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cohort study relative risk: Smart Health Choices Les Irwig, 2008 Every day we make decisions about our health - some big and some small. What we eat, how we live and even where we live can affect our health. But how can we be sure that the advice we are given about these important matters is right for us? This book will provide you with the right tools for assessing health advice. |
cohort study relative risk: Epidemiology and Biostatistics Bryan Kestenbaum, 2018-10-12 This workbook is designed to teach the major fundamental concepts in Epidemiology, Biostatistics, and clinical research design alongside the textbook Epidemiology and Biostatistics, 2nd Edition. It is written in concise and organized fashion with many examples to illustrate the concepts deriving from a collection of written materials created to teach Epidemiology and Biostatistics to medical students. The major differences from related titles include a “story” based approach toward teaching the material, relative brevity while maintaining focus on key concepts, and taking the perspective of first-time learners (avoiding and/or clearly defining jargon, using clear common-sense language). It features a variety of questions: long, short, and multiple choice questions. The workbook is made to provide students with the tools necessary to form their own informed conclusions from the clinical research literature. |
cohort study relative risk: Foundations of Epidemiology Marit L. Bovbjerg, 2020-10 Foundations of Epidemiology is an open access, introductory epidemiology text intended for students and practitioners in public or allied health fields. It covers epidemiologic thinking, causality, incidence and prevalence, public health surveillance, epidemiologic study designs and why we care about which one is used, measures of association, random error and bias, confounding and effect modification, and screening. Concepts are illustrated with numerous examples drawn from contemporary and historical public health issues. |
cohort study relative risk: Modern Epidemiology Kenneth J. Rothman, Sander Greenland, Timothy L. Lash, 2008 The thoroughly revised and updated Third Edition of the acclaimed Modern Epidemiology reflects both the conceptual development of this evolving science and the increasingly focal role that epidemiology plays in dealing with public health and medical problems. Coauthored by three leading epidemiologists, with sixteen additional contributors, this Third Edition is the most comprehensive and cohesive text on the principles and methods of epidemiologic research. The book covers a broad range of concepts and methods, such as basic measures of disease frequency and associations, study design, field methods, threats to validity, and assessing precision. It also covers advanced topics in data analysis such as Bayesian analysis, bias analysis, and hierarchical regression. Chapters examine specific areas of research such as disease surveillance, ecologic studies, social epidemiology, infectious disease epidemiology, genetic and molecular epidemiology, nutritional epidemiology, environmental epidemiology, reproductive epidemiology, and clinical epidemiology. |
cohort study relative risk: Applications of Regression Models in Epidemiology Erick Suárez, Cynthia M. Pérez, Roberto Rivera, Melissa N. Martínez, 2017-02-28 A one-stop guide for public health students and practitioners learning the applications of classical regression models in epidemiology This book is written for public health professionals and students interested in applying regression models in the field of epidemiology. The academic material is usually covered in public health courses including (i) Applied Regression Analysis, (ii) Advanced Epidemiology, and (iii) Statistical Computing. The book is composed of 13 chapters, including an introduction chapter that covers basic concepts of statistics and probability. Among the topics covered are linear regression model, polynomial regression model, weighted least squares, methods for selecting the best regression equation, and generalized linear models and their applications to different epidemiological study designs. An example is provided in each chapter that applies the theoretical aspects presented in that chapter. In addition, exercises are included and the final chapter is devoted to the solutions of these academic exercises with answers in all of the major statistical software packages, including STATA, SAS, SPSS, and R. It is assumed that readers of this book have a basic course in biostatistics, epidemiology, and introductory calculus. The book will be of interest to anyone looking to understand the statistical fundamentals to support quantitative research in public health. In addition, this book: • Is based on the authors’ course notes from 20 years teaching regression modeling in public health courses • Provides exercises at the end of each chapter • Contains a solutions chapter with answers in STATA, SAS, SPSS, and R • Provides real-world public health applications of the theoretical aspects contained in the chapters Applications of Regression Models in Epidemiology is a reference for graduate students in public health and public health practitioners. ERICK SUÁREZ is a Professor of the Department of Biostatistics and Epidemiology at the University of Puerto Rico School of Public Health. He received a Ph.D. degree in Medical Statistics from the London School of Hygiene and Tropical Medicine. He has 29 years of experience teaching biostatistics. CYNTHIA M. PÉREZ is a Professor of the Department of Biostatistics and Epidemiology at the University of Puerto Rico School of Public Health. She received an M.S. degree in Statistics and a Ph.D. degree in Epidemiology from Purdue University. She has 22 years of experience teaching epidemiology and biostatistics. ROBERTO RIVERA is an Associate Professor at the College of Business at the University of Puerto Rico at Mayaguez. He received a Ph.D. degree in Statistics from the University of California in Santa Barbara. He has more than five years of experience teaching statistics courses at the undergraduate and graduate levels. MELISSA N. MARTÍNEZ is an Account Supervisor at Havas Media International. She holds an MPH in Biostatistics from the University of Puerto Rico and an MSBA from the National University in San Diego, California. For the past seven years, she has been performing analyses for the biomedical research and media advertising fields. |
