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| case study multiple sclerosis: Case Studies in Multiple Sclerosis Paul S. Giacomini, 2016-10-06 This handbook is a collection of clinical narratives that underscore the heterogeneous and unpredictable presentation of multiple sclerosis (MS) and give real-world clinical context to recent drug developments. This accessible and concise publication is intended to be used by a wide range of medical professionals, from specialist neurologists to medical trainees with an interest in neurology. An ideal clinical resource, Case Studies in Multiple Sclerosis provides an evidence-based discussion of each case, with an aim to enhance effective diagnosis and treatment of patients with MS and MS-related conditions. |
| case study multiple sclerosis: Multiple Sclerosis Institute of Medicine, Board on Neuroscience and Behavioral Health, Committee on Multiple Sclerosis: Current Status and Strategies for the Future, 2001-08-10 Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families. |
| case study multiple sclerosis: Multiple Sclerosis T. Jock Murray, MD, 2004-12-01 Multiple Sclerosis: The History of a Disease won a 2005 ForeWord Book of the Year Silver Medal! The basic facts about multiple sclerosis are well known: it is the most common neurologic disease of young adults, usually beginning with episodic attacks of neurologic symptoms, then entering a progressive phase some years later. Its onset has an average age of 30, and occurs in about 1 in 500 individuals of European ancestry living primarily in temperate climates. There appears to be a complex interaction between a genetic predisposition and an environmental trigger that initiates the disease. But these facts do not convey the impact of the disease on the people whose lives it affects. In this elegantly written and comprehensive history, we meet individuals who suffered with MS in the centuries before the disease had a name, including blessed Lidwina of Holland, who took joy from her misery, believing that she was sent to accept suffering for the sins of others; Augustus d'Est, grandson of George III and cousin of Queen Victoria, whose case shows how someone with access to the best of medical care of the age was understood and managed; and Heinrich Heine, the great German poet, who also had access to all medical services that were available, but who progressed into his mattress grave in two decades, aware of the loss of physical ability while still able to compose great poetry to the end. From these early cases the author demonstrates how progress in diagnosing and managing multiple sclerosis has paralleled the development of medical science, from the early developments in modern studies of anatomy and pathology, to the framing of the disease in the nineteenth century, and eventually to modern diagnosis and treatment. From beginning to end, Dr. Murray takes us on a fascinating journey of discovery, in the process showing how the evolution of our understanding of multiple sclerosis has been part of the greater history of medical knowledge. |
| case study multiple sclerosis: Impacts of Information Technology on Patient Care and Empowerment McHaney, Roger W., Reychev, Iris, Azuri, Joseph, McHaney, Mark E., Moshonov, Rami, 2019-09-20 Modern technology has impacted healthcare and interactions between patients and healthcare providers through a variety of means including the internet, social media, mobile devices, and the internet of things. These new technologies have empowered, frustrated, educated, and confused patients by making educational materials more widely available and allowing patients to monitor their own vital signs and self-diagnose. Further analysis of these and future technologies is needed in order to provide new approaches to empowerment, reduce mistakes, and improve overall healthcare. Impacts of Information Technology on Patient Care and Empowerment is a critical scholarly resource that delves into patient access to information and the effect that access has on their relationship with healthcare providers and their health outcomes. Featuring a range of topics such as gamification, mobile computing, and risk analysis, this book is ideal for healthcare practitioners, doctors, nurses, surgeons, hospital staff, medical administrators, patient advocates, researchers, academicians, policymakers, and healthcare students. |
| case study multiple sclerosis: Clinical Case Studies in Physiotherapy Lauren Jean Guthrie, 2008-10-09 Starting a placement or rotation in an unfamiliar clinical area is exciting but can be daunting. CLINICAL CASE STUDIES IN PHYSIOTHERAPY provides invaluable advice and practical guidance on cases and problems encountered on a daily basis allowing you to work with ease and confidence. By adopting a problem solving approach to the cases through the use of questions and answers, the authors will help you to think constructively about each case within all the key specialities of physiotherapy.Starting a placement or rotation in an unfamiliar clinical area is exciting but can be daunting. CLINICAL CASE STUDIES IN PHYSIOTHERAPY provides invaluable advice and practical guidance on cases and problems encountered on a daily basis allowing you to work with ease and confidence. By adopting a problem solving approach to the cases through the use of questions and answers, the authors will help you to think constructively about each case within all the key specialities of physiotherapy. - Hints and tips to get you ready for clinical placement - How to secure your first physiotherapy post - Case studies in the following clinical areas: respiratory, orthopaedics, neurology, musculoskeletal out-patients, care of the elderly, mental health and womens health - Cases covering paediatrics also included |
