| could the tuskegee syphilis study be conducted today: Tuskegee's Truths Susan M. Reverby, 2012-12-01 Between 1932 and 1972, approximately six hundred African American men in Alabama served as unwitting guinea pigs in what is now considered one of the worst examples of arrogance, racism, and duplicity in American medical research--the Tuskegee syphilis study. Told they were being treated for bad blood, the nearly four hundred men with late-stage syphilis and two hundred disease-free men who served as controls were kept away from appropriate treatment and plied instead with placebos, nursing visits, and the promise of decent burials. Despite the publication of more than a dozen reports in respected medical and public health journals, the study continued for forty years, until extensive media coverage finally brought the experiment to wider public knowledge and forced its end. This edited volume gathers articles, contemporary newspaper accounts, selections from reports and letters, reconsiderations of the study by many of its principal actors, and works of fiction, drama, and poetry to tell the Tuskegee story as never before. Together, these pieces illuminate the ethical issues at play from a remarkable breadth of perspectives and offer an unparalleled look at how the study has been understood over time. |
| could the tuskegee syphilis study be conducted today: Bad Blood James Howard Jones, 1981 Story of the Tuskegee experiment where gvoernment doctors infected black patients with syphillis. |
| could the tuskegee syphilis study be conducted today: Bad Blood James H. Jones, 1993 The modern classic of race and medicine updated with an additional chapter on the Tuskegee experiment's legacy in the age of AIDS. |
| could the tuskegee syphilis study be conducted today: The Unfortunate Experiment Sandra Coney, 1988 In 1984 the medical journal Obstetrics and Gynecology published a paper that would initiate an investigation into one of the greatest medical scandals of the late twentieth century. Titled The Invasive Potential of Carcinoma in Situ of the Cervix, it discussed the results of an experiment that had been run at the National Women’s Hospital in Auckland, New Zealand, since 1955. The experiment looked at the natural history of cervical carcinoma in situ (CIS) – in other words, what happens if no treatment is initiated in a condition suspected (when the experiment began) to lead to cervical cancer. The paper divided participants into two groups, one that had negative results after biopsy or treatment, and one smaller group that continued to test positive. This second group had a significant rate of cervical cancer; some of these women were followed for twenty-five years without treatment, and in only 5% did the disease spontaneously resolve. For the other 95%, outcomes ranged from positive but localised results to metastatic disease and death. The authors said these results were in contrast with other, earlier papers about the experiment. After much research, Sandra Coney, one-time editor of a NZ feminist magazine, and Phyllida Bunkle, a women’s studies lecturer, wrote an article about the experiment, exposing the unauthorised research performed by one prominent gynaecologist in support of his belief that CIS was not associated with cervical cancer. Professor Herbert Green, a physician of considerable influence and power throughout New Zealand, persisted in his belief despite increasingly convincing proof of a progressive connection between the two conditions, never sought permission from his patients, or even told them what he was doing. |
| could the tuskegee syphilis study be conducted today: The Tuskegee Syphilis Study Fred D. Gray, 2013-01-01 In 1932, the U.S. Public Health Service recruited 623 African American men from Macon County, Alabama, for a study of the effects of untreated syphilis in the Negro male. For the next 40 years -- even after the development of penicillin, the cure for syphilis -- these men were denied medical care for this potentially fatal disease. The Tuskegee Syphilis Study was exposed in 1972, and in 1975 the government settled a lawsuit but stopped short of admitting wrongdoing. In 1997, President Bill Clinton welcomed five of the Study survivors to the White House and, on behalf of the nation, officially apologized for an experiment he described as wrongful and racist. In this book, the attorney for the men, Fred D. Gray, describes the background of the Study, the investigation and the lawsuit, the events leading up to the Presidential apology, and the ongoing efforts to see that out of this painful and tragic episode of American history comes lasting good. |
| could the tuskegee syphilis study be conducted today: Medical Apartheid Harriet A. Washington, 2008-01-08 NATIONAL BOOK CRITICS CIRCLE AWARD WINNER • The first full history of Black America’s shocking mistreatment as unwilling and unwitting experimental subjects at the hands of the medical establishment. No one concerned with issues of public health and racial justice can afford not to read this masterful book. [Washington] has unearthed a shocking amount of information and shaped it into a riveting, carefully documented book. —New York Times From the era of slavery to the present day, starting with the earliest encounters between Black Americans and Western medical researchers and the racist pseudoscience that resulted, Medical Apartheid details the ways both slaves and freedmen were used in hospitals for experiments conducted without their knowledge—a tradition that continues today within some black populations. It reveals how Blacks have historically been prey to grave-robbing as well as unauthorized autopsies and dissections. Moving into the twentieth century, it shows how the pseudoscience of eugenics and social Darwinism was used to justify experimental exploitation and shoddy medical treatment of Blacks. Shocking new details about the government’s notorious Tuskegee experiment are revealed, as are similar, less-well-known medical atrocities conducted by the government, the armed forces, prisons, and private institutions. The product of years of prodigious research into medical journals and experimental reports long undisturbed, Medical Apartheid reveals the hidden underbelly of scientific research and makes possible, for the first time, an understanding of the roots of the African American health deficit. At last, it provides the fullest possible context for comprehending the behavioral fallout that has caused Black Americans to view researchers—and indeed the whole medical establishment—with such deep distrust. |
