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| current opinion in structural biology: Liposomes, Lipid Bilayers and Model Membranes Georg Pabst, Norbert Kučerka, Mu-Ping Nieh, John Katsaras, 2014-03-04 As a result of their unique physical properties, biological membrane mimetics, such as liposomes, are used in a broad range of scientific and technological applications. Liposomes, Lipid Bilayers and Model Membranes: From Basic Research to Application describes state-of-the-art research and future directions in the field of membranes, which has evolved from basic studies of the physicochemical properties of amphiphiles to their application in industry and medicine. Written by leading researchers in their fields, this book describes basic and applied research, and serves as a useful reference for both the novice and the expert. Part one covers a range of basic research topics, from theory and computational simulations to some of the most up-to-date experimental research. Topics discussed include soft matter physics of membranes, nonlamellar phases, extraction of molecules by amphiphiles, lipid models for membrane rafts, membrane dynamics, nanodiscs, microemulsions, active membranes, as well as interactions of bilayers with drugs or DNA to treat disease or for gene transfer, respectively. Part two of the book focuses on technological applications of amphiphiles, such as liposome-based nanoparticles for drug delivery, formulation of liposomes for prolonged in vivo circulation and functionalization for medical purposes, novel drug delivery systems for increased drug loading, and the use of tethered membranes for bio-sensing applications. Chapters also describe the use of liposomes in textile dyeing and how lipidic nanoparticles are used by the food industry. |
| current opinion in structural biology: Molecular To Global Photosynthesis Mary D Archer, James Barber, 2004-05-10 Green plants and photosynthetic organisms are the Earth's natural photoconverters of solar energy. In future, biomass and bioenergy will become increasingly significant energy sources, making a contribution both to carbon dioxide abatement and to the security, diversity and sustainability of global energy supplies. In this book, experts provide a series of authoritative chapters on the intricate mechanisms of photosynthesis and the potential for using and improving photosynthetic organisms, plants and trees to sequester carbon dioxide and to provide fuel and useful chemicals for the benefit of man./a |
| current opinion in structural biology: Protein Structure Prediction Mohammed Zaki, Chris Bystroff, 2007-09-12 This book covers elements of both the data-driven comparative modeling approach to structure prediction and also recent attempts to simulate folding using explicit or simplified models. Despite the unsolved mystery of how a protein folds, advances are being made in predicting the interactions of proteins with other molecules. Also rapidly advancing are the methods for solving the inverse folding problem, the problem of finding a sequence to fit a structure. This book focuses on the various computational methods for prediction, their successes and their limitations, from the perspective of their most well known practitioners. |
| current opinion in structural biology: Nuclear Magnetic Resonance G A Webb, 2007-10-31 As a spectroscopic method, Nuclear Magnetic Resonance (NMR) has seen spectacular growth over the past two decades, both as a technique and in its applications. Today the applications of NMR span a wide range of scientific disciplines, from physics to biology to medicine. Each volume of Nuclear Magnetic Resonance comprises a combination of annual and biennial reports which together provide comprehensive of the literature on this topic. This Specialist Periodical Report reflects the growing volume of published work involving NMR techniques and applications, in particular NMR of natural macromolecules which is covered in two reports: NMR of Proteins and Acids and NMR of Carbohydrates, Lipids and Membranes. For those wanting to become rapidly acquainted with specific areas of NMR, this title provides unrivalled scope of coverage. Seasoned practitioners of NMR will find this an in valuable source of current methods and applications. Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant subject areas, the series creates a unique service for the active research chemist, with regular, in-depth accounts of progress in particular fields of chemistry. Subject coverage within different volumes of a given title is similar and publication is on an annual or biennial basis. |
| current opinion in structural biology: Biological Inorganic Chemistry Robert R. Crichton, 2012-02-02 The study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology constitutes the subject called Biological Inorganic Chemistry. This text, written by a biochemist, presents an introduction to this field. |
| current opinion in structural biology: Nucleic Acids: Advances in Research and Application: 2011 Edition , 2012-01-09 Nucleic Acids: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Nucleic Acids, Nucleotides, and Nucleosides. The editors have built Nucleic Acids: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Nucleic Acids, Nucleotides, and Nucleosides in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Nucleic Acids: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| current opinion in structural biology: Protein Engineering Handbook Stefan Lutz, Uwe Theo Bornscheuer, 2012-07-31 Unparalleled in size and scope, this new major reference integrates academic and industrial knowledge into a single resource, allowing for a unique overview of the entire field. Adopting a systematic and practice-oriented approach, and including a wide range of technical and methodological information, this highly accessible handbook is an invaluable 'toolbox' for any bioengineer. In two massive volumes, it covers the full spectrum of current concepts, methods and application areas. |
