectiveBiomaterials: A Basic Introduction is a definitive resource for students entering biomedical or bioengineering disciplines. This text offers a detailed exploration of engineering and materials science, and examines the boundary and relationship between the two. Based on the author's course lectur |
| biomaterials science an introduction to materials in medicine: Structural Biomaterials Cuie Wen, 2021-04-06 Structural Biomaterials: Properties, Characteristics, and Selection serves as a single point of reference to digest current research and develop a deeper understanding in the field of biomaterials engineering. This book uses a materials-focused approach, allowing the reader to quickly access specific, detailed information on biomaterials characterization and selection. Relevant to a range of readers, this book provides holistic coverage of the broad categories of structural biomaterials currently available and used in medical applications, highlighting the property requirements for structural biomaterials, their biocompatibility performance and their safety regulation in key categories such as metals, ceramics and polymers. The materials science perspective of this text ensures the content is accessible even to those without an extensive background in applied medicine, positioning this text not just for students, but as an overview and reference for researchers, scientists and engineers entering the field from related materials science disciplines. - Provides a unique, holistic approach, covering key biomaterials categories in one text, including metals, ceramics and polymers - Discusses advantages, disadvantages, biocompatibility performance and safety regulations, allowing for accurate materials selection in medical applications - Utilizes a materials science perspective, allowing those without an extensive applied medical background to learn about the field |
| biomaterials science an introduction to materials in medicine: Definitions of Biomaterials for the Twenty-First Century Xingdong Zhang, David Williams, 2019-06-20 Definitions of Biomaterials for the Twenty-First Century is a review of key, critical biomaterial terms and definitions endorsed by the International Union of Societies for Biomaterials Science and Engineering. The topics and definitions discussed include those in general biomaterials and applications, biocompatibility, implantable and interventional devices, drug delivery systems, regenerative medicine and emerging biomaterials. The book reviews the discussion of these terms by leaders in the global biomaterials community and summarizes the agreed upon definitions. - Provides readers with the official definitions of critical biomaterials terms endorsed by the International Union of Societies for Biomaterials Science and Engineering - Includes the combined contributions from more than 50 global leaders in the biomaterials community - Updates terms based on the latest advances in clinical and scientific understanding and expanded scope of biomaterials science |
| biomaterials science an introduction to materials in medicine: Materials in Biology and Medicine Sunggyu Lee, David Henthorn, 2012-03-21 While the interdisciplinary field of materials science and engineering is relatively new, remarkable developments in materials have emerged for biological and medical applications, from biocompatible polymers in medical devices to the use of carbon nanotubes as drug delivery vehicles. With peer-reviewed chapters written by a select group of academic and industry experts, this comprehensive yet accessible book covers the most advanced materials used in biology and medicine. The book focuses on biomaterials and bioinspired materials, functional and responsive materials, controlling biology with materials, and the development of devices and enabling technologies. It will help readers tackle challenges of novel materials, carry out new process and product development projects, and create new methodologies for applications that enhance the quality of life. |
| biomaterials science an introduction to materials in medicine: Biomaterials Science and Tissue Engineering Bikramjit Basu, 2017-09-15 Covers key principles and methodologies of biomaterials science and tissue engineering with the help of numerous case studies. |
| biomaterials science an introduction to materials in medicine: Biomaterials Science and Biocompatibility Frederick H. Silver, David L. Christiansen, 2012-12-06 Adopting an interdisciplinary approach to the chemistry and physics of materials, their biocompatibility, and the consequences of implantation of such devices into the human body, this text introduces readers to the principles of polymer science and the study of metals, ceramics and composites, and also to the basic biology required to understand the nature of the host-transplant interface. Topics covered include the macromolecular components of cells and tissues, self-assembly processes, biological cascade systems, microscopic structure of cells and tissues, immunology, transplantation biology, and the pathobiology of wound healing. The materials science section includes the structures and properties of polymers, metals, ceramics and composites, and the processes for forming materials as well as the pathobiology of devices. The final two chapters deal with tissue engineering and the relations between the biology of cells and tissue transplantation, and the engineering of tissue replacements using passaged cells. |