cohort study relative risk: Cochrane Handbook for Systematic Reviews of Interventions Julian P. T. Higgins, Sally Green, 2008-11-24 Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves. |
cohort study relative risk: Health Risks from Exposure to Low Levels of Ionizing Radiation Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation, National Research Council, 2006-03-23 This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation. |
cohort study relative risk: Practical Psychiatric Epidemiology Jayati Das-Munshi, Tamsin Ford, Matthew Hotopf, Martin Prince, Robert Stewart, 2020-02-13 Looking to the future of the ever-evolving field of psychiatric epidemiology, this new edition covers the many advances in the field since the release of the first. With new content on key topics from bioethics to life course epidemiology, this new edition will continue to be an invaluable reference for clinicians in practice and in training. |
cohort study relative risk: Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide Agency for Health Care Research and Quality (U.S.), 2013-02-21 This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov) |
cohort study relative risk: Epidemiology by Design Daniel Westreich, 2020 A (LONG OVERDUE) CAUSAL APPROACH TO INTRODUCTORY EPIDEMIOLOGY Epidemiology is recognized as the science of public health, evidence-based medicine, and comparative effectiveness research. Causal inference is the theoretical foundation underlying all of the above. No introduction to epidemiology is complete without extensive discussion of causal inference; what's missing is a textbook that takes such an approach. Epidemiology by Design takes a causal approach to the foundations of traditional introductory epidemiology. Through an organizing principle of study designs, it teaches epidemiology through modern causal inference approaches, including potential outcomes, counterfactuals, and causal identification conditions. Coverage in this textbook includes: � Introduction to measures of prevalence and incidence (survival curves, risks, rates, odds) and measures of contrast (differences, ratios); the fundamentals of causal inference; and principles of diagnostic testing, screening, and surveillance � Description of three key study designs through the lens of causal inference: randomized trials, prospective observational cohort studies, and case-control studies � Discussion of internal validity (within a sample), external validity, and population impact: the foundations of an epidemiologic approach to implementation science For first-year graduate students and advanced undergraduates in epidemiology and public health fields more broadly, Epidemiology by Design offers a rigorous foundation in epidemiologic methods and an introduction to methods and thinking in causal inference. This new textbook will serve as a foundation not just for further study of the field, but as a head start on where the field is going. |
cohort study relative risk: Critical Appraisal of Epidemiological Studies and Clinical Trials Mark Elwood, 2007-02-22 This book presents a logical system of critical appraisal, to allow readers to evaluate studies and to carry out their own studies more effectively. This system emphasizes the central importance of cause and effect relationships. Its great strength is that it is applicable to a wide range of issues, and both to intervention trials and observational studies. This system unifies the often different approaches used in epidemiology, health services research, clinical trials, and evidence-based medicine, starting from a logical consideration of cause and effect. The author's approach to the issues of study design, selection of subjects, bias, confounding, and the place of statistical methods has been praised for its clarity and interest. Systematic reviews, meta-analysis, and the applications of this logic to evidence-based medicine, knowledge-based health care, and health practice and policy are discussed. Current and often controversial examples are used, including screening for prostate cancer, publication bias in psychiatry, public health issues in developing countries, and conflicts between observational studies and randomized trials. Statistical issues are explained clearly without complex mathematics, and the most useful methods are summarized in the appendix. The final chapters give six applications of the critical appraisal of major studies: randomized trials of medical treatment and prevention, a prospective and a retrospective cohort study, a small matched case-control study, and a large case-control study. In these chapters, sections of the original papers are reproduced and the original studies placed in context by a summary of current developments. |
