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| cons of ketamine therapy: Ketamine for Treatment-Resistant Depression Sanjay J. Mathew, Carlos A. Zarate, Jr., 2016-11-25 This book brings together an international group of clinicians and researchers from a broad swath of inter-related disciplines to offer the most up-to-date information about clinical and preclinical research into ketamine and second-generation “ketamine-like” fast-acting antidepressants. Currently available antidepressant medications act through monoaminergic systems, are ineffective for many individuals suffering from depression, and are associated with a delayed onset of peak efficacy of several months. The unexpected emergence of ketamine, an anesthetic N-methyl-D-aspartate (NMDA) receptor antagonist, as a rapid-acting antidepressant has reinvigorated CNS drug discovery research and catalyzed investigation in patient populations historically ignored in antidepressant drug development programs, particularly treatment-resistant patients and those with suicidality. Recent industry and academic research efforts have coalesced to explore NMDA receptor and glutamatergic molecular targets that lack ketamine’s psychotomimetic side effects and abuse liability but retain its rapid onset of efficacy. However, many fundamental questions remain regarding the neurobiological mechanisms underlying ketamine’s rapid antidepressant effects and the puzzling persistence of benefits observed in some patients following a single dose. This book examines how insights from these studies are forging new conceptual models of the neurobiology of stress-related affective, anxiety, and addictive disorders and the nature of treatment resistance. It also discusses how ketamine’s rapid antidepressant effects provide a scientific platform to facilitate innovation in clinical trial designs pertaining to patient selection, choice of control group, outcome measures, and dose-optimization. This book brings together data and insights from this rapidly expanding and extraordinarily promising field of study. Readers will be able to extract integrated themes and useful insights from the material contained in these diverse chapters and appreciate the paradigm-shifting contributions of ketamine to modern psychiatry and clinical neuroscience research. |
| cons of ketamine therapy: Acute Pain Management Raymond S. Sinatra, 2009-04-27 This textbook provides an overview of pain management useful to specialists as well as non-specialists, surgeons, and nursing staff. |
| cons of ketamine therapy: Ketamine for Treatment-Resistant Depression Gustavo H. Vazquez, Carlos A. Zarate, Elisa Brietzke, 2020-09-16 Ketamine for Treatment-Resistant Depression: Neurobiology and Applications provides a simple, evidence-based overview for neuropsychiatrists and translational researchers on this medication, its mechanisms of actions, eligibility of patients for treatment, and the preparation and implementation of ketamine clinics. - Provides efficacy research on ketamine as a treatment for depression - Identifies best practices for clinical use, both long-term and acute - Discusses the molecular mechanisms and neurobiology of action |
| cons of ketamine therapy: IV Ketamine Infusion Therapy for Depression Frank M Ligons, 2021-05-26 Ketamine infusions for depression relieve TWO-THIRDS of treatment-resistant cases. Is it addictive? What is a k hole? Cost and dosage? |
| cons of ketamine therapy: Treatment-resistant Mood Disorders Andre Carvalho, Roger S. McIntyre, 2015 Treatment-resistant major depression and bipolar disorder are highly prevalent and disabling conditions associated with substantial morbidity and mortality. Providing a concise view of the current definitions, assessment and evidence-based management of such disorders, this work reviews novel therapeutic targets, which may enhance the future therapeutic armamentarium of clinicians. |
| cons of ketamine therapy: Rapid Acting Antidepressants , 2020-06-29 The Advances in Pharmacology series presents a variety of chapters from the best authors in the field. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series |
| cons of ketamine therapy: Ketamine for Depression Dr. Stephen J. Hyde, 2015-09-04 Given the unacceptably high rates of suffering, disability and premature death experienced by people with treatment-resistant depression and the surprisingly low rates of problems arising from the use of ketamine to treat the disorder, this is a therapy that all patients and their doctors should be discussing. This book summarises the research that has been carried out into ketamine for the treatment of depression over the past 15 years and, most importantly, describes different ways of using ketamine that are both practical and cost–effective. Currently most ketamine therapy is given intravenously in specialised clinics at considerable expense, but the author has successfully treated patients with low-dose sublingual ketamine and his patients have been able to safely take this at home. Profits from the sales of this book will assist further research into the use of ketamine for the treatment of depression. |
