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| cns healthcare depression study pay: Transforming Clinical Research in the United States Institute of Medicine, Board on Health Sciences Policy, Forum on Drug Discovery, Development, and Translation, 2010-10-22 An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical practice and research. There are growing indications, however, that the current health care system and the clinical research that guides medical decisions in the United States falls far short of this vision. The process of generating medical evidence through clinical trials in the United States is expensive and lengthy, includes a number of regulatory hurdles, and is based on a limited infrastructure. The link between clinical research and medical progress is also frequently misunderstood or unsupported by both patients and providers. The focus of clinical research changes as diseases emerge and new treatments create cures for old conditions. As diseases evolve, the ultimate goal remains to speed new and improved medical treatments to patients throughout the world. To keep pace with rapidly changing health care demands, clinical research resources need to be organized and on hand to address the numerous health care questions that continually emerge. Improving the overall capacity of the clinical research enterprise will depend on ensuring that there is an adequate infrastructure in place to support the investigators who conduct research, the patients with real diseases who volunteer to participate in experimental research, and the institutions that organize and carry out the trials. To address these issues and better understand the current state of clinical research in the United States, the Institute of Medicine's (IOM) Forum on Drug Discovery, Development, and Translation held a 2-day workshop entitled Transforming Clinical Research in the United States. The workshop, summarized in this volume, laid the foundation for a broader initiative of the Forum addressing different aspects of clinical research. Future Forum plans include further examining regulatory, administrative, and structural barriers to the effective conduct of clinical research; developing a vision for a stable, continuously funded clinical research infrastructure in the United States; and considering strategies and collaborative activities to facilitate more robust public engagement in the clinical research enterprise. |
| cns healthcare depression study pay: Sleep Disorders and Sleep Deprivation Institute of Medicine, Board on Health Sciences Policy, Committee on Sleep Medicine and Research, 2006-10-13 Clinical practice related to sleep problems and sleep disorders has been expanding rapidly in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and restless legs syndrome are three examples of very common disorders for which we have little biological information. This new book cuts across a variety of medical disciplines such as neurology, pulmonology, pediatrics, internal medicine, psychiatry, psychology, otolaryngology, and nursing, as well as other medical practices with an interest in the management of sleep pathology. This area of research is not limited to very young and old patientsâ€sleep disorders reach across all ages and ethnicities. Sleep Disorders and Sleep Deprivation presents a structured analysis that explores the following: Improving awareness among the general public and health care professionals. Increasing investment in interdisciplinary somnology and sleep medicine research training and mentoring activities. Validating and developing new and existing technologies for diagnosis and treatment. This book will be of interest to those looking to learn more about the enormous public health burden of sleep disorders and sleep deprivation and the strikingly limited capacity of the health care enterprise to identify and treat the majority of individuals suffering from sleep problems. |
| cns healthcare depression study pay: Beyond the HIPAA Privacy Rule Institute of Medicine, Board on Health Care Services, Board on Health Sciences Policy, Committee on Health Research and the Privacy of Health Information: The HIPAA Privacy Rule, 2009-03-24 In the realm of health care, privacy protections are needed to preserve patients' dignity and prevent possible harms. Ten years ago, to address these concerns as well as set guidelines for ethical health research, Congress called for a set of federal standards now known as the HIPAA Privacy Rule. In its 2009 report, Beyond the HIPAA Privacy Rule: Enhancing Privacy, Improving Health Through Research, the Institute of Medicine's Committee on Health Research and the Privacy of Health Information concludes that the HIPAA Privacy Rule does not protect privacy as well as it should, and that it impedes important health research. |
| cns healthcare depression study pay: Lipid Metabolism and Transport in CNS Health and Disease Kimberley D. Bruce, Alfred N. Fonteh, Hussein N. Yassine, 2021-12-07 |
