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| data science and pharmacy: The Era of Artificial Intelligence, Machine Learning, and Data Science in the Pharmaceutical Industry Stephanie K. Ashenden, 2021-04-23 The Era of Artificial Intelligence, Machine Learning and Data Science in the Pharmaceutical Industry examines the drug discovery process, assessing how new technologies have improved effectiveness. Artificial intelligence and machine learning are considered the future for a wide range of disciplines and industries, including the pharmaceutical industry. In an environment where producing a single approved drug costs millions and takes many years of rigorous testing prior to its approval, reducing costs and time is of high interest. This book follows the journey that a drug company takes when producing a therapeutic, from the very beginning to ultimately benefitting a patient's life. This comprehensive resource will be useful to those working in the pharmaceutical industry, but will also be of interest to anyone doing research in chemical biology, computational chemistry, medicinal chemistry and bioinformatics. - Demonstrates how the prediction of toxic effects is performed, how to reduce costs in testing compounds, and its use in animal research - Written by the industrial teams who are conducting the work, showcasing how the technology has improved and where it should be further improved - Targets materials for a better understanding of techniques from different disciplines, thus creating a complete guide |
| data science and pharmacy: Leveraging Data Science for Global Health Leo Anthony Celi, Maimuna S. Majumder, Patricia Ordóñez, Juan Sebastian Osorio, Kenneth E. Paik, Melek Somai, 2020-07-31 This open access book explores ways to leverage information technology and machine learning to combat disease and promote health, especially in resource-constrained settings. It focuses on digital disease surveillance through the application of machine learning to non-traditional data sources. Developing countries are uniquely prone to large-scale emerging infectious disease outbreaks due to disruption of ecosystems, civil unrest, and poor healthcare infrastructure – and without comprehensive surveillance, delays in outbreak identification, resource deployment, and case management can be catastrophic. In combination with context-informed analytics, students will learn how non-traditional digital disease data sources – including news media, social media, Google Trends, and Google Street View – can fill critical knowledge gaps and help inform on-the-ground decision-making when formal surveillance systems are insufficient. |
| data science and pharmacy: Data Science for Healthcare Sergio Consoli, Diego Reforgiato Recupero, Milan Petković, 2019-02-23 This book seeks to promote the exploitation of data science in healthcare systems. The focus is on advancing the automated analytical methods used to extract new knowledge from data for healthcare applications. To do so, the book draws on several interrelated disciplines, including machine learning, big data analytics, statistics, pattern recognition, computer vision, and Semantic Web technologies, and focuses on their direct application to healthcare. Building on three tutorial-like chapters on data science in healthcare, the following eleven chapters highlight success stories on the application of data science in healthcare, where data science and artificial intelligence technologies have proven to be very promising. This book is primarily intended for data scientists involved in the healthcare or medical sector. By reading this book, they will gain essential insights into the modern data science technologies needed to advance innovation for both healthcare businesses and patients. A basic grasp of data science is recommended in order to fully benefit from this book. |
| data science and pharmacy: R for Health Data Science Ewen Harrison, Riinu Pius, 2020-12-31 In this age of information, the manipulation, analysis, and interpretation of data have become a fundamental part of professional life; nowhere more so than in the delivery of healthcare. From the understanding of disease and the development of new treatments, to the diagnosis and management of individual patients, the use of data and technology is now an integral part of the business of healthcare. Those working in healthcare interact daily with data, often without realising it. The conversion of this avalanche of information to useful knowledge is essential for high-quality patient care. R for Health Data Science includes everything a healthcare professional needs to go from R novice to R guru. By the end of this book, you will be taking a sophisticated approach to health data science with beautiful visualisations, elegant tables, and nuanced analyses. Features Provides an introduction to the fundamentals of R for healthcare professionals Highlights the most popular statistical approaches to health data science Written to be as accessible as possible with minimal mathematics Emphasises the importance of truly understanding the underlying data through the use of plots Includes numerous examples that can be adapted for your own data Helps you create publishable documents and collaborate across teams With this book, you are in safe hands – Prof. Harrison is a clinician and Dr. Pius is a data scientist, bringing 25 years’ combined experience of using R at the coal face. This content has been taught to hundreds of individuals from a variety of backgrounds, from rank beginners to experts moving to R from other platforms. |
| data science and pharmacy: Data Smart John W. Foreman, 2013-10-31 Data Science gets thrown around in the press like it'smagic. Major retailers are predicting everything from when theircustomers are pregnant to when they want a new pair of ChuckTaylors. It's a brave new world where seemingly meaningless datacan be transformed into valuable insight to drive smart businessdecisions. But how does one exactly do data science? Do you have to hireone of these priests of the dark arts, the data scientist, toextract this gold from your data? Nope. Data science is little more than using straight-forward steps toprocess raw data into actionable insight. And in DataSmart, author and data scientist John Foreman will show you howthat's done within the familiar environment of aspreadsheet. Why a spreadsheet? It's comfortable! You get to look at the dataevery step of the way, building confidence as you learn the tricksof the trade. Plus, spreadsheets are a vendor-neutral place tolearn data science without the hype. But don't let the Excel sheets fool you. This is a book forthose serious about learning the analytic techniques, the math andthe magic, behind big data. Each chapter will cover a different technique in aspreadsheet so you can follow along: Mathematical optimization, including non-linear programming andgenetic algorithms Clustering via k-means, spherical k-means, and graphmodularity Data mining in graphs, such as outlier detection Supervised AI through logistic regression, ensemble models, andbag-of-words models Forecasting, seasonal adjustments, and prediction intervalsthrough monte carlo simulation Moving from spreadsheets into the R programming language You get your hands dirty as you work alongside John through eachtechnique. But never fear, the topics are readily applicable andthe author laces humor throughout. You'll even learnwhat a dead squirrel has to do with optimization modeling, whichyou no doubt are dying to know. |
