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| data science projects in pharmaceutical industry: The Era of Artificial Intelligence, Machine Learning, and Data Science in the Pharmaceutical Industry Stephanie K. Ashenden, 2021-04-23 The Era of Artificial Intelligence, Machine Learning and Data Science in the Pharmaceutical Industry examines the drug discovery process, assessing how new technologies have improved effectiveness. Artificial intelligence and machine learning are considered the future for a wide range of disciplines and industries, including the pharmaceutical industry. In an environment where producing a single approved drug costs millions and takes many years of rigorous testing prior to its approval, reducing costs and time is of high interest. This book follows the journey that a drug company takes when producing a therapeutic, from the very beginning to ultimately benefitting a patient's life. This comprehensive resource will be useful to those working in the pharmaceutical industry, but will also be of interest to anyone doing research in chemical biology, computational chemistry, medicinal chemistry and bioinformatics. - Demonstrates how the prediction of toxic effects is performed, how to reduce costs in testing compounds, and its use in animal research - Written by the industrial teams who are conducting the work, showcasing how the technology has improved and where it should be further improved - Targets materials for a better understanding of techniques from different disciplines, thus creating a complete guide |
| data science projects in pharmaceutical industry: Trends and Innovations in Information Systems and Technologies Álvaro Rocha, Hojjat Adeli, Luís Paulo Reis, Sandra Costanzo, Irena Orovic, Fernando Moreira, 2020-05-18 This book gathers selected papers presented at the 2020 World Conference on Information Systems and Technologies (WorldCIST’20), held in Budva, Montenegro, from April 7 to 10, 2020. WorldCIST provides a global forum for researchers and practitioners to present and discuss recent results and innovations, current trends, professional experiences with and challenges regarding various aspects of modern information systems and technologies. The main topics covered are A) Information and Knowledge Management; B) Organizational Models and Information Systems; C) Software and Systems Modeling; D) Software Systems, Architectures, Applications and Tools; E) Multimedia Systems and Applications; F) Computer Networks, Mobility and Pervasive Systems; G) Intelligent and Decision Support Systems; H) Big Data Analytics and Applications; I) Human–Computer Interaction; J) Ethics, Computers & Security; K) Health Informatics; L) Information Technologies in Education; M) Information Technologies in Radiocommunications; and N) Technologies for Biomedical Applications. |
| data science projects in pharmaceutical industry: Lattice Deepayan Sarkar, 2008-02-15 Written by the author of the lattice system, this book describes lattice in considerable depth, beginning with the essentials and systematically delving into specific low levels details as necessary. No prior experience with lattice is required to read the book, although basic familiarity with R is assumed. The book contains close to 150 figures produced with lattice. Many of the examples emphasize principles of good graphical design; almost all use real data sets that are publicly available in various R packages. All code and figures in the book are also available online, along with supplementary material covering more advanced topics. |
| data science projects in pharmaceutical industry: Artificial Intelligence in Drug Discovery Nathan Brown, 2020-11-04 Following significant advances in deep learning and related areas interest in artificial intelligence (AI) has rapidly grown. In particular, the application of AI in drug discovery provides an opportunity to tackle challenges that previously have been difficult to solve, such as predicting properties, designing molecules and optimising synthetic routes. Artificial Intelligence in Drug Discovery aims to introduce the reader to AI and machine learning tools and techniques, and to outline specific challenges including designing new molecular structures, synthesis planning and simulation. Providing a wealth of information from leading experts in the field this book is ideal for students, postgraduates and established researchers in both industry and academia. |
| data science projects in pharmaceutical industry: Applications of Machine Learning Prashant Johri, Jitendra Kumar Verma, Sudip Paul, 2020-05-04 This book covers applications of machine learning in artificial intelligence. The specific topics covered include human language, heterogeneous and streaming data, unmanned systems, neural information processing, marketing and the social sciences, bioinformatics and robotics, etc. It also provides a broad range of techniques that can be successfully applied and adopted in different areas. Accordingly, the book offers an interesting and insightful read for scholars in the areas of computer vision, speech recognition, healthcare, business, marketing, and bioinformatics. |
| data science projects in pharmaceutical industry: Machine Learning and Data Science in the Oil and Gas Industry Patrick Bangert, 2021-03-04 Machine Learning and Data Science in the Oil and Gas Industry explains how machine learning can be specifically tailored to oil and gas use cases. Petroleum engineers will learn when to use machine learning, how it is already used in oil and gas operations, and how to manage the data stream moving forward. Practical in its approach, the book explains all aspects of a data science or machine learning project, including the managerial parts of it that are so often the cause for failure. Several real-life case studies round out the book with topics such as predictive maintenance, soft sensing, and forecasting. Viewed as a guide book, this manual will lead a practitioner through the journey of a data science project in the oil and gas industry circumventing the pitfalls and articulating the business value. - Chart an overview of the techniques and tools of machine learning including all the non-technological aspects necessary to be successful - Gain practical understanding of machine learning used in oil and gas operations through contributed case studies - Learn change management skills that will help gain confidence in pursuing the technology - Understand the workflow of a full-scale project and where machine learning benefits (and where it does not) |
| data science projects in pharmaceutical industry: Proceedings of the 2nd International Conference on Cognitive Based Information Processing and Applications (CIPA 2022) Bernard J. Jansen, Qingyuan Zhou, Jun Ye, 2023-04-10 This book contains papers presented at the 2nd International Conference on Cognitive based Information Processing and Applications (CIPA) in Changzhou, China, from September 22 to 23, 2022. The book is divided into a 2-volume series and the papers represent the various technological advancements in network information processing, graphics and image processing, medical care, machine learning, smart cities. It caters to postgraduate students, researchers, and practitioners specializing and working in the area of cognitive-inspired computing and information processing. |
| data science projects in pharmaceutical industry: Portfolio, Program, and Project Management in the Pharmaceutical and Biotechnology Industries Pete Harpum, 2011-09-20 This book describes the way that pharmaceutical projects and programs are currently managed, and offers views from many highly experienced practitioners from within the industry on future directions for drug program management. The book integrates portfolio, program, and project management processes as fundamental for effective and efficient drug product development. Contributing expert authors provide their view of how the projectization approach can be taken forward by the drug industry over the coming years. |