| cns healthcare depression study pay: Animal and Translational Models for CNS Drug Discovery: Neurological Disorders Robert A. McArthur, Franco Borsini, 2008-11-18 Neurological Disorders is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for neurological disorders such as neurofibromatosis, Alzheimer's disease, Parkinson's disease, Huntington disease, ALS, and the epilepsies. Neurological Disorders has introductory chapters expressing the view of the role and relevance of animal models for drug discovery and development for the treatment of psychiatric disorders from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in each therapeutic area covered and discuss the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on Animal and Translational Models for CNS Drug Discovery is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This is the second volume in the three volume-set, Animal and Translational Models for CNS Drug Discovery 978-0-12-373861-5, which is also available for purchase individually. - Clinical, academic, government and industry perspectives fostering integrated communication between principle participants at all stages of the drug discovery process - Critical evaluation of animal and translational models improving transition from drug discovery and clinical development - Emphasis on what results mean to the overall drug discovery process - Exploration of issues in clinical trial design and conductance in each therapeutic area |
| cns healthcare depression study pay: Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics Carl Faingold, Hal Blumenfeld, 2013-12-26 Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: - How the brain carries out important tasks via networks - How these networks interact in normal brain function - Major mechanisms that control network function - The interaction of the normal networks to produce more complex behaviors - How brain disorders can result from abnormal interactions - How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders. - Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant - Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders - Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain - Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available |
| cns healthcare depression study pay: Diagnosis and Treatment of Attention Deficit Hyperactivity Disorder (ADHD). , 1998 |
| cns healthcare depression study pay: The Biopsychosocial Model of Health and Disease Derek Bolton, Grant Gillett, 2019-03-28 This open access book is a systematic update of the philosophical and scientific foundations of the biopsychosocial model of health, disease and healthcare. First proposed by George Engel 40 years ago, the Biopsychosocial Model is much cited in healthcare settings worldwide, but has been increasingly criticised for being vague, lacking in content, and in need of reworking in the light of recent developments. The book confronts the rapid changes to psychological science, neuroscience, healthcare, and philosophy that have occurred since the model was first proposed and addresses key issues such as the model’s scientific basis, clinical utility, and philosophical coherence. The authors conceptualise biology and the psychosocial as in the same ontological space, interlinked by systems of communication-based regulatory control which constitute a new kind of causation. These are distinguished from physical and chemical laws, most clearly because they can break down, thus providing the basis for difference between health and disease. This work offers an urgent update to the model’s scientific and philosophical foundations, providing a new and coherent account of causal interactions between the biological, the psychological and social. |
| cns healthcare depression study pay: DSM-5 Classification American Psychiatric Association, 2015-08-25 This handy DSM-5(R) Classification provides a ready reference to the DSM-5 classification of disorders, as well as the DSM-5 listings of ICD-9-CM and ICD-10-CM codes for all DSM-5 diagnoses. To be used in tandem with DSM-5(R) or the Desk Reference to the Diagnostic Criteria From DSM-5(R), the DSM-5(R) Classification makes accessing the proper diagnostic codes quick and convenient. With the advent of ICD-10-CM implementation in the United States on October 1, 2015, this resource provides quick access to the following: - The DSM-5(R) classification of disorders, presented in the same sequence as in DSM-5(R), with both ICD-9-CM and ICD-10-CM codes. All subtypes and specifiers for each DSM-5(R) disorder are included.- An alphabetical listing of all DSM-5 diagnoses with their associated ICD-9-CM and ICD-10-CM codes.- Separate numerical listings according to the ICD-9-CM codes and the ICD-10-CM codes for each DSM-5(R) diagnosis.- For all listings, any codable subtypes and specifiers are included with their corresponding ICD-9-CM or ICD-10-CM codes, if applicable. The easy-to-use format will prove indispensable to a diverse audience--for example, clinicians in a variety of fields, including psychiatry, primary care medicine, and psychology; coders working in medical centers and clinics; insurance companies processing benefit claims; individuals conducting utilization or quality assurance reviews of specific cases; and community mental health organizations at the state or county level. |
