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| brain stimulation therapy for autism: Switched On John Elder Robison, 2016-03-22 An extraordinary memoir about the cutting-edge brain therapy that dramatically changed the life and mind of John Elder Robison, the New York Times bestselling author of Look Me in the Eye NAMED ONE OF THE BEST BOOKS OF THE YEAR BY THE WASHINGTON POST Imagine spending the first forty years of your life in darkness, blind to the emotions and social signals of other people. Then imagine that someone suddenly switches the lights on. It has long been assumed that people living with autism are born with the diminished ability to read the emotions of others, even as they feel emotion deeply. But what if we’ve been wrong all this time? What if that “missing” emotional insight was there all along, locked away and inaccessible in the mind? In 2007 John Elder Robison wrote the international bestseller Look Me in the Eye, a memoir about growing up with Asperger’s syndrome. Amid the blaze of publicity that followed, he received a unique invitation: Would John like to take part in a study led by one of the world’s foremost neuroscientists, who would use an experimental new brain therapy known as TMS, or transcranial magnetic stimulation, in an effort to understand and then address the issues at the heart of autism? Switched On is the extraordinary story of what happened next. Having spent forty years as a social outcast, misreading others’ emotions or missing them completely, John is suddenly able to sense a powerful range of feelings in other people. However, this newfound insight brings unforeseen problems and serious questions. As the emotional ground shifts beneath his feet, John struggles with the very real possibility that choosing to diminish his disability might also mean sacrificing his unique gifts and even some of his closest relationships. Switched On is a real-life Flowers for Algernon, a fascinating and intimate window into what it means to be neurologically different, and what happens when the world as you know it is upended overnight. Praise for Switched On “An eye-opening book with a radical message . . . The transformations [Robison] undergoes throughout the book are astonishing—as foreign and overwhelming as if he woke up one morning with the visual range of a bee or the auditory prowess of a bat.”—The New York Times “Astonishing, brave . . . reads like a medical thriller and keeps you wondering what will happen next . . . [Robison] takes readers for a ride through the thorny thickets of neuroscience and leaves us wanting more.”—The Washington Post “Fascinating for its insights into Asperger’s and research, this engrossing record will make readers reexamine their preconceptions about this syndrome and the future of brain manipulation.”—Booklist “Like books by Andrew Solomon and Oliver Sacks, Switched On offers an opportunity to consider mental processes through a combination of powerful narrative and informative medical context.”—BookPage “A mind-blowing book that will force you to ask deep questions about what is important in life. Would normalizing the brains of those who think differently reduce their motivation for great achievement?”—Temple Grandin, author of The Autistic Brain “At the heart of Switched On are fundamental questions of who we are, of where our identity resides, of difference and disability and free will, which are brought into sharp focus by Robison’s lived experience.”—Graeme Simsion, author of The Rosie Effect |
| brain stimulation therapy for autism: Look Me in the Eye John Elder Robison, 2008-09-09 NEW YORK TIMES BESTSELLER “As sweet and funny and sad and true and heartfelt a memoir as one could find.” —from the foreword by Augusten Burroughs Ever since he was young, John Robison longed to connect with other people, but by the time he was a teenager, his odd habits—an inclination to blurt out non sequiturs, avoid eye contact, dismantle radios, and dig five-foot holes (and stick his younger brother, Augusten Burroughs, in them)—had earned him the label “social deviant.” It was not until he was forty that he was diagnosed with a form of autism called Asperger’s syndrome. That understanding transformed the way he saw himself—and the world. A born storyteller, Robison has written a moving, darkly funny memoir about a life that has taken him from developing exploding guitars for KISS to building a family of his own. It’s a strange, sly, indelible account—sometimes alien yet always deeply human. |
| brain stimulation therapy for autism: Transcranial Magnetic Stimulation in Clinical Psychiatry Mark S. George, Robert H. Belmaker, 2007-04-02 As understanding evolves about how different brain regions are involved in carrying out everyday tasks -- and in causing brain diseases when they go awry -- this book describes a new technology that allows physicians to focally stimulate the brain in awake adults through a non-invasive procedure. Transcranial Magnetic Stimulation in Clinical Psychiatry is an accessible and authoritative review of TMS, a procedure that is showing promise as a treatment in several disorders. Its authors explain how the procedure works, then the latest findings in a wide range of situations -- notably in depression, but also in other conditions ranging from migraine to stroke recovery. This concise overview of TMS offers practical guidance for psychiatrists and other clinicians using it as a therapy, or referring their patients to have this done, as well as updating the field for neuroscientists and neurologists. It begins with background on the physics and safety of TMS, a guide for administering the procedure, and a review of basic neurophysiological studies with TMS, showing how it can be used to measure connectivity and excitability of the cerebral cortex. The heart of book is then devoted to its clinical applications, organized by disorder: Epilepsy, movement disorders, and pain -- describes the use of TMS in inducing and inhibiting seizures and investigating their pathophysiology; in treating Parkinson's disease; and in relieving pain through motor cortex stimulation Major depression -- provides a critical review of research in the most-studied clinical application of TMS in psychiatry, where it is used as a therapeutic intervention and a neurophysiological probe Mania -- explores the effectiveness of TMS in light of its ECT-like properties through a trial of right TMS vs. sham TMS Anxiety disorders -- reports on investigations on the uses of TMS in treating obsessive-compulsive disorder and posttraumatic stress disorder Schizophrenia -- reviews studies utilizing single- or paired-pulse TMS to assess cortical inhibition and those that explore effects of extended trains of repetitive TMS in altering symptoms A further chapter on TMS in brain imaging shows how integrating imaging and TMS allows one to better place the TMS coil, better understand TMS effects on the brain, and improve understanding of how the brain mediates behavior. With a concluding overview of prospects for the future of repetitive TMS, this volume offers a definitive look at this cutting-edge research and provides critical guidance on how and when clinicians might use TMS in their practice. |