| cons of ketamine therapy: Say Why to Drugs Suzi Gage, 2020-01-23 'Essential' Adam Rutherford, bestselling author of How to Argue With a Racist 'In an area where factual accuracy is often rejected in favour of moralising or panicking this book is a vitally useful and frequently fascinating' Robin Ince __________ Drugs. We've all done them. Whether it's a cup of coffee or a glass of wine, a cigarette or a sleeping pill. But how well do we understand the effects of the drugs we take - legal or illegal? Say Why to Drugs investigates the science behind recreational drugs- debunking common myths and misconceptions, as well as containing the most recent scientific research. Looking at a range of drugs, this book provides a clear understanding of how drugs work and what they're really doing to your mind and body. Along the way you will find out why ketamine is on the WHO's list of essential medicines, why some researchers hope MDMA could treat PTSD, and much more. Enlightening, entertaining, and thought-provoking, Say Why to Drugs is a compelling read that will surprise and educate proponents on both sides of the drugs debate. __________ A definitive and authoritative guide to drugs and why we get high from the creator of the top-rated podcast, Say Why to Drugs. |
| cons of ketamine therapy: The Ketamine Papers Phil Wolfson, Glenn Hartelius, 2016-11 The Ketamine Papers opens the door to a broad understanding of this medicine's growing use in psychiatry and its decades of history providing transformative personal experiences. Now gaining increasing recognition as a promising approach to the treatment of depression, posttraumatic stress disorder (PTSD), and other psychological conditions, ketamine therapies offer new hope for patients and clinicians alike. With multiple routes of administration and practices ranging from anesthesia to psychotherapy, ketamine medicine is a diverse and rapidly growing field. The Ketamine Papers clarifies the issues and is an inspiring introduction to this powerful tool for healing and transformation--from its early use in the 1960s to its emerging role in the treatment of depression, suicidality, and other conditions. This comprehensive volume is the ideal introduction for patients and clinicians alike, and for anyone interested in the therapeutic and transformative healing power of this revolutionary medicine. |
| cons of ketamine therapy: Drug-Induced Liver Injury , 2019-07-13 Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series |
| cons of ketamine therapy: Modern Anesthetics Jürgen Schüttler, Helmut Schwilden, 2008-01-08 Some important constraints of anesthesia must be taken into consideration when the pharmacological properties of modern anesthetics are discussed. The most imp- tant of these could be that the target effect be achieved preferably within seconds, at most within a few minutes. Similarly, offset of drug action should be achieved within minutes rather hours. The target effects, such as unconsciousness, are pot- tially life-threatening, as are the side effects of modern anesthetics, such as respi- tory and cardiovascular depression. Finally, the patient’s purposeful responses are not available to guide drug dosage, because, either the patient is unconscious, or more problematically, the patient is aware but unable to communicate pain because of neuromuscular blockade. These constraints were already recognised 35 years ago, when in 1972 Volume XXX entitled “Modern Inhalation Anesthetics” appeared in this Handbook Series. The present volume is meant as a follow up and extension of that volume. At the beginning of the 1970’s anesthesia was commonly delivered by inhalation, with only very few exceptions. The clinical understanding of that time considered anesthesia as a unique state achieved by any of the inhalation anesthetics, in- pendent of their specific molecular structure. “The very mechanism of anesthetic action at the biophase” was discussed within the theoretical framework of the “u- tary theory of narcosis”. |
| cons of ketamine therapy: Compounded Topical Pain Creams National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division, Board on Health Sciences Policy, Committee on the Assessment of the Available Scientific Data Regarding the Safety and Effectiveness of Ingredients Used in Compounded Topical Pain Creams, 2020-07-21 Pain is both a symptom and a disease. It manifests in multiple forms and its treatment is complex. Physical, social, economic, and emotional consequences of pain can impair an individual's overall health, well-being, productivity, and relationships in myriad ways. The impact of pain at a population level is vast and, while estimates differ, the Centers for Disease Control and Prevention reported that 50 million U.S. adults are living in pain. In terms of pain's global impact, estimates suggest the problem affects approximately 1 in 5 adults across the world, with nearly 1 in 10 adults newly