| cns healthcare depression study pay: Recovering the US Mental Healthcare System Meaghan Stacy, Charlie A. Davidson, 2022-02-24 This is a vital resource for anyone looking to better support people with psychosis and serious mental illnesses. |
| cns healthcare depression study pay: Ketamine for Treatment-Resistant Depression Sanjay J. Mathew, Carlos A. Zarate, Jr., 2016-11-25 This book brings together an international group of clinicians and researchers from a broad swath of inter-related disciplines to offer the most up-to-date information about clinical and preclinical research into ketamine and second-generation “ketamine-like” fast-acting antidepressants. Currently available antidepressant medications act through monoaminergic systems, are ineffective for many individuals suffering from depression, and are associated with a delayed onset of peak efficacy of several months. The unexpected emergence of ketamine, an anesthetic N-methyl-D-aspartate (NMDA) receptor antagonist, as a rapid-acting antidepressant has reinvigorated CNS drug discovery research and catalyzed investigation in patient populations historically ignored in antidepressant drug development programs, particularly treatment-resistant patients and those with suicidality. Recent industry and academic research efforts have coalesced to explore NMDA receptor and glutamatergic molecular targets that lack ketamine’s psychotomimetic side effects and abuse liability but retain its rapid onset of efficacy. However, many fundamental questions remain regarding the neurobiological mechanisms underlying ketamine’s rapid antidepressant effects and the puzzling persistence of benefits observed in some patients following a single dose. This book examines how insights from these studies are forging new conceptual models of the neurobiology of stress-related affective, anxiety, and addictive disorders and the nature of treatment resistance. It also discusses how ketamine’s rapid antidepressant effects provide a scientific platform to facilitate innovation in clinical trial designs pertaining to patient selection, choice of control group, outcome measures, and dose-optimization. This book brings together data and insights from this rapidly expanding and extraordinarily promising field of study. Readers will be able to extract integrated themes and useful insights from the material contained in these diverse chapters and appreciate the paradigm-shifting contributions of ketamine to modern psychiatry and clinical neuroscience research. |
| cns healthcare depression study pay: Depression: New Insights for the Healthcare Professional: 2013 Edition , 2013-07-22 Depression: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Depression: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Depression: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| cns healthcare depression study pay: OECD Health Policy Studies Making Mental Health Count The Social and Economic Costs of Neglecting Mental Health Care Hewlett Emily, Moran Valerie, 2014-07-08 This book addresses the high cost of mental illness, the organisation of care, changes and future directions for the mental health workforce, indicators for mental health care and quality, and tools for better governance of the system. |
| cns healthcare depression study pay: Biomedical Index to PHS-supported Research: pt. A. Subject access A-H , 1992 |
| cns healthcare depression study pay: Index Medicus , 2004 Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings. |
| cns healthcare depression study pay: Psychopharmacology Bulletin , 1988 |
| cns healthcare depression study pay: Research Awards Index , 1986 |
| cns healthcare depression study pay: Psychological Considerations in the Young Athlete Melissa A. Christino, Emily I. Pluhar, Lyle J. Micheli, 2023-06-29 This book provides a broad and multidisciplinary review of psychological aspects of sport participation that are important to consider in young athletes. It discusses the many psychosocial benefits of sports, describes common mental health and body image issues pediatric athletes may suffer from, explains the psychological effects of injury and surgery on young athletes and the importance of mind-body connection, and advocates for safe sport participation and a multidisciplinary approach to the care of young athletes. This is the first text to discuss the psychological implications of sport participation in young athletes – a critical topic in today’s sport landscape that is often underappreciated and understudied. Bringing together contributions from prominent sports psychologists, sports medicine physicians and surgeons, coaches, and pain management specialists, Psychological Considerations in the Young Athlete combines the most up-to-date research, and serves as a valuable resource for clinicians, therapists, and athletic trainers who serve pediatric and adolescent athletes and sports teams. |