| brain stimulation therapy for autism: Pediatric Brain Stimulation Adam Kirton, Donald L. Gilbert, 2016-05-04 Pediatric Brain Stimulation: Mapping and Modulating the Developing Brain presents the latest on this rapidly expanding field that has seen an exponential growth in publications over the past 10 years. Non-invasive modalities like TMS can painlessly map and measure complex neurophysiology in real patients. Neuromodulatory applications like rTMS and tDCS carry increasingly proven therapeutic applications. Rapidly advancing technological methodologies are increasing opportunities and indications. Despite all these benefits, applications in the more plastic developing brains of children are only just emerging. This book provides a comprehensive overview of brain stimulation in children. Chapters include Transcranial Magnetic Stimulation (TMS) fundamentals, brain stimulation in pediatric neurological conditions, and invasive brain stimulation. The main audience for this research will be those interested in applying brain stimulation technologies to advance clinical research and patient care, although a wide variety of clinicians and scientist will find this to be a valuable reference on brain stimulation with specific chapters on a variety of conditions. - Provides an overview of recent findings and knowledge of pediatric brain stimulation and the developing brain - Edited by renowned leaders in the field of pediatric brain stimulation - Presents a great resource for basic and clinical scientists and practitioners in neuroscience, neurology, neurosurgery, and psychiatry |
| brain stimulation therapy for autism: Oxford Handbook of Transcranial Stimulation Eric Wassermann, Eric Michael Wassermann, Charles Epstein, Ulf Ziemann, 2008-01-24 Transcranial stimulation comprises an important set of techniques for investigating brain function, some of which promise to treat diseases. This book provides a review of the scientific and technical background required to understand transcranial stimulation, for neuroscientists, neurologists, and psychiatrists. |
| brain stimulation therapy for autism: Cognitive Plasticity in Neurologic Disorders Joseph I. Tracy, Benjamin M. Hampstead, K. Sathian, 2014-12-02 This volume makes clear that the cognitive and behavioural symptoms of neurologic disorders and syndromes are dynamic and changing. Each chapter describes the neuroplastic processes at work in a particular condition, giving rise to these ongoing cognitive changes. |
| brain stimulation therapy for autism: Disconnected Kids Robert Melillo, 2009 Offering a bold new understanding of the causes of such disorders as autism, ADHD, Asperger's, dyslexia, and OCD, an effective drug-free program addresses both the symptoms and causes of conditions involving a disconnection between the left and right sides of the developing brain, with customizable exercises, behavior modification advice, nutritional guidelines, and more. |
| brain stimulation therapy for autism: The Safety and Efficacy of Noninvasive Brain Stimulation in Development and Neurodevelopmental Disorders Lindsay M. Oberman, Peter G. Enticott, 2015-12-03 Noninvasive brain stimulation (including Transcranial Magnetic Stimulation (TMS) and Transcranial Current Brain Stimulation (TCS)) can be used both experimentally and therapeutically. In the experimental domain TMS can be applied in single pulses to depolarize a small population of neurons in a targeted brain region. This protocol can be used, for example, to map cortical motor outputs, study central motor conduction time, or evaluate the cortical silent period (a measure of intracortical inhibition) all of which are relevant to neurodevelopment. TMS can also be applied in pairs of pulses (paired pulse stimulation, ppTMS) where two pulses are presented in rapid succession to study intracortical inhibition and facilitation. Trains of repeated TMS (rTMS) pulses can be applied at various stimulation frequencies and patterns to modulate local cortical excitability beyond the duration of the stimulation itself. Depending on the parameters of stimulation the excitability can be either facilitated or suppressed. TCS (including Transcranial Direct Current Stimulation (tDCS), alternating current (tACS), and random noise current stimulation (tRNS) also have the potential to modulate cortical excitability and have also been used to study and modulate cortical activity in healthy and patient populations. The after-effects of rTMS and TCS are thought to be related to changes in efficacy (in either the positive or negative direction) of synaptic connections of the neurons being stimulated, thus these techniques have been used to study and modulate cortical plasticity mechanisms in a number of populations. Recently, researchers have begun to apply these techniques to the study of neurodevelopmental mechanisms as well as the pathophysiology and development of novel treatments for neurodevelopmental disorders. Though there is much promise, caution is warranted given the vulnerability of pediatric and clinical populations and the potential that these techniques have to modify circuit development in a cortex that is in a very dynamic state. This Research Topic hopes to provide an opportunity to share ideas across areas (human and animal researchers, clinicians and basic scientists). We are particularly interested in papers that address issues of choosing a protocol (intensity, frequency, location, coil geometry etc.), populations where noninvasive brain stimulation may have direct impact on diagnostics and treatment, as well as the safety and ethics of applying these techniques in pediatric populations. As many may not be aware of the potential and limitations of noninvasive brain stimulation and its use for research and treatment in this area, this Research Topic promises to have broad appeal. Submissions for all Frontiers article types are encouraged. |