| could the tuskegee syphilis study be conducted today: The Belmont Report United States. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research, 1978 |
| could the tuskegee syphilis study be conducted today: Chronicling the Tuskegee Syphilis Study Obiora N. Anekwe, Ed.d., Ejinkonye C. Anekwe, Ph.d., 2013-12-19 In 1972, the longest clinical trial in U.S. medical research history abruptly ended. Known to many as the Tuskegee Syphilis Study, this experiment has been studied by ethicists around the world. It has presented challenges in how to conduct ethical research without harming human subjects. Chronicling the Tuskegee Syphilis Study is a book that provides essays, commentaries, academic writings, and other documented works in order to give multiple insights and solutions to resolving dilemmas related to unethical clinical trials such as Tuskegee. It gives a perspective of the Tuskegee Syphilis Study from the unique vantage point of two brothers born in the hospital where the experiments took place. Join us as we share the story of Tuskegee with you. |
| could the tuskegee syphilis study be conducted today: Examining Tuskegee Susan Reverby, 2009 The forty-year Tuskegee Syphilis Study has become the American metaphor for medical racism, government malfeasance, and physician arrogance. The subject of histories, films, rumors, and political slogans, it received an official federal apology f |
| could the tuskegee syphilis study be conducted today: The Search for the Legacy of the USPHS Syphilis Study at Tuskegee Ralph V. Katz, Rueben C. Warren, 2011 The Search for the Legacy of the USPHS Syphilis Study at Tuskegee is a collection of essays that seeks to redefine the legacy of the infamous Tuskegee Syphilis Study in light of recent findings from other scientific studies that challenge the long-standing, widely-held understanding of the study. These essays are written with thoughtful attention to fully integrate the essayists' perspectives on the impact of the study on the lives of Americans today and place the legacy of the study within the evolving picture of racial and ethnic relations in the United States. Each essayist looks through his or her own personal and professional prism to give an account of what constitutes that legacy today. Contributors include the two leading historians of the Tuskeegee Syphilis Study and two former Surgeons General of the United States as well as other prominent scholars from the fields of public health, bioethics, psychology, biostatistics, medicine, dentistry, journalism, medical sociology, medical anthropology, and health disparities research. |
| could the tuskegee syphilis study be conducted today: The Immortal Life of Henrietta Lacks Rebecca Skloot, 2010-02-02 #1 NEW YORK TIMES BESTSELLER • “The story of modern medicine and bioethics—and, indeed, race relations—is refracted beautifully, and movingly.”—Entertainment Weekly NOW A MAJOR MOTION PICTURE FROM HBO® STARRING OPRAH WINFREY AND ROSE BYRNE • ONE OF THE “MOST INFLUENTIAL” (CNN), “DEFINING” (LITHUB), AND “BEST” (THE PHILADELPHIA INQUIRER) BOOKS OF THE DECADE • ONE OF ESSENCE’S 50 MOST IMPACTFUL BLACK BOOKS OF THE PAST 50 YEARS • WINNER OF THE CHICAGO TRIBUNE HEARTLAND PRIZE FOR NONFICTION NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The New York Times Book Review • Entertainment Weekly • O: The Oprah Magazine • NPR • Financial Times • New York • Independent (U.K.) • Times (U.K.) • Publishers Weekly • Library Journal • Kirkus Reviews • Booklist • Globe and Mail Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than sixty years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave. Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family—past and present—is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of. Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah. Deborah was consumed with questions: Had scientists cloned her mother? Had they killed her to harvest her cells? And if her mother was so important to medicine, why couldn’t her children afford health insurance? Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences. |
| could the tuskegee syphilis study be conducted today: Health and Humanity Karen Kruse Thomas, 2016-07 The mid-twentieth-century evolution of the Johns Hopkins School of Public Health. Between 1935 and 1985, the nascent public health profession developed scientific evidence and practical know-how to prevent death on an unprecedented scale. Thanks to public health workers, life expectancy rose rapidly as generations grew up free from the scourges of smallpox, typhoid, and syphilis. In Health and Humanity, Karen Kruse Thomas offers a thorough account of the growth of academic public health in the United States through the prism of the oldest and largest independent school of public health in the world. Thomas follows the transformation of the Johns Hopkins School of Hygiene and Public Health (JHSPH), now known as the Bloomberg School of Public Health, from a small, private institute devoted to doctoral training and tropical disease research into a leading global educator and innovator in fields from biostatistics to mental health to pathobiology. A provocative, wide-ranging account of how midcentury public health leveraged federal grants and anti-Communist fears to build the powerful institutional networks behind the health programs of the CDC, WHO, and USAID, the book traces how Johns Hopkins helped public health take center stage during the scientific research boom triggered by World War II. It also examines the influence of politics on JHSPH, the school’s transition to federal grant funding, the globalization of public health in response to hot and cold war influences, and the expansion of the school’s teaching program to encompass social science as well as lab science. Revealing how faculty members urged foreign policy makers to include saving lives in their strategy of “winning hearts and minds,” Thomas argues that the growth of chronic disease and the loss of Rockefeller funds moved the JHSPH toward international research funded by the federal government, creating a situation in which it was sometimes easier for the school to improve the health of populations in India and Turkey than on its own doorstep in East Baltimore. Health and Humanity is a comprehensive account of the ways that JHSPH has influenced the practice, pedagogy, and especially our very understanding of public health on both global and local scales. |
