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| cell and developmental biology: Molecular Biology of the Cell , 2002 |
| cell and developmental biology: Molecular Cell Biology Harvey F. Lodish, 2000 With its acclaimed author team, cutting-edge content, emphasis on medical relevance, and coverage based on landmark experiments, Molecular Cell Biology has justly earned an impeccable reputation as an authoritative and exciting text. The new Sixth Edition features two new coauthors, expanded coverage of immunology and development, and new media tools for students and instructors. |
| cell and developmental biology: Mammalian Development Patrick P. L. Tam, W. James Nelson, Janet Rossant, 2013 A subject collection from Cold Spring Harbor perspectives in biology. |
| cell and developmental biology: Evo-Devo: Non-model Species in Cell and Developmental Biology Waclaw Tworzydlo, Szczepan M. Bilinski, 2019-10-09 Evolutionary developmental biology or evo-devo is a field of biological research that compares the underlying mechanisms of developmental processes in different organisms to infer the ancestral condition of these processes and elucidate how they have evolved. It addresses questions about the developmental bases of evolutionary changes and evolution of developmental processes. The book’s content is divided into three parts, the first of which discusses the theoretical background of evo-devo. The second part highlights new and emerging model organisms in the evo-devo field, while the third and last part explores the evo-devo approach in a broad comparative context. To the best of our knowledge, no other book combines these three evo-devo aspects: theoretical considerations, a comprehensive list of emerging model species, and comparative analyses of developmental processes. Given its scope, the book will offer readers a new perspective on the natural diversity of processes at work in cells and during the development of various animal groups, and expand the horizons of seasoned and young researchers alike. |
| cell and developmental biology: Cell Biology E-Book Thomas D. Pollard, William C. Earnshaw, Jennifer Lippincott-Schwartz, Graham Johnson, 2016-11-01 The much-anticipated 3rd edition of Cell Biology delivers comprehensive, clearly written, and richly illustrated content to today's students, all in a user-friendly format. Relevant to both research and clinical practice, this rich resource covers key principles of cellular function and uses them to explain how molecular defects lead to cellular dysfunction and cause human disease. Concise text and visually amazing graphics simplify complex information and help readers make the most of their study time. - Clearly written format incorporates rich illustrations, diagrams, and charts. - Uses real examples to illustrate key cell biology concepts. - Includes beneficial cell physiology coverage. - Clinically oriented text relates cell biology to pathophysiology and medicine. - Takes a mechanistic approach to molecular processes. - Major new didactic chapter flow leads with the latest on genome organization, gene expression and RNA processing. - Boasts exciting new content including the evolutionary origin of eukaryotes, super resolution fluorescence microscopy, cryo-electron microscopy, gene editing by CRISPR/Cas9, contributions of high throughput DNA sequencing to understand genome organization and gene expression, microRNAs, IncRNAs, membrane-shaping proteins, organelle-organelle contact sites, microbiota, autophagy, ERAD, motor protein mechanisms, stem cells, and cell cycle regulation. - Features specially expanded coverage of genome sequencing and regulation, endocytosis, cancer genomics, the cytoskeleton, DNA damage response, necroptosis, and RNA processing. - Includes hundreds of new and updated diagrams and micrographs,plus fifty new protein and RNA structures to explain molecular mechanisms in unprecedented detail. - Student Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and over a dozen animations from the book on a variety of devices. |
| cell and developmental biology: Developmental Biology: A Very Short Introduction Lewis Wolpert, 2011-08-25 A concise account of what we know about development discusses the first vital steps of growth and explores one of the liveliest areas of scientific research.--P. [2] of cover. |
| cell and developmental biology: Developmental Biology Norman John Berrill, 1971 |
| cell and developmental biology: Molecular Biology of the Cell 6E - The Problems Book John Wilson, Tim Hunt, 2014-11-21 The Problems Book helps students appreciate the ways in which experiments and simple calculations can lead to an understanding of how cells work by introducing the experimental foundation of cell and molecular biology. Each chapter reviews key terms, tests for understanding basic concepts, and poses research-based problems. The Problems Book has be |