| brain stimulation therapy for autism: Biofeedback for the Brain Paul G. Swingle, 2008 Neurofeedback is a cutting-edge, drug-free therapeutic technique used by over a thousand licensed therapists in North America to treat a range of conditions from attention deficit and hyperactivity disorders to epilepsy, stroke, anxiety, migraine, and depression. First popularized in the 1970s, this naturalistic method is based on the idea that we can control our brain activity and that, through training, the brain can learn to modify its own electrical patterns for more efficient processing or to overcome various states of dysfunction. In Biofeedback for the Brain, Dr. Paul G. Swingle describes in clear and coherent language how these procedures work. With numerous actual case examples, readers follow the progress of clients from the initial brain map that shows the location and severity of the neurological abnormalities to the various stages of treatment. Conditions often considered untreatable by conventional health practitioners respond positively to neurotherapeutic treatment and Swingle describes many of these remarkable recoveries. Other chapters describe the use of neurotherapy for a variety of surprising purposes, including performance training for elite athletes, of which the most famous example is the Italian soccer team who considered the technique to be their secret weapon in attaining a World Cup victory. Despite wide-ranging success stories and the endorsement of the American Psychological Association, many health care practitioners remain skeptical of neurofeedback and the procedures are still not well-known by the public or conventional health care providers. This book provides a thorough, definitive, and highly readable presentation of this remarkable health care alternative that offers millions of individuals a chance for healing. |
| brain stimulation therapy for autism: Defining Autism Emily L. Casanova, Manuel Casanova, 2018-10-18 Offering a summary of the current state of knowledge in autism research, Defining Autism looks at the different genetic, neurological and environmental causes of, and contributory factors to autism. It takes a wide-ranging view of developmental and genetic factors, and considers autism's relationship with other conditions such as epilepsy. Shedding light on the vast number of autism-related syndromes which are all too often denied adequate attention, it shows how, whilst autism refers to a single syndrome, it can be understood as many different conditions, with the common factors being biological, rather than behavioral. |
| brain stimulation therapy for autism: The Comorbidities of Epilepsy Marco Mula, 2019-04-20 Epilepsy is one of most frequent neurological disorders affecting about 50 million people worldwide and 50% of them have at least another medical problem in comorbidity; sometimes this is a the cause of the epilepsy itself or it is due to shared neurobiological links between epilepsy and other medical conditions; other times it is a long-term consequence of the antiepileptic drug treatment. The Comorbidities of Epilepsy offers an up-to-date, comprehensive overview of all comorbidities of epilepsy (somatic, neurological and behavioral), by international authorities in the field of clinical epileptology, with an emphasis on epidemiology, pathophysiology, diagnosis and management. This book includes also a critical appraisal of the methodological aspects and limitations of current research on this field. Pharmacological issues in the management of comorbidities are discussed, providing information on drug dosages, side effects and interactions, in order to enable the reader to manage these patients safely. The Comorbidities of Epilepsy is aimed at all health professionals dealing with people with epilepsy including neurologists, epileptologists, psychiatrists, clinical psychologists, epilepsy specialist nurses and clinical researchers. - Provides a comprehensive overview of somatic, neurological and behavioral co-morbidities of epilepsy - Discusses up-to-date management of comorbidities of epilepsy - Written by a group of international experts in the field |
| brain stimulation therapy for autism: Music Therapy, Sensory Integration and the Autistic Child Dorita S. Berger, 2002 First published in 2002. Routledge is an imprint of Taylor & Francis, an informa company. |
| brain stimulation therapy for autism: Transcranial Magnetic Stimulation Vincent Walsh, Alvaro Pascual-Leone, 2003-06-06 A guide to the use of transcranial magnetic stimulation to reversibly disrupt cortical functioning as a means of studying perceptual and cognitive functions. |
| brain stimulation therapy for autism: Handbook of Transcranial Magnetic Stimulation Alvaro Pascual-Leone, 2001-11-30 Transcranial Magnetic Stimul0tion (TMS) is a non-invasive technique that has revolutionised the study of the human nervous system allowing in-depth investigations of complex voluntary motor control pathways. Today, many of the techniques used in TMS have become routine in clinical electrophysiological assessments. As an investigative tool, its application ranges from clinical diagnostics to cognitive research. Now the use of repetitive TMS (rTMS) is gaining support amongst psychiatrists as evidence suggests that it may provide an alternative to ECT in treating depression and other psychiatric disorders. This handbook brings together the basic science, fundamental principles, and essential procedures of TMS needed by all those useing or planning to use the technique clinically or in research. The final two sections focus upon current up to date knowledge of applications of the technique. Written in a digestible style by world authorities in different related specialties, the Handbook of TMS will be a valuable and comprehensive guide for clinical neurophysiologists, neuropsychiatrists, neurologists and psychiatrists. |
| brain stimulation therapy for autism: Autism Spectrum Disorder Michael Fitzgerald, 2015-04-02 This book starts with a new sub category of Autism Criminal Autistic Psychopathy and school shootings. It focuses on a number of interventions, including speech and language pathology, speech and language assessment instruments, occupational therapy, improving functional language development in autism with natural gestures, communication boards etc as well as helping people with autism using the pictorial support, training of concepts of significant others, theory of mind, social concepts and a conceptual model for empowering families of children with autism cross culturally. It also examines the issue of hyperandrogenism and evidence-based treatments of autism. In terms of assessment, it focuses on psychological and biological assessment including neurotransmitters systems, structural and functional brain imaging, coping strategies of parents, examines the intertwining of language impairment, specific language impairment and ASD, as well as implicit and spontaneous Theory of Mind reading in ASD. In terms of aetiology, it focuses on genetic factors, epigenetics, synaptic vesicles, toxicity during neurodevelopment, immune system and sex differences. It also examines the link between social cognitive anatomical and neurophysiologic biomarkers and candidate genes. This book will be relevant to all mental health professionals because autism occurs in all the different areas of psychiatry and professionals who will find it helpful will be psychiatrists, psychologists, social workers, nurses, teachers and all those working with persons with Autism including parents who nowadays are interested in knowing more and more, at a detailed level about their children or adults with autism. |
