| bioprocess and biosystems engineering: Bioprocess Engineering Shijie Liu, 2012-11-21 Bioprocess Engineering involves the design and development of equipment and processes for the manufacturing of products such as food, feed, pharmaceuticals, nutraceuticals, chemicals, and polymers and paper from biological materials. It also deals with studying various biotechnological processes. Bioprocess Kinetics and Systems Engineering first of its kind contains systematic and comprehensive content on bioprocess kinetics, bioprocess systems, sustainability and reaction engineering. Dr. Shijie Liu reviews the relevant fundamentals of chemical kinetics-including batch and continuous reactors, biochemistry, microbiology, molecular biology, reaction engineering, and bioprocess systems engineering- introducing key principles that enable bioprocess engineers to engage in the analysis, optimization, design and consistent control over biological and chemical transformations. The quantitative treatment of bioprocesses is the central theme of this book, while more advanced techniques and applications are covered with some depth. Many theoretical derivations and simplifications are used to demonstrate how empirical kinetic models are applicable to complicated bioprocess systems. - Contains extensive illustrative drawings which make the understanding of the subject easy - Contains worked examples of the various process parameters, their significance and their specific practical use - Provides the theory of bioprocess kinetics from simple concepts to complex metabolic pathways - Incorporates sustainability concepts into the various bioprocesses |
| bioprocess and biosystems engineering: Biosystems Engineering II Christiana Cordes, 2010-09-02 Biosystems Engineering I explores all aspects of biotechnology, which blends aspects of chemistry, biochemistry, microbiology, genetics, chemical engineering and computer sciences. Topics include the systems biology of industrial microorganisms, modeling languages for biochemical network simulation, and more. |
| bioprocess and biosystems engineering: Bioprocess Engineering Principles Pauline M. Doran, 1995-04-03 The emergence and refinement of techniques in molecular biology has changed our perceptions of medicine, agriculture and environmental management. Scientific breakthroughs in gene expression, protein engineering and cell fusion are being translated by a strengthening biotechnology industry into revolutionary new products and services. Many a student has been enticed by the promise of biotechnology and the excitement of being near the cutting edge of scientific advancement. However, graduates trained in molecular biology and cell manipulation soon realise that these techniques are only part of the picture. Reaping the full benefits of biotechnology requires manufacturing capability involving the large-scale processing of biological material. Increasingly, biotechnologists are being employed by companies to work in co-operation with chemical engineers to achieve pragmatic commercial goals. For many years aspects of biochemistry and molecular genetics have been included in chemical engineering curricula, yet there has been little attempt until recently to teach aspects of engineering applicable to process design to biotechnologists.This textbook is the first to present the principles of bioprocess engineering in a way that is accessible to biological scientists. Other texts on bioprocess engineering currently available assume that the reader already has engineering training. On the other hand, chemical engineering textbooks do not consider examples from bioprocessing, and are written almost exclusively with the petroleum and chemical industries in mind. This publication explains process analysis from an engineering point of view, but refers exclusively to the treatment of biological systems. Over 170 problems and worked examples encompass a wide range of applications, including recombinant cells, plant and animal cell cultures, immobilised catalysts as well as traditional fermentation systems.* * First book to present the principles of bioprocess engineering in a way that is accessible to biological scientists* Explains process analysis from an engineering point of view, but uses worked examples relating to biological systems* Comprehensive, single-authored* 170 problems and worked examples encompass a wide range of applications, involving recombinant plant and animal cell cultures, immobilized catalysts, and traditional fermentation systems* 13 chapters, organized according to engineering sub-disciplines, are groupled in four sections - Introduction, Material and Energy Balances, Physical Processes, and Reactions and Reactors* Each chapter includes a set of problems and exercises for the student, key references, and a list of suggestions for further reading* Includes useful appendices, detailing conversion factors, physical and chemical property data, steam tables, mathematical rules, and a list of symbols used* Suitable for course adoption - follows closely curricula used on most bioprocessing and process biotechnology courses at senior undergraduate and graduate levels. |
| bioprocess and biosystems engineering: Integrated Bioprocess Engineering Clemens Posten, 2024-07-01 Bioprocess engineering employs microorganisms to produce biological products for medical and industrial applications. The book covers engineering tasks around- the cultivation process in bioreactors including media design, feeding strategies, or cell harvesting. All aspects are described from the conceptual considerations to technical realization and provide insight by detailed explanations, drawings, formulas, and example processes. |
| bioprocess and biosystems engineering: Bioprocess Engineering Bjorn K. Lydersen, Nancy A. D'Elia, Kim L. Nelson, 1994-04-18 Divided into four sections, the first and third reflect the fact that there are two types of equipment required in the plant--one in which the actual product is synthesized or processed such as the fermentor, centrifuge and chromatographic columns; and the other that supplies support for the facility or process including air conditioning, water and waste systems. Part two describes such components as pumps, filters and valves not limited to a certain type of equipment. Lastly, it covers planning and designing the entire facility along with requirements for containment and validation of the process. |
