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crohn's disease combination therapy: Advances in Inflammatory Bowel Diseases P. Rutgeerts, J-F. Colombel, S.B. Hanauer, J. Schölmerich, Guido Tytgat, A. van Gossum, 1998-12-31 Ulcerative colitis and Crohn's disease remain a great therapeutic challenge to the medical community. In recent years knowledge about the pathogenesis of these diseases has progressed rapidly but the cause of the diseases remains completely unknown. It has become clear that dysregulation of the mucosal immune system is the basis for the chronic evolution of the diseases in a genetically susceptible population. Exciting new therapeutic approaches have been attempted in the last couple of years and cytokine and anti-cytokine treatments in particular seem very promising, especially in intractable disease. The format of the Falk Symposium 106 on `Advances in Inflammatory Bowel Diseases', held in Brussels, Belgium, June 18-20, 1998, was somewhat innovative as each session attempted to link the new insights into pathogenetic mechanisms with new therapeutic approaches, resulting in optimal information transfer. The classic therapeutic schemes were updated with a special focus on step-wise build-up of therapy. |
crohn's disease combination therapy: Pediatric Inflammatory Bowel Disease Petar Mamula, Jonathan E. Markowitz, Robert N. Baldassano, 2012-12-14 Pediatric Inflammatory Bowel Disease, Second Edition provides an essential reference with an emphasis on the unique pediatric issues of IBD. Chapters focus on complications of IBD specific to children and adolescents. Treatment recommendations are based on the latest clinical research available. The textbook also presents sections dedicated to the aspects of participation in clinical research unique to children and adolescents and the complicated yet vital process of successfully transitioning a patient from a pediatric to adult specialist. Controversies in pediatric IBD care such as the off-label use of medications are also covered. The format incorporates multiple tables, graphs, and figures to improve readability and make for an efficient reference for clinicians to use. Thoroughly revised and updated from the first edition, the volumes includes new therapies that are currently being used or tested for treatment of IBD, important areas regarding incidence and prevalence, immunization and response to vaccine administration as well as advancements in our understanding of growth and development with particular to the use of growth hormone therapy. Other new areas covered include important topics of complementary and alternative medicine use in IBD, immunization, and liver disease in IBD. Pediatric Inflammatory Bowel Disease, Second Edition is a valuable resource for pediatric gastroenterologists as well as adult gastroenterologists. |
crohn's disease combination therapy: The ASCRS Manual of Colon and Rectal Surgery David E. Beck, John L. Rombeau, Michael J. Stamos, Steven D. Wexner, 2009-06-12 The ASCRS Textbook of Surgery of the Colon and Rectum offers a comprehensive textbook designed to provide state of the art information to residents in training and fully trained surgeons seeking recertification. The textbook also supports the mission of the ASCRS to be the world’s authority on colon and rectal disease. The combination of junior and senior authors selected from the membership of the ASCRS for each chapter will provide a comprehensive summary of each topic and allow the touch of experience to focus and temper the material. This approach should provide the reader with a very open minded, evidence based approach to all aspects of colorectal disease. Derived from the textbook, The ASCRS Manual of Surgery of the Colon and Rectum offers a “hands on” version of the textbook, written with the same comprehensive, evidence-based approach but distilled to the clinical essentials. In a handy pocket format, readers will find the bread and butter information for the broad spectrum of practice. In a consistent style, each chapter outlines the condition or procedure being discussed in a concise outline format – easy to read, appropriately illustrated and referenced. |
crohn's disease combination therapy: Crohn's Disease and Ulcerative Colitis Daniel C. Baumgart, 2017-03-01 This new edition is a unique combined resource for physicians and scientists addressing the needs of both groups. In addition to stimulating exchange and collaboration and shortening the path between discovery and application of new knowledge, the book helps clinicians understand new therapeutic concepts from their origins. The volume serves as a comprehensive guide to the current diagnostic modalities, including enhanced imaging techniques such as MRI and CT enterography, virtual colonoscopy, ultrasound, and endomicroscopy, as well as conventional and complex immunomodulatory principles. The latest edition also includes revised chapters from the previous edition, as well as new chapters reflecting current developments in the field. Written by experts in their field, Crohn’s Disease and Ulcerative Colitis: From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach, Second Edition is of great value to gastroenterologists, surgeons, internists, pediatricians and gynecologists trainees, as well as all those involved in Crohn’s disease, ulcerative colitis, and related autoimmune disorders. |