| brain stimulation therapy for autism: MacArthur Competence Assessment Tool for Clinical Research (MacCAT-CR) Paul S. Appelbaum, Thomas Grisso, 2001 The MacCAT-CR provides a structured format for capacity assessment that is adaptable to the particulars of any given research project. With the introduction of the MacCAT-CR, researchers enrolling human participants in their studieshave available for the first time a reliable and valid means of assessing their potential subject's capacity to consent to participation. The MacCAT-CR can typically be administered in 15-20 minutes. Beginning with project-specific disclosures to potential participants, the MacCAT-CR measures the four generally accepted components of decision-making competence: understanding, appreciation, reasoning, and the ability to express a choice. Quantification of subjects' responses permits comparisons across subjects and subject groups, and allows the MacCAT-CR to be used for not only for screening individual participants but also for conducting research on the characteristics of subject populations and for assessing the effectiveness of interventions designed to increase subjects' capacities. |
| brain stimulation therapy for autism: Analysis of Pretest-Posttest Designs Peter L. Bonate, 2000-05-12 How do you analyze pretest-posttest data? Difference scores? Percent change scores? ANOVA? In medical, psychological, sociological, and educational studies, researchers often design experiments in which they collect baseline (pretest) data prior to randomization. However, they often find it difficult to decide which method of statistical analysis i |
| brain stimulation therapy for autism: Sleep Disorders in Children Soňa Nevšímalová, Oliviero Bruni, 2016-10-03 This book is both an exam guide to children ́s sleep medicine and a practical manual for diagnosis and management of sleep disorders in children. An overview of the most frequent sleep disorders encountered in newborns, infants, children and adolescents is provided. This book discusses the main sleep disorders in detail, including insomnia, respiratory disturbances, movement disorders during sleep, circadian rhythm disorders, parasomnias, and disorders associated with increased sleepiness. It also covers sleep disorders associated with neurological, psychiatric, and medical diseases. This book is divided into two parts. The first part is an introduction to childhood sleep physiology and pathology, epidemiology of sleep disorders, and diagnostic procedures. The second part describes the most frequent sleep disorders in greater depth. Sleep Disorders in Children is aimed at sleep researchers, pediatricians, child neurologists and child psychiatrists, as well as patient organizations and families with affected children. |
| brain stimulation therapy for autism: Geriatric Forensic Psychiatry Jacob Holzer, Jacob C. Holzer, Robert Kohn, James Ellison, James M. Ellison, Patricia Recupero, Patricia R. Recupero, 2017-12-12 This textbook, one of the first, provides a comprehensive review of the relationship between psychiatry and legal medicine in the older population. Sections reviewing evaluation, civil and criminal topics, and numerous other areas such as risk management, will help physicians, attorneys, and other professionals in their work with the elderly. |
| brain stimulation therapy for autism: Obsessive-compulsive Spectrum Disorders Dan J. Stein, 2006 According to recent estimates, one in 50 adults in the United States has obsessive-compulsive disorder and twice that many have had this disorder at some point in their lives. This issue includes articles on the phenomenology of OCD, hypochondriasis, body dysmorphic disorder, genetics and OCD, trichotillomania, Tourette's syndrome, addictive disorders, pharmacotherapy, psychotherapy, and immunology |
| brain stimulation therapy for autism: Acupuncture for Brain Tianjun Wang, 2020-12-05 This book systematically introduces the Brain in Traditional Chinese Medicine (TCM) and its acupuncture treatments. It discusses the origin and development of the TCM Brain theory, and presents current research on brain and acupuncture, the unique brain related techniques such as scalp acupuncture and Dao-qi technique, the new developing acupuncture treatment methods for brain-related conditions, such as stroke, Parkinson’s, dementia, Alzheimer’s disease, multiple sclerosis, traumatic brain injury, autism, cerebral palsy and depression, anxiety, bipolar disorder among others. This book is of interest to TCM and acupuncture practitioners in the West, as well as acupuncture researchers and lecturers. It gives a new understanding of the brain and treatments for brain-related conditions from a complementary medicine point of view. |
| brain stimulation therapy for autism: Comprehensive Guide to Autism Vinood B. Patel, Victor R. Preedy, Colin R. Martin, 2013-10-15 Autism is a complex multifaceted disorder affecting neurodevelopment during the early years of life and, for many, throughout the life span. Inherent features include difficulties or deficits in communication, social interaction, cognition, and interpersonal behavioral coordination, to name just a few. Autism profoundly impacts the affected individual, the family, and, in many cases, the localized communities. The increased prevalence of childhood autism has resulted in rapid developments in a wide range of disciplines in recent years. Nevertheless, despite intensive research, the cause(s) remain unresolved and no single treatment strategy is employed. To address these issues, Comprehensive Guide to Autism is an all-embracing reference that offers analyses and discussions of contemporary issues in the field of autism. The work brings together scientific material from leading experts in the field relating to a wide range of important current topics, such as the early identification and treatment of children with autism, pertinent social and behavioral studies, recent developments in genetics and immunology, the influence of diet, models of autism, and future treatment prospects. Comprehensive Guide to Autism contains essential readings for behavioral science researchers, psychologists, physicians, social workers, parents, and caregivers. |