cohort study relative risk: Epidemiologic Research David G. Kleinbaum, Lawrence L. Kupper, Hal Morgenstern, 1991-01-16 Epidemiologic Research Principles and Quantitative Methods DavidG. Kleinbaum, Ph.D. Lawrence L. Kupper. Ph.D. Hal Morgenstern,Ph.D. Epidemiologic Research covers the principles and methodsof planning, analysis and interpretation of epidemiologic researchstudies. It supplies the applied researcher with the mostup-to-date methodological thought and practice. Specifically, thebook focuses on quantitative (including statistical) issues arisingfrom epidemiologic investigations, as well as on the questions ofstudy design, measurement and validity. EpidemiologicResearch emphasizes practical techniques, procedures andstrategies. It presents them through a unified approach whichfollows the chronology of issues that arise during theinvestigation of an epidemic. The book's viewpoint ismultidisciplinary and equally useful to the epidemiologicresearcher and to the biostatistician. Theory is supplemented bynumerous examples, exercises and applications. Full solutions aregiven to all exercises in a separate solutions manual. Importantfeatures * Thorough discussion of the methodology of epidemiologicresearch * Stress on validity and hence on reliability * Balanced approach, presenting the most important prevailingviewpoints * Three chapters with applications of mathematical modeling |
cohort study relative risk: Cohort Studies in Health Sciences R. Mauricio Barría, 2018 Introductory Chapter: The Contribution of Cohort Studies to Health Sciences. |
cohort study relative risk: Comparative Quantification of Health Risks: Sexual and reproductive health Majid Ezzati, 2004 Provides a comprehensive assessment of the scientific evidence on prevalence and the resulting health effects of a range of exposures that are know to be hazardous to human health, including childhood and maternal undernutrition, nutritional and physiological risk factors for adult health, addictive substances, sexual and reproductive health risks, and risks in the physical environments of households and communities, as well as among workers. This book is the culmination of over four years of scientific equiry and data collection, know as the comparative risk assessment (CRA) project. |
cohort study relative risk: Analysis of Cancer Risks in Populations Near Nuclear Facilities National Research Council, Division on Earth and Life Studies, Nuclear and Radiation Studies Board, Committee on the Analysis of Cancer Risks in Populations near Nuclear Facilitiesâ¬"Phase I, 2012-06-29 In the late 1980s, the National Cancer Institute initiated an investigation of cancer risks in populations near 52 commercial nuclear power plants and 10 Department of Energy nuclear facilities (including research and nuclear weapons production facilities and one reprocessing plant) in the United States. The results of the NCI investigation were used a primary resource for communicating with the public about the cancer risks near the nuclear facilities. However, this study is now over 20 years old. The U.S. Nuclear Regulatory Commission requested that the National Academy of Sciences provide an updated assessment of cancer risks in populations near USNRC-licensed nuclear facilities that utilize or process uranium for the production of electricity. Analysis of Cancer Risks in Populations near Nuclear Facilities: Phase 1 focuses on identifying scientifically sound approaches for carrying out an assessment of cancer risks associated with living near a nuclear facility, judgments about the strengths and weaknesses of various statistical power, ability to assess potential confounding factors, possible biases, and required effort. The results from this Phase 1 study will be used to inform the design of cancer risk assessment, which will be carried out in Phase 2. This report is beneficial for the general public, communities near nuclear facilities, stakeholders, healthcare providers, policy makers, state and local officials, community leaders, and the media. |
cohort study relative risk: Applying Quantitative Bias Analysis to Epidemiologic Data Timothy L. Lash, Matthew P. Fox, Aliza K. Fink, 2011-04-14 Bias analysis quantifies the influence of systematic error on an epidemiology study’s estimate of association. The fundamental methods of bias analysis in epi- miology have been well described for decades, yet are seldom applied in published presentations of epidemiologic research. More recent advances in bias analysis, such as probabilistic bias analysis, appear even more rarely. We suspect that there are both supply-side and demand-side explanations for the scarcity of bias analysis. On the demand side, journal reviewers and editors seldom request that authors address systematic error aside from listing them as limitations of their particular study. This listing is often accompanied by explanations for why the limitations should not pose much concern. On the supply side, methods for bias analysis receive little attention in most epidemiology curriculums, are often scattered throughout textbooks or absent from them altogether, and cannot be implemented easily using standard statistical computing software. Our objective in this text is to reduce these supply-side barriers, with the hope that demand for quantitative bias analysis will follow. |
cohort study relative risk: A Pocket Guide to Epidemiology David G. Kleinbaum, Kevin M. Sullivan, Nancy D. Barker, 2007-03-11 In the nearly three years since the publication of the ActivEpi companion text, the authors received several suggestions to produce an abbreviated version that narrows the discussion to the most essential principals and methods. A Pocket Guide to Epidemiology contains less than half as many pages as the ActivEpi Companion Text and is a stand-alone introductory text on the basic principals and concepts of epidemiology. |
