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can breast cancer be treated with proton therapy: Surface Guided Radiation Therapy Jeremy David Page Hoisak, Adam Brent Paxton, Benjamin James Waghorn, Todd Pawlicki, 2020-02-13 Surface Guided Radiation Therapy provides a comprehensive overview of optical surface image guidance systems for radiation therapy. It serves as an introductory teaching resource for students and trainees, and a valuable reference for medical physicists, physicians, radiation therapists, and administrators who wish to incorporate surface guided radiation therapy (SGRT) into their clinical practice. This is the first book dedicated to the principles and practice of SGRT, featuring: Chapters authored by an internationally represented list of physicists, radiation oncologists and therapists, edited by pioneers and experts in SGRT Covering the evolution of localization systems and their role in quality and safety, current SGRT systems, practical guides to commissioning and quality assurance, clinical applications by anatomic site, and emerging topics including skin mark-less setups. Several dedicated chapters on SGRT for intracranial radiosurgery and breast, covering technical aspects, risk assessment and outcomes. Jeremy Hoisak, PhD, DABR is an Assistant Professor in the Department of Radiation Medicine and Applied Sciences at the University of California, San Diego. Dr. Hoisak’s clinical expertise includes radiosurgery and respiratory motion management. Adam Paxton, PhD, DABR is an Assistant Professor in the Department of Radiation Oncology at the University of Utah. Dr. Paxton’s clinical expertise includes patient safety, motion management, radiosurgery, and proton therapy. Benjamin Waghorn, PhD, DABR is the Director of Clinical Physics at Vision RT. Dr. Waghorn’s research interests include intensity modulated radiation therapy, motion management, and surface image guidance systems. Todd Pawlicki, PhD, DABR, FAAPM, FASTRO, is Professor and Vice-Chair for Medical Physics in the Department of Radiation Medicine and Applied Sciences at the University of California, San Diego. Dr. Pawlicki has published extensively on quality and safety in radiation therapy. He has served on the Board of Directors for the American Society for Radiology Oncology (ASTRO) and the American Association of Physicists in Medicine (AAPM). |
can breast cancer be treated with proton therapy: Radiation Therapy Techniques and Treatment Planning for Breast Cancer Jennifer R. Bellon, Julia S. Wong, Shannon M. MacDonald, Alice Y. Ho, 2016-09-15 This book addresses the day-to-day treatment planning issues that radiation oncologists are likely to encounter during the treatment of breast cancer patients and provides numerous practical “tips” that will assist in navigation of the treatment planning process, from delineation of the tumor boundaries to discrimination of adjacent normal tissues and critical structures at risk of radiation injury. Differences in target delineation and treatment planning according to technique are emphasized, with coverage of conventional radiation therapy and advanced techniques including cardiac-sparing approaches, e.g., using active breathing control, intensity-modulated radiation therapy, proton beam therapy, and electron beam therapy post mastectomy. Individual chapters also focus on radiation setup and verification techniques and radiation treatment planning systems. The book, which is part of the Springer series Practical Guides in Radiation Oncology, is designed for hands-on use by radiation oncology residents/fellows in training and practicing radiation oncologists. |
can breast cancer be treated with proton therapy: Accelerated Partial Breast Irradiation David E. Wazer, Douglas W. Arthur, Frank Vicini, 2009-08-11 Accelerated partial breast irradiation (APBI) is being rapidly introduced into the clinical management of early breast cancer. APBI, in fact, encompasses a number of different techniques and approaches that include brachytherapy, intraoperative, and external beam techniques. There is currently no single source that describes these techniques and their clinical implementation. This text is a concise handbook designed to assist the clinician in the implementation of APBI. This includes a review of the principles that underlie APBI, a practical and detailed description of each technique for APBI, a review of current clinical results of APBI, and a review of the incidence and management of treatment related complications. |
can breast cancer be treated with proton therapy: Stereotactic Body Radiation Therapy Simon S. Lo, Bin S. Teh, Jiade J. Lu, Tracey E. Schefter, 2012-08-28 Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists. |
can breast cancer be treated with proton therapy: Proton and Carbon Ion Therapy C-M Charlie Ma, Tony Lomax, 2012-10-09 Proton and Carbon Ion Therapy is an up-to-date guide to using proton and carbon ion therapy in modern cancer treatment. The book covers the physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, and treatment delivery systems. It gives practical guidance on patient setup, target localization, and treatment planning for clinical proton and carbon ion therapy. The text also offers detailed reports on the treatment of pediatric cancers, lymphomas, and various other cancers. After an overview, the book focuses on the fundamental aspects of proton and carbon ion therapy equipment, including accelerators, gantries, and delivery systems. It then discusses dosimetry, biology, imaging, and treatment planning basics and provides clinical guidelines on the use of proton and carbon ion therapy for the treatment of specific cancers. Suitable for anyone involved with medical physics and radiation therapy, this book offers a balanced and critical assessment of state-of-the-art technologies, major challenges, and the future outlook of proton and carbon ion therapy. It presents a thorough introduction for those new to the field while providing a helpful, up-to-date reference for readers already using the therapy in clinical settings. |
can breast cancer be treated with proton therapy: Intraoperative Radiotherapy for Breast Cancer Frederik Wenz, Uta Kraus-Tiefenbacher, 2011 |