| could the tuskegee syphilis study be conducted today: Subjected to Science Susan E. Lederer, 1997-11-07 Susan Lederer provides the first full-length history of early biomedical research with human subjects. Lederer offers detailed accounts of experiments conducted on both healthy and unhealthy men, women, and children, during the period from 1890 to 1940, including yellow fever experiments, Udo Wile's dental drill experiments on insane patients, and Hideyo Noguchi's syphilis experiments. |
| could the tuskegee syphilis study be conducted today: "Ethically Impossible" , 2011 In response to a request by President Barak Obama on November 24, 2010, the Presidential Commission for the Study of Bioethical Issues oversaw a thorough fact-finding investigation into the specifics of the U.S. Public Health Service-led studies in Guatemala involving the intentional exposure and infection of vulnerable populations. Following a nine-month intensive investigation, the Commission has concluded that the Guatemala experiments involved gross violations of ethics as judged against both the standards of today and the researchers' own understanding of applicable contemporaneous practices. It is the Commission's firm belief that many of the actions undertaken in Guatemala were especially egregious moral wrongs because many of the individuals involved held positions of public institutional responsibility. The best thing we can do as a country when faced with a dark chapter is to bring it to light. The Commission has worked hard to provide an unvarnished ethical analysis to both honor the victims and make sure events such as these never happen again. |
| could the tuskegee syphilis study be conducted today: Women and Health Research Institute of Medicine, Committee on Ethical and Legal Issues Relating to the Inclusion of Women in Clinical Studies, 1994-02-01 In the nineteenth century some scientists argued that women should not be educated because thinking would use energy needed by the uterus for reproduction. The proof? Educated women had a lower birth rate. Today's researchers can only shake their heads at such reasoning. Yet professional journals and the popular press are increasingly criticizing medical research for ignoring women's health issues. Women and Health Research examines the facts behind the public's perceptions about women participating as subjects in medical research. With the goal of increasing researchers' awareness of this important topic, the book explores issues related to maintaining justice (in its ethical sense) in clinical studies. Leading experts present general principles for the ethical conduct of research on womenâ€principles that are especially important in the light of recent changes in federal policy on the inclusion of women in clinical research. Women and Health Research documents the historical shift from a paternalistic approach by researchers toward women and a disproportionate reliance on certain groups for research to one that emphasizes proper access for women as subjects in clinical studies in order to ensure that women receive the benefits of research. The book addresses present-day challenges to equity in four areas: Scientificâ€Do practical aspects of scientific research work at cross-purposes to gender equity? Focusing on drug trials, the authors identify rationales for excluding people from research based on demographics. Social and Ethicalâ€The authors offer compelling discussions on subjectivity in science, the evidence for male bias, and issues related to race and ethnicity, as well as the recruitment, retention, and protection of research participants. Legalâ€Women and Health Research reviews federal research policies that affect the inclusion of women and evaluates the basis for researchers' fears about liability, citing court cases. Riskâ€The authors focus on risks to reproduction and offspring in clinical drug trials, exploring how risks can be identified for study participants, who should make the assessment of risk and benefit for participation in a clinical study, and how legal implications could be addressed. This landmark study will be of immediate use to the research community, policymakers, women's health advocates, attorneys, and individuals. |
| could the tuskegee syphilis study be conducted today: National Negro Health Week ... , 1934 |
| could the tuskegee syphilis study be conducted today: The Oxford Textbook of Clinical Research Ethics Ezekiel J. Emanuel, Christine C. Grady, Robert A. Crouch, Reidar K. Lie, Franklin G. Miller, David D. Wendler, 2011-02 The Oxford Textbook of Clinical Research Ethics is the first comprehensive and systematic reference on clinical research ethics. Under the editorship of experts from the U.S. National Institutes of Health of the United States, the book's 73 chapters offer a wide-ranging and systematic examination of all aspects of research with human beings. Considering the historical triumphs of research as well as its tragedies, the textbook provides a framework for analyzing the ethical aspects of research studies with human beings. Through both conceptual analysis and systematic reviews of empirical data, the contributors examine issues ranging from scientific validity, fair subject selection, risk benefit ratio, independent review, and informed consent to focused consideration of international research ethics, conflicts of interests, and other aspects of responsible conduct of research. The editors of The Oxford Textbook of Clinical Research Ethics offer a work that critically assesses and advances scholarship in the field of human subjects research. Comprehensive in scope and depth, this book will be a crucial resource for researchers in the medical sciences, as well as teachers and students. |
| could the tuskegee syphilis study be conducted today: Research Ethics Kenneth D. Pimple, 2017-05-15 This volume includes more than 40 important articles on integrity and misconduct, biomedical research, the social and disciplinary contexts of science, research in the social sciences, the social responsibility of science and scientists, and other core issues in research ethics. A new introduction by the editor places these articles in their historical and conceptual context. The volume provides a rich library of resources, ideas and challenges in the ethics of research for any scholar concerned with such issues. |