| data science projects in pharmaceutical industry: Big Data for Big Pharma Malena Johannes, 2016-06-16 Raising costs, ever-increasing regulatory hurdles, and mounting difficulties in finding the next blockbuster drug are just a few of the challenges Big Pharma currently has to face for its research and development process, the heart of its risky business. Big Data claims to be full of insights that Big Pharma need to find a way of harvesting, which could lead to new compounds. Academics, Big Data start-ups, and pharmaceutical companies have focused their research efforts on analytic tools and data technologies to store, collect, analyse, and extract these insights from massive data sets. However, the key question is whether the Big Data hype really does have the claimed accelerating effect on the complex research and development process or if it actually creates another hurdle for Big Pharma innovation. Malena Johannes' timely book sheds light on this question by examining the top 5 pharmaceutical companies and provides an overview on the status quo of Big Data applications within the pharmaceutical industry. |
| data science projects in pharmaceutical industry: Artificial Intelligence in Healthcare Adam Bohr, Kaveh Memarzadeh, 2020-06-21 Artificial Intelligence (AI) in Healthcare is more than a comprehensive introduction to artificial intelligence as a tool in the generation and analysis of healthcare data. The book is split into two sections where the first section describes the current healthcare challenges and the rise of AI in this arena. The ten following chapters are written by specialists in each area, covering the whole healthcare ecosystem. First, the AI applications in drug design and drug development are presented followed by its applications in the field of cancer diagnostics, treatment and medical imaging. Subsequently, the application of AI in medical devices and surgery are covered as well as remote patient monitoring. Finally, the book dives into the topics of security, privacy, information sharing, health insurances and legal aspects of AI in healthcare. - Highlights different data techniques in healthcare data analysis, including machine learning and data mining - Illustrates different applications and challenges across the design, implementation and management of intelligent systems and healthcare data networks - Includes applications and case studies across all areas of AI in healthcare data |
| data science projects in pharmaceutical industry: Machine Learning and Data Science in the Power Generation Industry Patrick Bangert, 2021-01-14 Machine Learning and Data Science in the Power Generation Industry explores current best practices and quantifies the value-add in developing data-oriented computational programs in the power industry, with a particular focus on thoughtfully chosen real-world case studies. It provides a set of realistic pathways for organizations seeking to develop machine learning methods, with a discussion on data selection and curation as well as organizational implementation in terms of staffing and continuing operationalization. It articulates a body of case study–driven best practices, including renewable energy sources, the smart grid, and the finances around spot markets, and forecasting. - Provides best practices on how to design and set up ML projects in power systems, including all nontechnological aspects necessary to be successful - Explores implementation pathways, explaining key ML algorithms and approaches as well as the choices that must be made, how to make them, what outcomes may be expected, and how the data must be prepared for them - Determines the specific data needs for the collection, processing, and operationalization of data within machine learning algorithms for power systems - Accompanied by numerous supporting real-world case studies, providing practical evidence of both best practices and potential pitfalls |
| data science projects in pharmaceutical industry: Solid State Development and Processing of Pharmaceutical Molecules Michael Gruss, 2021-11-15 Solid State Development and Processing of Pharmaceutical Molecules A guide to the lastest industry principles for optimizing the production of solid state active pharmaceutical ingredients Solid State Development and Processing of Pharmaceutical Molecules is an authoritative guide that covers the entire pharmaceutical value chain. The authors—noted experts on the topic—examine the importance of the solid state form of chemical and biological drugs and review the development, production, quality control, formulation, and stability of medicines. The book explores the most recent trends in the digitization and automation of the pharmaceutical production processes that reflect the need for consistent high quality. It also includes information on relevant regulatory and intellectual property considerations. This resource is aimed at professionals in the pharmaceutical industry and offers an in-depth examination of the commercially relevant issues facing developers, producers and distributors of drug substances. This important book: Provides a guide for the effective development of solid drug forms Compares different characterization methods for solid state APIs Offers a resource for understanding efficient production methods for solid state forms of chemical and biological drugs Includes information on automation, process control, and machine learning as an integral part of the development and production workflows Covers in detail the regulatory and quality control aspects of drug development Written for medicinal chemists, pharmaceutical industry professionals, pharma engineers, solid state chemists, chemical engineers, Solid State Development and Processing of Pharmaceutical Molecules reviews information on the solid state of active pharmaceutical ingredients for their efficient development and production. |
| data science projects in pharmaceutical industry: Approaching (Almost) Any Machine Learning Problem Abhishek Thakur, 2020-07-04 This is not a traditional book. The book has a lot of code. If you don't like the code first approach do not buy this book. Making code available on Github is not an option. This book is for people who have some theoretical knowledge of machine learning and deep learning and want to dive into applied machine learning. The book doesn't explain the algorithms but is more oriented towards how and what should you use to solve machine learning and deep learning problems. The book is not for you if you are looking for pure basics. The book is for you if you are looking for guidance on approaching machine learning problems. The book is best enjoyed with a cup of coffee and a laptop/workstation where you can code along. Table of contents: - Setting up your working environment - Supervised vs unsupervised learning - Cross-validation - Evaluation metrics - Arranging machine learning projects - Approaching categorical variables - Feature engineering - Feature selection - Hyperparameter optimization - Approaching image classification & segmentation - Approaching text classification/regression - Approaching ensembling and stacking - Approaching reproducible code & model serving There are no sub-headings. Important terms are written in bold. I will be answering all your queries related to the book and will be making YouTube tutorials to cover what has not been discussed in the book. To ask questions/doubts, visit this link: https://bit.ly/aamlquestions And Subscribe to my youtube channel: https://bit.ly/abhitubesub |