| cell and developmental biology: The Molecular Biology of Cell Determination and Cell Differentiation Leon W. Browder, 2012-12-06 This series was established to create comprehensive treatises on specific topics in developmental biology. Such volumes serve a useful role in developmental biology, which is a very diverse field that receives contributions from a wide variety of disciplines. This series is a meeting ground for the various practi tioners of this science, facilitating an integration of heterogeneous information on specific topics. Each volume is comprised of chapters selected to provide the conceptual basis for a comprehensive understanding of its topic as well as an analysis of the key experiments upon which that understanding is based. The specialist in any aspect of developmental biology should understand the experimental back ground of the specialty and be able to place that body of information in context, in order to ascertain where additional research would be fruitful. The creative process then generates new experiments. This series is intended to be a vital link in that ongoing process of learning and discovery. |
| cell and developmental biology: Essays on Developmental Biology Part B Paul Wassarman, 2016-03-10 In 2016 Current Topics in Developmental Biology (CTDB) will celebrate its 50th or golden anniversary. To commemorate the founding of CTDB by Aron Moscona (1921-2009) and Alberto Monroy (1913-1986) in 1966, a two-volume set of CTDB (volumes 116 and 117), entitled Essays on Development, will be published by Academic Press/Elsevier in early 2016. The volumes are edited by Paul M. Wassarman, series editor of CTDB, and include contributions from dozens of outstanding developmental biologists from around the world. Overall, the essays provide critical reviews and discussion of developmental processes for a variety of model organisms. Many essays relate the history of a particular area of research, others personal experiences in research, and some are quite philosophical. Essays on Development provides a window onto the rich landscape of contemporary research in developmental biology and should be useful to both students and investigators for years to come. - Covers the area of developmental processes for a variety of model organisms - International board of authors - Part of two 50th Anniversary volumes proving a comprehensive set of reviews edited by Serial Editor Paul M. Wassarman |
| cell and developmental biology: Essential Developmental Biology Jonathan M. W. Slack, 2012-09-26 Essential Developmental Biology is a comprehensive, richly illustrated introduction to all aspects of developmental biology. Written in a clear and accessible style, the third edition of this popular textbook has been expanded and updated In addition, an accompanying website provides instructional materials for both student and lecturer use, including animated developmental processes, a photo gallery of selected model organisms, and all artwork in downloadable format. With an emphasis throughout on the evidence underpinning the main conclusions, this book is an essential text for both introductory and more advanced courses in developmental biology. Shortlisted for the Society of Biology Book Awards 2013 in the Undergraduate Textbook category. Reviews of the Second Edition: The second edition is a must have for anyone interested in development biology. New findings in hot fields such as stem cells, regeneration, and aging should make it attractive to a wide readership. Overall, the book is concise, well structured, and illustrated. I can highly recommend it. —Peter Gruss, Max Planck Society I have always found Jonathan Slack's writing thoughtful, provocative, and engaging, and simply fun to read. This effort is no exception. Every student of developmental biology should experience his holistic yet analytical view of the subject. —Margaret Saha, College of William & Mary |
| cell and developmental biology: Developmental Biology and Musculoskeletal Tissue Engineering Martin J. Stoddart, April M. Craft, Girish Pattappa, Oliver F.W. Gardner, 2018-04-24 Developmental Biology and Musculoskeletal Tissue Engineering: Principles and Applications focuses on the regeneration of orthopedic tissue, drawing upon expertise from developmental biologists specializing in orthopedic tissues and tissue engineers who have used and applied developmental biology approaches. Musculoskeletal tissues have an inherently poor repair capacity, and thus biologically-based treatments that can recapitulate the native tissue properties are desirable. Cell- and tissue-based therapies are gaining ground, but basic principles still need to be addressed to ensure successful development of clinical treatments. Written as a source of information for practitioners and those with a nascent interest, it provides background information and state-of-the-art solutions and technologies. Recent developments in orthopedic tissue engineering have sought to recapitulate developmental processes for tissue repair and regeneration, and such developmental-biology based approaches are also likely to be extremely amenable for use with more primitive stem cells. - Brings the fields of tissue engineering and developmental biology together to explore the potential for regenerative medicine-based research to contribute to enhanced clinical outcomes - Initial chapters provide an outline of the development of the musculoskeletal system in general, and later chapters focus on specific tissues - Addresses the effect of mechanical forces on the musculoskeletal system during development and the relevance of these processes to tissue engineering - Discusses the role of genes in the development of musculoskeletal tissues and their potential use in tissue engineering - Describes how developmental biology is being used to influence and guide tissue engineering approaches for cartilage, bone, disc, and tendon repair |