| cns healthcare depression study pay: Annual Review of Nursing Research, Volume 19, 2001 Joyce J. Fitzpatrick, PhD, MBA, RN, FAAN, Nancy Fugate Woods, PhD, RN, FAAN, 2001-05-16 This book demonstrates that nurses have made an important contribution to the advancement and expansion of women's health knowledge. Selecting the health issues of most importance to women, the editors have assembled leading nurse researchers to review, summarize, and critique nursing research within each area. A general overview of the field is also provided. Contributors include Angela McBride, Linda Andrist, Janice Humphreys, and Jacquelyn Campbell. Also contributing are Kathleen MacPherson and Nancy King Reame, nurse members of the original Boston Women's Health Collective, which authors OUR BODIES, OURSELVES. |
| cns healthcare depression study pay: Toxicology Research Projects Directory , 1980 |
| cns healthcare depression study pay: Research Grants Index National Institutes of Health (U.S.). Division of Research Grants, 1970 |
| cns healthcare depression study pay: Neural Mechanisms Underlying Movement-Based Embodied Contemplative Practices Laura Schmalzl, Catherine E. Kerr, 2016-07-05 Relative to the extensive neuroscientific work on seated meditation practices, far less studies have investigated the neural mechanisms underlying movement-based contemplative practices such as yoga or tai chi. Movement-based practices have, however, been found to be effective for relieving the symptoms of several clinical conditions, and to elicit measurable changes in physiological, neural, and behavioral parameters in healthy individuals. An important challenge for neuroscience is therefore to advance our understanding of the neurophysiological and neurocognitive mechanisms underlying these observed effects, and this Research Topic aims to make a contribution in this regard. It showcases the current state of the art of investigations on movement-based practices including yoga, tai chi, the Feldenkrais Method, as well as dance. Featured contributions include empirical research, proposals of theoretical frameworks, as well as novel perspectives on a variety of issues relevant to the field. This Research Topic is the first of its kind to specifically attempt a neurophysiological and neurocognitive characterization that spans multiple mindful movement approaches, and we trust it will be of interest to basic scientists, clinical researchers, and contemplative practitioners alike. |
| cns healthcare depression study pay: Biomedical Index to PHS-supported Research , 1989 |
| cns healthcare depression study pay: Charney & Nestler's Neurobiology of Mental Illness Dennis S. Charney, Pamela B. Sklar, Eric J. Nestler, Joseph D. Buxbaum, 2018 In the years following publication of the DSM-5(R), the field of psychiatry has seen vigorous debate between the DSM's more traditional, diagnosis-oriented approach and the NIMH's more biological, dimension-based RDoC (research domain criteria) approach. Charney & Nestler's Neurobiology of Mental Illness is an authoritative foundation for translating information from the laboratory to clinical treatment, and its fifth edition extends beyond this reference function to acknowledge and examine the controversies, different camps, and thoughts on the future of psychiatric diagnosis. In this wider context, this book provides information from numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. Sections and chapters are edited and authored by experts at the top of their fields. No other book distills the basic science and underpinnings of mental disorders-and highlights practical clinical significance-to the scope and breadth of this classic text. In this edition, Section 1, which reviews the methods used to examine the biological basis of mental illness in animal and cell models and in humans, has been expanded to reflect critically important technical advances in complex genetics (including powerful sequencing technologies and related bioinformatics), epigenetics, stem cell biology, optogenetics, neural circuit functioning, cognitive neuroscience, and brain imaging. This range of established and emerging methodologies offer groundbreaking advances in our ability to study the brain as well as unique opportunities for the translation of preclinical and clinical research into badly needed breakthroughs in our therapeutic toolkit. Sections 2 through 7 cover the neurobiology and genetics of major psychiatric disorders: psychoses (including bipolar disorder), mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood onset. Also covered within these sections is a summary of current therapeutic approaches for these illnesses as well as the ways in which research advances are now guiding the search for new treatments. Each of these parts has been augmented in several different areas as a reflection of research progress. The last section, Section 8, reconfigured in this new edition, now focuses on diagnostic schemes for mental illness. This includes an overview of the unique challenges that remain in diagnosing these disorders given our still limited knowledge of disease etiology and pathophysiology. The section then provides reviews of DSM-5(R), which forms the basis of psychiatric diagnosis in the United States for all clinical work, and of RDoC, which provides an alternative perspective on diagnosis in heavy use in the research community. Also included are chapters on future efforts toward precision and computational psychiatry, which promise to someday align diagnosis with underlying biological abnormalities. |