| data science projects in pharmaceutical industry: Data Science for Healthcare Sergio Consoli, Diego Reforgiato Recupero, Milan Petković, 2019-02-23 This book seeks to promote the exploitation of data science in healthcare systems. The focus is on advancing the automated analytical methods used to extract new knowledge from data for healthcare applications. To do so, the book draws on several interrelated disciplines, including machine learning, big data analytics, statistics, pattern recognition, computer vision, and Semantic Web technologies, and focuses on their direct application to healthcare. Building on three tutorial-like chapters on data science in healthcare, the following eleven chapters highlight success stories on the application of data science in healthcare, where data science and artificial intelligence technologies have proven to be very promising. This book is primarily intended for data scientists involved in the healthcare or medical sector. By reading this book, they will gain essential insights into the modern data science technologies needed to advance innovation for both healthcare businesses and patients. A basic grasp of data science is recommended in order to fully benefit from this book. |
| data science projects in pharmaceutical industry: Improving and Accelerating Therapeutic Development for Nervous System Disorders Institute of Medicine, Board on Health Sciences Policy, Forum on Neuroscience and Nervous System Disorders, 2014-02-06 Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials. |
| data science projects in pharmaceutical industry: Solid State Development and Processing of Pharmaceutical Molecules Michael Gruss, 2021-09-14 Solid State Development and Processing of Pharmaceutical Molecules A guide to the lastest industry principles for optimizing the production of solid state active pharmaceutical ingredients Solid State Development and Processing of Pharmaceutical Molecules is an authoritative guide that covers the entire pharmaceutical value chain. The authors—noted experts on the topic—examine the importance of the solid state form of chemical and biological drugs and review the development, production, quality control, formulation, and stability of medicines. The book explores the most recent trends in the digitization and automation of the pharmaceutical production processes that reflect the need for consistent high quality. It also includes information on relevant regulatory and intellectual property considerations. This resource is aimed at professionals in the pharmaceutical industry and offers an in-depth examination of the commercially relevant issues facing developers, producers and distributors of drug substances. This important book: Provides a guide for the effective development of solid drug forms Compares different characterization methods for solid state APIs Offers a resource for understanding efficient production methods for solid state forms of chemical and biological drugs Includes information on automation, process control, and machine learning as an integral part of the development and production workflows Covers in detail the regulatory and quality control aspects of drug development Written for medicinal chemists, pharmaceutical industry professionals, pharma engineers, solid state chemists, chemical engineers, Solid State Development and Processing of Pharmaceutical Molecules reviews information on the solid state of active pharmaceutical ingredients for their efficient development and production. |
| data science projects in pharmaceutical industry: Sharing Clinical Trial Data Institute of Medicine, Board on Health Sciences Policy, Committee on Strategies for Responsible Sharing of Clinical Trial Data, 2015-04-20 Data sharing can accelerate new discoveries by avoiding duplicative trials, stimulating new ideas for research, and enabling the maximal scientific knowledge and benefits to be gained from the efforts of clinical trial participants and investigators. At the same time, sharing clinical trial data presents risks, burdens, and challenges. These include the need to protect the privacy and honor the consent of clinical trial participants; safeguard the legitimate economic interests of sponsors; and guard against invalid secondary analyses, which could undermine trust in clinical trials or otherwise harm public health. Sharing Clinical Trial Data presents activities and strategies for the responsible sharing of clinical trial data. With the goal of increasing scientific knowledge to lead to better therapies for patients, this book identifies guiding principles and makes recommendations to maximize the benefits and minimize risks. This report offers guidance on the types of clinical trial data available at different points in the process, the points in the process at which each type of data should be shared, methods for sharing data, what groups should have access to data, and future knowledge and infrastructure needs. Responsible sharing of clinical trial data will allow other investigators to replicate published findings and carry out additional analyses, strengthen the evidence base for regulatory and clinical decisions, and increase the scientific knowledge gained from investments by the funders of clinical trials. The recommendations of Sharing Clinical Trial Data will be useful both now and well into the future as improved sharing of data leads to a stronger evidence base for treatment. This book will be of interest to stakeholders across the spectrum of research-from funders, to researchers, to journals, to physicians, and ultimately, to patients. |
| data science projects in pharmaceutical industry: Emergence of Pharmaceutical Industry Growth with Industrial IoT Approach Valentina Emilia Balas, Vijender Kumar Solanki, Raghvendra Kumar, 2019-09-24 Emergence of Pharmaceutical Industry Growth with Industrial IoT Approach uses an innovative approach to explore how the Internet of Things (IoT) and big data can improve approaches, create efficiencies and make discoveries. Rapid growth of the IoT has encouraged many companies in the manufacturing sector to make use of this technology to unlock its potential. Pharmaceutical manufacturing companies are no exception to this, as IoT has the potential to revolutionize aspects of the pharmaceutical manufacturing process, from drug discovery to manufacturing. Using clear, concise language and real world case studies, this book discusses systems level from both a human-factors point-of-view and the perspective of networking, databases, privacy and anti-spoofing. The wide variety of topics presented offers readers multiple perspectives on a how to integrate the Internet of Things into pharmaceutical manufacturing. - Covers efficiency improvements of pharmaceutical manufacturing through IoT/Big Data approaches - Explores cutting-edge technologies through sensor enabled environment in the pharmaceutical industry - Discusses the systems level from both a human-factors point-of-view and the perspective of networking, databases, privacy and anti-spoofing |
