Clotting Factor Replacement Therapy



  clotting factor replacement therapy: Congenital Bleeding Disorders Akbar Dorgalaleh, 2018-07-25 This book describes in detail the clinical presentation, diagnosis, and management of a wide range of congenital bleeding disorders. It will assist readers in overcoming the significant challenges involved in clinical and laboratory diagnosis and in providing effective clinical care that makes optimal use of new products, including recombinant factor concentrate. The coverage ranges from hemophilia A and B and von Willebrand disease to rare bleeding disorders such as congenital factor V, factor X, factor XI, and factor XIII deficiency and inherited platelet function disorders. The exceptional attention to rarer conditions is of particular importance given the considerable risk of overlooking them during diagnosis, with potential consequences for disease-related morbidity and mortality. The authors are acknowledged specialists in the field from across the world who have particular expertise in the disorder that they discuss. The book will be of value to hematologists, oncologists, pediatricians, laboratory specialists and technicians, general physicians, and trainees.
  clotting factor replacement therapy: Textbook of Hemophilia Christine A. Lee, Erik E. Berntorp, W. Keith Hoots, 2008-04-15 The only up-to-date definitive reference source onhemophilia This book is an invaluable resource that provides an overview ofall aspects of the care of patients with haemophilia. Covering how to assess both bleeding children and adults,Haemophilia A and B, molecular basis of the disease, the role offactors in coagulation, epidemiology, pharmacokinetics, andtreatment of inhibitors. There will also be a section onmusculoskeletal aspects of haemophilia as well as newerdevelopments such as gene therapy and rare bleedingdisorders. Textbook of Hemophilia is ideal for: Trainees and residents in hematology Hematologists in practice Specialists working in thrombosis and hemostasis as well astransfusion medicine Why Buy This Book? The only up-to-date definitive reference source onhemophilia Essential for all those managing hemophilia patients Detailed guidance on assessment, diagnosis, management andtreatment Advice for everyday clinical questions Edited by three of the world’s leading experts onhemophilia
  clotting factor replacement therapy: Continuous Renal Replacement Therapy John A. Kellum, Rinaldo Bellomo, Claudio Ronco, 2016 Continuous Renal Replacement Therapy provides concise, evidence-based, bedside guidance for the management of critically ill patients with acute renal failure, offering quick reference answers to clinicians' questions about treatments and situations encountered in daily practice.
  clotting factor replacement therapy: Trauma Induced Coagulopathy Hunter B. Moore, Matthew D. Neal, Ernest E. Moore, 2020-10-12 The first edition of this publication was aimed at defining the current concepts of trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It served as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader is provided with a full understanding of the tests that are used to study trauma induced coagulopathy. With the growing interest in understanding and managing coagulation in trauma, this second edition has been expanded to 46 chapters from its original 35 to incorporate the massive global efforts in understanding, diagnosing, and treating trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications is reviewed in detail. The text provides therapeutic strategies to treat specific coagulation abnormalities following severe injury, which goes beyond the first edition that largely was based on describing the mechanisms causing coagulation abnormalities. Trauma Induced Coagulopathy 2nd Edition is a valuable reference to clinicians that are faced with specific clinical challenges when managing coagulopathy.
  clotting factor replacement therapy: Transfusion Medicine and Hemostasis Beth H. Shaz, Christopher D. Hillyer, 2013-05-13 The second edition of Transfusion Medicine and Hemostasis continues to be the only pocket-size quick reference for pathology residents and transfusion medicine fellows. It covers all topics in blood banking, transfusion medicine, and clinical and laboratory based coagulation. Short, focused chapters, organized by multiple hierarchical headings, are supplemented with up to 10 suggested reading citations. This single reference covers essentially all the topics required to meet the goals and objectives of a major program in transfusion medicine and clinical coagulation. New chapters in the coagulation testing section reflect the development of new tests available and their incorporation into clinical practice. Coverage includes essential updates on the importance of new cellular therapies, peripheral blood and bone marrow hematopoietic progenitor cells, as well as cord blood banking and regenerative medicine. The authors also examine advances in the understanding of molecular testing and pathogen reduction in two separate quality control chapters (one for blood centers and one for hospitals). - Updated content covers new coagulation tests, cellular therapies, and quality control issues - Easy to use, with focused, well-defined chapters in a standardized format throughout - Offers quick cross-reference lists at the end of each chapter - Includes lists of common abbreviations and indexes that cross reference diagnostic, clinical and therapeutic commonalities
  clotting factor replacement therapy: The Saint-Chopra Guide to Inpatient Medicine Sanjay Saint, Vineet Chopra, 2018 Preceded by: Clinical clerkship in inpatient medicine / Sanjay Saint. 3rd ed. c2010.