crohn's disease combination therapy: Endoscopy in Inflammatory Bowel Disease Richard Kozarek, Michael Chiorean, Michael Wallace, 2014-11-03 This book conjoins the latest advances on the use of endoscopy to diagnose, monitor, and treat patients with inflammatory bowel disease. Chapters include the historical use of rigid sigmoidoscopy, non-interventional imaging procedures, and the correlation of pathology and endoscopic visualization. This is the first book to include individual chapters in gastroenterology, colorectal surgery, and IBD texts, the preeminent role of endoscopic imaging in the management of chronic ulcerative colitis, and Crohn's disease. It also includes chapters on capsule endoscopy and balloon and overtube-assisted enteroscopy to define the presence and activity of Crohn's enteritis and additional chapters defining the use of random biopsies versus chromoendoscopy, and computer enhanced imaging to define possible dysplasia development. The book also includes access to online videos, making it the ultimate verbal and visual tool for all medical professionals interested in the advances in the field over the last several decades. Endoscopy in Inflammatory Bowel Disease is a concise text that is of great value to practicing endoscopists, gastroenterologists, general or colorectal surgeons, physicians in training, and all medical professionals caring for patients with inflammatory bowel disease. |
crohn's disease combination therapy: Harrison's Principles of Internal Medicine Tinsley Randolph Harrison, 1998 Classic text for practitioners, residents, and students. |
crohn's disease combination therapy: Therapy for Severe Psoriasis E-Book Jashin J. Wu, Steven R. Feldman, Mark Lebwohl, 2016-12-02 A brand-new title in the field of dermatology, Therapy for Severe Psoriasis provides the ultimate coverage of the treatment options available for today's most serious cases, including biologics and oral therapies. It features discussions of the newest drug therapies, recent FDA-approved biosimilars, and combination approaches to care, while an overview chapter was designed to aid those new to the field in understanding the nuances of difficult-to-treat subtypes of psoriasis. Comprehensive and focused, Therapy for Severe Psoriasis will be a welcome addition to the library of any dermatologist seeking in-depth information on the challenges of this condition. - Each of the 16 chapters includes either an in-depth focus on a single therapy or an overview of a unique aspect of psoriasis, including: UVB therapy, methotrexate, acitretin, cyclosporine, apremilast, etanercept, infliximab, adalimumab, ustekinumab, secukinumab, and ixekizumab. - Takes an evidence-based approach to hard-to-treat severe psoriasis. - Discusses the newest drug therapies (such as ixekizumab), plus recent FDA-approved biosimilars, a topic unique to this particular psoriasis text. - Presents combination approaches for instances when standard treatments are not successful. - Includes an overview chapter to help beginners understand the nuances of the disorder. |
crohn's disease combination therapy: Therapeutic Immunosuppression Angus W. Thomson, 2001 This work has broad applications in clinical medicine, ranging from prevention and treatment of organ and bone marrow transplant rejection, management of various autoimmune disorders (for example, rheumatoid arthritis), skin disease and asthma. Whereas traditionally only a small repertoire of immunosuppressive agents was available for clinical use, recent discoveries have significantly increased the number of approved agents, resulting in numerous trials to further evaluate their potential. There is also considerable interest in the potential of cell-based therapies (particularly hematopoietic stem and dendritic cell therapy) of allo- and autoimmunity. Important recent advances in the immunotherapy of allergic diseases are also covered in this book. This volume is intended both for practising physicians and surgeons and for biomedical scientists at the graduate/postdoctoral levels, and is designed to provide the theory behind these various approaches to immunosuppression, and to provide state-of-the-art reviews of current developments in each area. |
crohn's disease combination therapy: Paediatric Gastroenterology, Hepatology and Nutrition Mark Beattie, Anil Dhawan, John WL Puntis, 2009-03-12 This handbook of paediatric gastroenterology, hepatology and nutrition provides a concise overview of key topics in these three closely related specialties. |
crohn's disease combination therapy: The ASCRS Textbook of Colon and Rectal Surgery Scott R. Steele, Tracy L. Hull, Thomas E. Read, Theodore J. Saclarides, Anthony J. Senagore, Charles B. Whitlow, 2016-03-24 This third edition text provides a completely revised and updated new version of this unique, modern, practical text that covers the strategic evaluation, specific approaches, and detailed management techniques utilized by expert colorectal surgeons caring for patients with complex problems–whether they result from underlying colorectal disease or from complications arising from previous surgical therapy. The format follows that of both a “how to” manual as well as an algorithm-based guide to allow the reader to understand the thought process behind the proposed treatment strategy. By making use of evidence-based recommendations, each chapter includes not only background information and diagnostic/therapeutic guidelines, but also provides a narrative by the author on his/her operative technical details and perioperative “tips and tricks” that they utilize in the management of these complex surgical challenges. Distinctive to this book, is the reliance on experts in the field including past presidents of the ASCRS, as well as multiple other national and internationally recognized surgeons, to lend their personal insight into situations where data may be more sparse, but individual and collective experience is paramount to making sound decisions and thereby optimizing patient