Advertisement
celiac disease physiology: Handbook of Nutrition, Diet, and Epigenetics Vinood B. Patel, Victor R. Preedy, 2019-02-27 This multivolume reference work addresses the fact that the well being of humankind is predicated not only on individuals receiving adequate nutrition but also on their genetic makeup. The work includes more than 100 chapters organized in the following major sections: Introduction and Overview; Epigenetics of Organs and Diseases in Relation to Diet and Nutrition; Detailed Processes in Epigenetics of Diet and Nutrition; Modulating Epigenetics with Diet and Nutrition; and Practical Techniques. While it is well known that genes may encode proteins responsible for structural and dynamic components, there is an increasing body of evidence to suggest that nutrition itself may alter the way in which genes are expressed via the process of epigenetics. This is where chemically imposed alteration in the DNA sequence occurs or where the functional expression of DNA is modulated. This may include changes in DNA methylation, non-coding RNA, chromatin, histone acetylation or methylation, and genomic imprinting. Knowledge regarding the number of dietary components that impact on epigenetic processes is increasing almost daily. Marshalling all the information on the complex relationships between diet, nutrition, and epigenetic processes is somewhat difficult due to the wide myriad of material. It is for this reason that the present work has been compiled. |
celiac disease physiology: Understanding Celiac Disease Naheed Ali, 2014-10-16 As the market for gluten free foods continues to grow and change, many people are turning to a gluten free lifestyle for a number of reasons. Some people, however, are diagnosed with celiac disease, which is more than just a gluten sensitivity. For people with celiac disease, eating is often uncomfortable and sometimes painful; children with the disease often experience difficulties gaining weight. Understanding Celiac Disease explores the underlying causes, explains the biology, details the methods for diagnosis, and describes the symptoms and potential treatments. In easy to understand language, Dr. Naheed Ali helps demystify the subject for those who suffer, those who suspect they might suffer, and those who help care for those diagnosed with celiac disease. |
celiac disease physiology: Immunophysiology of the Gut W. Allan Walker, Paul R. Harmatz, Barry K. Wershil, 1993 This volume represents Dr. Walker's efforts to integrate intestinal physiology and the mucosal immune system by providing the first comprehensive and systematic survey of information on the immunophysiology of the gut. |
celiac disease physiology: Geriatric Gastroenterology C. S. Pitchumoni, T. Dharmarajan, 2012-07-26 As aging trends in the United States and Europe in particular are strongly suggestive of increasingly older society, it would be prudent for health care providers to better prepare for such changes. By including physiology, disease, nutrition, pharmacology, pathology, radiology and other relevant associated topics, Geriatric Gastroenterology fills the void in the literature for a volume devoted specifically to gastrointestinal illness in the elderly. This unique volume includes provision of training for current and future generations of physicians to deal with the health problems of older adults. It will also serve as a comprehensive guide to practicing physicians for ease of reference. Relevant to the geriatric age group, the volume covers epidemiology, physiology of aging, gastrointestinal physiology, pharmacology, radiology, pathology, motility disorders, luminal disorders, hepato-biliary disease, systemic manifestations, neoplastic disorders, gastrointestinal bleeding, cancer and medication related interactions and adverse events, all extremely common in older adults; these are often hard to evaluate and judge, especially considering the complex aging physiology. All have become important components of modern medicine. Special emphasis is be given to nutrition and related disorders. Capsule endoscopy and its utility in the geriatric population is also covered. Presented in simple, easy to read style, the volume includes numerous tables, figures and key points enabling ease of understanding. Chapters on imaging and pathology are profusely illustrated. All chapters are written by specialists and include up to date scientific information. Geriatric Gastroenterology is of great utility to residents in internal medicine, fellows in gastroenterology and geriatric medicine as well as gastroenterologists, geriatricians and practicing physicians including primary care physicians caring for older adults. |
celiac disease physiology: Coeliac Disease and Gluten-Related Disorders Annalisa Schiepatti, David S. Sanders, 2021-10-12 Coeliac Disease and Gluten-Related Disorders provides an updated and comprehensive overview on the crucial aspects and clinical management of gluten-related disorders. It provides an overview of the scientific background, mechanisms involved, and emphasizes the translational effect of research on clinical practice. Highlighted throughout are insights into future research areas likely to have a crucial impact in the clinical management of these common conditions. The book is perfect for researchers and gastroenterologists involved in Coeliac Disease and other gluten-related disorders. - Presents both research and clinically based perspectives on the most relevant issues of gluten-related disorders - Provides a wide-ranging discussion and the most updated opinions by international experts in the field of coeliac disease and gluten-related disorders - Translates the latest research insights into practical suggestions for specialists |
celiac disease physiology: Diarrhea Stefano Guandalini, Haleh Vaziri, 2010-10-17 This volume provides in a conveniently accessible package a comprehensive collection of accurate and timely information on the management of patients with diarrhea, both in pediatric age and in the adult. As medical knowledge has recently expanded in this area, this volume is full of new practical, clinically useful material for the busy clinician. Illustrations are emphasized to permit rapid acquisition of practical information that is not readily available in the major texts. Each chapter is concise, concentrating on clinical pearls, and new advances in diagnostic and therapeutic technology. Each chapter discusses the relative costs of diagnostic and therapeutic options to permit financial considerations to be taken into account in the decision making process. Additional unique features include, summaries of key points, recommendations, and indications for requesting GI subspecialty consultation. Providing a comprehensive but practical overview of the issues surrounding the diarrheal diseases, this volume will prove of great value and utility to gastroenterologists, surgeons, internists, primary care physicians. |