| biomaterials science an introduction to materials in medicine: Essential Biomaterials Science David Williams, 2014-07-17 This groundbreaking single-authored textbook equips students with everything they need to know to truly understand the hugely topical field of biomaterials science, including essential background on the clinical necessity of biomaterials, relevant concepts in biology and materials science, comprehensive and up-to-date coverage of all existing clinical and experimental biomaterials, and the fundamental principles of biocompatibility. It features extensive case studies interweaved with theory, from a wide range of clinical disciplines, equipping students with a practical understanding of the phenomena and mechanisms of biomaterials performance; a whole chapter dedicated to the biomaterials industry itself, including guidance on regulations, standards and guidelines, litigation, and ethical issues to prepare students for industry; informative glossaries of key terms, engaging end-of-chapter exercises, and up-to-date lists of recommended reading. Drawing on the author's 40 years' experience in biomaterials, this is an indispensible resource for students studying these lifesaving technological advances. |
| biomaterials science an introduction to materials in medicine: Materials for Medical Application Robert B. Heimann, 2020-08-24 This book gives an introduction to the highly interdisciplinary field of biomaterials. It concisely summarizes properties, synthesis and modification of materials such as metals, ceramics, polymers or composites. Characterization, in vitro and in vivo testing as well as a selection of various applications are also part of this inevitable guide. |
| biomaterials science an introduction to materials in medicine: Materials for Biomedical Engineering Mohamed N. Rahaman, Roger F. Brown, 2021-11-23 MATERIALS FOR BIOMEDICAL ENGINEERING A comprehensive yet accessible introductory textbook designed for one-semester courses in biomaterials Biomaterials are used throughout the biomedical industry in a range of applications, from cardiovascular devices and medical and dental implants to regenerative medicine, tissue engineering, drug delivery, and cancer treatment. Materials for Biomedical Engineering: Fundamentals and Applications provides an up-to-date introduction to biomaterials, their interaction with cells and tissues, and their use in both conventional and emerging areas of biomedicine. Requiring no previous background in the subject, this student-friendly textbook covers the basic concepts and principles of materials science, the classes of materials used as biomaterials, the degradation of biomaterials in the biological environment, biocompatibility phenomena, and the major applications of biomaterials in medicine and dentistry. Throughout the text, easy-to-digest chapters address key topics such as the atomic structure, bonding, and properties of biomaterials, natural and synthetic polymers, immune responses to biomaterials, implant-associated infections, biomaterials in hard and soft tissue repair, tissue engineering and drug delivery, and more. Offers accessible chapters with clear explanatory text, tables and figures, and high-quality illustrations Describes how the fundamentals of biomaterials are applied in a variety of biomedical applications Features a thorough overview of the history, properties, and applications of biomaterials Includes numerous homework, review, and examination problems, full references, and further reading suggestions Materials for Biomedical Engineering: Fundamentals and Applications is an excellent textbook for advanced undergraduate and graduate students in biomedical materials science courses, and a valuable resource for medical and dental students as well as students with science and engineering backgrounds with interest in biomaterials. |
| biomaterials science an introduction to materials in medicine: Joining and Assembly of Medical Materials and Devices Y N Zhou, M D Breyen, 2013-05-31 As medical devices become more intricate, with an increasing number of components made from a wide range of materials, it is important that they meet stringent requirements to ensure that they are safe to be implanted and will not be rejected by the human body. Joining and assembly of medical materials and devices provides a comprehensive overview of joining techniques for a range of medical materials and applications.Part one provides an introduction to medical devices and joining methods with further specific chapters on microwelding methods in medical components and the effects of sterilization on medical materials and welded devices. Part two focuses on medical metals and includes chapters on the joining of shape memory alloys, platinum (Pt) alloys and stainless steel wires for implantable medical devices and evaluating the corrosion performance of metal medical device welds. Part three moves on to highlight the joining and assembly of medical plastics and discusses techniques including ultrasonic welding, transmission laser welding and radio frequency (RF)/dielectric welding. Finally, part four discusses the joining and assembly of biomaterial and tissue implants including metal-ceramic joining techniques for orthopaedic applications and tissue adhesives and sealants for surgical applications.Joining and assembly of medical materials and devices is a technical guide for engineers and researchers within the medical industry, professionals requiring an understanding of joining and assembly techniques in a medical setting, and academics interested in this field. - Introduces joining methods in medical applications including microwelding and considers the effects of sterilization on the resulting joints and devices - Considers the joining, assembly and corrosion performance of medical metals including shape memory alloys, platinum alloys and stainless steel wires - Considers the joining and assembly of medical plastics including multiple welding methods, bonding strategies and adhesives |