| bioprocess and biosystems engineering: Bioprocess Engineering Michael L. Shuler, Fikret Kargi, 2014 For Senior-level and graduate courses in Biochemical Engineering, and for programs in Agricultural and Biological Engineering or Bioengineering. This concise yet comprehensive text introduces the essential concepts of bioprocessing-internal structure and functions of different types of microorganisms, major metabolic pathways, enzymes, microbial genetics, kinetics and stoichiometry of growth and product information-to traditional chemical engineers and those in related disciplines. It explores the engineering principles necessary for bioprocess synthesis and design, and illustrates the application of these principles to modern biotechnology for production of pharmaceuticals and biologics, solution of environmental problems, production of commodities, and medical applications. |
| bioprocess and biosystems engineering: Control in Bioprocessing Pablo A. López Pérez, Ricardo Aguilar López, Ricardo Femat, 2020-03-03 Closes the gap between bioscience and mathematics-based process engineering This book presents the most commonly employed approaches in the control of bioprocesses. It discusses the role that control theory plays in understanding the mechanisms of cellular and metabolic processes, and presents key results in various fields such as dynamic modeling, dynamic properties of bioprocess models, software sensors designed for the online estimation of parameters and state variables, and control and supervision of bioprocesses Control in Bioengineering and Bioprocessing: Modeling, Estimation and the Use of Sensors is divided into three sections. Part I, Mathematical preliminaries and overview of the control and monitoring of bioprocess, provides a general overview of the control and monitoring of bioprocesses, and introduces the mathematical framework necessary for the analysis and characterization of bioprocess dynamics. Part II, Observability and control concepts, presents the observability concepts which form the basis of design online estimation algorithms (software sensor) for bioprocesses, and reviews controllability of these concepts, including automatic feedback control systems. Part III, Software sensors and observer-based control schemes for bioprocesses, features six application cases including dynamic behavior of 3-dimensional continuous bioreactors; observability analysis applied to 2D and 3D bioreactors with inhibitory and non-inhibitory models; and regulation of a continuously stirred bioreactor via modeling error compensation. Applicable across all areas of bioprocess engineering, including food and beverages, biofuels and renewable energy, pharmaceuticals and nutraceuticals, fermentation systems, product separation technologies, wastewater and solid-waste treatment technology, and bioremediation Provides a clear explanation of the mass-balance–based mathematical modelling of bioprocesses and the main tools for its dynamic analysis Offers industry-based applications on: myco-diesel for implementing quality of observability; developing a virtual sensor based on the Just-In-Time Model to monitor biological control systems; and virtual sensor design for state estimation in a photocatalytic bioreactor for hydrogen production Control in Bioengineering and Bioprocessing is intended as a foundational text for graduate level students in bioengineering, as well as a reference text for researchers, engineers, and other practitioners interested in the field of estimation and control of bioprocesses. |
| bioprocess and biosystems engineering: Chemical and Bioprocess Engineering Ricardo Simpson, Sudhir K. Sastry, 2013-12-04 The goal of this textbook is to provide first-year engineering students with a firm grounding in the fundamentals of chemical and bioprocess engineering. However, instead of being a general overview of the two topics, Fundamentals of Chemical and Bioprocess Engineering will identify and focus on specific areas in which attaining a solid competency is desired. This strategy is the direct result of studies showing that broad-based courses at the freshman level often leave students grappling with a lot of material, which results in a low rate of retention. Specifically, strong emphasis will be placed on the topic of material balances, with the intent that students exiting a course based upon this textbook will be significantly higher on Bloom’s Taxonomy (knowledge, comprehension, application, analysis and synthesis, evaluation, creation) relating to material balances. In addition, this book also provides students with a highly developed ability to analyze problems from the material balances perspective, which leaves them with important skills for the future. The textbook consists of numerous exercises and their solutions. Problems are classified by their level of difficulty. Each chapter has references and selected web pages to vividly illustrate each example. In addition, to engage students and increase their comprehension and rate of retention, many examples involve real-world situations. |
| bioprocess and biosystems engineering: Cell and Tissue Reaction Engineering Regine Eibl, Dieter Eibl, Ralf Pörtner, Gerardo Catapano, Peter Czermak, 2008-09-30 The completion of the Human Genome Project and the rapid progress in cell bi- ogy and biochemical engineering, are major forces driving the steady increase of approved biotech products, especially biopharmaceuticals, in the market. Today mammalian cell products (“products from cells”), primarily monoclonals, cytokines, recombinant glycoproteins, and, increasingly, vaccines, dominate the biopharmaceutical industry. Moreover, a small number of products consisting of in vitro cultivated cells (“cells as product”) for regenerative medicine have also been introduced in the market. Their efficient production requires comprehensive knowledge of biological as well as biochemical mammalian cell culture fundamentals (e.g., cell characteristics and metabolism, cell line establishment, culture medium optimization) and related engineering principles (e.g., bioreactor design, process scale-up and optimization). In addition, new developments focusing on cell line development, animal-free c- ture media, disposables and the implications of changing processes (multi-purpo- facilities) have to be taken into account. While a number of excellent books treating the basic methods and applications of mammalian cell culture technology have been published, only little attention has been afforded to their engineering aspects. The aim of this book is to make a contribution to closing this gap; it particularly focuses on the interactions between biological and biochemical and engineering principles in processes derived from cell cultures. It is not intended to give a c- prehensive overview of the literature. This has been done extensively elsewhere. |
