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| computers biology and medicine: Artificial Intelligence in Medicine David Riaño, Szymon Wilk, Annette ten Teije, 2019-06-19 This book constitutes the refereed proceedings of the 17th Conference on Artificial Intelligence in Medicine, AIME 2019, held in Poznan, Poland, in June 2019. The 22 revised full and 31 short papers presented were carefully reviewed and selected from 134 submissions. The papers are organized in the following topical sections: deep learning; simulation; knowledge representation; probabilistic models; behavior monitoring; clustering, natural language processing, and decision support; feature selection; image processing; general machine learning; and unsupervised learning. |
| computers biology and medicine: Biomedical Computing Joseph A. November, 2012-06-01 Winner of the Computer History Museum Prize of the Special Interest Group: Computers, Information, and Society Imagine biology and medicine today without computers. What would laboratory work be like if electronic databases and statistical software did not exist? Would disciplines like genomics even be feasible if we lacked the means to manage and manipulate huge volumes of digital data? How would patients fare in a world absent CT scans, programmable pacemakers, and computerized medical records? Today, computers are a critical component of almost all research in biology and medicine. Yet, just fifty years ago, the study of life was by far the least digitized field of science, its living subject matter thought too complex and dynamic to be meaningfully analyzed by logic-driven computers. In this long-overdue study, historian Joseph November explores the early attempts, in the 1950s and 1960s, to computerize biomedical research in the United States. Computers and biomedical research are now so intimately connected that it is difficult to imagine when such critical work was offline. Biomedical Computing transports readers back to such a time and investigates how computers first appeared in the research lab and doctor's office. November examines the conditions that made possible the computerization of biology—including strong technological, institutional, and political support from the National Institutes of Health—and shows not only how digital technology transformed the life sciences but also how the intersection of the two led to important developments in computer architecture and software design. The history of this phenomenon has been only vaguely understood. November's thoroughly researched and lively study makes clear for readers the motives behind computerizing the study of life and how that technology profoundly affects biomedical research today. |
| computers biology and medicine: Biomedical Informatics Edward H. Shortliffe, James J. Cimino, 2006-12-02 This book focuses on the role of computers in the provision of medical services. It provides both a conceptual framework and a practical approach for the implementation and management of IT used to improve the delivery of health care. Inspired by a Stanford University training program, it fills the need for a high quality text in computers and medicine. It meets the growing demand by practitioners, researchers, and students for a comprehensive introduction to key topics in the field. Completely revised and expanded, this work includes several new chapters filled with brand new material. |
| computers biology and medicine: Biomedical Informatics Edward H. Shortliffe, James J. Cimino, 2013-12-02 The practice of modern medicine and biomedical research requires sophisticated information technologies with which to manage patient information, plan diagnostic procedures, interpret laboratory results, and carry out investigations. Biomedical Informatics provides both a conceptual framework and a practical inspiration for this swiftly emerging scientific discipline at the intersection of computer science, decision science, information science, cognitive science, and biomedicine. Now revised and in its third edition, this text meets the growing demand by practitioners, researchers, and students for a comprehensive introduction to key topics in the field. Authored by leaders in medical informatics and extensively tested in their courses, the chapters in this volume constitute an effective textbook for students of medical informatics and its areas of application. The book is also a useful reference work for individual readers needing to understand the role that computers can play in the provision of clinical services and the pursuit of biological questions. The volume is organized so as first to explain basic concepts and then to illustrate them with specific systems and technologies. |
| computers biology and medicine: Visual Computing for Medicine Bernhard Preim, Charl P Botha, 2013-11-07 Visual Computing for Medicine, Second Edition, offers cutting-edge visualization techniques and their applications in medical diagnosis, education, and treatment. The book includes algorithms, applications, and ideas on achieving reliability of results and clinical evaluation of the techniques covered. Preim and Botha illustrate visualization techniques from research, but also cover the information required to solve practical clinical problems. They base the book on several years of combined teaching and research experience. This new edition includes six new chapters on treatment planning, guidance and training; an updated appendix on software support for visual computing for medicine; and a new global structure that better classifies and explains the major lines of work in the field. - Complete guide to visual computing in medicine, fully revamped and updated with new developments in the field - Illustrated in full color - Includes a companion website offering additional content for professors, source code, algorithms, tutorials, videos, exercises, lessons, and more |