| cell and developmental biology: Digital Microscopy Greenfield Sluder, David E. Wolf, 2007-04-26 The previous edition of this book marked the shift in technology from video to digital camera use with microscope use in biological science. This new edition presents some of the optical fundamentals needed to provide a quality image to the digital camera. Specifically, it covers the fundamental geometric optics of finite- and infinity-corrected microscopes, develops the concepts of physical optics and Abbe's theory of image formation, presents the principles of Kohler illumination, and finally reviews the fundamentals of fluorescence and fluorescence microscopy. The second group of chapters deals with digital and video fundamentals: how digital and video cameras work, how to coordinate cameras with microscopes, how to deal with digital data, the fundamentals of image processing, and low light level cameras. The third group of chapters address some specialized areas of microscopy that allow sophisticated measurements of events in living cells that are below the optical limits of resolution. - Expands coverage to include discussion of confocal microscopy not found in the previous edition - Includes traps and pitfalls as well as laboratory exercises to help illustrate methods |
| cell and developmental biology: Essentials of Stem Cell Biology Robert Lanza, John Gearhart, Brigid Hogan, Douglas Melton, Roger Pedersen, E. Donnall Thomas, James A. Thomson, Ian Wilmut, 2009-06-05 First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest advances in stem cells. Representing the combined effort of seven editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world's experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, methods to application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered. - Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries - Contributions by Nobel Laureates and leading international investigators - Includes two entirely new chapters devoted exclusively to induced pluripotent stem (iPS) cells written by the scientists who made the breakthrough - Edited by a world-renowned author and researcher to present a complete story of stem cells in research, in application, and as the subject of political debate - Presented in full color with glossary, highlighted terms, and bibliographic entries replacing references |
| cell and developmental biology: Cell Movements Dennis Bray, 2001 This book vividly describes how complex and integrated movements can arise from the properties and behaviors of biological molecules. It provides a uniquely integrated account in which the latest findings from biophysics and molecular biology are put into the context of living cells. This second edition is updated throughout with recent advances in the field and has a completely revised and redrawn art program. The text is suitable for advanced undergraduates, graduate students, and for professionals wishing for an overview of this field. |
| cell and developmental biology: Scientific Frontiers in Developmental Toxicology and Risk Assessment National Research Council, Commission on Life Sciences, Board on Environmental Studies and Toxicology, Committee on Developmental Toxicology, 2000-12-21 Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians. |
| cell and developmental biology: Plant Development and Evolution , 2019-01-04 Plant Development and Evolution, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on the Evolution of the plant body plan, Lateral root development and its role in evolutionary adaptation, the Development of the vascular system, the Development of the shoot apical meristem and phyllotaxis, the Evolution of leaf diversity, the Evolution of regulatory networks in land plants, The role of programed cell death in plant development, the Development and evolution of inflorescence architecture, the Molecular regulation of flower development, the Pre-meiotic another development, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Current Topics in Developmental Biology series - Updated release includes the latest information on Plant Development and Evolution |
| cell and developmental biology: Planar Cell Polarization during Development Marek Mlodzik, 2005-08-02 Cellular polarization is key to all cellular functions. Our perceptions, which are derived from our senses, depend on the proper cellular polarization of our sense organs, such as the eyes or ears. Much of this book examines the different aspects in cellular polarization and its researched role in the Drosophila, where the first planar cellular polarity (PCP) gene was discovered over 20 years ago. Topics also include: From flies to man: how we are polarized, Marking an embryo work, Cellular polarization at its functional best, Hearing and seeing your environment, and From a cell to an organ.This series represents timely issues in developmental biology. It provides annual reviews of selected topics, written from the perspectives of leading investigators in the field of development.* Presents many various organisms such as flies, fish, frogs and mice* Offers over 40 exceptional illustrations* First of its kind to include new data and detailed models on cell planar polarization |