| case study multiple sclerosis: Dietetic and Nutrition Judy Lawrence, Pauline Douglas, Joan Gandy, 2016-05-02 The ideal companion resource to ‘Manual of Dietetic Practice’, this book takes a problem-based learning approach to dietetics and nutrition with cases written and peer reviewed by registered dietitians, drawing on their own experiences and specialist knowledge Each case study follows the Process for Nutrition and Dietetic Practice published by the British Dietetic Association in 2012 Includes case studies in public health, an increasingly important area of practice |
| case study multiple sclerosis: McAlpine's Multiple Sclerosis Alastair Compston, 1998 This is the latest edition of the classic book on the subject of multiple sclerosis. An international group of authors has been involved in updating this edition which features more information on imaging and investigations, and a new chapter on neurobiology and glial development. |
| case study multiple sclerosis: Neuromuscular Case Studies Tulio E. Bertorini, 2008-05-06 In this unique book, Dr. Bertorini guides you through more than 100 cases that demonstrate the diagnosis and management of a wide range of common and rare neuromuscular disorders. No other reference boasts such a large array of clinical studies devoted to all areas of this broad topic! Each case study reviews the etiologies, pathogenesis, differential diagnosis, and management of a particular disorder, helping you not only recognize its presentation, but also determine a diagnosis and the best treatment plans for your patients. You'll also find expert guidance on the basic mechanisms of neuromuscular disorders, clinical examination, and diagnostic tests—including EMG, muscle biopsy, genetic testing, and more. - More than 100 detailed case studies explore both common and rare neuromuscular disorders and the treatment protocols for each, equipping you with the knowledge you need to confidently manage any challenge. Each case includes a summary of important points or highlights of the study. - Case studies are arranged either by complaint or by diagnosis so that you can successfully manage your patients with or without an initial diagnosis. - Comprehensive coverage of EMGs and nerve conduction studies and other diagnostic tests, including muscle and nerve biopsies and genetic testing, helps you accurately diagnose nerve, muscle, and neuromuscular transmission disorders. - Detailed discussions of treatment plans and commonly used drugs enhance your management of autoimmune disorders, painful neuropathy, dysautonomia, and other neuromuscular disorders. - A reader-friendly format takes you step by step through the diagnosis and treatment of neuromuscular disorders, from the basic anatomy and physiology of the nerve and muscle through to clinical evaluation, diagnostic testing, and therapy. - More than 350 high-quality illustrations, including full-color patient photographs, biopsies, and EMG tracings, make complex concepts easier to understand and apply. |
| case study multiple sclerosis: Neuroimmune Diseases Hiroshi Mitoma, Mario Manto, 2019-08-13 A translational overview of neuroimmune diseases for neuroscientists and clinicians that clarifies the pathological mechanisms underlying neuroimmune diseases and builds a comprehensive bridge between the latest research findings and their clinical implications in daily practice. The material is presented in two steps. The first section comprises a review of the pathogenic actions of immune cells in brain diseases. Here the authors discuss the mechanisms through which immune cells disrupt the functions of nerve cells. The second section explores the ways in which the brain becomes dysfunctional due to impaired nerve cell function. Based on pathogenesis, diagnostic and therapeutic strategies are discussed for each clinical category. The book will be invaluable for use in clinical practice of neuroimmune diseases |