| cns healthcare depression study pay: Foundations of Clinical Nurse Specialist Practice Janet S. Fulton, Brenda L. Lyon, Kelly A. Goudreau, 2010 Print+CourseSmart |
| cns healthcare depression study pay: Psychiatric and Mental Health Nursing for Canadian Practice Wendy Austin, Mary Ann Boyd, 2010-01-01 Rev. ed. of: Psychiatric nursing for Canadian practice / Wendy Austin, Mary Ann Boyd. |
| cns healthcare depression study pay: Advances in Systems Biology Igor I. Goryanin, Andrew B. Goryachev, 2011-12-09 The International Society for Systems Biology (ISSB) is a society aimed at advancing world-wide systems biology research by providing a forum for scientific discussions and various academic services. The ISSB helps coordinate researchers to form alliances for meeting the unique needs of multidisciplinary and international systems biology research. The annual International Conference on Systems Biology (ICSB) serves as the main meeting for the society and is one of the largest academic and commercial gatherings under the broad heading of ‘Systems Biology’. |
| cns healthcare depression study pay: Routledge International Handbook of Positive Health Sciences Jolanta Burke, Ilona Boniwell, Beth Frates, Liana S. Lianov, Ciaran A. O’Boyle, 2023-12-27 This ground-breaking book combines research and practice in the rapidly growing field of Positive Psychology with the fastest-growing medical speciality of Lifestyle Medicine. Section 1 maps out the new field of positive health by exploring the scope, content and architecture of this rapidly emerging area of research. It explores research findings and applications derived from Lifestyle Medicine and Positive Psychology that are critical for positive health. Section 2 delves into positive health research, covering topics such as using character strengths to improve health, maximising psychological wellbeing from head to toe, optimising gut health and understanding the relationships between mind and body. Section 3 offers guidance on applying the principles of positive health by describing new Positive Health Interventions (PHIs), introducing innovative positive health coaching models and exploring the contribution of positive psychology to health equity. The book is ideal for medical doctors, nurses and health professionals interested in helping their patients flourish psychologically and physically. It is an invaluable guide for social workers, positive psychologists, coaches and mental health professionals who want to explore the physiological dimensions of wellbeing. |
| cns healthcare depression study pay: Versed Rae Armantrout, 2010-08 A collection of poetry organized in two sections. The first section, Versed, play with vice and versa, the perversity of human consciousness. They flirt with error and delusion, skating on a thin ice that inevitably cracks. The second section, Dark Matter, alludes to more than the unseen substance thought to make up the majority of mass in the universe. The invisible and unknowable are confronted directly as the author's experience with cancer marks these poems with a new austerity, shot through with her signature wit and stark unsentimental thinking.--Résumé de l'éditeur. |
| cns healthcare depression study pay: Psychiatry: An evidence-based text Bassant Puri, Ian Treasaden, 2009-11-27 Succinct, user-friendly, thoroughly referenced and prepared by leading experts in the field, this book is the only single textbook you will need to succeed in the Royal College of Psychiatrists' MRCPsych and other related higher examinations. Chapters follow the structure and syllabus of the examination ensuring that you receive the necessary essen |
| cns healthcare depression study pay: Overcoming Depression 3rd Edition Paul Gilbert, 2009-05-01 Overcoming app now available via iTunes and the Google Play Store. A Books on Prescription Title Break free from the hell of depression If you suffer from depression you are far from alone. Depression is very common, affecting over 300 million people around the world. Written by Professor Paul Gilbert, internationally recognised for his work on depression, this highly acclaimed self-help book has been of benefit to thousands of people including sufferers, their friends and families, and those working in the medical profession. This fully revised third edition has been extensively updated and rewritten to reflect over ten years of new research on understanding and treating depression, particularly the importance of developing compassionate ways of thinking, behaving and feeling. It contains helpful case studies and new, easy-to-follow, step-by-step suggestions and exercises to help you understand your depression and lift your mood. |