diagnosed with chronic pain each year. In recent years, the issues surrounding the complexity of pain management have contributed to increased demand for alternative strategies for treating pain. One such strategy is to expand use of topical pain medicationsâ€medications applied to intact skin. This nonoral route of administration for pain medication has the potential benefit, in theory, of local activity and fewer systemic side effects. Compounding is an age-old pharmaceutical practice of combining, mixing, or adjusting ingredients to create a tailored medication to meet the needs of a patient. The aim of compounding, historically, has been to provide patients with access to therapeutic alternatives that are safe and effective, especially for people with clinical needs that cannot otherwise be met by commercially available FDA-approved drugs. Compounded Topical Pain Creams explores issues regarding the safety and effectiveness of the ingredients in these pain creams. This report analyzes the available scientific data relating to the ingredients used in compounded topical pain creams and offers recommendations regarding the treatment of patients. |
| cons of ketamine therapy: Ketamine Infusions Berkley Jones, 2020-03-25 This is the 2nd Edition of a Patients guide to Ketamine Infusions. We have added over 40 pages of new content of what you should know prior to getting your infusions. Ketamine is an old anesthetic drug developed in the 1960's. Over the past 20 years researchers began to figure out that Ketamine is much more versatile than simply being used for anesthesia. It can also be used to treat different kinds of Chronic Pain such as the pain from CRPS, Neuropathic Pain, and Small Fiber Neuropathy to name a few. Researchers have also discovered that Ketamine can significantly improve one's mood and are using it to treat Depression, Anxiety, OCD, PTSD, and certain types of Bipolar illness.Are you considering getting Ketamine to treat your Chronic Pain or Mental Health issues? Have you started looking into where to go and who can treat you? Are you wondering what to expect during Ketamine treatments?This book will guide you with everything from choosing your provider, to what to expect during your infusion experience, and how to get the best results from your infusions.This book was written with the input of physicians and patients from around the world and was accumulated with data amassed over the last 20 years.If you are considering infusions reading this book should be your first step before making the call to your local infusion clinic. |
| cons of ketamine therapy: Davis's Drug Guide for Rehabilitation Professionals Charles D. Ciccone, 2013-03-21 A one-of-a-kind guide specifically for rehabilitation specialists! A leader in pharmacology and rehabilitation, Charles Ciccone, PT, PhD offers a concise, easy-to-access resource that delivers the drug information rehabilitation specialists need to know. Organized alphabetically by generic name, over 800 drug monographs offer the most up-to-date information on drug indications, therapeutic effects, potential adverse reactions, and much more! A list of implications for physical therapy at the end of each monograph helps you provide the best possible care for your patients. It’s the perfect companion to Pharmacology in Rehabilitation, 4th Edition! |
| cons of ketamine therapy: Versed Rae Armantrout, 2010-08 A collection of poetry organized in two sections. The first section, Versed, play with vice and versa, the perversity of human consciousness. They flirt with error and delusion, skating on a thin ice that inevitably cracks. The second section, Dark Matter, alludes to more than the unseen substance thought to make up the majority of mass in the universe. The invisible and unknowable are confronted directly as the author's experience with cancer marks these poems with a new austerity, shot through with her signature wit and stark unsentimental thinking.--Résumé de l'éditeur. |
| cons of ketamine therapy: Hepatotoxicity Hyman J. Zimmerman, 1999 Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury. |
| cons of ketamine therapy: Ketamine Bita Moghaddam, 2021-02-16 The emergence of ketamine--previously known as a combat anesthetic and club drug--as a treatment for depression. Ketamine, approved in 2019 by the Food and Drug Administration for the treatment of depression, has been touted by scientists and media reports as something approaching a miracle cure. This volume in the MIT Press Essential Knowledge series chronicles the ascent of a drug that has been around for fifty years--in previous incarnations, a Vietnam-era combat anesthetic and a popular club drug--that has now been reinvented as a treatment for depression. Bita Moghaddam, a leading researcher in neuropharmacology, explains the scientific history and the biology of ketamine, its clinical use, and its recently discovered antidepressant effects, for the nonspecialist reader. |