| case study multiple sclerosis: Economic Dimensions of Personalized and Precision Medicine Ernst R. Berndt, Dana P. Goldman, John Rowe, 2019-04-22 Personalized and precision medicine (PPM)—the targeting of therapies according to an individual’s genetic, environmental, or lifestyle characteristics—is becoming an increasingly important approach in health care treatment and prevention. The advancement of PPM is a challenge in traditional clinical, reimbursement, and regulatory landscapes because it is costly to develop and introduces a wide range of scientific, clinical, ethical, and socioeconomic issues. PPM raises a multitude of economic issues, including how information on accurate diagnosis and treatment success will be disseminated and who will bear the cost; changes to physician training to incorporate genetics, probability and statistics, and economic considerations; questions about whether the benefits of PPM will be confined to developed countries or will diffuse to emerging economies with less developed health care systems; the effects of patient heterogeneity on cost-effectiveness analysis; and opportunities for PPM’s growth beyond treatment of acute illness, such as prevention and reversal of chronic conditions. This volume explores the intersection of the scientific, clinical, and economic factors affecting the development of PPM, including its effects on the drug pipeline, on reimbursement of PPM diagnostics and treatments, and on funding of the requisite underlying research; and it examines recent empirical applications of PPM. |
| case study multiple sclerosis: Research Anthology on Diagnosing and Treating Neurocognitive Disorders Management Association, Information Resources, 2020-08-30 Cognitive impairment, through Alzheimer’s disease or other related forms of dementia, is a serious concern for afflicted individuals and their caregivers. Understanding patients’ mental states and combatting social stigmas are important considerations in caring for cognitively impaired individuals. Technology is playing an increasing role in the lives of the elderly. One of the most prevalent developments for the aging population is the use of technological innovations for intervention and treatment of individuals with mental impairments. Research Anthology on Diagnosing and Treating Neurocognitive Disorders examines the treatment, diagnosis, prevention, and therapeutic and technological interventions of neurodegenerative disorders. It also describes programs and strategies that professional and family caregivers can implement to engage and improve the quality of life of persons suffering from cognitive impairment. Highlighting a range of topics such as dementia, subjective wellbeing, and cognitive decline, this publication is an ideal reference source for speech pathologists, social workers, occupational therapists, psychologists, psychiatrists, neurologists, pediatricians, researchers, clinicians, and academicians seeking coverage on neurocognitive disorder identification and strategies for clinician support and therapies. |
| case study multiple sclerosis: White Matter Diseases Massimo Filippi, Maria A. Rocca, 2020-02-13 This book provides cutting-edge information on the epidemiology, etiopathogenesis, clinical manifestations, diagnostic procedures and treatment approaches for the main white matter (WM) disorders of the central nervous system (CNS). WM lesions are associated with many neurological conditions, and with aging. The diagnostic work-up of neurological diseases characterized by the presence of these lesions has changed dramatically over the past few years. This is mainly due on the one hand to the discovery of specific pathogenetic factors in some of these conditions, and on the order to the optimized use of diagnostic tools. All of this has resulted in new diagnostic algorithms, and in the identification of new neurological conditions. The book offers neurologists essential guidance in the diagnosis and treatment of the most frequent WM conditions, promoting their correct and cost-saving diagnosis and management. By integrating neurological, laboratory and imaging concepts with the demands of accurate diagnosis, this reference guide provides a state-of-the-art overview of the current state of knowledge on these conditions, as well as practical guidelines for their diagnosis and treatment. |
| case study multiple sclerosis: Multiple Sclerosis Ian S. Zagon, Patricia J. McLaughlin, 2017 |
| case study multiple sclerosis: Case Studies in Systemic Sclerosis RICHARD SILVER, Christopher P. Denton, 2011-08-14 Case Studies in Systemic Sclerosis deals specifically with Systemic Sclerosis in a case study format. Each case presentation includes illustrative figures, a discussion of the pathophysiology relevant to the case, a discussion of management that is both evidence-based and expert opinion-based and several key references for further reading. With its easy-to-use format, this book presents multiple different manifestations of Systemic Sclerosis to a wide range of readers. Because this disease has a broad range of systemic features, Case Studies in Systemic Sclerosis is a valuable reference tool not only to the community of rheumatologists (trainees, academic and private practice rheumatologists) and dermatologists, but also potentially to internists, gastroenterologists, pulmonologists, cardiologists and nephrologists. |
| case study multiple sclerosis: Diseases of the Brain, Head and Neck, Spine 2020–2023 Juerg Hodler, Rahel A. Kubik-Huch, Gustav K. von Schulthess, 2020-02-14 This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care. |
