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| brown laboratory of chemistry purdue: The Road to Stockholm István Hargittai, 2002 The Nobel Prize is by far the highest recognition a scientist may receive and the only one with which the general public is familiar. Its prestige has reached improbable heights. At the same time a lot of myth surrounds the Nobel Prize, and this is compounded by the fact that people tend to view scientists with some bewilderment. This book introduces the process of selection of the laureates, discusses the ingredients for scientific discovery and for getting recognition. It reviews the decisive moments of scientific careers en route to the Nobel Prize, points to characteristic features of the laureates, the importance of mentors and venues in scientific careers and other components of success. It also covers some discoverers and discoveries for whom and for which the Nobel Prize never materialized. Whereas there is no general recipe for receiving the Nobel Prize, there are common features of successful scientific careers. The book reveals some information about the scientists' lives and careers that may guide other scientists in increasing their chances of becoming more effective and better recognized players--although it is not expected to help anyone to receive the Nobel Prize! For the general reader The Road to Stockholm reveals the human face of scientists and the human side of their endeavours. The Nobel Prize has served as inspiration for scientists and the general public for a hundred years: this book discusses its problems and celebrates its triumphs. |
| brown laboratory of chemistry purdue: Hydrides of Boron and Silicon Alfred Stock, 1957 |
| brown laboratory of chemistry purdue: Candid Science: Conversations With Famous Chemists Istvan Hargittai, 2000-01-26 In this book, 36 famous chemists, including 18 Nobel laureates, tell about their lives in science, the beginnings of their careers, their aspirations, and their hardships and triumphs. The reader will learn about their seminal discoveries, and the conversations in the book bring out the humanity of these great scientists. NMR spectroscopy, computational chemistry, the drama of buckminsterfullerene, the story of the Pill, the politics of atmospheric chemistry and the resonance theory, the beginnings of molecular mechanics and modern stereochemistry are examples of the topics discussed first-hand by, in all likelihood, the most appropriate persons. |
| brown laboratory of chemistry purdue: The Organic Chem Lab Survival Manual James W. Zubrick, 2020-02-05 Teaches students the basic techniques and equipment of the organic chemistry lab — the updated new edition of the popular hands-on guide. The Organic Chem Lab Survival Manual helps students understand the basic techniques, essential safety protocols, and the standard instrumentation necessary for success in the laboratory. Author James W. Zubrick has been assisting students navigate organic chemistry labs for more than three decades, explaining how to set up the laboratory, make accurate measurements, and perform safe and meaningful experiments. This practical guide covers every essential area of lab knowledge, from keeping detailed notes and interpreting handbooks to using equipment for chromatography and infrared spectroscopy. Now in its eleventh edition, this guide has been thoroughly updated to cover current laboratory practices, instruments, and techniques. Focusing primarily on macroscale equipment and experiments, chapters cover microscale jointware, drying agents, recrystallization, distillation, nuclear magnetic resonance, and much more. This popular textbook: Familiarizes students with common lab instruments Provides guidance on basic lab skills and procedures Includes easy-to-follow diagrams and illustrations of lab experiments Features practical exercises and activities at the end of each chapter Provides real-world examples of lab notes and instrument manuals The Organic Chem Lab Survival Manual: A Student’s Guide to Techniques, 11th Edition is an essential resource for students new to the laboratory environment, as well as those more experienced seeking to refresh their knowledge. |
| brown laboratory of chemistry purdue: Nobel Laureates in Chemistry, 1901-1992 James K. Laylin, 1993-10-30 Through new perspectives from a mix of original monographs, biographies, autobiographical memoirs, edited collections of essays and documentary sources, translations, classic reprints, and pictorial volumes, this series will document the individuals, ideas, institutions, and innovations that have created the modern chemcial sciences. |