celiac disease physiology: Fast Facts: Celiac Disease Geoffrey Holmes, Carlo Catassi, Alessio Fasano, 2009-08-01 Remarkable progress has been made in our knowledge of celiac disease, yet the diagnosis is often overlooked. The practical challenge for healthcare professionals is to identify the disease and offer patients a gluten-free diet that will restore most to full health and help to prevent further complications. This comprehensively revised second edition of 'Fast Facts: Celiac Disease', written by three international experts, considers: • Celiac disease in all its forms - typical, atypical, silent, potential and latent • Gluten sensitivity, genetic risk and predisposing physiological abnormalities • The variable presentation of disease in both adults and children • Associated immune disorders • The puzzle of diagnosis, solved by clinical, serological, histological and genetic investigation • Troublesome, and sometimes life-threatening, non-malignant complications • The close links between celiac disease and dermatitis herpetiformis • The risk of malignancy, its treatment and prognosis • Management with a gluten-free diet, and the emotional and social implications of the diet • Potential new therapies Highly readable with informative illustrations, 'Fast Facts: Celiac Disease' provides an up-to-date account of this common yet easily missed condition. It is an excellent clinical resource for the primary care team, gastroenterologists in training and anyone who wants to know more about this challenging disease. Contents: • Definition • Epidemiology • Pathophysiology • Clinical manifestations • Diagnosis • Non-malignant complications • Dermatitis herpetiformis • Malignant complications • Management • Future trends • Useful resources |
celiac disease physiology: What Nurses Know...Gluten-Free Lifestyle Sylvia A. Llewelyn Bower, RN, 2011-04-18 User-friendly, evidence-based advice for living a healthy gluten-free lifestyle. If you or a loved one has been diagnosed with celiac disease or has a sensitivity or allergy to gluten, What Nurses Know: Gluten-Free Lifestyle provides the clear, science-backed information necessary to live and eat safely and well. As a registered nurse living with celiac disease, Sylvia Llewelyn Bower understands how challenging it can be to know what to eat and what to avoid, how to set up a gluten-free kitchen, what to watch for in medications, and how to safely dine out and travel. Here, she cuts through the confusion and offers clear, practical advice and tips for dealing with the every day issues and challenges of living gluten free. Youíll find: Quick-reference lists of gluten-free foods and those that contain gluten What you need to know about reading labels A one-week healing meal plan of simple, delicious, and nutritious gluten-free dishes to help you get started Ways to help a child live gluten free How to get the nutrients and vitamins you need and prevent weight gain from too many gluten-free packaged foods Advice to help you stay gluten free while traveling and eating out What Nurses Know: Gluten-Free Lifestyle takes the guesswork out of living gluten free. About the Series Nurses constantly straddle the line between the world of medicine and the patientís experience. This series offers down-to-earth, evidence-based advice from expert nurses who offer straightforward and practical guidance for dealing with all kinds of medical conditions. |
celiac disease physiology: Advanced Nutrition and Dietetics in Gastroenterology Miranda Lomer, 2014-08-25 Advanced Nutrition and Dietetics in Gastroenterology provides informative and broad-ranging coverage of the relation between nutrition and diet and the gastrointestinal tract. It explores dietary factors involved in causation of a variety of gastrointestinal disorders, as well as the effects on diet and the treatments available. It also provides an overview of anatomy and physiology, measurement and assessment of function, and dietary components relevant to gastrointestinal health. ABOUT THE SERIES Dietary recommendations need to be based on solid evidence, but where can you find this information? The British Dietetic Association and the publishers of the Manual of Dietetic Practice present an essential and authoritative reference series on the evidence base relating to advanced aspects of nutrition and diet in selected clinical specialties. Each book provides a comprehensive and critical review of key literature in its subject. Each covers established areas of understanding, current controversies and areas of future development and investigation, and is oriented around six key themes: •Disease processes, including metabolism, physiology, and genetics •Disease consequences, including morbidity, mortality, nutritional epidemiology and patient perspectives •Nutritional consequences of diseases •Nutritional assessment, drawing on anthropometric, biochemical, clinical, dietary, economic and social approaches •Clinical investigation and management •Nutritional and dietary management •Trustworthy, international in scope, and accessible, Advanced Nutrition and Dietetics is a vital resource for a range of practitioners, researchers and educators in nutrition and dietetics, including dietitians, nutritionists, doctors and specialist nurses. |
celiac disease physiology: Immunopathology of Celiac Disease Lorenzo Galluzzi, Ainara Castellanos, 2021-03-02 Immunopathology of Celiac Disease, Volume 359 presents the latest release in this ongoing series on novel and widely studied aspects of celiac disease pathogenesis. Topics covered in this new volume include Omics of Celiac Disease, Implication of HLA genes in Celiac Disease, Macrophages & Dendritic Cells in Celiac Disease, Tight junction disruption in the development of celiac disease, Implication of epithelial cell dysfunction in CeD, Involvement of p31-p43 gluten peptide in the celiac disease related immune/inflammatory response, The biology of refractory celiac disease, Involvement of lncRNAs in Celiac disease pathogenesis, and more. Provides up-to-date and extensive reviews of different aspects of celiac disease pathogenesis Includes original figures that help readers understand the complex pathways involved in the disease Covers research on different aspects of the disease which involves the introduction of a wide range of technologies |
celiac disease physiology: The Microbiota in Gastrointestinal Pathophysiology Martin H. Floch, Yehuda Ringel, W. Allen Walker, 2016-11-16 The Microbiota in Gastrointestinal Pathophysiology: Implications for Human Health, Prebiotics, Probiotics and Dysbiosis is a one-stop reference on the state-of-the-art research on gut microbial ecology in relation to human disease. This important resource starts with an overview of the normal microbiota of the gastrointestinal tract, including the esophagus, stomach, Ileum, and colon. The book then identifies what a healthy vs. unhealthy microbial community looks like, including methods of identification. Also included is insight into which features and contributions the microbiota make that are essential and useful to host physiology, as is information on how to promote appropriate mutualisms and prevent undesirable dysbioses. Through the power of synthesizing what is known by experienced researchers in the field, current gaps are closed, raising understanding of the role of the microbiome and allowing for further research. - Explains how to modify the gut microbiota and how the current strategies used to do this produce their effects - Explores the gut microbiota as a therapeutic target - Provides the synthesis of existing data from both mainstream and non-mainstream sources through experienced researchers in the field - Serves as a 'one-stop' shop for a topic that's currently spread across a number of various journals |
celiac disease physiology: Mesenteric Vascular Disease Gustavo S. Oderich, 2014-11-20 This book represents the first comprehensive textbook devoted to the standard of care, current guidelines and innovations in the field of mesenteric vascular disease. The book reviews imaging modalities, diagnostic work up, physiologic tests, traditional open surgical techniques and novel endovascular approaches. Technical aspects of both open surgical and endovascular techniques are provided by experts in the field, with illustrations and photographs of key steps for each type of procedure. Results of epidemiologic studies and national databases are summarized, as well as large institutional experiences. An evidence-based approach is used for recommendations regarding best therapies. Diagnostic approaches including imaging and novel physiologic tests, including gastric tonometry and oxygen light spectroscopy are covered. Mesenteric Vascular Disease: Current Therapy will serve as a very useful resource for clinicians, surgeons, interventionalists, gastroenterologists and researchers dealing with and interested in mesenteric vascular diseases. |