| data science projects in pharmaceutical industry: Applied Data Science Martin Braschler, Thilo Stadelmann, Kurt Stockinger, 2019-06-13 This book has two main goals: to define data science through the work of data scientists and their results, namely data products, while simultaneously providing the reader with relevant lessons learned from applied data science projects at the intersection of academia and industry. As such, it is not a replacement for a classical textbook (i.e., it does not elaborate on fundamentals of methods and principles described elsewhere), but systematically highlights the connection between theory, on the one hand, and its application in specific use cases, on the other. With these goals in mind, the book is divided into three parts: Part I pays tribute to the interdisciplinary nature of data science and provides a common understanding of data science terminology for readers with different backgrounds. These six chapters are geared towards drawing a consistent picture of data science and were predominantly written by the editors themselves. Part II then broadens the spectrum by presenting views and insights from diverse authors – some from academia and some from industry, ranging from financial to health and from manufacturing to e-commerce. Each of these chapters describes a fundamental principle, method or tool in data science by analyzing specific use cases and drawing concrete conclusions from them. The case studies presented, and the methods and tools applied, represent the nuts and bolts of data science. Finally, Part III was again written from the perspective of the editors and summarizes the lessons learned that have been distilled from the case studies in Part II. The section can be viewed as a meta-study on data science across a broad range of domains, viewpoints and fields. Moreover, it provides answers to the question of what the mission-critical factors for success in different data science undertakings are. The book targets professionals as well as students of data science: first, practicing data scientists in industry and academia who want to broaden their scope and expand their knowledge by drawing on the authors’ combined experience. Second, decision makers in businesses who face the challenge of creating or implementing a data-driven strategy and who want to learn from success stories spanning a range of industries. Third, students of data science who want to understand both the theoretical and practical aspects of data science, vetted by real-world case studies at the intersection of academia and industry. |
| data science projects in pharmaceutical industry: Fundamentals of Clinical Data Science Pieter Kubben, Michel Dumontier, Andre Dekker, 2018-12-21 This open access book comprehensively covers the fundamentals of clinical data science, focusing on data collection, modelling and clinical applications. Topics covered in the first section on data collection include: data sources, data at scale (big data), data stewardship (FAIR data) and related privacy concerns. Aspects of predictive modelling using techniques such as classification, regression or clustering, and prediction model validation will be covered in the second section. The third section covers aspects of (mobile) clinical decision support systems, operational excellence and value-based healthcare. Fundamentals of Clinical Data Science is an essential resource for healthcare professionals and IT consultants intending to develop and refine their skills in personalized medicine, using solutions based on large datasets from electronic health records or telemonitoring programmes. The book’s promise is “no math, no code”and will explain the topics in a style that is optimized for a healthcare audience. |
| data science projects in pharmaceutical industry: Encyclopedia of Data Science and Machine Learning Wang, John, 2023-01-20 Big data and machine learning are driving the Fourth Industrial Revolution. With the age of big data upon us, we risk drowning in a flood of digital data. Big data has now become a critical part of both the business world and daily life, as the synthesis and synergy of machine learning and big data has enormous potential. Big data and machine learning are projected to not only maximize citizen wealth, but also promote societal health. As big data continues to evolve and the demand for professionals in the field increases, access to the most current information about the concepts, issues, trends, and technologies in this interdisciplinary area is needed. The Encyclopedia of Data Science and Machine Learning examines current, state-of-the-art research in the areas of data science, machine learning, data mining, and more. It provides an international forum for experts within these fields to advance the knowledge and practice in all facets of big data and machine learning, emphasizing emerging theories, principals, models, processes, and applications to inspire and circulate innovative findings into research, business, and communities. Covering topics such as benefit management, recommendation system analysis, and global software development, this expansive reference provides a dynamic resource for data scientists, data analysts, computer scientists, technical managers, corporate executives, students and educators of higher education, government officials, researchers, and academicians. |
| data science projects in pharmaceutical industry: Why Data Science Projects Fail Douglas Gray, Evan Shellshear, 2024-09-05 The field of artificial intelligence, data science, and analytics is crippling itself. Exaggerated promises of unrealistic technologies, simplifications of complex projects, and marketing hype are leading to an erosion of trust in one of our most critical approaches to making decisions: data driven. This book aims to fix this by countering the AI hype with a dose of realism. Written by two experts in the field, the authors firmly believe in the power of mathematics, computing, and analytics, but if false expectations are set and practitioners and leaders don’t fully understand everything that really goes into data science projects, then a stunning 80% (or more) of analytics projects will continue to fail, costing enterprises and society hundreds of billions of dollars, and leading to non-experts abandoning one of the most important data-driven decision-making capabilities altogether. For the first time, business leaders, practitioners, students, and interested laypeople will learn what really makes a data science project successful. By illustrating with many personal stories, the authors reveal the harsh realities of implementing AI and analytics. |
| data science projects in pharmaceutical industry: Open Source Software in Life Science Research Lee Harland, Mark Forster, 2012-10-31 The free/open source approach has grown from a minor activity to become a significant producer of robust, task-orientated software for a wide variety of situations and applications. To life science informatics groups, these systems present an appealing proposition - high quality software at a very attractive price. Open source software in life science research considers how industry and applied research groups have embraced these resources, discussing practical implementations that address real-world business problems.The book is divided into four parts. Part one looks at laboratory data management and chemical informatics, covering software such as Bioclipse, OpenTox, ImageJ and KNIME. In part two, the focus turns to genomics and bioinformatics tools, with chapters examining GenomicsTools and EBI Atlas software, as well as the practicalities of setting up an 'omics' platform and managing large volumes of data. Chapters in part three examine information and knowledge management, covering a range of topics including software for web-based collaboration, open source search and visualisation technologies for scientific business applications, and specific software such as DesignTracker and Utopia Documents. Part four looks at semantic technologies such as Semantic MediaWiki, TripleMap and Chem2Bio2RDF, before part five examines clinical analytics, and validation and regulatory compliance of free/open source software. Finally, the book concludes by looking at future perspectives and the economics and free/open source software in industry. - Discusses a broad range of applications from a variety of sectors - Provides a unique perspective on work normally performed behind closed doors - Highlights the criteria used to compare and assess different approaches to solving problems |