| computers biology and medicine: Physics in Biology and Medicine Paul Davidovits, 2008 This third edition covers topics in physics as they apply to the life sciences, specifically medicine, physiology, nursing and other applied health fields. It includes many figures, examples and illustrative problems and appendices which provide convenient access to the most important concepts of mechanics, electricity, and optics. |
| computers biology and medicine: Bioinformatics Basics Lukas K. Buehler, Hooman H. Rashidi, 2005-06-23 Every researcher in genomics and proteomics now has access to public domain databases containing literally billions of data entries. However, without the right analytical tools, and an understanding of the biological significance of the data, cataloging and interpreting the molecular evolutionary processes buried in those databases is difficult, if |
| computers biology and medicine: Intelligence-Based Medicine Anthony C. Chang, 2020-06-27 Intelligence-Based Medicine: Data Science, Artificial Intelligence, and Human Cognition in Clinical Medicine and Healthcare provides a multidisciplinary and comprehensive survey of artificial intelligence concepts and methodologies with real life applications in healthcare and medicine. Authored by a senior physician-data scientist, the book presents an intellectual and academic interface between the medical and the data science domains that is symmetric and balanced. The content consists of basic concepts of artificial intelligence and its real-life applications in a myriad of medical areas as well as medical and surgical subspecialties. It brings section summaries to emphasize key concepts delineated in each section; mini-topics authored by world-renowned experts in the respective key areas for their personal perspective; and a compendium of practical resources, such as glossary, references, best articles, and top companies. The goal of the book is to inspire clinicians to embrace the artificial intelligence methodologies as well as to educate data scientists about the medical ecosystem, in order to create a transformational paradigm for healthcare and medicine by using this emerging new technology. - Covers a wide range of relevant topics from cloud computing, intelligent agents, to deep reinforcement learning and internet of everything - Presents the concepts of artificial intelligence and its applications in an easy-to-understand format accessible to clinicians and data scientists - Discusses how artificial intelligence can be utilized in a myriad of subspecialties and imagined of the future - Delineates the necessary elements for successful implementation of artificial intelligence in medicine and healthcare |
| computers biology and medicine: Use of Computers in Biology and Medicine Robert Steven Ledley, 1965 |
| computers biology and medicine: The Computer-Based Patient Record Committee on Improving the Patient Record, Institute of Medicine, 1997-10-28 Most industries have plunged into data automation, but health care organizations have lagged in moving patients' medical records from paper to computers. In its first edition, this book presented a blueprint for introducing the computer-based patient record (CPR). The revised edition adds new information to the original book. One section describes recent developments, including the creation of a computer-based patient record institute. An international chapter highlights what is new in this still-emerging technology. An expert committee explores the potential of machine-readable CPRs to improve diagnostic and care decisions, provide a database for policymaking, and much more, addressing these key questions: Who uses patient records? What technology is available and what further research is necessary to meet users' needs? What should government, medical organizations, and others do to make the transition to CPRs? The volume also explores such issues as privacy and confidentiality, costs, the need for training, legal barriers to CPRs, and other key topics. |
| computers biology and medicine: Computer Simulation and Data Analysis in Molecular Biology and Biophysics Victor Bloomfield, 2009-06-05 This book provides an introduction to two important aspects of modern bioch- istry, molecular biology, and biophysics: computer simulation and data analysis. My aim is to introduce the tools that will enable students to learn and use some f- damental methods to construct quantitative models of biological mechanisms, both deterministicandwithsomeelementsofrandomness;tolearnhowconceptsofpr- ability can help to understand important features of DNA sequences; and to apply a useful set of statistical methods to analysis of experimental data. The availability of very capable but inexpensive personal computers and software makes it possible to do such work at a much higher level, but in a much