celiac disease physiology: Diabetes Mellitus in Children Mark A. Sperling, 2005 |
celiac disease physiology: Pearls and Tricks in Pediatric Surgery Martin Lacher, Shawn D. St. Peter, Augusto Zani, 2020-10-29 Providing core information on pediatric surgery, this book serves as a supplement to standard pediatric surgical textbooks. It offers pearls of wisdom that will help those who participate in pediatric surgical care, as well as to provide state-of-the-art insights based on physiological principles, literature reviews, and clinical experience. This book is an ideal tool to help readers prepare for questions they will be asked on ward rounds, in the OR, or in oral exams. The depth of exploration is intended for medical students, residents in pediatrics and pediatric surgery, pediatric surgical trainees, pediatric nurse practitioners, primary care pediatricians, and family practitioners. |
celiac disease physiology: Celiac Disease (Updated 4th Edition) Peter H. R. Green, Rory Jones, 2020-12 From Dr. Peter H. R. Green, internationally renowned expert on celiac disease and director of the Celiac Disease Center at Columbia University, and medical author Rory Jones, an updated fourth edition of the definitive book on celiac disease, one of the most underdiagnosed autoimmune diseases in the U.S. Celiac Disease: A Hidden Epidemic is an indispensable guidebook for anyone with celiac disease as well as those on a gluten-free diet with gluten intolerance or sensitivity. Since the last edition in 2016, scientific advances have changed what we know about the disease, how it is diagnosed and treated, and the long-term effect of a GF diet on the brain and body. Celiac disease is a hereditary autoimmune condition that damages the lining of the small intestine so that it cannot properly absorb food. Without essential nutrients, the entire body begins to suffer. The disease is triggered by gluten, a protein found in wheat, rye, and barley. The only cure for the disease is a life-long gluten-free diet. The disease affects nearly 1 in every 100 people in the United States but as many as 50 percent of patients remain undiagnosed and untreated. Although the primary target of injury is the small intestine, CD can and often does affect the entire body. Complications from the disease can include infertility, liver disease, osteoporosis, anemia, and other autoimmune diseases (such as Type 1 diabetes and Thyroid disease), neurological conditions, and even cancer. This revised and updated fourth edition contains the most current information on CD, gluten intolerance, and gluten sensitivity. The important updates cover everything from new testing devices to advances in therapies that may help prevent gluten from entering and/or harming the intestines, to new research on the long-term effect of the gluten-free diet on our minds and bodies. --Library Journal |
celiac disease physiology: Celiac Disease (Updated 4th Edition) Peter H.R. Green, M.D., Rory Jones, 2020-12-01 From Dr. Peter H. R. Green, internationally renowned expert on celiac disease and director of the Celiac Disease Center at Columbia University, and medical author Rory Jones, an updated fourth edition of the definitive book on celiac disease, one of the most underdiagnosed autoimmune diseases in the U.S. Celiac Disease: A Hidden Epidemic is an indispensable guidebook for anyone with celiac disease as well as for those with gluten intolerance or food sensitivities on a gluten-free diet. Since the last edition in 2016, scientific advances have changed what we know about the disease, how it is diagnosed and treated, and the long-term effect of a gluten-free diet on the brain and body. Celiac disease is a hereditary autoimmune condition that damages the lining of the small intestine so that it cannot properly absorb food. Without essential nutrients, the entire body begins to suffer. The disease is triggered by gluten, a protein found in wheat, rye, and barley. The only “cure” for the disease is a life-long gluten-free diet. The disease affects nearly 1 in every 100 people in the United States—50 percent of whom remain undiagnosed and untreated. Although the primary target of injury is the small intestine, CD can and often does affect the entire body. Complications from the disease can include infertility, liver disease, osteoporosis, anemia, and other autoimmune diseases (such as Type 1 diabetes and Thyroid disease), neurological conditions, and even cancer. This updated fourth edition includes the latest information on CD, gluten intolerance, and gluten sensitivity. The important updates cover everything from new testing devices to advances in therapies that may help prevent gluten from entering and/or harming the intestines, to new research on the long-term effect of the gluten-free diet on our minds and bodies. And more! |
celiac disease physiology: Anatomy and Physiology J. Gordon Betts, Peter DeSaix, Jody E. Johnson, Oksana Korol, Dean H. Kruse, Brandon Poe, James A. Wise, Mark Womble, Kelly A. Young, 2013-04-25 |
celiac disease physiology: Frontiers in Celiac Disease Alessio Fasano, Riccardo Troncone, D. Branski, 2008-01-01 Few other fields in human biology have experienced such a tremendous progress as celiac disease has during the past few years. The contributors to 'Frontiers in Celiac Disease' are world-renowned opinion leaders who made these advances possible. Their expertise has been assembled here to provide a comprehensive overview of the current knowledge of the epidemiology, pathogenesis, clinical presentations, diagnosis and treatment of celiac disease. In addition, the stage is set for innovative strategies for preventive interventions and treatment alternatives to a gluten-free diet. A valuable reference for basic and translational scientists, this book also serves as a practical resource to healthcare professionals, including general practitioners, subspecialists, dieticians, nutritionists, and nurses and nurse practitioners. Students from different disciplines will find this book a helpful guide to expand and deepen their knowledge of celiac disease. |
celiac disease physiology: Pathophysiology of Disease: An Introduction to Clinical Medicine 7/E (ENHANCED EBOOK) Gary D. Hammer, Stephen J. McPhee, 2014-03-22 A full-color, case-based review of the essentials of pathophysiology--covering all major organs and systems The goal of this trusted text is to introduce you to clinical medicine by reviewing the pathophysiologic basis of 120 diseases (and associated signs and symptoms) commonly encountered in medical practice. The authors, all experts in their respective fields, have provided a concise review of relevant normal structure and function of each body system, followed by a description of the pathophysiologic mechanisms that underlie several common diseases related to that system. Each chapter of Pathophysiology of Disease concludes with a collection of case studies and questions designed to test your understanding of the pathophysiology of each clinical entity discussed. These case studies allow you to apply your knowledge to specific clinical situations. Detailed answers to each case study question are provided at the end of the book. This unique interweaving of physiological and pathological concepts will put you on the path toward thinking about signs and symptoms in terms of their pathophysiologic basis, giving you an understanding of the why behind illness and treatment. Features 120 case studies (9 new) provide an opportunity for you to test your understanding of the pathophysiology of each clinical entity discussed Checkpoint questions provide review and appear in every chapter Updates and revisions throughout this new edition reflect the latest research and developments Numerous tables and diagrams encapsulate important information Updated references for each chapter topic Pathophysiology of Disease is a true must-have resource for medical students preparing for the USMLE Step 1 exam, as well as students engaged in their clerkship studies. House officers, nurses, nurse practitioners, physicians’ assistants, and allied health practitioners will find its concise presentation and broad scope a great help in facilitating their understanding of common disease entities. |