| data science projects in pharmaceutical industry: Research and Development in the Pharmaceutical Industry (A CBO Study) Congressional Budget Office, 2013-06-09 Perceptions that the pace of new-drug development has slowed and that the pharmaceutical industry is highly profitable have sparked concerns that significant problems loom for future drug development. This Congressional Budget Office (CBO) study-prepared at the request of the Senate Majority Leader-reviews basic facts about the drug industry's recent spending on research and development (R&D) and its output of new drugs. The study also examines issues relating to the costs of R&D, the federal government's role in pharmaceutical research, the performance of the pharmaceutical industry in developing innovative drugs, and the role of expected profits in private firms' decisions about investing in drug R&D. In keeping with CBO's mandate to provide objective, impartial analysis, the study makes no recommendations. David H. Austin prepared this report under the supervision of Joseph Kile and David Moore. Colin Baker provided valuable consultation... |
| data science projects in pharmaceutical industry: Information and Knowledge in Internet of Things Teresa Guarda, Sajid Anwar, Marcelo Leon, Filipe Jorge Mota Pinto, 2021-10-06 This book provides readers with an insight into information and knowledge in the Internet of Things, in particular an investigation of data management and processing, information extraction, technology, knowledge management, knowledge sharing, knowledge co-creation, knowledge integration, and the development of new intelligent services available anytime, anywhere, by anyone. The authors show how IoT enables communication and ubiquitous computing between global citizens, networked machines and physical objects, providing a promising vision of the future integrating the real world of knowledge agents and things with the virtual world of information. |
| data science projects in pharmaceutical industry: Machine Learning for Drug Discovery Marcelo C. R. Melo, Jacqueline R. M. A. Maasch, Cesar de la Fuente-Nunez, 2022-03-11 Machine Learning for Drug Discovery is designed to suit the needs of graduate students, advanced undergraduates, chemists or biologists otherwise new to this research domain with minimal previous exposure to Machine Learning (ML) methods, or computational scientists with minimal exposure to medicinal chemistry. The e-book covers basic algorithmic theory, data representation methods, and generative modeling at a high level. The authors spotlight antibiotic discovery as a case study in ML for drug development and discuss diverse applications in drug-likeness prediction, antimicrobial resistance, and areas for future inquiry. For a more dynamic learning experience, open-source code demonstrations in Python are included. |
| data science projects in pharmaceutical industry: Proceedings of International Conference on Information Technology and Applications Sajid Anwar, Abrar Ullah, Álvaro Rocha, Maria José Sousa, 2023-05-18 This book includes high-quality papers presented at 16th International Conference on Information Technology and Applications (ICITA 2022), held in Lisbon, Portugal during October 20–22, 2022. The book presents original research work of academics and industry professionals to exchange their knowledge of the state-of-the-art research and development in information technology and applications. The topics covered in the book are cloud computing, business process engineering, machine learning, evolutionary computing, big data analytics, Internet of things and cyber-physical systems, information and knowledge management, computer vision and image processing, computer graphics and games programming, mobile computing, ontology engineering, software and systems modeling, human–computer interaction, online learning / e-learning, computer networks, and web engineering. |
| data science projects in pharmaceutical industry: Business Intelligence Demystified Anoop Kumar V K, 2021-09-25 Clear your doubts about Business Intelligence and start your new journey KEY FEATURES ● Includes successful methods and innovative ideas to achieve success with BI. ● Vendor-neutral, unbiased, and based on experience. ● Highlights practical challenges in BI journeys. ● Covers financial aspects along with technical aspects. ● Showcases multiple BI organization models and the structure of BI teams. DESCRIPTION The book demystifies misconceptions and misinformation about BI. It provides clarity to almost everything related to BI in a simplified and unbiased way. It covers topics right from the definition of BI, terms used in the BI definition, coinage of BI, details of the different main uses of BI, processes that support the main uses, side benefits, and the level of importance of BI, various types of BI based on various parameters, main phases in the BI journey and the challenges faced in each of the phases in the BI journey. It clarifies myths about self-service BI and real-time BI. The book covers the structure of a typical internal BI team, BI organizational models, and the main roles in BI. It also clarifies the doubts around roles in BI. It explores the different components that add to the cost of BI and explains how to calculate the total cost of the ownership of BI and ROI for BI. It covers several ideas, including unconventional ideas to achieve BI success and also learn about IBI. It explains the different types of BI architectures, commonly used technologies, tools, and concepts in BI and provides clarity about the boundary of BI w.r.t technologies, tools, and concepts. The book helps you lay a very strong foundation and provides the right perspective about BI. It enables you to start or restart your journey with BI. WHAT YOU WILL LEARN ● Builds a strong conceptual foundation in BI. ● Gives the right perspective and clarity on BI uses, challenges, and architectures. ● Enables you to make the right decisions on the BI structure, organization model, and budget. ● Explains which type of BI solution is required for your business. ● Applies successful BI ideas. WHO THIS BOOK IS FOR This book is a must-read for business managers, BI aspirants, CxOs, and all those who want to drive the business value with data-driven insights. TABLE OF CONTENTS 1. What is Business Intelligence? 2. Why do Businesses need BI? 3. Types of Business Intelligence 4. Challenges in Business Intelligence 5. Roles in Business Intelligence 6. Financials of Business Intelligence 7. Ideas for Success with BI 8. Introduction to IBI 9. BI Architectures 10. Demystify Tech, Tools, and Concepts in BI |