cohort study relative risk: Epidemiology Kept Simple B. Burt Gerstman, 2013-05-17 Arranged to facilitate use and highlight key concepts, this clear and concise text also includes many practical exercises, case studies, and real-world applications. Utilizing the modern biostatistical approach to studying disease, Epidemiology Kept Simple, Second Edition will provide readers with the tools to interpret epidemiological data, understand disease concepts, and prepare for board exams. The author fully explains all new terminology and minimizes the use of technical language, while emphasizing real-life practice in modern public health and biomedical research settings. |
cohort study relative risk: Public Health Research Methods Greg Guest, Emily E. Namey, 2015 Providing a comprehensive foundation for planning, executing, and monitoring public health research of all types, this book goes beyond traditional epidemiologic research designs to cover technology-based approaches emerging in the new public health landscape. |
cohort study relative risk: Epidemiology in Medicine Julie E. Buring, 1987 Harvard Medical School, Boston. Textbook for medical and public health students. |
cohort study relative risk: Handbook of Hazardous Materials , 2012-12-02 Handbook of Hazardous Materials is a one-volume compendium of hazardous materials that discusses the toxic effects of these materials on human health and the global environment. It provides comprehensive coverage of individual toxic elements, covers hazardous material groups, and includes more general articles such as evaluation and testing of carcinogens, transport of pollutants, and inhalation toxicology. The fully referenced articles are presented in alphabetical order. The book features a subject index as well as numerous cross-references.Individual articles are preceded by a topical outline and discuss the origin, prevalence, mechanisms of toxicity and damaging effects of each hazardous material.Comprehensive coverage of individual toxic elements, includingAsbestosAlarLeadMercuryCoverage of hazardous material groups, such asPesticidesFood additivesNitrogen compoundsMore general articles, such asEvaluation and testing of carcinogensTransport of pollutantsInhalation toxicology |
cohort study relative risk: Health Effects of Exposure to Low Levels of Ionizing Radiation National Research Council, Division on Earth and Life Studies, Commission on Life Sciences, Committee on the Biological Effects of Ionizing Radiation (BEIR V), 1990-02-01 This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations. |
cohort study relative risk: Diarrhoea and Malnutrition in Childhood J.A. Walker-Smith, A. S. McNeish, 2013-10-22 Diarrhoea and Malnutrition in Childhood is derived from a conference of pediatric gastroenterologists from around the world, held in London at the Royal Commonwealth Society and St. Bartholomew's Hospital on November 5-7, 1984. They collaborate to create a source that would educate people from developed and developing communities regarding the topic. The book first tackles the connections between diarrhea and malnutrition, and then provides a model that further explains the relationship. The authors suggest that poverty is the main cause of the two abnormal conditions, and they refer to books and studies of the topic by respected figures in the industry. Bacteria that cause the two diseases and the diseases' variations are also covered. Other topics discussed in the book are parasites in the intestine; schemes on how to improve nutrition; importance of breast-feeding; and role that the parts of the human body play during illness. This book will serve as a valuable reference for doctors, researchers, and even casual readers. |
cohort study relative risk: Modern Statistical Methods in Chronic Disease Epidemiology Suresh H. Moolgavkar, Ross L. Prentice, 1986-05-09 Proceedings of a conference sponsored by the SIAM Institute for Mathematics and Society, and supported by the Department of Energy. Brings together recent developments in the statistical methodology for chronic disease epidimiology. The contributors are all at the forefront of biostatistics research. |
cohort study relative risk: Applied Regression Analysis and Other Multivariable Methods David G. Kleinbaum, Keith E.. Muller, Lawrence L. Kupper, 2008 This bestseller will help you learn regression-analysis methods that you can apply to real-life problems. It highlights the role of the computer in contemporary statistics with numerous printouts and exercises that you can solve using the computer. The authors continue to emphasize model development, the intuitive logic and assumptions that underlie the techniques covered, the purposes, advantages, and disadvantages of the techniques, and valid interpretations of those techniques. |
cohort study relative risk: Measures of Association for Cross Classifications L. A. Goodman, W. H. Kruskal, 2012-12-06 In 1954, prior to the era of modem high speed computers, Leo A. Goodman and William H. Kruskal published the fmt of a series of four landmark papers on measures of association for cross classifications. By describing each of several cross classifications using one or more interpretable measures, they aimed to guide other investigators in the use of sensible data summaries. Because of their clarity of exposition, and their thoughtful statistical approach to such a complex problem, the guidance in this paper is as useful and important today as it was on its publication 25 years ago. in a cross-classification by a single number inevita Summarizing association bly loses information. Only by the thoughtful choice of a measure of association can one hope to lose only the less important information and thus arrive at a satisfactory data summary. The series of four papers reprinted here serve as an outstanding guide to the choice of such measures and their use. |