| cons of ketamine therapy: Plumb's Veterinary Drug Handbook Donald C. Plumb, 2018-02-21 Plumb’s Veterinary Drug Handbook, Ninth Edition updates the most complete, detailed, and trusted source of drug information relevant to veterinary medicine. Provides a fully updated edition of the classic veterinary drug handbook, with carefully curated dosages per indication for clear guidance on selecting a dose Features 16 new drugs Offers an authoritative, complete reference for detailed information about animal medication Designed to be used every day in the fast-paced veterinary setting Includes dosages for a wide range of species, including dogs, cats, exotic animals, and farm animals |
| cons of ketamine therapy: Pain Management and the Opioid Epidemic National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division, Board on Health Sciences Policy, Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse, 2017-09-28 Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring. |
| cons of ketamine therapy: Antidepressants Matthew Macaluso, Sheldon H. Preskorn, 2019-05-31 This volume reviews the known neurobiology of depression and combines classic data on antidepressant treatments with modern theory on the physiology of depression. It also discusses novel mechanism of action drugs. |
| cons of ketamine therapy: Internal Family Systems Therapy Richard C. Schwartz, 2013-09-18 This book has been replaced by Internal Family Systems Therapy, Second Edition, ISBN 978-1-4625-4146-1. |
| cons of ketamine therapy: The Body Keeps the Score Bessel A. Van der Kolk, 2015-09-08 Originally published by Viking Penguin, 2014. |
| cons of ketamine therapy: Cafer's Psychopharmacology Jason Cafer, 2020-11 Cafer's Psychopharmacology is an essential resource for any prescriber of psychiatric medication. Filled with pictures, this book makes complex concepts easy to understand and provides tools for remembering more than you thought possible. To help you match trade names with generic names of 270 medications, this book features mascots akin to the Xyzal Wise Owl and Myrbetriq Bladder characters. Each medication's mascot is incorporated into a visual-mnemonic framework designed for recollection of pharmacokinetic interactions. For instance, CYP2C19 substrates are represented as flowers with CYP2C19 inhibitors as watering cans to make the flowers grow. CYP1A2 substrates are trees to be chopped down by axes (CYP1A2 inducers). Lithium is a battery and anything that interferes with its renal excretion is depicted as a battery charger. |
| cons of ketamine therapy: Handbook of Depression Ernest Edward Beckham, William R. Leber, 1985 |
| cons of ketamine therapy: Global Status Report on Alcohol and Health 2018 World Health Organization, 2018 The report provides an overview of alcohol consumption and harms in relation to the UN Sustainable Development Goals (Chapter 1) presents global strategies action plans and monitoring frameworks (Chapter 2) gives detailed information on: the consumption of alcohol in populations (Chapter 3); the health consequences of alcohol consumption (Chapter 4); and policy responses at national level (Chapter 5). In its final chapter 6 the imperative for reducing harmful use of alcohol in a public health perspective is presented. In addition the report contains country profiles for WHO Member States and appendices with statistical annexes a description of the data sources and methods used to produce the estimates and references. |
| cons of ketamine therapy: I Had a Black Dog Matthew Johnstone, 2012-03-01 'I Had a Black Dog says with wit, insight, economy and complete understanding what other books take 300 pages to say. Brilliant and indispensable.' - Stephen Fry 'Finally, a book about depression that isn't a prescriptive self-help manual. Johnston's deftly expresses how lonely and isolating depression can be for sufferers. Poignant and humorous in equal measure.' Sunday Times There are many different breeds of Black Dog affecting millions of people from all walks of life. The Black Dog is an equal opportunity mongrel. It was Winston Churchill who popularized the phrase Black Dog to describe the bouts of depression he experienced for much of his life. Matthew Johnstone, a sufferer himself, has written and illustrated this moving and uplifting insight into what it is like to have a Black Dog as a companion and how he learned to tame it and bring it to heel. |
| cons of ketamine therapy: Identifying, Treating, and Preventing Childhood Trauma in Rural Communities Baker, Marion, Ford, Jacqueline, Canfield, Brittany, Grabb, Traci, 2016-06-09 While there have been great strides made in the treatment options available to trauma victims, there is a noticeable gap in the availability of medical, social, and psychological options in rural communities. As these hurdles gain more recognition, especially in regards to traumatized children, research efforts have been intensified in an effort to increase the overall awareness of and find solutions to the improper treatment being provided. Identifying, Treating, and Preventing Childhood Trauma in Rural Communities depicts the issues and challenges rural areas face when treating victims of trauma, especially children and adolescents. Featuring information on language and cultural barriers, as well as the lack of resources available within these rustic environments, this publication serves as a critical reference for researchers, clinicians, educators, social workers, and medical providers. |