| cell and developmental biology: Principles of Cell Biology George Plopper, Diana Bebek Ivankovic, 2020-02-03 Principles of Cell Biology, Third Edition is an educational, eye-opening text with an emphasis on how evolution shapes organisms on the cellular level. Students will learn the material through 14 comprehensible principles, which give context to the underlying theme that make the details fit together. |
| cell and developmental biology: Applied Cell and Molecular Biology for Engineers Gabi Nindl Waite, Lee R.Waite, |
| cell and developmental biology: Stem Cells and the Future of Regenerative Medicine Institute of Medicine, Board on Neuroscience and Behavioral Health, National Research Council, Division on Earth and Life Studies, Board on Life Sciences, Committee on the Biological and Biomedical Applications of Stem Cell Research, 2002-01-25 Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€specifically embryonic stem cell researchâ€into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues. |
| cell and developmental biology: Essential Developmental Biology Jonathan M. W. Slack, 2009-03-12 TO ACCESS THE DEDICATED TEXTBOOK WEBSITE, PLEASE VISIT www.blackwellpublishing.com/slack Essential Developmental Biology, 2nd Edition, is a concise and well-illustrated treatment of this subject for undergraduates. With an emphasis throughout on the evidence underpinning the main conclusions, this book is suitable as the key text for both introductory and more advanced courses in developmental biology. Includes new chapters on Evolution & Development, Gut Development, & Growth and Aging. Contains expanded treatment of mammalian fertilization, the heart and stem cells. Now features a glossary, notated further reading, and key discovery boxes. Illustrated with over 250 detailed, full-color drawings. Accompanied by a dedicated website, featuring animated developmental processes, a photo gallery of selected model organisms, and all art in PowerPoint and jpeg formats (also available to instructors on CD-ROM). An Instructor manual CD-ROM for this title is available. Please contact our Higher Education team at HigherEducation@wiley.com for more information. |
| cell and developmental biology: The Neuron Irwin B. Levitan, Leonard K. Kaczmarek, 2002 Intended for use by advanced undergraduate, graduate and medical students, this book presents a study of the unique biochemical and physiological properties of neurons, emphasising the molecular mechanisms that generate and regulate their activity. |
| cell and developmental biology: Cell and Molecular Biology of Breast Cancer Heide Schatten, 2013-09-27 Highlighting recent advances in our understanding of breast cancer, this book is intended for a wide audience as a reference book. Included are reviews of genetics, epigenetics, various aspects of cell and molecular biology, and several other areas of breast cancer that are aimed at determining new intervention sites for treatments and cures of the disease. The chapters are written by internationally recognized experts and include reviews of key topics in breast cancer research. Each chapter highlights the new aspects of specific research topics and the various impacts of designing new strategies as well as identifies new targets for therapeutic intervention. The topics addressed are selected to be of interest to patients, scientists, students, teachers, and anyone else interested in expanding their knowledge of breast cancer imaging, diagnostics, therapeutics, or basic biomedical research on breast cancer. |
| cell and developmental biology: Human Embryology and Developmental Biology Bruce M. Carlson, MD, PhD, 2013-03-06 Master the concepts you need to know with Human Embryology and Developmental Biology. Dr. Bruce M. Carlson's clear explanations provide an easy-to-follow road map through the most up-to-date scientific knowledge, giving you a deeper understanding of the key information you need to know for your courses, exams, and ultimately clinical practice. Visualize normal and abnormal development with hundreds of superb clinical photos and embryological drawings. Access the fully searchable text online, view animations, answer self-assessment questions, and much more at www.studentconsult.com. Grasp the molecular basis of embryology, including the processes of branching and folding - essential knowledge for determining the root of many abnormalities. Understand the clinical manifestations of developmental abnormalities with clinical vignettes and Clinical Correlations boxes throughout. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued. |