| biomaterials science an introduction to materials in medicine: Metallic Biomaterials Processing and Medical Device Manufacturing Cuie Wen, 2020-08-20 Metallic Biomaterials Processing and Medical Device Manufacturing details the principles and practices of the technologies used in biomaterials processing and medical device manufacturing. The book reviews the main categories of metallic biomaterials and the essential considerations in design and manufacturing of medical devices. It bridges the gap between the designing of biomaterials and manufacturing of medical devices including requirements and standards. Main themes of the book include, manufacturing, coatings and surface modifications of medical devices, metallic biomaterials and their mechanical behaviour, degradation, testing and characterization, and quality controls, standards and FDA regulations of medical devices. The leading experts in the filed discuss the requirements, challenges, recent progresses and future research directions in the processing of materials and manufacturing of medical devices. Metallic Biomaterials Processing and Medical Device Manufacturing is ideal for those working in the disciplines of materials science, manufacturing, biomedical engineering, and mechanical engineering. - Reviews key topics of biomaterials processing for medical device applications including metallic biomaterials and their mechanical behavior, degradation, testing and characterization - Bridges the gap between biomaterials design and medical device manufacturing - Discusses the quality controls, standards, and FDA requirements for biomaterials and medical devices |
| biomaterials science an introduction to materials in medicine: Biomedical Materials Roger Narayan, 2009-06-20 Biomedical Materials provides a comprehensive discussion of contemporary biomaterials research and development. Highlighting important topics associated with Engineering, Medicine and Surgery, this volume reaches a wide scope of professionals, researchers and graduate students involved with biomaterials. A pedagogical writing style and structure provides readers with an understanding of the fundamental concepts necessary to pursue research and industrial work on biomaterials, including characteristics of biomaterials, biological processes, biocompatibility, and applications of biomaterials in implants and medical instruments. Written by leading researchers in the field, this text book takes readers to the forefront of biomedical materials development, providing them with a taste of how the field is changing, while also serving as a useful reference to physicians and engineers. |
| biomaterials science an introduction to materials in medicine: Introduction to Biomaterials Donglu Shi, 2006 This book gives a fundmaentally comprehensive introduction to most of the important biomaterials including ceramics, metals, and polymers. |
| biomaterials science an introduction to materials in medicine: Nanostructured Biomaterials for Regenerative Medicine Vincenzo Guarino, Michele Iafisco, Silvia Spriano, 2019-10-05 Nanostructured Biomaterials for Regenerative Medicine focuses on the definition of new trends for the design of biomaterials for biomedical applications. It includes the ex novo synthesis as well as technological strategies to manipulate them into appropriate two-dimensional (2D) and three-dimensional (3D) forms, in order to impart all the main physical, chemical, structural and biological properties requested to achieve desired clinical efficacy. This book aims at offering a concise overview of innovative platforms based on nanostructured biomaterials as a function of their chemical nature - established by a consolidated material classification i.e., polymer, ceramics and metals. For each class, emerging bioinspired systems with rapid expansion in the biomedical research area and fabricated via new enabling technologies will be proposed for the use in tissue repair/regeneration and nanomedicine. This book is an essential resource for researchers, academics and professionals interested in the potential of nanostructured biomaterials for regenerative medicine. - Classifies materials into three classes for comprehensive discussion - Discusses design techniques to create innovative nanostructured biomaterials - Looks at enabling technologies and strategies for emerging applications |
| biomaterials science an introduction to materials in medicine: Biomedical Nanostructures Kenneth Gonsalves, Craig Halberstadt, Cato T. Laurencin, Lakshmi Nair, 2007-11-09 Learn to Use Nanoscale Materials to Design Novel Biomedical Devices and Applications Discover how to take full advantage of nanoscale materials in the design and fabrication of leading-edge biomedical devices. The authors introduce you to a variety of possible clinical applications such as drug delivery, diagnostics, and cancer therapy. In addition, the authors explore the interface between micron and nanoscale materials for the development of applications such as tissue engineering. Finally, they examine the mechanisms of cell interactions with material surfaces through the use of nanotechnology-based material processing and characterization methods. The text's three sections highlight its interdisciplinary approach: * Part One: Nanostructure Fabrication * Part Two: Bio-Nano Interfaces * Part Three: Clinical Applications of Nanostructures Among the key topics covered are nanotechnology in tissue regeneration; biomolecular engineering; receptor-ligand interactions; cell-biomaterial interactions; nanomaterials in diagnostics, drug delivery, and cancer therapy; and nano- and micron-level engineering and fabrication. Throughout the text, clear examples guide you through the chemistry and the processing involved in designing and developing nanoscale materials for biomedical devices. Each chapter begins with an introduction and ends with a conclusion highlighting the key points. In addition, references at the end of the chapter help you expand your research on any individual topic. In summary, this book helps biomedical researchers and engineers understand the physical phenomena that occur at the nanoscale in order to design novel cell-based constructs for a wide range of applications. |