| case study multiple sclerosis: Neurotropic Viral Infections Carol Shoshkes Reiss, 2016-09-08 This second edition is a comprehensive study of the viruses that affect the brain and the central nervous system. Along with a focus on the viruses themselves, it addresses the diseases they cause, current treatments and preventive measures. Also discussed are the unique aspects of how viruses cause disease and why certain hosts are more susceptible (e.g., polymorphisms, age, co-morbidities). Because there are 29 cutting edge chapters, written by experts in the fields, Neurotropic Viral Infections has been divided into two separate volumes. Volume 1, Neurotropic RNA Viruses, includes 14 chapters on RNA viruses that cause human disease of the central nervous system ranging from Bornavirus to polio to West Nile. Volume 2, Neurotropic Retroviruses, DNA Viruses, Immunity and Transmission, includes 15 chapters divided into two parts. Part 1 includes 7 chapters on retroviruses and DNA viruses that cause human disease of the central nervous system ranging from HIV to varicella zoster virus. Part 2 includes chapters on transmission of these viruses by transplantation, bites by bats and insects, clinical management of the infections, and beneficial uses of attenuated viruses. Neurotropic Viral Infections is a unique resource, bridging basic, clinical, and translational approaches. |
| case study multiple sclerosis: Fractured Minds Jenni A. Ogden, 2005-02-17 Fractured Minds introduces the reader to clinical neuropsychology through vivid case descriptions of adults who have suffered brain damage. At one level, this is a book about the courage, humor, and determination to triumph over illness and disability that many ordinary people demonstrate when coping with the extraordinary stress of a brain disorder. On another level, it is a well-referenced and up-to-date textbook that provides a holistic view of the practice of clinical neuropsychology. Included are reader-friendly descriptions and explanations of a wide range of neurological disorders and neuroscientific concepts. Two introductory chapters are followed by 17 chapters that each focus on a specific disorder and include research, clinical assessment, rehabilitation, and a detailed case study. Disorders range across the full spectrum from common ones such as traumatic brain injury and dementia, to rare disorders such as autotopagnosia. Each of the 16 chapters retained from the first edition has been revised to reflect current research and clinical advances. Three new chapters on multiple sclerosis, Parkinson's disease, and Huntington's disease incorporate discussion of important current topics such as genetically-transmitted diseases, genetic counseling, gene transplantation, functional neurosurgery, and the complex ethical issues that go hand-in-hand with these new techniques. This informative and engaging book will be of interest to students of clinical psychology, neuropsychology, and neurology, health professionals who work with neurological patients, neurological patients and their families, and lay readers who are simply fascinated by the mind and brain. |
| case study multiple sclerosis: Clinical Case Studies for the Family Nurse Practitioner Leslie Neal-Boylan, 2011-11-28 Clinical Case Studies for the Family Nurse Practitioner is a key resource for advanced practice nurses and graduate students seeking to test their skills in assessing, diagnosing, and managing cases in family and primary care. Composed of more than 70 cases ranging from common to unique, the book compiles years of experience from experts in the field. It is organized chronologically, presenting cases from neonatal to geriatric care in a standard approach built on the SOAP format. This includes differential diagnosis and a series of critical thinking questions ideal for self-assessment or classroom use. |
| case study multiple sclerosis: Multiple Sclerosis Therapeutics Richard Rudick, 1999-09-01 This textbook examines the most important aspects of multiple sclerosis that impact on clinical trial design, on the development of new disease therapies and on patient care. The international team of contributors discuss the clinical course of multiple sclerosis, its clinical heterogeneity, the presence of subclinical disease activity which occurs during the early stages of the disease. Multiple sclerosis presents clinical challenges: from unexpected and irregular relapses to profressive deterioration. |
| case study multiple sclerosis: McAlpine's Multiple Sclerosis Douglas McAlpine, Walter Bryan Matthews, 1991 This revised edition examines various aspects of the disease multiple sclerosis. It examines the advances in means of investigation, the increasing sophistication in the collection of epidemiological data and in the organization and assessment of therapeutic trials. |
| case study multiple sclerosis: Case-Based Neuro-Ophthalmology Jonathan Micieli, 2019-06-18 Case-Based Neuro-Ophthalmology is designed for ophthalmology and neurology residents learning neuro-ophthalmology. Multiple choice questions are a common way of assessing knowledge on standardized examinations, but are also a useful way to learn. This book aims to familiarize the reader with common neuro-ophthalmology case presentations and poses questions that must be considered before arriving at a coherent impression and plan. Common test questions are also included to help with preparation for standardized examinations.Key Features:- Neuroimaging review tailored to ophthalmology residents for high-yield topics and images relevant to neuro-ophthalmology- Optical coherence tomography chapter dedicated to high-yield topics for neurology and ophthalmology residents- 23 of the most common neuro-ophthalmology cases ranging from optic neuritis, ischemic optic neuropathy and 6th nerve palsy with a complete set of multiple choice questions, answers and explanations. - Clinical pearls are highlighted in Clinical Pearl boxes for the most high yield information |