| cell and developmental biology: The Cell Biology of Stem Cells Eran Meshorer, Kathrin Plath, 2011-01-11 Stem cells have been gaining a lot of attention in recent years. Their unique potential to self-renew and differentiate has turned them into an attractive model for the study of basic biological questions such as cell division, replication, transcription, cell fate decisions, and more. With embryonic stem (ES) cells that can generate each cell type in the mammalian body and adult stem cells that are able to give rise to the cells within a given lineage, basic questions at different developmental stages can be addressed. Importantly, both adult and embryonic stem cells provide an excellent tool for cell therapy, making stem cell research ever more pertinent to regenerative medicine. As the title The Cell Biology of Stem Cells suggests, our book deals with multiple aspects of stem cell biology, ranging from their basic molecular characteristics to the in vivo stem cell trafficking of adult stem cells and the adult stem-cell niche, and ends with a visit to regeneration and cell fate reprogramming. In the first chapter, “Early embryonic cell fate decisions in the mouse”, Amy Ralson and Yojiro Yamanaka describe the mechanisms that support early developmental decisions in the mouse pre-implantation embryo and the current understanding of the source of the most immature stem cell types, which includes ES cells, trophoblast stem (TS) cells and extraembryonic endoderm stem (XEN) cells. |
| cell and developmental biology: Principles of Cellular, Molecular, and Developmental Neuroscience Oswald Steward, 2012-12-06 The field of cellular, molecular, and developmental neuroscience repre sents the interface between the three large, well established fields of neu roscience, cell biology, and molecular biology. In the last 10 to 15 years, this new field has emerged as one of the most rapidly growing and exciting subdisciplines of neuroscience. It is now becoming possible to understand many aspects of nervous system function at the molecular level, and there already are dramatic applications of this information to the treatment of nervous system injury, disease, and genetic disorders. Moreover, there is great optimism that new strategies will emerge soon as a result of the explosion of information. This book was written to introduce students to the major issues, ex perimental strategies, and current knowledge base in cellular, molecular, and developmental neuroscience. The concept for the book arose from a section of an introductory neuroscience course given to first-year medical students at the University of Virginia School of Medicine. The text pre sumes a basic, but not detailed, understanding of nervous system orga nization and function, and a background in biology. It is intended as an appropriate introductory text for first-year medical students or graduate students in neuroscience, neurobiology, psychobiology, or related pro grams;··and for advanced undergraduate students with appropriate back ground in biology and neuroscience. While some of the specific information presented undoubtedly will be outdated rapidly, the gestalt of this emerging field of inquiry as presented here should help the beginning stu dent organize new information. |
| cell and developmental biology: Euglena: Biochemistry, Cell and Molecular Biology Steven D. Schwartzbach, Shigeru Shigeoka, 2017-04-19 This much-needed book is the first definitive volume on Euglena in twenty-fire years, offering information on its atypical biochemistry, cell and molecular biology, and potential biotechnology applications. This volume gathers together contributions from well-known experts, who in many cases played major roles in elucidating the phenomenon discussed. Presented in three parts, the first section of this comprehensive book describes novel biochemical pathways which in some instances have an atypical subcellular localization. The second section details atypical cellular mechanisms of organelle protein import, organelle nuclear genome interdependence, gene regulation and expression that provides insights into the evolutionary origins of eukaryotic cells. The final section discusses how biotechnologists have capitalized on the novel cellular and biochemical features of Euglena to produce value added products. Euglena: Biochemistry, Cell and Molecular Biology will provide essential reading for cell and molecular biologists with interests in evolution, novel biochemical pathways, organelle biogenesis and algal biotechnology. Readers will come away from this volume with a full understanding of the complexities of the Euglena as well as new realizations regarding the diversity of cellular processes yet to be discovered. |
| cell and developmental biology: Echinoderms , 2019-02-16 Echinoderms, Volume 150 in the Methods in Cell Biology series, highlights new advances in the field, with this update presenting interesting chapters on procuring animals and culturing of eggs and embryos, cryopreservation of sea urchin gametes, emerging echinoderm models, culturing of sand dollars, cidaroids and heart urchins, culturing echinoderm larvae through metamorphosis, microinjection methods, injection of exogenous messages and protein overexpression, blastomere transplantation, visualization of embryonic polarity, larval immune cell approaches, methods for analysis of sea urchin primordial germ cells, and protocols and best practices for toxicology and pH studies using echinoderms and several new chapters outlining the use of sea urchins in the classroom. - Clear, concise protocols provided by experts who have established the echinoderms as a model system - Highlights new advances in the field, with this update presenting interesting chapters on echinoderms |