can breast cancer be treated with proton therapy: Practical Radiation Oncology Supriya Mallick, Goura K. Rath, Rony Benson, 2019-11-25 This book addresses the most relevant aspects of radiation oncology in terms of technical integrity, dose parameters, machine and software specifications, as well as regulatory requirements. Radiation oncology is a unique field that combines physics and biology. As a result, it has not only a clinical aspect, but also a physics aspect and biology aspect, all three of which are inter-related and critical to optimal radiation treatment planning. In addition, radiation oncology involves a host of machines/software. One needs to have a firm command of these machines and their specifications to deliver comprehensive treatment. However, this information is not readily available, which poses serious challenges for students learning the planning aspect of radiation therapy. In response, this book compiles these relevant aspects in a single source. Radiation oncology is a dynamic field, and is continuously evolving. However, tracking down the latest findings is both difficult and time-consuming. Consequently, the book also comprehensively covers the most important trials. Offering an essential ready reference work, it represents a value asset for all radiation oncology practitioners, trainees and students. |
can breast cancer be treated with proton therapy: Target Volume Delineation and Treatment Planning for Particle Therapy Nancy Y. Lee, Jonathan E. Leeman, Oren Cahlon, Kevin Sine, Guoliang Jiang, Jiade J. Lu, Stefan Both, 2017-12-19 This handbook is designed to enable radiation oncologists to treat patients appropriately and confidently by means of particle therapy. The orientation and purpose are entirely practical, in that the focus is on the physics essentials of delivery and treatment planning , illustration of the clinical target volume (CTV) and associated treatment planning for each major malignancy when using particle therapy, proton therapy in particular. Disease-specific chapters provide guidelines and concise knowledge on CTV selection and delineation and identify aspects that require the exercise of caution during treatment planning. The treatment planning techniques unique to proton therapy for each disease site are clearly described, covering beam orientation, matching/patching field techniques, robustness planning, robustness plan evaluation, etc. The published data on the use of particle therapy for a given disease site are also concisely reported. In addition to fully meeting the needs of radiation oncologists, this know why and “know how” guide to particle therapy will be valuable for medical physicists, dosimetrists, and radiation therapists. |
can breast cancer be treated with proton therapy: Proton Therapy Thomas J. FitzGerald, Maryann Bishop-Jodoin, 2021-08-18 Over the past twenty-five years, proton therapy has become more prominent worldwide. It is an important component of clinical radiation therapy for both adult and pediatric clinical care. Due to the inherent ability of protons to spare normal tissue, protons will continue to develop and become increasingly important in radiation oncology. As such, Proton Therapy - Current Status and Future Directions reviews many aspects of proton care including the application of protons in modern clinical trials. It also reviews problems associated with the migration of proton care worldwide and examines the future direction of proton care. This project was created by colleagues at IntechOpen and was carefully managed by Romina Rovan. It has been a privilege to help coordinate the text and chapters designed to acknowledge the history, footprint, and growing interest of proton care worldwide. Proton management is now embedded in the clinical trials process. In pediatric care, proton delivery is embedded with photons for the management of pediatric malignancies and adult groups have initiated proton-specific clinical trials. A proton registry has been established and outcomes are under evaluation. Due to the inherent ability of protons to spare normal tissue, protons will continue to develop and become increasingly important in radiation oncology. |
can breast cancer be treated with proton therapy: Encyclopedia of Radiation Oncology Luther W. Brady, Theodore Yaeger, 2012-09-15 This comprehensive encyclopedia, comprising a wide range of entries written by leading experts, provides detailed information on radiation oncology, including the most recent developments in the field. It will be of particular value for basic and clinical scientists in academia, practice, and industry and will also be of benefit to those in related fields, students, teachers, and interested laypersons. |
can breast cancer be treated with proton therapy: Radiotherapy for Hodgkin Lymphoma Lena Specht, Joachim Yahalom, 2010-09-10 This book deals in detail with all aspects of the best practice in modern radiotherapy for Hodgkin lymphoma. It provides the background and rationale for the inclusion of radiotherapy in today’s combined-modality approach, including special clinical situations such as Hodgkin lymphoma in children, in the pregnant patient, and in the elderly. Radiotherapy planning using state-of-the-art imaging, target definition, planning software, and treatment equipment is expounded in detail. Acute and long-term side effects of radiotherapy are analyzed, and the implications for modern radiotherapy approaches in Hodgkin lymphoma are explained. |
can breast cancer be treated with proton therapy: Clinical Radiation Oncology Leonard L. Gunderson, MD, MS, FASTRO, Joel E. Tepper, MD, 2015-08-26 Perfect for radiation oncology physicians and residents needing a multidisciplinary, treatment-focused resource, this updated edition continues to provide the latest knowledge in this consistently growing field. Not only will you broaden your understanding of the basic biology of disease processes, you'll also access updated treatment algorithms, information on techniques, and state-of-the-art modalities. The consistent and concise format provides just the right amount of information, making Clinical Radiation Oncology a welcome resource for use by the entire radiation oncology team. Content is templated and divided into three sections -- Scientific Foundations of Radiation Oncology, Techniques and Modalities, and Disease Sites - for quick access to information. Disease Sites chapters summarize the most important issues on the opening page and include a full-color format, liberal use of tables and figures, a closing section with a discussion of controversies and problems, and a treatment algorithm that reflects the treatment approach of the authors. Chapters have been edited for scientific accuracy, organization, format, and adequacy of outcome data (such as disease control, survival, and treatment tolerance). Allows you to examine the therapeutic management of specific disease sites based on single-modality and combined-modality approaches. Features an emphasis on providing workup and treatment algorithms for each major disease process, as well as the coverage of molecular biology and its relevance to individual diseases. Two new chapters provide an increased emphasis on stereotactic radiosurgery (SRS) and stereotactic body irradiation (SBRT). New Associate Editor, Dr. Andrea Ng, offers her unique perspectives to the Lymphoma and Hematologic Malignancies section. Key Points are summarized at the beginning of each disease-site chapter, mirroring the template headings and highlighting essential information and outcomes. Treatment algorithms and techniques, together with discussions of controversies and problems, reflect the treatment approaches employed by the authors. Disease Site Overviews allow each section editor to give a unique perspective on important issues, while online updates to Disease Site chapters ensure your knowledge is current. Disease Site chapters feature updated information on disease management and outcomes. Four videos accessible on Expert Consult include Intraoperative Irradiation, Prostate Brachytherapy, Penile Brachytherapy, and Ocular Melanoma. Thirty all-new anatomy drawings increase your visual understanding. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices. |
can breast cancer be treated with proton therapy: Image-Guided IMRT Thomas Bortfeld, Rupert Schmidt-Ullrich, Wilfried De Neve, David E. Wazer, 2006-05-28 Intensity-modulated radiation therapy (IMRT), one of the most important developments in radiation oncology in the past 25 years, involves technology to deliver radiation to tumors in the right location, quantity and time. Unavoidable irradiation of surrounding normal tissues is distributed so as to preserve their function. The achievements and future directions in the field are grouped in the three sections of the book, each suitable for supporting a teaching course. Part 1 contains topical reviews of the basic principles of IMRT, part 2 describes advanced techniques such as image-guided and biologically based approaches, and part 3 focuses on investigation of IMRT to improve outcome at various cancer sites. |
can breast cancer be treated with proton therapy: Prescription for Proton Radiation Denise Durgin, 2021-11-30 |
can breast cancer be treated with proton therapy: Adjuvant Therapy for Breast Cancer Monica Castiglione, Martine J. Piccart, 2009-07-11 Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable. |
can breast cancer be treated with proton therapy: Handbook of Treatment Planning, 2nd Ed Gregory M. M. Videtic, Neil Woody, Andrew D. Vassil, 2014-08-14 This is a highly practical resource about the specific technical aspects of delivering radiation treatment. Pocket-sized and well organized for ease of use, the book is designed to lead radiation oncology trainees and residents step by step through the basics of radiotherapy planning and delivery for all major malignancies. This second edition retains the valued features of the first edition-comprehensive yet concise, practical, evidence-based-while incorporating recent advances in the field. This includes expanded and updated discussions of SBRT for prostate and GI tumors, intraoperative. |
can breast cancer be treated with proton therapy: Proton Therapy Steven J Frank, X. Ronald Zhu, 2020-05-18 As proton therapy treatment centers become smaller and more cost-effective, education and training for today’s multi-disciplinary oncology teams are more important than ever before. This state-of-the-art reference brings you fully up to date with all aspects of proton therapy, with guidance you can trust from MD Anderson Cancer Center, the largest and most experienced proton therapy center in the world. Led by Drs. Steven J. Frank and W. Ronald Zhu, Proton Therapy provides a unique opportunity to benefit from the unsurpassed knowledge and expertise of an esteemed team of leaders in the field. Covers all cancers for which proton therapy is used most often, including prostate, head and neck, pediatrics, central nervous system, gastrointestinal, sarcomas, lungs, breast, lymphomas, and gynecologic cancers. Provides up-to-date information on radiobiology, treatment planning and quality assurance, indications for proton therapy, management approaches, and outcomes after proton therapy by disease site. Discusses technologic advances such as spot scanning and treatment planning systems for the management of solid tumors; radiobiology of proton therapy, including DNA damage and repair mechanisms and acute and late effects on normal tissues; and multifield optimized intensity-modulated proton therapy (MFO-IMPT) for optimizing the distribution of linear energy transfer (LET) of proton beams within target volumes and away from critical normal structures. Includes a special section on head and neck cases in the e-book that photographically illustrates the full cycle of proton therapy care. |
can breast cancer be treated with proton therapy: Fruits, Vegetables, and Herbs Ronald Ross Watson, Victor R Preedy, 2016-04-23 Fruits, Vegetables, and Herbs: Bioactive Foods in Health Promotion brings together experts from around the world working on the cutting edge of research on fruit, vegetables, and herbs in health promotion. Offering a timely, concise, scientific appraisal of the efficacy of key foods to prevent disease and improve the quality of life, Fruits, Vegetables, and Herbs: Bioactive Foods in Health Promotion provides valuable evidence-based conclusions and recommendations. This reference text will encourage further research on the potential benefits of fruits and vegetables in health and disease prevention, providing a basis for possible dietary modifications by the government and the public. - Provides insight on bioactive constituents found in fruits and vegetables that can be further studied to improve health and disease resistance or incorporated into other food products and used as alternative medicines and dietary supplements - Includes valuable information on how fruits are important sources of bioflavonoids and nonnutritive bioactives that modify body functions - Offers a conclusion or summary of evidence at the end of each chapter to enhance understanding of new approaches in the field |
can breast cancer be treated with proton therapy: Initial National Priorities for Comparative Effectiveness Research Institute of Medicine, Board on Health Care Services, Committee on Comparative Effectiveness Research Prioritization, 2009-11-14 Clinical research presents health care providers with information on the natural history and clinical presentations of disease as well as diagnostic and treatment options. In today's healthcare system, patients, physicians, clinicians and family caregivers often lack the sufficient scientific data and evidence they need to determine the best course of treatment for the patients' medical conditions. Initial National Priorities for Comparative Effectiveness Research(CER) is designed to fill this knowledge gap by assisting patients and healthcare providers across diverse settings in making more informed decisions. In this 2009 report, the Institute of Medicine's Committee on Comparative Effectiveness Research Prioritization establishes a working definition of CER, develops a priority list of research topics, and identifies the necessary requirements to support a robust and sustainable CER enterprise. As part of the 2009 American Recovery and Reinvestment Act, Congress appropriated $1.1 billion in federal support of CER, reflecting legislators' belief that better decisions about the use of health care could improve the public's health and reduce the cost of care. The Committee on Comparative Effectiveness Research Prioritization was successful in preparing a list 100 top priority CER topics and 10 recommendations for best practices in the field. |
can breast cancer be treated with proton therapy: Short Course Breast Radiotherapy Douglas W Arthur, Frank A. Vicini, David E. Wazer, Atif J. Khan, 2015-12-31 This comprehensive handbook on the implementation of short course radiotherapy for the treatment of breast cancer is intended as an up-to-date resource for the clinician. The book opens with a series of chapters on underlying principles and diverse relevant topics, including pathologic anatomy of early-stage breast cancer, radiobiology of accelerated breast irradiation, quality assurance and radiation safety, surgical considerations in partial breast irradiation, and impact of oncoplastic surgery on adjuvant radiotherapy. Individual sections are then devoted to hypofractionated whole breast radiotherapy, accelerated partial breast irradiation, and intraoperative radiotherapy. Each section includes details of patient selection, physics, techniques, data, and toxicity. The reader is provided with clear guidance on the appropriate use of accelerated forms of adjuvant radiotherapy for treatment of early-stage breast cancer and on various emerging treatment approaches. |
can breast cancer be treated with proton therapy: Proton Therapy Physics Harald Paganetti, 2016-04-19 Proton Therapy Physics goes beyond current books on proton therapy to provide an in-depth overview of the physics aspects of this radiation therapy modality, eliminating the need to dig through information scattered in the medical physics literature. After tracing the history of proton therapy, the book summarizes the atomic and nuclear physics background necessary for understanding proton interactions with tissue. It describes the physics of proton accelerators, the parameters of clinical proton beams, and the mechanisms to generate a conformal dose distribution in a patient. The text then covers detector systems and measuring techniques for reference dosimetry, outlines basic quality assurance and commissioning guidelines, and gives examples of Monte Carlo simulations in proton therapy. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. It also examines computerized treatment plan optimization, methods for in vivo dose or beam range verification, the safety of patients and operating personnel, and the biological implications of using protons from a physics perspective. The final chapter illustrates the use of risk models for common tissue complications in treatment optimization. Along with exploring quality assurance issues and biological considerations, this practical guide collects the latest clinical studies on the use of protons in treatment planning and radiation monitoring. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, the book helps readers understand the uncertainties and limitations of precisely shaped dose distribution. |
can breast cancer be treated with proton therapy: New Technologies in Radiation Oncology Wolfgang C. Schlegel, Thomas Bortfeld, Anca Ligia Grosu, 2006-01-27 - Summarizes the state of the art in the most relevant areas of medical physics and engineering applied to radiation oncology - Covers all relevant areas of the subject in detail, including 3D imaging and image processing, 3D treatment planning, modern treatment techniques, patient positioning, and aspects of verification and quality assurance - Conveys information in a readily understandable way that will appeal to professionals and students with a medical background as well as to newcomers to radiation oncology from the field of physics |
can breast cancer be treated with proton therapy: Intensity-Modulated Radiation Therapy S. Webb, 2015-05-06 Clinical conformal radiotherapy is the holy grail of radiation treatment and is now becoming a reality through the combined efforts of physical scientists and engineers, who have improved the physical basis of radiotherapy, and the interest and concern of imaginative radiotherapists and radiographers. Intensity-Modulated Radiation Therapy de |
can breast cancer be treated with proton therapy: The Breast K. I. Bland, Edward M. Copeland, 2009 Offering the most comprehensive, up-to-date information on the diagnosis and management of, and rehabilitation following, surgery for benign and malignant diseases of the breast, this surgical reference is now in a new edition available in both print and online for easy, convenient access to the absolute latest advances. |
can breast cancer be treated with proton therapy: Saving Women's Lives National Research Council, Institute of Medicine, Policy and Global Affairs, Board on Science, Technology, and Economic Policy, National Cancer Policy Board, Committee on New Approaches to Early Detection and Diagnosis of Breast Cancer, 2005-03-18 The outlook for women with breast cancer has improved in recent years. Due to the combination of improved treatments and the benefits of mammography screening, breast cancer mortality has decreased steadily since 1989. Yet breast cancer remains a major problem, second only to lung cancer as a leading cause of death from cancer for women. To date, no means to prevent breast cancer has been discovered and experience has shown that treatments are most effective when a cancer is detected early, before it has spread to other tissues. These two facts suggest that the most effective way to continue reducing the death toll from breast cancer is improved early detection and diagnosis. Building on the 2001 report Mammography and Beyond, this new book not only examines ways to improve implementation and use of new and current breast cancer detection technologies but also evaluates the need to develop tools that identify women who would benefit most from early detection screening. Saving Women's Lives: Strategies for Improving Breast Cancer Detection and Diagnosis encourages more research that integrates the development, validation, and analysis of the types of technologies in clinical practice that promote improved risk identification techniques. In this way, methods and technologies that improve detection and diagnosis can be more effectively developed and implemented. |
can breast cancer be treated with proton therapy: Re-Irradiation: New Frontiers Carsten Nieder, Johannes Langendijk, 2016-10-25 This book, now in its second edition, provides a comprehensive overview of current re-irradiation strategies, with detailed discussion of re-irradiation methods, technical aspects, the role of combined therapy with anticancer drugs and hyperthermia, and normal tissue tolerance. In addition, disease specific chapters document recent clinical results and future research directions. All chapters from the first edition have been revised and updated to take account of the latest developments and research findings, including those from prospective studies. Due attention is paid to the exciting developments in the fields of proton irradiation and frameless image-guided ablative radiotherapy. The book documents fully how refined combined modality approaches and significant technical advances in radiation treatment planning and delivery have facilitated the re-irradiation of previously exposed volumes, allowing both palliative and curative approaches to be pursued at various disease sites. Professionals involved in radiation treatment planning and multimodal oncology treatment will find it to be an invaluable aid in understanding the benefits and limitations of re-irradiation and in designing prospective trials. |
can breast cancer be treated with proton therapy: Advances in Particle Therapy Manjit Dosanjh, Jacques Bernier, 2018-05-11 Hadron therapy is a groundbreaking new method of treating cancer. Boasting greater precision than other therapies, this therapy is now utilised in many clinical settings and the field is growing. More than 50 medical facilities currently perform (or are planned to perform) this treatment, with this number set to double by 2020. This new text covers the most recent advances in hadron therapy, exploring the physics, technology, biology, diagnosis, clinical applications, and economics behind the therapy. Providing essential and up-to-date information on recent developments in the field, this book will be of interest to current and aspiring specialists from a wide range of backgrounds. Features: Multidisciplinary approach: explores the physics, IT (big data), biology, clinical applications from imaging to treatment, clinical trials, and economics associated with hadron therapy Contains the latest research and developments in this rapidly evolving field, and integrates them into the current global challenges for radiation therapy Edited by recognised leaders in the field, including the co-ordinator of ENLIGHT (the European Network for Light Ion Hadron Therapy), with chapter contributions from international leading experts in the field |
can breast cancer be treated with proton therapy: A National Cancer Clinical Trials System for the 21st Century Institute of Medicine, Board on Health Care Services, Committee on Cancer Clinical Trials and the NCI Cooperative Group Program, 2010-07-08 The National Cancer Institute's (NCI) Clinical Trials Cooperative Group Program has played a key role in developing new and improved cancer therapies. However, the program is falling short of its potential, and the IOM recommends changes that aim to transform the Cooperative Group Program into a dynamic system that efficiently responds to emerging scientific knowledge; involves broad cooperation of stakeholders; and leverages evolving technologies to provide high-quality, practice-changing research. |
can breast cancer be treated with proton therapy: Overtreated Shannon Brownlee, 2010-06-25 Our health care is staggeringly expensive, yet one in six Americans has no health insurance. We have some of the most skilled physicians in the world, yet one hundred thousand patients die each year from medical errors. In this gripping, eye-opening book, award-winning journalist Shannon Brownlee takes readers inside the hospital to dismantle some of our most venerated myths about American medicine. Brownlee dissects what she calls the medical-industrial complex and lays bare the backward economic incentives embedded in our system, revealing a stunning portrait of the care we now receive. Nevertheless, Overtreated ultimately conveys a message of hope by reframing the debate over health care reform. It offers a way to control costs and cover the uninsured, while simultaneously improving the quality of American medicine. Shannon Brownlee's humane, intelligent, and penetrating analysis empowers readers to avoid the perils of overtreatment, as well as pointing the way to better health care for everyone. |
can breast cancer be treated with proton therapy: Image-Guided Cancer Therapy Damian E. Dupuy, Yuman Fong, William N. McMullen, 2013-08-06 Image-Guided Cancer Therapy: A Multidisciplinary Approach provides clinicians with in-depth coverage of the growing, dynamic field of interventional oncology. Combining the knowledge of expert editors and authors into one powerhouse reference, this book looks at tumor ablation, HIFU, embolic therapies, emerging technologies, and radiation therapy throughout the body (liver, bone, breast, gynecologic and prostate cancers, to name just a few) , and includes discussion of different imaging modalities. In the words of Peter Mueller, MD, author of the book’s Foreword: “... The senior authors are all world renowned experts in interventional oncology, which is another example of the high quality authorship and experience that is brought to this book. The later chapters discuss therapies that are simply not covered in any other source. Everyone who is doing or wants to do ablation therapies and interventional oncology will face a time when they will be asked to use their expertise in less used and less investigated areas. There is nowhere else where the reader can get information on the prostate, breast, and gynecologic areas, and especially pediatrics....This book is an outstanding contribution to the literature and will become a ‘must read’ for all physicians who are interested in Interventional Oncology.” |
can breast cancer be treated with proton therapy: Pediatric Radiation Oncology Edward C. Halperin, Louis S. Constine, Nancy J. Tarbell, Larry E. Kun, 2012-03-28 Established since 1986 as the definitive text and reference on use of radiation therapy for childhood cancer, Pediatric Radiation Oncology is now in its thoroughly revised and updated Fifth Edition. This edition reviews all significant recent clinical trials—including, for the first time, significant European clinical trials—and provides increased coverage of international and Third World issues. The latest cancer staging guidelines are included. New chapters cover psychosocial aspects of radiotherapy for the child and family and medical management of pain, nausea, nutritional problems, and blood count depression in the child with cancer. This edition also has full-color illustrations throughout. A companion website includes the full text and an image bank. |
can breast cancer be treated with proton therapy: Cancer Care for the Whole Patient Institute of Medicine, Board on Health Care Services, Committee on Psychosocial Services to Cancer Patients/Families in a Community Setting, 2008-03-19 Cancer care today often provides state-of-the-science biomedical treatment, but fails to address the psychological and social (psychosocial) problems associated with the illness. This failure can compromise the effectiveness of health care and thereby adversely affect the health of cancer patients. Psychological and social problems created or exacerbated by cancer-including depression and other emotional problems; lack of information or skills needed to manage the illness; lack of transportation or other resources; and disruptions in work, school, and family life-cause additional suffering, weaken adherence to prescribed treatments, and threaten patients' return to health. Today, it is not possible to deliver high-quality cancer care without using existing approaches, tools, and resources to address patients' psychosocial health needs. All patients with cancer and their families should expect and receive cancer care that ensures the provision of appropriate psychosocial health services. Cancer Care for the Whole Patient recommends actions that oncology providers, health policy makers, educators, health insurers, health planners, researchers and research sponsors, and consumer advocates should undertake to ensure that this standard is met. |
can breast cancer be treated with proton therapy: The Prime Cause of Cancer Otto Warburg, Trung Nguyen, 2015-12-02 This is book 2 of 5 of the “Understand Cancer” series. It is based on the best-available science. The SECONDARY causes of cancer were discussed in book one. This book continues from book one and discusses the PRIME cause of cancer as discovered by Nobel Prize Laureate Dr. Otto Warburg—considered by many as the founder of modern biochemistry. “There are prime and secondary causes of diseases. For example, the prime cause of the plague is the plague bacillus, but secondary causes of the plague are filth, rats, and the fleas that transfer the plague bacillus from rats to man. By a prime cause of a disease I mean one that is found in every case of the disease...Cancer, above all other diseases, has countless secondary causes. But, even for cancer, there is only one prime cause. Summarized in a few words, the prime cause of cancer is the replacement of the respiration of oxygen in normal body cells by a fermentation of sugar. All normal body cells meet their energy needs by respiration of oxygen, whereas cancer cells meet their energy needs in great part by fermentation. All normal body cells are thus obligate aerobes, whereas all cancer cells are partial anaerobes. From the standpoint of the physics and chemistry of life this difference between normal and cancer cells is so great that one can scarcely picture a greater difference. Oxygen gas, the donor of energy in plants and animals is dethroned in the cancer cells and replaced by an energy yielding reaction of the lowest living forms, namely, a fermentation of glucose.” —Dr. Otto Warburg |
can breast cancer be treated with proton therapy: Diagnosing and Treating Adult Cancers and Associated Impairments National Academies Of Sciences Engineeri, National Academies of Sciences Engineering and Medicine, Health And Medicine Division, Board On Health Care Services, Committee on Diagnosing and Treating Adult Cancers, 2021-11-10 Cancer is the second leading cause of death among adults in the United States after heart disease. However, improvements in cancer treatment and earlier detection are leading to growing numbers of cancer survivors. As the number of cancer survivors grows, there is increased interest in how cancer and its treatments may affect a person's ability to work, whether the person has maintained employment throughout the treatment or is returning to work at a previous, current, or new place of employment. Cancer-related impairments and resulting functional limitations may or may not lead to disability as defined by the U.S. Social Security Administration (SSA), however, adults surviving cancer who are unable to work because of cancer-related impairments and functional limitations may apply for disability benefits from SSA. At the request of SSA, Diagnosing and Treating Adult Cancers and Associated Impairments provides background information on breast cancer, lung cancer, and selected other cancers to assist SSA in its review of the listing of impairments for disability assessments. This report addresses several specific topics, including determining the latest standards of care as well as new technologies for understanding disease processes, treatment modalities, and the effect of cancer on a person's health and functioning, in order to inform SSA's evaluation of disability claims for adults with cancer. |
can breast cancer be treated with proton therapy: Cognition and Cancer Christina A. Meyers, James R. Perry, 2012-12-13 This book is a unique resource on the influence cancer and cancer treatments have on cognition. The majority of cancer patients on active treatment experience cognitive impairments often referred to as 'chemobrain' or 'chemofog'. In addition, patients with primary or metastatic tumors of the brain often experience direct neurologic symptoms. This book helps health care professionals working with cancer patients who experience cognitive changes and provides practical information to help improve care by reviewing and describing brain-behavior relationships; research-based evidence on cognitive changes that occur with various cancers and cancer treatments; assessment techniques, including neurocognitive assessment and neuroimaging techniques; and intervention strategies for affected patients. In short, it will explain how to identify, assess and treat these conditions. |
can breast cancer be treated with proton therapy: Cummings Otolaryngology--head & Neck Surgery Paul W. Flint, Bruce H. Haughey, Valerie J. Lund, John K. Niparko, K. Thomas Robbins, J. Regan Thomas, Marci M. Lesperance, 2015 2015 BMA Medical Book Awards Highly Commended in Surgical Specialties Category! Now in its 6th edition, Cummings Otolaryngology remains the world's most detailed and trusted source for superb guidance on all facets of head and neck surgery. Completely updated with the latest minimally invasive procedures, new clinical photographs, line drawings, and new surgical videos, this latest edition equips you to implement all the newest discoveries, techniques, and technologies that are shaping patient outcomes. Be certain with expert, dependable, accurate answers for every stage of your career from the most comprehensive, multi-disciplinary text in the field! Overcome virtually any clinical challenge with detailed, expert coverage of every area of head and neck surgery, authored by hundreds of leading luminaries in the field. Experience clinical scenarios with vivid clarity through a heavily illustrated, full-color format which includes approximately 3,200 images and over 40 high quality procedural videos. Get truly diverse perspectives and worldwide best practices from a multi-disciplinary team of contributors and editors comprised of the world's leading experts. Glean all essential, up-to-date, need-to-know information. All chapters have been meticulously updated; several extensively revised with new images, references, and content. Stay at the forefront of your field with the most updated information on minimally-invasive surgical approaches to the entire skull base, vestibular implants and vestibular management involving intratympanic and physical therapy-based approaches, radiosurgical treatment of posterior fossa and skull base neoplasms, and intraoperative monitoring of cranial nerve and CNS function. Apply the latest treatment options in pediatric care with new chapters on pediatric sleep disorders, pediatric infectious disease, and evaluation and management of the infant airway. Find what you need faster through a streamlined format, reorganized chapters, and a color design that expedites reference. Manage many of the most common disorders with treatment options derived from their genetic basis. Assess real-world effectiveness and costs associated with emergent technologies and surgical approaches introduced to OHNS over the past 10 years. Incorporate recent findings about endoscopic, microscopic, laser, surgically-implantable, radiosurgical, neurophysiological monitoring, MR- and CT-imaging, and other timely topics that now define contemporary operative OHNS. Take it with you anywhere! With Expert Consult, you'll have access the full text, video clips, and more online, and as an eBook - at no additional cost! |
can breast cancer be treated with proton therapy: NCCN Guidelines for Patients® Invasive Breast Cancer National Comprehensive Cancer Network® (NCCN®), 2023-04-18 [OFFICIAL CURRENT VERSION] From the National Comprehensive Cancer Network (NCCN) comes this essential guide to Invasive Breast Cancer. Based on clinical treatment guidelines used by doctors and oncology professionals around the world, these NCCN Guidelines for Patients help patients and caregivers talk with their doctors and make treatment decisions. Topics include: Breast cancer basics, Testing for breast cancer, Breast cancer staging, Treating breast cancer, Surgery first, Preop treatment first, The breast after surgery, Recurrence, Making treatment decisions, Words to know, NCCN Contributors, NCCN Cancer Centers, Index |
can breast cancer be treated with proton therapy: Contrast-Enhanced Digital Mammography (CEDM) Jacopo Nori, Maninderpal Kaur, 2018-10-09 This book offers a comprehensive, practical resource entirely devoted to Contrast-Enhanced Digital Mammography (CEDM), a state-of-the-art technique that has emerged as a valuable addition to conventional imaging modalities in the detection of primary and recurrent breast cancer, and as an important preoperative staging tool for women with breast cancer. CEDM is a relatively new breast imaging technique based on dual energy acquisition, combining mammography with iodine-based contrast agents to display contrast uptake in breast lesions. It improves the sensitivity and specificity of breast cancer detection by providing higher foci to breast-gland contrast and better lesion delineation than digital mammography. Preliminary results suggest that CEDM is comparable to breast MRI for evaluating the extent and size of lesions and detecting multifocal lesions, and thus has the potential to become a readily available, fast and cost-effective examination. With a focus on the basic imaging principles of CEDM, this book takes a practical approach to breast imaging. Drawing on the editors’ and authors’ practical experience, it guides the reader through the basics of CEDM, making it especially accessible for beginners. By presenting the key aspects of CEDM in a straightforward manner and supported by clear images, the book represents a valuable guide for all practicing radiologists, in particular those who perform breast imaging and have recently incorporated or plan to incorporate CEDM into their diagnostic arsenal. |
can breast cancer be treated with proton therapy: External Field and Radiation Stimulated Breast Cancer Nanotheranostics Nanasaheb D. Thorat, Joanna Bauer, 2019-09-26 Nano drug-delivery systems responding to cellular local stimuli, such as pH, temperature and reductive agent's activation, i.e. enzymes, could effectively provide passive-mode desirable release but fail in disease treatment following the biological rhythms of brain tumor. This book is a compilation of research development lead by expert researchers and it establishes a single reference module. It addresses, for the first time, all translational aspects and clinical perspectives of physically stimulated breast-cancer nanotheranostics from a wide-ranging and multidisciplinary perception providing unrivalled and comprehensive knowledge in the field. |
can breast cancer be treated with proton therapy: The Cell Cycle and Cancer Renato Baserga, 1971 |
A Guide to Proton Therapy for Patients with Breast Cancers
Many patients with breast cancer are good candidates for proton therapy. To better understand the use of proton therapy in your treatment, call to schedule a consultation with a radiation …
Proton Therapy for Breast Cancer: A Consensus Statement …
Proton therapy (PT) for breast cancer has seen rapid growth because of improved access with expansion of proton centers across the globe, technical advances, and an increasing rec …
Types of Cancers Treated with PROTON THERAPY
Proton therapy may be a more precise radiation option for treatment of gynecologic cancers to help protect the function of important nearby organs like the bowels,
Proton therapy for breast cancer - Medical Xpress
Proton therapy is not offered for the majority of patients with breast cancer. However, there are some circumstances where there may be a benefit.
NHS England Evidence review: Proton beam therapy for …
• Proton beam therapy (PBT) is an alternative to conventional photon radiotherapy. • Photons deliver a continuous energy beam which can cause damage to surrounding healthy tissue …
Proton therapy for breast cancer: Reducing toxicity - Wiley …
Proton therapy (PT) is a new and rapidly developing radiotherapy method. In comparison with con-ventional photon therapy, PT offers the benefits of decreased radiation toxicity and …
Planning and Treatment Recommendations for Breast Proton …
Despite the growing use of proton therapy for breast cancer, there are few recommendations for planning and treatment.
Proton therapy for the treatment of inflammatory breast cancer
Intensity modulated proton therapy (IMPT) is an attractive emerging modality for breast cancer due to unique physical prop- erties with rapid dose fall-off at the proton Bragg Peak [18,19].
Proton Therapy for Breast cancer
The good news is that with proton therapy, radiation can be stopped inside the tumor bed and breast tissue only, reducing or eliminating radiation dose to the heart and other critical structures.
Proton therapy—frequently asked questions. - MedStar Health
What types of cancers or tumors can proton therapy treat? Proton therapy can treat cancer anywhere in the body, including: • Brain tumors • Breast cancer • Gastrointestinal (GI) cancers …
Proton therapy: Precise, proven treatment for breast cancer
“Proton therapy was the best treatment to take care of my breast cancer with less risk to my heart, my lungs, and my future.” —ProCure patient, breast cancer
Proton Therapy FAQ - Scripps Health
Specific tumor sites well-suited for proton therapy include breast, lung, prostate, spine, head, neck, brain, gastrointestinal tract and central nervous system, among others. Proton is also …
Proton Therapy for Breast Cancer: Progress & Pitfalls
Proton therapy is under investigation for early stage and locally advanced breast cancer. Due to unique physical properties, proton therapy reduces the dose to the heart, lungs, skin, muscle, …
Proton Therapy for Patients with Cancer - Northwestern …
Although tumors can be treated with surgery, chemotherapy and standard X-ray radiation, proton therapy can be particularly beneficial for patients with certain types of cancer and some non …
Proton Therapy in Breast Cancer: A Review of Volume 23: 1-16 …
Proton radiotherapy may be a compelling technical option for the treatment of breast cancer due to its unique physical property known as the “Bragg peak. This feature offers distinct …
COMMON QUESTIONS ABOUT PROTON THERAPY - Texas …
Proton therapy is a highly-targeted form of radiation therapy that is effective for cancerous tumors throughout the body. This cancer-fighting technology is non-invasive and may reduce side …
Treating recurrent metastatic breast cancer to the skin with …
breast cancer, particularly when recurrent disease occurs near previously irradiated tissues. This case study demonstrates the dosimetric benefits of proton therapy in patients with metastatic …
Proton Reirradiation for Locoregionally Recurrent Breast Cancer
Proton therapy is recommended by the American Society for Radiation Oncology in cases where reirrradiation is needed; however, data are limited. We present the toxicity and outcomes after …
Proton therapy for early breast cancer patients in the DBCG …
In this study, we present the treatment strategy at the Danish Centre for Particle Therapy (DCPT) for patients referred to proton therapy based on the DBCG proton trial selection criteria.
The potential of proton beam radiation therapy in breast cancer
In primary breast cancer, it is estimated that about 300 of the annually 3425 irradiated patients can potentially be candidates for proton beam therapy to reduce late toxicity, mainly from the …
A Guide to Proton Therapy for Patients with Breast Cancers
Many patients with breast cancer are good candidates for proton therapy. To better understand the use of proton therapy in your treatment, call to schedule a consultation with a radiation …
Proton Therapy for Breast Cancer: A Consensus Statement …
Proton therapy (PT) for breast cancer has seen rapid growth because of improved access with expansion of proton centers across the globe, technical advances, and an increasing rec …
Types of Cancers Treated with PROTON THERAPY
Proton therapy may be a more precise radiation option for treatment of gynecologic cancers to help protect the function of important nearby organs like the bowels,
Proton therapy for breast cancer - Medical Xpress
Proton therapy is not offered for the majority of patients with breast cancer. However, there are some circumstances where there may be a benefit.
NHS England Evidence review: Proton beam therapy for …
• Proton beam therapy (PBT) is an alternative to conventional photon radiotherapy. • Photons deliver a continuous energy beam which can cause damage to surrounding healthy tissue …
Proton therapy for breast cancer: Reducing toxicity - Wiley …
Proton therapy (PT) is a new and rapidly developing radiotherapy method. In comparison with con-ventional photon therapy, PT offers the benefits of decreased radiation toxicity and …
Planning and Treatment Recommendations for Breast Proton …
Despite the growing use of proton therapy for breast cancer, there are few recommendations for planning and treatment.
Proton therapy for the treatment of inflammatory breast cancer
Intensity modulated proton therapy (IMPT) is an attractive emerging modality for breast cancer due to unique physical prop- erties with rapid dose fall-off at the proton Bragg Peak [18,19].
Proton Therapy for Breast cancer
The good news is that with proton therapy, radiation can be stopped inside the tumor bed and breast tissue only, reducing or eliminating radiation dose to the heart and other critical structures.
Proton therapy—frequently asked questions. - MedStar Health
What types of cancers or tumors can proton therapy treat? Proton therapy can treat cancer anywhere in the body, including: • Brain tumors • Breast cancer • Gastrointestinal (GI) cancers • …
Proton therapy: Precise, proven treatment for breast cancer
“Proton therapy was the best treatment to take care of my breast cancer with less risk to my heart, my lungs, and my future.” —ProCure patient, breast cancer
Proton Therapy FAQ - Scripps Health
Specific tumor sites well-suited for proton therapy include breast, lung, prostate, spine, head, neck, brain, gastrointestinal tract and central nervous system, among others. Proton is also …
Proton Therapy for Breast Cancer: Progress & Pitfalls
Proton therapy is under investigation for early stage and locally advanced breast cancer. Due to unique physical properties, proton therapy reduces the dose to the heart, lungs, skin, muscle, …
Proton Therapy for Patients with Cancer - Northwestern …
Although tumors can be treated with surgery, chemotherapy and standard X-ray radiation, proton therapy can be particularly beneficial for patients with certain types of cancer and some non …
Proton Therapy in Breast Cancer: A Review of Volume 23: 1 …
Proton radiotherapy may be a compelling technical option for the treatment of breast cancer due to its unique physical property known as the “Bragg peak. This feature offers distinct …
COMMON QUESTIONS ABOUT PROTON THERAPY - Texas …
Proton therapy is a highly-targeted form of radiation therapy that is effective for cancerous tumors throughout the body. This cancer-fighting technology is non-invasive and may reduce …
Treating recurrent metastatic breast cancer to the skin with …
breast cancer, particularly when recurrent disease occurs near previously irradiated tissues. This case study demonstrates the dosimetric benefits of proton therapy in patients with metastatic …
Proton Reirradiation for Locoregionally Recurrent Breast Cancer
Proton therapy is recommended by the American Society for Radiation Oncology in cases where reirrradiation is needed; however, data are limited. We present the toxicity and outcomes after …
Proton therapy for early breast cancer patients in the DBCG …
In this study, we present the treatment strategy at the Danish Centre for Particle Therapy (DCPT) for patients referred to proton therapy based on the DBCG proton trial selection criteria.
The potential of proton beam radiation therapy in breast cancer
In primary breast cancer, it is estimated that about 300 of the annually 3425 irradiated patients can potentially be candidates for proton beam therapy to reduce late toxicity, mainly from the …