| case study multiple sclerosis: Neuroimmunological Diseases Susumu Kusunoki, 2016-06-24 This book offers a detailed review of the remarkable advances that have been made in research on the pathogenesis of a number of neuroimmunological diseases, as well as outlining novel treatments including the use of monoclonal antibodies. Written by renowned experts who have made major contributions in the field, such as identifying neuromyelitis optica as an immunopathological clinical condition, identifying the role of ganglioside and ganglioside-complex antibodies in Guillain-Barré syndrome, and developing a novel treatment for POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes) syndrome, the book summarizes recent advances in basic and clinical research. Neuroimmunological Diseases is a useful resource for not only researchers but also neurologists who are engaged in the management of neuroimmunological diseases. |
| case study multiple sclerosis: CURRENT Diagnosis & Treatment Neurology, Second Edition John Brust, 2011-10-19 A handy, practical, and management-oriented neurology sourcebook – delivering everything you need in one easy-to-carry volume CURRENT Diagnosis & Treatment Neurology, 2e provides busy clinicians with practical, up-to-date strategies for assessing and managing the most frequently seen neurologic conditions in adults and children. Features Consistent presentation includes Essentials of Diagnosis, Symptoms and Signs, Diagnostic Studies, Differential Diagonsis, Treatment, and Prognosis Coverage of disorders in both adults and children Practical information on common conditions such as headaches, movement disorders, and central nervous system infections Expert help with ischemicand hemorrhagic stroke, epilepsy, sleeping disorders, dizziness, hearing loss, dementia and memory loss, psychiatric problems, and more Thorough coverage of diagnostic tests More than 100 informative photos and illustrations Updated with the latest findings and developments This second edition will be valuable to anyone who sees patients with neurologic complaints, whether in primary care or the neurology clinic. |
| case study multiple sclerosis: Lectures on the Diseases of the Nervous System Jean Martin Charcot, 1879 |
| case study multiple sclerosis: Case Studies in Pain Management Alan David Kaye, Rinoo V. Shah, 2014-10-16 Edited by internationally recognized pain experts, this book offers 73 clinically relevant cases, accompanied by discussion in a question-and-answer format. |
| case study multiple sclerosis: The Biology of Multiple Sclerosis Gregory Atkins, Sandra Amor, Jean Fletcher, Kingston Mills, 2012-11-08 Multiple sclerosis is the most common debilitating neurological disease in people under the age of forty in the developed world. Many publications cover medical and clinical approaches to the disease; however, The Biology of Multiple Sclerosis provides a clear and concise up-to-date overview of the scientific literature on the various theories of MS pathogenesis. Covering the main elements of scientific research into multiple sclerosis, the book contains chapters on the neuropathology of the disease as well as an account of the most extensively used animal model experimental autoimmune encephalomyelitis. The book contains chapters regarding the role of viruses in the development of multiple sclerosis. Viruses have long been implicated and chapters on animal models based on virus infection, as well as their possible role in the etiology of MS, are included. Of interest to MS researchers, the book is written to also be of value to postgraduate and medical students. |
| case study multiple sclerosis: Polymicrobial Diseases Kim A. Brogden, Janet M. Guthmiller, 2002 Polymicrobial diseases, those involving more than one etiologic agent, are more common than is generally realized and include respiratory diseases, gastroenteritis, conjunctivitis, keratitis, hepatitis, periodontal diseases, multiple sclerosis, genital infections, intra -- abdominal infections, and pertussis. |
| case study multiple sclerosis: Neurodegeneration in Multiple Sclerosis M. Filippi, M. Rovaris, G. Comi, 2008-02-01 Written by world-renowned scientists, the volume provides a state-of-the-art on the most recent MRI techniques related to MS, and it is an indispensable tool for all those working in this field. The context in which this book exists is that there is an increasing perception that modern MR methodologies should be more extensively employed in clinical trials to derive innovative information. |