| data science projects in pharmaceutical industry: Executing Data Quality Projects Danette McGilvray, 2021-05-27 Executing Data Quality Projects, Second Edition presents a structured yet flexible approach for creating, improving, sustaining and managing the quality of data and information within any organization. Studies show that data quality problems are costing businesses billions of dollars each year, with poor data linked to waste and inefficiency, damaged credibility among customers and suppliers, and an organizational inability to make sound decisions. Help is here! This book describes a proven Ten Step approach that combines a conceptual framework for understanding information quality with techniques, tools, and instructions for practically putting the approach to work – with the end result of high-quality trusted data and information, so critical to today's data-dependent organizations. The Ten Steps approach applies to all types of data and all types of organizations – for-profit in any industry, non-profit, government, education, healthcare, science, research, and medicine. This book includes numerous templates, detailed examples, and practical advice for executing every step. At the same time, readers are advised on how to select relevant steps and apply them in different ways to best address the many situations they will face. The layout allows for quick reference with an easy-to-use format highlighting key concepts and definitions, important checkpoints, communication activities, best practices, and warnings. The experience of actual clients and users of the Ten Steps provide real examples of outputs for the steps plus highlighted, sidebar case studies called Ten Steps in Action. This book uses projects as the vehicle for data quality work and the word broadly to include: 1) focused data quality improvement projects, such as improving data used in supply chain management, 2) data quality activities in other projects such as building new applications and migrating data from legacy systems, integrating data because of mergers and acquisitions, or untangling data due to organizational breakups, and 3) ad hoc use of data quality steps, techniques, or activities in the course of daily work. The Ten Steps approach can also be used to enrich an organization's standard SDLC (whether sequential or Agile) and it complements general improvement methodologies such as six sigma or lean. No two data quality projects are the same but the flexible nature of the Ten Steps means the methodology can be applied to all. The new Second Edition highlights topics such as artificial intelligence and machine learning, Internet of Things, security and privacy, analytics, legal and regulatory requirements, data science, big data, data lakes, and cloud computing, among others, to show their dependence on data and information and why data quality is more relevant and critical now than ever before. - Includes concrete instructions, numerous templates, and practical advice for executing every step of The Ten Steps approach - Contains real examples from around the world, gleaned from the author's consulting practice and from those who implemented based on her training courses and the earlier edition of the book - Allows for quick reference with an easy-to-use format highlighting key concepts and definitions, important checkpoints, communication activities, and best practices - A companion Web site includes links to numerous data quality resources, including many of the templates featured in the text, quick summaries of key ideas from the Ten Steps methodology, and other tools and information that are available online |
| data science projects in pharmaceutical industry: Data Science, AI, and Machine Learning in Drug Development Harry Yang, 2022-10-04 The confluence of big data, artificial intelligence (AI), and machine learning (ML) has led to a paradigm shift in how innovative medicines are developed and healthcare delivered. To fully capitalize on these technological advances, it is essential to systematically harness data from diverse sources and leverage digital technologies and advanced analytics to enable data-driven decisions. Data science stands at a unique moment of opportunity to lead such a transformative change. Intended to be a single source of information, Data Science, AI, and Machine Learning in Drug Research and Development covers a wide range of topics on the changing landscape of drug R & D, emerging applications of big data, AI and ML in drug development, and the build of robust data science organizations to drive biopharmaceutical digital transformations. Features Provides a comprehensive review of challenges and opportunities as related to the applications of big data, AI, and ML in the entire spectrum of drug R & D Discusses regulatory developments in leveraging big data and advanced analytics in drug review and approval Offers a balanced approach to data science organization build Presents real-world examples of AI-powered solutions to a host of issues in the lifecycle of drug development Affords sufficient context for each problem and provides a detailed description of solutions suitable for practitioners with limited data science expertise |
| data science projects in pharmaceutical industry: AI Pharma: Artificial Intelligence in Drug Discovery and Development Daniel D. Lee, 2024-08-12 AI Pharma: Artificial Intelligence in Drug Discovery and Development is a comprehensive exploration of how artificial intelligence is reshaping the pharmaceutical industry. It reveals how machine learning, deep learning, and other advanced technologies are revolutionizing drug discovery and development. The book meticulously charts the evolution of AI's role, starting from the surge in data collection and processing to the latest breakthroughs in predictive modeling. It unveils AI's transformative impact on research and development, delving into how AI tools streamline target identification, molecule generation, and clinical trials, leading to faster, more accurate results. Key industry experts share insights on the challenges of navigating the vast amount of data produced, stressing the importance of data cleaning, curation, and ethical considerations in collection. Case studies highlight how startups and leading companies use AI algorithms for deep learning in drug development, identifying disease targets and generating new compounds with unprecedented precision. The book emphasizes practical applications, like predictive models for toxicity and safety in preclinical trials and patient recruitment optimization in clinical trials. Additionally, it tackles the intersection of AI with emerging technologies like the Internet of Medical Things (IoMT) and blockchain, showcasing how these complement AI in securing data and enhancing pharmaceutical supply chains. Readers will gain a deep understanding of the regulatory landscape, exploring FDA guidelines and global regulations that shape AI adoption. Interwoven throughout are the voices of thought leaders who address legal and ethical challenges, highlight the significance of partnerships, and stress the need for transparent and trustworthy AI models. They emphasize cross-disciplinary collaboration and tailored training strategies to cultivate AI talent that meets the growing needs of pharma. By examining the future of deep learning, computational research, and explainable AI, the book provides a strategic roadmap that researchers, policymakers, and developers can follow. Ultimately, this book is not only a roadmap but also a clarion call, urging stakeholders to build collaborative ecosystems that harness AI's potential for innovative pharmaceutical research and development. Through a rich, detailed narrative, readers are guided to understand the profound implications and exciting opportunities that await in this AI-driven pharmaceutical landscape |