outcomes. The text includes chapters on the assessment of risk and methods utilized to minimize perioperative complications. In addition, it incorporates sections covering the medical and surgical therapies for abdominal, pelvic and anorectal disease. Moreover, the technical challenges of managing complications resulting from the original or subsequent operations is addressed. The underlying focus throughout the text is on providing pragmatic and understandable solutions that can be readily implemented by surgeons of varying experience to successfully treat complex colorectal problems. However, it also goes beyond the technical aspects of colorectal surgery and includes special sections highlighting the essence of a surgeon; covering aspects involving the medical-legal, ethical, and economic challenges confronting surgeons. Throughout the text, each author provides an ongoing narrative of his/her individual surgical techniques along with illustrations and diagrams to “personally” take the reader through the crucial steps of the procedure, and key points of patient care inherent to that topic. Additionally, where appropriate, links to online videos give the reader an up-front look into technical aspects of colorectal surgery. |
crohn's disease combination therapy: Selective Immunosuppression Luciano Adorini, 1995 |
crohn's disease combination therapy: Inflammatory Bowel Disease Stephan R. Targan, Fergus Shanahan, Loren C. Karp, 2011-08-24 This is the state-of–the-art book on inflammatory bowel disease you have been waiting for Written and edited by international experts in gastroenterology this up-to-date volume provides a complete review of the basic science behind inflammatory bowel disease (IBD), as well as evidence-based clinical guidance on diagnosis, treatment and long-term management of IBD. In 50 chapters the authors cover the latest and most promising treatment modalities and the science behind them. There are chapters which cover the advances in the medical and surgical treatment of conditions such as Crohn's disease and ulcerative colitis, as well as chapters focusing on nutrition, imaging and complementary medicine. This is an invaluable information resource for all those in the medical team treating patients with IBD. Whether you are a gastroenterologist, gastrointestinal surgeon or GI nurse specialist this book deserves a place in your library. |
crohn's disease combination therapy: Safe and Effective Medicines for Children Institute of Medicine, Board on Health Sciences Policy, Committee on Pediatric Studies Conducted Under the Best Pharmaceuticals for Children Act (BPCA) and the Pediatric Research Equity Act (PREA), 2012-10-13 The Best Pharmaceuticals for Children Act (BPCA) and the Pediatric Research Equity Act (PREA) were designed to encourage more pediatric studies of drugs used for children. The FDA asked the IOM to review aspects of pediatric studies and changes in product labeling that resulted from BPCA and PREA and their predecessor policies, as well as assess the incentives for pediatric studies of biologics and the extent to which biologics have been studied in children. The IOM committee concludes that these policies have helped provide clinicians who care for children with better information about the efficacy, safety, and appropriate prescribing of drugs. The IOM suggests that more can be done to increase knowledge about drugs used by children and thereby improve the clinical care, health, and well-being of the nation's children. |
crohn's disease combination therapy: Drug-Induced Liver Injury , 2019-07-13 Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series |
crohn's disease combination therapy: Clinical Practice Guidelines We Can Trust Institute of Medicine, Board on Health Care Services, Committee on Standards for Developing Trustworthy Clinical Practice Guidelines, 2011-06-16 Advances in medical, biomedical and health services research have reduced the level of uncertainty in clinical practice. Clinical practice guidelines (CPGs) complement this progress by establishing standards of care backed by strong scientific evidence. CPGs are statements that include recommendations intended to optimize patient care. These statements are informed by a systematic review of evidence and an assessment of the benefits and costs of alternative care options. Clinical Practice Guidelines We Can Trust examines the current state of clinical practice guidelines and how they can be improved to enhance healthcare quality and patient outcomes. Clinical practice guidelines now are ubiquitous in our healthcare system. The Guidelines International Network (GIN) database currently lists more than 3,700 guidelines from 39 countries. Developing guidelines presents a number of challenges including lack of transparent methodological practices, difficulty reconciling conflicting guidelines, and conflicts of interest. Clinical Practice Guidelines We Can Trust explores questions surrounding the quality of CPG development processes and the establishment of standards. It proposes eight standards for developing trustworthy clinical practice guidelines emphasizing transparency; management of conflict of interest ; systematic review-guideline development intersection; establishing evidence foundations for and rating strength of guideline recommendations; articulation of recommendations; external review; and updating. Clinical Practice Guidelines We Can Trust shows how clinical practice guidelines can enhance clinician and patient decision-making by translating complex scientific research findings into recommendations for clinical practice that are relevant to the individual patient encounter, instead of implementing a one size fits all approach to patient care. This book contains information directly related to the work of the Agency for Healthcare Research and Quality (AHRQ), as well as various Congressional staff and policymakers. It is a vital resource for medical specialty societies, disease advocacy groups, health professionals, private and international organizations that develop or use clinical practice guidelines, consumers, clinicians, and payers. |