easier way, than ever before. TheExecutiveSummaryofthein?uential2003reportfromtheNationalAcademy of Sciences, “BIO 2010: Transforming Undergraduate Education for Future - search Biologists” [12], begins The interplay of the recombinant DNA, instrumentation, and digital revolutions has p- foundly transformed biological research. The con?uence of these three innovations has led to important discoveries, such as the mapping of the human genome. How biologists design, perform, and analyze experiments is changing swiftly. Biological concepts and models are becoming more quantitative, and biological research has become critically dependent on concepts and methods drawn from other scienti?c disciplines. The connections between the biological sciences and the physical sciences, mathematics, and computer science are rapidly becoming deeper and more extensive. |
| computers biology and medicine: Bioinformatics and Computational Biology Solutions Using R and Bioconductor Robert Gentleman, Vincent Carey, Wolfgang Huber, Rafael Irizarry, Sandrine Dudoit, 2005-12-29 Full four-color book. Some of the editors created the Bioconductor project and Robert Gentleman is one of the two originators of R. All methods are illustrated with publicly available data, and a major section of the book is devoted to fully worked case studies. Code underlying all of the computations that are shown is made available on a companion website, and readers can reproduce every number, figure, and table on their own computers. |
| computers biology and medicine: Advanced Scientific Computing in BASIC with Applications in Chemistry, Biology and Pharmacology P Valko, S. Vajda, 1989-01-01 This book gives a practical introduction to numerical methods and presents BASIC subroutines for real-life computations in the areas of chemistry, biology, and pharmacology. The choice of BASIC as the programming language is motivated by its simplicity, its availability on all personal computers and by its power in data acquisition. While most of the scientific packages currently available in BASIC date back to the period of limited memory and speed, the subroutines presented here can handle a broad range of realistic problems with the power and sophistication needed by professionals and with simple, step-by-step instructions for students and beginners.Please note that a diskette containing the 37 program modules and 39 sample programs listed in the book is no longer available.The main task considered in the book is that of extracting useful information from measurements via modelling, simulation, and statistical data evaluations. Efficient and robust numerical methods have been chosen to solve related problems in numerical algebra, nonlinear equations and optimization, parameter estimation, signal processing, and differential equations. For each class of routines an introduction to the relevant theory and techniques is given, so that the reader will recognise and use the appropriate method for solving his or her particular problem. Simple examples illustrate the use and applicability of each method. |
| computers biology and medicine: The HLA Complex in Biology and Medicine Narinder K Mehra, 2010-11-26 A comprehensive guide to the HLA (Human Leukocyte Antigen) system for immunologists and clinicians, this book contains up-to-date information on the MHC (Major Histocompatibility Complex) and its role in the immune response and in various diseases. The book explores the biological significance and role of the HLA system in organ and haematopoietic stem cell transplantation management. This volume is an invaluable guide to the full spectrum of HLA-related science while also serving as a conceptual and technical resource for those involved in HLA-related research and in clinical or surgical practice. In addition, it will be a primary point of contact for individuals working in other areas who suddenly find that their research is drawing them into the complexities of HLA genetics. |
| computers biology and medicine: Catalyzing Inquiry at the Interface of Computing and Biology National Research Council, Division on Engineering and Physical Sciences, Computer Science and Telecommunications Board, Committee on Frontiers at the Interface of Computing and Biology, 2006-01-01 Advances in computer science and technology and in biology over the last several years have opened up the possibility for computing to help answer fundamental questions in biology and for biology to help with new approaches to computing. Making the most of the research opportunities at the interface of computing and biology requires the active participation of people from both fields. While past attempts have been made in this direction, circumstances today appear to be much more favorable for progress. To help take advantage of these opportunities, this study was requested of the NRC by the National Science Foundation, the Department of Defense, the National Institutes of Health, and the Department of Energy. The report provides the basis for establishing cross-disciplinary collaboration between biology and computing including an analysis of potential impediments and strategies for overcoming them. The report also presents a wealth of examples that should encourage students in the biological sciences to look for ways to enable them to be more effective users of computing in their studies. |