| bioprocess and biosystems engineering: Bioreactor Modeling Jerome Morchain, 2017-10-06 Dynamic simulation of bioreactors is a challenge for both the industrial and academic worlds. Beyond the large number of physical and biological phenomena to be considered and the wide range of scales involved, the central difficulty lies in the need to account for the dynamic behavior of suspended microorganisms. In the case of chemical reactors, knowledge of the thermodynamic equilibrium laws at the interfaces makes it possible to produce macroscopic models by integrating local laws. Microorganisms, on the other hand, have the ability to modulate the rate of substrate assimilation. Moreover, the nature of the biochemical transformations results from a compromise between the needs of the cell and the available resources. This book revisits the modeling of bioreactors using a multi-scale approach. It addresses issues related to mixing, phase-to-phase transfers and the adaptation of microorganisms to variations in concentration, and explores the use of population balances for the simulation of bioreactors. By adopting a multidisciplinary perspective that draws on process engineering, fluid mechanics and microbiology, this book sheds new light on the particularity of bioprocesses in relation to physical and chemical phenomena. - Presents a multiphase description of bioreactor modeling - Includes a combination of concepts issued from different scientific fields to address a practical issue - Provides a detailed description of the population balance concept as applied to biological systems - Covers a set of illustrative examples of the interaction between hydrodynamics and biological response |
| bioprocess and biosystems engineering: Biosystems Engineering: Biofactories for Food Production in the Century XXI Ramon Guevara-Gonzalez, Irineo Torres-Pacheco, 2014-01-24 This book presents new food production systems (for plants and animals) involving agrochemicals that increase in a controlled manner the bioactives content, under greenhouse conditions. Moreover, conception and design of new instrumentation for precision agriculture and aquiculture contributing in food production is also highlighted in this book. |
| bioprocess and biosystems engineering: Food and Industrial Bioproducts and Bioprocessing Nurhan Turgut Dunford, 2012-05-01 Food and Industrial Bioproducts and Bioprocessing describes the engineering aspects of bioprocessing, including advanced food processing techniques and bioproduct development. The main focus of the book is on food applications, while numerous industrial applications are highlighted as well. The editors and authors, all experts in various bioprocessing fields, cover the latest developments in the industry and provide perspective on new and potential products and processes. Challenges and opportunities facing the bioproduct manufacturing industry are also discussed. Coverage is far-reaching and includes: current and future biomass sources and bioprocesses; oilseed processing and refining; starch and protein processing; non-thermal food processing; fermentation; extraction techniques; enzymatic conversions; nanotechnology; microencapsulation and emulsion techniques; bioproducts from fungi and algae; biopolymers; and biodegradable/edible packaging. Researchers and product developers in food science, agriculture, engineering, bioprocessing and bioproduct development will find Food and Industrial Bioproducts and Bioprocessing an invaluable resource. |
| bioprocess and biosystems engineering: Bioprocess Intensification Dirk Holtmann, 2024-07-01 Application of Process Intensification (PI) presents a set of radically innovative principles in process and equipment design, which can bring significant benefits in terms of process efficiency, capital and operating expenses, quality, process safety, and sustainability. Typical approaches in bioprocess intensification are the reduction of the number of production steps, continuous processing, integrated processes, and alternative energy inputs. |
| bioprocess and biosystems engineering: Computational Intelligence Techniques for Bioprocess Modelling, Supervision and Control Maria Carmo Nicoletti, 2009-06-29 Computational Intelligence (CI) and Bioprocess are well-established research areas which have much to offer each other. Under the perspective of the CI area, Biop- cess can be considered a vast application area with a growing number of complex and challenging tasks to be dealt with, whose solutions can contribute to boosting the development of new intelligent techniques as well as to help the refinement and s- cialization of many of the already existing techniques. Under the perspective of the Bioprocess area, CI can be considered a useful repertoire of theories, methods and techniques that can contribute and offer interesting alternative approaches for solving many of its problems, particularly those hard to solve using conventional techniques. Although throughout the past years CI and Bioprocess areas have accumulated substantial specific knowledge and progress has been quick and with a high degree of success, we believe there is still a long way to go in order to use the potentialities of the available CI techniques and knowledge at their full extent, as tools for supporting problem solving in bioprocesses. One of the reasons is the fact that both areas have progressed steadily and have been continuously accumulating and refining specific knowledge; another reason is the high level of technical expertise demanded by each of them. The acquisition of technical skills, experience and good insights in either of the two areas is very demanding and a hard task to be accomplished by any professional. |
| bioprocess and biosystems engineering: Bioprocess Engineering Shijie Liu, 2016-08-29 Bioprocess Engineering: Kinetics, Sustainability, and Reactor Design, Second Edition, provides a comprehensive resource on bioprocess kinetics, bioprocess systems, sustainability, and reaction engineering. Author Dr. Shijie Liu reviews the relevant fundamentals of chemical kinetics, batch and continuous reactors, biochemistry, microbiology, molecular biology, reaction engineering, and bioprocess systems engineering, also introducing key principles that enable bioprocess engineers to engage in analysis, optimization, and design with consistent control over biological and chemical transformations. The quantitative treatment of bioprocesses is the central theme in this book, with more advanced techniques and applications being covered in depth. This updated edition reflects advances that are transforming the field, ranging from genetic sequencing, to new techniques for producing proteins from recombinant DNA, and from green chemistry, to process stability and sustainability. The book introduces techniques with broad applications, including the conversion of renewable biomass, the production of chemicals, materials, pharmaceuticals, biologics, and commodities, medical applications, such as tissue engineering and gene therapy, and solving critical environmental problems. - Includes the mechanistic description of biotransformations and chemical transformations - Provides quantitative descriptions of bioprocesses - Contains extensive illustrative drawings, which make the understanding of the subject easy - Includes bioprocess kinetics and reactor analysis - Contains examples of the various process parameters, their significance, and their specific practical use - Incorporates sustainability concepts into the various bioprocesses |