| brain stimulation therapy for autism: Electric Brain R. Douglas Fields, 2020-02-04 What is as unique as your fingerprints and more revealing than your diary? Hint: Your body is emitting them right now and has been every single day of your life. Brainwaves. Analyzing brainwaves, the imperceptible waves of electricity surging across your scalp, has been possible for nearly a century. But only now are neuroscientists becoming aware of the wealth of information brainwaves hold about a person's life, thoughts, and future health. From the moment a reclusive German doctor discovered waves of electricity radiating from the heads of his patients in the 1920s, brainwaves have sparked astonishment and intrigue, yet the significance of the discovery and its momentous implications have been poorly understood. Now, it is clear that these silent broadcasts can actually reveal a stunning wealth of information about any one of us. In Electric Brain, world-renowned neuroscientist and author R. Douglas Fields takes us on an enthralling journey into the world of brainwaves, detailing how new brain science could fundamentally change society, separating fact from hyperbole along the way. In this eye-opening and in-depth look at the most recent findings in brain science, Fields explores groundbreaking research that shows brainwaves can: • Reveal the type of brain you have—its strengths and weaknesses and your aptitude for learning different types of information • Allow scientists to watch your brain learn, glean your intelligence, and even tell how adventurous you are • Expose hidden dysfunctions—including signifiers of mental illness and neurological disorders • Render your thoughts and transmit them to machines and back from machines into your brain • Meld minds by telepathically transmitting information from one brain to another • Enable individuals to rewire their own brains and improve cognitive performance Written by one of the neuroscientists on the cutting edge of brainwave research, Electric Brain tells a fascinating and obscure story of discovery, explains the latest science, and looks to the future—and the exciting possibilities in store for medicine, technology, and our understanding of ourselves. |
| brain stimulation therapy for autism: Answering Autism Spencer Doman, Vijay Murthy, Melissa Doman, 2021-06-26 Imagine if you had a practical, step-by-step plan to help your child with autism or ADD make incredible developmental leaps. A plan that could possibly help a child learn to speak, learn and interact with others. For parents of children with autism or ADD, answers can feel impossible to find. This book is full of answers. If you have a child with autism, ADD or another neurodevelopmental delay, Answering Autism will give you a clear plan for every area of your child's development. In this book, you will discover: How to improve your child's speech development The best physical activities to enhance focus, learning ability and speech How to optimize your child's health, diet and sleep A clear program for your child's social development How to teach your kid to read, no matter their age! Answering Autism provides a plan that you can apply immediately to help your child reach their fullest potential |
| brain stimulation therapy for autism: Transcranial Magnetic Stimulation Lucia Alba-Ferrara, 2013 Transcranial Magnetic Stimulation (TMS) is one of the principal research methods used in systems, cognitive and clinical neuroscience. Originally envisioned as a way to measure the responsiveness and conduction speed of neurons and synapses in the brain and spinal cord, TMS has also become an important tool for changing the activity of brain neurons and the functions they underpinned; and as an important adjunct to brain imaging and mapping techniques. Recently, TMS has become a therapeutic technique for neurological as well and psychiatric disorders. This book aims to bring together the basic science, fundamental principles and essential procedures of Transcranial Magnetic Stimulation (TMS), as well as its current and potential clinical applications. The first and second parts of the book present overviews of the principles of TMS, methodological issues in TMS research, the effect of TMS in the brain and its mechanism of action. These chapters also present novel data about cognitive mechanisms in the healthy brain as investigated by using TMS. The next two sections summarise state-of the-art therapeutic uses of TMS in neurological diseases and Psychiatric disorders. TMS use is evaluated in chronic as well as acute conditions. Moreover, novel potential therapeutic interventions are suggested for some diseases in which further research using TMS is warranted. Finally, the use of TMS for children and adolescents with developmental disorders is discussed, and safety protocols for TMS treatment in the developing brain are proposed. This book should be of interest for researchers in neuroscience, neurologists, psychiatrists and psychologists. |
| brain stimulation therapy for autism: Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences Bernardo Dell'Osso, Giorgio Di Lorenzo, 2020-07-31 This book presents the state of the art regarding the use of non-invasive brain stimulation (TMS and tDCS) in the research and treatment of neuropsychiatric disorders. The contributions, all of which were prepared by internationally recognized experts in the field, are divided into two main sections (for TMS and tDCS, respectively) across diagnoses, following an introductory section on the mechanisms of action and neurophysiological background. Neuropsychological perspectives and approaches are provided as well. The book is ultimately intended to offer a unique, integrated approach to the use of non-invasive brain stimulation across the clinical neurosciences, providing a comprehensive and updated perspective that will benefit psychiatrists, neurologists, clinical psychologists and neurophysiologists alike. |
| brain stimulation therapy for autism: Schizophrenia Treatment Yu-Chih Shen, 2016-12-14 Schizophrenia treatment has many facets. This book begins with the glutamatergic and GABAergic hypofunctioning contribute to the schizophrenic symptoms and their current targeted therapeutics. The genetic, epigenetic, and immune etiologies of schizophrenia and their potential targeted therapeutics as approached in this book are interesting. Understanding cognitive biases and delusional circuits in schizophrenia is important; several behavioral cognitive therapies working on the reduction and avoidance of these cognitive biases are demonstrating their effectiveness. Advances in schizophrenia treatment followed, including transcranial magnetic stimulation and special sport program, are presented at the book's end. |