| current opinion in structural biology: List of Journals Indexed in Index Medicus National Library of Medicine (U.S.), 1996 Issues for 1977-1979 include also Special List journals being indexed in cooperation with other institutions. Citations from these journals appear in other MEDLARS bibliographies and in MEDLING, but not in Index medicus. |
| current opinion in structural biology: Cumulated Index Medicus , 1989 |
| current opinion in structural biology: Cryo-Electron Microscopy in Structural Biology Krishnarao Appasani, 2024-10-17 Cryo-electron microscopy, in combination with tomography, has emerged as a new technology for visualizing molecular structures at a resolution beyond even 1 Å. Using this technology has revealed the native molecular details of viruses, membranes, enzymes, ribosomes, and cells. This comprehensive volume brings together authoritative overviews of these methods from structural and biological perspectives. It is a must-have for researchers and graduate students, as well as those working in industry, primarily in the areas of biophysics, structural biology, crystallography, and genomics. Key Features • Focuses on the applications of cryo-EM to structural biology • Documents the importance of cryo-EM/ET approaches in studying the structural determinants of cellular organelle and membrane protein biochemistry • Reviews the applications of high-resolution structures of viruses • Emphasizes structural insights of nuclear and gene machineries • Includes a section focused entirely on the applications of cryo-EM/ET in drug discovery and therapeutic development |
| current opinion in structural biology: Proteins: Advances in Research and Application: 2011 Edition , 2012-01-09 Proteins: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Amino Acids, Peptides, and Proteins. The editors have built Proteins: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Amino Acids, Peptides, and Proteins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Proteins: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| current opinion in structural biology: Multi-Agent-Based Simulations Applied to Biological and Environmental Systems Adamatti, Diana Francisca, 2016-12-12 The discovery and development of new computational methods have expanded the capabilities and uses of simulations. With agent-based models, the applications of computer simulations are significantly enhanced. Multi-Agent-Based Simulations Applied to Biological and Environmental Systems is a pivotal reference source for the latest research on the implementation of autonomous agents in computer simulation paradigms. Featuring extensive coverage on relevant applications, such as biodiversity conservation, pollution reduction, and environmental risk assessment, this publication is an ideal source for researchers, academics, engineers, practitioners, and professionals seeking material on various issues surrounding the use of agent-based simulations. |
| current opinion in structural biology: Handbook of Ion Channels Jie Zheng, Matthew C. Trudeau, 2015-02-25 The New Benchmark for Understanding the Latest Developments of Ion ChannelsIon channels control the electrical properties of neurons and cardiac cells, mediate the detection and response to sensory stimuli, and regulate the response to physical stimuli. They can often interact with the cellular environment due to their location at the surface of ce |
| current opinion in structural biology: Scattering Methods in Structural Biology Part B , 2023-01-12 Scattering Methods in Structural Biology, Part B, Volume 676 in the Methods in Enzymology serial, highlights advances in the field, presenting chapters on Quality controls, Refining biomolecular structures and ensembles by SAXS-driven molecular dynamics simulations, Data analysis and modelling of small-angle scattering data with contrast variation, Observing protein degradation in solution by the PAN-20S proteasome complex: state-of-the-art and future perspectives of TR-SANS as a complementary tool to NMR, crystallography and Cryo-EM, Extracting structural insights from chemically-specific soft X-ray scattering, Reconstruction of 3D density of biological macromolecules from solution scattering, ATSAS- present state and new developments in computational methods, and much more. Additional chapters cover Modeling Structure and Dynamics of Protein Complexes with SAXS Profiles (FoXSDock and MultiFoXS), Validation of macromolecular flexibility in solution by SAXS, Combining NMR, SAXS and SANS to characterize the structure and dynamics of protein complexes, Application of Molecular Simulation Methods to Analyze SAS Data, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology serial - Updated release includes the latest information on Small Angle Scattering Methods for Structural Interpretation |