| brown laboratory of chemistry purdue: Great Minds Balazs Hargittai, Magdolna Hargittai, István Hargittai, 2014 A collection of interviews with 111 notable scientists, whose disciplines range from physics to chemistry to the biosciences, collected throughout the last 25 years. |
| brown laboratory of chemistry purdue: Applied Ethics in Animal Research John P. Gluck, Tony DiPasquale, F. Barbara Orlans, 2002 This volume is a collection of chapters all contributed by individuals who have presented their ideas at conferences and who take moderate stands with the use of animals in research. Specifically the chapters bear of the issues of: notions of the moral standings of animals, history of the methods of argumentation, knowledge of the animal mind, nature and value of regulatory structures, how respect for animals can be converted from theory to action in the laboratory. The chapters have been tempered by open discussion with individuals with different opinions and not audiences of true believers. It is the hope of all, that careful consideration of the positions in these chapters will leave reader with a deepened understanding--not necessarily a hardened position. |
| brown laboratory of chemistry purdue: Organometallic Ion Chemistry B.S. Freiser, 2012-12-06 A study covering the gas-phase chemistry of organometallic ions. Topics covered include: periodic trends in gas-phase thermochemistry of transition metal-ligand systems; ab initio calculations to determine electronic structure, geometric structure, and thermochemistry of metal-containing systems; electronic state effects on metal ion reactivity; organometallic ion photochemistry; and applications of gas-phase electron transfer equilibria in organometallic redox thermochemistry. Also included are state-of-the-art mass spectrometric instrumentation used in such studies. It also features a comprehensive list (containing over 1500 entries) of metal ion-ligand bond energies, obtained from theory and experiment. |
| brown laboratory of chemistry purdue: A University of Tradition Purdue Reamer Club, 2013 A University of Tradition is a fascinating compilation of history, customs, pictures, and facts about Purdue University from its founding in 1869 to the present day. Covering all aspects of Purdue, from the origin of the nickname of its students and alumni--Boilermakers--to a chronological list of all buildings ever constructed on the campus of West Lafayette, Indiana, this book presents the ultimate insider's guide to one of the world's great universities. It contains a wealth of facts about student, academic, sporting, and campus traditions, as well as biographical information on all the University presidents and other members of Purdue's family, including David Ross, Neil Armstrong, Eliza Fowler, Jack Mollenkopf, Helen Schleman, and Amelia Earhart. A University of Tradition spotlights many items that will spark the memories of any Purdue alumnus or fan. No matter if you were in the All-American Marching Band, lived in the Quad, participated in Grand Prix, wrote for the Purdue Exponent, or were on campus when the Boilermakers won the 1967 Rose Bowl, you will appreciate and enjoy this book. The second edition is fully updated for 2012 and includes information about new landmarks, new traditions, and the incoming twelfth president of the University. |
| brown laboratory of chemistry purdue: Handbook on the Physics and Chemistry of Rare Earths , 2018-11-17 Handbook on the Physics and Chemistry of Rare Earths: Including Actinides, Volume 54, is a continuous series of books covering all aspects of rare earth science, including chemistry, life sciences, materials science and physics. The book's main emphasis is on rare earth elements [Sc, Y, and the lanthanides (La through Lu], but whenever relevant, information is also included on the closely related actinide elements. Individual chapters are comprehensive, broad, up-to-date, critical reviews written by highly experienced, invited experts. The series, which was started in 1978 by Professor Karl A. Gschneidner Jr., combines, and integrates, both the fundamentals and applications of these elements. - Presents up-to-date overviews and new developments in the field of rare earths, covering both their physics and chemistry - Contains Individual chapters that are comprehensive and broad, along with critical reviews - Provides contributions from highly experienced, invited experts |