| brain stimulation therapy for autism: High-Functioning Individuals with Autism Eric Schopler, Gary B. Mesibov, 2013-11-11 Designed to advance understanding of the unique needs of high-functioning individuals with autism, this volume details the latest diagnostic and treatment approaches and analyzes the current conceptions of the neurological processes involved in autism. |
| brain stimulation therapy for autism: Autism Spectrum Disorders: Developmental Trajectories, Neurobiological Basis, Treatment Update, Volume 2 Roberto Canitano, Yuri Bozzi, Dirk Dhossche, 2020 This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact. |
| brain stimulation therapy for autism: Autism and the Environment Institute of Medicine, Board on Health Sciences Policy, Forum on Neuroscience and Nervous System Disorders, 2008-03-12 Autism spectrum disorders (ASD) constitute a major public health problem, affecting one in every 150 children and their families. Unfortunately, there is little understanding of the causes of ASD, and, despite their broad societal impact, many people believe that the overall research program for autism is incomplete, particularly as it relates to the role of environmental factors. The Institute of Medicine's Forum on Neuroscience and Nervous System Disorders, in response to a request from the U.S. Secretary of Health and Human Services, hosted a workshop called Autism and the Environment: Challenges and Opportunities for Research. The focus was on improving the understanding of the ways in which environmental factors such as chemicals, infectious agents, or physiological or psychological stress can affect the development of the brain. Autism and the Environment documents the concerted effort which brought together the key public and private stakeholders to discuss potential ways to improve the understanding of the ways that environmental factors may affect ASD. The presentations and discussions from the workshop that are described in this book identify a number of promising directions for research on the possible role of different environmental agents in the etiology of autism. |
| brain stimulation therapy for autism: Brain Connectivity in Autism Rajesh K. Kana, Lucina Q. Uddin, Tal Kenet, Diane Chugani, Ralph-Axel Müller, 2014-09-23 The brain's ability to process information crucially relies on connectivity. Understanding how the brain processes complex information and how such abilities are disrupted in individuals with neuropsychological disorders will require an improved understanding of brain connectivity. Autism is an intriguingly complex neurodevelopmental disorder with multidimensional symptoms and cognitive characteristics. A biological origin for autism spectrum disorders (ASD) had been proposed even in the earliest published accounts (Kanner, 1943; Asperger, 1944). Despite decades of research, a focal neurobiological marker for autism has been elusive. Nevertheless, disruptions in interregional and functional and anatomical connectivity have been a hallmark of neural functioning in ASD. Theoretical accounts of connectivity perceive ASD as a cognitive and neurobiological disorder associated with altered functioning of integrative circuitry. Neuroimaging studies have reported disruptions in functional connectivity (synchronization of activated brain areas) during cognitive tasks and during task-free resting states. While these insights are valuable, they do not address the time-lagged causality and directionality of such correlations. Despite the general promise of the connectivity account of ASD, inconsistencies and methodological differences among studies call for more thorough investigations. A comprehensive neurological account of ASD should incorporate functional, effective, and anatomical connectivity measures and test the diagnostic utility of such measures. In addition, questions pertaining to how cognitive and behavioral intervention can target connection abnormalities in ASD should be addressed. This research topic of the Frontiers in Human Neuroscience addresses “Brain Connectivity in Autism” primarily from cognitive neuroscience and neuroimaging perspectives. |
| brain stimulation therapy for autism: Jasper's Basic Mechanisms of the Epilepsies Jeffrey Noebels, 2012-06-29 Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for a better understanding of the epilepsies and rational methods of prevention and treatment., the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies. |
| brain stimulation therapy for autism: Autism Spectrum Disorders Andreas M. Grabrucker, 2021 Autism spectrum disorders are developmental disorders. Individuals with autism spectrum disorders develop differently. These differences are usually present in social interaction, communication, and sensory processing, and become visible through a wide variety of behavioral responses that differ from individuals without autism spectrum disorders. Despite significant research efforts, the exact causes of autism spectrum disorders remain poorly understood; however, researchers have gained extensive insights into possible pathomechanisms, even at the molecular level of cells. Many diagnostic criteria have been developed, adapted, and improved. The eight chapters in this book highlight the current state-of-the-art in many areas of autism spectrum disorders. Chapter 1 provides an overview of the epidemiology of autism spectrum disorders and the current knowledge of the underlying pathogenic mechanisms. Chapter 2 summarizes the diagnostic criteria and procedures and highlights present and upcoming therapeutic strategies. Chapter 3 reviews the adverse events and trauma in people with autism spectrum disorders. Chapters 4 and 5 focus on atypical sensory processing, and Chapter 6 discusses the genetic overlap of autism spectrum disorders with other neuropsychiatric disorders such as attention deficit hyperactivity disorder (ADHD), depression, and schizophrenia. Chapter 7 focuses on the contribution of abnormalities in mitochondria, and chapter 8 discusses gut-brain interactions and a potential role for microbiota in autism spectrum disorders. This book is aimed primarily at clinicians and scientists, but many areas will also be of interest to the layperson. |