| current opinion in structural biology: Comprehensive Nanoscience and Technology , 2010-10-29 From the Introduction: Nanotechnology and its underpinning sciences are progressing with unprecedented rapidity. With technical advances in a variety of nanoscale fabrication and manipulation technologies, the whole topical area is maturing into a vibrant field that is generating new scientific research and a burgeoning range of commercial applications, with an annual market already at the trillion dollar threshold. The means of fabricating and controlling matter on the nanoscale afford striking and unprecedented opportunities to exploit a variety of exotic phenomena such as quantum, nanophotonic and nanoelectromechanical effects. Moreover, researchers are elucidating new perspectives on the electronic and optical properties of matter because of the way that nanoscale materials bridge the disparate theories describing molecules and bulk matter. Surface phenomena also gain a greatly increased significance; even the well-known link between chemical reactivity and surface-to-volume ratio becomes a major determinant of physical properties, when it operates over nanoscale dimensions. Against this background, this comprehensive work is designed to address the need for a dynamic, authoritative and readily accessible source of information, capturing the full breadth of the subject. Its six volumes, covering a broad spectrum of disciplines including material sciences, chemistry, physics and life sciences, have been written and edited by an outstanding team of international experts. Addressing an extensive, cross-disciplinary audience, each chapter aims to cover key developments in a scholarly, readable and critical style, providing an indispensible first point of entry to the literature for scientists and technologists from interdisciplinary fields. The work focuses on the major classes of nanomaterials in terms of their synthesis, structure and applications, reviewing nanomaterials and their respective technologies in well-structured and comprehensive articles with extensive cross-references. It has been a constant surprise and delight to have found, amongst the rapidly escalating number who work in nanoscience and technology, so many highly esteemed authors willing to contribute. Sharing our anticipation of a major addition to the literature, they have also captured the excitement of the field itself in each carefully crafted chapter. Along with our painstaking and meticulous volume editors, full credit for the success of this enterprise must go to these individuals, together with our thanks for (largely) adhering to the given deadlines. Lastly, we record our sincere thanks and appreciation for the skills and professionalism of the numerous Elsevier staff who have been involved in this project, notably Fiona Geraghty, Megan Palmer and Greg Harris, and especially Donna De Weerd-Wilson who has steered it through from its inception. We have greatly enjoyed working with them all, as we have with each other. |
| current opinion in structural biology: Advances in Protein Chemistry and Structural Biology , 2024-01-11 Advances in Protein Chemistry and Structural Biology, Volume 138 covers reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design. Chapters in this release include Proteomic Applications in Identifying Protein-Protein Interactions, Understanding functions of eEF1 translation elongation factors beyond translation. A proteomic approach, Proteomics provides insights into theranostic potential of extracellular vesicles, Towards a shareable functional analysis of the structural proteome, Functional unfoldomics, In-silico Network Pharmacology Study on Glycyrrhiza glabra: Analyzing the Immune-Boosting phytochemical properties of Siddha Medicinal Plant against COVID-19, and more.Other chapters cover In silico Network Pharmacology Analysis and Molecular Docking Validation of Swasa Kudori for Screening Druggable Phytoconstituents of Asthma, Proteomics and Genomics Insights on Malignant Osteosarcoma, Application of functional proteomics in understanding RNA Virus-Mediated Infection, Biofilm proteome of Staphylococcus aureus: implications for therapeutic interventions to biofilm-associated infections, A computational pipeline elucidating functions of conserved hypothetical Trypanosoma cruzi proteins based on public proteomic data, Functional Proteomics based on Protein Microarray Technology for Biomedical Research, and an Analysis of endoglucanases production using proteomics and metatranscriptomics. - Includes new information about Protein Aggregation - Presents chapters by a wide range of leading experts - Cover new, cutting-edge information that will serve as an essential addition to any bookshelf or laboratory |
| current opinion in structural biology: Machine Learning in Bioinformatics Yanqing Zhang, Jagath C. Rajapakse, 2009-02-23 An introduction to machine learning methods and their applications to problems in bioinformatics Machine learning techniques are increasingly being used to address problems in computational biology and bioinformatics. Novel computational techniques to analyze high throughput data in the form of sequences, gene and protein expressions, pathways, and images are becoming vital for understanding diseases and future drug discovery. Machine learning techniques such as Markov models, support vector machines, neural networks, and graphical models have been successful in analyzing life science data because of their capabilities in handling randomness and uncertainty of data noise and in generalization. From an internationally recognized panel of prominent researchers in the field, Machine Learning in Bioinformatics compiles recent approaches in machine learning methods and their applications in addressing contemporary problems in bioinformatics. Coverage includes: feature selection for genomic and proteomic data mining; comparing variable selection methods in gene selection and classification of microarray data; fuzzy gene mining; sequence-based prediction of residue-level properties in proteins; probabilistic methods for long-range features in biosequences; and much more. Machine Learning in Bioinformatics is an indispensable resource for computer scientists, engineers, biologists, mathematicians, researchers, clinicians, physicians, and medical informaticists. It is also a valuable reference text for computer science, engineering, and biology courses at the upper undergraduate and graduate levels. |