| brown laboratory of chemistry purdue: Teaching Engineering, Second Edition Phillip C. Wankat, Frank S. Oreovicz, 2015-01-15 The majority of professors have never had a formal course in education, and the most common method for learning how to teach is on-the-job training. This represents a challenge for disciplines with ever more complex subject matter, and a lost opportunity when new active learning approaches to education are yielding dramatic improvements in student learning and retention. This book aims to cover all aspects of teaching engineering and other technical subjects. It presents both practical matters and educational theories in a format useful for both new and experienced teachers. It is organized to start with specific, practical teaching applications and then leads to psychological and educational theories. The practical orientation section explains how to develop objectives and then use them to enhance student learning, and the theoretical orientation section discusses the theoretical basis for learning/teaching and its impact on students. Written mainly for PhD students and professors in all areas of engineering, the book may be used as a text for graduate-level classes and professional workshops or by professionals who wish to read it on their own. Although the focus is engineering education, most of this book will be useful to teachers in other disciplines. Teaching is a complex human activity, so it is impossible to develop a formula that guarantees it will be excellent. However, the methods in this book will help all professors become good teachers while spending less time preparing for the classroom. This is a new edition of the well-received volume published by McGraw-Hill in 1993. It includes an entirely revised section on the Accreditation Board for Engineering and Technology (ABET) and new sections on the characteristics of great teachers, different active learning methods, the application of technology in the classroom (from clickers to intelligent tutorial systems), and how people learn. |
| brown laboratory of chemistry purdue: Ambient Ionization Mass Spectrometry Marek Domin, Robert Cody, 2014-11-25 Ambient ionization has emerged as one of the hottest and fastest growing topics in mass spectrometry enabling sample analysis with minimal sample preparation. Introducing the subject and explaining the basic concepts and terminology, this book will provide a comprehensive, unique treatise devoted to the subject. Written by acknowledged experts, there are full descriptions on how new ionization techniques work, with an overview of their strengths, weaknesses and applications. This title will bring the reader right up to date, with both applications and theory, and will be suitable as a tutorial text for those starting in the field from a variety of disciplines. |
| brown laboratory of chemistry purdue: Organic Syntheses Via Boranes Herbert Charles Brown, 1975 |
| brown laboratory of chemistry purdue: The Poison Squad Deborah Blum, 2018-09-25 A New York Times Notable Book The inspiration for PBS's AMERICAN EXPERIENCE film The Poison Squad. From Pulitzer Prize winner and New York Times-bestselling author Deborah Blum, the dramatic true story of how food was made safe in the United States and the heroes, led by the inimitable Dr. Harvey Washington Wiley, who fought for change By the end of nineteenth century, food was dangerous. Lethal, even. Milk might contain formaldehyde, most often used to embalm corpses. Decaying meat was preserved with both salicylic acid, a pharmaceutical chemical, and borax, a compound first identified as a cleaning product. This was not by accident; food manufacturers had rushed to embrace the rise of industrial chemistry, and were knowingly selling harmful products. Unchecked by government regulation, basic safety, or even labelling requirements, they put profit before the health of their customers. By some estimates, in New York City alone, thousands of children were killed by embalmed milk every year. Citizens--activists, journalists, scientists, and women's groups--began agitating for change. But even as protective measures were enacted in Europe, American corporations blocked even modest regulations. Then, in 1883, Dr. Harvey Washington Wiley, a chemistry professor from Purdue University, was named chief chemist of the agriculture department, and the agency began methodically investigating food and drink fraud, even conducting shocking human tests on groups of young men who came to be known as, The Poison Squad. Over the next thirty years, a titanic struggle took place, with the courageous and fascinating Dr. Wiley campaigning indefatigably for food safety and consumer protection. Together with a gallant cast, including the muckraking reporter Upton Sinclair, whose fiction revealed the horrific truth about the Chicago stockyards; Fannie Farmer, then the most famous cookbook author in the country; and Henry J. Heinz, one of the few food producers who actively advocated for pure food, Dr. Wiley changed history. When the landmark 1906 Food and Drug Act was finally passed, it was known across the land, as Dr. Wiley's Law. Blum brings to life this timeless and hugely satisfying David and Goliath tale with righteous verve and style, driving home the moral imperative of confronting corporate greed and government corruption with a bracing clarity, which speaks resoundingly to the enormous social and political challenges we face today. |