| brain stimulation therapy for autism: Autism Spectrum Disorders David Amaral, Daniel Geschwind, Geraldine Dawson, 2011-05-01 Autism is an emerging area of basic and clinical research, and has only recently been recognized as a major topic in biomedical research. Approximately 1 in 150 children are diagnosed as autistic, so it is also an intense growth area in behavioral and educational treatments. Financial resources have begun to be raised for more comprehensive research and an increasing number of scientists are becoming involved in autism research. In many respects, autism has become a model for conducting translational research on a psychiatric disorder. This text provides a comprehensive summary of all current knowledge related to the behavioral, experiential, and biomedical features of the autism spectrum disorders including major behavioral and cognitive syndromology, common co-morbid conditions, neuropathology, neuroimmunology, and other neurological correlates such as seizures, allergy and immunology, gastroenterology, infectious disease, and epidemiology. Edited by three leading researchers, this volume contains over 80 chapters and nine shorter commentaries by thought leaders in the field, making the book a virtual who's who of autism research. This carefully developed book is a comprehensive and authoritative reference for what we know in this area as well as a guidepost for the next several years in all areas of autism research. |
| brain stimulation therapy for autism: The Routledge Handbook of Philosophy of Skill and Expertise Ellen Fridland, Carlotta Pavese, 2020-08-20 Philosophical questions surrounding skill and expertise can be traced back as far as Ancient Greece, China, and India. In the twentieth century, skilled action was an important factor in the work of phenomenologists such as Heidegger and Merleau-Ponty and analytic philosophers including Gilbert Ryle. However, as a subject in its own right it has, until now, remained largely in the background. The Routledge Handbook of Philosophy of Skill and Expertise is an outstanding reference source and the first major collection of its kind, reflecting the explosion of interest in the topic in recent years. Comprising thirty-nine chapters written by leading international contributors, the Handbook is organized into six clear parts: • Skill in the history of philosophy (East and West) • Skill in epistemology • Skill, intelligence, and agency • Skill in perception, imagination, and emotion • Skill, language, and social cognition • Skill and expertise in normative philosophy. Essential reading for students and researchers in philosophy of mind and psychology, epistemology, and ethics, The Routledge Handbook of Philosophy of Skill and Expertise is also suitable for those in related disciplines such as social psychology and cognitive science. It is also relevant to those who are interested in conceptual issues underlying skill and expertise in fields such as sport, the performing arts, and medicine. |
| brain stimulation therapy for autism: Naturalistic Developmental Behavioral Interventions for Autism Spectrum Disorder Yvonne Bruinsma, Dr Mendy Minjarez, PH D, Laura Schreibman, Dr Aubyn Stahmer, PH D, 2020 This book is the first to offer a comprehensive overview of Naturalistic Developmental Behavioral Interventions (NDBI), which are evidence-based interventions that integrate both behavioral and developmental approaches in the treatment of children with Autism Spectrum Disorder. |
| brain stimulation therapy for autism: How Does Brain Stimulation Work? Neuroversion and Other Putative Mechanisms of Action , 2024-10-10 The field of brain stimulation/neuromodulation has experienced exponential growth in the last decade, with increasing clinical applications in medical specialties, namely psychiatry and neurology. Electroconvulsive therapy (ECT) is the oldest and best-known neuromodulation technique, with a wide application in various psychiatric disorders such as bipolar disorder, major depression, catatonia, psychotic symptoms, and suicidal ideation. However, almost a century after its introduction, its exact mechanisms of action remain unknown. Other techniques such as Deep Brain Stimulation (DBS), initially used in the treatment of tremors and Parkinson's disease, and later expanded to other neurological pathologies, have also been studied and applied in the treatment of mental disorders such as treatment-resistant Obsessive-Compulsive Disorder (trOCD) and treatment-resistant Depression (trD). Transcranial Magnetic Stimulation (TMS) is another neuromodulation technique that has seen remarkable growth in recent years, particularly in treating psychiatric pathologies, namely trD. However, these techniques' exact mechanisms of action are still unknown. In addition to these three main techniques, there are many others, including transcranial direct current stimulation (tDCS), Vagal Nerve Stimulation (VNS), Magnetic Seizure Therapy (MST), and several other emerging techniques. Nevertheless, their exact mechanisms of action in treating neuropsychiatric pathologies are also unknown. |
| brain stimulation therapy for autism: Neuromodulation in Psychiatry Clement Hamani, Paul Holtzheimer, Andres M. Lozano, Helen Mayberg, 2016-01-26 Edited by an expert multidisciplinary team, Neuromodulation in Psychiatry is the first reference guide to address both invasive and non-invasive neuromodulation strategies used in psychiatry. Covers basic principles, technical aspects, clinical applications and ethical considerations Presents up-to-date evidence in comprehensive summaries suitable for all levels of experience Each technique is clearly explained along with its implications for real-world clinical practice Allows psychiatrists to make informed decisions regarding neuromodulation for their patients |
| brain stimulation therapy for autism: Autism Dominic Bucciarelli Kasony MS Ph.D. Licensed-Certified Psychologist, 2021-12-01 Autism: A Practical Guide for Parents was written from the perspective of a father of children (now adults) with disabilities and who is also a licensed and certified psychologist and counselor. When parents are faced with serious medical problems in their children, they become very gullible to exaggerated claims of cure and unethical providers. The book contains substantial information about behavioral interventions to help mediate the behavioral concerns for children with autism, including an extensive reading list to help supplement the parents’ working knowledge and interventions. Also, a section is dedicated to various (and at times erroneous) interventions, including chelation, transcranial magnetic therapy, light therapy, and others. A research section is included to emphasize the importance of psychometric testing and review for the development of reliable and valid testing assessment vehicles. A psychological approach to the understanding of autism begins with a specific perspective of this challenge. First of all, children are children, including those children with autism. Second, you need to be educated about a broad spectrum of autism symptoms, including behavioral, medical, speech and language, and physical. Also, you need to join with a behavioral health team, including a psychologist, behavioral specialist, therapeutic staff support, and/or mobile therapist through your local managed care organization. Remember, you can help make positive behavioral and emotional health changes in your child to help him/her achieve a happy, healthy, and productive life. I have organized this book to be an easy read for parents and professionals. I’m sure you wouldn’t want to read about the abstract details of existential phenomenology, but would rather let me help you understand the details of autistic behavior from the viewpoint of a psychologist and father. I hope I have succeeded in this task! |