cohort study relative risk: Saving Women's Lives National Research Council, Institute of Medicine, Policy and Global Affairs, Board on Science, Technology, and Economic Policy, National Cancer Policy Board, Committee on New Approaches to Early Detection and Diagnosis of Breast Cancer, 2005-03-18 The outlook for women with breast cancer has improved in recent years. Due to the combination of improved treatments and the benefits of mammography screening, breast cancer mortality has decreased steadily since 1989. Yet breast cancer remains a major problem, second only to lung cancer as a leading cause of death from cancer for women. To date, no means to prevent breast cancer has been discovered and experience has shown that treatments are most effective when a cancer is detected early, before it has spread to other tissues. These two facts suggest that the most effective way to continue reducing the death toll from breast cancer is improved early detection and diagnosis. Building on the 2001 report Mammography and Beyond, this new book not only examines ways to improve implementation and use of new and current breast cancer detection technologies but also evaluates the need to develop tools that identify women who would benefit most from early detection screening. Saving Women's Lives: Strategies for Improving Breast Cancer Detection and Diagnosis encourages more research that integrates the development, validation, and analysis of the types of technologies in clinical practice that promote improved risk identification techniques. In this way, methods and technologies that improve detection and diagnosis can be more effectively developed and implemented. |
cohort study relative risk: Evidence-Based Statistics Peter M. B. Cahusac, 2020-10-13 Evidence-Based Statistics: An Introduction to the Evidential Approach – from Likelihood Principle to Statistical Practice provides readers with a comprehensive and thorough guide to the evidential approach in statistics. The approach uses likelihood ratios, rather than the probabilities used by other statistical inference approaches. The evidential approach is conceptually easier to grasp, and the calculations more straightforward to perform. This book explains how to express data in terms of the strength of statistical evidence for competing hypotheses. The evidential approach is currently underused, despite its mathematical precision and statistical validity. Evidence-Based Statistics is an accessible and practical text filled with examples, illustrations and exercises. Additionally, the companion website complements and expands on the information contained in the book. While the evidential approach is unlikely to replace probability-based methods of statistical inference, it provides a useful addition to any statistician’s “bag of tricks.” In this book: It explains how to calculate statistical evidence for commonly used analyses, in a step-by-step fashion Analyses include: t tests, ANOVA (one-way, factorial, between- and within-participants, mixed), categorical analyses (binomial, Poisson, McNemar, rate ratio, odds ratio, data that’s ‘too good to be true’, multi-way tables), correlation, regression and nonparametric analyses (one sample, related samples, independent samples, multiple independent samples, permutation and bootstraps) Equations are given for all analyses, and R statistical code provided for many of the analyses Sample size calculations for evidential probabilities of misleading and weak evidence are explained Useful techniques, like Matthews’s critical prior interval, Goodman’s Bayes factor, and Armitage’s stopping rule are described Recommended for undergraduate and graduate students in any field that relies heavily on statistical analysis, as well as active researchers and professionals in those fields, Evidence-Based Statistics: An Introduction to the Evidential Approach – from Likelihood Principle to Statistical Practice belongs on the bookshelf of anyone who wants to amplify and empower their approach to statistical analysis. |
cohort study relative risk: Epidemiology Mark Woodward, 1999-05-25 Epidemiology is a subject of growing importance, as witnessed by its role in the description and prediction of the impact of new diseases such as AIDS and new-variant CJD. Epidemiology: Study Design and Data Analysis covers the whole spectrum of standard analytical techniques used in epidemiology, from descriptive techniques in report writing to model diagnostics from generalized linear models. The author discusses the advantages, disadvantages, and alternatives to case-control, cohort and intervention studies and details such crucial concepts as incidence, prevalence, confounding and interaction. Many exercises are provided, based on real epidemiological data sets collected from all over the world. The data sets are also available on an associated web site. Epidemiology: Study Design and Data Analysis will be an invaluable textbook for statistics and medical students studying epidemiology, and a standard reference for practicing epidemiologists. |
cohort study relative risk: The Health Consequences of Involuntary Exposure to Tobacco Smoke , 2006 This Surgeon General's report returns to the topic of the health effects of involuntary exposure to tobacco smoke. The last comprehensive review of this evidence by the Department of Health and Human Services (DHHS) was in the 1986 Surgeon General's report, The Health Consequences of Involuntary Smoking, published 20 years ago this year. This new report updates the evidence of the harmful effects of involuntary exposure to tobacco smoke. This large body of research findings is captured in an accompanying dynamic database that profiles key epidemiologic findings, and allows the evidence on health effects of exposure to tobacco smoke to be synthesized and updated (following the format of the 2004 report, The Health Consequences of Smoking). The database enables users to explore the data and studies supporting the conclusions in the report. The database is available on the Web site of the Centers for Disease Control and Prevention (CDC) at http://www.cdc.gov/tobacco. |