| brown laboratory of chemistry purdue: Planetary Surface Processes H. Jay Melosh, 2011-08-25 Planetary Surface Processes is the first advanced textbook to cover the full range of geologic processes that shape the surfaces of planetary-scale bodies. Using a modern, quantitative approach, this book reconsiders geologic processes outside the traditional terrestrial context. It highlights processes that are contingent upon Earth's unique circumstances and processes that are universal. For example, it shows explicitly that equations predicting the velocity of a river are dependent on gravity: traditional geomorphology textbooks fail to take this into account. This textbook is a one-stop source of information on planetary surface processes, providing readers with the necessary background to interpret new data from NASA, ESA and other space missions. Based on a course taught by the author at the University of Arizona for 25 years, it is aimed at advanced students, and is also an invaluable resource for researchers, professional planetary scientists and space-mission engineers. |
| brown laboratory of chemistry purdue: Recent Advances In Molecular Spectroscopy Of Polyatomic Molecules And Small Clusters Koji Kaya, 1994 |
| brown laboratory of chemistry purdue: Solid-state Chemistry of Drugs Stephen R. Byrn, 1999 |
| brown laboratory of chemistry purdue: Optimization of Solid-Phase Combinatorial Synthesis Bing Yan, Anthony W. Czarnik, 2001-12-04 Addresses the key topic in combinatorial synthesis--how to optimize the quality of a combinatorial library--by determining the usefulness of synthesized compunds, the reliability of biological assay results, and analyzing acadmic and industrial applications, real-world examples, and case studies of successful and unsuccessful technologies. |
| brown laboratory of chemistry purdue: Nonlinear Optical Polarization Analysis in Chemistry and Biology Garth J. Simpson, 2017-03-24 Presents a clear systematic molecular-based description of nonlinear optical polarization analysis of chemical and biological assemblies. |
| brown laboratory of chemistry purdue: Environmental Catalysis Vicki H. Grassian, 2005-05-26 The study of environmental interfaces and environmental catalysis is central to finding more effective solutions to air pollution and in understanding of how pollution impacts the natural environment. Encompassing concepts, techniques, and methods, Environmental Catalysis provides a mix of theory, computation, analysis, and synthesis to support the |
| brown laboratory of chemistry purdue: Nanoscience Proceedings of the National Academy of Sciences, 2002 |
| brown laboratory of chemistry purdue: Combinatorial Chemistry Hicham Fenniri, 2000-10-05 Combinatorial Chemistry is a genuine practical guide covering all the major areas of combinatorial chemistry from an experimental and conceptual point of view. Being one of the most powerful of modern technologies, combinatorial chemistry has had implications to many areas of chemistry and biology and the current approaches to drug, catalyst, receptor, and materials development and discovery are all included in this volume. It also contains protocols on solid, liquid, and solution phase synthesis and expedient methods of library screening and evaluation. The use of automation and robotics is also explained. It is written at a level easily accessible to novices and will enable readers to use combinatorial techniques to the best advantage. |
| brown laboratory of chemistry purdue: Metal Catalyzed Cross-Coupling Reactions and More Armin de Meijere, Stefan Bräse, Martin Oestreich, 2013-12-04 This three volume book is the follow-up handbook to the bestselling volume Metal-Catalyzed Cross-Coupling Reactions, the definitive reference in the field. In line with the enormous developments in this area, this is not a new edition, but rather a new book in three volumes with over 50% more content. This new content includes C-H activation, shifting the focus away from typical cross-coupling reactions, while those topics and chapters found in de Meijere/Diederich's book have been updated and expanded. With its highly experienced editor team and the list of authors reading like an international Who's-Who in the field, this work will be of great interest to every synthetic chemist working in academia and industry. |