celiac disease physiology: The Gluten-Free Edge: A Nutrition and Training Guide for Peak Athletic Performance and an Active Gluten-Free Life (No Gluten, No Problem) Peter Bronski, Melissa McLean Jory, 2012-07-17 Gain an edge in sports and life by going gluten-free Since the advent of sport, athletes have worked to gain an edge on their competition—to look, feel, and perform their best—through both training and nutrition. Today, science is increasingly showing the negative impact that gluten, a protein in wheat, barley, and rye, can have on health. For the estimated 30 million Americans with forms of gluten intolerance, such as celiac disease, this all-too-common protein can cause gastrointestinal trouble, inflammation, muscle fatigue, and mental fog that hinder an active lifestyle and negatively impact athletic performance. The solution: a whole-foods, nutrient-dense gluten-free diet. Others who voluntarily eat gluten-free can also discover an edge they never knew was missing: faster recovery, reduced inflammation, improved digestion, and increased athletic performance. The Gluten-Free Edge is the first comprehensive resource that includes: • What gluten is and how it negatively impacts health and athletic performance • The myriad benefits of adopting a gluten-free nutrition plan • What to eat during training, competition, and recovery • How to deal with group meals, eating on the road, and getting “glutened” • Insights from prominent athletes already living the gluten-free edge • And 50 simple, high-octane recipes to fuel your performance Whether you’ve been diagnosed with gluten intolerance or simply want to get ahead of the competition, this book is for you. Your own gluten-free edge is waiting. |
celiac disease physiology: Free Fatty Acid Receptors Graeme Milligan, Ikuo Kimura, 2017-02-08 This book highlights the important role free fatty acids (FFA) play as potential drug targets. While FFA have long been considered byproducts of cell metabolism, they are now recognized as ligands that regulate cell and tissue function via G-protein-coupled receptors. At least three receptors have been identified for which FFA appear to be the endogenous ligands. |
celiac disease physiology: The Gluten Lie Alan Levinovitz, 2015-04-21 An incendiary work of science journalism debunking the myths that dominate the American diet and showing readers how to stop feeling guilty and start loving their food again—sure to ignite controversy over our obsession with what it means to eat right. FREE YOURSELF FROM ANXIETY ABOUT WHAT YOU EAT Gluten. Salt. Sugar. Fat. These are the villains of the American diet—or so a host of doctors and nutritionists would have you believe. But the science is far from settled and we are racing to eliminate wheat and corn syrup from our diets because we’ve been lied to. The truth is that almost all of us can put the buns back on our burgers and be just fine. Remember when butter was the enemy? Now it’s good for you. You may have lived through times when the Atkins Diet was good, then bad, then good again; you may have wondered why all your friends cut down on salt or went Paleo; and you might even be thinking about cutting out wheat products from your own diet. For readers suffering from dietary whiplash, The Gluten Lie is the answer. Scientists and physicians know shockingly little about proper nutrition that they didn’t know a thousand years ago, even though Americans spend billions of dollars and countless hours obsessing over “eating right.” In this groundbreaking work, Alan Levinovitz takes on bestselling physicians and dietitians, exposing the myths behind how we come to believe which foods are good and which are bad—and pointing the way to a truly healthful life, free from anxiety about what we eat. |
celiac disease physiology: Passing the Certified Bariatric Nurses Exam Andrew Loveitt, Margaret M. Martin, Marc A. Neff, 2017-01-03 The Certified Bariatric Nurse (CBN) designation was created by the American Society for Metabolic and Bariatric Surgery to fill the rapidly growing need for nurses specialized in the care of patients undergoing weight loss surgery. This book approaches this subject area to assist nurses interested in passing the CBN exam. It can also be used as a general resource for those interested in a comprehensive but concise review of the rapidly growing field of Bariatric Surgery. This would include medical students, residents, dietitians, and other allied health professionals. Dr. Marc Neff is a recognized expert in the field of Bariatric Surgery. In his current position, his hospital is fortunate to have several CBNs caring for the Bariatric patients. With his guidance, along with several nurses who successfully completed the CBN designation, the authors have created a concise, quick hit review of the material required to successfully pass the exam. The format is short chapters followed by 5-10 review questions with in-depth explanations. Where appropriate, graphics are provided to highlight the essential anatomy and surgical procedures. Questions are in multiple choice format to simulate the actual CBN exam. |
celiac disease physiology: Pathophysiology of Blood Archie A. MacKinney, 1984 |
celiac disease physiology: Autism Spectrum Disorders Andreas M. Grabrucker, 2021 Autism spectrum disorders are developmental disorders. Individuals with autism spectrum disorders develop differently. These differences are usually present in social interaction, communication, and sensory processing, and become visible through a wide variety of behavioral responses that differ from individuals without autism spectrum disorders. Despite significant research efforts, the exact causes of autism spectrum disorders remain poorly understood; however, researchers have gained extensive insights into possible pathomechanisms, even at the molecular level of cells. Many diagnostic criteria have been developed, adapted, and improved. The eight chapters in this book highlight the current state-of-the-art in many areas of autism spectrum disorders. Chapter 1 provides an overview of the epidemiology of autism spectrum disorders and the current knowledge of the underlying pathogenic mechanisms. Chapter 2 summarizes the diagnostic criteria and procedures and highlights present and upcoming therapeutic strategies. Chapter 3 reviews the adverse events and trauma in people with autism spectrum disorders. Chapters 4 and 5 focus on atypical sensory processing, and Chapter 6 discusses the genetic overlap of autism spectrum disorders with other neuropsychiatric disorders such as attention deficit hyperactivity disorder (ADHD), depression, and schizophrenia. Chapter 7 focuses on the contribution of abnormalities in mitochondria, and chapter 8 discusses gut-brain interactions and a potential role for microbiota in autism spectrum disorders. This book is aimed primarily at clinicians and scientists, but many areas will also be of interest to the layperson. |