  clotting factor replacement therapy: McDonald and Avery's Dentistry for the Child and Adolescent - E-Book Jeffrey A. Dean, 2015-08-10 - UPDATED! More emphasis on preventative care and treatment of medically compromised patients helps you provide more effective care. - NEW! Easier-to-follow design.
  clotting factor replacement therapy: Hemophilia and Von Willebrand Disease David Green, 2018-06-14 Hemophilia and Von Willebrand Disease: Factor VIII and Von Willebrand Factor serves as a must-have reference on the important role these essential blood-clotting proteins play in research and clinical medicine. Clinicians and researchers face the daily challenge of staying current on the vast amounts of research that is now generated. The reference to Janus in the title refers to the two roles of the Factor VIII/Von Willebrand Factor Complex: initiation of coagulation and propagation of clot formation. The complex prevents bleeding in hemophilia and Von Willebrand disease but also augments arterial and venous thrombosis. - Presents one source of information on Hemophilia and Von Willebrand Disease, as well as Factor VIII and Von Willebrand Factor, eliminating the search through hundreds of journal articles - Combines the multi-disciplinary research that is generated from Factor VIII/Von Willebrand Factor – hematology, drug discovery, genetics, cell biology, and oncology - Delves into unanswered questions and future directions of this important blood-clotting complex
  clotting factor replacement therapy: Management of Bleeding Patients Jun Teruya, 2021-01-05 This latest edition provides a comprehensive, state-of-the-art overview of the major issues specific to managing bleeding patients. Like the previous edition, the sections of this new edition have been structured to review the overall scope of issues, among them bleeding associated with disease condition, bleeding from specific organs, bleeding associated with medication, and bleeding associated with procedures. In addition to thoroughly revised and updated chapters from the previous edition, the latest edition features new chapters on such topics as the basics of hemostasis, bleeding due to rare coagulation factor deficiencies, bleeding associated with connective tissue disorders, massive transfusion protocol, bleeding associated with ventricular assist device, and evaluation of bleeding risk prior to invasive procedures. The volume also includes brief etiology and a practical reference guide regarding type of blood components, medication, dose, and duration. Written by authors from a variety of integrated disciplines, Management of Bleeding Patients, Second Edition is a valuable resource for clinicians working in the area of bleeding management.
  clotting factor replacement therapy: Consultative Hemostasis and Thrombosis E-Book Craig S. Kitchens, Barbara A Konkle, Craig M. Kessler, 2013-02-20 A unique clinical focus makes Consultative Hemostasis and Thrombosis, 3rd Edition your go-to guide for quick, practical answers on managing the full range of bleeding and clotting disorders. Emphasizing real-world problems and solutions, Dr. Craig S. Kitchens, Dr. Barbara A. Konkle, and Dr. Craig M. Kessler provide all the clinical guidance you need to make optimal decisions on behalf of your patients and promote the best possible outcomes. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Efficiently look up concise descriptions of each condition, its associated symptoms, laboratory findings, diagnosis, differential diagnosis, and treatment. Get the latest information on hot topics such as Disseminated Intravascular Coagulation, Thrombophilia, Clinical and Laboratory Assessment and Management, Thrombotic -Thrombocytopenic Purpura, and Heparin-Induced Thrombocytopenia. Apply today’s newest therapies, including those that are quickly becoming standard in this fast-changing field. Meet the needs of specific patient groups with a new chapter on Bleeding and the Management of Hemorrhagic Disorders in Pregnancy and an extensively updated chapter on Thrombosis and Cancer. Zero in on key information with a new user-friendly design, and all-new full-color format, abundant laboratory protocols, and at-a-glance tables and charts throughout.
  clotting factor replacement therapy: Anticoagulation Therapy Ozcan Basaran, Murat Biteker, 2016-09-08 The available parenteral and oral anticoagulants have a large clinical use. Understanding biochemistry of anticoagulants may help to improve therapeutic strategies. Resistance to vitamin K antagonist drugs might be a problem for rodent populations. Patients who have thrombogenic risk factors should be anticoagulated. The need for cardiac implantable electronic devices is increasing, and there is a substantial number of patients who are on oral anticoagulant therapy. Prothrombin complex concentrate and other plasma concentrates are useful to deal with over-coagulated situations. The efficacy and safety of non-vitamin K antagonist oral anticoagulants have been proven in large phase III trials. The real-world data suggest even better outcomes with these agents compared to vitamin K antagonists.