| brown laboratory of chemistry purdue: Comprehensive Organometallic Chemistry II Richard J. Puddephatt, Edward W. Abel, 1995 |
| brown laboratory of chemistry purdue: Handbook of Organopalladium Chemistry for Organic Synthesis Ei-ichi Negishi, Armin de Meijere, 2003-11-24 Organized to provide maximum utility to the bench synthetic chemist. The editor is well-known for his work in exploring, developing, and applying organopalladium chemistry. Contributors include over 24 world authorities in the field. |
| brown laboratory of chemistry purdue: Drug Discovery and Development - E-Book Raymond G Hill, 2012-07-20 The modern pharmacopeia has enormous power to alleviate disease, and owes its existence almost entirely to the work of the pharmaceutical industry. This book provides an introduction to the way the industry goes about the discovery and development of new drugs. The first part gives a brief historical account from its origins in the mediaeval apothecaries' trade, and discusses the changing understanding of what we mean by disease, and what therapy aims to achieve, as well as summarising case histories of the discovery and development of some important drugs. The second part focuses on the science and technology involved in the discovery process: the stages by which a promising new chemical entity is identified, from the starting point of a medical need and an idea for addressing it. A chapter on biopharmaceuticals, whose discovery and development tend to follow routes somewhat different from synthetic compounds, is included here, as well as accounts of patent issues that arise in the discovery phase, and a chapter on research management in this environment. The third section of the book deals with drug development: the work that has to be undertaken to turn the drug candidate that emerges from the discovery process into a product on the market. - The definitive introduction to how a pharmaceutical company goes about its business of discovering and developing drugs. The second edition has a new editor: Professor Raymond Hill ● non-executive director of Addex Pharmaceuticals, Covagen and of Orexo AB ● Visiting Industrial Professor of Pharmacology in the University of Bristol ● Visiting Professor in the School of Medical and Health Sciences at the University of Surrey ● Visiting Professor in Physiology and Pharmacology at the University of Strathclyde ● President and Chair of the Council of the British Pharmacological Society ● member of the Nuffield Council on Bioethics and the Advisory Council on Misuse of Drugs. New to this edition: - Completely rewritten chapter on The Role of Medicinal Chemistry in the Drug Discovery Process. - New topic - DMPK Optimization Strategy in drug discovery. - New chapter on Scaffolds: Small globular proteins as antibody substitutes. - Totally updated chapters on Intellectual Property and Marketing - 50 new illustrations in full colour Features - Accessible, general guide to pharmaceutical research and development. - Examines the interfaces between cost and social benefit, quality control and mass production, regulatory bodies, patent management, and all interdisciplinary intersections essential to effective drug development. - Written by a strong team of scientists with long experience in the pharmaceutical industry. - Solid overview of all the steps from lab bench to market in an easy-to-understand way which will be accessible to non-specialists. From customer reviews of the previous edition: '... it will have everything you need to know on this module. Deeply referenced and, thus, deeply reliable. - Highly Commended in the medicine category of the BMA 2006 medical book competition - Winner of the Royal Society of Medicine Library Prize for Medical Book of the Year |
| brown laboratory of chemistry purdue: Biological Pigments—Advances in Research and Application: 2012 Edition , 2012-12-26 Biological Pigments—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biological Pigments. The editors have built Biological Pigments—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biological Pigments in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Biological Pigments—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| brown laboratory of chemistry purdue: Pharmaceutical Crystals Tong Li, Alessandra Mattei, 2018-09-03 An important resource that puts the focus on understanding and handling of organic crystals in drug development Since a majority of pharmaceutical solid-state materials are organic crystals, their handling and processing are critical aspects of drug development. Pharmaceutical Crystals: Science and Engineering offers an introduction to and thorough coverage of organic crystals, and explores the essential role they play in drug development and manufacturing. Written contributions