| computers biology and medicine: Analysis of Physiological Systems Vasilis Marmarelis, 1978-07-01 |
| computers biology and medicine: Computational Biology Scott T. Kelley, Dennis Didulo, 2018-01-01 This textbook is for anyone who needs to learn the basics of bioinformatics—the use of computational methods to better understand biological systems. Computational Biology covers the principles and applications of the computational methods used to study DNA, RNA, and proteins, including using biological databases such as NCBI and UniProt; performing BLAST, sequence alignments, and structural predictions; and creating phylogenetic trees. It includes a primer that can be used as a jumping off point for learning computer programming for bioinformatics. This text can be used as a self-study guide, as a course focused on computational methods in biology/bioinformatics, or to supplement general courses that touch on topics included within the book. Computational Biology's robust interactive online components “gamify” the study of bioinformatics, allowing the reader to practice randomly generated problems on their own time to build confidence and skill and gain practical real-world experience. The online component also assures that the content being taught is up to date and accurately reflects the ever-changing landscape of bioinformatics web-based programs. |
| computers biology and medicine: Visualization in Medicine Bernhard Preim, Dirk Bartz, 2007-06-21 Visualization in Medicine is the first book on visualization and its application to problems in medical diagnosis, education, and treatment. The book describes the algorithms, the applications and their validation (how reliable are the results?), and the clinical evaluation of the applications (are the techniques useful?). It discusses visualization techniques from research literature as well as the compromises required to solve practical clinical problems. The book covers image acquisition, image analysis, and interaction techniques designed to explore and analyze the data. The final chapter shows how visualization is used for planning liver surgery, one of the most demanding surgical disciplines. The book is based on several years of the authors' teaching and research experience. Both authors have initiated and lead a variety of interdisciplinary projects involving computer scientists and medical doctors, primarily radiologists and surgeons.* A core field of visualization and graphics missing a dedicated book until now* Written by pioneers in the field and illustrated in full color* Covers theory as well as practice |
| computers biology and medicine: Netter's Advanced Head & Neck Flash Cards Updated Edition E-Book Neil S. Norton, 2014-04-14 With its many complex structures, the anatomy of the head and neck is one of the most challenging areas of human anatomy to study and master. These 248 flash cards are the perfect streamlined review to help you learn head and neck anatomy as well as common diseases and disorders of this region easily, efficiently, and at your own rate of study. Netter's Advanced Head and Neck Anatomy Flash Cards is your perfect quick resource for a fast and fun review at any stage of your healthcare career. Test and teach yourself at your own pace. Learn visually using many of Netter's famous anatomy and pathology illustrations of the head, neck, and special senses. Get clinically relevant knowledge with additional diagnostic images and advanced accompanying text and tables. Pre-punched holes make it easy to carry selected groups of cards with you. |
| computers biology and medicine: Health Informatics: Practical Guide for Healthcare and Information Technology Professionals (Sixth Edition) Robert E. Hoyt, Ann K. Yoshihashi, 2014 Health Informatics (HI) focuses on the application of Information Technology (IT) to the field of medicine to improve individual and population healthcare delivery, education and research. This extensively updated fifth edition reflects the current knowledge in Health Informatics and provides learning objectives, key points, case studies and references. |
| computers biology and medicine: Guide for the Care and Use of Laboratory Animals National Research Council, Division on Earth and Life Studies, Institute for Laboratory Animal Research, Committee for the Update of the Guide for the Care and Use of Laboratory Animals, 2011-01-27 A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates. |
| computers biology and medicine: Essentials of Bioinformatics, Volume I Noor Ahmad Shaik, Khalid Rehman Hakeem, Babajan Banaganapalli, Ramu Elango, 2019-03-27 Bioinformatics is an integrative field of computer science, genetics, genomics, proteomics, and statistics, which has undoubtedly revolutionized the study of biology and medicine in past decades. It mainly assists in modeling, predicting and interpreting large multidimensional biological data by utilizing advanced computational methods. Despite its enormous potential, bioinformatics is not widely integrated into the academic curriculum as most life science students and researchers are still not equipped with the necessary knowledge to take advantage of this powerful tool. Hence, the primary purpose of our book is to supplement this unmet need by providing an easily accessible platform for students and researchers starting their career in life sciences. This book aims to avoid sophisticated computational algorithms and programming. Instead, it mostly focuses on simple DIY analysis and interpretation of biological data with personal computers. Our belief is that once the beginners acquire these basic skillsets, they will be able to handle most of the bioinformatics tools for their research work and to better understand their experimental outcomes. Unlike other bioinformatics books which are mostly theoretical, this book provides practical examples for the readers on state-of-the-art open source tools to solve biological problems. Flow charts of experiments, graphical illustrations, and mock data are included for quick reference. Volume I is therefore an ideal companion for students and early stage professionals wishing to master this blooming field. |