celiac disease physiology: Food Protein Induced Enterocolitis (FPIES) Terri Faye Brown-Whitehorn, Antonella Cianferoni, 2019-08-20 This unique book is a first-of-its-kind resource, comprehensively guiding readers through the epidemiology, pathophysiology, recent diagnostic criteria, and management options for patients with Food Protein-Induced Enterocolitis Syndrome (FPIES). Food-Protein Induced Enterocolitis Syndrome: Diagnosis and Management opens with a historical perspective of this condition, before moving into discussions of epidemiology and pathophysiology. FPIES can be difficult to diagnose as the symptoms overlap with multiple other conditions, and so clear differential diagnosis will be reviewed for both chronic FPIES, as well as acute FPIES. Later chapters are case-based, providing detailed multiple perspectives on the diagnosis and management of FPIES in patients with varying complicating factors and severity. Later chapters will tackle issues of quality of life in patient care, nutritional management for patients, and discussing working with parents and families to improve communication and at-home care. Parents, families and caregivers will also find chapters useful and relatable. A final chapter will look to the future of FPIES, addressing new research, guidelines, and implications for clinicians working with pediatric patients with FPIES, and for their families. Concise and practical, this book will be an ideal reference for allergists, pediatricians, family practice clinicians, gastroenterologists, nutritionists, and all other health care providers who encounter FPIES, and assist them in providing up-to-date, quality care for pediatric patients affected by this condition. |
celiac disease physiology: Challenges and Potential Solutions in Gluten Free Product Development Navneet Singh Deora, Aastha Deswal, Madhuresh Dwivedi, 2021-12-04 This work provides researchers with a thorough overview of all aspects related to the development of gluten-free food products. In summarizing and offering critical reviews of published works and focusing on current advances and technologies in gluten free product development, this book covers all of the important subjects related to this increasingly important aspect of the food industry. Important case studies in gluten-free breadmaking and alternative proteins are presented, making this a rich and singular source for food manufacturers and scientists seeking practical knowledge on the challenges and solutions involved in the development of gluten-free foods. Challenges and Potential Solutions in Gluten Free Product Development covers the latest advances and strategies for gluten-free diets including the important nutritional factors involved. Traditional and alternative approaches for the development of gluten-free dough, including starch applications and microbial fermentations, are extensively covered. Alternative proteins including those from vegetables, cereals, legumes and eggs are presented. Novel approaches for gluten-free breadmaking such as aeration strategies, prebiotics, hydrocolloids and nutritional enhancements are also covered in depth. With further chapters dedicated to regulatory aspects, gluten detection methods and the global market, this book presents full and up-to-date coverage of the development and manufacture of gluten-free products. |
celiac disease physiology: Liver Disease in Children Frederick J. Suchy, Ronald J. Sokol, William F. Balistreri, 2007-05-07 Completely revised new edition of the premier reference on pediatric liver disease. Liver Disease in Children, 3rd Edition provides authoritative coverage of every aspect of liver disease affecting infants, children, and adolescents. The book offers an integrated approach to the science and clinical practice of pediatric hepatology and charts the substantial progress in understanding and treating these diseases. Chapters are written by international experts and address the unique pathophysiology, manifestations, and management of these disorders in the pediatric population. The third edition has been thoroughly updated and features new contributions on liver development, cholestatic and autoimmune disorders, fatty liver disease, and inborn errors of metabolism. With the continued evolution of pediatric hepatology as a discipline, this text remains an essential reference for all physicians involved in the care of children with liver disease. |
celiac disease physiology: Sleisenger and Fordtran's Gastrointestinal and Liver Disease E-Book Mark Feldman, Lawrence S. Friedman, Lawrence J. Brandt, 2015-01-01 Now in its 10th edition, Sleisenger and Fordtran?s Gastrointestinal and Liver Disease remains your indispensable source for definitive, state-of-the-art answers on every aspect of gastroenterology and hepatology. Overcome your most complex clinical challenges and make optimal use of the newest techniques, technologies, and treatments?with superb guidance from hundreds of world-renowned authorities. Meticulous updates throughout include the latest approaches and improvements in gastrointestinal and liver disease diagnosis and therapy as well as hundreds of images and 35 new procedural videos. ..one of the most valuable clinical resources in the dynamic field of gastroenterology and hepatology. Reviewed by Brindusa Diaconu on behalf of the Journal of Gastrointestinal and Liver Diseases, July 2015 ..an engaging, educational yet clinically orientated textbook which is relevant to modern clinical practice. Reviewed by Dr Harry Brown on behalf of glycosmedia.com, April 2015 I can personally attest to the remarkable advances that have been made, as I was author of the chapter on eosinophilic gastroenteritis in the second edition of the textbook, and reading the same chapter in the tenth edition underscores the important advances that have been made in our understanding of the molecular basis as well as the pathophysiology of this and related disorders. Foreword by Norton J. Greenberger, MD Boston, Massachusetts, June 2015 Consult this title on your favorite e-reader. Get the essential gastroenterology information you need from one authoritative source with an outstanding global reputation for excellence. Zero in on the key information you need to know with a consistent, full-color chapter design. Stay up to date with emerging and challenging topics: enteric microbiota and probiotics; fecal microbiota transplantation; Clostridium difficile colitis; and factitious gastrointestinal diseases. Incorporate the latest findings and improvements in care for liver disease patients—from diagnosis and treatment through post-treatment strategies and management of complications. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices. |
celiac disease physiology: Ferri's Differential Diagnosis Fred F. Ferri, MD, FACP, 2010-08-26 Ferri's Differential Diagnosis is a quick reference to the differential diagnosis, etiology, and classification of clinical disorders, signs, and symptoms. Dr. Fred F. Ferri-the respected best-selling author-presents over 1000 signs, symptoms, and clinical disorders. Comprehensive yet small enough to fit in your pocket, this portable guide is a rapid resource for everything you see in daily practice-from abdominal distension to Zenker's Diverticulum. Quickly locate the information you need with an organization that presents differential diagnosis by sign and symptom as well as disorder. Easily identify the likeliest diagnosis through diagnostic possibilities listed in order of incidence. Tap into the authoritative guidance of Dr. Fred Ferri, the respected expert responsible for best-selling titles such as Ferri's Clinical Advisor, Ferri's Fast Facts, and Practical Guide to the Care of the Medical Patient. Apply the differential diagnosis of over 100 new signs, symptoms, and clinical disorders. |