| cell and developmental biology: Immunology and Developmental Biology of the Chicken Olli Vainio, Beat A. Imhof, 2012-12-06 Books on both chicken immunology and developmental biology are rare. This one, however, summarizes all aspects of both areas and therefore represents a valuable compendium for experienced researchers as well as for all newcomers to the field. Following a lengthy discussion of the origin of hemopoietic cells, regulatory elements for the differentiation of these cells and B and T cell lymphopoiesis, the book goes on to describe the generation of transgenic chickens as well as an additional basic feature in embryogenesis: the positioning of organ anlage, e.g. the limb bud. To round off, a valuable compilation of monoclonal antibodies further enhances the practical usefulness of this important book. |
| cell and developmental biology: The Digital Cell Stephen J. Royle, 2019 Cell biology is becoming an increasingly quantitative field, as technical advances mean researchers now routinely capture vast amounts of data. This handbook is an essential guide to the computational approaches, image processing and analysis techniques, and basic programming skills that are now part of the skill set of anyone working in the field-- |
| cell and developmental biology: Hematopoietic Stem Cell Biology Motonari Kondo, 2009-12-04 In the summer of 1988, my developmental biology professor announced to the class that hematopoietic stem cells (HSCs) had finally been purified. Somehow, I never forgot the professor’s words. When I started working in Dr. Irv Weissman’s labo- tory at Stanford as a postdoctoral fellow, I realized that the findings mentioned by the professor were from Weissman’s laboratory and had been published in a 1988 edition of the journal Science. It has been over 20 years since the publication of that seminal paper, and since then tremendous advances in understanding the biology and maturation of HSCs, namely the process of hematopoiesis, which includes lymphocyte development, have been made. These discoveries were made possible in part by advancements in technology. For example, recent availability of user friendly fluorescence activated cell sorting (FACS) machines and monoclonal an- bodies with a variety of fluorescent labels has allowed more scientists to sort and analyze rare populations in the bone marrow, such as HSCs. All classes of hematopoietic cells are derived from HSCs. Stem cell biology draws enormous attention not only from scientists, but also from ordinary people because of the tremendous potential for development of new therapeutic application to diseases that currently lack any type of effective therapy. Thus, this type of “regenerative medicine” is a relatively new and attractive field in both basic science and clinical medicine. |
| cell and developmental biology: Forces in Biology - Cell and Developmental Mechanobiology and Its Implications in Disease Selwin K. Wu, Michael Smutny, Samantha J. Stehbens, Guillermo A. Gomez, 2020-12-11 |
| cell and developmental biology: International Review of Cell and Molecular Biology Kwang W. Jeon, 2014-11-18 International Review of Cell and Molecular Biology presents comprehensive reviews and current advances in cell and molecular biology. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. The series has a world-wide readership, maintaining a high standard by publishing invited articles on important and timely topics authored by prominent cell and molecular biologists. - Authored by some of the foremost scientists in the field - Provides comprehensive reviews and current advances - Wide range of perspectives on specific subjects - Valuable reference material for advanced undergraduates, graduate students and professional scientists |
| cell and developmental biology: Molecular Biology of B Cells Tasuku Honjo, Michael Reth, Andreas Radbruch, Frederick Alt, 2014-12-22 Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics. |
| cell and developmental biology: Cell Biology of Addiction Bertha Madras, 2006 This monograph, written by experts in the field, is devoted to the molecular analysis of addiction pathways in the brain. It provides an intensive overview of the fundamentals, state of the art advances, and major gaps in the cell and molecular biology of drug addiction within the broader context of neuroscience. Addiction research is a branch of neuroscience and psychology. The emphasis in this book is on hard science and the market for it will be found among research investigators and grad students within the field of neuroscience. The research presented is not only applicable to the study of drug abuse and addiction, but has clear implications for clarifying mechanisms of learning and memory, neuroadaptation, perception, volitional behavior, motivation, reward, and other disciplines of neuroscience. |