| cns healthcare depression study pay: Androgenetic Alopecia From A to Z Konstantinos Anastassakis, 2022-10-26 This second of three related volumes, designed as a reference tool for the understanding and treatment of Androgenetic Alopecia and Female Pattern Hair Loss (AGA/FPHL), is structured in 4 sections: 63 dedicated chapters covering every aspect of medical (non-surgical, non-invasive) and nutritional treatment options and clinical effects. FDA-approved hair growth drugs, every frequently prescribed off-label or experimental drug, hormones, cosmeceuticals, and popular fraudulent controversial products are all presented in 26 chapters, with figures, tables, algorithms, and thousands of fully updated and balanced literature citations. Filling a gap in the latest literature, Androgenetic Alopecia From A to Z: Drugs, Herbs, Nutrition, and Supplements includes a thorough review of lifestyle and nutritional factors specifically affecting AGA/FPHL, including excessive caloric intake, high-fat diets, caloric deprivation, alcohol abuse, and smoking. The intricate effects of nutrition on hair loss, one of the most neglected and misunderstood fields in Dermatology, are presented as well, with a plethora of clinically valuable information: why food supplements are so popular, the regulatory minefield of supplements, and the life-threatening perils of nutritional supplementation, are all reviewed extensively. Each vitamin, major mineral, and trace element implicated in follicular physiology is reviewed in altogether 24 dedicated chapters according to their specific effects on the hair follicle, food sources, dietary recommendations, and the impact of deficiency or excess. This volume includes a comprehensive chapter on the understanding of Complementary-Alternative Medicine (CAM). CAM is an umbrella term for methods that lie outside evidence-based medicine and a part of a societal trend towards the rejection of science as a method of determining facts. The pitfalls and challenges in understanding botanicals with reported hair growth properties, from publication bias to lack of standardization, as well as their unpredictable pharmacological and physiological effects, are all explained in detail. Finally, all popular botanical products reported to possess hair growth properties are appraised in 14 dedicated chapters, each including a detailed review of the general effects, the suggested biochemical mechanisms, claimed actions on the hair follicle, all available studies, and hundreds of literature citations. This carefully crafted book will be an invaluable reference tool for dermatologists and all clinical practitioners dealing with Androgenetic Alopecia and Female Pattern Hair Loss and will help them answer challenging patient questions, debunk myths on hair growth drugs, and supplements and navigate patients towards effective and safe treatment schemes. |
| cns healthcare depression study pay: Drug Therapy in Nursing Diane S. Aschenbrenner, Samantha J. Venable, 2009 This text presents a totally nursing-focused framework for teaching and learning nursing pharmacology, and places the patient at the center of all drug administration decisions and considerations. The book presents core drug knowledge using prototypes of different drug classes and emphasizes core patient variables that influence the patient's response to therapy. This thoroughly updated Third Edition covers newly approved drugs, has separate chapters on drugs affecting fungal and viral infections, and includes more pathophysiology information. FDA Black Box warnings have been added to the discussion of each prototype when applicable, and safety alerts have been added to emphasize prevention of common medication errors. A companion Website offers student and instructor ancillaries including NCLEX®-style questions, pathophysiology animations, medication administration videos, and dosage calculation quizzes. |
| cns healthcare depression study pay: Fluoxetine Graziano Pinna, 2015-04-01 Fluoxetine, best known by the trade name Prozac®, unlike other psychotropic drugs whose effects were serendipitously stumbled upon, was the first developed for a precise mechanism of action, that is, the ability to selectively inhibit serotonin reuptake, based upon the theory that increasing the availability of serotonin would treat major depression. Once approved by the FDA in 1987, fluoxetine quickly became the most prescribed psychotropic drug worldwide and its success in improving mood disorders has triggered the development of a large number of congener molecules, commonly known as SSRIs after their purported mechanism of action. However, a quarter of a century after its development, the idea that fluoxetine asserts its positive behavioral effect through inhibition of serotonergic reuptake is not firmly established. This book reviews several preclinical and clinical reports suggesting that the pharmacological effects of fluoxetine may be mediated by means other than the regulation of serotonin, including the regulation of gene expression, modifying epigenetic mechanisms as well as modifying microRNAs. One