  clotting factor replacement therapy: Pediatric Bleeding Disorders Amy L. Dunn, Bryce A. Kerlin, Sarah H. O'Brien, Melissa J. Rose, Riten Kumar, 2020-03-28 This clinical casebook provides a concise, state-of-the-art review of pediatric bleeding disorders. Presented in a case-based format, each case presents a different variant of bleeding disorder, illustrates the etiology, pathology, genetics, diagnosis, and management of the disorder, and offers clinical pearls. Disorders covered include hemophilia A and B, rare factor deficiencies, von Willebrand disease, immune thrombocytopenia purpura, and platelet dysfunctions. Written by experts in the field, Pediatric Bleeding Disorders: A Clinical Casebook is a valuable resource for clinicians and practitioners treating patients with challenging coagulation issues.
  clotting factor replacement therapy: Williams Hematology Hemostasis and Thrombosis Kenneth Kaushansky, Marcel M. Levi, 2018-01-12 Hemostasis and Thrombosis as only Williams can cover them A Doody’s Core Title for 2019! Featuring content derived from Williams Hematology, Ninth Edition. this concise, full-color resource delivers comprehensive and current coverage of hemostasis and thrombosis, and platelet and megakaryocyte disorders. More than a sectional reprint, the book includes updated science and treatment recommendations not found in the 2015 release of Williams Hematology, Ninth Edition. Perfect for use at the point of care, Williams Hemostasis and Thrombosis offers the most current evaluation and treatment options for patients with bleeding and thrombotic disorders. •Covers the latest advances in hemostasis and thrombosis •A handy quick summary appears at the beginning of each chapter •Discusses the physiologic basis for hemostasis and thrombosis
  clotting factor replacement therapy: Hemostasis and Thrombosis Victor J. Marder, William C. Aird, Joel S. Bennett, Sam Schulman, Gilbert C. White, II, 2012-12-27 Since publication of the First Edition in 1982, Hemostasis and Thrombosis has established itself as the pre-eminent book in the field of coagulation disorders. No other book is as inclusive in scope, with coverage of the field from the standpoint of both basic scientists and clinicians. This comprehensive resource details the essentials of bleeding and thrombotic disorders and the management of patients with these and related problems, and delivers the most up-to-date information on normal biochemistry and function of platelets or endothelial cells, as well as in-depth discussions of the pharmacology of anticoagulant, fibrinolytic, and hemostatic drugs. NEW to the Sixth Edition... • A new team of editors, each a leader in his field, assures you of fresh, authoritative perspectives. • Full color throughout • A companion website that offers full text online and an image bank. • A new introductory section of chapters on basic sciences as related to the field • Entirely new section on Hemostatic and Thrombotic Disorders Associated with Systemic Conditions includes material on pediatric patients, women's health issues, cancer, sickle cell disease, and other groups. • Overview chapters preceding each section address broad topics of general importance. This is the tablet version which does not include access to the supplemental content mentioned in the text.
  clotting factor replacement therapy: Blood Banking and Transfusion Medicine Christopher D. Hillyer, Leslie E. Silberstein, Paul M. Ness, Kenneth C. Anderson, John D. Roback, 2006-10-18 Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belongs in your reference library. Integrates scientific foundations with clinical relevance to more clearly explain the science and its application to clinical practice. Highlights advances in the use of blood products and new methods of disease treatment while providing the most up-to-date information on these fast-moving topics Discusses current clinical controversies, providing an arena for the discussion of sensitive topics. Covers the constantly changing approaches to stem cell transplantation and brings you the latest information on this controversial topic.
  clotting factor replacement therapy: Hemophilia and Hemostasis Alice D. Ma, Harold R. Roberts, Miguel A. Escobar, 2012-10-03 There is a general need amongst healthcare professionals for practical advice on the management of patients with bleeding disorders. This book is an essential resource for all those working in the fields of coagulation, hemostasis and thrombosis. It covers the major cases one might encounter in diagnosing, managing and treating hemophilia and hemostasis. It provides a practical and informative guide to the broad range of topics concerning both bleeding and clotting disorders. The book is divided into major chapter sections depending on the type of bleeding disorder it fits into. Each chapter includes a brief overview of the disorder covering: history of the disorder; molecular basis of the disorder; class presentation; genetics; current laboratory tests and monitoring. Cases associated with each disorder are presented alongside practical questions and answers from a wide range of contributors. As practice can vary from center to center, controversial areas are clearly marked and discussed throughout. New to this edition: coverage of the newer techniques; newer treatment modalities; new oral anticoagulants; update on hemophilia management; more on ITP and greater coverage of new cases as suggested by reviewers.