| computers biology and medicine: Computing the Future National Research Council, Computer Science and Telecommunications Board, Committee to Assess the Scope and Direction of Computer Science and Technology, 1992-02-01 Computers are increasingly the enabling devices of the information revolution, and computing is becoming ubiquitous in every corner of society, from manufacturing to telecommunications to pharmaceuticals to entertainment. Even more importantly, the face of computing is changing rapidly, as even traditional rivals such as IBM and Apple Computer begin to cooperate and new modes of computing are developed. Computing the Future presents a timely assessment of academic computer science and engineering (CS&E), examining what should be done to ensure continuing progress in making discoveries that will carry computing into the twenty-first century. Most importantly, it advocates a broader research and educational agenda that builds on the field's impressive accomplishments. The volume outlines a framework of priorities for CS&E, along with detailed recommendations for education, funding, and leadership. A core research agenda is outlined for these areas: processors and multiple-processor systems, data communications and networking, software engineering, information storage and retrieval, reliability, and user interfaces. This highly readable volume examines: Computer science and engineering as a discipline-how computer scientists and engineers are pushing back the frontiers of their field. How CS&E must change to meet the challenges of the future. The influence of strategic investment by federal agencies in CS&E research. Recent structural changes that affect the interaction of academic CS&E and the business environment. Specific examples of interdisciplinary and applications research in four areas: earth sciences and the environment, computational biology, commercial computing, and the long-term goal of a national electronic library. The volume provides a detailed look at undergraduate CS&E education, highlighting the limitations of four-year programs, and discusses the emerging importance of a master's degree in CS&E and the prospects for broadening the scope of the Ph.D. It also includes a brief look at continuing education. |
| computers biology and medicine: Handbook of Physics in Medicine and Biology Robert Splinter, 2010-04-05 In considering ways that physics has helped advance biology and medicine, what typically comes to mind are the various tools used by researchers and clinicians. We think of the optics put to work in microscopes, endoscopes, and lasers; the advanced diagnostics permitted through magnetic, x-ray, and ultrasound imaging; and even the nanotools, that a |
| computers biology and medicine: Biomedical Computing W. J. Perkins, 1977 |
| computers biology and medicine: Topic Detection and Tracking James Allan, 2012-12-06 Topic Detection and Tracking: Event-based Information Organization brings together in one place state-of-the-art research in Topic Detection and Tracking (TDT). This collection of technical papers from leading researchers in the field not only provides several chapters devoted to the research program and its evaluation paradigm, but also presents the most current research results and describes some of the remaining open challenges. Topic Detection and Tracking: Event-based Information Organization is an excellent reference for researchers and practitioners in a variety of fields related to TDT, including information retrieval, automatic speech recognition, machine learning, and information extraction. |
| computers biology and medicine: Systemic Approaches in Bioinformatics and Computational Systems Biology Paola Lecca, Dan Tulpan, Kanagasabai Rajaraman, 2012 This book presents new techniques that have resulted from the application of computer science methods to the organization and interpretation of biological data, covering three subject areas: bioinformatics, computational biology, and computational systems biology-- |
| computers biology and medicine: Topology for Computing Afra J. Zomorodian, 2005-01-10 The emerging field of computational topology utilizes theory from topology and the power of computing to solve problems in diverse fields. Recent applications include computer graphics, computer-aided design (CAD), and structural biology, all of which involve understanding the intrinsic shape of some real or abstract space. A primary goal of this book is to present basic concepts from topology and Morse theory to enable a non-specialist to grasp and participate in current research in computational topology. The author gives a self-contained presentation of the mathematical concepts from a computer scientist's point of view, combining point set topology, algebraic topology, group theory, differential manifolds, and Morse theory. He also presents some recent advances in the area, including topological persistence and hierarchical Morse complexes. Throughout, the focus is on computational challenges and on presenting algorithms and data structures when appropriate. |
| computers biology and medicine: Bioinformatics and Computational Biology Basant K. Tiwary, 2021-11-23 This textbook introduces fundamental concepts of bioinformatics and computational biology to the students and researchers in biology, medicine, veterinary science, agriculture, and bioengineering . The respective chapters provide detailed information on biological databases, sequence alignment, molecular evolution, next-generation sequencing, systems biology, and statistical computing using R. The book also presents a case-based discussion on clinical, veterinary, agricultural bioinformatics, and computational bioengineering for application-based learning in the respective fields. Further, it offers readers guidance on reconstructing and analysing biological networks and highlights computational methods used in systems medicine and genome-wide association mapping of diseases. Given its scope, this textbook offers an essential introductory book on bioinformatics and computational biology for undergraduate and graduate students in the life sciences, botany, zoology, physiology, biotechnology, bioinformatics, and genomic science as well as systems biology, bioengineering and the agricultural, and veterinary sciences. |
| computers biology and medicine: Atlas of Clinical Gross Anatomy E-Book Kenneth P. Moses, Pedro B. Nava, John C. Banks, Darrell K. Petersen, 2012-05-29 Atlas of Clinical Gross Anatomy uses over 500 incredibly well-executed and superb dissection photos and illustrations to guide you through all the key structures you'll need to learn in your gross anatomy course. This medical textbook helps you master essential surface, gross, and radiologic anatomy concepts through high-quality photos, digital enhancements, and concise text introductions throughout. - Get a clear understanding of surface, gross, and radiologic anatomy with a resource that's great for use before, during, and after lab work, in preparation for examinations, and later on as a primer for clinical work. - Learn as intuitively as possible with large, full-page photos for effortless comprehension. No more confusion and peering at small, closely cropped pictures! - Easily distinguish highlighted structures from the background in each dissection with the aid of digitally color-enhanced images. - See structures the way they present in the anatomy lab with specially commissioned dissections, all done using freshly dissected cadavers prepared using low-alcohol fixative. - Bridge the gap between gross anatomy and clinical practice with clinical correlations throughout. - Master anatomy efficiently with one text covering all you need to know, from surface to radiologic anatomy, that's ideal for shortened anatomy courses. - Review key structures quickly thanks to detailed dissection headings and unique icon navigation. - Access the full text and self assessment questions at studentconsult.com. |
| computers biology and medicine: Medical Image Analysis Alejandro Frangi, Jerry Prince, Milan Sonka, 2023-09-20 Medical Image Analysis presents practical knowledge on medical image computing and analysis as written by top educators and experts. This text is a modern, practical, self-contained reference that conveys a mix of fundamental methodological concepts within different medical domains. Sections cover core representations and properties of digital images and image enhancement techniques, advanced image computing methods (including segmentation, registration, motion and shape analysis), machine learning, how medical image computing (MIC) is used in clinical and medical research, and how to identify alternative strategies and employ software tools to solve typical problems in MIC. - An authoritative presentation of key concepts and methods from experts in the field - Sections clearly explaining key methodological principles within relevant medical applications - Self-contained chapters enable the text to be used on courses with differing structures - A representative selection of modern topics and techniques in medical image computing - Focus on medical image computing as an enabling technology to tackle unmet clinical needs - Presentation of traditional and machine learning approaches to medical image computing |
| computers biology and medicine: DNA Computing Models Zoya Ignatova, Israel Martínez-Pérez, Karl-Heinz Zimmermann, 2008-06-11 Sir Francis Crick would undoubtedly be at the front of the line ordering this fascinating book. Being one of the discoverers of DNA, he would be amazed at how his work has been applied to mankind's most important invention, the computer. In this excellent text, the reader is given a comprehensive introduction to the field of DNA computing. The book emphasizes computational methods to tackle central problems of DNA computing, such as controlling living cells, building patterns, and generating nanomachines. It also includes laboratory-scale human-operated models of computation, as well as a description of the first experiment of DNA computation conducted by Adleman in 1994. |
| computers biology and medicine: Free Radicals in Biology and Medicine Barry Halliwell, John M. C. Gutteridge, 2015 Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and the roles played by reactive species in signal transduction, cell survival, death, human reproduction, defence mechanisms of animals and plants against pathogens, and other important biological events. The methodologies available to measure reactive species and oxidative damage (and their potential pitfalls) have been fully updated, as have the topics of phagocyte ROS production, NADPH oxidase enzymes, and toxicology. There is a detailed and critical evaluation of the role of free radicals and other reactive species in human diseases, especially cancer, cardiovascular, chronic inflammatory and neurodegenerative diseases. New aspects of ageing are discussed in the context of the free radical theory of ageing. This book is recommended as a comprehensive introduction to the field for students, educators, clinicians, and researchers. It will also be an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences. |
| computers biology and medicine: Computer Modeling in Bioengineering Miloš Kojić, Nenad Filipović, Boban Stojanović, Nikola Kojić, 2008-06-09 Bioengineering is a broad-based engineering discipline that applies engineering principles and design to challenges in human health and medicine, dealing with bio-molecular and molecular processes, product design, sustainability and analysis of biological systems. Applications that benefit from bioengineering include medical devices, diagnostic equipment and biocompatible materials, amongst others. Computer Modeling in Bioengineering offers a comprehensive reference for a large number of bioengineering topics, presenting important computer modeling problems and solutions for research and medical practice. Starting with basic theory and fundamentals, the book progresses to more advanced methods and applications, allowing the reader to become familiar with different topics to the desired extent. It includes unique and original topics alongside classical computational modeling methods, and each application is structured to explain the physiological background, phenomena that are to be modeled, the computational methods used in the model, and solutions of typical cases. The accompanying software contains over 80 examples, enabling the reader to study a topic using the theory and examples, then run the software to solve the same, or similar examples, varying the model parameters within a given range in order to investigate the problem at greater depth. Tutorials also guide the user in further exploring the modeled problem; these features promote easier learning and will help lecturers with presentations. Computer Modeling in Bioengineering includes computational methods for modelling bones, tissues, muscles, cardiovascular components, cartilage, cells and cancer nanotechnology as well as many other applications. It bridges the gap between engineering, biology and medicine, and will appeal not only to bioengineering students, lecturers and researchers, but also medical students and clinical researchers. |
| computers biology and medicine: Marijuana and Medicine Institute of Medicine, 1999-07-10 The medical use of marijuana is surrounded by a cloud of social, political, and religious controversy, which obscures the facts that should be considered in the debate. This book summarizes what we know about marijuana from evidence-based medicineâ€the harm it may do and the relief it may bring to patients. The book helps the reader understand not only what science has to say about medical marijuana but also the logic behind the scientific conclusions. Marijuana and Medicine addresses the science base and the therapeutic effects of marijuana use for medical conditions such as glaucoma and multiple sclerosis. It covers marijuana's mechanism of action, acute and chronic effects on health and behavior, potential adverse effects, efficacy of different delivery systems, analysis of the data about marijuana as a gateway drug, and the prospects for developing cannabinoid drugs. The book evaluates how well marijuana meets accepted standards for medicine and considers the conclusions of other blue-ribbon panels. Full of useful facts, this volume will be important to anyone interested in informed debate about the medical use of marijuana: advocates and opponents as well as policymakers, regulators, and health care providers. |
| computers biology and medicine: Computational Technology for Effective Health Care National Research Council, Division on Engineering and Physical Sciences, Computer Science and Telecommunications Board, Committee on Engaging the Computer Science Research Community in Health Care Informatics, 2009-02-24 Despite a strong commitment to delivering quality health care, persistent problems involving medical errors and ineffective treatment continue to plague the industry. Many of these problems are the consequence of poor information and technology (IT) capabilities, and most importantly, the lack cognitive IT support. Clinicians spend a great deal of time sifting through large amounts of raw data, when, ideally, IT systems would place raw data into context with current medical knowledge to provide clinicians with computer models that depict the health status of the patient. Computational Technology for Effective Health Care advocates re-balancing the portfolio of investments in health care IT to place a greater emphasis on providing cognitive support for health care providers, patients, and family caregivers; observing proven principles for success in designing and implementing IT; and accelerating research related to health care in the computer and social sciences and in health/biomedical informatics. Health care professionals, patient safety advocates, as well as IT specialists and engineers, will find this book a useful tool in preparation for crossing the health care IT chasm. |
| computers biology and medicine: Assessing and Responding to the Growth of Computer Science Undergraduate Enrollments National Academies of Sciences, Engineering, and Medicine, Division on Engineering and Physical Sciences, Computer Science and Telecommunications Board, Policy and Global Affairs, Board on Higher Education and Workforce, Committee on the Growth of Computer Science Undergraduate Enrollments, 2018-04-28 The field of computer science (CS) is currently experiencing a surge in undergraduate degree production and course enrollments, which is straining program resources at many institutions and causing concern among faculty and administrators about how best to respond to the rapidly growing demand. There is also significant interest about what this growth will mean for the future of CS programs, the role of computer science in academic institutions, the field as a whole, and U.S. society more broadly. Assessing and Responding to the Growth of Computer Science Undergraduate Enrollments seeks to provide a better understanding of the current trends in computing enrollments in the context of past trends. It examines drivers of the current enrollment surge, relationships between the surge and current and potential gains in diversity in the field, and the potential impacts of responses to the increased demand for computing in higher education, and it considers the likely effects of those responses on students, faculty, and institutions. This report provides recommendations for what institutions of higher education, government agencies, and the private sector can do to respond to the surge and plan for a strong and sustainable future for the field of CS in general, the health of the institutions of higher education, and the prosperity of the nation. |
| computers biology and medicine: DNA Computing and Molecular Programming Chris Thachuk, Yan Liu, 2019-07-30 This book constitutes the refereed proceedings of the 25th International Conference on DNA Computing and Molecular Programming, DNA 25, held in Seattle, WA, USA, in August 2019. The 12 full papers presented were carefully selected from 19 submissions. The papers cover a wide range of topics relating to biomolecular computing such as algorithms and models for computation on biomolecular systems; computational processes in vitro and in vivo; molecular switches, gates, devices, and circuits; molecular folding and self-assembly of nanostructures; analysis and theoretical models of laboratory techniques; molecular motors and molecular robotics; information storage; studies of fault-tolerance and error correction; software tools for analysis, simulation, anddesign; synthetic biology and in vitro evolution; and applications in engineering, physics, chemistry, biology, and medicine. |
| computers biology and medicine: Opportunities in Biology National Research Council, Division on Earth and Life Studies, Commission on Life Sciences, Board on Biology, Committee on Research Opportunities in Biology, 1989-01-01 Biology has entered an era in which interdisciplinary cooperation is at an all-time high, practical applications follow basic discoveries more quickly than ever before, and new technologiesâ€recombinant DNA, scanning tunneling microscopes, and moreâ€are revolutionizing the way science is conducted. The potential for scientific breakthroughs with significant implications for society has never been greater. Opportunities in Biology reports on the state of the new biology, taking a detailed look at the disciplines of biology; examining the advances made in medicine, agriculture, and other fields; and pointing out promising research opportunities. Authored by an expert panel representing a variety of viewpoints, this volume also offers recommendations on how to meet the infrastructure needsâ€for funding, effective information systems, and other supportâ€of future biology research. Exploring what has been accomplished and what is on the horizon, Opportunities in Biology is an indispensable resource for students, teachers, and researchers in all subdisciplines of biology as well as for research administrators and those in funding agencies. |
| computers biology and medicine: Bioinformatics Computing Bryan P. Bergeron, 2003 Comprehensive and concise, this handbook has chapters on computing visualization, large database designs, advanced pattern matching and other key bioinformatics techniques. It is a practical guide to computing in the growing field of Bioinformatics--the study of how information is represented and transmitted in biological systems, starting at the molecular level. |
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