of the most prominent mechanisms for the therapeutic relevance of fluoxetine relates to influencing neuroplasticity by enhancing neurotropic factors, including BDNF signaling and altering adult neurogenesis. The ability of fluoxetine to rapidly increase neurosteroid levels accounts for the fast anxiolytic effects of this drug. Fluoxetine action at sigma-1 receptor or modulating glutamatergic neurotransmission as well as the combination of fluoxetine with other psychotropic drugs is discussed in relation to its therapeutic effects. While fluoxetine was primarily prescribed as an antidepressant, this drug currently represents a treatment of choice for a broad spectrum of psychiatric disorders, including post-traumatic stress disorder and a range of anxiety disorders. This drug even possesses analgesic actions and is a valuable therapy for stroke. This book also highlights emerging evidence on the gender-specific effects of fluoxetine, its potential adverse features, including its addiction liability in combination with psychostimulants, and the impact of perinatal fluoxetine exposure. |
| cns healthcare depression study pay: Krause and Mahan's Food and the Nutrition Care Process, 16e, E-Book Janice L Raymond, Kelly Morrow, 2022-07-30 **Selected for Doody's Core Titles® 2024 with Essential Purchase designation in Nutrition** Provide optimal nutritional care with the latest guidelines to evidence-based practice! Krause and Mahan's Food & the Nutrition Care Process, 16th Edition provides an all-in-one resource for the dietetics information you need to care for patients throughout the entire life cycle. With insight from clinical specialists, the book guides you through the steps of assessment, diagnosis and intervention, monitoring, and evaluation. It also covers nutrition in each stage of life, weight management, medical nutrition therapies for conditions and disorders, and the use of nutrition therapies in childhood. From a team of nutrition experts led by Janice L. Raymond and Kelly Morrow, this classic text has been trusted by nurses, nutritionists, and dieticians for since 1952. - UNIQUE! Pathophysiology algorithms and flow charts present the cause, pathophysiology, and medical nutrition management for a variety of disorders and conditions to help you understand illness and provide optimal nutritional care. - Clinical case studies help you translate academic knowledge into practical patient care using a framework of the nutrition care process. - Sample Nutrition Diagnosis boxes present a problem, its etiology, and its signs and symptoms, then conclude with a nutrition diagnosis, providing scenarios you may encounter in practice. - Clinical Insight boxes expand on information in the text, highlight new areas of focus, and contain information on studies and clinical resources. - New Directions boxes suggest areas for further research by spotlighting emerging areas of interest in nutrition care. - Focus On boxes provide thought-provoking information on key nutrition concepts. - Summary boxes highlight CRISPR, the Indigenous food movement, hearing assessment, health disparities, and the Health At Every Size movement, and include a tribute to Dr. George Blackburn, a respected specialist in obesity and nutrition. - Key terms are listed at the beginning of each chapter and bolded within the text. - NEW Infectious Diseases chapter is written by a new author with specific expertise in infectious disease. - NEW Transgender Nutrition chapter is added, from two new authors. - NEW! COVID-19 updates are provided in multiple chapters, each relating to epidemiology and patient care. - NEW! Information on the FODMAP diet is included in the appendix, covering the sugars that may cause intestinal distress. - NEW! Emphasis on diversity, equity, and inclusion is included in all chapters. - NEW! Updated International Dysphagia Diet Standardisation Initiative (IDDSI) information is included in the appendix. - NEW! Updated pregnancy growth charts are added to this edition. - NEW! Updated Healthy People 2030 information is added throughout the book. |
| cns healthcare depression study pay: Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1993 United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies, 1992 |
| cns healthcare depression study pay: Tea in Health and Disease Prevention Victor R Preedy, Vinood Patel, 2024-09-14 While there is a nearly universal agreement that drinking tea can benefit health, information on the benefits or adverse effects of drinking tea is scattered, leaving definitive answers difficult to ascertain. Tea in Health and Disease Prevention, Second Edition, once again addresses this problem, bringing together all the latest and most relevant information on tea and its health effects into one comprehensive resource. This book covers compounds in black, green, and white teas and explores their health implications, first more generally, then in terms of specific organ systems and diseases. With over 75% brand new content, this fully reorganized, updated edition covers a wider range of tea varieties and beneficial compounds found in