crohn's disease combination therapy: Advances in Endoscopy in Inflammatory Bowel Disease Toshifumi Hibi, Tadakazu Hisamatsu, Taku Kobayashi, 2017-09-04 Advances in Endoscopy in Inflammatory Bowel Disease summarizes the recent progress made in endoscopy, an essential tool for the diagnosis and management of IBD. It goes on to provide an introduction of state-of-the-art endoscopic techniques, as well as an atlas of high-quality endoscopic images of IBD and related diseases. Among others, endoscopy is one of the clinical fields in which Asian countries are leading the way in the management of gastrointestinal disorders. As the number of patients with IBD is dramatically increasing in Asia, quality of patient care has been significantly improved. With diagnosis of intestinal Behcet, simple ulcers, and intestinal tuberculosis, which are unique to the Asian countries, this book offers the ideal standard textbook for IBD endoscopy in all Asian counties, while the superior quality of images also makes it a valuable resource for practitioners around the globe. This book will significantly help all physicians, endoscopists and researchers working on GI endoscopy, especially those focusing on IBD, to improve their knowledge of IBD endoscopy. |
crohn's disease combination therapy: Crohn's Disease and Ulcerative Colitis Fredric G. Saibil, 2011 Inflammatory bowel disease (IBD) includes two chronic conditions, Crohn's disease and ulcerative colitis. It has remained for too long the secret illness no one wants to admit to having, let alone discuss. One percent of the population has IBD, yet its cause is unknown and there is no known cure. Revised and updated, Crohn's Disease and Ulcerative Colitis is the complete practical guide for anyone dealing with inflammatory bowel disease. Fred Saibil, MD, a renowned expert on IBD, provides the most up-to-date, concise, critical and practical information on the common symptoms and side effects. He describes the normal gastrointestinal system and then explains what specifically goes wrong in those suffering from IBD. Crohn's Disease and Ulcerative Colitis includes important information on: * Why people get IBD, including the hygiene hypothesis, and new genetic data * Diagnostic methods, including enteroscopy, capsule endoscopy, CT, MR, and PET scans * Effects of diet, including foods and food components that can cause diarrhea and gas * Surgical options * The expanding choice of drugs, plus probiotics and prebiotics * Issues specific to children with IBD * Effects on sex, child-bearing and drug usage during pregnancy and breast-feeding * Self-management -- how to help your medical team help you * How to take care of your bones * How to cope with being in hospital. For patients, their relatives and caregivers, Crohn's Disease and Ulcerative Colitis explains the plain facts about this terrible disease, which seriously affects the daily lives of so many. |
crohn's disease combination therapy: Leukocyte Trafficking Alf Hamann, Britta Engelhardt, 2006-05-12 Written by known specialists in the field, this is a comprehensive and timely overview of a central and expanding topic. Simultaneously an introduction and a description of the latest concepts, findings and methods, the handbook provides basic knowledge on technical issues required for those intending to research in the field. It covers the functional role of involved molecules and the cellular mechanisms, and addresses selected examples for their possible application in therapy -- bridging the gap between trafficking mechanisms and novel therapeutic strategies. In addition, it includes selection of proven and timesaving methods for studying cell trafficking in vitro and in vivo. The accompanying CD-ROM makes leukocyte migration videos available to a broad audience for the first time. |
crohn's disease combination therapy: Ἀρεταίου Καππαδόκου Τὰ Σωζόμενα Ἀρεταῖος (Καππαδόκης), 1856 Garrison ranks Aretaeus second only to Hippocrates in his descriptions of disease. |
crohn's disease combination therapy: Integrative Gastroenterology Gerard E. Mullin, Marvin Singh, Alyssa Parian, 2019-09-27 Digestive complaints have become increasingly common. Recent statistics show that gastrointestinal complaints account for nearly a third of all visits to primary care doctors and that nearly one in two Americans suffer from digestive disease. Millions more suffer from conditions such as migraine headaches, arthritis, mood disorders, chronic fatigue, asthma, allergies, and menstrual dysfunction, which are all related to a disorder in digestive health. Despite the evidence in support of integrative approaches to treatment and prevention of digestive symptoms, these approaches are largely overlooked in treating gastrointestinal disorders. Rather, treatment plans tend to be exclusively pharmacologically based and have appreciable toxicity. Integrative Gastroenterology, Second edition, is a comprehensive guide to helping health care practitioners understand and appreciate how to manage patients with gastrointestinal conditions integrating conventional and complimentary approaches. This text reviews the latest advances in science and research with regards to the gut microbiome, physiology, and interconnections between the gut and other organ systems. Coverage includes a diverse range of treatment methods, such as probiotics, meditation, massage, yoga, supplements, special diets, energy medicine, homeopathy, and acupuncture, as well as a special section devoted to mind-body medicine in digestive health and disease. In discussing unconventional treatments, the authors address many of the controversies that surround the remedies. |