  clotting factor replacement therapy: Haemostasis in Surgery Nadey S. Hakim, Ruben Canelo, 2007 This unique volume presents the cutting edge of haemostasis in surgery and includes the advances in the science pertaining to related important medical and surgical problems. It is the only book that includes all the surgical subspecialties focusing specifically on the problems of haemostasis in each field. State-of-the-art laboratory and clinical reviews are included and modern devices used in the different specialties are also covered. The contributors are well-known authorities in their special fields and haematological area. Each is covered comprehensively with special emphasis on unanswered questions. The book is addressed to all surgeons and physicians with an interest in this exciting field.
  clotting factor replacement therapy: Hemophilia Todd Eckdahl, 2016-10-11 Hemophilia is a genetic disease that impairs the normal process of blood clotting and results in uncontrolled external and internal bleeding. The reader of this book will learn how a diagnosis of hemophilia is made by blood clot­ting tests and measurements of clotting factor levels in blood. The book describes how hemophilia A and B are caused by mutations in genes that encode clotting factor VIII and clotting factor IX, respectively, both of which are carried on the X chromosome. As a result, almost all children born with hemophilia A and B are boys. Hemophilia C is caused by mutations in the clotting factor XI gene on chromosome 4, and occurs in males and females with equal frequency. The author details the use of factor replacement therapy to treat hemophilia, and evaluates the prospects for curing hemophilia through gene therapy and genome editing.
  clotting factor replacement therapy: Core Topics in Critical Care Medicine Fang Gao Smith, Joyce Yeung, 2010-04-22 The critical care unit manages patients with a vast range of disease and injuries affecting every organ system. The unit can initially be a daunting environment, with complex monitoring equipment producing large volumes of clinical data. Core Topics in Critical Care Medicine is a practical, comprehensive, introductory-level text for any clinician in their first few months in the critical care unit. It guides clinicians in both the initial assessment and the clinical management of all CCU patients, demystifying the critical care unit and providing key knowledge in a concise and accessible manner. The full spectrum of disorders likely to be encountered in critical care are discussed, with additional chapters on transfer and admission, imaging in the CCU, structure and organisation of the unit, and ethical and legal issues. Written by Critical Care experts, Core Topics in Critical Care Medicine provides comprehensive, concise and easily accessible information for all trainees.
  clotting factor replacement therapy: NORD Guide to Rare Disorders National Organization for Rare Disorders, 2003 NORD Guide to Rare Disorders is a comprehensive, practical, authoritative guide to the diagnosis and management of more than 800 rare diseases. The diseases are discussed in a uniform, easy-to-follow format--a brief description, signs and symptoms, etiology, related disorders, epidemiology, standard treatment, investigational treatment, resources, and references.The book includes a complete directory of orphan drugs, a full-color atlas of visual diagnostic signs, and a Master Resource List of support groups and helpful organizations. An index of symptoms and key words offers physicians valuable assistance in finding the information they need quickly.
  clotting factor replacement therapy: Cancer-Associated Thrombosis Alok A. Khorana, Charles W. Francis, 2007-09-26 Showcasing the expertise of top-tier specialists who contributed to the newly released guidelines for the care of thrombosis in cancer patients, this exciting guide was written and edited by members of the American Society of Clinical Oncology panel, (ASCO), on the prevention and treatment of cancer-associated thrombosis, among others, and provides
  clotting factor replacement therapy: Human Immunodeficiency Virus Infection in the United States Timothy J. Dondero, 1987
  clotting factor replacement therapy: Surgical Treatment René Holzheimer, John A. Mannick, 2001
  clotting factor replacement therapy: Synopsis of Pediatric Emergency Medicine Gary Robert Fleisher, Stephen Ludwig, Benjamin K. Silverman, 2002 This handbook is a condensed, portable, rapid-reference version of Fleisher and Ludwig's Textbook of Pediatric Emergency Medicine, Fourth Edition, one of the most widely respected books in the field. In a format designed for quick bedside consultation, the Synopsis presents the most essential clinical information from the Textbook's chapters on life-threatening emergencies, signs and symptoms, medical emergencies, trauma, surgical emergencies, and psychosocial emergencies. Each Synopsis chapter covers evaluation, differential diagnosis, physical examination, and management. The 66 signs and symptoms are in alphabetical order and medical emergencies, surgical emergencies, and trauma are organized by body system.
  clotting factor replacement therapy: Essential Concepts in Molecular Pathology William B. Coleman, Gregory J. Tsongalis, 2019-11-23 Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the molecular aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today's advances in pathology and medicine. - Explains the practice of molecular medicine and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine - Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology - Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology
  clotting factor replacement therapy: Linked by Blood: Hemophilia and AIDS David Green, 2016-05-19 Linked by Blood: Hemophilia and AIDS recounts the factors responsible for the widespread infection of people with hemophilia by Human Immunodeficiency Virus (HIV)-contaminated blood and offers a prescription for addressing the challenges of future viral epidemics. The book describes the impact of AIDS on people with hemophilia, their families, and caregivers. The collection, processing, and distribution of blood in the early years of the HIV epidemic are described, including the failure of regulatory agencies to promulgate effective rules to safeguard the blood supply. The contributions of individuals and organizations that mitigated the epidemic are recognized. Linked by Blood presents recommendations for addressing the myriad medical, social, and economic challenges posed by blood-borne viral infections (AIDS, Ebola, MERS) that periodically sweep through large segments of our population. - Addresses the challenges of future viral epidemics - Promotes understanding of the risks and benefits of blood transfusion - Demystifies HIV/AIDS by explaining how the virus causes disease and is detected and treated - Covers the factors that led to contamination of the blood supply and contributed to the AIDS epidemic - Provides background information on hemophilia: who is affected, why they bleed, how it is treated, and what complications can occur - Discusses the role of regulatory agencies in protecting the blood supply and ensuring the safety of blood and blood products - Features new proposals to enhance blood product safety and regulate the prices of blood, drugs, and devices that are essential for human health
  clotting factor replacement therapy: Pediatric Hematology Robert Wynn, Rukhmi Bhat, Paul Monagle, 2017-02-16 A succinct summary of the key principles and facts that guide the everyday practice of modern, clinical paediatric hematology. Covering all the information necessary for examinations in the topic, this book is ideal for postgraduates studying paediatric hematology, as well as for junior doctors in training.
  clotting factor replacement therapy: Burket's Oral Medicine Lester William Burket, Martin S. Greenberg, Michael Glick, 2003 Presenting the status of the fields of oral medicine and clinical oral pathology, this text also outlines the dentist's role in the management of patients with severe medical problems. It reflects the dramatic alterations in some disease patterns as well as the medical advances, which have made an impact on the field of oral medicine. Focusing on knowledge of the pathogenesis and management of diseases, it stresses new diagnostic techniques as well as new concepts of therapy. Chapter topics include the significant research in the field of facial pain management and the impact in oral medicine of such diseases as asthma, chronic obstructive pulmonary disease and tuberculosis. Also examined is the growing importance of geriatrics in dentistry and the issues of Alzheimer's, Parkinson's disease and elderly patients receiving multiple medications. The book includes a CD-ROM with complete text and illustrations.
  clotting factor replacement therapy: Red Book 2015 David W. Kimberlin, MD, FAAP, Sarah S Long, Michael T. Brady, Mary Anne Jackson, 2015-05 The AAP's authoritative guide to the manifestations, etiology, epidemiology, diagnosis, and treatment of more than 200 childhood conditions. -- Provided by publisher.