| could the tuskegee syphilis study be conducted today: Conducting Biosocial Surveys National Research Council, Division of Behavioral and Social Sciences and Education, Committee on Population, Committee on National Statistics, Panel on Collecting, Storing, Accessing, and Protecting Biological Specimens and Biodata in Social Surveys, 2010-10-02 Recent years have seen a growing tendency for social scientists to collect biological specimens such as blood, urine, and saliva as part of large-scale household surveys. By combining biological and social data, scientists are opening up new fields of inquiry and are able for the first time to address many new questions and connections. But including biospecimens in social surveys also adds a great deal of complexity and cost to the investigator's task. Along with the usual concerns about informed consent, privacy issues, and the best ways to collect, store, and share data, researchers now face a variety of issues that are much less familiar or that appear in a new light. In particular, collecting and storing human biological materials for use in social science research raises additional legal, ethical, and social issues, as well as practical issues related to the storage, retrieval, and sharing of data. For example, acquiring biological data and linking them to social science databases requires a more complex informed consent process, the development of a biorepository, the establishment of data sharing policies, and the creation of a process for deciding how the data are going to be shared and used for secondary analysis-all of which add cost to a survey and require additional time and attention from the investigators. These issues also are likely to be unfamiliar to social scientists who have not worked with biological specimens in the past. Adding to the attraction of collecting biospecimens but also to the complexity of sharing and protecting the data is the fact that this is an era of incredibly rapid gains in our understanding of complex biological and physiological phenomena. Thus the tradeoffs between the risks and opportunities of expanding access to research data are constantly changing. Conducting Biosocial Surveys offers findings and recommendations concerning the best approaches to the collection, storage, use, and sharing of biospecimens gathered in social science surveys and the digital representations of biological data derived therefrom. It is aimed at researchers interested in carrying out such surveys, their institutions, and their funding agencies. |
| could the tuskegee syphilis study be conducted today: Soldaten - On Fighting, Killing and Dying Sonke Neitzel, Harald Welzer, 2012-09-25 In November 2001, as the world still reeled from the attack on the Twin Towers, German historian Sonke Neitzel discovered an extraordinary cache of documents from the Second World War. The documents were the transcripts of German prisoners of war talking among themselves in prisoner of war camps, and secretly recorded by the allies. In these apparently private conversations the soldiers talked freely and openly about their hopes and fears, their concerns and their day-to-day lives. With a banality and ease which to the modern reader can appear shocking, they also talked about the horrors of war -- about rape, death and killing. Sonke Neitzel shared the material with renowned and bestselling psychologist Harald Wezler and they set about trying to make sense of the vast piles of documents, the hours of transcripts. The result is SOLDATEN, a landmark book which will change the way we look at soldiers and war, and is as relevant to our modern conflicts in Iraq and Afghanistan as it was to the soldiers of the German Army in 1945. Published to huge acclaim and controversy in Germany it was a number one bestseller there and reignited the debate about the banality of evil under the Nazi regime. |
| could the tuskegee syphilis study be conducted today: Ethical Considerations for Research on Housing-Related Health Hazards Involving Children Institute of Medicine, National Research Council, Division of Behavioral and Social Sciences and Education, Board on Children, Youth, and Families, Committee on Ethical Issues in Housing-Related Health Hazard Research Involving Children, Youth, and Families, 2005-11-10 Ethical Considerations for Research on Housing-Related Health Hazards Involving Children explores the ethical issues posed when conducting research designed to identify, understand, or ameliorate housing-related health hazards among children. Such research involves children as subjects and is conducted in the home and in communities. It is often conducted with children in low-income families given the disproportionate prevalence of housing-related conditions such as lead poisoning, asthma, and fatal injuries among these children. This book emphasizes five key elements to address the particular ethical concerns raised by these characteristics: involving the affected community in the research and responding to their concerns; ensuring that parents understand the essential elements of the research; adopting uniform federal guidelines for such research by all sponsors (Subpart D of 45 CFR 46); providing guidance on key terms in the regulations; and viewing research oversight as a system with important roles for researchers, IRBs and their research institutions, sponsors and regulators of research, and the community. |
| could the tuskegee syphilis study be conducted today: Dark Medicine William R. LaFleur, Gernot Böhme, Susumu Shimazono, 2008-07-17 This collection of essays looks at the dark medical research conducted during and after World War II. Contributors describe this research, how it was brought to light, and the rationalisations of those who perpetrated and benefited from it. |
| could the tuskegee syphilis study be conducted today: The Ethics of Social Research Roger Homan, 1991 This book examines the traditional areas of ethical concern such as privacy, confidentiality, professional controls and the use of covet methods. While it recognises the case against deception and covertness, it also challenges the assumption that open methods are always more virtuous and suggest the working out of a rationale of covert methods in ethical terms.--BOOK COVER. |