crohn's disease combination therapy: Gutbliss Robynne Chutkan M.D., 2014-10-07 A renowned physician shares her complete 10-day digestive tune-up for women, with important revelations about good gastrointestinal health. Many so-called cures for women’s bloating and indigestion, from juice cleanses to specialty diets, are based on junk science. For women seeking true relief from that overall feeling of discomfort in any size jeans, Dr. Robynne Chutkan has the perfect plan for feeling light, tight, and bright in ten days. Gutbliss offers: A primer on the real reasons for gastrointestinal distress, and why it’s much more common in women A look at the debilitating side effects of supposedly healthy habits—from Greek yogurt to bloat-inducing aspirin An expert analysis of symptoms that could indicate a serious underlying condition An indispensable checklist to pinpoint the exact cause of your bloating Just a few small changes in diet, lifestyle, and exercise can make a huge difference in a woman’s digestive health, but the changes have to be the right ones. Going beyond the basics of top sellers such as Wheat Belly, Dr. Chutkan’s Gutbliss empowers women to take control of their gastrointestinal wellness. |
crohn's disease combination therapy: Interleukin-6-type Cytokines Andrzej Mackiewicz, A. Koj, Pravinkumar B. Sehgal, 1995 This volume discusses the role of interleukin-6-type cytokines in haematopoietic cell proliferation, neuronal differentiation and acute phase response to inflammation. New data is presented concerning the structure and function of interleukin-6, the leukemia inhibitory factor, interleukin-11, oncostatin M and the ciliary neurotrophic factor. Also discussed is cytokine receptor function, common signal transduction mechanisms, the molecular basis of cytokine-mediated alterations in gene expression, and regulation of cell proliferation. Pre-clinical and clinical studies with these cytokines are evaluated. |
crohn's disease combination therapy: Nutrition Guide for Clinicians Neal D. Barnard, Rick Weissinger, MS, Brent J. Jaster, MD, 2009 Designed by medical professionals, this manual is a comprehensive, portable medical reference that covers nearly one hundred diseases and conditions, including risk factors, diagnoses, and typical treatments. Most importantly, it provides the latest evidence-based information on nutrition's role in prevention and treatment. |
crohn's disease combination therapy: Breastfeeding and Medication Wendy Jones, 2018-05-11 Sadly, women often feel they have no alternative but to give up breastfeeding, having been prescribed or purchased medication. In many cases, however, this is unnecessary. This book outlines the evidence base for the use of medication during breastfeeding. Breastfeeding and Medication presents a comprehensive A to Z guide to the most frequently prescribed drugs and their safety for breastfeeding mothers. Evaluating the evidence for interventions and using a simple format for quickly identifying medications that are safe or unsafe to use, it also highlights those drugs where there is inconclusive evidence. Additional contextual information makes this the most complete text for those practitioners who support and treat breastfeeding women. It: provides an overview of the anatomy and physiology of the breast together with hormonal influences to better understand how complications, such as mastitis, arise and inform the approach to their treatment; includes a section on conditions that affect women specifically when they are lactating where prescription of medication may be necessary; discusses the importance of breastfeeding and its advantages, as well as its disadvantages; and explores how to support breastfeeding mothers, and presents a counselling model approach. This new edition contains information on more drugs and a chapter on the management of some chronic conditions which may affect breastfeeding mothers. In most cases there are options to support the mother’s optimal care whilst allowing her to continue to breastfeed her baby as long as she wishes. This is a topic which raises many questions on social media, which informed the choice of conditions to consider. This is an invaluable reference for all health practitioners and volunteers who work with, support and treat breastfeeding women, including lactation consultants, breastfeeding support workers, health visitors, GPs, practice nurses, pharmacists and midwives. |
crohn's disease combination therapy: Colitis-Associated Cancer Masato Kusunoki, 2015-10-01 As the number of patients with colitis-associated cancer (CAC) is on the increase, the purpose of this book is to review the latest topics concerning management of the disease. In recent years, the diagnostic power of endoscopy and molecular pathology has also grown tremendously, as a result of which they now have a far greater influence on the treatment of CAC. At the moment, appropriate monitoring programs for ulcerative colitis and Crohn’s disease remain uncertain. At the same time, the latest findings on DNA methylation and microRNAs hold the promise of making revolutionary changes in these areas. Moreover, recent drug advances in the treatment of inflammatory bowel diseases have changed surgical indications. On the other hand, the indication of mucosectomy on colorectal cancer in ulcerative colitis and prophylactic abdominoperineal resection for Crohn’s disease remain controversial. This book provides the latest information on the remaining issues of CAC from the point of view of expert surgeons. |