| cons of ketamine therapy: Ketamine David T. Yew, 2015-03-16 Increasing use of ketamine as a recreational drug in Asia, Europe, and America is a great burden on society at large, leading to aspirational strain, unemployment, and crime. These societal effects have led to growing interest among researchers and clinicians in ketamine's effects on various systems of the body. Ketamine: Use and Abuse reviews the |
| cons of ketamine therapy: Consciousness Medicine Françoise Bourzat, Kristina Hunter, 2019-06-25 A comprehensive guide to the safe and ethical application of expanded states of consciousness for therapists, healing practitioners, and sincere explorers Psychedelic medicines also known as entheogens are entering the mainstream. And it’s no wonder: despite having access to the latest wellness trends and advances in technology, we’re no healthier, happier, or more meaningfully connected. Psilocybin mushrooms, ayahuasca, and LSD—as well as other time-tested techniques with the power to shift consciousness such as drumming, meditation, and vision quests—are now being recognized as potent catalysts for change and healing. But how do we ensure that we’re approaching them effectively? Françoise Bourzat—a counselor and experienced guide with sanctioned training in the Mazatec and other indigenous traditions—and healer Kristina Hunter introduce a holistic model focusing on the threefold process of preparation, journey, and integration. Drawing from more than thirty years of experience, Bourzat’s skillful and heartfelt approach presents the therapeutic application of expanded states, without divorcing them from their traditional contexts. Consciousness Medicine delivers a coherent map for navigating nonordinary states of consciousness, offering an invaluable contribution to the field of healing and transformation. |
| cons of ketamine therapy: Relieving Pain in America Institute of Medicine, Board on Health Sciences Policy, Committee on Advancing Pain Research, Care, and Education, 2011-10-26 Chronic pain costs the nation up to $635 billion each year in medical treatment and lost productivity. The 2010 Patient Protection and Affordable Care Act required the Department of Health and Human Services (HHS) to enlist the Institute of Medicine (IOM) in examining pain as a public health problem. In this report, the IOM offers a blueprint for action in transforming prevention, care, education, and research, with the goal of providing relief for people with pain in America. To reach the vast multitude of people with various types of pain, the nation must adopt a population-level prevention and management strategy. The IOM recommends that HHS develop a comprehensive plan with specific goals, actions, and timeframes. Better data are needed to help shape efforts, especially on the groups of people currently underdiagnosed and undertreated, and the IOM encourages federal and state agencies and private organizations to accelerate the collection of data on pain incidence, prevalence, and treatments. Because pain varies from patient to patient, healthcare providers should increasingly aim at tailoring pain care to each person's experience, and self-management of pain should be promoted. In addition, because there are major gaps in knowledge about pain across health care and society alike, the IOM recommends that federal agencies and other stakeholders redesign education programs to bridge these gaps. Pain is a major driver for visits to physicians, a major reason for taking medications, a major cause of disability, and a key factor in quality of life and productivity. Given the burden of pain in human lives, dollars, and social consequences, relieving pain should be a national priority. |
| cons of ketamine therapy: Ketamine Karl Jansen, 2001-01-01 |
| cons of ketamine therapy: CRPS Peter R. Wilson, Michael d'A. Stanton-Hicks, R. Norman Harden, 2005 Complex regional pain syndrome is a medically and economically significant condition that is disproportionate to the inciting event. Until now, it has been difficult to make the diagnosis, but this volume presents validated diagnostic criteria for the condition. Treatment for the condition has been hampered by the lack of good clinical evidence. This volume summarizes all reported treatments and evaluates the scientific evidence for each. A treatment algorithm is presented. This is a text that will be invaluable for the clinician, and for all those who address the issues of CRPS in the medical, rehabilitation, public health, or medicolegal fields. |