celiac disease physiology: Laposata's Laboratory Medicine Diagnosis of Disease in Clinical Laboratory Third Edition Michael Laposata, 2018-12-25 Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The acclaimed full-color guide to selecting the correct laboratory test and interpreting the results –- covering ALL of clinical pathology Laboratory Medicine is the most comprehensive, user-friendly, and well-illustrated guide available for learning how to order the correct laboratory test and understand the clinical significance of the results. The book features an easy-to-follow, consistent presentation for each disease discussed. Chapters begin with a brief description of the disorder followed by a discussion that includes tables detailing the laboratory evaluation of specific disorders, diagnosis, baseline tests to exclude diagnostic possibilities, and clinical indications that warrant further screening and special testing. With new, increasingly expensive and complicated tests appearing almost daily, Laboratory Medicine, Third Edition is required reading for medical students, clinical laboratory scientists, and healthcare professionals who want to keep abreast of the latest testing procedures and maximize accuracy and patient safety. Features: •48 clinical laboratory methods presented in easy-to-understand illustrations that include information on the expense and complexity of the assays •More than 200 tables and full-color algorithms that encapsulate important information and facilitate understanding •Full-color blood-smear micrographs that demonstrate common abnormal morphologies of red blood cells •Valuable learning aids in each chapter, including learning objectives, chapter outlines, and a general introduction -- and new to this edition: chapter-ending self-assessment Q&A•Logical systems-based organization that complements most textbooks •Extensive table of Clinical Laboratory Reference Values that show the conversions between U.S. and SI units for each value |
celiac disease physiology: Celiac Disease and Non-Celiac Gluten Sensitivity Luis Rodrigo, Amado Salvador Peña, 2014-11-07 Celiac disease is a systemic autoimmune process and appears in genetically predisposed individuals, with a well-known cause, consisting in a permanent intolerance to gluten, a protein contained in the flour of wheat, rye, barley and oats. Worldwide celiac disease affects to 1% of the Caucasian and there is recent evidence that the disease is increasing in USA and Finland among other regions in the world. It is considered to be the most prevalent disease with a genetic predisposition. The clinical forms of presentation are varied. The classical form consisting of diarrhea, anemia and failure to thrive is still common in children, but in the adult patients the symptoms resemble the irritable bowel syndrome. Mono-symptomatic forms with extra-intestinal manifestations are frequent. Hematological, cutaneous, articular, hepatic, bone and neurological manifestations are often described. This protean presentation and the lack of awareness explain the delay in diagnosis and suggest that screening in high-risk groups is indicated. The publication of this book written mainly by Spanish and Latin-American clinicians, researchers, and teachers, demonstrates the wide interest and the involvement of different disciplines that are necessary to understand celiac disease and gluten-related pathologies, such as non-celiac gluten-sensitivity. This has a great impact in the general public and in the industry. However, the knowledge of non-celiac gluten-related pathologies remains scarce but presently in the process of being properly defined. This book also highlights the importance of recognizing non-celiac gluten-sensitivity and briefly discusses a new definition. It also provides some perspectives to take into account when studying celiac disease in China and Central America. It describes new observations in Mexico, El Salvador and Costa Rica. The psychosocial impact as studied and reported by Argentinean investigators also adds to the value of this book. Written with a multidisciplinary team, we think that this book could be of interest to a great variety of medical specialists. Due to the systemic nature and variable presentation of celiac disease it certainly is of interest to pediatricians, gastroenterologists, hepatologists, specialists in internal medicine, general practitioners as well as hematologists, immunologists, geneticists, pathologists, rheumatologists, dermatologists, neurologists, gynecologists, neurologists, psychiatrists, psychologists, orthopedic surgeons, specialists in rehabilitation medicine, endocrinologists. Being gluten the cause of these disorders, the food industry, dietitians and nutritionists will benefit from the valuable information presented in this book. |
celiac disease physiology: Wintrobe's Clinical Hematology John P. Greer, Daniel A. Arber, Bertil Glader, Alan F. List, Robert T. Means, Frixos Paraskevas, George M. Rodgers, 2013-08-29 With the 13th edition, Wintrobe’s Clinical Hematology once again bridges the gap between the clinical practice of hematology and the basic foundations of science. Broken down into eight parts, this book provides readers with a comprehensive overview of: Laboratory Hematology, The Normal Hematologic System, Transfusion Medicine, Disorders of Red Cells, Hemostasis and Coagulation; Benign Disorders of Leukocytes, The Spleen and/or Immunoglobulins; Hematologic Malignancies, and Transplantation. Within these sections, there is a heavy focus on the morphological exam of the peripheral blood smear, bone marrow, lymph nodes, and other tissues. With the knowledge about gene therapy and immunotherapy expanding, new, up-to-date information about the process and application of these therapies is included. Likewise, the editors have completely revised material on stem cell transplantation in regards to both malignant and benign disorders, graft versus host disease, and the importance of long-term follow-up of transplantation survivors. |
celiac disease physiology: Gluten-Free Food Science and Technology Eimear Gallagher, 2009-09-08 Coeliac disease (CD) and other allergic reactions/intolerances to gluten are on the rise, largely due to improved diagnostic procedures and changes in eating habits. The worldwide incidence of coeliac disease has been predicted to increase by a factor of ten over the next number of years, and this has resulted in a growing market for high quality gluten-free cereal products. However, the removal of gluten presents major problems for bakers. Currently, many gluten-free products on the market are of low quality and short shelf life, exhibiting poor mouthfeel and flavour. This challenge to the cereal technologist and baker alike has led to the search for alternatives to gluten in the manufacture of gluten-free bakery products. This volume provides an overview for the food industry of issues related to the increasing prevalence of coeliac disease and gluten intolerance. The properties of gluten are discussed in relation to its classification and important functional characteristics, and the nutritional value of gluten-free products is also addressed. The book examines the diversity of ingredients that can be used to replace gluten and how the ingredient combinations and subsequent rheological and manufacturing properties of a range of gluten-free products, e.g. doughs, breads, biscuits and beer may be manipulated. Recommendations are given regarding the most suitable ingredients for different gluten-free products. The book is directed at ingredient manufacturers, bakers, cereal scientists and coeliac associations and societies. It will also be of interest to academic food science departments for assisting with undergraduate studies and postgraduate research. The Author Dr Eimear Gallagher, Ashtown Food Research Centre, Teagasc - The Irish Agriculture and Food Development Authority, Dublin, Ireland Also available from Wiley-Blackwell Management of Food Allergens Edited by J. Coutts and R. Fielder ISBN 9781405167581 Bakery Manufacture and Quality - Water Control and Effects Second Edition S. Cauvain and L. Young ISBN 9781405176132 Whole Grains and Health Edited by L. Marquart et al ISBN 9780813807775 |