crohn's disease combination therapy: Personalizing Treatment In IBD: Hype or Reality In 2020? Fernando Gomollón, Edouard Louis, 2021-07-05 |
crohn's disease combination therapy: Moderate to Severe Psoriasis John Koo, Jashin Wu, Alice Gottlieb, Ethan Levin, Argentina Leon, 2014-03-18 Written by experts in the dermatology field, this new fourth edition of Moderate-to-Severe Psoriasis discusses the current use of biologics and other pharmacologic and phototherapy treatments for moderate-to-severe psoriasis. Illustrated with high quality color figures, this standalone text emphasizes safe and effective treatments for the psoriasis |
crohn's disease combination therapy: Evidence-Based Medicine Toolkit Carl Heneghan, Douglas Badenoch, 2013-05-06 This bestselling pocket guide to the skills of evidence-basedmedicine succeeds in demystifying the terminology and processes ina handy and easy-to-follow format, all within the space of 100pages. With an improved layout, this second edition ofEvidence-based Medicine Toolkit offers more up-to-dateguidance as well as new sections on important areas ofresearch. New features of this second edition include: A box for each major database showing how to search theevidence, and highlighting the differences between them Flow charts for different study types New critical appraisal sections on qualitative research andeconomic evaluation Expanded list of EBM resources on the net. With these added features to make the job easier, the newToolkit is now an even better companion for all health careprofessionals using evidence-based methodology in their researchand practice. |
crohn's disease combination therapy: HIV Infection in Children and Adolescents Raziya Bobat, 2020-02-27 This book serves as a reference work on pediatric HIV infection and covers the full bandwidth of topics from an introduction to pathogenesis and epidemiology, over the transmission of the HI virus, to clinical manifestations, treatment, and prevention strategies. Diseases and disorders occurring in HIV infected persons are discussed in detail. The book covers special populations, such as neonates born to an HIV positive mother and adolescents and examines the specific ways of managing HIV disease in these patient groups. This is the first book to cover palliative care as well as ethical, legal and social issues of HIV infection. |
crohn's disease combination therapy: Surgery for Crohn's Disease Stephen M. Kavic, 2015 Crohn's disease is a chronic illness that afflicts millions of patients worldwide. Despite its increasing recognition as a medical specialty within gastroenterology, there has been little attention devoted to Crohn's from a surgical perspective. This volume fills that void and acts as the first catalogue to address the surgical management of Crohn's disease. The goal of this work was to provide surgeons with the latest medical and surgical information to manage patients with Crohn's disease effectively.In this book, contributions from both gastroenterologists describe the history, diagnosis, nutrition, medical management, and surveillance of Crohn's disease. Chapters from general and colorectal surgeons detail common clinical techniques, minimally invasive surgical approach and management of perianal disease. In addition, surgical complications specific to Crohn's disease are also reviewed.This book provides all of the essential information needed in the surgical management of Crohn's disease in one simple volume. It aims to be a useful resource for practicing surgeons and surgical residents as well as gastroenterologists. The authors wish readers to understand the complex decision making and sophisticated surgical techniques that these patients often demand. |
crohn's disease combination therapy: Interventional Inflammatory Bowel Disease: Endoscopic Management and Treatment of Complications Bo Shen, 2018-01-16 Interventional Inflammatory Bowel Diseases: Endoscopic Management and Treatment of Complications covers the preparation, principle, techniques, and damage control of complications in endoscopic therapy, providing the ultimate guidance in endoscopic management of IBD. With contributions from a panel of international leading experts in the field, perspectives are included from GI pathologists, GI radiologists, gastroenterologists, advanced endoscopists, IBD specialists and colorectal surgeons. Recommendations from experts are also included within each chapter. By bridging medical and surgical treatment modalities for IBD, this is the perfect reference for GI researchers, medical students, therapeutic GI endoscopists, IBD specialists, surgeons and advanced health care providers. - Incorporates state-of-the-art of research in the area of therapeutic endoscopy in Crohn's Disease and Ulcerative Colitis - Makes the connection between the understanding of the complex nature and disease course of IBD with corresponding advanced endoscopic procedures - Explores endoscopic treatment as the missing link between medical and surgical treatment for complex Crohn's Disease and Ulcerative Colitis - Contains access to videos demonstrating important procedural concepts |