| bioprocess and biosystems engineering: Control in Bioprocessing Pablo A. López Pérez, Ricardo Aguilar López, Ricardo Femat, 2020-03-10 Closes the gap between bioscience and mathematics-based process engineering This book presents the most commonly employed approaches in the control of bioprocesses. It discusses the role that control theory plays in understanding the mechanisms of cellular and metabolic processes, and presents key results in various fields such as dynamic modeling, dynamic properties of bioprocess models, software sensors designed for the online estimation of parameters and state variables, and control and supervision of bioprocesses Control in Bioengineering and Bioprocessing: Modeling, Estimation and the Use of Sensors is divided into three sections. Part I, Mathematical preliminaries and overview of the control and monitoring of bioprocess, provides a general overview of the control and monitoring of bioprocesses, and introduces the mathematical framework necessary for the analysis and characterization of bioprocess dynamics. Part II, Observability and control concepts, presents the observability concepts which form the basis of design online estimation algorithms (software sensor) for bioprocesses, and reviews controllability of these concepts, including automatic feedback control systems. Part III, Software sensors and observer-based control schemes for bioprocesses, features six application cases including dynamic behavior of 3-dimensional continuous bioreactors; observability analysis applied to 2D and 3D bioreactors with inhibitory and non-inhibitory models; and regulation of a continuously stirred bioreactor via modeling error compensation. Applicable across all areas of bioprocess engineering, including food and beverages, biofuels and renewable energy, pharmaceuticals and nutraceuticals, fermentation systems, product separation technologies, wastewater and solid-waste treatment technology, and bioremediation Provides a clear explanation of the mass-balance–based mathematical modelling of bioprocesses and the main tools for its dynamic analysis Offers industry-based applications on: myco-diesel for implementing quality of observability; developing a virtual sensor based on the Just-In-Time Model to monitor biological control systems; and virtual sensor design for state estimation in a photocatalytic bioreactor for hydrogen production Control in Bioengineering and Bioprocessing is intended as a foundational text for graduate level students in bioengineering, as well as a reference text for researchers, engineers, and other practitioners interested in the field of estimation and control of bioprocesses. |
| bioprocess and biosystems engineering: Biosystems Engineering I Christoph Wittmann, Rainer Krull, 2010-09-03 -Integration of Systems Biology with Bioprocess Engineering: L-Threonine Production by Systems Metabolic Engineering of Escherichia Coli, By Sang Yup Lee and Jin Hwan Park; -Analysis and Engineering of Metabolic Pathway Fluxes in Corynebacterium glutamicum, By Christoph Wittmann; -Systems Biology of Industrial Microorganisms, Marta Papini, Margarita Salazar, and Jens Nielsen; -De Novo Metabolic Engineering and the Promise of Synthetic DNA, By Daniel Klein-Marcuschamer, Vikramaditya G. Yadav, Adel Ghaderi, and Gregory N. Stephanopoulos; -Systems Biology of Recombinant Protein Production in Bacillus megaterium, Rebekka Biedendieck, Boyke Bunk, Tobias Fürich, Ezequiel Franco-Lara, Martina Jahn, and Dieter Jahn; -Extending Synthetic Routes for Oligosaccharides by Enzyme, Substrate and Reaction Engineering; By Jürgen Seibel, Hans-Joachim Jördening, and Klaus Buchholz; -Regeneration of Nicotinamide Coenzymes: Principles and Applications for the Synthesis of Chiral Compounds; By Andrea Weckbecker, Harald Gröger, and Werner Hummel; |
| bioprocess and biosystems engineering: Separation and Purification Technologies in Biorefineries Shri Ramaswamy, Hua-Jiang Huang, Bandaru V. Ramarao, 2013-02-04 Separation and purification processes play a critical role in biorefineries and their optimal selection, design and operation to maximise product yields and improve overall process efficiency. Separations and purifications are necessary for upstream processes as well as in maximising and improving product recovery in downstream processes. These processes account for a significant fraction of the total capital and operating costs and also are highly energy intensive. Consequently, a better understanding of separation and purification processes, current and possible alternative and novel advanced methods is essential for achieving the overall techno-economic feasibility and commercial success of sustainable biorefineries. This book presents a comprehensive overview focused specifically on the present state, future challenges and opportunities for separation and purification methods and technologies in biorefineries. Topics covered include: Equilibrium Separations: Distillation, liquid-liquid extraction and supercritical fluid extraction. Affinity-Based Separations: Adsorption, ion exchange, and simulated moving bed technologies. Membrane Based Separations: Microfiltration, ultrafiltration and diafiltration, nanofiltration, membrane pervaporation, and membrane distillation. Solid-liquid Separations: Conventional filtration and solid-liquid extraction. Hybrid/Integrated Reaction-Separation Systems: Membrane bioreactors, extractive fermentation, reactive distillation and reactive absorption. For each of these processes, the fundamental principles and design aspects are presented, followed by a detailed discussion and specific examples of applications in biorefineries. Each chapter also considers the market needs, industrial challenges, future opportunities, and economic importance of the separation and purification methods. The book concludes with a series of detailed case studies including cellulosic bioethanol production, extraction of algae oil from microalgae, and production of biopolymers. Separation and Purification Technologies in Biorefineries is an essential resource for scientists and engineers, as well as researchers and academics working in the broader conventional and emerging bio-based products industry, including biomaterials, biochemicals, biofuels and bioenergy. |