cohort study relative risk: Research in Medical and Biological Sciences Petter Laake, Haakon Breien Benestad, Bjorn R. Olsen, 2015-06-05 Research in Medical and Biological Sciences covers the wide range of topics that a researcher must be familiar with in order to become a successful biomedical scientist. Perfect for aspiring as well as practicing professionals in the medical and biological sciences, this publication discusses a broad range of topics that are common yet not traditionally considered part of formal curricula, including philosophy of science, ethics, statistics, and grant applications. The information presented in this book also facilitates communication across conventional disciplinary boundaries, in line with the increasingly multidisciplinary nature of modern research projects. - Covers the breadth of topics that a researcher must understand in order to be a successful experimental scientist - Provides a broad scientific perspective that is perfect for students with various professional backgrounds - Contains easily accessible, concise material about diverse methods - Includes extensive online resources such as further reading suggestions, data files, statistical tables, and the StaTable application package - Emphasizes the ethics and statistics of medical and biological sciences |
cohort study relative risk: The Future of the Public's Health in the 21st Century Institute of Medicine, Board on Health Promotion and Disease Prevention, Committee on Assuring the Health of the Public in the 21st Century, 2003-02-01 The anthrax incidents following the 9/11 terrorist attacks put the spotlight on the nation's public health agencies, placing it under an unprecedented scrutiny that added new dimensions to the complex issues considered in this report. The Future of the Public's Health in the 21st Century reaffirms the vision of Healthy People 2010, and outlines a systems approach to assuring the nation's health in practice, research, and policy. This approach focuses on joining the unique resources and perspectives of diverse sectors and entities and challenges these groups to work in a concerted, strategic way to promote and protect the public's health. Focusing on diverse partnerships as the framework for public health, the book discusses: The need for a shift from an individual to a population-based approach in practice, research, policy, and community engagement. The status of the governmental public health infrastructure and what needs to be improved, including its interface with the health care delivery system. The roles nongovernment actors, such as academia, business, local communities and the media can play in creating a healthy nation. Providing an accessible analysis, this book will be important to public health policy-makers and practitioners, business and community leaders, health advocates, educators and journalists. |
cohort study relative risk: Handbook for Clinical Research Flora Hammond, MD, James F. Malec, Todd Nick, Ralph Buschbacher, MD, 2014-08-26 With over 80 information-packed chapters, Handbook for Clinical Research delivers the practical insights and expert tips necessary for successful research design, analysis, and implementation. Using clear language and an accessible bullet point format, the authors present the knowledge and expertise developed over time and traditionally shared from mentor to mentee and colleague to colleague. Organized for quick access to key topics and replete with practical examples, the book describes a variety of research designs and statistical methods and explains how to choose the best design for a particular project. Research implementation, including regulatory issues and grant writing, is also covered. The book opens with a section on the basics of research design, discussing the many ways in which studies can be organized, executed, and evaluated. The second section is devoted to statistics and explains how to choose the correct statistical approach and reviews the varieties of data types, descriptive and inferential statistics, methods for demonstrating associations, hypothesis testing and prediction, specialized methods, and considerations in epidemiological studies and measure construction. The third section covers implementation, including how to develop a grant application step by step, the project budget, and the nuts and bolts of the timely and successful completion of a research project and documentation of findings: procedural manuals and case report forms collecting, managing and securing data operational structure and ongoing monitoring and evaluation and ethical and regulatory concerns in research with human subjects. With a concise presentation of the essentials for successful research, the Handbook for Clinical Research is a valuable addition to the library of any student, research professional, or clinician interested in expanding the knowledge base of his or her field. Key Features: Delivers the essential elements, practical insights, and trade secrets for ensuring successful research design, analysis, and implementation Presents the nuts and bolts of statistical analysis Organized for quick access to a wealth of information Replete with practical examples of successful research designs Û from single case designs to meta-analysis - and how to achieve them Addresses research implementation including regulatory issues and grant writing |