| data science projects in pharmaceutical industry: Bioinformatics Tools for Pharmaceutical Drug Product Development Vivek Chavda, Krishnan Anand, Vasso Apostolopoulos, 2023-02-09 BIOINFORMATICS TOOLS FOR Pharmaceutical DRUG PRODUCT DLEVELOPMENT A timely book that details bioinformatics tools, artificial intelligence, machine learning, computational methods, protein interactions, peptide-based drug design, and omics technologies, for drug development in the pharmaceutical and medical sciences industries. The book contains 17 chapters categorized into 3 sections. The first section presents the latest information on bioinformatics tools, artificial intelligence, machine learning, computational methods, protein interactions, peptide-based drug design, and omics technologies. The following 2 sections include bioinformatics tools for the pharmaceutical sector and the healthcare sector. Bioinformatics brings a new era in research to accelerate drug target and vaccine design development, improving validation approaches as well as facilitating and identifying side effects and predicting drug resistance. As such, this will aid in more successful drug candidates from discovery to clinical trials to the market, and most importantly make it a more cost-effective process overall. Readers will find in this book: Applications of bioinformatics tools for pharmaceutical drug product development like process development, pre-clinical development, clinical development, commercialization of the product, etc.; The ever-expanding application of this novel technology and discusses some of the unique challenges associated with such an approach; The broad and deep background, as well as updates, on recent advances in both medicine and AI/ML that enable the application of these cutting-edge bioinformatics tools. Audience The book will be used by researchers and scientists in academia and industry including drug developers, computational biochemists, bioinformaticians, immunologists, pharmaceutical and medical sciences, as well as those in artificial intelligence and machine learning. |
| data science projects in pharmaceutical industry: Sharing Clinical Research Data Institute of Medicine, Board on Health Care Services, Board on Health Sciences Policy, Roundtable on Translating Genomic-Based Research for Health, National Cancer Policy Forum, Forum on Neuroscience and Nervous System Disorders, Forum on Drug Discovery, Development, and Translation, 2013-06-07 Pharmaceutical companies, academic researchers, and government agencies such as the Food and Drug Administration and the National Institutes of Health all possess large quantities of clinical research data. If these data were shared more widely within and across sectors, the resulting research advances derived from data pooling and analysis could improve public health, enhance patient safety, and spur drug development. Data sharing can also increase public trust in clinical trials and conclusions derived from them by lending transparency to the clinical research process. Much of this information, however, is never shared. Retention of clinical research data by investigators and within organizations may represent lost opportunities in biomedical research. Despite the potential benefits that could be accrued from pooling and analysis of shared data, barriers to data sharing faced by researchers in industry include concerns about data mining, erroneous secondary analyses of data, and unwarranted litigation, as well as a desire to protect confidential commercial information. Academic partners face significant cultural barriers to sharing data and participating in longer term collaborative efforts that stem from a desire to protect intellectual autonomy and a career advancement system built on priority of publication and citation requirements. Some barriers, like the need to protect patient privacy, pre- sent challenges for both sectors. Looking ahead, there are also a number of technical challenges to be faced in analyzing potentially large and heterogeneous datasets. This public workshop focused on strategies to facilitate sharing of clinical research data in order to advance scientific knowledge and public health. While the workshop focused on sharing of data from preplanned interventional studies of human subjects, models and projects involving sharing of other clinical data types were considered to the extent that they provided lessons learned and best practices. The workshop objectives were to examine the benefits of sharing of clinical research data from all sectors and among these sectors, including, for example: benefits to the research and development enterprise and benefits to the analysis of safety and efficacy. Sharing Clinical Research Data: Workshop Summary identifies barriers and challenges to sharing clinical research data, explores strategies to address these barriers and challenges, including identifying priority actions and low-hanging fruit opportunities, and discusses strategies for using these potentially large datasets to facilitate scientific and public health advances. |
| data science projects in pharmaceutical industry: Clustering in Bioinformatics and Drug Discovery John David MacCuish, Norah E. MacCuish, 2010-11-15 With a DVD of color figures, Clustering in Bioinformatics and Drug Discovery provides an expert guide on extracting the most pertinent information from pharmaceutical and biomedical data. It offers a concise overview of common and recent clustering methods used in bioinformatics and drug discovery.Setting the stage for subsequent material, the firs |
| data science projects in pharmaceutical industry: Concepts in Pharmaceutical Biotechnology and Drug Development Sankhadip Bose, |
| data science projects in pharmaceutical industry: Perspectives on Data Science for Software Engineering Tim Menzies, Laurie Williams, Thomas Zimmermann, 2016-07-14 Perspectives on Data Science for Software Engineering presents the best practices of seasoned data miners in software engineering. The idea for this book was created during the 2014 conference at Dagstuhl, an invitation-only gathering of leading computer scientists who meet to identify and discuss cutting-edge informatics topics. At the 2014 conference, the concept of how to transfer the knowledge of experts from seasoned software engineers and data scientists to newcomers in the field highlighted many discussions. While there are many books covering data mining and software engineering basics, they present only the fundamentals and lack the perspective that comes from real-world experience. This book offers unique insights into the wisdom of the community's leaders gathered to share hard-won lessons from the trenches. Ideas are presented in digestible chapters designed to be applicable across many domains. Topics included cover data collection, data sharing, data mining, and how to utilize these techniques in successful software projects. Newcomers to software engineering data science will learn the tips and tricks of the trade, while more experienced data scientists will benefit from war stories that show what traps to avoid. - Presents the wisdom of community experts, derived from a summit on software analytics - Provides contributed chapters that share discrete ideas and technique from the trenches - Covers top areas of concern, including mining security and social data, data visualization, and cloud-based data - Presented in clear chapters designed to be applicable across many domains |
| data science projects in pharmaceutical industry: Data Science for Economics and Finance Sergio Consoli, Diego Reforgiato Recupero, Michaela Saisana, 2021 This open access book covers the use of data science, including advanced machine learning, big data analytics, Semantic Web technologies, natural language processing, social media analysis, time series analysis, among others, for applications in economics and finance. In addition, it shows some successful applications of advanced data science solutions used to extract new knowledge from data in order to improve economic forecasting models. The book starts with an introduction on the use of data science technologies in economics and finance and is followed by thirteen chapters showing success stories of the application of specific data science methodologies, touching on particular topics related to novel big data sources and technologies for economic analysis (e.g. social media and news); big data models leveraging on supervised/unsupervised (deep) machine learning; natural language processing to build economic and financial indicators; and forecasting and nowcasting of economic variables through time series analysis. This book is relevant to all stakeholders involved in digital and data-intensive research in economics and finance, helping them to understand the main opportunities and challenges, become familiar with the latest methodological findings, and learn how to use and evaluate the performances of novel tools and frameworks. It primarily targets data scientists and business analysts exploiting data science technologies, and it will also be a useful resource to research students in disciplines and courses related to these topics. Overall, readers will learn modern and effective data science solutions to create tangible innovations for economic and financial applications. |