| bioprocess and biosystems engineering: Computational Intelligence Techniques for Bioprocess Modelling, Supervision and Control Maria Carmo Nicoletti, 2009-07-09 Computational Intelligence (CI) and Bioprocess are well-established research areas which have much to offer each other. Under the perspective of the CI area, Biop- cess can be considered a vast application area with a growing number of complex and challenging tasks to be dealt with, whose solutions can contribute to boosting the development of new intelligent techniques as well as to help the refinement and s- cialization of many of the already existing techniques. Under the perspective of the Bioprocess area, CI can be considered a useful repertoire of theories, methods and techniques that can contribute and offer interesting alternative approaches for solving many of its problems, particularly those hard to solve using conventional techniques. Although throughout the past years CI and Bioprocess areas have accumulated substantial specific knowledge and progress has been quick and with a high degree of success, we believe there is still a long way to go in order to use the potentialities of the available CI techniques and knowledge at their full extent, as tools for supporting problem solving in bioprocesses. One of the reasons is the fact that both areas have progressed steadily and have been continuously accumulating and refining specific knowledge; another reason is the high level of technical expertise demanded by each of them. The acquisition of technical skills, experience and good insights in either of the two areas is very demanding and a hard task to be accomplished by any professional. |
| bioprocess and biosystems engineering: Bioreaction Engineering Principles Jens Nielsen, John Villadsen, Gunnar Lidén, 2012-12-06 This is the second edition of the text Bioreaction Engineering Principles by Jens Nielsen and John Villadsen, originally published in 1994 by Plenum Press (now part of Kluwer). Time runs fast in Biotechnology, and when Kluwer Plenum stopped reprinting the first edition and asked us to make a second, revised edition we happily accepted. A text on bioreactions written in the early 1990's will not reflect the enormous development of experimental as well as theoretical aspects of cellular reactions during the past decade. In the preface to the first edition we admitted to be newcomers in the field. One of us (JV) has had 10 more years of job training in biotechnology, and the younger author (IN) has now received international recognition for his work with the hottest topics of modem biotechnology. Furthermore we are happy to have induced Gunnar Liden, professor of chemical reaction engineering at our sister university in Lund, Sweden to join us as co-author of the second edition. His contribution, especially on the chemical engineering aspects of real bioreactors has been of the greatest value. Chapter 8 of the present edition is largely unchanged from the first edition. We wish to thank professor Martin Hjortso from LSU for his substantial help with this chapter. |
| bioprocess and biosystems engineering: Current Developments in Biotechnology and Bioengineering Christian Larroche, M. Angeles Sanroman, Guocheng Du, Ashok Pandey, 2016-09-17 Current Developments in Biotechnology and Bioengineering: Bioprocesses, Bioreactors and Controls provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends, reviewing industrial biotechnology and bioengineering practices that facilitate and enhance the transition of processes from lab to plant scale, which is becoming increasingly important as such transitions continue to grow in frequency. Focusing on industrial bioprocesses, bioreactors for bioprocesses, and controls for bioprocesses, this title reviews industrial practice to identify bottlenecks and propose solutions, highlighting that the optimal control of a bioprocess involves not only maximization of product yield, but also taking into account parameters such as quality assurance and environmental aspects. - Describes industrial bioprocesses based on the reaction media - Lists the type of bioreactors used for a specific bioprocess/application - Outlines the principles of control systems in various bioprocesses |
| bioprocess and biosystems engineering: Comprehensive Biotechnology , 2011-08-26 The second edition of Comprehensive Biotechnology, Six Volume Set continues the tradition of the first inclusive work on this dynamic field with up-to-date and essential entries on the principles and practice of biotechnology. The integration of the latest relevant science and industry practice with fundamental biotechnology concepts is presented with entries from internationally recognized world leaders in their given fields. With two volumes covering basic fundamentals, and four volumes of applications, from environmental biotechnology and safety to medical biotechnology and healthcare, this work serves the needs of newcomers as well as established experts combining the latest relevant science and industry practice in a manageable format. It is a multi-authored work, written by experts and vetted by a prestigious advisory board and group of volume editors who are biotechnology innovators and educators with international influence. All six volumes are published at the same time, not as a series; this is not a conventional encyclopedia but a symbiotic integration of brief articles on established topics and longer chapters on new emerging areas. Hyperlinks provide sources of extensive additional related information; material authored and edited by world-renown experts in all aspects of the broad multidisciplinary field of biotechnology Scope and nature of the work are vetted by a prestigious International Advisory Board including three Nobel laureates Each article carries a glossary and a professional summary of the authors indicating their appropriate credentials An extensive index for the entire publication gives a complete list of the many topics treated in the increasingly expanding field |