crohn's disease combination therapy: Radiation Therapy for Skin Cancer Armand B Cognetta, William M. Mendenhall, 2013-06-13 Photon Radiation Therapy for Skin Malignancies is a vital resource for dermatologists interested in radiation therapy, including the physics and biology behind treatment of skin cancers, as well as useful and pragmatic formulas and algorithms for evaluating and treating them. Dermatology has always been a field that overlaps multiple medical specialties and this book is no exception, with its focus on both dermatologists and radiation oncologists. It is estimated that between 2010 and 2020, the demand for radiation therapy will exceed the number of radiation oncologists practicing in the U.S. tenfold, which could profoundly affect the ability to provide patients with sufficient access to treatment. Photon Radiation Therapy for Skin Malignancies enhances the knowledge of dermatologists and radiation oncologists and presents them with the most up-to-date information regarding detection, delineation and depth determination of skin cancers, and appropriate biopsy techniques. In addition, the book also addresses radiation therapy of the skin and the skin’s reactions to radiation therapy. |
crohn's disease combination therapy: Prognostic Factors in Cancer Paul Hermanek, 1995 |
crohn's disease combination therapy: Living with Crohn's & Colitis Jessica Black, N.D., Dede Cummings, 2010-06-29 A wellness plan for those with inflammatory bowel diseases like Crohn’s and ulcerative colitis—with expert guidance on creating a gut-healthy diet, finding the right treatments for you, and much more Approximately 1.5 million people in the United States alone are afflicted with inflammatory bowel disease (IBD), a category of illnesses that includes Crohn’s disease and ulcerative colitis, and that number is steadily growing. Although there is not yet a cure for Crohn’s or ulcerative colitis, patients can help reduce their symptoms and improve their overall wellbeing by following a comprehensive wellness plan such as those outlined in Living with Crohn’s & Colitis. Living with Crohn’s & Colitis offers patient-focused, expert guidance on everything from the latest medical treatments, how to cope with a diagnosis, and tips for balancing diet with a busy lifestyle so you can form a personalized wellness plan. Also included: • Easy to understand information on the role of inflammation and the immune system on gut health • Traditional and alternative treatment options for a broad, full-body approach to wellness • A three-month wellness plan adjustable to each individual’s health needs • Over 25 delicious recipes designed for those with IBD Learning to live with the myriad aspects of Crohn’s and ulcerative colitis treatment, including dietary restrictions and medications, can seem overwhelming. Written by a naturopathic doctor and a Crohn’s patient, Living with Crohn’s & Colitis is a thoughtful, balanced resource to help you on your journey to wellness. |
crohn's disease combination therapy: Kirsner's Inflammatory Bowel Diseases Joseph B. Kirsner, 2004 This comprehensive New Edition describes all of the latest scientific and clinical advances in the field of inflammatory bowel disease (IBD). A new editorial team-joined by a superb group of international authorities-examine every aspect of IBD-including etiology and pathogenesis, diagnosis and evaluation, medical and surgical therapy, and more. A wealth of expanded coverage, additional international contributors, extensive updating throughout, and numerous diagnostic and therapeutic algorithms make this an essential resource. Emphasizes evidence-based medicine in the section on medical therapy. Features a detailed description of inflammatory and immunologic pathways, allowing the reader to fully understand the contributing influences to the inflammation of IBD. Presents separate chapters on molecular genetics and clinical genetics for more in-depth coverage of each aspect of inflammatory bowel disease genetics. Provides a comprehensive review of IBD through abundant, high-quality endoscopic, radiographic, and histologic photographs-placing the various diagnostic modalities in perspective. Offers extensive coverage of postoperative recurrence of Crohn's disease · pouchitis · microscopic colitis · perianal disease · and osteoporosis. Includes up-to-the-minute guidance (including many 2003 references). Features a new editorial team, joined by numerous new contributors who provide fresh, global perspectives. Includes nine new chapters. Offers expanded coverage throughout, and through revisions of all pre-existing chapters. With over 75 additional contributing experts. |
crohn's disease combination therapy: Advanced Therapy of Inflammatory Bowel Disease Theodore M. Bayless, Stephen B. Hanauer, 2001 Advanced Therapy of Inflammatory Bowel Disease - Second Edition The main emphasis of this new edition is on diagnosis, therapy and patient management, along with disease activity measures, IBD databases, and the use of diagnostic tests in clinical decision making. Each chapter consists of recommendations from an expert in the ...... |
crohn's disease combination therapy: Advanced Therapy of Inflammatory Bowel Disease, Volume 2 Theodore M. Bayless, Stephen B. Hanauer, 2014-05-14 Now published in two volumes to accommodate new chapters on the many advances in understanding and treatment options, this set of volumes represents the definitive reference on inflammatory bowel disease, a spectrum of diseases that is receiving increasing attention as our understanding of the etiological factors increases and diagnostic tools are refined. Basic research accelerated at the beginning of this decade and is now yielding new, more targeted treatments than were available just a few years ago. Volume 1 is on IBD and Ulcerative Colitis, and Volume 2 is on IBD and Crohn's Disease. All areas that were covered in the 2nd edition have been expanded and updated. New sections include the rapidly expanding knowledge of genetics and the role of the intestinal flora and environmental factors in etiology and pathogenesis. Among the 168 chapters, there are 20 on biologic therapies and 30 on surgical management. The consultant/authors clearly state their approach to important issues, such as the duration of immunomodulator and of anti-TNF-a use and the options for managing isolated low-grade dysplasia. A strong focus on the individual patient is woven throughout both volumes, including the benefits and risks of potentially life-altering therapies and surgeries. Entire sections detail concerns about the well-being of each person. This book provides information for health professionals who help both pediatric and adult patients navigate through the lifelong shadow of a chronic, probably genetically determined ordeal. |