from leading researchers and practitioners in the field, this vital resource provides the fundamental knowledge and explains the connection between pharmaceutically relevant properties and the structure of a crystal. Comprehensive in scope, the text covers a range of topics including: crystallization, molecular interactions, polymorphism, analytical methods, processing, and chemical stability. The authors clearly show how to find solutions for pharmaceutical form selection and crystallization processes. Designed to be an accessible guide, this book represents a valuable resource for improving the drug development process of small drug molecules. This important text: Includes the most important aspects of solid-state organic chemistry and its role in drug development Offers solutions for pharmaceutical form selection and crystallization processes Contains a balance between the scientific fundamental and pharmaceutical applications Presents coverage of crystallography, molecular interactions, polymorphism, analytical methods, processing, and chemical stability Written for both practicing pharmaceutical scientists, engineers, and senior undergraduate and graduate students studying pharmaceutical solid-state materials, Pharmaceutical Crystals: Science and Engineering is a reference and textbook for understanding, producing, analyzing, and designing organic crystals which is an imperative skill to master for anyone working in the field. |
| brown laboratory of chemistry purdue: A History of Modern Chemistry Noboru Hirota, 2016 This publication is a translation of the book entitles Gendai Kagakusi (A History of Modern Chemistry) published by Kyoto University Press in 2013. |
| brown laboratory of chemistry purdue: Women Succeeding in the Sciences Jody Bart, 2000 Ample evidence has been provided that women historically have suffered numerous social, political, and institutional barriers to their entrance and success in the sciences. The articles in this anthology refocus the discussion and reflect the interdisciplinary nature of the issues surrounding women in the sciences. While the barriers that women have faced as researchers, subjects of research, students of science, and theorists have been well documented, this anthology breaks new ground. It presents the ways women succeed in the sciences, overcome these historical barriers, and contribute to the social practice of science and the philosophy of science in both theory and practice. |
| brown laboratory of chemistry purdue: Freedom's Laboratory Audra J. Wolfe, 2020-08-04 The Cold War ended long ago, but the language of science and freedom continues to shape public debates over the relationship between science and politics in the United States. Scientists like to proclaim that science knows no borders. Scientific researchers follow the evidence where it leads, their conclusions free of prejudice or ideology. But is that really the case? In Freedom's Laboratory, Audra J. Wolfe shows how these ideas were tested to their limits in the high-stakes propaganda battles of the Cold War. Wolfe examines the role that scientists, in concert with administrators and policymakers, played in American cultural diplomacy after World War II. During this period, the engines of US propaganda promoted a vision of science that highlighted empiricism, objectivity, a commitment to pure research, and internationalism. Working (both overtly and covertly, wittingly and unwittingly) with governmental and private organizations, scientists attempted to decide what, exactly, they meant when they referred to scientific freedom or the US ideology. More frequently, however, they defined American science merely as the opposite of Communist science. Uncovering many startling episodes of the close relationship between the US government and private scientific groups, Freedom's Laboratory is the first work to explore science's link to US propaganda and psychological warfare campaigns during the Cold War. Closing in the present day with a discussion of the 2017 March for Science and the prospects for science and science diplomacy in the Trump era, the book demonstrates the continued hold of Cold War thinking on ideas about science and politics in the United States. |