cohort study relative risk: Generalized Linear Models and Extensions, Second Edition James W. Hardin, James William Hardin, Joseph M. Hilbe, Joseph Hilbe, 2007 Deftly balancing theory and application, this book stands out in its coverage of the derivation of the GLM families and their foremost links. This edition has new sections on discrete response models, including zero-truncated, zero-inflated, censored, and hurdle count models, as well as heterogeneous negative binomial, and more. |
cohort study relative risk: Epidemiologic Studies of Veterans Exposed to Depleted Uranium Institute of Medicine, Board on Population Health and Public Health Practice, Committee on Gulf War and Health: Updated Literature Review of Depleted Uranium, 2008-09-11 Depleted uranium, a component of some weapons systems, has been in use by the U.S. military since the 1991 Gulf War. Military personnel have been exposed to depleted uranium as the result of friendly fire incidents, cleanup and salvage operations, and proximity to burning depleted uranium-containing tanks and ammunition. Under a Congressional mandate, the Department of Defense sought guidance from the Institute of Medicine in evaluating the feasibility and design of an epidemiologic study that would assess health outcomes of exposure to depleted uranium. The study committee examined several options to study health outcomes of depleted uranium exposure in military and veteran populations and concluded that it would be difficult to design a study to comprehensively assess depleted uranium-related health outcomes with currently available data. The committee further concluded that the option most likely to obtain useful information about depleted uranium-related health outcomes would be a prospective cohort study if future military operations involve exposure to depleted uranium. The book contains recommendations aimed at improving future epidemiologic studies and identifying current active-duty military personnel and veterans with potential DU exposure. |
cohort study relative risk: Encyclopedia of Behavioral Medicine Marc D. Gellman, J. Rick Turner, |
cohort study relative risk: Epidemiology Moyses Szklo, F. Javier Nieto, 2014 This book is specifically designed to expand reader knowledge while avoiding complex statistical formulations. Emphasizing the quantitative issues of epidemiology, this book focuses on study design, measures of association, interaction, research assessment, and other methods and practice. The Second Edition takes readers who have a good understanding of basic epidemiological principles through more rigorous discussions of concepts and methods. |
cohort study relative risk: Clinical Trials in Neurology Roberto J. Guiloff, 2013-03-14 Clinical Trials in Neurology comprehensively tackles the methodology and design of clinical trials in neurological disease. A general section deals with the ethical aspects, drug development and regulatory requirements, basic trial designs and the statistics used. A diseases section tackles specific aspects of disorders, focusing on the relevant ethical issues, outcome variables and experience with large multicentre trials. |
cohort study relative risk: Prevention of Myocardial Infarction JoAnn E. Manson, 1996 Coronary heart disease remains the leading cause of death in both men and women in most industrialized countries. Yet it is largely preventable, and health care providers can acquire the skills to help their patients reduce their risks substantially. Traditional risk factors such as cigarette smoking, hypercholesterolimia, hypertension, sedentary lifestyle, obesity and glucose intolerance explain a major proportion of coronary events. Recent evidence also suggests important adjunctive roles for hormone replacement therapy in postmenopausal women, and aspirin prophlaxis in individuals at high risk of a first myocardial infarction. Emerging evidence indicates an important role for diet in the prevention of heart disease. Although the importance of lifestyle and behavioral modifications may well be known among physicians and other health-care providers, the implementation of this knowledge has been limited. One reason is that the information supporting the value, feasibility and cost-effectiveness of risk-reduction strategies has not been previously synthesized and made widely available to health-care providers in office and community settings. Prevention of Myocardial Infarction fills these critical gaps by providing a state-of-the-art compendium of the scientific evidence on the efficacy of coronary disease prevention, while focusing on helping clinicians develop intervention skills to utilize available knowledge. Chapters by leading authorities in cardiovascular epidemiology, clinical cardiology, cost-effectiveness analysis, and public health translate the theory of preventive cardiology into feasible implementation. The counseling and other intervention strategies described in this textbook have documented clinical efficacy and cost-effectiveness, and they require little time to learn or implement. The book is written mainly for primary care providers, including general internists and family physicians, but will also be of interest to medical subspecialties such as cardiologists and endocrinologists, as well as medical students, dietitians, psychologists, epidemiologists, and students, practitioners, and researchers in public health. |
cohort study relative risk: The Analysis of Case-control Studies Norman E. Breslow, N. E. Day, 1980 |
COHORT Definition & Meaning - Merriam-Webster
In ancient times, a cohort was a military unit, one of ten divisions in a Roman legion. The term passed into English in the 15th century, when it was used in translations and writings about …
COHORT | English meaning - Cambridge Dictionary
COHORT definition: 1. a group of people who share a characteristic, usually age: 2. a group of people who support a…. Learn more.