| could the tuskegee syphilis study be conducted today: The Power of Experiments Michael Luca, Max H. Bazerman, 2021-03-02 How tech companies like Google, Airbnb, StubHub, and Facebook learn from experiments in our data-driven world—an excellent primer on experimental and behavioral economics Have you logged into Facebook recently? Searched for something on Google? Chosen a movie on Netflix? If so, you've probably been an unwitting participant in a variety of experiments—also known as randomized controlled trials—designed to test the impact of different online experiences. Once an esoteric tool for academic research, the randomized controlled trial has gone mainstream. No tech company worth its salt (or its share price) would dare make major changes to its platform without first running experiments to understand how they would influence user behavior. In this book, Michael Luca and Max Bazerman explain the importance of experiments for decision making in a data-driven world. Luca and Bazerman describe the central role experiments play in the tech sector, drawing lessons and best practices from the experiences of such companies as StubHub, Alibaba, and Uber. Successful experiments can save companies money—eBay, for example, discovered how to cut $50 million from its yearly advertising budget—or bring to light something previously ignored, as when Airbnb was forced to confront rampant discrimination by its hosts. Moving beyond tech, Luca and Bazerman consider experimenting for the social good—different ways that governments are using experiments to influence or “nudge” behavior ranging from voter apathy to school absenteeism. Experiments, they argue, are part of any leader's toolkit. With this book, readers can become part of “the experimental revolution.” |
| could the tuskegee syphilis study be conducted today: Ethics and Regulation of Clinical Research Robert J. Levine, 1988-01-01 The use of human subjects in medical and scientific research has given rise to troubling ethical questions. How should human subjects be selected for experiments? What should they be told about the research in which they are involved? How can their privacy be protected? When is it permissible to deceive them? How do we deal with subjects such as children, fetuses, and the mentally infirm, for whom informed consent is impossible? In this book, Dr. Robert J. Levine reviews federal regulations, ethical analysis, and case studies in an attempt to answer these questions. His book is an essential reference for everyone--members of institutional review boards, scientists, philosophers, lawyers--addressing the ethical issues involved. [Levine's] experience as a clinician, IRB chairman, writer and editor of a journal devoted exclusively to issues faced by IRBS makes him uniquely qualified to bring together the legal, ethical, and practical dimensions. . . [The book] is sophisticated but readable. . . [and] should be on every IRB administrator's desk and in every medical ethics library.--Norman Fost, M.D., The New England Journal of Medicine Levine. . . is one of the foremost historians of contemporary clinical science. . . . His book is at once a guide to primary sources for the history of clinical research in the late twentieth century and a pioneering secondary source about that history.--Daniel M. Fox, Bulletin of the History of Medicine You will be charmed by the [book's] elegance and lucidity and. . . persuaded of its relevance to doctors in any country.--Alex Paton, British Medical Journal Should be of wide interest to those keen to see advances in medical research brought into general medical practice.--Gilbert Omenn, Issues in Science and Technology |
| could the tuskegee syphilis study be conducted today: Ethical Considerations for Research Involving Prisoners Committee on Ethical Considerations for Revisions to DHHS Regulations for Protection of Prisoners Involved in Research, Board on Health Sciences Policy, Institute of Medicine, 2007-01-22 In the past 30 years, the population of prisoners in the United States has expanded almost 5-fold, correctional facilities are increasingly overcrowded, and more of the country's disadvantaged populations—racial minorities, women, people with mental illness, and people with communicable diseases such as HIV/AIDS, hepatitis C, and tuberculosis—are under correctional supervision. Because prisoners face restrictions on liberty and autonomy, have limited privacy, and often receive inadequate health care, they require specific protections when involved in research, particularly in today's correctional settings. Given these issues, the Department of Health and Human Services' Office for Human Research Protections commissioned the Institute of Medicine to review the ethical considerations regarding research involving prisoners. The resulting analysis contained in this book, Ethical Considerations for Research Involving Prisoners, emphasizes five broad actions to provide prisoners involved in research with critically important protections: • expand the definition of prisoner; • ensure universally and consistently applied standards of protection; • shift from a category-based to a risk-benefit approach to research review; • update the ethical framework to include collaborative responsibility; and • enhance systematic oversight of research involving prisoners. |
| could the tuskegee syphilis study be conducted today: Handbook of Neuroemergency Clinical Trials Brett E. Skolnick, Wayne M. Alves, 2017-11-13 Handbook of Neuroemergency Clinical Trials, Second Edition, focuses on the practice of clinical trials in acute neuroscience populations, or what have been called neuroemergencies. Neuroemergencies are complex, life-threatening diseases and disorders, often with devastating consequences, including death or disability. The overall costs are staggering in terms of annual incidence and costs associated with treatment and survival, yet despite their significance as public health issues, there are few drugs and devices available for definitive treatment. The book focuses on novel therapies and the unique challenges their intended targets pose for the design and analysis of clinical trials. This volume provides neurologists, neuroscientists, and drug developers with a more complete understanding of the scientific and medical issues of relevance in designing and initiating clinical development plans for novel drugs intended for acute neuroscience populations. The editors provide the best understanding of the pitfalls associated with acute CNS drug development and the best information on how to approach and solve issues that have plagued drug development. - Presents a comprehensive overview on clinical trials and drug development challenges in acute neuroscience populations - Provides neurologists, neuroscientists and drug developers with a complete understanding of scientific and medical issues related to designing clinical trials - Edited by leaders in the field who have designed and managed over 50 neuroemergency clinical trials |