crohn's disease combination therapy: Treatment of Inflammatory Bowel Disease with Biologics Adam S. Cheifetz, Joseph D. Feuerstein, 2017-11-09 This book is a concise yet comprehensive overview of the use of biologics for the treatment of Crohn’s disease and ulcerative colitis. The volume details how best to utilize these medications in order to optimize their efficacy and safety, as well as how to understand, recognize, and treat complications that may arise from using biologics to treat IBD. The text also focuses on new data, novel biologics, and biosimilars of this rapidly expanding field. Written by experts in the field, Treatment of Inflammatory Bowel Disease with Biologics is a valuable resource for gastroenterologists, allied health professionals, fellows, and trainees who treat patients with inflammatory bowel disease. |
crohn's disease combination therapy: Non-neoplastic Pathology of the Gastrointestinal Tract Roger Feakins, 2019 Prior to the development of the first fibre-optic endoscopes in the 1960's, gastroenterology, in common with other traditional medical specialties, relied on biochemical and radiological techniques in order to investigate the gastrointestinal tract. Histological confirmation of a disease process usually required the presence of a surgeon, was invasive, and carried inherent risks. Because of a rapid improvement in technology, we are now able to sample the entire gastrointestinal tract from the mouth and anus through to the ileal / jejunal junction-- |
crohn's disease combination therapy: Crohn's Disease: New Insights for the Healthcare Professional: 2013 Edition , 2013-07-22 Crohn’s Disease: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Crohn’s Disease: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Crohn’s Disease: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
Crohn's disease - Symptoms and causes - Mayo Clinic
Oct 29, 2024 · Crohn's disease is an inflammatory bowel disease that causes chronic inflammation of the GI tract, which extends from your stomach all the way down to your anus. …
Crohn's disease - Wikipedia
Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any segment of the gastrointestinal tract. [3] Symptoms often include abdominal pain, diarrhea, fever, abdominal …
Crohn’s Disease: What It Is, Symptoms, Causes & Treatment
Dec 4, 2023 · Crohn’s disease is a type of inflammatory bowel disease (IBD) that causes your digestive tract to become swollen and irritated. If you have Crohn’s, you might experience …
Crohn's disease: Understanding symptoms, diagnosis and ...
6 days ago · Risk factors for Crohn’s disease. You can develop Crohn’s disease at any age, but it’s most often diagnosed between the ages of 20 and 29. Several factors increase your risk, …
Crohn's Disease Basics | IBD | CDC - Centers for Disease ...
Jun 21, 2024 · Crohn’s disease is a type of inflammatory bowel disease (IBD) that can affect any part of the digestive tract, from the mouth to the anus. It inflames areas of the intestine walls, …
Crohn Disease - StatPearls - NCBI Bookshelf
Sep 15, 2020 · Crohn disease is an immunologically mediated inflammatory gastrointestinal condition, with pathology involving the entire thickness of the bowel wall. Crohn disease is a …
Symptoms & Causes of Crohn’s Disease - NIDDK
Learn about the symptoms of Crohn’s disease—which include diarrhea, cramping, and pain in your abdomen, and weight loss—and possible causes of the disease.
Crohn's disease - Symptoms and causes - Mayo Clinic
Oct 29, 2024 · Crohn's disease is an inflammatory bowel disease that causes chronic inflammation of the GI tract, which extends from your stomach all the way …
Crohn's disease - Wikipedia
Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any segment of the gastrointestinal tract. [3] Symptoms often include abdominal pain, …
Crohn’s Disease: What It Is, Symptoms, Causes & Treatment
Dec 4, 2023 · Crohn’s disease is a type of inflammatory bowel disease (IBD) that causes your digestive tract to become swollen and irritated. If you have Crohn’s, you might …
Crohn's disease: Understanding symptoms, diagnosis and ...
6 days ago · Risk factors for Crohn’s disease. You can develop Crohn’s disease at any age, but it’s most often diagnosed between the ages of 20 and 29. Several factors increase …
Crohn's Disease Basics | IBD | CDC - Centers for Disease ...
Jun 21, 2024 · Crohn’s disease is a type of inflammatory bowel disease (IBD) that can affect any part of the digestive tract, from the mouth to the anus. It inflames areas of the …
Crohn Disease - StatPearls - NCBI Bookshelf
Sep 15, 2020 · Crohn disease is an immunologically mediated inflammatory gastrointestinal condition, with pathology involving the entire thickness of the bowel …
Symptoms & Causes of Crohn’s Disease - NIDDK
Learn about the symptoms of Crohn’s disease—which include diarrhea, cramping, and pain in your abdomen, and weight loss—and possible causes of the disease.