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define dominance in biology: Experiments in Plant-hybridisation Gregor Mendel, 1925 |
define dominance in biology: Principles of Biology Lisa Bartee, Walter Shiner, Catherine Creech, 2017 The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research. |
define dominance in biology: Brenner's Encyclopedia of Genetics Stanley Maloy, Kelly Hughes, 2013-03-03 The explosion of the field of genetics over the last decade, with the new technologies that have stimulated research, suggests that a new sort of reference work is needed to keep pace with such a fast-moving and interdisciplinary field. Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set, builds on the foundation of the first edition by addressing many of the key subfields of genetics that were just in their infancy when the first edition was published. The currency and accessibility of this foundational content will be unrivalled, making this work useful for scientists and non-scientists alike. Featuring relatively short entries on genetics topics written by experts in that topic, Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set provides an effective way to quickly learn about any aspect of genetics, from Abortive Transduction to Zygotes. Adding to its utility, the work provides short entries that briefly define key terms, and a guide to additional reading and relevant websites for further study. Many of the entries include figures to explain difficult concepts. Key terms in related areas such as biochemistry, cell, and molecular biology are also included, and there are entries that describe historical figures in genetics, providing insights into their careers and discoveries. This 7-volume set represents a 25% expansion from the first edition, with over 1600 articles encompassing this burgeoning field Thoroughly up-to-date, with many new topics and subfields covered that were in their infancy or not inexistence at the time of the first edition. Timely coverage of emergent areas such as epigenetics, personalized genomic medicine, pharmacogenetics, and genetic enhancement technologies Interdisciplinary and global in its outlook, as befits the field of genetics Brief articles, written by experts in the field, which not only discuss, define, and explain key elements of the field, but also provide definition of key terms, suggestions for further reading, and biographical sketches of the key people in the history of genetics |
define dominance in biology: Social Dominance Jim Sidanius, Felicia Pratto, 2001-02-12 This volume focuses on two questions: why do people from one social group oppress and discriminate against people from other groups? and why is this oppression so mind numbingly difficult to eliminate? The answers to these questions are framed using the conceptual framework of social dominance theory. Social dominance theory argues that the major forms of intergroup conflict, such as racism, classism and patriarchy, are all basically derived from the basic human predisposition to form and maintain hierarchical and group-based systems of social organization. In essence, social dominance theory presumes that, beneath major and sometimes profound difference between different human societies, there is also a basic grammar of social power shared by all societies in common. We use social dominance theory in an attempt to identify the elements of this grammar and to understand how these elements interact and reinforce each other to produce and maintain group-based social hierarchy. |
define dominance in biology: Mendel's Principles of Heredity William Bateson, Gregor Mendel, 1902 Bateson named the science genetics in 1905-1906. This is the first textbook in English on the subject of genetics. |
define dominance in biology: Dominance and Aggression in Humans and Other Animals Henry R. Hermann, 2017-01-05 Dominance and Aggression in Humans and Other Animals: The Great Game of Life examines human nature and the influence of evolution, genetics, chemistry, nurture, and the sociopolitical environment as a way of understanding how and why humans behave in aggressive and dominant ways. The book walks us through aggression in other social species, compares and contrasts human behavior to other animals, and then explores specific human behaviors like bullying, abuse, territoriality murder, and war. The book examines both individual and group aggression in different environments including work, school, and the home. It explores common stressors triggering aggressive behaviors, and how individual personalities can be vulnerable to, or resistant to, these stressors. The book closes with an exploration of the cumulative impact of human aggression and dominance on the natural world. - Reviews the influence of evolution, genetics, biochemistry, and nurture on aggression - Explores aggression in multiple species, including insects, fish, reptiles, birds, and mammals - Compares human and animal aggressive and dominant behavior - Examines bullying, abuse, territoriality, murder, and war - Includes nonaggressive behavior in displays of respect and tolerance - Highlights aggression triggers from drugs to stress - Discusses individual and group behavior, including organizations and nations - Probes dominance and aggression in religion and politics - Translates the impact of human behavior over time on the natural world |
define dominance in biology: Encyclopedia of Genetics Sydney Brenner, Jeffrey H. Miller, William J. Broughton, 2002 The Encyclopedia of Genetics provides the most complete and authoritative coverage of genetics ever published. Dr. Sydney Brenner, the 2002 Nobel Prize winner for Physiology or Medicine, and Professor Jeffrey H. Miller of UCLA have gathered the world's top geneticists to contribute to this outstanding collection. Diverse information is compiled into a single, comprehensive source, containing a clear presentation of cutting-edge knowledge. Easy-to-use and well-organized, the Encyclopedia of Genetics is an invaluable reference work for everyone from the academic researcher to the educated layperson. The Encyclopedia provides: * Comprehensive coverage: at 4 volumes and over 1,700 entries this is the largest Genetics reference work currently available * Complete, up-to-date information * Initial online access to the online version, which includes fully searchable text and numerous hyperlinks to related sites * Cross-references to related articles within the Encyclopedia * 2800 pages; two-color printing throughout text and figures; color plate sections also included.--Provided by publisher |
define dominance in biology: Exploring the Biological Contributions to Human Health Institute of Medicine, Board on Health Sciences Policy, Committee on Understanding the Biology of Sex and Gender Differences, 2001-07-02 It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers. |
define dominance in biology: A History of Genetics Alfred Henry Sturtevant, 2001 In the small “Fly Room†at Columbia University, T.H. Morgan and his students, A.H. Sturtevant, C.B. Bridges, and H.J. Muller, carried out the work that laid the foundations of modern, chromosomal genetics. The excitement of those times, when the whole field of genetics was being created, is captured in this book, written in 1965 by one of those present at the beginning. His account is one of the few authoritative, analytic works on the early history of genetics. This attractive reprint is accompanied by a website, http://www.esp.org/books/sturt/history/ offering full-text versions of the key papers discussed in the book, including the world's first genetic map. |
define dominance in biology: Animal Weapons Douglas J. Emlen, 2014-11-11 Emlen takes us outside the lab and deep into the forests and jungles where he's been studying animal weapons in nature for years, to explain the processes behind the most intriguing and curious examples of extreme animal weapons. As singular and strange as some of the weapons we encounter on these pages are, we learn that similar factors set their evolution in motion. Emlen uses these patterns to draw parallels to the way we humans develop and employ our own weapons, and have since battle began. |
define dominance in biology: Concepts of Biology Samantha Fowler, Rebecca Roush, James Wise, 2023-05-12 Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy. |
define dominance in biology: Genetic Instabilities and Neurological Diseases Robert D. Wells, Tetsuo Ashizawa, 2011-10-13 Genetic Instabilities and Neurological Diseases covers DNA repeat instability and neurological disorders, covering molecular mechanisms of repeat expansion, pathogenic mechanisms, clinical phenotype, parental gender effects, genotype-phenotype correlation, and diagnostic applications of the molecular data. This updated edition provides updates of these repeat expansion mutations, including the addition of many new chapters, and old chapters rewritten as extensions of the previous edition. This book is an invaluable reference source for neuroscientists, geneticists, neurologists, molecular biologists, genetic counsellors and students. - Contributions by most of the principal research teams in the area, edited by world-renowned leaders - Lays the background for future investigations on related diseases |
define dominance in biology: Language Dominance in Bilinguals Jeanine Treffers-Daller, Carmen Silva-Corvalán, 2016 With contributions from an international team of leading experts, this volume offers new ways to explore and measure language dominance. |
define dominance in biology: Insect Resistance Management David W. Onstad, 2013-10-08 Neither pest management nor resistance management can occur with only an understanding of pest biology. For years, entomologists have understood, with their use of economic thresholds, that at least a minimal use of economics was necessary for proper integrated pest management. IRM is even more complicated and dependent on understanding and using socioeconomic factors. The new edition of Insect Resistance Management addresses these issues and much more. Many new ideas, facts and case studies have been developed since the previous edition of Insect Resistance Management published. With a new chapter focusing on Resistance Mechanisms Related to Plant-incorporated Toxins and heavily expanded revisions of several existing chapters, this new volume will be an invaluable resource for IRM researchers, practitioners, professors and advanced students. Authors in this edition include professors at major universities, leaders in the chemical and seed industry, evolutionary biologists and active IRM practitioners. This revision also contains more information about IRM outside North America, and a modeling chapter contains a large new section on uncertainty analysis, a subject recently emphasized by the U.S. Environmental Protection Agency. The final chapter contains a section on insecticidal seed treatments. No other book has the breadth of coverage of Insect Resistance Management, 2e. It not only covers molecular to economic issues, but also transgenic crops, seed treatments and other pest management tactics such as crop rotation. Major themes continuing from the first edition include the importance of using IRM in the integrated pest management paradigm, the need to study and account for pest behavior, and the influence of human behavior and decision making in IRM. - Provides insights from the history of insect resistance management (IRM) to the latest science - Includes contributions from experts on ecological aspects of IRM, molecular and population genetics, economics, and IRM social issues - Offers biochemistry and molecular genetics of insecticides presented with an emphasis on recent research - Encourages scientists and stakeholders to implement and coordinate strategies based on local social conditions |
define dominance in biology: The Fourth Industrial Revolution Klaus Schwab, 2017-01-03 World-renowned economist Klaus Schwab, Founder and Executive Chairman of the World Economic Forum, explains that we have an opportunity to shape the fourth industrial revolution, which will fundamentally alter how we live and work. Schwab argues that this revolution is different in scale, scope and complexity from any that have come before. Characterized by a range of new technologies that are fusing the physical, digital and biological worlds, the developments are affecting all disciplines, economies, industries and governments, and even challenging ideas about what it means to be human. Artificial intelligence is already all around us, from supercomputers, drones and virtual assistants to 3D printing, DNA sequencing, smart thermostats, wearable sensors and microchips smaller than a grain of sand. But this is just the beginning: nanomaterials 200 times stronger than steel and a million times thinner than a strand of hair and the first transplant of a 3D printed liver are already in development. Imagine “smart factories” in which global systems of manufacturing are coordinated virtually, or implantable mobile phones made of biosynthetic materials. The fourth industrial revolution, says Schwab, is more significant, and its ramifications more profound, than in any prior period of human history. He outlines the key technologies driving this revolution and discusses the major impacts expected on government, business, civil society and individuals. Schwab also offers bold ideas on how to harness these changes and shape a better future—one in which technology empowers people rather than replaces them; progress serves society rather than disrupts it; and in which innovators respect moral and ethical boundaries rather than cross them. We all have the opportunity to contribute to developing new frameworks that advance progress. |
define dominance in biology: Comprehensive and Molecular Phytopathology Yuri Dyakov, Vitaly Dzhavakhiya, Timo Korpela, 2007-01-09 This book offers a collection of information on successive steps of molecular 'dialogue' between plants and pathogens. It additionally presents data that reflects intrinsic logic of plant-parasite interactions. New findings discussed include: host and non-host resistance, specific and nonspecific elicitors, elicitors and suppressors, and plant and animal immunity. This book enables the reader to understand how to promote or prevent disease development, and allows them to systematize their own ideas of plant-pathogen interactions.* Offers a more extensive scope of the problem as compared to other books in the market* Presents data to allow consideration of host-parasite relationships in dynamics and reveals interrelations between pathogenicity and resistance factors* Discusses beneficial plant-microbe interactions and practical aspects of molecular investigations of plant-parasite relationships* Compares historical study of common and specific features of plant immunity with animal immunity |
define dominance in biology: Janeway's Immunobiology Kenneth Murphy, Paul Travers, Mark Walport, Peter Walter, 2010-06-22 The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes. |
define dominance in biology: Molecular Biology of the Cell , 2002 |
define dominance in biology: Safety of Genetically Engineered Foods National Research Council, Institute of Medicine, Board on Agriculture and Natural Resources, Food and Nutrition Board, Board on Life Sciences, Committee on Identifying and Assessing Unintended Effects of Genetically Engineered Foods on Human Health, 2004-07-08 Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre- and post-market approaches to guide the assessment of unintended compositional changes that could result from genetically modified foods and research avenues to fill the knowledge gaps. |
define dominance in biology: Scientific Frontiers in Developmental Toxicology and Risk Assessment National Research Council, Commission on Life Sciences, Board on Environmental Studies and Toxicology, Committee on Developmental Toxicology, 2000-12-21 Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians. |
define dominance in biology: Conceptual Breakthroughs in Evolutionary Genetics John C. Avise, 2014-01-18 Conceptual Breakthroughs in Evolutionary Genetics is a pithy, lively book occupying a special niche—the conceptual history of evolutionary genetics— not inhabited by any other available treatment. Written by a world-leading authority in evolutionary genetics, this work encapsulates and ranks 70 of the most significant paradigm shifts in evolutionary biology and genetics during the century-and-a-half since Darwin and Mendel. The science of evolutionary genetics is central to all of biology, but many students and other practitioners have little knowledge of its historical roots and conceptual developments. This book fills that knowledge gap in a thought-provoking and readable format. This fascinating chronological journey along the many conceptual pathways to our modern understanding of evolutionary and genetic principles is a wonderful springboard for discussions in undergraduate or graduate seminars in evolutionary biology and genetics. But more than that, anyone interested in the history and philosophy of science will find much of value between its covers. - Provides a relative ranking of 70 seminal breakthroughs and paradigm shifts in the field of evolutionary biology and genetics - Modular format permits ready access to each described subject - Historical overview of a field whose concepts are central to all of biology and relevant to a broad audience of biologists, science historians, and philosophers of science - Extensively cross-referenced with a guide to landmark papers and books for each topic |
define dominance in biology: The Germ-plasm August Weismann, 1893 |
define dominance in biology: Endless Forms Most Beautiful Sean B. Carroll, 2005 As described in this fascinating book, Evo Devo is evolutionary development biology, the third revolution in the science, which shows how the endless forms of animals--butterflies and zebras, trilobites and dinosaurs, apes and humans--were made and evolved. |
define dominance in biology: Genes, Culture, and Personality Bozzano G Luisa, 2014-04-25 The diversity of human behavior is one of the most fascinating aspects of human biology. What makes our individual attitudes, lifestyle and personalities different has been the subject of many physiological and psychological theories. In this book the emphasis is on understanding the genetic and environmental causes of these differences. Genes, Culture, and Personality is an expansive account of the state of current knowledge about the causes of individual differences in personality and social attitudes. Based on almost two decades of empirical research, the authors have made a significant contribution to the debate on genetic and cultural inheritance in human behavior. The book should be required reading for psychologists, psychiatrists, sociobiologists, and geneticists. |
define dominance in biology: Stable Isotopes and Plant Carbon-Water Relations , 2012-12-02 This 33-chapter volume presents a critical examination of the importance of stable isotopes in understanding key plant metabolic processes. - Carbon isotope analyses for estimates of plant water use and metabolism - Integrated estimates of stress impacts and life history in ecological systems - Hydrogen and oxygen isotope analyses for evaluating water sources and transpiration - Use of stable isotopes in scaling from leaf to global levels - Sections include: History and Theoretical Considerations, Ecological Aspects of Carbon Isotope Variation, Agricultural Aspects of Carbon Isotope Variation, Genetics and Isotopic Variation, Water Relations and Isotopic Composition |
define dominance in biology: Health Effects of Exposure to Low Levels of Ionizing Radiation National Research Council, Division on Earth and Life Studies, Commission on Life Sciences, Committee on the Biological Effects of Ionizing Radiation (BEIR V), 1990-02-01 This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations. |
define dominance in biology: Models of Biological Pattern Formation Hans Meinhardt, 1982 |
define dominance in biology: Induced Fish Breeding Nihar Ranjan Chattopadhyay, 2016-10-19 Induced Fish Breeding: A Practical Guide for Hatcheries takes a successive approach to explaining the use of breeding technology with proven scientific methods. It provides real-life examples for the purpose of maximizing fish and seed production to support overall sustainability in aquaculture. It is a concise reference to understanding the latest developments in the field, useful for anyone who is involved in fisheries or hatchery management as well as researchers and students who need to understand the technology. A practice originally developed to produce quality seed in captivity, induced breeding has made great strides in fish populations for India. The book offers a practical and succinct overview—from existing methods and operations to recent trends and their impacts on aquaculture for the future. - Provides detailed information about empirical breeding practices like mixed spawning and indiscriminate hybridization - Presents the environmental and hormonal influence on maturation and spawning of fish with real-life fish breeding examples from around the world - Includes step-by-step scientific measures to help solve problems arising from common fish-farming mistakes - Provides real-life examples for the purpose of maximizing fish and seed production to support overall sustainability in aquaculture |
define dominance in biology: Genetics Daniel L. Hartl, Elizabeth W. Jones, 1998 |
define dominance in biology: A Dictionary of Genetics Robert C. King, 1972 700 new words added to reflect recent advances in the field. Appendixes include historical chronology; a list of periodicals; laboratories engaged in studies of human genetics in Canada, Mexico, and the United States; and teaching aids. 1st ed., 1968. |
define dominance in biology: The Biology of the Laboratory Rabbit Steven H. Weisbroth, Ronald E. Flatt, Alan L. Kraus, 2013-10-02 The Biology of the Laboratory Rabbit is a compendium of papers that discusses the use of the rabbit as an experimental substrate in the scientific process. The collection describes normative biology, research utilization, and rabbit disease. These papers emphasize naturally occurring diseases which affect the value of the rabbit as a research tool. Some papers describe these effects and their impact for investigators engaged in laboratory experimental work on animal medicine. Other papers tackle the value of certain rabbit diseases as models of considerable interest in comparative medicine. Several papers discuss bacterial diseases, viral diseases, protozoal diseases, arthropod parasites, helminth parasites, neoplastic diseases, inherited diseases, nutritional diseases, metabolic, traumatic, mycotic, and miscellaneous diseases of the rabbit. One paper describes a number of diseases that man can acquire from domestic and laboratory rabbits. These include tularemia (which is endemic in wild rabbits and hares), plague (transmitted by fleas), listeriosis (rare in laboratory rabbit colonies), salmonellosis (from rabbit feces), and Pasteurella multocida (common in laboratory and domestic rabbits). The paper notes that laboratory and domestic rabbits are not a major health hazard. The compendium can benefit veterinarians, the medically-oriented investigator, the biologist, the medical and chemical researcher, and others whose work involve laboratory animal care. |
define dominance in biology: Statistical Human Genetics Robert C. Elston, Jaya M. Satagopan, Shuying Sun, 2012-02-04 Recent advances in genetics over the last quarter of a century, especially in molecular techniques, have dramatically reduced the cost of determining genetic markers and hence opened up a field of research that is increasingly helping to detect, prevent and/or cure many diseases that afflict humans. In Statistical Human Genetics: Methods and Protocols expert researchers in the field describe statistical methods and computer programs in the detail necessary to make them more easily accessible to the beginner analyzing data. Written in the highly successful Methods in Molecular BiologyTM series format, with examples of running the programs and interpreting the program outputs, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results from human genetic data collected in the laboratory. Thorough and as much as possible intuitive, Statistical Human Genetics: Methods and Protocols aids scientists in understanding the computer programs and analytical procedures they need to use. |