  clotting factor replacement therapy: Handbook of Clinical Adult Genetics and Genomics Shweta Dhar, Sandesh Sreenath Chakravarthy Nagamani, Tanya Eble, 2020-04-10 Handbook of Clinical Adult Genetics and Genomics: A Practice-Based Approach provides a thorough overview of genetic disorders that are commonly encountered in adult populations and supports the full translation of adult genetic and genomic modalities into clinical practice. Expert chapter authors supplement foundational knowledge with case-based strategies for the evaluation and management of genetic disorders in each organ system and specialty area. Topics discussed include employing genetic testing technologies, reporting test results, genetic counseling for adult patients, medical genetics referrals, issues of complex inheritance, gene therapy, and diagnostic and treatment criteria for developmental, cardiovascular, gastrointestinal, neuropsychiatric, pulmonary issues, and much more. - Employs clinical case studies to demonstrate how to evaluate, diagnosis and treat adult patients with genetic disorders - Offers a practical framework for establishing an adult genetics clinic, addressing infrastructure, billing, counseling, and challenges unique to adult clinical genetics - Features chapter contributions from authors at leading adult genetics institutions in the US and abroad
  clotting factor replacement therapy: Blood Disorders in the Elderly Lodovico Balducci, William Ershler, Giovanni de Gaetano, 2007-12-20 The developed world has an increasingly aging population, with approximately 10% of the population aged over 65 years. As the incidence and prevalence of blood disorders increases with age, these conditions are a heavy burden on healthcare systems. Blood Disorders in the Elderly will provide hematologists, geriatricians and all clinicians involved in the care of patients with blood disorders with clear clinical advice on the diagnosis and management of these conditions. The introductory section reviews epidemiology of aging and anemia and provides a comprehensive approach to the management of cancer in the aging patient. This is followed by a full discussion of hemopoiesis and changes it undergoes in aging. The remaining sections cover the diagnosis and management of all major disorders: anemia, malignancy, coagulation and platelet disorders and hemophilia. A detailed chapter on antithrombotic therapies is also included.
  clotting factor replacement therapy: American Academy of Pediatrics Textbook of Pediatric Care Jane Meschan Foy, 2016-03-31 The definitive manual of pediatric medicine - completely updated with 75 new chapters and e-book access.
  clotting factor replacement therapy: Current Clinical Medicine William Dahill Carey, 2010 Current Clinical Medicine's 2nd edition, by the world famous Cleveland Clinic, is an Internal Medicine reference that gives you authoritative and actionable information wherever you are, whenever you need it. More than 40 updated chapters, 13 new chapters, and 30% new illustrations ensure that you'll have access to the most up-to-date guidance. In addition to its user-friendly, easy-access format and consistent, reliable coverage, this Expert Consult title includes a website with the complete contents of the book, fully searchable, downloadable images, and more, to keep you and your practice completely current. Includes access to a website featuring the complete contents of the book, fully searchable, access to patient information sheets, links to the Gold Standard Drug database, and much more, to keep you completely current. Provides consistent, reliable coverage to keep you on the top of your game. Includes summary boxes and algorithms for quick, confident diagnosis and treatment of each condition. Features a user-friendly format so you can find information quickly and easily. Contains more than a hundred full-color illustrations with a special focus on dermatology for highly visual guidance. Uses evidence-based gradings to help you evaluate your diagnoses. Includes many new chapters-including Hepatocellular Carcinoma, Head and Neck Cancer, Takayasu's Arteritis, and Non-Hodgkin and Hodgkin Lymphoma-as well as more than 40 substantially revised chapters, that ensure that you'll have access to the most current coverage. Features 30% new illustrations that provide you with updated details, concepts, and procedures. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.
  clotting factor replacement therapy: American Society of Hematology Self-Assessment Program Timothy Graubert, James R. Cook, Laura Scheuttpelz, Donald M. Arnold, Adam Cuker, Cindy Neunert, Keith R. McCrae, Margaret Ragni, Sarah O'Brien, Murat Arcasoy, Gary Lyman, Marc J. Kahn, Lawrence A. Solberg, Jecko Thachil, Timothy James Littlewood, Sioban Keel, Charles T. Quinn, Charles H. Packman, Stephan Moll, David Garcia, David P. Steensma, Anjali Sharathkumar, Jorge Di Paola, Amy D. Shapiro, A. Koneti Rao, Charles Eby, Jacob Rand, John Frater, Karen Quillen, Suzanne Bakdash, Dan S. Kaufman, David T. Scadden, Jerald Radich, Sergio Giralt, Geoffrey L. Uy, Inderjeet Dokal, Ross Levine, Ramon V. Tiu, Phillip Scheinberg, Lillian Sung, B. Douglas Smith, Daniel J. DeAngelo, Ching-Hon Pui, Kristie A. Blum, Ann LaCasce, Kerry Joanne Savage, Brad S. Kahl, Grzegorz S. Nowakowski, Vicki A. Morrison, Irene Ghobrial, Martha Lacy, 2013-06-04 Hematologists and others working in hematology-related fields need to stay current with the latest advances in the rapidly evolving disciplines of adult and pediatric hematology. The American Society of Hematology Self-Assessment Program (ASH-SAP) is the only complete, comprehensive, educational resource available that fulfills this need, while also providing thorough board and recertification preparation, as well as AMA PRA Category 1 Credit'.
  clotting factor replacement therapy: Consultative Hemostasis and Thrombosis Craig S. Kitchens, MD, Barbara A Konkle, MD, Craig M. Kessler, MD, 2013-04-18 2014 BMA Medical Book Awards Highly Commended in Internal Medicine category! A unique clinical focus makes Consultative Hemostasis and Thrombosis, 3rd Edition your go-to guide for quick, practical answers on managing the full range of bleeding and clotting disorders. Emphasizing real-world problems and solutions, Dr. Craig S. Kitchens, Dr. Barbara A. Konkle, and Dr. Craig M. Kessler provide all the clinical guidance you need to make optimal decisions on behalf of your patients and promote the best possible outcomes. Efficiently look up concise descriptions of each condition, its associated symptoms, laboratory findings, diagnosis, differential diagnosis, and treatment. Get the latest information on hot topics such as Disseminated Intravascular Coagulation, Thrombophilia, Clinical and Laboratory Assessment and Management, Thrombotic -Thrombocytopenic Purpura, and Heparin-Induced Thrombocytopenia. Apply today's newest therapies, including those that are quickly becoming standard in this fast-changing field. Meet the needs of specific patient groups with a new chapter on Bleeding and the Management of Hemorrhagic Disorders in Pregnancy and an extensively updated chapter on Thrombosis and Cancer. Zero in on key information with a new user-friendly design, and all-new full-color format, abundant laboratory protocols, and at-a-glance tables and charts throughout. Access the entire text and illustrations online - fully searchable - at www.expertconsult.com.
  clotting factor replacement therapy: PSAP 2018 Book 2 Hematology/Immunology/Oncology , 2018-05-15
  clotting factor replacement therapy: Standard Treatment Guidelines—A Manual for Medical Therapeutics, 6e Sangeeta Sharma, GR Sethi, 2021-09-01 Presenting a practical book on managing the patient Why To assist busy clinicians in clinical decision-making To reduce inappropriate clinical variation in practice To improve quality of care and patient safety How User-friendly ready reckoner Holistic approach Up-to-date Evidence-based For Whom General practitioners Primary care physicians Undergraduate medical students Postgraduates and Resident doctors Consultants This clinically oriented book covers more than 330 priority diseases in 11 specialties, focusing on clinical manifestations, therapeutic advances, patient management and patient education. This edition presents you with: Major revisions reflecting latest recommendations in all chapters, and presenting new algorithms. Key information on COVID-19 pandemic: - Restandardized cardio-pulmonary resuscitation algorithms and guidelines in view of the COVID-19 pandemic. - Severe acute respiratory infections (SARI) including COVID-19, management of COVID-19 and co-infections, Pregnancy in COVID-19, etc. A new chapter on tumours and cancers with a special focus on screening and early diagnosis and treatment of some of the most common cancers. Several new priority diseases namely syncope, button battery injuries, acute encephalitis syndrome, cerebral palsy, club foot, scrub typhus, herpes zoster ophthalmicus, frost bite, polycystic ovarian syndrome (PCOS), etc. Antimicrobial Stewardship principles in the treatment of infectious diseases. Large number of experts have contributed in this book to help solve the problems you encounter in everyday practice. This reader friendly, up-to-date and comprehensive book provides expert information you can use immediately in your clinical practice including goals of treatment and assessment of response to therapy with step-up as well as step-down criteria. A busy clinician can thus make an informed, effective patient management decision for different levels of health care, from primary health care to detailed protocols for tertiary care health centres.
  clotting factor replacement therapy: The Management of the Haemophilc Arthropathy Christian Carulli, 2017-06-16 Frontiers in Arthritis is an ebook series devoted to publishing the latest advances in arthritis medicine and research. Each volume brings forth contributions on topics relevant to the diagnosis, management and treatment of arthritis. The ebook series is essential reading for rheumatologists and orthopedic surgeons involved in clinical research and practice. This volume presents comprehensive information about the pathology, diagnosis and treatment of haemophilic arthropathy. Readers will find information about knee, hip, elbow, foot and ankle surgery in patients affected by haemophilia as well as special topics (microsurgery and postoperative rehabilitation and health risks). The broad range of information presented in this volume makes it the definitive handbook on arthritis in haemophiliac cases and the management of related complications.