| current opinion in structural biology: Fundamentals of Porphyrin Chemistry Penelope J. Brothers, Mathias O. Senge, 2022-06-15 FUNDAMENTALS OF PORPHYRIN CHEMISTRY An indispensable and concise overview of the chemistry of porphyrins and related molecules In Fundamentals of Porphyrin Chemistry: A 21st Century Approach, a team of distinguished researchers delivers a compact and accessible introduction to the broad field of porphyrin chemistry. It discusses the basics of porphyrin synthesis and structure, as well as that of related molecules, and the current and future roles that porphyrins play in chemical transformations, materials design and synthesis, energy capture and transduction, human health, and the environment. This edited volume is a self-contained tutorial on concepts of critical importance to porphyrin chemistry and serves as the foundation for discussions about the applications of porphyrin-related compounds found in the second volume. This book contains: A thorough introduction to porphyrins, including their structure, nomenclature, naturally occurring porphyrins, synthetic porphyrins, and common families of porphyrin-related compounds Comprehensive explorations of chemical porphyrin synthesis, including how to synthesize porphyrins from simple, symmetric, and advanced ABCD-substituted porphyrins Practical discussions of the physical characteristics of porphyrins, including their structural features, electronic structure, spectroscopy, magnetism, electrochemistry, and electron transfer processes Perfect for experienced academic researchers in the field of porphyrin chemistry seeking a quick reference, Fundamentals of Porphyrin Chemistry: A 21st Century Approach is also an indispensable resource for researchers new to the field who need an overview directing them to literature in more focused areas. |
| current opinion in structural biology: Proteins Gary Walsh, 2014-03-13 Proteins Biochemistry and Biotechnology 2e is a definitive source of information for all those interested in protein science, and particularly the commercial production and isolation of specific proteins, and their subsequent utilization for applied purposes in industry and medicine. Fully updated throughout with new or fundamentally revised sections on proteomics as, bioinformatics, protein glycosylation and engineering, well as sections detailing advances in upstream processing and newer protein applications such as enzyme-based biofuel production this new edition has an increased focus on biochemistry to ensure the balance between biochemisty and biotechnology, enhanced with numerous case studies. This second edition is an invaluable text for undergraduates of biochemistry and biotechnology but will also be relevant to students of microbiology, molecular biology, bioinformatics and any branch of the biomedical sciences who require a broad overview of the various medical, diagnostic and industrial uses of proteins. • Provides a comprehensive overview of all aspects of protein biochemisty and protein biotechnology • Includes numerous case studies • Increased focus on protein biochemistry to ensure balance between biochemisty and biotechnology • Includes new section focusing on proteomics as well as sections detailing protein function and enzyme-based biofuel production With the potential of a standard reference source on the topic, any molecular biotechnologist will profit greatly from having this excellent book. (Engineering in Life Sciences, 2004; Vol 5; No. 5) “Few texts would be considered competitors, and none compare favorably. (Biochemistry and Molecular Education, July/August 2002) ...The book is well written, making it informative and easy to read... (The Biochemist, June 2002) |
| current opinion in structural biology: Molecular Biology Nancy Lynn Craig, Orna Cohen-Fix, Gisela Storz, 2014 Molecular Biology: Principles of Genome Function offers a fresh, distinctive approach to the teaching of molecular biology. It is an approach that reflects the challenge of teaching a subject that is in many ways unrecognizable from the molecular biology of the 20th century - a discipline in which our understanding has advanced immeasurably, but about which many intriguing questions remain to be answered. It is written with severalguiding themes in mind: - A focus on key principles provides a robust conceptual framework on which students can build a solid understanding of the discipline; - An emphasis on thecommonalities that exist between the three kingdoms of life, and the discussion of differences between the three kingdoms where such differences offer instructive insights into molecular processes and components, gives students an accurate depiction of our current understanding of the conserved nature of molecular biology, and the differences that underpin biological diversity; - An integrated approach demonstrates how certain molecular phenomena have diverse impacts on genomefunction by presenting them as themes that recur throughout the book, rather than as artificially separated topics At heart, molecular biology is an experimental science, and a centralelement to the understanding of molecular biology is an appreciation of the approaches taken to yield the information from which concepts and principles are deduced. Yet there is also the challenge of introducing the experimental evidence in a way that students can readily comprehend. Molecular Biology responds to this challenge with Experimental Approach panels, which branch off from the text in a clearly-signposted