| cell and developmental biology: Experimental Design for Biologists David J. Glass, 2007 The effective design of scientific experiments is critical to success, yet graduate students receive very little formal training in how to do it. Based on a well-received course taught by the author, Experimental Design for Biologistsfills this gap. Experimental Design for Biologistsexplains how to establish the framework for an experimental project, how to set up a system, design experiments within that system, and how to determine and use the correct set of controls. Separate chapters are devoted to negative controls, positive controls, and other categories of controls that are perhaps less recognized, such as “assumption controls†and “experimentalist controls†. Furthermore, there are sections on establishing the experimental system, which include performing critical “system controls†. Should all experimental plans be hypothesis-driven? Is a question/answer approach more appropriate? What was the hypothesis behind the Human Genome Project? What color is the sky? How does one get to Carnegie Hall? The answers to these kinds of questions can be found in Experimental Design for Biologists. Written in an engaging manner, the book provides compelling lessons in framing an experimental question, establishing a validated system to answer the question, and deriving verifiable models from experimental data. Experimental Design for Biologistsis an essential source of theory and practical guidance in designing a research plan. |
| cell and developmental biology: Plant Developmental Biology Lars Hennig, Claudia Köhler, 2016-08-23 Plants come in myriads of shapes and colors, and the beauty of plants has fascinated mankind for thousands of years. Long before Mendel discovered the laws of heritab- ity and Darwin developed his theory on evolution, the affection for ornamental plants led people to select alleles that establish novel plant forms. Today, plant developmental biology tries to discover the mechanisms that control the establishment of specialized cell types, tissues, and organs from the fertilized egg during a plant’s life. Although the underlying processes of cell proliferation and differentiation are similar in plants and a- mals, plants are different because their development is usually open, and its outcome is not the faithful repetition of a general plan but is strongly in?uenced by environm- tal conditions. In the last few decades, plant developmental biology has pinpointed a large number of developmental regulators and their interactions and the mechanisms that govern plant development start to emerge. In part, this progress was enabled by the advance of powerful molecular tools for a few model species, most importantly Arabidopsis. This volume of the Methods in Molecular Biology series provides a collection of protocols for many of the common experimental approaches in plant developmental bi- ogy. All chapters are written in the same format as that used in the Methods in Molecular TM Biology series. Each chapter opens with a description of the basic theory behind the method being described. |
| cell and developmental biology: Principles of Development Lewis Wolpert, 1998 Developmental biology is at the core of all biology. This text emphasizes the principles and key developments in order to provide an approach and style that will appeal to students at all levels. |
| cell and developmental biology: Human Embryology & Developmental Biology Bruce M. Carlson, 1999 Combines an introduction to the molecular and mechanistic basis of human development with classic descriptive embryology. Presents the latest findings in the fields of genetics, cell biology, endocrinology, reproduction, pathology, and anatomy, discussing their effect on human developmental biology. Includes review question with answers. Annotation copyright by Book News, Inc., Portland, OR |
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Recent discoveries in stem cell and developmental biology have introduced a new era marked by the generation of in vitro models that recapitulate early mammalian development, providing...
Developmental and stem cell biology's bright future - Cell Press
Emerging advances in developmental biology are unlocking ways to transform human induced pluripotent stem cells (hiPSCs) into multicellular moieties, such as organoids, that contain the …
01:146:270 Fundamentals of Cell and Developmental Biology
Obtain factual and conceptual knowledge in fundamentals of cell biology and development (with a hint of neuroscience) that will provide a strong foundation for success in advanced training and …
DEPARTMENT OF MOLECULAR, CELLULAR
CELL AND DEVELOPMENTAL BIOLOGY MAJOR, B.S – 2022-2023 To be admitted to full major status, students must fulfill the pre-biology course and grade-point average requirements as …
Seminars in Cell & Developmental Biology - Institute for Stem …
Krumm, Z. Duan / Seminars in Cell & Developmental Biology 90 (2019) 62–77 63 Fig. 1. Hierarchical organization of the genome. Genomic DNA in the eukaryotic nucleus possesses …
On the evolutionary developmental biology of the cell - Cell …
Organisms are complex assemblages of cells, cells that produce light, shoot harpoons, and secrete glue. Therefore, identifying the mechanisms that gener-ate novelty at the level of the …
Plant Development Cell and Developmental Biology Part 1B
In these six lectures we will look at some striking features of biological self-organisation and morphogenesis using examples from the model plant, Arabidopsis thaliana. Plant cells are …
How developmental cell atlases inform stem cell embryo …
In vivo developmental atlases provide a crucial reference for the new class of stem-cell-derived human embryo models, helping accelerate insights into the mechanisms of human development.