celiac disease physiology: Celiac Disease Peter Kruzliak, Govind Bhagat, 2012-07-19 Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten-containing grains (including wheat, rye and barley) in genetically susceptible individuals. CD can manifest itself with a previously unappreciated range of clinical presentations, including the typical malabsorption syndrome and a spectrum of symptoms potentially affecting any organ system. Since CD often presents in an atypical or even silent manner, many cases remain undiagnosed and carry the risk of long-term complications, including anemia and other hematological complications, osteoporosis, neurological complications or cancer. The high prevalence of the disease and its variety of clinical outcomes raise several interesting questions. This book covers most of the aforementioned controversial and yet unresolved topics by including the contributions of experts in CD.What the reader will surely find stimulating about this book is not only its exhaustive coverage of our current knowledge of CD, but also provocative new concepts in disease pathogenesis and treatment. |
celiac disease physiology: Anatomy & Physiology Lindsay Biga, Devon Quick, Sierra Dawson, Amy Harwell, Robin Hopkins, Joel Kaufmann, Mike LeMaster, Philip Matern, Katie Morrison-Graham, Jon Runyeon, 2019-09-26 A version of the OpenStax text |
celiac disease physiology: Physiology of the Gastrointestinal Tract Leonard R. Johnson, 1994 |
celiac disease physiology: Pathology: A Modern Case Study Howard Reisner, 2014-09-22 A unique case-based molecular approach to understanding pathology Pathology: A Modern Case Study is a concise, focused text that emphasizes the molecular and cellular biology essential to understanding the concepts of disease causation. The book includes numerous case studies designed to highlight the role of the pathologist in the team that provides patient care. Pathology: A Modern Case Study examines the role of anatomic, clinical, and molecular pathologists in dedicated chapters and in descriptions of the pathology of specific organ systems. Features Coverage of pathology focuses on modern approaches to common and important diseases Each chapter delivers the most up-to-date advances in pathology Learning aids include chapter summaries and overviews, bolded terms, and a glossary Common clinically relevant disease are highlighted Disease discussion is based on organ compartment and etiology Coverage includes: Disease and the Genome: Genetic, Developmental and Neoplastic Disease Cell Injury, Death and Aging and the Body's Response Environmental Injury Clinical Practice: Anatomic Pathology Clinical Practice: Molecular Pathology Clinical Practice: Molecular Pathology Organ-specific pathology covering all major body systems Molecular pathology Essential for undergraduate medical students and clinicians who wish to expand their knowledge pathology, Pathology: A Modern Case Study delivers valuable coverage that is directly related to a patient’s condition and the clinical practice of pathology. |
celiac disease physiology: Computational Methods for Single-Cell Data Analysis Guo-Cheng Yuan, 2019-02-14 This detailed book provides state-of-art computational approaches to further explore the exciting opportunities presented by single-cell technologies. Chapters each detail a computational toolbox aimed to overcome a specific challenge in single-cell analysis, such as data normalization, rare cell-type identification, and spatial transcriptomics analysis, all with a focus on hands-on implementation of computational methods for analyzing experimental data. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Methods for Single-Cell Data Analysis aims to cover a wide range of tasks and serves as a vital handbook for single-cell data analysis. |
celiac disease physiology: Physiology of the Ear Joseph R. Santos-Sacchi, 2001 At a level for doctoral or medical students in neurosciences, audiology, or physiology, Physiology of the Ear, 2E has brought together in a complete and concise manner a compilation of articles written by experts in their specialty and addressing clinical and basic science aspects of ear physiology. The text begins with a history of the discovery of the anatomy and physiology of the ear and works systematically from the external, middle, and inner ear to the brain. Easy to read and understand, this text can be used as a resource or as a tool for study and review. It covers topics such as sound and bone conduction mechanisms, signal processing, stimulus coding in the auditory system, blood circulation of the cochlea, and auditory brain mapping. It highlights the application of new research findings to the management problems encountered in everyday practice, and covers important aspects of nonauditory physiology such as skin migration in the ear canal. |
Celiac Disease Summary - Columbia University
Celiac disease is a systemic autoimmune disease with gastrointestinal symptoms and multiple, highly variable non-gastrointestinal symptoms (see Figure 2). It is induced by dietary gluten in …
Pathogenesis of Celiac Disease - NASPGHAN
Celiac disease is an immune-mediated enteropathy caused by a permanent sensitivity to gluten in genetically susceptible individuals. It occurs in symptomatic subjects with gastrointestinal and …
Celiac Disease and Nonceliac Gluten SensitivityA Review
IMPORTANCE The prevalence of gluten-related disorders is rising, and increasing numbers of individuals are empirically trying a gluten-free diet for a variety of signs and symptoms. This …
Celiac disease: mechanisms and emerging therapeutics - Cell …
Celiac disease (CeD) is a widespread, gluten-induced, autoimmune disorder that lacks any medicinal therapy. Towards the goal of developing non-dietary treat-ments for CeD, research …
Lessons from rodent models in celiac disease - Nature
Herein, we review how approaches in rodents have provided insight into celiac disease pathophysiology and also highlight the difficulties met to fully recapitulate the human disease.
Celiac Disease: The Evolutionary Paradox - Science and …
2. Physiology of Celiac Disease Celiac disease, also called gluten-sensitive enteropathy, is a chronic inflammatory disease of the small intestine that can develop in genetically-susceptible …
Celiac Disease: Should we care about microbes?
Jun 12, 2019 · Here, we discuss the evidence regarding the role of microbes in promoting CeD, 17 and the specific pathways triggered by microbes that could participate in CeD pathogenesis. 18 …
Celiac Disease: Common Questions and Answers - AAFP
Celiac disease is an immune-mediated, multisystem disorder that affects genetically susceptible individuals who are exposed to gluten-containing grains such as wheat, barley, and rye.
Overview and Pathogenesis of Celiac Disease
Celiac disease is characterized by small intestinal mu- cosal injury and nutrient malabsorption in geneti-cally susceptible individuals following the dietary inges-tion of “gluten.”