| cons of ketamine therapy: Interpretative Phenomenological Analysis Jonathan A Smith, Paul Flowers, Michael Larkin, 2012-08-14 ′It is not often I can use accessible and phenomenology in the same sentence, but reading the new book, Interpretative Phenomenological Analysis...certainly provides me the occasion to do so. I can say this because these authors provide an engaging and clear introduction to a relatively new analytical approach′ - The Weekly Qualitative Report Interpretative phenomenological analysis (IPA) is an increasingly popular approach to qualitative inquiry. This handy text covers its theoretical foundations and provides a detailed guide to conducting IPA research. Extended worked examples from the authors′ own studies in health, sexuality, psychological distress and identity illustrate the breadth and depth of IPA research. Each of the chapters also offers a guide to other good exemplars of IPA research in the designated area. The final section of the book considers how IPA connects with other contemporary qualitative approaches like discourse and narrative analysis and how it addresses issues to do with validity. The book is written in an accessible style and will be extremely useful to students and researchers in psychology and related disciplines in the health and social sciences. |
| cons of ketamine therapy: Mechanisms of Vascular Disease Robert Fitridge, M. M. Thompson, 2011 New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes. |
| cons of ketamine therapy: Suicide, COVID-19, and Ketamine Johnathan Edwards, 2021-08-15 Why a book about suicide, COVID-19, and Ketamine? These delicate topics are more inter-related than you might think. The World Health Organization (WHO) estimates that each year 800,000 people die from suicide. But have you wondered about the long-term unintended consequences of COVID-19? The deluge of mental-health problems like depression, suicide, and drug overdoses resulting from the pandemic. Depression, suicide and drug overdoses have been a problem since long before the pandemic. But COVID-19 has made the situation worse: it is more of a crisis than a pandemic. Lockdowns have fueled a litany of tragedies: suicides, drug overdoses, heightened crime, starvation, financial ruin, and much more. Adolescent and adult mental illness have skyrocketed during the crisis, and the tsunami of post-traumatic stress, depression, and suicides will follow. The mental-health consequences will persist long after the COVID-19 pandemic ends. Because of the lockdowns, we expect millions of people will die of hunger and postponed medical treatments, a potential outcome that, unfortunately, has developed less notice. The result is a perfect storm of suicides and drug overdose deaths. Mental-health practitioners are employing everything, including telemedicine, to help people battle this threat. Suicide is subtle, and the decision to take your own life is often impulsive. The treatment of suicide and depression is complex, with current medications taking weeks or months to work. When a loved one commits suicide, they leave many unanswered questions. Constant thoughts of what and why, permeate the minds of those left behind. We do not have many effective treatments for suicide. But there is one drug that can often stop suicide in its tracks: ketamine. Few are aware that this decades-old anesthetic and party drug might save your loved one's or even your life. Our goal is to convince you ketamine is a legitimate path to treat mental disorders. Simply said, ketamine works. If your loved one was suicidal, would you suggest trying ketamine? Or use it yourself? |
| cons of ketamine therapy: The Essential Psychedelic Guide D. M. Turner, 1994 |
| cons of ketamine therapy: Hello I Want to Die Please Fix Me Anna Mehler Paperny, 2020-03-31 An engrossing memoir-meets-investigative report that takes a fresh, frank look at how we treat depression. Depression is a havoc-wreaking illness that masquerades as personal failing and hijacks your life. After a major suicide attempt in her early twenties, Anna Mehler Paperny resolved to put her reporter’s skills to use to get to know her enemy, setting off on a journey to understand her condition, the dizzying array of medical treatments on offer, and a medical profession in search of answers. Charting the way depression wrecks so many lives, she maps competing schools of therapy, pharmacology, cutting-edge medicine, the pill-popping pitfalls of long-term treatment, the glaring unknowns and the institutional shortcomings that both patients and practitioners are up against. She interviews leading medical experts across the US and Canada, from psychiatrists to neurologists, brain-mapping pioneers to family practitioners, and others dabbling in strange hypotheses—and shares compassionate conversations with fellow sufferers. Hello I Want to Die Please Fix Me tracks Anna’s quest for knowledge and her desire to get well. Impeccably reported, it is a profoundly compelling story about the human spirit and the myriad ways we treat (and fail to treat) the disease that accounts for more years swallowed up by disability than any other in the world. If you or someone you know is struggling with suicidal thoughts, help is available. Contact the National Suicide Prevention Lifeline at 800-273-8255. |