| case study multiple sclerosis: Multiple Sclerosis and Related Disorders Robert J. Fox, MD, Alexander D. Rae-Grant, MD, Francois Bethoux, MD, 2018-08-28 Revised and updated second edition of Multiple Sclerosis and Related Disorders: Clinical Guide to Diagnosis, Medical Management, and Rehabilitation, the only comprehensive but practical source of core information on multiple sclerosis and other demyelinating disorders. Intended as a ready reference for clinicians who provide ongoing care to MS patients, this book combines evidence-based science with experience-based guidance to present current standards and management protocols from leading MS centers. Beginning with the scientific underpinnings of MS for clinicians, the book proceeds through diagnosis, including initial symptoms, diagnostic criteria and classification, imaging, and differential diagnosis, and onto approved treatments for the various MS types and emerging therapies. Later parts of the book discuss symptom management and rehabilitation with chapters focusing on specific side effects, along with considerations for special populations, comorbidities, societal and family issues, and related autoimmune disorders that are often mistaken for MS. Throughout, chapters include lists of Key Points both for clinicians and for patients and families, and management pearls are boxed for quick reference and clinical utility. Illustrations, tables, algorithms, assessment scales, and up-to-date MRI imaging enrich the text, making this a wide-ranging clinical reference for all members of the MS care team. New to the Second Edition: Includes summary recommendations from new AAN practice guidelines for use of DMTs All chapters updated to reflect the latest literature and diagnostic criteria Five entirely new chapters added to expand coverage of treatment, rehabilitation and symptom management, and special issues related to MS Treatment section has been completely revised to better capture current approaches to disease modifying therapies, with separate chapters devoted to injection and oral therapies, infusion therapies, and treatments for progressive forms of MS Related autoimmune diseases section significantly expanded to include transverse myelitis, autoimmune encephalitis, and neurosarcoidosis |
| case study multiple sclerosis: Case Studies in Immunology Raif Geha, FRED Rosen, 2010-07-29 This book presents case histories to illustrate in a clinical context essential points about the mechanisms of immunity. It includes cases that illustrate both recently discovered genetic immunodeficiencies and some more familiar and common diseases with interesting immunology. |
| case study multiple sclerosis: Clinical Cases in Uveitis E-Book Harpal Sandhu, Henry J. Kaplan, 2020-12-09 Intraocular inflammation is particularly difficult to diagnose and treat, often resembling a complex puzzle of patient history, symptoms, imaging, and laboratory test results. Clinical Cases in Uveitis: Differential Diagnosis and Management is a unique, case-based resource designed to help you navigate the range of challenging manifestations and presentations that often mimic other diseases. More than 90 real-world uveitis cases are presented in a highly templated, easy-to-follow format, along with step-by-step guidance on the right patient questions, assessment, differential diagnosis, testing, management, and follow-up care. - Provides a variety of patient presentations and scenarios and unique clinical situations that mirror day-to-day practice. - Covers current diagnostic imaging modalities, including optical coherence tomography (OCT), optical coherence tomography angiography, fluorescein angiography (FA), and indocyanine green angiography (ICG). - Features diagnostic and management algorithms that assist in differential diagnosis and decision making for even the most complex cases, including those in which the patient does not improve as expected, prompting a reassessment of diagnosis and management. - Contains approximately 250 high-quality images, including color anterior segment photographs, color fundus photographs, OCT images, and angiograms. - Discusses distinguishing infectious from non-infectious inflammation; when and how to start systemic immunosuppressive therapy; diagnostic criteria and management of white dot syndromes; pediatric uveitis; masquerade syndromes, including inherited retinal degenerations, malignancies, and paraneoplastic syndromes; and much more. - Includes the authors' specific thought processes and approach in particularly challenging cases. - An excellent resource and study tool for ophthalmology residents and fellows, those studying for oral boards, general ophthalmologists, retina specialists, and more. |
| case study multiple sclerosis: Multiple Sclerosis Sharon Warren, 2001 As the primary neurological disorder of young adults, multiple sclerosis is a significant health problem. While its basis is well known, the etiology of the disease remains to be elucidated. This text provides an overview of this field. |
| case study multiple sclerosis: Moderate to Severe Psoriasis John Koo, Jashin Wu, Alice Gottlieb, Ethan Levin, Argentina Leon, 2014-03-18 Written by experts in the dermatology field, this new fourth edition of Moderate-to-Severe Psoriasis discusses the current use of biologics and other pharmacologic and phototherapy treatments for moderate-to-severe psoriasis. Illustrated with high quality color figures, this standalone text emphasizes safe and effective treatments for the psoriasis |
| case study multiple sclerosis: Primary Progressive Multiple Sclerosis M. Filippi, G. Comi, 2012-12-06 Why are there no effective treatments for my condition? Why do researchers exclude patients with primary progressive multiple sclerosis from enrolling in clinical trials? Please let me know if you hear of studies that I might be allowed to enter or treatments that I could try for my condition. Thus, in recent years, the sad lament of the patient with primary progressive MS (PPMS). This variant, often in the guise of a chronic progressive myelopathy or, less commonly, progressive cerebellar or bulbar dysfunction, usually responds poorly to corticosteroids and rarely seems to benefit to a significant degree from intensive immunosuppressive treatments. In recent years, most randomized clin ical trials have excluded PPMS patients on two counts. Clinical worsening devel ops slowly in PPMS and may not be recognized during the course of a 2-or 3-year trial even in untreated control patients. This factor alone adds to the potential for a type 2 error or, at the very least, inflates the sample size and duration of the trial. In addition, there is mounting evidence that progressive axonal degeneration and neuronal loss (rather than active, recurrent inflammation) may be important components of the pathology in this form of the disease. Although contemporary trials are evaluating whether PPMS patients may benefit from treatment with the ~-interferons and glatiramer acetate, preliminary, uncontrolled clinical experi ence suggests that the results may not be dramatic. |
| case study multiple sclerosis: The Lancet Handbook of Treatment in Neurology Charles Warlow, 2006 This is not a book on how to make a diagnosis, but rather starts from the point of diagnosis and covers all the main neurological conditions as such as stroke, Parkinson's disease, epilepsy and migraine well as some of the rarer conditions such as Wilson's disease showing which treatments are evidence-based but also describing those which at present need more trials. Each condition is described in the following way: definition, cause, frequency, and prognosis. Written by expert contributors, this book describes the treatment that neurologists are responsible for, indicates when to refer, shows complications of treatment, as well as drug interactions. A quick-reference pocket guide Evidence-based treatment described Adverse effects of treatment mentioned along with their likelihood Advice given on when to refer Drug treatments interactions, costs, dosages are covered extensively |
| case study multiple sclerosis: Neurologic Rehabilitation: Neuroscience and Neuroplasticity in Physical Therapy Practice (EB) Deborah S. Nichols Larsen, Deborah K. Kegelmeyer, John A. Buford, Anne D. Kloos, Jill C. Heathcock, D. Michele Basso, 2015-11-22 A full-color neuroscience text that skillfully integrates neuromuscular skeletal content Covers both pediatric and adult issues Beautiful full-color presentation with numerous images Neurorehabilitation in Physical Therapy delivers comprehensive coverage of the structure and function of the human nervous system. It also discusses normal motor development and motor control, as well as common treatment techniques in physical therapy. In order to be engaging to students, cases open each chapter, with questions about those cases appearing throughout the chapter. The text includes numerous tables, flow charts, illustrations, and multiple-choice board-style review questions and is enhanced by a roster of world-renowned clinical contributors. |
| case study multiple sclerosis: The Roy Adaptation Model Callista Roy, Heather A. Andrews, 1999 Compact and consistent, this book focuses on the essentials of nursing practice and theory while integrating the conceptual framework of the Model into contemporary practice. Standardized nursing NANDA diagnoses are used consistently throughout the book. |
| case study multiple sclerosis: Neurologic Differential Diagnosis Marco Mumenthaler, 1992 This second edition of Neurologic Differential Diagnosis brings together clinical neurologic diagnosis with the recent addition of non-invasive neurodiagnostic tests. The combination makes for an economical approach by the neurologist in his attempt to give the patient the best in patient care. |
| case study multiple sclerosis: Healing Touch Dorothea Hover-Kramer, 1996 On the leading edge of the holistic approach to healing, this comprehensive guide discusses the concepts, techniques, and applications of energy-based healing. |
| case study multiple sclerosis: Neurology Case Studies Randolph W. Evans, 2006 The use of case studies is vital as an educational technique in medicine, particularly to clinicians, because it illustrates current medical methodology and values. This issue includes case studies in all the major subspecialties within neurology such as headache, multiple sclerosis, sleep, dementia, movement disorders, neck and low back pain, epilepsy, cerebrovascular disease, neuro-ophthalmology, syncope, and critical care. |
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