| bioprocess and biosystems engineering: Advances in Biotechnology Research and Application: 2011 Edition , 2012-01-09 Advances in Biotechnology Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biotechnology. The editors have built Advances in Biotechnology Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biotechnology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Biotechnology Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| bioprocess and biosystems engineering: Using the Engineering Literature Bonnie A. Osif, 2016-04-19 With the encroachment of the Internet into nearly all aspects of work and life, it seems as though information is everywhere. However, there is information and then there is correct, appropriate, and timely information. While we might love being able to turn to Wikipedia for encyclopedia-like information or search Google for the thousands of links |
| bioprocess and biosystems engineering: Advances in Food Bioproducts and Bioprocessing Technologies Monica Lizeth Chavez-Gonzalez, Nagamani Balagurusamy, Cristobal Aguilar, 2019-10-16 The book explores and exploits the synergy and boundary between biotechnology, bioprocessing and food engineering. Divided into three parts, Advances in Food Bioproducts and Bioprocessing Technologies includes contributions that deal with new developments in procedures, bioproducts, and bioprocesses that can be given quantitative expression. Its 40 chapters will describe how research results can be used in engineering design, include procedures to produce food additives and ingredients, and discuss accounts of experimental or theoretical research and recent advances in food bioproducts and bioprocessing technologies. |
| bioprocess and biosystems engineering: Hybrid Modeling in Process Industries Jarka Glassey, Moritz von Stosch, 2018-02-01 This title introduces the underlying theory and demonstrates practical applications in different process industries using hybrid modeling. It reviews hybrid modeling approach applicability in wide range of process industries, recommends how to increase hybrid model performance and throw Insights into cost efficient practices in modeling techniques Discusses advance process operation maximizing the benefits of available process knowledge and Includes real-life and practical case studies |
| bioprocess and biosystems engineering: Advances in Biotechnology Research and Application: 2012 Edition , 2012-12-26 Advances in Biotechnology Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biotechnology. The editors have built Advances in Biotechnology Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biotechnology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Biotechnology Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| bioprocess and biosystems engineering: Modern Optimization Modelling Techniques Roberto Cominetti, Francisco Facchinei, Jean B. Lasserre, 2012-08-28 The theory of optimization, understood in a broad sense, is the basis of modern applied mathematics, covering a large spectrum of topics from theoretical considerations (structure, stability) to applied operational research and engineering applications. The compiled material of this book puts on display this versatility, by exhibiting the three parallel and complementary components of optimization: theory, algorithms, and practical problems. The book contains an expanded version of three series of lectures delivered by the authors at the CRM in July 2009. The first part is a self-contained course on the general moment problem and its relations with semidefinite programming. The second part is dedicated to the problem of determination of Nash equilibria from an algorithmic viewpoint. The last part presents congestion models for traffic networks and develops modern optimization techniques for finding traffic equilibria based on stochastic optimization and game theory. |
| bioprocess and biosystems engineering: Alkanes—Advances in Research and Application: 2012 Edition , 2012-12-26 Alkanes—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Alkanes. The editors have built Alkanes—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Alkanes in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Alkanes—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| bioprocess and biosystems engineering: Ionic Liquid-Based Technologies for Environmental Sustainability Mohammad Jawaid, Akil Ahmad, A. Vijaya Bhaskar Reddy, 2021-12-04 Ionic Liquid-based Technologies for Environmental Sustainability explores the range of sustainable and green applications of IL materials achieved in recent years, such as gas solubility, biomass pre-treatment, bio-catalysis, energy storage, gas separation and purification technologies. The book also provides a reference material for future research in IL-based technologies for environmental and energy applications, which are much in-demand due to sustainable, reusable and eco-friendly methods for highly innovative and applied materials. Written by eminent scholars and leading experts from around the world, the book aims to cover the synthesis and characterization of broad range of ionic liquids and their sustainable applications. Chapters provide cutting-edge research with state-of-the-art developments, including the use of IL-based materials for the removal of pharmaceuticals, dyes and value-added metals. - Describes the fundamentals and major applications of ionic liquid materials - Covers up-to-date developments in novel applications of IL materials - Provides practical tips to aid researchers who work on ionic liquid applications |
| bioprocess and biosystems engineering: Microbial Bioprocessing of Agri-food Wastes Gustavo Molina, Minaxi Sharma, Rachid Benhida, Vijai Kumar Gupta, Ramesh Chander Kuhad, 2023-04-28 Microbes are widely used in large-scale industrial processes due to their versatility, easy growing cultivation, kinetic potential, and the ability to generate metabolites with a wide range of potential applications to various commercial sectors, such as the food, pharmaceutical and cosmetic industries, in addition to the potential for agriculture, biomedical, and several others. Among the metabolites of greatest commercial interest, and many obtained on an industrial scale, the wide range of enzymes, biofuels, organic acids, amino acids, vitamins, biopolymers, and many other classes of metabolites. This book is intended for Bioengineers, Biologist, Biochemist, Biotechnologists, microbiologist, food technologist, enzymologist, and related Professionals/ researchers. Explores recent advances in the valorization of agri-food waste Provides technical concepts on the production of various bio-products of commercial interest Discusses the main process conditions to overcome the difficulties of using waste as alternative raw materials Introduces technical-economic details on the advantages and disadvantages of exploring the waste recovery chain Explores the main technological advances in the recovery of residues in functional products |