| could the tuskegee syphilis study be conducted today: Community- Based Health Research Daniel S. Blumenthal, Ralph J. DiClemente, PhD, 2004 This book identifies key concepts of successful community-based research beyond the aspect of location, including prevention focus, population-centered partnerships, multidisciplinary cooperation, and cultural competency. Lessons from the Tuskegee Syphilis Study and case studies on HIV/AIDS prevention and cardiovascular risk reduction illustrate the application of research methods with both positive and negative outcomes. For Further Information, Please Click Here! |
| could the tuskegee syphilis study be conducted today: Miss Evers' Boys David Feldshuh, 1995 THE STORY: In an effort to get medical help for Alabama tenant farmers, their nurse, Miss Evers, convinces them to join a government study to treat venereal disease. When the money runs out, Nurse Evers is faced with a difficult decision: to tell t |
| could the tuskegee syphilis study be conducted today: Introduction to Sociology 2e Nathan J. Keirns, Heather Griffiths, Eric Strayer, Susan Cody-Rydzewski, Gail Scaramuzzo, Sally Vyain, Tommy Sadler, Jeff D. Bry, Faye Jones, 2015-03-17 This text is intended for a one-semester introductory course.--Page 1. |
| could the tuskegee syphilis study be conducted today: Beyond the HIPAA Privacy Rule Institute of Medicine, Board on Health Care Services, Board on Health Sciences Policy, Committee on Health Research and the Privacy of Health Information: The HIPAA Privacy Rule, 2009-03-24 In the realm of health care, privacy protections are needed to preserve patients' dignity and prevent possible harms. Ten years ago, to address these concerns as well as set guidelines for ethical health research, Congress called for a set of federal standards now known as the HIPAA Privacy Rule. In its 2009 report, Beyond the HIPAA Privacy Rule: Enhancing Privacy, Improving Health Through Research, the Institute of Medicine's Committee on Health Research and the Privacy of Health Information concludes that the HIPAA Privacy Rule does not protect privacy as well as it should, and that it impedes important health research. |
| could the tuskegee syphilis study be conducted today: Sharing Clinical Trial Data Institute of Medicine, Board on Health Sciences Policy, Committee on Strategies for Responsible Sharing of Clinical Trial Data, 2015-04-20 Data sharing can accelerate new discoveries by avoiding duplicative trials, stimulating new ideas for research, and enabling the maximal scientific knowledge and benefits to be gained from the efforts of clinical trial participants and investigators. At the same time, sharing clinical trial data presents risks, burdens, and challenges. These include the need to protect the privacy and honor the consent of clinical trial participants; safeguard the legitimate economic interests of sponsors; and guard against invalid secondary analyses, which could undermine trust in clinical trials or otherwise harm public health. Sharing Clinical Trial Data presents activities and strategies for the responsible sharing of clinical trial data. With the goal of increasing scientific knowledge to lead to better therapies for patients, this book identifies guiding principles and makes recommendations to maximize the benefits and minimize risks. This report offers guidance on the types of clinical trial data available at different points in the process, the points in the process at which each type of data should be shared, methods for sharing data, what groups should have access to data, and future knowledge and infrastructure needs. Responsible sharing of clinical trial data will allow other investigators to replicate published findings and carry out additional analyses, strengthen the evidence base for regulatory and clinical decisions, and increase the scientific knowledge gained from investments by the funders of clinical trials. The recommendations of Sharing Clinical Trial Data will be useful both now and well into the future as improved sharing of data leads to a stronger evidence base for treatment. This book will be of interest to stakeholders across the spectrum of research-from funders, to researchers, to journals, to physicians, and ultimately, to patients. |
| could the tuskegee syphilis study be conducted today: Tearoom Trade Laud Humphreys, 2017-07-12 From the time of its first publication, 'Tearoom Trade' engendered controversy. It was also accorded an unusual amount of praise for a first book on a marginal, intentionally self-effacing population by a previously unknown sociologist. The book was quickly recognized as an important, imaginative, and useful contribution to our understanding of deviant sexual activity. Describing impersonal, anonymous sexual encounters in public restrooms—tearooms in the argot—the book explored the behavior of men whose closet homosexuality was kept from their families and neighbors. By posing as an initiate, the author was able to engage in systematic observation of homosexual acts in public settings, and later to develop a more complete picture of those involved by interviewing them in their homes, again without revealing their unwitting participation in his study. This enlarged edition of 'Tearoom Trade' includes the original text, together with a retrospect, written by Nicholas von Hoffman, Irving Louis Horowitz, Lee Rainwater, Donald P. Warwick, and Myron Glazer. The material added includes a perspective on the social scientist at work and the ethical problems to which that work may give rise, along with debate by the book's initial critics and proponents. Humphreys added a postscript and his views on the opinion expressed in the retrospect. |