| cons of ketamine therapy: The ECT Handbook I. Nicol Ferrier, Jonathan Waite, 2019-07-04 The fourth edition of this popular Handbook provides the latest guidance on prescribing and administering electroconvulsive therapy (ECT). Leading researchers and practitioners review new research on ECT and related treatments, including their efficacy in children and adolescents, and in those with bipolar disorder and neurological conditions. With a focus on safe provision and minimisation of side effects, it provides the reader with practical, evidence-based advice. The book has been substantially revised: references have been updated throughout; related treatment modalities such as rTMS, tCDS and ketamine are covered in greater depth; and current administrative and legal framework guidelines are clearly outlined. An essential reference manual for consultant and trainee clinical psychiatrists, as well as ECT practitioners. This guide will benefit clinical teams looking after complex cases of depression, as well as those involved in the care of other people for whom ECT may be recommended. |
| cons of ketamine therapy: Inflammation and Immunity in Depression Bernhard Baune, 2018-05-23 Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recent lines of research into this rapidly advancing field, including alterations of T-cells, the neurobiological implications of neuroinflammation and immune alterations for brain development and function, and the genetic components of neuroinflammation in depression, including the relationships between stress and inflammation that are revealing gene-environment interactions in the disorder. Combining contributions from researchers worldwide, this book provides the most comprehensive discussion available today on the involvement of the innate immune and adaptive immune systems in depressive disorder. Chapters span neuroscience, psychology, clinical applications and future directions, making this book an invaluable resource for advanced students, researchers and practitioners who need to understand the complex and varied role of inflammation and immune responses in depression. - Synthesizes current knowledge of inflammation and immunity in depression, ranging from basic neuroscience research, to clinical applications in psychiatry - Expands on the long-established theory of cytokine-induced depression to discuss broader involvement of the immune system - Explores translational potential of targeting immune dysfunction for clinical interventions |
| cons of ketamine therapy: Managing Treatment-Resistant Depression Joao Luciano de Quevedo, Patricio Riva-Posse, William V. Bobo, 2022-04-04 Managing Treatment-Resistant Depression: Road to Novel Therapeutics defines TRD for readers, discussing the clinical and epidemiological predictors, economic burden and neurobiological factors. In addition, staging methods for treatment resistance are fully covered in this book, including serotonin specific reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, other classes of antidepressants, including tricyclic antidepressants and monoamine oxidase inhibitors, augmentation strategies, and newer antidepressant treatments like ketamine and esketamine. In addition, evidence supporting the use of psychotherapies and neuromodulation strategies are also reviewed. Written by top experts in the field, this book is the first of its kind to review all methods of treatment for TRD. Defines Treatment-Resistant Depression and Staging Treatment Intensity Includes Treatment-Resistant Depression options for children, adolescents, geriatrics, during pregnancy, and during post-partum and menopause transitions Discusses the use of Ketamine and Esketamine for treatment-resistant depression |
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Mar 24, 2016 · Living in Denver, the high altitude brings low humidity, few bugs, and strong sun in the winter that melts snow fast and makes a …
Cumberland MD Pros/Cons? (Baltimore, Columbia: wood fl…
Aug 29, 2023 · Western NC move: factors- pros and cons, Western North Carolina, 11 replies FL vs. GA - Pros and Cons , Florida, 3 replies Augusta -pros & cons, nice outlying areas? , Augusta …
Pros and Cons working in Civil Service for NYC vs New York S…
Oct 28, 2016 · I am already city service but don't mind starting over in State, just recieved a Canvass letter for exam for state i took back in 2010 list was extended to 2018...
pros and cons of living in Coppell (Dallas, Irving: to rent…
Jun 22, 2012 · pros and cons of using an RE agent with new construction., Dallas, 12 replies pros/cons to living in the la villita development in las colinas?, Dallas, 9 replies Pros and Cons of …
Pros and Cons of living in Irmo SC (Columbia, Lexington: low i…
Nov 30, 2016 · Pros and Cons of living in NYC?What is the point of living here anymore?, New York City, 180 replies Pros and Cons of living in Oxnard and Santa Maria, California, 6 replies …