  clotting factor replacement therapy: Essentials of Emergency Medicine Richard Aghababian, 2010-10-22 This second edition, compiled by an editorial board of veteran emergency medicine providers, draws expert content from 184 contributors. New and updated chapters include expanded sections on pediatrics and toxicology as well as the latest science on emergency psychiatric care. --
  clotting factor replacement therapy: Essentials of Medical Genetics for Health Professionals Laura M. Gunder McClary, Gunder, Scott A. Martin, 2010-09-17 Essentials of Medical Genetics for Health Professionals is a concise, accessible introduction to medical genetics for all health professions students. Even with limited exposure to genetics, students can use the accelerated approach in this text to attain a base foundation of genetics knowledge. This book begins with a review of chromosomes, DNA, RNA, protein synthesis, and inheritance patterns and continues with a clinical focus based on understanding different disease processes. A variety of genetic diseases are explored, including what is known about the genetics involved, the signs and symptoms of the disease, and the treatment options available. Accompanying tables and images aid comprehension. This book also covers diagnostic techniques and an overview of embryonic development and teratogens. The roles of genetic counseling and screening, as well as the ethical and legal issues related to genetic screening and genetic testing are also discussed. Complete with stated objectives, definition of key terms, references, chapter summaries and end of chapter review questions with answers, each chapter is organized for optimal learning. Essentials of Medical Genetics for Health Professionals will not only have application in the classroom setting for health professions or medical students, but practicing clinicians such as physician assistants, nurse practitioners, and physicians who want to learn more or revisit genetics will also find this book a valuable, useful resource. Instructor Resources include PowerPoint Slides, a TestBank, and an Image Bank.
Coagulation - Wikipedia
Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. It results in hemostasis, the cessation of blood loss from a damaged …

Blood Clots - How They Form and Common Causes - WebMD
Nov 19, 2023 · Blood clots are your body's way of stopping you from bleeding too much. Blood has a seemingly impossible job: it must flow continuously and smoothly throughout your body …

Blood Clotting Disorders: Types, Signs and Treatment
Jul 1, 2022 · A blood clotting disorder is a condition that makes your body more likely than normal to make blood clots. You can inherit or acquire one of these conditions. Even if you have a …

Blood Clot: Symptoms, Treatment, Prevention, and More
Apr 3, 2025 · Normal blood clotting is caused by damage that happens to the cells lining your blood vessels. But abnormal blood clotting occurs when there are problems with blood flow.

Blood Clots - Hematology.org
Blood clotting, or coagulation, is an important process that prevents excessive bleeding when a blood vessel is injured. Platelets (a type of blood cell) and proteins in your plasma (the liquid …

How Blood Clots - Blood Disorders - Merck Manual Consumer Version
When clotting is excessive, small blood vessels in critical places can become clogged with clots. Clogged vessels in the brain can cause strokes, and clogged vessels leading to the heart can …

Physiology, Clotting Mechanism - StatPearls - NCBI Bookshelf
Sep 4, 2023 · The human body protects against loss of blood through the clotting mechanism. Vascular mechanisms, platelets, coagulation factors, prostaglandins, enzymes, and proteins …

Coagulation - Wikipedia
Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. It results in hemostasis, the cessation of blood loss from a damaged vessel, …

Blood Clots - How They Form and Common Causes - WebMD
Nov 19, 2023 · Blood clots are your body's way of stopping you from bleeding too much. Blood has a seemingly impossible job: it must flow continuously and smoothly throughout your body for an …

Blood Clotting Disorders: Types, Signs and Treatment
Jul 1, 2022 · A blood clotting disorder is a condition that makes your body more likely than normal to make blood clots. You can inherit or acquire one of these conditions. Even if you have a blood …

Blood Clot: Symptoms, Treatment, Prevention, and More
Apr 3, 2025 · Normal blood clotting is caused by damage that happens to the cells lining your blood vessels. But abnormal blood clotting occurs when there are problems with blood flow.

Blood Clots - Hematology.org
Blood clotting, or coagulation, is an important process that prevents excessive bleeding when a blood vessel is injured. Platelets (a type of blood cell) and proteins in your plasma (the liquid part …

How Blood Clots - Blood Disorders - Merck Manual Consumer Version
When clotting is excessive, small blood vessels in critical places can become clogged with clots. Clogged vessels in the brain can cause strokes, and clogged vessels leading to the heart can …

Physiology, Clotting Mechanism - StatPearls - NCBI Bookshelf
Sep 4, 2023 · The human body protects against loss of blood through the clotting mechanism. Vascular mechanisms, platelets, coagulation factors, prostaglandins, enzymes, and proteins are …