way. These panels describe pieces ofresearch that have been undertaken, and which have been particularly valuable in elucidating difference aspects of molecular biology. Each panel is carefully cross-referenced to the discussion of key molecular biologytools and techniques, which are presented in a dedicated chapter at the end of the book. Beyond this, Molecular Biology further enriches the learning experience with full-colour, custom-drawn artwork; end-of-chapter questions and summaries; relevant suggested further readings grouped by topic; and an extensive glossary of key terms. Among the students being taught today are the molecular biologists of tomorrow; these individuals will be ina position to ask fascinating questions about fields whose complexity and sophistication become more apparent with each year that passes. Molecular Biology: Principles of Genome Function is the perfectintroduction to this challenging, dynamic, but ultimately fascinating discipline. |
| current opinion in structural biology: Molecular Simulation Studies in Material and Biological Sciences Kholmirzo Kholmurodov, 2007 Book & CD. Computer molecular simulations of complex multi-particle systems play a fascinating role in fundamental physics, biochemical and life sciences. Having an increasingly significant impact on many applied industries, especially in modern biophysical and nanotechnological areas, molecular simulation provides a set of tools for predicting many functional properties of molecular systems. The chemical, pharmaceutical, materials and related industries -- all share the computer molecular simulation methods. The molecular simulation studies cover different fields of either biological processes -- protein folding and electron densities of DNA and proteins, or thin film formations and surface-cluster phenomena in nanoelectronics, synthetic copolymers and biopolymer design in biochemistry, so on. Practically all of the world's present supercomputers and many specially developed high performance computing clusters over the world are performing molecular simulations or are aimed on these needs. This book presents leading international research in this dynamic field. |
| current opinion in structural biology: Chemical Processes in Marine Environments Antonio Gianguzza, Ezio Pelizzetti, Silvio Sammartano, 2013-06-29 This book discusses recent developments in the study of chemical processes and equilibria in the marine environment and in the air/water and water/sediment interfaces. The chemical cycle of carbon as well as the effect of organic substances on the speciation and distribution of inorganic and organometallic substances are extensively discussed. Much of the recent progress in the area is the direct result of advanced analytical technologies and chemometric applications which are highlighted in the book. |
| current opinion in structural biology: Nucleic Acid Structure and Recognition Stephen Neidle, 2002 This book provides a detailed view of the molecular structures of DNA and RNA and how they are recognised by small molecules and proteins. Extensive source material is provided, including information on relevant web sites and computer programmes. The major methods of structural investigation for nucleic acids: X-ray crystallography, NMR, and molecular modelling are reviewed and their scope and limitations (in the context of nucleic acids) discussed. Also covered are the conformational features of nucleic acid building blocks, including a description of how base-pair morphologies are analysed; the structures of DNA double helices and helical oligonucleotides, emphasising current ideas on sequence-dependent structure; and DNA-DNA interactions, including triplexes and quadruplexes. The principles of RNA folding, ribosome, and ribozyme structure are also surveyed. Both covalent and non-covalent nucleic acid interactions with small molecules are described, with the emphasis on recognition principles and sequence specific gene recognition. The principles of protein - nucleic acid are covered, focussing on regulatory proteins. Nucleic Acid Structure and Recognition will therefore equip readers with a good understanding of all the important aspects of this major field. The Nucleic Acid Database (NDB) crystallographic and NMR structures for the nucleic acid structures described in the book are freely available through the Nucleic Acid Structure and Recognition website. |
| current opinion in structural biology: Issues in Biological and Life Sciences Research: 2012 Edition , 2013-01-10 Issues in Biological and Life Sciences Research: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Life Science Research. The editors have built Issues in Biological and Life Sciences Research: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Life Science Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biological and Life Sciences Research: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| current opinion in structural biology: Protein Evolution Laszlo Patthy, 2009-03-12 This book provides an up-to-date summary of the principles of protein evolution and discusses both the methods available to analyze the evolutionary history of proteins as well as those for predicting their structure-function relationships. Includes a significantly expanded chapter on genome evolution to cover genomes of model organisms sequenced since the completion of the first edition, and organelle genome evolution Retains its reader-friendly, accessible style and organization Contains an updated glossary and new references, including a list of online reference sites |