| brown laboratory of chemistry purdue: Motherhood, the Elephant in the Laboratory Emily Monosson, 2011-08-15 About half of the undergraduate and roughly 40 percent of graduate degree recipients in science and engineering are women. As increasing numbers of these women pursue research careers in science, many who choose to have children discover the unique difficulties of balancing a professional life in these highly competitive (and often male-dominated) fields with the demands of motherhood. Although this issue directly affects the career advancement of women scientists, it is rarely discussed as a professional concern, leaving individuals to face the dilemma on their own. To address this obvious but unacknowledged crisis—the elephant in the laboratory, according to one scientist—Emily Monosson, an independent toxicologist, has brought together 34 women scientists from overlapping generations and several fields of research—including physics, chemistry, geography, paleontology, and ecology, among others—to share their experiences. From women who began their careers in the 1970s and brought their newborns to work, breastfeeding them under ponchos, to graduate students today, the authors of the candid essays written for this groundbreaking volume reveal a range of career choices: the authors work part-time and full-time; they opt out and then opt back in; they become entrepreneurs and job share; they teach high school and have achieved tenure. The personal stories that comprise Motherhood, the Elephant in the Laboratory not only show the many ways in which women can successfully combine motherhood and a career in science but also address and redefine what it means to be a successful scientist. These valuable narratives encourage institutions of higher education and scientific research to accommodate the needs of scientists who decide to have children. |
| brown laboratory of chemistry purdue: Multiphase Environmental Chemistry in the Atmosphere Sherri W. Hunt, Alexander Laskin, Sergey A. Nizkorodov, 2019 This book highlights new cross-disciplinary advances in aerosol chemistry that involve more than one phase, for example, unique chemical processes occurring on gas-solid and liquid-solid interfaces. |
| brown laboratory of chemistry purdue: Principles of Mass Spectrometry Applied to Biomolecules Chava Lifshitz, Julia Laskin, 2006-10-27 An extensive compilation of articles by leading professionals, this reference explains the fundamental principles of mass spectrometry as they relate to the life sciences. Topics covered include spectroscopy, energetics and mechanisms of peptide fragmentation, electron capture dissociation, ion-ion and ion-molecule reactions, reaction dynamics, collisional activation, soft-landing, protein structure and interactions, thermochemistry, and more. The book empowers readers to develop new ways of using these techniques. |
| brown laboratory of chemistry purdue: Selected Topics in Mass Spectrometry in the Biomolecular Sciences Richard M. Caprioli, A. Malorni, G. Sindona, 2012-12-06 Many fundamental aspects of the methods used in mass spectrometry are here presented by outstanding scientists, with reference to very recent developments. The principles and applications of electrospray, ion spray and MALDI ionization technique are presented, together with optimised GC/MS interfacing systems and tools for quantitative analysis. A comprehensive treatment of modern instrumentation for mass analysis and detection is also included. The major part of the book deals with bioanalytical applications to peptides, proteins, oligonucleotides, polysaccharides, lipids and plant metabolites. Several papers are devoted to the evaluation of adduct formation between DNA and carcinogens. Environmental applications are also included, with examples of some specific cases. Fundamentals and applications are treated with the same degree of depth: the first two parts of the book therefore provide a basis for the understanding of the biomolecular applications section. Audience: Ideal for advanced graduate students of chemistry who have learned some basic mass spectrometry. Also useful for Ph.D. students in chemistry, biology and medicine. Of value to researchers in academic and industrial laboratories. |
| brown laboratory of chemistry purdue: The Nonclassical Ion Problem Herbert C. Brown, 2012-12-06 1. That Fascinating Nonclassical Ion Problem.- 1.1. Introduction.- 1.2. Origins.- 1.3. The Nonclassical Ion Era.- 1.4. Steric Assistance.- 1.5. An Alternative Interpretation.- 1.6. The Rococo Period of Carbonium Ion Structures.- 1.7. Difficulties in Challenging an Accepted Theory.- 1.8. Further Difficulties-A Soft Theory.- 1.9. Still Further Difficulties-Selective Reviews.- 1.10. Conclusion.- Comments.- 2. Steric Assistance in Solvolytic Processes.- 2.1. Introduction.- 2.2. Steric Assistance in the Solvolysis of Highly Branched Alkyl Derivatives.- 2.3. Steric Assistance in the Relative Effec. |