| biomaterials science an introduction to materials in medicine: Biomaterials, Artificial Organs and Tissue Engineering L Hench, J. Jones, 2005-09-27 Maintaining quality of life in an ageing population is one of the great challenges of the 21st Century. This book summarises how this challenge is being met by multi-disciplinary developments of specialty biomaterials, devices, artificial organs and in-vitro growth of human cells as tissue engineered constructs.Biomaterials, Artificial Organs and Tissue Engineering is intended for use as a textbook in a one semester course for upper level BS, MS and Meng students. The 25 chapters are organized in five parts: Part one provides an introduction to living and man-made materials for the non-specialist; Part two is an overview of clinical applications of various biomaterials and devices; Part three summarises the bioengineering principles, materials and designs used in artificial organs; Part four presents the concepts, cell techniques, scaffold materials and applications of tissue engineering; Part five provides an overview of the complex socio-economic factors involved in technology based healthcare, including regulatory controls, technology transfer processes and ethical issues. - Comprehensive introduction to living and man-made materials - Looks at clinical applications of various biomaterials and devices - Bioengineering principles, materials and designs used in artificial organs are summarised |
| biomaterials science an introduction to materials in medicine: Biomaterials and Engineering for Implantology Yoshiki Oshida, Takashi Miyazaki, 2022-02-07 Biomaterials are composed of metallic materials, ceramics, polymers, composites and hybrid materials. Biomaterials used in human beings require safety regulations, toxicity, allergic reaction, etc. When used as implantable materials their biological compatibility, biomechanical compatibility, and morphological compatibility must be acessed. This book explores the design and requirements of biomaterials for the use in implantology. |
| biomaterials science an introduction to materials in medicine: Biomaterials for Clinical Applications Sujata K. Bhatia, 2010-10-14 Biomaterials for Clinical Applications is organized according to the World Health Organization’s report of the top 11 causes of death worldwide, and lays out opportunities for both biomaterials scientists and physicians to tackle each of these leading contributors to mortality. The introductory chapter discusses the global burden of disease. Each of the subsequent eleven chapters focuses on a specific disease process, beginning with the leading cause of death worldwide, cardiovascular disease. The chapters start with describing diseases where clinical needs are most pressing, and then envisions how biomaterials can be designed to address these needs, instead of the more technologically centered approached favored by most books in the field. This book, then, should appeal to chemical engineers and bioengineers who are designing new biomaterials for drug delivery and vaccine delivery, as well as tissue engineering. |
| biomaterials science an introduction to materials in medicine: Advances in Calcium Phosphate Biomaterials Besim Ben-Nissan, 2014-04-17 Advances in Calcium Phosphate Biomaterials presents a comprehensive, state-of-the-art review of the latest advances in developing calcium phosphate biomaterials and their applications in medicine. It covers the fundamental structures, synthesis methods, characterization methods, and the physical and chemical properties of calcium phosphate biomaterials, as well as the synthesis and properties of calcium phosphate-based biomaterials in regenerative medicine and their clinical applications. The book brings together these new concepts, mechanisms and methods in contributions by both young and “veteran” academics, clinicians, and researchers to forward the knowledge and expertise on calcium phosphate and related materials. Accordingly, the book not only covers the fundamentals but also open new avenues for meeting future challenges in research and clinical applications. Besim Ben-Nissan is a Professor of Chemistry and Forensic Science at the University of Technology, Sydney, Australia |
| biomaterials science an introduction to materials in medicine: Handbook Of Biomaterials Evaluation Andreas F von Recum, 1998-12-18 This handbook addresses the needs of those who are involved in inventing, developing, and testing implants and are concerned about the interactions between biomaterial and body tissue. The authors explore the physical, chemical, mechanical and regulatory considerations of synthetic materials used in surgical and implant procedures, and how these factors impact the latest developments and new approaches. This updated edition provides the biomaterials professional with necessary information on a range of issues, including bulk characterization, surface evaluations, toxicological evaluations, in vitro methods for safety evaluation, methods for evaluating materials in special applications, surgical considerations, systems implantology, soft and hard tissue history, regulatory aspects, and clinical trials. |