| brain stimulation therapy for autism: Modern Approaches to Augmentation of Brain Function Ioan Opris, Mikhail A. Lebedev, Manuel F. Casanova, 2021-08-25 This book covers recent advances in neural technology that provide for enhancements for brain function. It addresses a broad range of neural phenomena occurring in the brain circuits involved in perception, cognition, emotion and action, that represent the building blocks of behavior and cognition. Augmentation of brain function can be achieved by using brain implants for recordings, stimulation, or drug delivery. Alternative methods include employing brain-machine interfaces, as well as noninvasive activation of certain brain areas. This volume evaluates existing methods of brain augmentation while discussing the brain circuitry and neuronal mechanisms that make augmentation possible. This volume offers novel insights into brain disorders, and explores new devices for brain repair while also addressing the philosophical and ethical implications of brain augmentation. The information in this book is relevant to researchers in the fields of neuroscience, engineering, and clinical practice. Advance Praise for Modern Approaches to Augmentation of Brain Function: “This impressive book by leading experts in neuroscience and neuroengineering lays out the future of brain augmentation, in which the human mind and machine merge, leading to a rapid exponential growth of the power of humanity.” Ray Kurzweil, best-selling author, inventor, entrepreneur and a recipient of the National Medal of Technology and Innovation (1999), and the Lemelson-MIT Prize (2001) This book employs a holistic approach in covering the recent advances in the fields of neuroscience, neuroinformatics, neurotechnology and neuro-psycho-pharmacology. Each chapter of the book covers major aspects of modern brain research in connection with the human mind and behavior, and is authored by researchers with unique expertise in their field. Ioan Dumitrache, Prof. Dr. Eng. Faculty of Computer Science, Polytechnic University of Bucharest, Bucharest, Romania “This book presents compelling perspectives on what interactive neuroscience will look like in the future, delving into the innovatory ideas of a diverse set of neuroscientists, and speculating on the different ways computer chips implanted in the brains of humans can effect intelligence and communication.” György Buzsáki, MD, PhD is the Biggs Professor of Neuroscience, NYU School of Medicine, New York, NY |
Brain Anatomy and How the Brain Works | Johns Hopkins Medicine
The brain is a complex organ that controls thought, memory, emotion, touch, motor skills, vision, breathing, temperature, hunger and every process that regulates our body. Together, the brain …
Human brain - Wikipedia
The human brain is the central organ of the nervous system, and with the spinal cord, comprises the central nervous system. It consists of the cerebrum, the brainstem and the cerebellum. …
Brain: Parts, Function, How It Works & Conditions - Cleveland Clinic
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Brain | Definition, Parts, Functions, & Facts | Britannica
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Brain Basics: Know Your Brain | National Institute of Neurological ...
This fact sheet is a basic introduction to the human brain. It can help you understand how the healthy brain works, how to keep your brain healthy, and what happens when the brain doesn't …
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Parts of the Brain: A Complete Guide to Brain Anatomy and …
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How Does the Human Brain Work? - Caltech Science Exchange
Explore the intricate workings of the human brain, from neurons and glia to the central and peripheral nervous systems. Learn how sensory input, emotions, and memories shape our …
Brain Anatomy and How the Brain Works | Johns Hopkins Medicine
The brain is a complex organ that controls thought, memory, emotion, touch, motor skills, vision, breathing, temperature, hunger and every process that regulates our body. Together, the brain …
Human brain - Wikipedia
The human brain is the central organ of the nervous system, and with the spinal cord, comprises the central nervous system. It consists of the cerebrum, the brainstem and the cerebellum. The brain …
Brain: Parts, Function, How It Works & Conditions - Cleveland Clinic
Jan 25, 2025 · Your brain has a really important job, and it often goes unnoticed. Right now, you’re using your brain to read this text. At the same time, your brain is running your body’s motor to …
Brain | Definition, Parts, Functions, & Facts | Britannica
4 days ago · Brain, the mass of nerve tissue in the anterior end of an organism. The brain integrates sensory information and directs motor responses; in higher vertebrates it is also the center of …
Brain Basics: Know Your Brain | National Institute of Neurological ...
This fact sheet is a basic introduction to the human brain. It can help you understand how the healthy brain works, how to keep your brain healthy, and what happens when the brain doesn't …
Parts of the Brain: Neuroanatomy, Structure & Functions in …
May 12, 2025 · The human brain is a complex organ, made up of several distinct parts, each responsible for different functions. The cerebrum, the largest part, is responsible for sensory …
Parts of the Brain and Their Functions - Science Notes and Projects
Feb 20, 2024 · How much of our brain do we use? The myth that humans only use 10% of their brain is false. Virtually every part gets use, and most of the brain is active all the time, even during sleep.
The human brain: Parts, function, diagram, and more - Medical News Today
Feb 10, 2023 · The brain is made up of three main parts, which are the cerebrum, cerebellum, and brain stem. Each of these has a unique function and is made up of several parts as well.
Parts of the Brain: A Complete Guide to Brain Anatomy and Functions
Nov 6, 2024 · The brain can be classified into three major regions — the cerebrum, cerebellum, and the brainstem, each responsible for essential activities like movement, balance, and autonomic …
How Does the Human Brain Work? - Caltech Science Exchange
Explore the intricate workings of the human brain, from neurons and glia to the central and peripheral nervous systems. Learn how sensory input, emotions, and memories shape our …