| brown laboratory of chemistry purdue: March's Advanced Organic Chemistry Michael B. Smith, Jerry March, 2007-01-29 The Sixth Edition of a classic in organic chemistry continues its tradition of excellence Now in its sixth edition, March's Advanced Organic Chemistry remains the gold standard in organic chemistry. Throughout its six editions, students and chemists from around the world have relied on it as an essential resource for planning and executing synthetic reactions. The Sixth Edition brings the text completely current with the most recent organic reactions. In addition, the references have been updated to enable readers to find the latest primary and review literature with ease. New features include: More than 25,000 references to the literature to facilitate further research Revised mechanisms, where required, that explain concepts in clear modern terms Revisions and updates to each chapter to bring them all fully up to date with the latest reactions and discoveries A revised Appendix B to facilitate correlating chapter sections with synthetic transformations |
| brown laboratory of chemistry purdue: Handbook of Advanced Plasma Processing Techniques R.J. Shul, S.J. Pearton, 2011-06-28 Pattern transfer by dry etching and plasma-enhanced chemical vapor de position are two of the cornerstone techniques for modern integrated cir cuit fabrication. The success of these methods has also sparked interest in their application to other techniques, such as surface-micromachined sen sors, read/write heads for data storage and magnetic random access memory (MRAM). The extremely complex chemistry and physics of plasmas and their interactions with the exposed surfaces of semiconductors and other materi als is often overlooked at the manufacturing stage. In this case, the process is optimized by an informed trial-and-error approach which relies heavily on design-of-experiment techniques and the intuition of the process engineer. The need for regular cleaning of plasma reactors to remove built-up reaction or precursor gas products adds an extra degree of complexity because the interaction of the reactive species in the plasma with the reactor walls can also have a strong effect on the number of these species available for etching or deposition. Since the microelectronics industry depends on having high process yields at each step of the fabrication process, it is imperative that a full understanding of plasma etching and deposition techniques be achieved. |
| brown laboratory of chemistry purdue: Practical Aspects of Ion Trap Mass Spectrometry, Volume I Raymond E. March, John F.J Todd, 2024-11-01 Fundamentals of Ion Trap Mass Spectrometry presents an account of the development and theory of the quadrupole ion trap and its utilization as an ion storage device, a reactor for ion/molecular reactions, and a mass spectrometer. It also expands the appreciation of ion traps from that of a unique arrangement of electrodes of hyperbolic form (and having a pure quadrupole field) to a series of ion traps having fields with hexapole and octopole components and introduces the practical ion trapping device in which electrode spacing has been increased. The fundamentals of ion trap are covered in four chapters, beginning with the origin of the ion trap, its development and operating principles, and improvements in performance. The second part focuses on the environment within the ion trap -- the movement of ions within the trap -- and how this movement is modified by repeated collisions of the ions with buffer gas atoms of helium, and on the collisions of ions with molecules that lead to chemical change. The critical role of collisions in focusing the ion cloud for subsequent operations is emphasized. This important reference presents a coherent picture of the present status of research in the ion trapping field to facilitate the entree of potential ion trappers and provide a backdrop for ion trap research and development in the future. |
| brown laboratory of chemistry purdue: Materials and Mechanical Engineering Guo Long Ruan, 2014-02-19 Selected, peer reviewed papers from the International Workshop on Materials and Mechanical Engineering (WMME 2013), November 20-22, 2013, Xianning, China |
Brown University
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Brown University
Brown is a leading research university, home to world-renowned faculty and also an innovative educational …
About Brown - Brown University
Founded in 1764, Brown is a leading nonprofit research university, home to world-renowned faculty, and also an …
Academics - Brown University
Brown offers more than 80 programs, what some colleges call majors. You'll sample courses in a wide range of …
Admission and Aid - Brown University
Brown is renowned for its distinctive undergraduate experience rooted in its flexible yet rigorous Open …
Undergraduate Admission | Brown University
At Brown, we invite you to develop your own personalized course of study. You’ll sample rigorous courses in a …