Measuring Change In Small Intestinal Histology In Patients …
Subjective methods to grade celiac disease histological severity include the Marsh-Oberhuber and Corazza-Villanacci systems. Quantitative histology uses villus height (Vh), crypt depth (Cd), …
WHAT IS CELIAC DISEASE? - Celiac Canada
CELIAC DISEASE? Celiac disease (CD) is a permanent intolerance to gluten, a protein found in various wheat, rye, barley and triticale. Gluten consumption damages the small intestine and …
Identification of Food-grade Subtilisins as Gluten-degrading …
Jul 28, 2016 · The disease is characterized by inflammation and flattening of the 70 duodenal and jejunal villi, with a broad spectrum of symptoms, ranging from a clinically silent disease to 71 …
Celiac Disease and Imbalance of Intestinal Flora
Celiac disease is an autoimmune pathology of a genetic nature triggered by the consumption of gluten and characterized by histological changes in the intestine of genetically arranged …
Hematologic Manifestations of Celiac Disease - IntechOpen
Celiac disease is a systemic disease, which is associated with a number of hematologic manifestations. Individuals can present with hematological abnormalities even prior to the …
NIH Consensus Statement on Celiac Disease
• How is celiac disease diagnosed? • How prevalent is celiac disease? • What are the manifestations and long-term consequences of celiac disease? • Who should be tested for …
Gut microbiome investigation in celiac disease: from methods …
role in human physiology, and its alteration (“dysbiosis”) has been linked to a variety of inflammatory gut diseases, including celiac disease (CD). CD is a chronic, immune-mediated …
Celiac disease: should we care about microbes?
Apr 10, 2019 · Here, we discuss the evidence regarding the role of microbes in promoting CeD and the specific pathways triggered by microbes that could participate in CeD pathogenesis. …
Celiac Disease: Diagnosis and Management - AAFP
Celiac disease is characterized by chronic inflammation of the small intestinal mucosa, which leads to atrophy of the small intestinal villi and subsequent malabsorption. The condition...
Despite sequence homologies to gluten, salivary proline-rich …
May 20, 2015 · CELIAC DISEASE (CD) is a T cell-mediated inflammatory enter-opathy that manifests itself in genetically predisposed individ-uals. In its etiology, both genetic and …
Identification of food-grade subtilisins as gluten-degrading …
May 5, 2016 · First published July 28, 2016; doi:10.1152/ajpgi.00185.2016.—Gluten are proline- and glutamine-rich proteins present in wheat, barley, and rye and contain the immunogenic …
Celiac Disease Summary - Columbia University
Celiac disease is a systemic autoimmune disease with gastrointestinal symptoms and multiple, highly variable non-gastrointestinal symptoms (see Figure 2). It is induced by dietary gluten in …
Pathogenesis of Celiac Disease - NASPGHAN
Celiac disease is an immune-mediated enteropathy caused by a permanent sensitivity to gluten in genetically susceptible individuals. It occurs in symptomatic subjects with gastrointestinal and …
Celiac Disease and Nonceliac Gluten SensitivityA Review
IMPORTANCE The prevalence of gluten-related disorders is rising, and increasing numbers of individuals are empirically trying a gluten-free diet for a variety of signs and symptoms. This …
Celiac disease: mechanisms and emerging therapeutics
Celiac disease (CeD) is a widespread, gluten-induced, autoimmune disorder that lacks any medicinal therapy. Towards the goal of developing non-dietary treat-ments for CeD, research …
Lessons from rodent models in celiac disease - Nature
Herein, we review how approaches in rodents have provided insight into celiac disease pathophysiology and also highlight the difficulties met to fully recapitulate the human disease.
Celiac Disease: The Evolutionary Paradox - Science and …
2. Physiology of Celiac Disease Celiac disease, also called gluten-sensitive enteropathy, is a chronic inflammatory disease of the small intestine that can develop in genetically-susceptible …
Celiac Disease: Should we care about microbes?
Jun 12, 2019 · Here, we discuss the evidence regarding the role of microbes in promoting CeD, 17 and the specific pathways triggered by microbes that could participate in CeD pathogenesis. …
Celiac Disease: Common Questions and Answers - AAFP
Celiac disease is an immune-mediated, multisystem disorder that affects genetically susceptible individuals who are exposed to gluten-containing grains such as wheat, barley, and rye.
Overview and Pathogenesis of Celiac Disease
Celiac disease is characterized by small intestinal mu- cosal injury and nutrient malabsorption in geneti-cally susceptible individuals following the dietary inges-tion of “gluten.”
Measuring Change In Small Intestinal Histology In Patients …
Subjective methods to grade celiac disease histological severity include the Marsh-Oberhuber and Corazza-Villanacci systems. Quantitative histology uses villus height (Vh), crypt depth (Cd), …
WHAT IS CELIAC DISEASE? - Celiac Canada
CELIAC DISEASE? Celiac disease (CD) is a permanent intolerance to gluten, a protein found in various wheat, rye, barley and triticale. Gluten consumption damages the small intestine and …
Identification of Food-grade Subtilisins as Gluten-degrading …
Jul 28, 2016 · The disease is characterized by inflammation and flattening of the 70 duodenal and jejunal villi, with a broad spectrum of symptoms, ranging from a clinically silent disease to 71 …
Celiac Disease and Imbalance of Intestinal Flora
Celiac disease is an autoimmune pathology of a genetic nature triggered by the consumption of gluten and characterized by histological changes in the intestine of genetically arranged …
Hematologic Manifestations of Celiac Disease - IntechOpen
Celiac disease is a systemic disease, which is associated with a number of hematologic manifestations. Individuals can present with hematological abnormalities even prior to the …
NIH Consensus Statement on Celiac Disease
• How is celiac disease diagnosed? • How prevalent is celiac disease? • What are the manifestations and long-term consequences of celiac disease? • Who should be tested for …
Gut microbiome investigation in celiac disease: from …
role in human physiology, and its alteration (“dysbiosis”) has been linked to a variety of inflammatory gut diseases, including celiac disease (CD). CD is a chronic, immune-mediated …
Celiac disease: should we care about microbes?
Apr 10, 2019 · Here, we discuss the evidence regarding the role of microbes in promoting CeD and the specific pathways triggered by microbes that could participate in CeD pathogenesis. …
Celiac Disease: Diagnosis and Management - AAFP
Celiac disease is characterized by chronic inflammation of the small intestinal mucosa, which leads to atrophy of the small intestinal villi and subsequent malabsorption. The condition...
Despite sequence homologies to gluten, salivary proline-rich …
May 20, 2015 · CELIAC DISEASE (CD) is a T cell-mediated inflammatory enter-opathy that manifests itself in genetically predisposed individ-uals. In its etiology, both genetic and …
Identification of food-grade subtilisins as gluten-degrading …
May 5, 2016 · First published July 28, 2016; doi:10.1152/ajpgi.00185.2016.—Gluten are proline- and glutamine-rich proteins present in wheat, barley, and rye and contain the immunogenic …