| biomaterials science an introduction to materials in medicine: Handbook of Biomaterials Biocompatibility Masoud Mozafari, 2020-06-16 Handbook of Biomaterials Biocompatibility is a systematic reference on host response to different biomaterials, taking into account their physical, mechanical and chemical properties. The book reviews recent progress in the design and study of biomaterials biocompatibility, along with current understanding on how to control immune system response. Sections provide the fundamental theories and challenges of biomaterials biocompatibility, the role of different biomaterials physicochemical surface properties on cell responses, cell responses to different physicochemical properties of polymers, ceramics, metals, carbons and nanomaterials, and biomaterials in different tissues, such as the cardiac, nervous system, cartilage and bone. This resource will be suitable for those working in the fields of materials science, regenerative engineering, medicine, medical devices and nanotechnology. |
| biomaterials science an introduction to materials in medicine: Stem Cells and Biomaterials for Regenerative Medicine Marek J. Los, Andrzej Hudecki, Emilia Wiechec, 2018-11-07 Stem Cells and Biomaterials for Regenerative Medicine addresses the urgent need for a compact source of information on both the cellular and biomaterial aspects of regenerative medicine. By developing a mutual understanding between three separately functioning areas of science—medicine, the latest technology, and clinical economics—the volume encourages interdisciplinary relationships that will lead to solutions for the significant challenges faced by today's regenerative medicine. Users will find sections on the homeostatic balance created by apoptosis and proliferating tissue stem cells, the naturally regenerative capacities of various tissue types, the potential regenerative benefits of iPS-generation, various differentiation protocols, and more. Written in easily accessbile language, this volume is appropriate for any professional or medical staff looking to expand their knowledge with regard to stem cells and regenerative medicine. - Arms readers with key information on tissue engineering, artificial organs and biomaterials, while using broadly accessible language - Provides broad introduction to, and examples of, various types of stem cells, core concepts of regenerative medicine, biomaterials, nanotechnology and nanomaterials, somatic cell transdyferentiation, and more - Edited and authored by researchers with expertise in regenerative medicine, (cancer) stem cells, biomaterials, genetics and nanomaterials |
| biomaterials science an introduction to materials in medicine: Engineering Materials for Biomedical Applications Swee Hin Teoh, 2004 The success of any implant or medical device depends very much on the biomaterial used. Synthetic materials (such as metals, polymers and composites) have made significant contributions to many established medical devices. The aim of this book is to provide a basic understanding on the engineering and processing aspects of biomaterials used in medical applications. Of paramount importance is the tripartite relationship between material properties, processing methods and design. As the target audiences cover a wide interdisciplinary field, each chapter is written with a detailed background so that audience of another discipline will be able to understand. For the more knowledgeable reader, a detailed list of references is included. |
| biomaterials science an introduction to materials in medicine: Biomaterials and Regenerative Medicine in Ophthalmology Traian Chirila, Damien Harkin, 2009-12-18 With an increasingly aged population, eye diseases are becoming more widespread. Biomaterials have contributed in recent years to numerous medical devices for the restoration of eyesight, improving many patients' quality of life. Consequently, biomaterials and regenerative medicine are becoming increasingly important to the advances of ophthalmology and optometry. Biomaterials and regenerative medicine in ophthalmology reviews the present status and future direction of biomaterials and regenerative medicine in this important field.Part one discusses applications in the anterior segment of the eye with chapters on such topics as advances in intraocular lenses (IOLs), synthetic corneal implants, contact lenses, and tissue engineering of the lens. Part two then reviews applications in the posterior segment of the eye with such chapters on designing hydrogels as vitreous substitutes, retinal repair and regeneration and the development of tissue engineered membranes. Chapters in Part three discuss other pertinent topics such as hydrogel sealants for wound repair in ophthalmic surgery, orbital enucleation implants and polymeric materials for orbital reconstruction.With its distinguished editor and international team of contributors, Biomaterials and regenerative medicine in ophthalmology is a standard reference for scientists and clinicians, as well as all those concerned with this ophthalmology. - Reviews the increasingly important role of biomaterials and regenerative medicine in the advancement of ophthalmology and optometry - Provides an overview of the present status and future direction of biomaterials and regenerative medicine in this important field - Discusses applications in both the anterior and prosterior segments of the eye with chapters on such topics as synthetic corneal implants and retinal repair and regeneration |