Cohort - Wikipedia
Cohort (military unit), the basic tactical unit of a Roman legion; Cohort (educational group), a group of students working together through the same academic curriculum
Cohort - Definition, Meaning & Synonyms - Vocabulary.com
A cohort is a group of people who are around the same age, like a cohort of college students who have similar experiences and concerns. The word cohort was originally used to describe a …
COHORT definition and meaning | Collins English Dictionary
A cohort of people is a group who have something in common. Cohort is used especially when a group is being looked at as a whole for statistical purposes. Tests were carried out on the …
Cohort: Definition, Meaning, and Examples - usdictionary.com
Jan 29, 2025 · "Cohort" Definition: What Does "Cohort" Mean? The term "cohort" encompasses several definitions, reflecting its evolution from ancient to contemporary contexts. Below, these …
cohort noun - Definition, pictures, pronunciation and usage notes ...
Definition of cohort noun in Oxford Advanced Learner's Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more.
COHORT Definition & Meaning | Dictionary.com
A cohort is a group of people, as in The senator is traveling with a large cohort. It can also refer to an associate or companion, as in I’m meeting up with some of my cohorts from my days as a …
Cohort - definition of cohort by The Free Dictionary
1. a companion, associate, or accomplice. 2. a group or company. 3. one of the ten divisions of a Roman legion.
COHORT | definition in the Cambridge English Dictionary
COHORT meaning: 1. a group of people who share a characteristic, usually age: 2. a group of people who support a…. Learn more.
COHORT Definition & Meaning - Merriam-Webster
In ancient times, a cohort was a military unit, one of ten divisions in a Roman legion. The term passed into English in the 15th century, when it was used in translations and writings about …
COHORT | English meaning - Cambridge Dictionary
COHORT definition: 1. a group of people who share a characteristic, usually age: 2. a group of people who support a…. Learn more.
Cohort - Wikipedia
Cohort (military unit), the basic tactical unit of a Roman legion; Cohort (educational group), a group of students working together through the same academic curriculum
Cohort - Definition, Meaning & Synonyms - Vocabulary.com
A cohort is a group of people who are around the same age, like a cohort of college students who have similar experiences and concerns. The word cohort was originally used to describe a …
COHORT definition and meaning | Collins English Dictionary
A cohort of people is a group who have something in common. Cohort is used especially when a group is being looked at as a whole for statistical purposes. Tests were carried out on the …
Cohort: Definition, Meaning, and Examples - usdictionary.com
Jan 29, 2025 · "Cohort" Definition: What Does "Cohort" Mean? The term "cohort" encompasses several definitions, reflecting its evolution from ancient to contemporary contexts. Below, these …
cohort noun - Definition, pictures, pronunciation and usage notes ...
Definition of cohort noun in Oxford Advanced Learner's Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more.
COHORT Definition & Meaning | Dictionary.com
A cohort is a group of people, as in The senator is traveling with a large cohort. It can also refer to an associate or companion, as in I’m meeting up with some of my cohorts from my days as a …
Cohort - definition of cohort by The Free Dictionary
1. a companion, associate, or accomplice. 2. a group or company. 3. one of the ten divisions of a Roman legion.
COHORT | definition in the Cambridge English Dictionary
COHORT meaning: 1. a group of people who share a characteristic, usually age: 2. a group of people who support a…. Learn more.