| data science projects in pharmaceutical industry: AI in Health Tom Lawry, 2020-02-05 We are in the early stages of the next big platform shift in healthcare computing. Fueled by Artificial Intelligence (AI) and the Cloud, this shift is already transforming the way health and medical services are provided. As the industry transitions from static digital repositories to intelligent systems, there will be winners and losers in the race to innovate and automate the provision of services. Critical to success will be the role leaders play in shaping the use of AI to be less artificial and more intelligent in support of improving processes to deliver care and keep people healthy and productive across all care settings. This book defines key technical, process, people, and ethical issues that need to be understood and addressed in successfully planning and executing an enterprise-wide AI plan. It provides clinical and business leaders with a framework for moving organizations from the aspiration to execution of intelligent systems to improve clinical, operational, and financial performance. |
| data science projects in pharmaceutical industry: Proceedings of the 3rd International Conference on Cognitive Based Information Processing and Applications—Volume 3 Bernard J. Jansen, |
| data science projects in pharmaceutical industry: Application of Project Management Principles to the Management of Pharmaceutical R&D Projects Thomas Catalano, 2020-11-05 Dr. Catalano has for the last ten years been doing consulting for the Pharmaceutical Industry. During his consulting he discovered that small businesses such as, generic, startups, and virtual companies do not have the budget or the resources to apply the computer software utilized in project management and therefore do not apply project management principles in their business model. This reduces their effectiveness and increases their operating cost. Application of Project Management Principles to the Management of Pharmaceutical R&D Projects is presented as a paper-based system for completing all the critical activities needed apply the project management system. This will allow these small business to take advantage of the project management principles and gain all the advantages of the system. This book will be beneficial for beginners to understand the concepts of project management and for small pharmaceutical companies to apply the principles of project management to their business model. |
Data and Digital Outputs Management Plan (DDOMP)
Data and Digital Outputs Management Plan (DDOMP)
Building New Tools for Data Sharing and Reuse through a …
Jan 10, 2019 · The SEI CRA will closely link research thinking and technological innovation toward accelerating the full path of discovery-driven data use and open science. This will enable a …
Open Data Policy and Principles - Belmont Forum
The data policy includes the following principles: Data should be: Discoverable through catalogues and search engines; Accessible as open data by default, and made available with …
Belmont Forum Adopts Open Data Principles for Environmental …
Jan 27, 2016 · Adoption of the open data policy and principles is one of five recommendations in A Place to Stand: e-Infrastructures and Data Management for Global Change Research, …
Belmont Forum Data Accessibility Statement and Policy
The DAS encourages researchers to plan for the longevity, reusability, and stability of the data attached to their research publications and results. Access to data promotes reproducibility, …
Climate-Induced Migration in Africa and Beyond: Big Data and …
CLIMB will also leverage earth observation and social media data, and combine them with survey and official statistical data. This holistic approach will allow us to analyze migration process …
Advancing Resilience in Low Income Housing Using Climate …
Jun 4, 2020 · Environmental sustainability and public health considerations will be included. Machine Learning and Big Data Analytics will be used to identify optimal disaster resilient …
Belmont Forum
What is the Belmont Forum? The Belmont Forum is an international partnership that mobilizes funding of environmental change research and accelerates its delivery to remove critical …
Waterproofing Data: Engaging Stakeholders in Sustainable Flood …
Apr 26, 2018 · Waterproofing Data investigates the governance of water-related risks, with a focus on social and cultural aspects of data practices. Typically, data flows up from local levels to …
Data Management Annex (Version 1.4) - Belmont Forum
A full Data Management Plan (DMP) for an awarded Belmont Forum CRA project is a living, actively updated document that describes the data management life cycle for the data to be …
Data and Digital Outputs Management Plan (DDOMP)
Data and Digital Outputs Management Plan (DDOMP)
Building New Tools for Data Sharing and Reuse through a …
Jan 10, 2019 · The SEI CRA will closely link research thinking and technological innovation toward accelerating the full path of discovery-driven data use and open science. This will …
Open Data Policy and Principles - Belmont Forum
The data policy includes the following principles: Data should be: Discoverable through catalogues and search engines; Accessible as open data by default, and made available with …
Belmont Forum Adopts Open Data Principles for Environmental …
Jan 27, 2016 · Adoption of the open data policy and principles is one of five recommendations in A Place to Stand: e-Infrastructures and Data Management for Global Change Research, …
Belmont Forum Data Accessibility Statement and Policy
The DAS encourages researchers to plan for the longevity, reusability, and stability of the data attached to their research publications and results. Access to data promotes reproducibility, …
Climate-Induced Migration in Africa and Beyond: Big Data and …
CLIMB will also leverage earth observation and social media data, and combine them with survey and official statistical data. This holistic approach will allow us to analyze migration process …
Advancing Resilience in Low Income Housing Using Climate …
Jun 4, 2020 · Environmental sustainability and public health considerations will be included. Machine Learning and Big Data Analytics will be used to identify optimal disaster resilient …
Belmont Forum
What is the Belmont Forum? The Belmont Forum is an international partnership that mobilizes funding of environmental change research and accelerates its delivery to remove critical …
Waterproofing Data: Engaging Stakeholders in Sustainable Flood …
Apr 26, 2018 · Waterproofing Data investigates the governance of water-related risks, with a focus on social and cultural aspects of data practices. Typically, data flows up from local levels …
Data Management Annex (Version 1.4) - Belmont Forum
A full Data Management Plan (DMP) for an awarded Belmont Forum CRA project is a living, actively updated document that describes the data management life cycle for the data to be …