| biomaterials science an introduction to materials in medicine: Biomimetic Medical Materials Insup Noh, 2018-11-23 This volume outlines the current status in the field of biomimetic medical materials and illustrates research into their applications in tissue engineering. The book is divided into six parts, focusing on nano biomaterials, stem cells, tissue engineering, 3D printing, immune responses and intellectual property. Each chapter has its own introduction and outlines current research trends in a variety of applications of biomimetic medical materials. The biomimetic medical materials that are covered include functional hydrogels, nanoparticles for drug delivery and medicine, the 3D bioprinting of biomaterials, sensor materials, stem cell interactions with biomaterials, immune responses to biomaterials, biodegradable hard scaffolds for tissue engineering, as well as other important topics, like intellectual property. Each chapter is written by a team of experts. This volume attempts to introduce the biomimetic properties of biomedical materials within the context of our current understanding of the nanotechnology of nanoparticles and fibres and the macroscopic aspects of 3D bioprinting. |
| biomaterials science an introduction to materials in medicine: Titanium in Medicine D.M. Brunette, P. Tengvall, Marcus Textor, P. Thomsen, 2012-12-06 Providing scientific and technical in-depth information in a clear format with a homogeneous structure, this text is suited for educational and self-teaching purposes as well as a reference on titanium for biomedical applications. It covers the whole area relevant to the use of titanium for implants, devices and instruments in medicine: material and surface science, physics, chemistry, biology, medicine, quality and regulatory aspects. |
| biomaterials science an introduction to materials in medicine: Biomaterials in Clinical Practice Fatima Zivic, Saverio Affatato, Miroslav Trajanovic, Matthias Schnabelrauch, Nenad Grujovic, Kwang Leong Choy, 2017-10-20 This book covers the properties of biomaterials that have found wide clinical applications, while also reviewing the state-of-the-art in the development towards future medical applications, starting with a brief introduction to the history of biomaterials used in hip arthroplasty. The book then reviews general types of biomaterials – polymers, ceramics, and metals, as well as different material structures such as porous materials and coatings and their applications – before exploring various current research trends, such as biodegradable and porous metals, shape memory alloys, bioactive biomaterials and coatings, and nanometals used in the diagnosis and therapy of cancer. In turn, the book discusses a range of methods and approaches used in connection with biomaterial properties and characterization – chemical properties, biocompatibility, in vivo behaviour characterisation, as well as genotoxicity and mutagenicity – and reviews various diagnostic techniques: histopathological analysis, imagining techniques, and methods for physicochemical and spectroscopic characterization. Properties of stent deployment procedures in cardiovascular surgeries, from aspects of prediction, development and deployment of stent geometries are presented on the basis of novel modelling approaches. The last part of the book presents the clinical applications of biomaterials, together with case studies in dentistry, knee and hip prosthesis. Reflecting the efforts of a multidisciplinary team of authors, gathering chemical engineers, medical doctors, physicists and engineers, it presents a rich blend of perspectives on the application of biomaterials in clinical practice. The book will provide clinicians with an essential review of currently available solutions in specific medical areas, also incorporating non-medical solutions and standpoints, thus offering them a broader selection of materials and implantable solutions. This work is the result of joint efforts of various academic and research institutions participating in WIMB Tempus project, 543898-TEMPUS-1-2013-1-ES-TEMPUS-JPHES, Development of Sustainable Interrelations between Education, Research and Innovation at WBC Universities in Nanotechnologies and Advanced Materials where Innovation Means Business, co-funded by the Tempus Programme of the European Union. |
| biomaterials science an introduction to materials in medicine: Biosurfaces Kantesh Balani, Vivek Verma, Arvind Agarwal, Roger Narayan, 2015-01-23 Ideal as a graduate textbook, this title is aimed at helping design effective biomaterials, taking into account the complex interactions that occur at the interface when a synthetic material is inserted into a living system. Surface reactivity, biochemistry, substrates, cleaning, preparation, and coatings are presented, with numerous case studies and applications throughout. Highlights include: Starts with concepts and works up to real-life applications such as implantable devices, medical devices, prosthetics, and drug delivery technology Addresses surface reactivity, requirements for surface coating, cleaning and preparation techniques, and characterization Discusses the biological response to coatings Addresses biomaterial-tissue interaction Incorporates nanomechanical properties and processing strategies |
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