tea, such as epigallocatechin gallate and antioxidants.Tea in Health and Disease Prevention, Second Edition, is an organized, efficient resource that will help readers find quick answers to questions and will help inspire further studies for those interested in tea research. This is a must-have reference for researchers in food science and nutrition, as well as nutritionists and dieticians. - Covers and compares features, benefits, and potential negative effects of the most important types of tea, including green, black, and white - Identifies therapeutic benefits of teas for new product development - Offers a one stop shop for research in this area, compiling both foundational and cutting-edge topics into one resource - Includes a dictionary of key terms, other health effects of tea or extracts, and a summary point section within each chapter for a quick reference |
| cns healthcare depression study pay: Towards a psychophysiological approach in physical activity, exercise, and sports, volume II Pedro Forte, Daniel Leite Portella, Diogo Monteiro, José Eduardo Teixeira, 2024-07-12 This Research Topic is the second volume of the article collection: Towards a Psychophysiological Approach in Physical Activity, Exercise, and Sports. Please see the first volume here: https://www.frontiersin.org/research-topics/39747/towards-a-psychophysiological-approach-in-physical-activity-exercise-and-sports/magazine. In recent years, there has been an increase in interest in mental health disorders as a result of mediatic coverage of Olympic athletes’ mental health struggles, and also due to the COVID-19 pandemic lockdowns. These phenomena helped to further exacerbate a problem already extensively present in sport and society. Therefore, applying a psychophysiological approach to physical activity, exercise, and sports research has become very popular. Indeed, mental fatigue and mental disorders are not only psychological in origin, but also require an explanation from a psychophysiological perspective due to the effective interconnection between the psychological and physiological dimensions. Psychological variables can also influence performance and the psychophysiological system has a strong effect on the control of physical capacities. Moreover, pacing behaviour, decision-making, self-regulation, and effort perception can also explain the role of the brain in physical activity and exercise management. Thus, the aim of this Research Topic is to share the impact of a psychophysiological approach in physical activity, exercise, and sports. The goal of this Topic is to address the following: • Factors determining performance, including technical/tactical, physiological, cognitive, and psychosocial; • training and competition demand; • training interventions and testing in sports; • acute and chronic effects of training in psychophysiological variables; • coaching in sports; • strength and conditioning, mental health, and performance; • recent developments within sports sciences research. This Research Topic endeavors to explore at specific themes related to physiological stress and mental well-being. Additionally, we aim to provide evidence to coaches and sports scientists highlighting the relationship between training and competition demands, related to performance. We also want to analyze the effects of strength and conditioning training, and coaching effects (acute and chronic) on psychological and physiological. Finally, it is our intention to provide scientific literature with evidence for a relationship between movement, behavior and cognition with physiological performance: the psychophysiological approach. |
| cns healthcare depression study pay: Psychopharmacology Abstracts , 1973 |
| cns healthcare depression study pay: Comorbidity of Mental and Physical Disorders N. Sartorius, R.I.G. Holt, M. Maj, 2014-11-26 This publication presents evidence about the magnitude and severe consequences of comorbidity of mental and physical illnesses from a personal and societal perspective. Leading experts address the huge burden of co-morbidity to the affected individual as well as the public health aspects, the costs to society and interaction with factors stemming from the context of socioeconomic developments. The authors discuss the clinical challenge of managing cardiovascular illnesses, cancer, infectious diseases and other physical illness when they occur with a range of mental and behavioral disorders, including substance abuse, eating disorders and anxiety. Also covered are the organization of health services, the training of different categories of health personnel and the multidisciplinary engagement necessary to prevent and manage comorbidity effectively. The book is essential reading for general practitioners, internists, public health specialists, psychiatrists, cardiologists, oncologists, medical educationalists and other health care professionals. |
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CNS SPECTRUMS
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Pharmacological aspects
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