| current opinion in structural biology: Elements of Molecular Neurobiology C. U. M. Smith, 2003-06-13 This edition of the popular text incorporates recent advances in neurobiology enabled by modern molecular biology techniques. Understanding how the brain works from a molecular level allows research to better understand behaviours, cognition, and neuropathologies. Since the appearance six years ago of the second edition, much more has been learned about the molecular biology of development and its relations with early evolution. This evodevo (as it has come to be known) framework also has a great deal of bearing on our understanding of neuropathologies as dysfunction of early onset genes can cause neurodegeneration in later life. Advances in our understanding of the genomes and proteomes of a number of organisms also greatly influence our understanding of neurobiology. * Well known and widely used as a text throughout the UK, good reviews from students and lecturers. * Good complement to Fundementals of Psychopharmacology by Brian Leonard. This book will be of particular interest to biomedical undergraduates undertaking a neuroscience unit, neuroscience postgraduates, physiologists, pharmacologists. It is also a useful basic reference for university libraries. Maurice Elphick, Queen Mary, University of London I do like this book and it is the recommended textbook for my course in Molecular Neuroscience. The major strength of the book is the overall simplicity of the format both in terms of layout and diagrams. |
| current opinion in structural biology: Issues in Biological and Life Sciences Research: 2011 Edition , 2012-01-09 Issues in Biological and Life Sciences Research: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biological and Life Sciences Research. The editors have built Issues in Biological and Life Sciences Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biological and Life Sciences Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biological and Life Sciences Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| current opinion in structural biology: Acetyltransferases—Advances in Research and Application: 2012 Edition , 2012-12-26 Acetyltransferases—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Acetyltransferases in a concise format. The editors have built Acetyltransferases—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Acetyltransferases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Acetyltransferases—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| current opinion in structural biology: Advances in Chromatin Research and Application: 2013 Edition , 2013-06-21 Advances in Chromatin Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Nucleosomes. The editors have built Advances in Chromatin Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Nucleosomes in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Chromatin Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| current opinion in structural biology: Multi-Step Enzyme Catalysis Eduardo Garcia-Junceda, 2008-11-21 The first comprehensive coverage of this unique and interdisciplinary field provides a complete overview, covering such topics as chemoenzymatic synthesis, microbial production of DNA building blocks, asymmetric transformations by coupled enzymes and much more. By combining enzymatic and synthetic organic steps, the use of multi-enzyme complexes and other techniques opens the door to reactions hitherto unknown, making this monograph of great interest to biochemists, organic chemists, and chemists working with/on organometallics, as well as catalytic chemists, biotechnologists, and those working in the pharmaceutical and fine chemical industries. |
| current opinion in structural biology: Advances in Government Research and Application: 2012 Edition , 2012-12-26 Advances in Government Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Government. The editors have built Advances in Government Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Government in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Government Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| current opinion in structural biology: Organelles—Advances in Research and Application: 2013 Edition , 2013-06-21 Organelles—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Ribosomes. The editors have built Organelles—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Ribosomes in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Organelles—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/. |
| current opinion in structural biology: Protein Design and Structure Rossen Donev, 2022-05-06 Protein Design and Structure, Volume 130 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Advances in Protein Chemistry and Structural Biology series - Includes the latest information on protein design and structure |
| current opinion in structural biology: The Encylopedia of Molecular Biology Sir John Kendrew, 2009-07-06 The Encylopaedia of Molecular Biology is a truly unique work of reference. 6000 definitions cover the entire spectrum of molecular life science The complete one-volume guide to understanding the way molecular biology is transforming medicine and agriculture Long and short entries written by over 300 of the world's finest researchers For rapid research or detailed study ... this is the A to Z of the New Biology |
| current opinion in structural biology: Challenges and Opportunities of Next-Generation Sequencing for Biomedical Research , 2012-10-04 Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics. This volume features articles on Challenges and Opportunities of Next-Generation Sequencing for Biomedical Research. - Covers reviews of methodology and research in all aspects of protein chemistry - Brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics |
| current opinion in structural biology: Characterization of Biological Membranes Mu-Ping Nieh, Frederick A. Heberle, John Katsaras, 2019-07-22 The study of membranes has become of high importance in the fields of biology, pharmaceutical chemistry and medicine, since much of what happens in a cell or in a virus involves biological membranes. The current book is an excellent introduction to the area, which explains how modern analytical methods can be applied to study biological membranes and membrane proteins and the bioprocesses they are involved to. |
| current opinion in structural biology: Why Can't I Get Better? Richard I. Horowitz, Richard Horowitz, 2013-11-12 When Dr. Richard Horowitz moved to the Hudson Valley over a decade ago to start his own medical practice, he didn't know that he would be jumping into the center of one of the fiercest, most heated medical disputes being waged today. The ongoing debate over Lyme disease as a chronic illness has made it difficult for sufferers to find care, as doctors are in many cases unable or unwilling to diagnose it. This is how once-treatable infections can become chronic, causing disabling conditions that may never be cured. In a field where the number of cases is growing each year and answers remain elusive, Horowitz has made extraordinary progress. His plan represents a paradigm shift, without which, he argues, the suffering will continue. In this book, Horowitz breaks new ground with a 16 Point Differential Diagnostic Map, the basis for his Lyme treatment plan, and an overarching approach to treating all chronic illness. He introduces MSIDS, or Multi-Systemic Infectious Disease Syndrome, a new lens on chronic illness that may prove to be an important missing link. And he covers in detail Lyme's leading symptoms and co-infections, including immune dysfunction, sleep disorders, chronic pain and neurodegenerative disorders. This book is an all-in-one source for patients of Lyme and other chronic illnesses to identify their own symptoms and work with their doctors for the best possible treatment outcome-- |
| current opinion in structural biology: How Can I Get Better? Richard Horowitz, 2017-02-14 From one of the country’s foremost doctors and now New York Times bestselling author comes a step-by-step plan for diagnosing, treating and healing Lyme and other chronic diseases. |
| current opinion in structural biology: Lead Generation Jörg Holenz, 2016-03-16 In this comprehensive two-volume resource on the topic senior lead generation medicinal chemists present a coherent view of the current methods and strategies in industrial and academic lead generation. This is the first book to combine both standard and innovative approaches in comparable breadth and depth, including several recent successful lead generation case studies published here for the first time. Beginning with a general discussion of the underlying principles and strategies, individual lead generation approaches are described in detail, highlighting their strengths and weaknesses, along with all relevant bordering disciplines like e.g. target identification and validation, predictive methods, molecular recognition or lead quality matrices. Novel lead generation approaches for challenging targets like DNA-encoded library screening or chemical biology approaches are treated here side by side with established methods as high throughput and affinity screening, knowledge- or fragment-based lead generation, and collaborative approaches. Within the entire book, a very strong focus is given to highlight the application of the presented methods, so that the reader will be able to learn from real life examples. The final part of the book presents several lead generation case studies taken from different therapeutic fields, including diabetes, cardiovascular and respiratory diseases, neuroscience, infection and tropical diseases. The result is a prime knowledge resource for medicinal chemists and for every scientist involved in lead generation. |
| current opinion in structural biology: Lead Generation, 2 Volume Set Jörg Holenz, 2016-06-27 In this comprehensive two-volume resource on the topic senior lead generation medicinal chemists present a coherent view of the current methods and strategies in industrial and academic lead generation. This is the first book to combine both standard and innovative approaches in comparable breadth and depth, including several recent successful lead generation case studies published here for the first time. Beginning with a general discussion of the underlying principles and strategies, individual lead generation approaches are described in detail, highlighting their strengths and weaknesses, along with all relevant bordering disciplines like e.g. target identification and validation, predictive methods, molecular recognition or lead quality matrices. Novel lead generation approaches for challenging targets like DNA-encoded library screening or chemical biology approaches are treated here side by side with established methods as high throughput and affinity screening, knowledge- or fragment-based lead generation, and collaborative approaches. Within the entire book, a very strong focus is given to highlight the application of the presented methods, so that the reader will be able to learn from real life examples. The final part of the book presents several lead generation case studies taken from different therapeutic fields, including diabetes, cardiovascular and respiratory diseases, neuroscience, infection and tropical diseases. The result is a prime knowledge resource for medicinal chemists and for every scientist involved in lead generation. |
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