| bioprocess and biosystems engineering: Iron Ores Bioprocessing Mingming Zhang, 2022-10-19 This book describes leading research in bioengineering for development of novel technologies for ferrous metal extraction. The author includes new developments in molecular biology, biochemistry, microbiology, cell metabolism, and engineering principles and applies them to the conventional iron ore industry - proposing innovative solutions to various industry challenges. The book focuses on applied approaches and describes emerging and established industrial processes, as well as the underlying theory of the process, and the biology of the microorganisms involved. Elaborates on bioprocessing technologies applicable for extraction of ferrous metals using cross-pollination of microbiology and extractive metallurgy; Presents a systematic overview of bioprocessing technologies encompassing laboratory research, pilot scale studies, and industrial process flowsheet design; Provides comprehensive coverage of the engineering principles behind bioprocesses of iron ores including material and energy balances, transport processes, reactions and reactor engineering. |
| bioprocess and biosystems engineering: Advances In Bio-processing Engineering Juming Tang, Harrison Xiusheng Yang, 2002-05-22 This book consists of peer-reviewed articles reporting on the latest developments in several food engineering and agricultural processing laboratories at US land-granted universities. The contributors are leading experts in their respective fields.The topics covered in the book include new food processing technologies (such as high voltage electric field processing and microwave sterilization/pasteurization), conversion of agricultural by-products into high quality refined cellulose or biodegradable plastics, and advances in machine vision inspection and sorting techniques for fruit and vegetable packaging lines. Each chapter begins with a general background review with important references, and ends with the latest results from each research laboratory. |
| bioprocess and biosystems engineering: Integrated Process Modeling, Advanced Control and Data Analytics for Optimizing Polyolefin Manufacturing Y. A. Liu, Niket Sharma, 2023-07-25 Integrated Process Modeling, Advanced Control and Data Analytics for Optimizing Polyolefin Manufacturing Detailed resource on the “Why,” “What,” and “How” of integrated process modeling, advanced control and data analytics explained via hands-on examples and workshops for optimizing polyolefin manufacturing. Integrated Process Modeling, Advanced Control and Data Analytics for Optimizing Polyolefin Manufacturing discusses, as well as demonstrates, the optimization of polyolefin production by covering topics from polymer process modeling and advanced process control to data analytics and machine learning, and sustainable design and industrial practice. The text also covers practical problems, handling of real data streams, developing the right level of detail, and tuning models to the available data, among other topics, to allow for easy translation of concepts into practice. Written by two highly qualified authors, Integrated Process Modeling, Advanced Control and Data Analytics for Optimizing Polyolefin Manufacturing includes information on: Segment-based modeling of polymer processes; selection of thermodynamic methods; estimation of physical properties for polymer process modeling Reactor modeling, convergence tips and data-fit tool; free radical polymerization (LDPE, EVA and PS), Ziegler-Natta polymerization (HDPE, PP, LLPDE, and EPDM) and ionic polymerization (SBS rubber) Improved polymer process operability and control through steady-state and dynamic simulation models Model-predictive control of polyolefin processes and applications of multivariate statistics and machine learning to optimizing polyolefin manufacturing Integrated Process Modeling, Advanced Control and Data Analytics for Optimizing Polyolefin Manufacturing enables readers to make full use of advanced computer models and latest data analytics and machine learning tools for optimizing polyolefin manufacturing, making it an essential resource for undergraduate and graduate students, researchers, and new and experienced engineers involved in the polyolefin industry. |
| bioprocess and biosystems engineering: Sustainable Bioprocessing for a Clean and Green Environment M. Jerold, A. Santhiagu, Rajulapati Sathish Babu, Narasimhulu Korapatti, 2021-09-17 Sustainable Bioprocessing for a Clean and Green Environment: Concepts and Applications highlights the importance of waste to health in which waste is safely converted to value-added products via bioprocess technologies. Providing fundamental concepts and applications, this book also offers readers the methodology behind the operation of a variety of biological processes used in developing valuable products from waste. Features: Discusses synthesis and use of environmentally friendly biobased materials, such as biopolymer films and biobased plasticizers Highlights nanotechnology applications in the treatment of pollution and emphasizes the synthesis of biogenic nanomaterials for environmental remediation Describes the use of biosurfactants and emerging algal technologies, such as applications of microalgae in nutraceuticals and biofuel production Details delignification for lignocellulosic biomass This interdisciplinary book offers researchers and practitioners in chemical engineering, environmental engineering, and related fields a broad perspective on fundamentals, technologies, and environmental applications of sustainable bioprocessing. |
| bioprocess and biosystems engineering: Biotechnology of Microorganisms Jeyabalan Sangeetha, Devarajan Thangadurai, Somboon Tanasupawat, Pradnya Pralhad Kanekar, 2019-05-13 Microbial biotechnology is an important contributor to global business, especially in agriculture, the environment, healthcare, and the medical, food, and chemical industries. This volume provides an exciting interdisciplinary journey through the rapidly changing backdrop of invention in microbial biotechnology, covering a range of topics, including microbial properties and characterization, cultivation and production strategies, and applications in healthcare, bioremediation, nanotechnology, and more. Key features: Explains the diverse aspects of and strategies for cultivation of microbial species Describes biodiversity and biotechnology of microbes Provides an understanding of microorganisms in bioremediation of pollutants Explores various applications of microbes in agriculture, food, health, industry, and the environment Considers production issues and applications of microbial secondary metabolites Underscores the importance of integrating genomics of microorganisms in ecological restoration of contaminated environments |