Cell & Developmental Biology (MS) - Thomas Jefferson …
This program consists of a core basic science curriculum in cell and developmental biology, supplemented with elective courses suited to individual career interests in the basic sciences …
Developmental and Cell Biology, B.S. - catalogue.uci.edu
The Developmental and Cell Biology major is intended to provide students with intensive training in cutting edge approaches to understanding the structure and function of cells and how they …
What Is the Future of Developmental Biology? - Cell Press
Over the past decade, the gap between the technical difficulties in manipulating cultured cells versus embryos has nar-rowed significantly. This has enabled developmental biologists to …
Cell and Developmental Biology Module BS1003
What is Cell and Developmental Biology all about? o Cell functions – Grow – Divide – Synthesize molecules – Use energy – Generate energy – Interact with neighboring cells – Respond to …
The evolution of developmental biology through conceptual …
We describe how classic questions in gene regulation, pattern formation, morphogenesis, organogenesis, and stem cell biology are being revisited. We discuss the connections of …
Basic concepts of Development - Kunthavai Naacchiyaar …
Modern developmental biology studies the genetic control of cell growth, differentiation and "morphogenesis," which is the process that gives rise to tissues, organs and anatomy. All …
UNIT 3: DEVELOPMENTAL BIOLOGY
Gametogenesis occurs when a haploid cell (n) is formed from a diploid cell (2n) through meiosis. We call gametogenesis in the male spermatogenesis and it produces spermatozoa. In the …
Cell and developmental biology: grand challenges - Frontiers
Collectively our interests range from a desire to understand how cells develop, replicate, interact, and age to more complex problems concerning how multicellular tissues form and the …
Welcome to Biology 205 Section 6 – Introduction to Cell …
To provide you with the core principles of cell and developmental biology. The lectures and the book will introduce you to the fields of cell biology and developmental biology.
Chapter 1 The excitement of developmental biology - British …
Molecular and cell biology tell us about how individual genes and cells work. In development this means the operation of intercellular signaling factors, their receptors, intracellular signal …
Cell and Developmental Biology - longdom.org
Cell & Developmental Biology (CDB) is a broad-scope, official peer reviewed journal that publishes innovative research, which welcomes submissions on a wide spectrum of cell and …
Developmental Biology - Ace The Race
Fate of a cell is all the different cell types, its descendants can become during normal development. The developmental hierarchy is the hierarchical series of decisions involving …
A new era of stem cell and developmental biology: from
Recent discoveries in stem cell and developmental biology have introduced a new era marked by the generation of in vitro models that recapitulate early mammalian development, providing...
Developmental and stem cell biology's bright future - Cell …
Emerging advances in developmental biology are unlocking ways to transform human induced pluripotent stem cells (hiPSCs) into multicellular moieties, such as organoids, that contain the …
01:146:270 Fundamentals of Cell and Developmental Biology
Obtain factual and conceptual knowledge in fundamentals of cell biology and development (with a hint of neuroscience) that will provide a strong foundation for success in advanced training and …
DEPARTMENT OF MOLECULAR, CELLULAR
CELL AND DEVELOPMENTAL BIOLOGY MAJOR, B.S – 2022-2023 To be admitted to full major status, students must fulfill the pre-biology course and grade-point average requirements as …
Seminars in Cell & Developmental Biology - Institute for …
Krumm, Z. Duan / Seminars in Cell & Developmental Biology 90 (2019) 62–77 63 Fig. 1. Hierarchical organization of the genome. Genomic DNA in the eukaryotic nucleus possesses …
On the evolutionary developmental biology of the cell - Cell …
Organisms are complex assemblages of cells, cells that produce light, shoot harpoons, and secrete glue. Therefore, identifying the mechanisms that gener-ate novelty at the level of the …
Plant Development Cell and Developmental Biology Part 1B
In these six lectures we will look at some striking features of biological self-organisation and morphogenesis using examples from the model plant, Arabidopsis thaliana. Plant cells are …
How developmental cell atlases inform stem cell embryo …
In vivo developmental atlases provide a crucial reference for the new class of stem-cell-derived human embryo models, helping accelerate insights into the mechanisms of human development.
Cell & Developmental Biology (MS) - Thomas Jefferson …
This program consists of a core basic science curriculum in cell and developmental biology, supplemented with elective courses suited to individual career interests in the basic sciences …
Developmental and Cell Biology, B.S. - catalogue.uci.edu
The Developmental and Cell Biology major is intended to provide students with intensive training in cutting edge approaches to understanding the structure and function of cells and how they …
What Is the Future of Developmental Biology? - Cell Press
Over the past decade, the gap between the technical difficulties in manipulating cultured cells versus embryos has nar-rowed significantly. This has enabled developmental biologists to …