| could the tuskegee syphilis study be conducted today: The Plutonium Files Eileen Welsome, 2010-10-20 When the vast wartime factories of the Manhattan Project began producing plutonium in quantities never before seen on earth, scientists working on the top-secret bomb-building program grew apprehensive. Fearful that plutonium might cause a cancer epidemic among workers and desperate to learn more about what it could do to the human body, the Manhattan Project's medical doctors embarked upon an experiment in which eighteen unsuspecting patients in hospital wards throughout the country were secretly injected with the cancer-causing substance. Most of these patients would go to their graves without ever knowing what had been done to them. Now, in The Plutonium Files, Pulitzer Prize-winning reporter Eileen Welsome reveals for the first time the breadth of the extraordinary fifty-year cover-up surrounding the plutonium injections, as well as the deceitful nature of thousands of other experiments conducted on American citizens in the postwar years. Welsome's remarkable investigation spans the 1930s to the 1990s and draws upon hundreds of newly declassified documents and other primary sources to disclose this shadowy chapter in American history. She gives a voice to such innocents as Helen Hutchison, a young woman who entered a prenatal clinic in Nashville for a routine checkup and was instead given a radioactive cocktail to drink; Gordon Shattuck, one of several boys at a state school for the developmentally disabled in Massachusetts who was fed radioactive oatmeal for breakfast; and Maude Jacobs, a Cincinnati woman suffering from cancer and subjected to an experimental radiation treatment designed to help military planners learn how to win a nuclear war. Welsome also tells the stories of the scientists themselves, many of whom learned the ways of secrecy on the Manhattan Project. Among them are Stafford Warren, a grand figure whose bravado masked a cunning intelligence; Joseph Hamilton, who felt he was immune to the dangers of radiation only to suffer later from a fatal leukemia; and physician Louis Hempelmann, one of the most enthusiastic supporters of the plan to inject humans with potentially carcinogenic doses of plutonium. Hidden discussions of fifty years past are reconstructed here, wherein trusted government officials debated the ethical and legal implications of the experiments, demolishing forever the argument that these studies took place in a less enlightened era. Powered by her groundbreaking reportage and singular narrative gifts, Eileen Welsome has created a work of profound humanity as well as major historical significance. From the Hardcover edition. |
| could the tuskegee syphilis study be conducted today: The Ethics of Research with Human Subjects David B. Resnik, 2018-01-09 This book provides a framework for approaching ethical and policy dilemmas in research with human subjects from the perspective of trust. It explains how trust is important not only between investigators and subjects but also between and among other stakeholders involved in the research enterprise, including research staff, sponsors, institutions, communities, oversight committees, government agencies, and the general public. The book argues that trust should be viewed as a distinct ethical principle for research with human subjects that complements other principles, such as autonomy, beneficence, non-maleficence, and justice. The book applies the principle of trust to numerous issues, including informed consent, confidentiality, risk minimization, risks and benefits, protection of vulnerable subjects, experimental design, research integrity, and research oversight.This work also includes discussions of the history of research involving human subjects, moral theories and principles, contemporary cases, and proposed regulatory reforms. The book is useful for undergraduate and graduate students studying ethical policy issues related to research with human subjects, as well as for scientists and scholars who are interested in thinking about this topic from the perspective of trust. |
| could the tuskegee syphilis study be conducted today: Acres of Skin Allen M. Hornblum, 2013-05-13 At a time of increased interest and renewed shock over the Tuskegee syphilis experiments, Acres of Skin sheds light on yet another dark episode of American medical history. In this disturbing expose, Allen M. Hornblum tells the story of Philadelphia's Holmesburg Prison. |
| could the tuskegee syphilis study be conducted today: Ethical Conduct of Clinical Research Involving Children Institute of Medicine, Board on Health Sciences Policy, Committee on Clinical Research Involving Children, 2004-07-09 In recent decades, advances in biomedical research have helped save or lengthen the lives of children around the world. With improved therapies, child and adolescent mortality rates have decreased significantly in the last half century. Despite these advances, pediatricians and others argue that children have not shared equally with adults in biomedical advances. Even though we want children to benefit from the dramatic and accelerating rate of progress in medical care that has been fueled by scientific research, we do not want to place children at risk of being harmed by participating in clinical studies. Ethical Conduct of Clinical Research Involving Children considers the necessities and challenges of this type of research and reviews the ethical and legal standards for conducting it. It also considers problems with the interpretation and application of these standards and conduct, concluding that while children should not be excluded from potentially beneficial clinical studies, some research that is ethically permissible for adults is not acceptable for children, who usually do not have the legal capacity or maturity to make informed decisions about research participation. The book looks at the need for appropriate pediatric expertise at all stages of the design, review, and conduct of a research project to effectively implement policies to protect children. It argues persuasively that a robust system for protecting human research participants in general is a necessary foundation for protecting child research participants in particular. |
| could the tuskegee syphilis study be conducted today: The Experiment Station , 1888 |