| bioprocess and biosystems engineering: Issues in Chemical, Biological, and Medical Engineering: 2013 Edition , 2013-05-01 Issues in Chemical, Biological, and Medical Engineering: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Biosystems Engineering. The editors have built Issues in Chemical, Biological, and Medical Engineering: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biosystems Engineering in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Chemical, Biological, and Medical Engineering: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| bioprocess and biosystems engineering: Cell Culture Engineering Wei-Shu Hu, 2006-08-16 Since the introduction of recombinant human growth hormone and insulin a quarter century ago, protein therapeutics has greatly broadened the ho- zon of health care. Many patients suffering with life-threatening diseases or chronic dysfunctions, which were medically untreatable not long ago, can attest to the wonder these drugs have achieved. Although the ?rst generation of p- tein therapeutics was produced in recombinant Escherichia coli, most recent products use mammalian cells as production hosts. Not long after the ?rst p- duction of recombinant proteins in E. coli, it was realized that the complex tasks of most post-translational modi?cations on proteins could only be ef?ciently carried out in mammalian cells. In the 1990s, we witnessed a rapid expansion of mammalian-cell-derived protein therapeutics, chie?y antibodies. In fact, it has been nearly a decade since the market value of mammalian-cell-derived protein therapeutics surpassed that of those produced from E. coli. A common characteristic of recent antibody products is the relatively large dose required for effective therapy, demanding larger quantities for the treatment of a given disease. This, coupled with the broadening repertoire of protein drugs, has rapidly expanded the quantity needed for clinical applications. The increasing demand for protein therapeutics has not been met exclusively by construction of new manufacturing plants and increasing total volume capacity. More - portantly the productivity of cell culture processes has been driven upward by an order of magnitude in the past decade. |
| bioprocess and biosystems engineering: Issues in Chemical, Biological, and Medical Engineering: 2011 Edition , 2012-01-09 Issues in Chemical, Biological, and Medical Engineering: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Chemical, Biological, and Medical Engineering. The editors have built Issues in Chemical, Biological, and Medical Engineering: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Chemical, Biological, and Medical Engineering in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Chemical, Biological, and Medical Engineering: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| bioprocess and biosystems engineering: Carboxylic Ester Hydrolases: Advances in Research and Application: 2011 Edition , 2012-01-09 Carboxylic Ester Hydrolases: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Carboxylic Ester Hydrolases. The editors have built Carboxylic Ester Hydrolases: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Carboxylic Ester Hydrolases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Carboxylic Ester Hydrolases: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
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metabolic engineering arising from genomics, proteomics, and metabolomics have provided new powerful techniques to further understand the physiology of “over-production” and to …
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Bioprocess engineering and technology is primarily associated with the commercial application of living organisms on large scale. Commercialization of biological discoveries requires …
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In addition to institutional requirements, candidates for a BS degree in Biosystems Engineering are required to have a cumulative grade-point average of 2.00 or higher in all engineering …
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complete fundamental calculations, and explain how the concepts are used in industry or by researchers. The concepts section covers basic principles and explains terminology, …
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Biosystems engineers devise practical, eficient solutions for producing, storing, transporting, processing and packaging biological and agricultural products. They solve problems related to …
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Biosystems Engineering 3 BE 4380 Bioprocess Engineering Design 3 CH 2230 Organic Chemistry 1 CH 2270 Organic Chemistry Laboratory 16 SENIOR YEAR 3 BCHM 3050 …
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Biosystems Engineering is a new scientific discipline that applies biological principles to develop new engineering solutions for agriculture, food, forestry, aquaculture, energy, environment, …
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Liu,2012-11-21 Bioprocess Engineering involves the design and development of equipment and processes for the manufacturing of products such as food feed pharmaceuticals nutraceuticals …
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biosystems engineering Biological Engineering (BE) applies engineering principles to protect natural resources and to produce food, biofuels, pharmaceuticals, and other biobased products.
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undergraduate degree in Biosystems Engineering opens the door to a variety of rewarding career options. This handbook is a guide to the curriculum and program.
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Nancy del Pilar Medina Herrera, PhD, is a full-time Professor in the Agronomy School at Autonomous University of Nuevo Leon, Mexico, in the field of bioprocess systems engineering, …
Electrochemically mediated bioconversion and integrated …
Bioprocess and Biosystems Engineering (2023) 46:565–575 https://doi.org/10.1007/s00449-022-02841-6 RESEARCH PAPER Electrochemically mediated bioconversion and integrated …
Cell-surface engineering of yeasts for whole-cell biocatalysts
display technology provides a promising genetic engineering method for implementing the rational redesign of the whole- cell biocatalysts by displaying single or multiple enzymes on
Large-scale crystallization as an intermediate processing
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Analyzing the genetic characteristics of a tryptophan …
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Investigation of the enhancement for Echinocandin B …
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