| data science and pharmacy: Healthcare Data Analytics Chandan K. Reddy, Charu C. Aggarwal, 2015-06-23 At the intersection of computer science and healthcare, data analytics has emerged as a promising tool for solving problems across many healthcare-related disciplines. Supplying a comprehensive overview of recent healthcare analytics research, Healthcare Data Analytics provides a clear understanding of the analytical techniques currently available |
| data science and pharmacy: Lattice Deepayan Sarkar, 2008-02-15 Written by the author of the lattice system, this book describes lattice in considerable depth, beginning with the essentials and systematically delving into specific low levels details as necessary. No prior experience with lattice is required to read the book, although basic familiarity with R is assumed. The book contains close to 150 figures produced with lattice. Many of the examples emphasize principles of good graphical design; almost all use real data sets that are publicly available in various R packages. All code and figures in the book are also available online, along with supplementary material covering more advanced topics. |
| data science and pharmacy: Remington Adeboye Adejare, 2020-11-03 The PCP's Bicentennial Edition Remington: The Science and Practice of Pharmacy, Twenty Third Edition, offers a trusted, completely updated source of information for education, training, and development of pharmacists. Published for the first time with Elsevier, this edition includes coverage of biologics and biosimilars as uses of those therapeutics have increased substantially since the previous edition. Also discussed are formulations, drug delivery (including prodrugs, salts, polymorphism. With clear, detailed color illustrations, fundamental information on a range of pharmaceutical science areas, and information on new developments in industry, pharmaceutical industry scientists, especially those involved in drug discovery and development will find this edition of Remington an essential reference. Intellectual property professionals will also find this reference helpful to cite in patents and resulting litigations. Additional graduate and postgraduate students in Pharmacy and Pharmaceutical Sciences will refer to this book in courses dealing with medicinal chemistry and pharmaceutics. - Contains a comprehensive source of principles of drug discovery and development topics, especially for scientists that are new in the pharmaceutical industry such as those with trainings/degrees in chemistry and engineering - Provides a detailed source for formulation scientists and compounding pharmacists, from produg to excipient issues - Updates this excellent source with the latest information to verify facts and refresh on basics for professionals in the broadly defined pharmaceutical industry |
| data science and pharmacy: Research Methods for Pharmaceutical Practice and Policy Rajender R. Aparasu, 2011 This text provides the theory and practice for conducting pharmaceutical policy research. It covers all aspects of scientific research from conceptualising to statistical analysis. It also provides scientific basis and a good understanding of the principles and practice of conducting pharmaceutical policy research. |
| data science and pharmacy: Contemporary Research Methods in Pharmacy and Health Services Shane P. Desselle, Victoria Garcia Cardenas, Claire Anderson, Parisa Aslani, Aleda M. H. Chen, Timothy F. Chen, 2022-05-10 Emerging methods, as well as best practices in well-used methods, in pharmacy are of great benefit to researchers, graduate students, graduate programs, residents and fellows also in other health science areas. Researchers require a text to assist in the design of experiments to address seemingly age-old problems. New interventions are needed to improve medication adherence, patients' lived experiences in health care, provider-patient relationships, and even various facets of pharmacogenomics. Advances in systems re-engineering can optimize health care practitioners' roles. Contemporary Research Methods in Pharmacy and Health Services includes multi-authored chapters by renowned experts in their field. Chapters cover examples in pharmacy, health services and others transcendent of medical care, following a standardized format, including key research points; valid and invalid assumptions; pitfalls to avoid; applications; and further inquiry. This is a valuable resource for researchers both in academia and corporate R&D, primarily in pharmacy but also in health services, and other health disciplines. Social science researchers and government scientists can also benefit from the reading. - Provides multi-authored chapters by renowned experts in their field - Includes examples for pharmacy and health services and others that are transcendent of medical care - Covers key research points, valid and invalid assumptions, pitfalls to avoid, applications, and further inquiry |
| data science and pharmacy: Bad Pharma Ben Goldacre, 2014-04 Originally published in 2012, revised edition published in 2013, by Fourth Estate, Great Britain; Published in the United States in 2012, revised edition also, by Faber and Faber, Inc. |
| data science and pharmacy: Beginning Data Science in R Thomas Mailund, 2017-03-09 Discover best practices for data analysis and software development in R and start on the path to becoming a fully-fledged data scientist. This book teaches you techniques for both data manipulation and visualization and shows you the best way for developing new software packages for R. Beginning Data Science in R details how data science is a combination of statistics, computational science, and machine learning. You’ll see how to efficiently structure and mine data to extract useful patterns and build mathematical models. This requires computational methods and programming, and R is an ideal programming language for this. This book is based on a number of lecture notes for classes the author has taught on data science and statistical programming using the R programming language. Modern data analysis requires computational skills and usually a minimum of programming. What You Will Learn Perform data science and analytics using statistics and the R programming language Visualize and explore data, including working with large data sets found in big data Build an R package Test and check your code Practice version control Profile and optimize your code Who This Book Is For Those with some data science or analytics background, but not necessarily experience with the R programming language. |
| data science and pharmacy: Fundamentals of Clinical Data Science Pieter Kubben, Michel Dumontier, Andre Dekker, 2018-12-21 This open access book comprehensively covers the fundamentals of clinical data science, focusing on data collection, modelling and clinical applications. Topics covered in the first section on data collection include: data sources, data at scale (big data), data stewardship (FAIR data) and related privacy concerns. Aspects of predictive modelling using techniques such as classification, regression or clustering, and prediction model validation will be covered in the second section. The third section covers aspects of (mobile) clinical decision support systems, operational excellence and value-based healthcare. Fundamentals of Clinical Data Science is an essential resource for healthcare professionals and IT consultants intending to develop and refine their skills in personalized medicine, using solutions based on large datasets from electronic health records or telemonitoring programmes. The book’s promise is “no math, no code”and will explain the topics in a style that is optimized for a healthcare audience. |
| data science and pharmacy: Statistics and Machine Learning Methods for EHR Data Hulin Wu, Jose Miguel Yamal, Ashraf Yaseen, Vahed Maroufy, 2020-12-09 The use of Electronic Health Records (EHR)/Electronic Medical Records (EMR) data is becoming more prevalent for research. However, analysis of this type of data has many unique complications due to how they are collected, processed and types of questions that can be answered. This book covers many important topics related to using EHR/EMR data for research including data extraction, cleaning, processing, analysis, inference, and predictions based on many years of practical experience of the authors. The book carefully evaluates and compares the standard statistical models and approaches with those of machine learning and deep learning methods and reports the unbiased comparison results for these methods in predicting clinical outcomes based on the EHR data. Key Features: Written based on hands-on experience of contributors from multidisciplinary EHR research projects, which include methods and approaches from statistics, computing, informatics, data science and clinical/epidemiological domains. Documents the detailed experience on EHR data extraction, cleaning and preparation Provides a broad view of statistical approaches and machine learning prediction models to deal with the challenges and limitations of EHR data. Considers the complete cycle of EHR data analysis. The use of EHR/EMR analysis requires close collaborations between statisticians, informaticians, data scientists and clinical/epidemiological investigators. This book reflects that multidisciplinary perspective. |
| data science and pharmacy: Healthcare Data Analytics and Management Nilanjan Dey, Amira S. Ashour, Simon James Fong, Chintan Bhatt, 2018-11-15 Healthcare Data Analytics and Management help readers disseminate cutting-edge research that delivers insights into the analytic tools, opportunities, novel strategies, techniques and challenges for handling big data, data analytics and management in healthcare. As the rapidly expanding and heterogeneous nature of healthcare data poses challenges for big data analytics, this book targets researchers and bioengineers from areas of machine learning, data mining, data management, and healthcare providers, along with clinical researchers and physicians who are interested in the management and analysis of healthcare data. - Covers data analysis, management and security concepts and tools in the healthcare domain - Highlights electronic medical health records and patient information records - Discusses the different techniques to integrate Big data and Internet-of-Things in healthcare, including machine learning and data mining - Includes multidisciplinary contributions in relation to healthcare applications and challenges |
| data science and pharmacy: The Essentials of Data Science: Knowledge Discovery Using R Graham J. Williams, 2017-07-28 The Essentials of Data Science: Knowledge Discovery Using R presents the concepts of data science through a hands-on approach using free and open source software. It systematically drives an accessible journey through data analysis and machine learning to discover and share knowledge from data. Building on over thirty years’ experience in teaching and practising data science, the author encourages a programming-by-example approach to ensure students and practitioners attune to the practise of data science while building their data skills. Proven frameworks are provided as reusable templates. Real world case studies then provide insight for the data scientist to swiftly adapt the templates to new tasks and datasets. The book begins by introducing data science. It then reviews R’s capabilities for analysing data by writing computer programs. These programs are developed and explained step by step. From analysing and visualising data, the framework moves on to tried and tested machine learning techniques for predictive modelling and knowledge discovery. Literate programming and a consistent style are a focus throughout the book. |
| data science and pharmacy: Demystifying Big Data and Machine Learning for Healthcare Prashant Natarajan, John C. Frenzel, Detlev H. Smaltz, 2017-02-15 Healthcare transformation requires us to continually look at new and better ways to manage insights – both within and outside the organization today. Increasingly, the ability to glean and operationalize new insights efficiently as a byproduct of an organization’s day-to-day operations is becoming vital to hospitals and health systems ability to survive and prosper. One of the long-standing challenges in healthcare informatics has been the ability to deal with the sheer variety and volume of disparate healthcare data and the increasing need to derive veracity and value out of it. Demystifying Big Data and Machine Learning for Healthcare investigates how healthcare organizations can leverage this tapestry of big data to discover new business value, use cases, and knowledge as well as how big data can be woven into pre-existing business intelligence and analytics efforts. This book focuses on teaching you how to: Develop skills needed to identify and demolish big-data myths Become an expert in separating hype from reality Understand the V’s that matter in healthcare and why Harmonize the 4 C’s across little and big data Choose data fi delity over data quality Learn how to apply the NRF Framework Master applied machine learning for healthcare Conduct a guided tour of learning algorithms Recognize and be prepared for the future of artificial intelligence in healthcare via best practices, feedback loops, and contextually intelligent agents (CIAs) The variety of data in healthcare spans multiple business workflows, formats (structured, un-, and semi-structured), integration at point of care/need, and integration with existing knowledge. In order to deal with these realities, the authors propose new approaches to creating a knowledge-driven learning organization-based on new and existing strategies, methods and technologies. This book will address the long-standing challenges in healthcare informatics and provide pragmatic recommendations on how to deal with them. |
| data science and pharmacy: Data Science at the Command Line Jeroen Janssens, 2014-09-25 This hands-on guide demonstrates how the flexibility of the command line can help you become a more efficient and productive data scientist. You’ll learn how to combine small, yet powerful, command-line tools to quickly obtain, scrub, explore, and model your data. To get you started—whether you’re on Windows, OS X, or Linux—author Jeroen Janssens introduces the Data Science Toolbox, an easy-to-install virtual environment packed with over 80 command-line tools. Discover why the command line is an agile, scalable, and extensible technology. Even if you’re already comfortable processing data with, say, Python or R, you’ll greatly improve your data science workflow by also leveraging the power of the command line. Obtain data from websites, APIs, databases, and spreadsheets Perform scrub operations on plain text, CSV, HTML/XML, and JSON Explore data, compute descriptive statistics, and create visualizations Manage your data science workflow using Drake Create reusable tools from one-liners and existing Python or R code Parallelize and distribute data-intensive pipelines using GNU Parallel Model data with dimensionality reduction, clustering, regression, and classification algorithms |
| data science and pharmacy: Programming Skills For Data Science Freeman, Programming Skills for Data Science brings together all the foundation skills needed to transform raw data into actionable insights for domains ranging from urban planning to precision medicine, even if you have no programming or data science experience. Guided by expert instructors Michael Freeman and Joel Ross, this book will help learners install the tools required to solve professional-level data science problems, including widely used R language, RStudio integrated development environment, and Git version-control system. It explains how to wrangle data into a form where it can be easily used, analyzed, and visualized so others can see the patterns uncovered. Step by step, students will master powerful R programming techniques and troubleshooting skills for probing data in new ways, and at larger scales. |
| data science and pharmacy: Algorithms for Data Science Brian Steele, John Chandler, Swarna Reddy, 2016-12-25 This textbook on practical data analytics unites fundamental principles, algorithms, and data. Algorithms are the keystone of data analytics and the focal point of this textbook. Clear and intuitive explanations of the mathematical and statistical foundations make the algorithms transparent. But practical data analytics requires more than just the foundations. Problems and data are enormously variable and only the most elementary of algorithms can be used without modification. Programming fluency and experience with real and challenging data is indispensable and so the reader is immersed in Python and R and real data analysis. By the end of the book, the reader will have gained the ability to adapt algorithms to new problems and carry out innovative analyses. This book has three parts:(a) Data Reduction: Begins with the concepts of data reduction, data maps, and information extraction. The second chapter introduces associative statistics, the mathematical foundation of scalable algorithms and distributed computing. Practical aspects of distributed computing is the subject of the Hadoop and MapReduce chapter.(b) Extracting Information from Data: Linear regression and data visualization are the principal topics of Part II. The authors dedicate a chapter to the critical domain of Healthcare Analytics for an extended example of practical data analytics. The algorithms and analytics will be of much interest to practitioners interested in utilizing the large and unwieldly data sets of the Centers for Disease Control and Prevention's Behavioral Risk Factor Surveillance System.(c) Predictive Analytics Two foundational and widely used algorithms, k-nearest neighbors and naive Bayes, are developed in detail. A chapter is dedicated to forecasting. The last chapter focuses on streaming data and uses publicly accessible data streams originating from the Twitter API and the NASDAQ stock market in the tutorials. This book is intended for a one- or two-semester course in data analytics for upper-division undergraduate and graduate students in mathematics, statistics, and computer science. The prerequisites are kept low, and students with one or two courses in probability or statistics, an exposure to vectors and matrices, and a programming course will have no difficulty. The core material of every chapter is accessible to all with these prerequisites. The chapters often expand at the close with innovations of interest to practitioners of data science. Each chapter includes exercises of varying levels of difficulty. The text is eminently suitable for self-study and an exceptional resource for practitioners. |
| data science and pharmacy: Data Science in Chemistry Thorsten Gressling, 2020-11-23 The ever-growing wealth of information has led to the emergence of a fourth paradigm of science. This new field of activity – data science – includes computer science, mathematics and a given specialist domain. This book focuses on chemistry, explaining how to use data science for deep insights and take chemical research and engineering to the next level. It covers modern aspects like Big Data, Artificial Intelligence and Quantum computing. |
| data science and pharmacy: Research and Development in the Pharmaceutical Industry (A CBO Study) Congressional Budget Office, 2013-06-09 Perceptions that the pace of new-drug development has slowed and that the pharmaceutical industry is highly profitable have sparked concerns that significant problems loom for future drug development. This Congressional Budget Office (CBO) study-prepared at the request of the Senate Majority Leader-reviews basic facts about the drug industry's recent spending on research and development (R&D) and its output of new drugs. The study also examines issues relating to the costs of R&D, the federal government's role in pharmaceutical research, the performance of the pharmaceutical industry in developing innovative drugs, and the role of expected profits in private firms' decisions about investing in drug R&D. In keeping with CBO's mandate to provide objective, impartial analysis, the study makes no recommendations. David H. Austin prepared this report under the supervision of Joseph Kile and David Moore. Colin Baker provided valuable consultation... |
| data science and pharmacy: Clinical Pharmacy Education, Practice and Research Dixon Thomas, 2018-11-23 Clinical Pharmacy Education, Practice and Research offers readers a solid foundation in clinical pharmacy and related sciences through contributions by 83 leading experts in the field from 25 countries. This book stresses educational approaches that empower pharmacists with patient care and research competencies. The learning objectives and writing style of the book focus on clarifying the concepts comprehensively for a pharmacist, from regular patient counseling to pharmacogenomics practice. It covers all interesting topics a pharmacist should know. This book serves as a basis to standardize and coordinate learning to practice, explaining basics and using self-learning strategies through online resources or other advanced texts. With an educational approach, it guides pharmacy students and pharmacists to learn quickly and apply. Clinical Pharmacy Education, Practice and Research provides an essential foundation for pharmacy students and pharmacists globally. - Covers the core information needed for pharmacy practice courses - Includes multiple case studies and practical situations with 70% focused on practical clinical pharmacology knowledge - Designed for educational settings, but also useful as a refresher for advanced students and researchers |
| data science and pharmacy: The Pharmacy Informatics Primer Doina Dumitru, 2008-09-30 The information technology revolution has fueled the demand in hospitals and health systems for accomplished experts who can help select, implement and maintain CPOE, BCMA, EHR and other systems. As the use of IT in healthcare expands and the complexity of medication therapy increases, there has been a correspondingly rapid growth in the practice of pharmacy informatics and a basic need for an understanding of key elements. The Pharmacy Informatics Primer provides a foundational understanding and offers “pearls of wisdom” for pharmacy professionals involved in informatics. This introductory resource outlines key concepts in understanding, developing, implementing, and maintaining clinical information and automation systems. This essential guide is designed for all pharmacists and covers an introduction to major concepts of informatics such as ePrescribing, CPOE, bar-coding, smart pumps, and the pharmacist’s role in EHR. Chapter features include key terms and definitions, and a comprehensive table of pearls, specific to each subject to present a clear understanding of all concepts. |
| data science and pharmacy: Big Data, Big Challenges: A Healthcare Perspective Mowafa Househ, Andre W. Kushniruk, Elizabeth M. Borycki, 2019-02-26 This is the first book to offer a comprehensive yet concise overview of the challenges and opportunities presented by the use of big data in healthcare. The respective chapters address a range of aspects: from health management to patient safety; from the human factor perspective to ethical and economic considerations, and many more. By providing a historical background on the use of big data, and critically analyzing current approaches together with issues and challenges related to their applications, the book not only sheds light on the problems entailed by big data, but also paves the way for possible solutions and future research directions. Accordingly, it offers an insightful reference guide for health information technology professionals, healthcare managers, healthcare practitioners, and patients alike, aiding them in their decision-making processes; and for students and researchers whose work involves data science-related research issues in healthcare. |
| data science and pharmacy: Advanced Data Science and Analytics with Python Jesus Rogel-Salazar, 2020-05-05 Advanced Data Science and Analytics with Python enables data scientists to continue developing their skills and apply them in business as well as academic settings. The subjects discussed in this book are complementary and a follow-up to the topics discussed in Data Science and Analytics with Python. The aim is to cover important advanced areas in data science using tools developed in Python such as SciKit-learn, Pandas, Numpy, Beautiful Soup, NLTK, NetworkX and others. The model development is supported by the use of frameworks such as Keras, TensorFlow and Core ML, as well as Swift for the development of iOS and MacOS applications. Features: Targets readers with a background in programming, who are interested in the tools used in data analytics and data science Uses Python throughout Presents tools, alongside solved examples, with steps that the reader can easily reproduce and adapt to their needs Focuses on the practical use of the tools rather than on lengthy explanations Provides the reader with the opportunity to use the book whenever needed rather than following a sequential path The book can be read independently from the previous volume and each of the chapters in this volume is sufficiently independent from the others, providing flexibility for the reader. Each of the topics addressed in the book tackles the data science workflow from a practical perspective, concentrating on the process and results obtained. The implementation and deployment of trained models are central to the book. Time series analysis, natural language processing, topic modelling, social network analysis, neural networks and deep learning are comprehensively covered. The book discusses the need to develop data products and addresses the subject of bringing models to their intended audiences – in this case, literally to the users’ fingertips in the form of an iPhone app. About the Author Dr. Jesús Rogel-Salazar is a lead data scientist in the field, working for companies such as Tympa Health Technologies, Barclays, AKQA, IBM Data Science Studio and Dow Jones. He is a visiting researcher at the Department of Physics at Imperial College London, UK and a member of the School of Physics, Astronomy and Mathematics at the University of Hertfordshire, UK. |
| data science and pharmacy: An Introduction to Pharmaceutical Sciences Jiben Roy, 2011-07-25 This textbook is written as a unified approach to various topics, ranging from drug discovery to manufacturing, techniques and technology, regulation and marketing. The key theme of the book is pharmaceuticals - what every student of pharmaceutical sciences should know: from the active pharmaceutical ingredients to the preparation of various dosage forms along with the relevant chemistry, this book makes pharmaceuticals relevant to undergraduate students of pharmacy and pharmaceutical sciences.This book explains how a particular drug was discovered and then converted from lab-scale to manufacturing scale, to the market. It explains the motivation for drug discovery, the reaction chemistry involved, experimental difficulties, various dosage forms and the reasoning behind them, mechanism of action, quality assurance and role of regulatory agencies. After having a course based on this book, the student will be able to understand: 1) the career prospects in the pharmaceutical industry, 2) the need for interdisciplinary teamwork in science, 3) the techniques and technology involved in making pharmaceuticals starting from bulk drugs, and 4) different dosage forms and critical factors in the development of pharmaceutical formulations in relation to the principles of chemistry.A few blockbuster drugs including atorvastatin, sildanefil, ranitidine, ciprofloxacin, amoxicillin, and the longest serving drugs such as aspirin and paracetamol are discussed in detail. Finally, the book also covers the important current pharmaceutical issues like quality control, safety, counterfeiting and abuse of drugs, and future prospects for pharmaceutical industry. - Unified approach explaining drug discovery, bulk drug manufacturing, formulation of dosage forms, with pharmacological and therapeutic actions - Manufacturing processes of representative active pharmaceutical ingredients and their chemistry plus formulation of dosage forms presented in this book are based on actual industrial processes - Covers many aspects relevant to students of the pharmaceutical sciences or newly employed pharmaceutical researchers/employees. It contains summary information about regulatory agencies of different countries |
| data science and pharmacy: Data Science For Dummies Lillian Pierson, 2021-08-20 Monetize your company’s data and data science expertise without spending a fortune on hiring independent strategy consultants to help What if there was one simple, clear process for ensuring that all your company’s data science projects achieve a high a return on investment? What if you could validate your ideas for future data science projects, and select the one idea that’s most prime for achieving profitability while also moving your company closer to its business vision? There is. Industry-acclaimed data science consultant, Lillian Pierson, shares her proprietary STAR Framework – A simple, proven process for leading profit-forming data science projects. Not sure what data science is yet? Don’t worry! Parts 1 and 2 of Data Science For Dummies will get all the bases covered for you. And if you’re already a data science expert? Then you really won’t want to miss the data science strategy and data monetization gems that are shared in Part 3 onward throughout this book. Data Science For Dummies demonstrates: The only process you’ll ever need to lead profitable data science projects Secret, reverse-engineered data monetization tactics that no one’s talking about The shocking truth about how simple natural language processing can be How to beat the crowd of data professionals by cultivating your own unique blend of data science expertise Whether you’re new to the data science field or already a decade in, you’re sure to learn something new and incredibly valuable from Data Science For Dummies. Discover how to generate massive business wins from your company’s data by picking up your copy today. |
| data science and pharmacy: Data Science Projects with Python Stephen Klosterman, 2019-04-30 Gain hands-on experience with industry-standard data analysis and machine learning tools in Python Key FeaturesTackle data science problems by identifying the problem to be solvedIllustrate patterns in data using appropriate visualizationsImplement suitable machine learning algorithms to gain insights from dataBook Description Data Science Projects with Python is designed to give you practical guidance on industry-standard data analysis and machine learning tools, by applying them to realistic data problems. You will learn how to use pandas and Matplotlib to critically examine datasets with summary statistics and graphs, and extract the insights you seek to derive. You will build your knowledge as you prepare data using the scikit-learn package and feed it to machine learning algorithms such as regularized logistic regression and random forest. You’ll discover how to tune algorithms to provide the most accurate predictions on new and unseen data. As you progress, you’ll gain insights into the working and output of these algorithms, building your understanding of both the predictive capabilities of the models and why they make these predictions. By then end of this book, you will have the necessary skills to confidently use machine learning algorithms to perform detailed data analysis and extract meaningful insights from unstructured data. What you will learnInstall the required packages to set up a data science coding environmentLoad data into a Jupyter notebook running PythonUse Matplotlib to create data visualizationsFit machine learning models using scikit-learnUse lasso and ridge regression to regularize your modelsCompare performance between models to find the best outcomesUse k-fold cross-validation to select model hyperparametersWho this book is for If you are a data analyst, data scientist, or business analyst who wants to get started using Python and machine learning techniques to analyze data and predict outcomes, this book is for you. Basic knowledge of Python and data analytics will help you get the most from this book. Familiarity with mathematical concepts such as algebra and basic statistics will also be useful. |
| data science and pharmacy: Pharmaceutical Analysis E-Book David G. Watson, 2015-12-24 Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of chemical, physical and microbiological analyses. It is reckoned that over £10 billion is spent annually in the UK alone on pharmaceutical analysis, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals. This is the key textbook in pharmaceutical analysis, now revised and updated for its fourth edition. Worked calculation examples Self-assessment Additional problems (self tests) Practical boxes Key points boxes New chapter on electrochemical biosensors. New chapter on the quality control of biotechnologically produced drugs. Extended chapter on molecular emission spectroscopy. Now comes with an e-book on StudentConsult. Self-assessment is interactive in the accompanying online e-book. 65 online animations show concepts such as ionization partitioning of drug molecules etc. ~ |
| data science and pharmacy: Doing Data Science Cathy O'Neil, Rachel Schutt, 2013-10-09 Now that people are aware that data can make the difference in an election or a business model, data science as an occupation is gaining ground. But how can you get started working in a wide-ranging, interdisciplinary field that’s so clouded in hype? This insightful book, based on Columbia University’s Introduction to Data Science class, tells you what you need to know. In many of these chapter-long lectures, data scientists from companies such as Google, Microsoft, and eBay share new algorithms, methods, and models by presenting case studies and the code they use. If you’re familiar with linear algebra, probability, and statistics, and have programming experience, this book is an ideal introduction to data science. Topics include: Statistical inference, exploratory data analysis, and the data science process Algorithms Spam filters, Naive Bayes, and data wrangling Logistic regression Financial modeling Recommendation engines and causality Data visualization Social networks and data journalism Data engineering, MapReduce, Pregel, and Hadoop Doing Data Science is collaboration between course instructor Rachel Schutt, Senior VP of Data Science at News Corp, and data science consultant Cathy O’Neil, a senior data scientist at Johnson Research Labs, who attended and blogged about the course. |
| data science and pharmacy: Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications, Third Edition Johan Gabrielsson, Daniel Weiner, 2001-11-30 This is a revised and very expanded version of the previous second edition of the book. Pharmacokinetic and Pharmacodynamic Data Analysis provides an introduction into pharmacokinetic and pharmacodynamic concepts using simple illustrations and reasoning. It describes ways in which pharmacodynamic and pharmacodynamic theory may be used to give insight into modeling questions and how these questions can in turn lead to new knowledge. This book differentiates itself from other texts in this area in that it bridges the gap between relevant theory and the actual application of the theory to real life situations. The book is divided into two parts; the first introduces fundamental principles of PK and PD concepts, and principles of mathematical modeling, while the second provides case studies obtained from drug industry and academia. Topics included in the first part include a discussion of the statistical principles of model fitting, including how to assess the adequacy of the fit of a model, as well as strategies for selection of time points to be included in the design of a study. The first part also introduces basic pharmacokinetic and pharmacodynamic concepts, including an excellent discussion of effect compartment (link) models as well as indirect response models. The second part of the text includes over 70 modeling case studies. These include a discussion of the selection of the model, derivation of initial parameter estimates and interpretation of the corresponding output. Finally, the authors discuss a number of pharmacodynamic modeling situations including receptor binding models, synergy, and tolerance models (feedback and precursor models). This book will be of interest to researchers, to graduate students and advanced undergraduate students in the PK/PD area who wish to learn how to analyze biological data and build models and to become familiar with new areas of application. In addition, the text will be of interest to toxicologists interested in learning about determinants of exposure and performing toxicokinetic modeling. The inclusion of the numerous exercises and models makes it an excellent primary or adjutant text for traditional PK courses taught in pharmacy and medical schools. A diskette is included with the text that includes all of the exercises and solutions using WinNonlin. |
| data science and pharmacy: The Data Science Design Manual Steven S. Skiena, 2017-07-01 This engaging and clearly written textbook/reference provides a must-have introduction to the rapidly emerging interdisciplinary field of data science. It focuses on the principles fundamental to becoming a good data scientist and the key skills needed to build systems for collecting, analyzing, and interpreting data. The Data Science Design Manual is a source of practical insights that highlights what really matters in analyzing data, and provides an intuitive understanding of how these core concepts can be used. The book does not emphasize any particular programming language or suite of data-analysis tools, focusing instead on high-level discussion of important design principles. This easy-to-read text ideally serves the needs of undergraduate and early graduate students embarking on an “Introduction to Data Science” course. It reveals how this discipline sits at the intersection of statistics, computer science, and machine learning, with a distinct heft and character of its own. Practitioners in these and related fields will find this book perfect for self-study as well. Additional learning tools: Contains “War Stories,” offering perspectives on how data science applies in the real world Includes “Homework Problems,” providing a wide range of exercises and projects for self-study Provides a complete set of lecture slides and online video lectures at www.data-manual.com Provides “Take-Home Lessons,” emphasizing the big-picture concepts to learn from each chapter Recommends exciting “Kaggle Challenges” from the online platform Kaggle Highlights “False Starts,” revealing the subtle reasons why certain approaches fail Offers examples taken from the data science television show “The Quant Shop” (www.quant-shop.com) |
| data science and pharmacy: Introducing Data Science Davy Cielen, Arno Meysman, 2016-05-02 Summary Introducing Data Science teaches you how to accomplish the fundamental tasks that occupy data scientists. Using the Python language and common Python libraries, you'll experience firsthand the challenges of dealing with data at scale and gain a solid foundation in data science. Purchase of the print book includes a free eBook in PDF, Kindle, and ePub formats from Manning Publications. About the Technology Many companies need developers with data science skills to work on projects ranging from social media marketing to machine learning. Discovering what you need to learn to begin a career as a data scientist can seem bewildering. This book is designed to help you get started. About the Book Introducing Data ScienceIntroducing Data Science explains vital data science concepts and teaches you how to accomplish the fundamental tasks that occupy data scientists. You’ll explore data visualization, graph databases, the use of NoSQL, and the data science process. You’ll use the Python language and common Python libraries as you experience firsthand the challenges of dealing with data at scale. Discover how Python allows you to gain insights from data sets so big that they need to be stored on multiple machines, or from data moving so quickly that no single machine can handle it. This book gives you hands-on experience with the most popular Python data science libraries, Scikit-learn and StatsModels. After reading this book, you’ll have the solid foundation you need to start a career in data science. What’s Inside Handling large data Introduction to machine learning Using Python to work with data Writing data science algorithms About the Reader This book assumes you're comfortable reading code in Python or a similar language, such as C, Ruby, or JavaScript. No prior experience with data science is required. About the Authors Davy Cielen, Arno D. B. Meysman, and Mohamed Ali are the founders and managing partners of Optimately and Maiton, where they focus on developing data science projects and solutions in various sectors. Table of Contents Data science in a big data world The data science process Machine learning Handling large data on a single computer First steps in big data Join the NoSQL movement The rise of graph databases Text mining and text analytics Data visualization to the end user |
| data science and pharmacy: GAMP 5 Sion Wyn, 2008 GAMP 5 provides pragmatic and practical industry guidance to achieve compliant computerized systems fit for intended use in an efficient and effective manner. This technical document describes a flexible risk-based approach to compliant GxP regulated computerized systems, based on scalable specification and verification. It points to the future of computer systems compliance by centering on principles behind major industry developments such as PQLI; ICH Q8, Q9, Q10; and ASTM E2500. This revolutionary Guide addresses the entire lifecycle of an automated system and its applicability to a wide range of information systems, lab equipment, integrated manufacturing systems, and IT infrastructures. It contains new information on outsourcing, electronic batch recording, end user applications (such as spreadsheets and small database applications), and patch management. |
| data science and pharmacy: Accelerated Predictive Stability (APS) Fenghe Qiu, Garry Scrivens, 2018-05-14 Accelerated Predictive Stability (APS): Fundamentals and Pharmaceutical Industry Practices provides coverage of both the fundamental principles and pharmaceutical industry applications of the APS approach. Fundamental chapters explain the scientific basis of the APS approach, while case study chapters from many innovative pharmaceutical companies provide a thorough overview of the current status of APS applications in the pharmaceutical industry. In addition, up-to-date experiences in utilizing APS data for regulatory submissions in many regions and countries highlight the potential of APS in support of registration stability testing for certain regulatory submissions. This book provides high level strategies for the successful implementation of APS in a pharmaceutical company. It offers scientists and regulators a comprehensive resource on how the pharmaceutical industry can enhance their understanding of a product's stability and predict drug expiry more accurately and quickly. - Provides a comprehensive, one-stop-shop resource for accelerated predictive stability (APS) - Presents the scientific basis of different APS models - Includes the applications and utilities of APS that are demonstrated through numerous case studies - Covers up-to-date regulatory experience |
| data science and pharmacy: Artificial Intelligence in Drug Discovery Nathan Brown, 2020-11-04 Following significant advances in deep learning and related areas interest in artificial intelligence (AI) has rapidly grown. In particular, the application of AI in drug discovery provides an opportunity to tackle challenges that previously have been difficult to solve, such as predicting properties, designing molecules and optimising synthetic routes. Artificial Intelligence in Drug Discovery aims to introduce the reader to AI and machine learning tools and techniques, and to outline specific challenges including designing new molecular structures, synthesis planning and simulation. Providing a wealth of information from leading experts in the field this book is ideal for students, postgraduates and established researchers in both industry and academia. |
| data science and pharmacy: Data Science from Scratch Joel Grus, 2015-04-14 Data science libraries, frameworks, modules, and toolkits are great for doing data science, but they’re also a good way to dive into the discipline without actually understanding data science. In this book, you’ll learn how many of the most fundamental data science tools and algorithms work by implementing them from scratch. If you have an aptitude for mathematics and some programming skills, author Joel Grus will help you get comfortable with the math and statistics at the core of data science, and with hacking skills you need to get started as a data scientist. Today’s messy glut of data holds answers to questions no one’s even thought to ask. This book provides you with the know-how to dig those answers out. Get a crash course in Python Learn the basics of linear algebra, statistics, and probability—and understand how and when they're used in data science Collect, explore, clean, munge, and manipulate data Dive into the fundamentals of machine learning Implement models such as k-nearest Neighbors, Naive Bayes, linear and logistic regression, decision trees, neural networks, and clustering Explore recommender systems, natural language processing, network analysis, MapReduce, and databases |
| data science and pharmacy: Getting Started with Data Science Murtaza Haider, 2015-12-14 Master Data Analytics Hands-On by Solving Fascinating Problems You’ll Actually Enjoy! Harvard Business Review recently called data science “The Sexiest Job of the 21st Century.” It’s not just sexy: For millions of managers, analysts, and students who need to solve real business problems, it’s indispensable. Unfortunately, there’s been nothing easy about learning data science–until now. Getting Started with Data Science takes its inspiration from worldwide best-sellers like Freakonomics and Malcolm Gladwell’s Outliers: It teaches through a powerful narrative packed with unforgettable stories. Murtaza Haider offers informative, jargon-free coverage of basic theory and technique, backed with plenty of vivid examples and hands-on practice opportunities. Everything’s software and platform agnostic, so you can learn data science whether you work with R, Stata, SPSS, or SAS. Best of all, Haider teaches a crucial skillset most data science books ignore: how to tell powerful stories using graphics and tables. Every chapter is built around real research challenges, so you’ll always know why you’re doing what you’re doing. You’ll master data science by answering fascinating questions, such as: • Are religious individuals more or less likely to have extramarital affairs? • Do attractive professors get better teaching evaluations? • Does the higher price of cigarettes deter smoking? • What determines housing prices more: lot size or the number of bedrooms? • How do teenagers and older people differ in the way they use social media? • Who is more likely to use online dating services? • Why do some purchase iPhones and others Blackberry devices? • Does the presence of children influence a family’s spending on alcohol? For each problem, you’ll walk through defining your question and the answers you’ll need; exploring how others have approached similar challenges; selecting your data and methods; generating your statistics; organizing your report; and telling your story. Throughout, the focus is squarely on what matters most: transforming data into insights that are clear, accurate, and can be acted upon. |
| data science and pharmacy: Business Intelligence Demystified Anoop Kumar V K, 2021-09-25 Clear your doubts about Business Intelligence and start your new journey KEY FEATURES ● Includes successful methods and innovative ideas to achieve success with BI. ● Vendor-neutral, unbiased, and based on experience. ● Highlights practical challenges in BI journeys. ● Covers financial aspects along with technical aspects. ● Showcases multiple BI organization models and the structure of BI teams. DESCRIPTION The book demystifies misconceptions and misinformation about BI. It provides clarity to almost everything related to BI in a simplified and unbiased way. It covers topics right from the definition of BI, terms used in the BI definition, coinage of BI, details of the different main uses of BI, processes that support the main uses, side benefits, and the level of importance of BI, various types of BI based on various parameters, main phases in the BI journey and the challenges faced in each of the phases in the BI journey. It clarifies myths about self-service BI and real-time BI. The book covers the structure of a typical internal BI team, BI organizational models, and the main roles in BI. It also clarifies the doubts around roles in BI. It explores the different components that add to the cost of BI and explains how to calculate the total cost of the ownership of BI and ROI for BI. It covers several ideas, including unconventional ideas to achieve BI success and also learn about IBI. It explains the different types of BI architectures, commonly used technologies, tools, and concepts in BI and provides clarity about the boundary of BI w.r.t technologies, tools, and concepts. The book helps you lay a very strong foundation and provides the right perspective about BI. It enables you to start or restart your journey with BI. WHAT YOU WILL LEARN ● Builds a strong conceptual foundation in BI. ● Gives the right perspective and clarity on BI uses, challenges, and architectures. ● Enables you to make the right decisions on the BI structure, organization model, and budget. ● Explains which type of BI solution is required for your business. ● Applies successful BI ideas. WHO THIS BOOK IS FOR This book is a must-read for business managers, BI aspirants, CxOs, and all those who want to drive the business value with data-driven insights. TABLE OF CONTENTS 1. What is Business Intelligence? 2. Why do Businesses need BI? 3. Types of Business Intelligence 4. Challenges in Business Intelligence 5. Roles in Business Intelligence 6. Financials of Business Intelligence 7. Ideas for Success with BI 8. Introduction to IBI 9. BI Architectures 10. Demystify Tech, Tools, and Concepts in BI |
Data and Digital Outputs Management Plan (DDOMP)
Data and Digital Outputs Management Plan (DDOMP)
Building New Tools for Data Sharing and Reuse through a T…
Jan 10, 2019 · The SEI CRA will closely link research thinking and technological innovation toward accelerating the full …
Open Data Policy and Principles - Belmont Forum
The data policy includes the following principles: Data should be: Discoverable through catalogues and search …
Belmont Forum Adopts Open Data Principles for Environment…
Jan 27, 2016 · Adoption of the open data policy and principles is one of five recommendations in A Place to Stand: …
Belmont Forum Data Accessibility Statement and …
The DAS encourages researchers to plan for the longevity, reusability, and stability of the data attached to their research …
Data and Digital Outputs Management Plan (DDOMP)
Data and Digital Outputs Management Plan (DDOMP)
Building New Tools for Data Sharing and Reuse through a …
Jan 10, 2019 · The SEI CRA will closely link research thinking and technological innovation toward accelerating the full path of discovery-driven data use and open science. This will enable a …
Open Data Policy and Principles - Belmont Forum
The data policy includes the following principles: Data should be: Discoverable through catalogues and search engines; Accessible as open data by default, and made available with …
Belmont Forum Adopts Open Data Principles for Environmental …
Jan 27, 2016 · Adoption of the open data policy and principles is one of five recommendations in A Place to Stand: e-Infrastructures and Data Management for Global Change Research, …
Belmont Forum Data Accessibility Statement and Policy
The DAS encourages researchers to plan for the longevity, reusability, and stability of the data attached to their research publications and results. Access to data promotes reproducibility, …
Climate-Induced Migration in Africa and Beyond: Big Data and …
CLIMB will also leverage earth observation and social media data, and combine them with survey and official statistical data. This holistic approach will allow us to analyze migration process …
Advancing Resilience in Low Income Housing Using Climate …
Jun 4, 2020 · Environmental sustainability and public health considerations will be included. Machine Learning and Big Data Analytics will be used to identify optimal disaster resilient …
Belmont Forum
What is the Belmont Forum? The Belmont Forum is an international partnership that mobilizes funding of environmental change research and accelerates its delivery to remove critical …
Waterproofing Data: Engaging Stakeholders in Sustainable Flood …
Apr 26, 2018 · Waterproofing Data investigates the governance of water-related risks, with a focus on social and cultural aspects of data practices. Typically, data flows up from local levels to …
Data Management Annex (Version 1.4) - Belmont Forum
A full Data Management Plan (DMP) for an awarded Belmont Forum CRA project is a living, actively updated document that describes the data management life cycle for the data to be …