| could the tuskegee syphilis study be conducted today: Oncology Informatics Bradford W. Hesse, David Ahern, Ellen Beckjord, 2016-03-17 Oncology Informatics: Using Health Information Technology to Improve Processes and Outcomes in Cancer Care encapsulates National Cancer Institute-collected evidence into a format that is optimally useful for hospital planners, physicians, researcher, and informaticians alike as they collectively strive to accelerate progress against cancer using informatics tools. This book is a formational guide for turning clinical systems into engines of discovery as well as a translational guide for moving evidence into practice. It meets recommendations from the National Academies of Science to reorient the research portfolio toward providing greater cognitive support for physicians, patients, and their caregivers to improve patient outcomes. Data from systems studies have suggested that oncology and primary care systems are prone to errors of omission, which can lead to fatal consequences downstream. By infusing the best science across disciplines, this book creates new environments of Smart and Connected Health. Oncology Informatics is also a policy guide in an era of extensive reform in healthcare settings, including new incentives for healthcare providers to demonstrate meaningful use of these technologies to improve system safety, engage patients, ensure continuity of care, enable population health, and protect privacy. Oncology Informatics acknowledges this extraordinary turn of events and offers practical guidance for meeting meaningful use requirements in the service of improved cancer care. Anyone who wishes to take full advantage of the health information revolution in oncology to accelerate successes against cancer will find the information in this book valuable. Presents a pragmatic perspective for practitioners and allied health care professionals on how to implement Health I.T. solutions in a way that will minimize disruption while optimizing practice goals Proposes evidence-based guidelines for designers on how to create system interfaces that are easy to use, efficacious, and timesaving Offers insight for researchers into the ways in which informatics tools in oncology can be utilized to shorten the distance between discovery and practice |
| could the tuskegee syphilis study be conducted today: Secret Cures of Slaves Londa Schiebinger, 2017-07-18 “Engaging unique sources . . . Londa Schiebinger untangles the complex relationships between European and local physicians, healers, plants, and slavery.” —François Regourd, Université Paris Nanterre In the natural course of events, humans fall sick and die. The history of medicine bristles with attempts to find new and miraculous remedies, to work with and against nature to restore humans to health and well-being. In this book, Londa Schiebinger examines medicine and human experimentation in the Atlantic World, exploring the circulation of people, disease, plants, and knowledge between Europe, Africa, and the Americas. She traces the development of a colonial medical complex from the 1760s, when a robust experimental culture emerged in the British and French West Indies, to the early 1800s, when debates raged about banning the slave trade and, eventually, slavery itself. Massive mortality among enslaved Africans and European planters, soldiers, and sailors fueled the search for new healing techniques. Amerindian, African, and European knowledges competed to cure diseases emerging from the collision of peoples on newly established, often poorly supplied, plantations. But not all knowledge was equal. Highlighting the violence and fear endemic to colonial struggles, Schiebinger explores aspects of African medicine that were not put to the test, such as Obeah and vodou. This book analyzes how and why specific knowledges were blocked, discredited, or held secret. “In this urgent, probing and visually striking volume, Londa Schiebinger, one of the pioneers of feminist and colonial science studies, shifts our understanding of Enlightenment racial attitudes to the domain of the medical, making a vital contribution to the dynamic new wave of research on science and slavery in the Atlantic world.” —James Delbourgo, Rutgers University |
COULD | English meaning - Cambridge Dictionary
COULD definition: 1. past simple of "can", used to talk about what someone or something was able or allowed to do…. Learn more.
COULD Definition & Meaning - Merriam-Webster
The meaning of COULD is —used in auxiliary function in the past, in the past conditional, and as an alternative to can suggesting less force or certainty or as a polite form in the present. How …
Can vs. Could: How to Use Them Correctly - Grammarly
Mar 23, 2023 · When you’re talking about the possibility of something happening in the future, use can if something is very likely to happen. Could, on the other hand, should be used for things …
'can' and 'could' - LearnEnglish - British Council
We use could to show that something is possible, but not certain: They could come by car. (= Maybe they will come by car.) They could be at home. (= Maybe they are at home.) We use …
could - Oxford Learner's Dictionaries
Definition of could modal verb in Oxford Advanced Learner's Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more.
Could vs. Would – What’s the Difference? - Writing Explained
Could and would are related, but they mean different things. Could expresses possibility, while would expresses certainty and intent. A good way to remember the differences between these …
Can vs. Could: How to Use Them Correctly - Two Minute English
Mar 28, 2024 · Can is used to talk about something that is possible now, or to ask for permission in a casual way. For example, “I can swim” shows ability, while “Can I leave early?” asks for …
Could | ENGLISH PAGE
"Could" is a modal verb used to express possibility or past ability as well as to make suggestions and requests. "Could" is also commonly used in conditional sentences as the conditional form …
"Can" vs. "Could" – What's The Difference? - Thesaurus.com
Aug 26, 2022 · In this article, we’ll explain the differences between can and could, cover when and how both words should be used, and provide examples that show how they’re typically used in …
50 Could Sentence Examples For Better English
These could sentence examples are handy for expressing a wide range of ideas, from polite requests to past abilities and future possibilities. It allows you to add variety and nuance to …
COULD | English meaning - Cambridge Dictionary
COULD definition: 1. past simple of "can", used to talk about what someone or something was able or allowed to …
COULD Definition & Meaning - Merriam-Webster
The meaning of COULD is —used in auxiliary function in the past, in the past conditional, and as an alternative to can suggesting less force or …
Can vs. Could: How to Use Them Correctly - Grammarly
Mar 23, 2023 · When you’re talking about the possibility of something happening in the future, use can if something is very likely to happen. …
'can' and 'could' - LearnEnglish - British Council
We use could to show that something is possible, but not certain: They could come by car. (= Maybe they will come by car.) They could be at home. (= …
could - Oxford Learner's Dictionaries
Definition of could modal verb in Oxford Advanced Learner's Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage …
