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define physiological dependence: Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence World Health Organization. Department of Mental Health and Substance Abuse, World Health Organization, 2009 These guidelines were produced by the World Health Organization (WHO), Department of Mental Health and Substance Abuse, in collaboration with the United Nations Office on Drugs and Crime (UNODC) a Guidelines Development Group of technical experts, and in consultation with the International Narcotics Control Board (INCB) secretariat and other WHO departments. WHO also wishes to acknowledge the financial contribution of UNODC and the Joint United Nations Programme on HIV/AIDS (UNAIDS) to this project. - p. iv |
define physiological dependence: Neuropathology of Drug Addictions and Substance Misuse Volume 1 Victor R Preedy, 2016-03-07 Neuropathology of Drug Addictions and Substance Misuse, Volume One: Foundations of Understanding, Tobacco, Alcohol, Cannabinoids, Opioids and Emerging Addictions provides the latest research in an area that shows that the neuropathological features of one addiction are often applicable to those of others. The book also details how a further understanding of these commonalties can provide a platform for the study of specific addictions in greater depth, all in an effort to create new modes of understanding, causation, prevention, and treatment. The three volumes in this series address new research and challenges, offering comprehensive coverage on the adverse consequences of the most common drugs of abuse, with each volume serving to update the reader's knowledge on the broader field of addiction, while also deepening our understanding of specific addictive substances. Volume One addresses tobacco, alcohol, cannabinoids, and opioids, with each section providing data on the general, molecular/cellular, and structural/functional neurological aspects of a given substance, along with a focus on the adverse consequences of addictions. - Provides a modern approach on the pathology of substances of abuse, offering an evidence based ethos for understanding the neurology of addictions - Fills an existing gap in the literature by proving a one-stop-shopping synopsis of everything to do with the neuropathology of drugs of addiction and substance misuse - Includes a list of abbreviations, abstracts, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, and full references in each chapter - Offers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and the genome to whole body |
define physiological dependence: Substance and Non-substance Addiction Xiaochu Zhang, Jie Shi, Ran Tao, 2017-11-02 This book focuses on the similarities and differences between substance and non-substance addictions. It discusses in detail the mechanisms, diagnosis and treatment of substance and non-substance addictions, and addresses selected prospects that will shape future studies on addiction. Addiction is a global problem that costs millions of lives tremendous damage year after year. There are mainly two types of addition: substance addiction (e.g., nicotine, alcohol, cannabis, heroin, stimulants, etc.) and non-substance addiction (e.g., gambling, computer gaming, Internet, etc.). Based on existing evidence, both types of addiction produce negative impacts on individuals’ physical, mental, social and financial well-being, and share certain common mechanisms, which involve a dysfunction of the neural reward system and specific gene transcription factors. However, there are also key differences between these two types of addiction. Covering these aspects systematically, the book will provide researchers and graduate students alike a better understanding of drug and behavioral addictions. |
define physiological dependence: Theory of Addiction Robert West, Jamie Brown, 2013-11-04 The word ‘addiction’ these days is used to refer to a chronic condition where there is an unhealthily powerful motivation to engage in a particular behaviour. This can be driven by many different factors – physiological, psychological, environmental and social. If we say that it is all about X, we miss V, W, Y and Z. So, some people think addicts are using drugs to escape from unhappy lives, feelings of anxiety and so on; many are. Some people think drugs become addictive because they alter the brain chemistry to create powerful urges; that is often true. Others think that drug taking is about seeking after pleasure; often it is. Some take the view that addiction is a choice – addicts weigh up the pros and cons of doing what they do and decide the former outweigh the latter. Yet others believe that addicts suffer from poor impulse control; that is often true… And so it goes on. When you look at the evidence, you see that all these positions capture important aspects of the problem – but they are not complete explanations. Neuroscience can help us delve more deeply into some of these explanations, while the behavioural and social sciences are better at exploring others. We need a model that puts all this together in a way that can help us decide what to do in different cases. Should we prescribe a drug, give the person some ‘tender loving care’, put them in prison or what? Theory of Addiction provides this synthesis. The first edition was well received: ‘Throughout the book the reader is exposed to a vast number of useful observations...The theoretical aims are timely, refreshing, ambitious and above all challenging. It opens up a new way of looking at addiction and has the potential to move the field of addiction a considerable leap forward. Thus we wholeheartedly would like to recommend the book for students as well as scholars. Read and learn!’ Nordic Studies on Alcohol and Drugs ‘The book provides a comprehensive review of existing theories - over 30 in all - and this synthesis of theories constitutes an important contribution in and of itself... West is to be commended for his synthesis of addiction theories that span neurobiology, psychology and social science and for his insights into what remains unexplained.’ Addiction This new edition of Theory of Addiction builds on the first, including additional theories in the field, a more developed specification of PRIME theory and analysis of the expanding evidence base. With this important new information, Theory of Addiction will continue to be essential reading for all those working in addiction, from student to experienced practitioner – as urged above, Read and learn! |
define physiological dependence: Drugs, Brains, and Behavior , 2007 |
define physiological dependence: How Tobacco Smoke Causes Disease United States. Public Health Service. Office of the Surgeon General, 2010 This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products. |
define physiological dependence: Addiction and Change, First Edition Carlo C. DiClemente, 2003-04-02 The stages-of-change model has become widely known as a framework for conceptualizing recovery. Less well known are the processes that drive movement through the stages or how the stages apply to becoming addicted. From Carlo C. DiClemente, codeveloper of the transtheoretical model, this book offers a panoramic view of the entire continuum of addictive behavior change. The author illuminates the common path that individuals travel as they establish and reinforce new patterns of behavior, whether they are developing an addiction or struggling to free themselves from one, and regardless of the specific addictive behavior. The book addresses crucial questions of why, when, and how to intervene to bolster recovery in those already addicted and reach out effectively to people at risk. |
define physiological dependence: Clinical Addiction Psychiatry David Brizer, Ricardo Castaneda, 2010-09-16 Clinical Addiction Psychiatry is an anthology of essays that represent the most current and authoritative information now available on addiction theory, practice and research, covering dozens of provocative, fascinating and essential subdomains of the field. Each chapter is authored by a recognized authority in the field and detailed attention is paid to environment, genetics, culture and spirituality as well as treatment and pharmacology. History, street culture, and medical science are brought together in masterful discussions that encompass the full spectrum of addictive disorders, emphasizing assessment and clinical management. This unique resource gathers complex medical and scientific data in a way which is accessible to both health care professionals and readers without medical or psychology backgrounds. Essential reading for addiction counselors and other mental health professionals, this book will also be of interest to patients and their families, and residents and physicians in all fields of medicine. |
define physiological dependence: Textbook of Post-ICU Medicine Robert D. Stevens, Nicholas Hart, Margaret S. Herridge, 2014 Surviving critical illness is not always the happy ending that we imagine for patients. Intensive care unit (ICU) teams have traditionally focused on short term goals such as stabilizing or reversing organ system dysfunction, with little understanding of what became of patients once they left the ICU. However, research conducted in recent years has demonstrated that many ICU survivors can suffer from ill health and mental health issues for months or years to follow. The Textbook of Post-ICU Medicine: The Legacy of Critical Care identifies the long term outcomes of ICU and the steps that can be taken to improve patients' health and wellbeing. Describing the major clinical syndromes affecting ICU survivors, the book delineates established or postulated biological mechanisms of the post-acute recovery process, and discusses strategies for treatment and rehabilitation to promote recovery in the ICU and in the long term. The book serves as a unique reference for general practitioners, internists and nurses caring for long term ICU survivors as well as specialists in intensive care medicine, neurology, psychiatry, and rehabilitation medicine. |
define physiological dependence: Principles of Addiction , 2013-05-17 Principles of Addiction provides a solid understanding of the definitional and diagnostic differences between use, abuse, and disorder. It describes in great detail the characteristics of these syndromes and various etiological models. The book's three main sections examine the nature of addiction, including epidemiology, symptoms, and course; alcohol and drug use among adolescents and college students; and detailed descriptions of a wide variety of addictive behaviors and disorders, encompassing not only drugs and alcohol, but caffeine, food, gambling, exercise, sex, work, social networking, and many other areas. This volume is especially important in providing a basic introduction to the field as well as an in-depth review of our current understanding of the nature and process of addictive behaviors. Principles of Addiction is one of three volumes comprising the 2,500-page series, Comprehensive Addictive Behaviors and Disorders. This series provides the most complete collection of current knowledge on addictive behaviors and disorders to date. In short, it is the definitive reference work on addictions. - Each article provides glossary, full references, suggested readings, and a list of web resources - Edited and authored by the leaders in the field around the globe – the broadest, most expert coverage available - Encompasses types of addiction, as well as personality and environmental influences on addiction |
define physiological dependence: Psychological Treatment of Medical Patients Struggling with Harmful Substance Use Julie A. Schumacher, Daniel C. Williams, 2019-10-08 This book shows mental health providers how to assess and treat substance use in medical settings. Clinical health psychologists often encounter patients needing interventions for substance use, yet rarely do practitioners receive specialized training in this area. Psychological Treatment of Medical Patients With Harmful Substance Use is designed for mental health providers in medical settings who need the knowledge and skills to assess and treat conditions relevant to substance use. This book is especially useful for mental health providers who treat adult medical outpatients for whom substance use is not their primary presenting problem. The authors clarify the distinction between nonharmful and harmful substance use, describe the signs and symptoms of substance use disorders, epidemiology, current models denoting biological and socio-cultural causes, and contributing factors (with an emphasis on cardiac, cancer, women's health, and primary care settings). They offer best-practice assessment strategies, and psychological, self-help and pharmacological treatments. Chapters also describe assessment and intervention for conditions that are often comorbid with substance use, including depression, anxiety, and sleep dysregulation, as well as treatment for family members who are dealing with a loved one's harmful substance use, relapse prevention and continuing care. |
define physiological dependence: Theories on Drug Abuse National Institute on Drug Abuse. Division of Research, 1980 |
define physiological dependence: A Guide To Treatments that Work Peter Nathan, Jack M. Gorman, 2002-01-18 A fully revised and updated edition of this unique and authoritative reference The award-winning A Guide to Treatments that Work , published in 1998, was the first book to assemble the numerous advances in both clinical psychology and psychiatry into one accessible volume. It immediately established itself as an indispensable reference for all mental health practitioners. Now in a fully updated edition,A Guide to Treatments that Work, Second Edition brings together, once again, a distinguished group of psychiatrists and clinical psychologists to take stock of which treatments and interventions actually work, which don't, and what still remains beyond the scope of our current knowledge. The new edition has been extensively revised to take account of recent drug developments and advances in psychotherapeutic interventions. Incorporating a wealth of new information, these eminent researchers and clinicians thoroughly review all available outcome data and clinical trials and provide detailed specification of methods and procedures to ensure effective treatment for each major DSM-IV disorder. As an interdisciplinary work that integrates information from both clinical psychology and psychiatry, this new edition will continue to serve as an essential volume for practitioners of every kind: psychiatrists, psychologists, clinical social workers, counselors, and mental health consultants. |
define physiological dependence: Psychology of Substance Abuse André Luiz Monezi Andrade, Denise De Micheli, Eroy Aparecida da Silva, Fernanda Machado Lopes, Bruno de Oliveira Pinheiro, Richard Alecsander Reichert, 2021-04-15 This book is a guide for psychologists working with substance users in different healthcare settings, from private clinical practice to larger health institutions and community services. It presents a comprehensive overview of the different aspects involved with substance use disorders from a psychological perspective, from prevention to recovery. The volume offers an integrative view about neurobiological, behavioral and psychosocial aspects related to becoming a substance user; shows how psychological assessment tools can be used to diagnose substance use disorders; describes how different kinds of psychotherapy can be applied in the treatment of substance use disorders; and presents a range of evidence-based clinical and social interventions designed for both prevention and treatment of substance use disorders. Apart from covering the whole range of services related to the prevention, diagnosis and treatment of substance use disorders, the volume also shows how these issues can be approached from different theoretical perspectives within psychology, such as: Behavioral and Cognitive Psychology Neuropsychology Existential Psychology Phenomenology Psychoanalysis Analytical Psychology Community and Social Psychology Psychology of Substance Abuse: Psychotherapy, Clinical Management and Social Intervention will be a useful resource for psychologists and other health professionals working with substance users, as well as to undergraduate and graduate students looking for a comprehensive introduction to the psychology of substance abuse. |
define physiological dependence: Facing Addiction in America Office of the Surgeon General, U.s. Department of Health and Human Services, 2017-08-15 All across the United States, individuals, families, communities, and health care systems are struggling to cope with substance use, misuse, and substance use disorders. Substance misuse and substance use disorders have devastating effects, disrupt the future plans of too many young people, and all too often, end lives prematurely and tragically. Substance misuse is a major public health challenge and a priority for our nation to address. The effects of substance use are cumulative and costly for our society, placing burdens on workplaces, the health care system, families, states, and communities. The Report discusses opportunities to bring substance use disorder treatment and mainstream health care systems into alignment so that they can address a person's overall health, rather than a substance misuse or a physical health condition alone or in isolation. It also provides suggestions and recommendations for action that everyone-individuals, families, community leaders, law enforcement, health care professionals, policymakers, and researchers-can take to prevent substance misuse and reduce its consequences. |
define physiological dependence: Psychological Treatment for Patients with Chronic Pain Beth Darnall, 2018-08 Chronic pain is the most common long-term health condition in the United States. For the nearly 100 million Americans who struggle with this burden, the substantial risks of prescription opioid treatment have left many searching for safer, more effective alternatives. While multidisciplinary pain treatment programs can help, they are few in number--and few mental health practitioners receive adequate training in pain treatment. This book provides a comprehensive overview of treating patients with chronic pain, using evidence-based therapies. Taking a multidisciplinary approach that includes cognitive-behavioral therapy, acceptance and commitment therapy, and chronic pain self-management, Darnall shows mental health professionals how to utilize mindfulness interventions, hypnosis, and biofeedback, and also address comorbid problems such as depression, anxiety, and insomnia. Included are compelling case studies, and resources for clinical and patient training. |
define physiological dependence: Psychodynamics of Drug Dependence National Institute on Drug Abuse. Division of Research, 1977 |
define physiological dependence: Gambling Disorder Andreas Heinz, Nina Romanczuk-Seiferth, Marc N. Potenza, 2019-01-05 This book provides an overview of the state of the art in research on and treatment of gambling disorder. As a behavioral addiction, gambling disorder is of increasing relevance to the field of mental health. Research conducted in the last decade has yielded valuable new insights into the characteristics and etiology of gambling disorder, as well as effective treatment strategies. The different chapters of this book present detailed information on the general concept of addiction as applied to gambling, the clinical characteristics, epidemiology and comorbidities of gambling disorder, as well as typical cognitive distortions found in patients with gambling disorder. In addition, the book includes chapters discussing animal models and the genetic and neurobiological underpinnings of the disorder. Further, it is examining treatment options including pharmacological and psychological intervention methods, as well as innovative new treatment approaches. The book also discusses relevant similarities to and differences with substance-related disorders and other behavioral addictions. Lastly, it examines gambling behavior from a cultural perspective, considers possible prevention strategies and outlines future perspectives in the field. |
define physiological dependence: WHO Expert Committee on Drug Dependence World Health Organization, 2024-04-19 The Forty-sixth Meeting of the World Health Organisation (WHO)’s Expert Committee on Drug Dependence (ECDD) was convened from 16 to 19 October 2023 and was coordinated from the WHO headquarters in Geneva. The Forty-sixth WHO ECDD critically reviewed six new psychoactive substances: including two benzodiazepines (bromazolam, flubromazepam), one novel synthetic opioid (butonitazene), two cathinones/stimulants (3-CMC, dipentylone) and one dissociative-type substance (2-fluorodeschloroketamine). A critical review to consider international scheduling measures was undertaken for each substance so that the Expert Committee could consider whether information about these substances may justify the scheduling or a change in scheduling of a substance in the 1961 or 1971 Conventions. In addition, the Forty-sixth ECDD carried out a pre-review of nitrous oxide and carisoprodol to consider whether current information justified a critical review. This report summarizes the findings of the forty-sixth ECDD meeting. |
define physiological dependence: Mechanisms of Tolerance and Dependence , 1984 |
define physiological dependence: Theory and Practice of Addiction Counseling Pamela S. Lassiter, John R. Culbreth, 2017-02-17 Theory and Practice of Addiction Counseling by Pamela S. Lassiter and John R. Culbreth brings together contemporary theories of addiction and helps readers connect those theories to practice using a common multicultural case study. Theories covered include motivational interviewing, moral theory, developmental theory, cognitive behavioral theories, attachment theory, and sociological theory. Each chapter focuses on a single theory, describing its basic tenets, philosophical underpinnings, key concepts, and strengths and weaknesses. Each chapter also shows how practitioners using the theory would respond to a common case study, giving readers the opportunity to compare how the different theoretical approaches are applied to client situations. A final chapter discusses approaches to relapse prevention. |
define physiological dependence: Encyclopedia of Molecular Pharmacology Stefan Offermanns, W. Rosenthal, 2008-08-14 An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles. |
define physiological dependence: Pathways of Addiction Institute of Medicine, Committee on Opportunities in Drug Abuse Research, 1996-10-01 Drug abuse persists as one of the most costly and contentious problems on the nation's agenda. Pathways of Addiction meets the need for a clear and thoughtful national research agenda that will yield the greatest benefit from today's limited resources. The committee makes its recommendations within the public health framework and incorporates diverse fields of inquiry and a range of policy positions. It examines both the demand and supply aspects of drug abuse. Pathways of Addiction offers a fact-filled, highly readable examination of drug abuse issues in the United States, describing findings and outlining research needs in the areas of behavioral and neurobiological foundations of drug abuse. The book covers the epidemiology and etiology of drug abuse and discusses several of its most troubling health and social consequences, including HIV, violence, and harm to children. Pathways of Addiction looks at the efficacy of different prevention interventions and the many advances that have been made in treatment research in the past 20 years. The book also examines drug treatment in the criminal justice setting and the effectiveness of drug treatment under managed care. The committee advocates systematic study of the laws by which the nation attempts to control drug use and identifies the research questions most germane to public policy. Pathways of Addiction provides a strategic outline for wise investment of the nation's research resources in drug abuse. This comprehensive and accessible volume will have widespread relevanceâ€to policymakers, researchers, research administrators, foundation decisionmakers, healthcare professionals, faculty and students, and concerned individuals. |
define physiological dependence: Handbook of Pain Management Michael Serpell, 2011-10-22 Successful pain management is key to patient quality of life and outcomes across many fields of medicine. The Handbook of Pain Management provides an insightful and comprehensive summary, authored by a noted expert. Concise and insightful review of an important and complicated area of medicine |
define physiological dependence: The Promise of Adolescence National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division, Division of Behavioral and Social Sciences and Education, Board on Children, Youth, and Families, Committee on the Neurobiological and Socio-behavioral Science of Adolescent Development and Its Applications, 2019-07-26 Adolescenceâ€beginning with the onset of puberty and ending in the mid-20sâ€is a critical period of development during which key areas of the brain mature and develop. These changes in brain structure, function, and connectivity mark adolescence as a period of opportunity to discover new vistas, to form relationships with peers and adults, and to explore one's developing identity. It is also a period of resilience that can ameliorate childhood setbacks and set the stage for a thriving trajectory over the life course. Because adolescents comprise nearly one-fourth of the entire U.S. population, the nation needs policies and practices that will better leverage these developmental opportunities to harness the promise of adolescenceâ€rather than focusing myopically on containing its risks. This report examines the neurobiological and socio-behavioral science of adolescent development and outlines how this knowledge can be applied, both to promote adolescent well-being, resilience, and development, and to rectify structural barriers and inequalities in opportunity, enabling all adolescents to flourish. |
define physiological dependence: Adolescence and Emerging Adulthood Jeffrey Jensen Arnett, 2013 Helps students understand how culture impacts development in adolescence and emerging adulthood. Grounded in a global cultural perspective (within and outside of the US), this text enriches the discussion with historical context and an interdisciplinary approach, including studies from fields such as anthropology and sociology, in addition to the compelling psychological research on adolescent development. This book also takes into account the period of emerging adulthood (ages 18-25), a term coined by the author, and an area of study for which Arnett is a leading expert. Arnett continues the fifth edition with new and updated studies, both U.S. and international. With Pearson's MyDevelopmentLab Video Series and Powerpoints embedded with video, students can experience a true cross-cultural experience. A better teaching and learning experience This program will provide a better teaching and learning experience-- for you and your students. Here's how: Personalize Learning - The new MyDevelopmentLab delivers proven results in helping students succeed, provides engaging experiences that personalize learning, and comes from a trusted partner with educational expertise and a deep commitment to helping students and instructors achieve their goals. Improve Critical Thinking - Students learn to think critically about the influence of culture on development with pedagogical features such as Culture Focus boxes and Historical Focus boxes. Engage Students - Arnett engages students with cross cultural research and examples throughout. MyVirtualTeen, an interactive simulation, allows students to apply the concepts they are learning to their own virtual teen. Explore Research - Research Focus provides students with a firm grasp of various research methods and helps them see the impact that methods can have on research findings. Support Instructors - This program provides instructors with unbeatable resources, including video embedded PowerPoints and the new MyDevelopmentLab that includes cross-cultural videos and MyVirtualTeen, an interactive simulation that allows you to raise a child from birth to age 18. An easy to use Instructor's Manual, a robust test bank, and an online test generator (MyTest) are also available. All of these materials may be packaged with the text upon request. Note: MyDevelopmentLab does not come automatically packaged with this text. To purchase MyDevelopmentLab, please visit: www.mydevelopmentlab.com or you can purchase a ValuePack of the text + MyDevelopmentlab (at no additional cost): ValuePack ISBN-10: 0205911854/ ValuePack ISBN-13: 9780205911851. Click here for a short walkthrough video on MyVirtualTeen! http://www.youtube.com/playlist'list=PL51B144F17A36FF25&feature=plcp |
define physiological dependence: TIP 35: Enhancing Motivation for Change in Substance Use Disorder Treatment (Updated 2019) U.S. Department of Health and Human Services, 2019-11-19 Motivation is key to substance use behavior change. Counselors can support clients' movement toward positive changes in their substance use by identifying and enhancing motivation that already exists. Motivational approaches are based on the principles of person-centered counseling. Counselors' use of empathy, not authority and power, is key to enhancing clients' motivation to change. Clients are experts in their own recovery from SUDs. Counselors should engage them in collaborative partnerships. Ambivalence about change is normal. Resistance to change is an expression of ambivalence about change, not a client trait or characteristic. Confrontational approaches increase client resistance and discord in the counseling relationship. Motivational approaches explore ambivalence in a nonjudgmental and compassionate way. |
define physiological dependence: Pharmacology and Therapeutics Scott A. Waldman, Andre Terzic, 2009 Everything you need to know about all of today's drugs in a coherent, easy-to-use format - from the underlying science through innovation, translation, regulation, and clinical implementation. This multimedia resource fills a critical need for a more clinically focused, user-friendly pharmacology reference. Evidence-based therapeutic guidelines facilitate decision making; and coverage of pharmacogenetics and pharmacogenomics, regenerative pharmacology, stem cell therapies, and the emerging field of individualized medicine keeps you at the forefront of the latest developments. |
define physiological dependence: Treating and Preventing Adolescent Mental Health Disorders Dwight L. Evans, Daniel Romer, 2017 This volume reviews the latest information about the treatment and prevention of major mental disorders that emerge during adolescence. It should be a primary resource for both clinicians and researchers, with special attention to gaps in our knowledge. |
define physiological dependence: WHO Report on the Global Tobacco Epidemic 2019 World Health Organization, 2020-01-10 The report Offering help to quit tobacco use tracks the status of the tobacco epidemic and interventions to combat it. The report finds that more countries have implemented tobacco control policies, ranging from graphic pack warnings and advertising bans to no smoking areas. About 5 billion people - 65% of the world's population - are covered by at least one comprehensive tobacco control measure, which has more than quadrupled since 2007 when only 1 billion people and 15% of the world's population were covered. |
define physiological dependence: Testing Drugs for Physical Dependence Potential and Abuse Liability Committee on Problems of Drug Dependence (U.S.), 1984 |
define physiological dependence: The Secret Disease of Addiction Jane Allen, 2009-11-22 Addiction starts and ends in the brain. In this extraordinary book, discover scientific truths about this disease of stress that creates a real biological need for relief. Written in clear matter-of fact text supported by simple illustrations and stunning graphics, Jane Allen's understanding and knowledge come through these pages with an empathy that can only arise from personal experience. Whether trapped in the prison of addiction or caught up in the ripple effect, this information goes right to the source of this problem. This book offers help for those directly or indirectly affected, and offers astonishing insights into the chronic relapse condition of disinformation and denial. |
define physiological dependence: Introduction to Addiction George F. Koob, Michael A. Arends, Mandy L McCracken, Michel Lemoal, 2019-06-12 Introduction to Addiction, Volume One in the series, introduces the reader to the study of neurobiology of addiction by clearly defining addiction and its neuroadaptational views. This volume includes thorough descriptions of the various animal models applicable to the study of addiction, including Animal Models of the Binge-Intoxication Stage of the Addiction Cycle and Animal Models of Vulnerability to Addiction. The book's authors also include a section on numerous neurobiological theories that aid in the understanding of addiction, including dopamine, prefrontal cortex and relapse. |
define physiological dependence: Animal Models of Drug Addiction Mary C. Olmstead, 2010-12-10 Our understanding of addiction and how it is treated has advanced remarkably over the past decades, and much of the progress is related directly to animal research. This is true for both the behavioural aspects of drug use as well as the biological underpinnings of the disorder. In Animal Models of Drug Addiction, experts in the field provide an up-to-date review of complex behavioural paradigms that model different stages of this disorder and explain how each test is used to effectively replicate the progression of drug addiction. This detailed and practical book begins with the most common laboratory measures of addiction in animals, including intracranial self-stimulation (ICSS), drug self-administration, place conditioning, and sensitization. Later chapters describe how these paradigms are used to model the progression of drug addiction, providing insight into the clinical symptomatology of addiction from acquisition of drug use through compulsive drug taking to withdrawal and relapse. Written for the popular Neuromethods series, the contributions offer both methodological detail and a theoretical perspective, appealing to readers familiar with preclinical research on drug addiction as well as those who are newcomers to the field. Cutting-edge and authoritative, Animal Models of Drug Addiction will serve as a basis for future vital research that links the bench to the bedside in the crucial treatment of drug addiction. |
define physiological dependence: Lexicon of Alcohol and Drug Terms World Health Organization, 1994 Provides user with definitions of terms concerned with aspects of alcohol, tobacco, and other drug use. Definitions generally deal with psychoactive effects of substances, symptomology, sequelae, and therapeutic indications. |
define physiological dependence: International Handbook of Alcohol Dependence and Problems Nick Heather, Timothy J. Peters, Tim Stockwell, 2001-05-18 Focusing on alcohol dependence and alcohol-related problems in general, as well as their causes, treatment and prevention, this handbook also addresses the basic mechanisms of alcohol and its effects on human physiology and behaviour. |
define physiological dependence: Webster's New World Dictionary of the American Language David Bernard Guralnik, 1977 |
define physiological dependence: Trauma and Substance Abuse Paige Ouimette, Pamela J. Brown, 2003 Trauma and Substance Abuse explores the underrecognized connection between trauma, substance use, and posttraumatic stress disorder (PTSD). Patients with trauma related distress such as PTSD often have comorbid substance use disorders (SUDs). This book presents cutting-edge research on how often the two disorders co-occur and why. Authors describe models of comorbidity and explore how specific PTSD and substance use symptoms are functionally related to each other. In addition, they suggest assessment approaches and practice guidelines to facilitate proper diagnosis and treatment. Particularly valuable are descriptions of several new treatment approaches that have been developed specifically for PTSD-SUD, including cognitive-behavioral and exposure therapy. This is the first book to evaluate and synthesize the two fields of PTSD and substance use disorder research and treatment. This volume is indispensable for researchers and clinicians seeking a full understanding of the etiology, assessment, and treatment of this challenging dual diagnosis. |
define physiological dependence: Psychological Drug Research Jorge Negreiros, 2006 |
define physiological dependence: Drug Misuse and Dependence Clinical Guidelines on Drug Misuse and Dependence Update 2017 Independent Expert Working Group, 2017 |
DEFINE Definition & Meaning - Merriam-Webster
The meaning of DEFINE is to determine or identify the essential qualities or meaning of. How to use define in a sentence.
DEFINE Definition & Meaning | Dictionary.com
Define definition: to state or set forth the meaning of (a word, phrase, etc.).. See examples of DEFINE used in a sentence.
DEFINE | English meaning - Cambridge Dictionary
DEFINE definition: 1. to say what the meaning of something, especially a word, is: 2. to explain and describe the…. Learn more.
DEFINE definition and meaning | Collins English Dictionary
If you define something, you show, describe, or state clearly what it is and what its limits are, or what it is like. We were unable to define what exactly was wrong with him. [ VERB wh ]
Define - definition of define by The Free Dictionary
define - show the form or outline of; "The tree was clearly defined by the light"; "The camera could define the smallest object"
DEFINE - Definition & Meaning - Reverso English Dictionary
Define definition: state the meaning of a word or phrase. Check meanings, examples, usage tips, pronunciation, domains, related words.
define - Wiktionary, the free dictionary
May 13, 2025 · define (third-person singular simple present defines, present participle defining, simple past and past participle defined) To determine with precision; to mark out with …
Define: Definition, Meaning, and Examples - usdictionary.com
Dec 24, 2024 · The word "define" means to explain or clarify the meaning of something or to establish boundaries and parameters. It is a versatile word used in many contexts, from …
Define Definition & Meaning - YourDictionary
Define Sentence Examples The child's eagerness and interest carry her over many obstacles that would be our undoing if we stopped to define and explain everything. It will not be welfare (or, …
DEFINITION Definition & Meaning - Merriam-Webster
The meaning of DEFINITION is a statement of the meaning of a word or word group or a sign or symbol. How to use definition in a sentence.
DEFINE Definition & Meaning - Merriam-Webster
The meaning of DEFINE is to determine or identify the essential qualities or meaning of. How to use define in a sentence.
DEFINE Definition & Meaning | Dictionary.com
Define definition: to state or set forth the meaning of (a word, phrase, etc.).. See examples of DEFINE used in a sentence.
DEFINE | English meaning - Cambridge Dictionary
DEFINE definition: 1. to say what the meaning of something, especially a word, is: 2. to explain and describe the…. Learn more.
DEFINE definition and meaning | Collins English Dictionary
If you define something, you show, describe, or state clearly what it is and what its limits are, or what it is like. We were unable to define what exactly was wrong with him. [ VERB wh ]
Define - definition of define by The Free Dictionary
define - show the form or outline of; "The tree was clearly defined by the light"; "The camera could define the smallest object"
DEFINE - Definition & Meaning - Reverso English Dictionary
Define definition: state the meaning of a word or phrase. Check meanings, examples, usage tips, pronunciation, domains, related words.
define - Wiktionary, the free dictionary
May 13, 2025 · define (third-person singular simple present defines, present participle defining, simple past and past participle defined) To determine with precision; to mark out with …
Define: Definition, Meaning, and Examples - usdictionary.com
Dec 24, 2024 · The word "define" means to explain or clarify the meaning of something or to establish boundaries and parameters. It is a versatile word used in many contexts, from …
Define Definition & Meaning - YourDictionary
Define Sentence Examples The child's eagerness and interest carry her over many obstacles that would be our undoing if we stopped to define and explain everything. It will not be welfare (or, …
DEFINITION Definition & Meaning - Merriam-Webster
The meaning of DEFINITION is a statement of the meaning of a word or word group or a sign or symbol. How to use definition in a sentence.