define dominance in biology: The Promise of Adolescence National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division, Division of Behavioral and Social Sciences and Education, Board on Children, Youth, and Families, Committee on the Neurobiological and Socio-behavioral Science of Adolescent Development and Its Applications, 2019-07-26 Adolescenceâ€beginning with the onset of puberty and ending in the mid-20sâ€is a critical period of development during which key areas of the brain mature and develop. These changes in brain structure, function, and connectivity mark adolescence as a period of opportunity to discover new vistas, to form relationships with peers and adults, and to explore one's developing identity. It is also a period of resilience that can ameliorate childhood setbacks and set the stage for a thriving trajectory over the life course. Because adolescents comprise nearly one-fourth of the entire U.S. population, the nation needs policies and practices that will better leverage these developmental opportunities to harness the promise of adolescenceâ€rather than focusing myopically on containing its risks. This report examines the neurobiological and socio-behavioral science of adolescent development and outlines how this knowledge can be applied, both to promote adolescent well-being, resilience, and development, and to rectify structural barriers and inequalities in opportunity, enabling all adolescents to flourish. |
define dominance in biology: The Physical Basis of Heredity Thomas Hunt Morgan, 1919 |
define dominance in biology: The Neuroscience of Emotion Ralph Adolphs, David J. Anderson, 2018-06-05 A new framework for the neuroscientific study of emotions in humans and animals The Neuroscience of Emotion presents a new framework for the neuroscientific study of emotion across species. Written by Ralph Adolphs and David J. Anderson, two leading authorities on the study of emotion, this accessible and original book recasts the discipline and demonstrates that in order to understand emotion, we need to examine its biological roots in humans and animals. Only through a comparative approach that encompasses work at the molecular, cellular, systems, and cognitive levels will we be able to comprehend what emotions do, how they evolved, how the brain shapes their development, and even how we might engineer them into robots in the future. Showing that emotions are ubiquitous across species and implemented in specific brain circuits, Adolphs and Anderson offer a broad foundation for thinking about emotions as evolved, functionally defined biological states. The authors discuss the techniques and findings from modern neuroscientific investigations of emotion and conclude with a survey of theories and future research directions. Featuring color illustrations throughout, The Neuroscience of Emotion synthesizes the latest in neuroscientific work to provide deeper insights into how emotions function in all of us. |
define dominance in biology: Handbook of Pharmacogenomics and Stratified Medicine Sandosh Padmanabhan, 2014-04-28 Handbook of Pharmacogenomics and Stratified Medicine is a comprehensive resource to understand this rapidly advancing field aiming to deliver the right drug at the right dose to the right patient at the right time. It is designed to provide a detailed, but accessible review of the entire field from basic principles to applications in various diseases. The chapters are written by international experts to allow readers from a wide variety of backgrounds, clinical and non-clinical (basic geneticists, pharmacologists, clinicians, trialists, industry personnel, ethicists) to understand the principles underpinning the progress in this area, the successes, failures and the challenges ahead. To be accessible to the widest range of readers, the clinical application section introduces the disease process, existing therapies, followed by pharmacogenomics and stratified medicine details.Medicine is the cornerstone of modern therapeutics prescribed on the basis that its benefit should outweigh its risk. It is well known that people respond differently to medications and in many cases the risk-benefit ratio for a particular drug may be a gray area. The last decade has seen a revolution in genomics both in terms of technological innovation and discovering genetic markers associated with disease. In parallel there has been steady progress in trying to make medicines safer and tailored to the individual. This has occurred across the whole spectrum of medicine, some more than others. In addition there is burgeoning interest from the pharmaceutical industry to leverage pharmacogenomics for more effective and efficient clinical drug development. - Provides clinical and non-clinical researchers with practical information normally beyond their usual areas of research or expertise - Includes an basic principles section explaining concepts of basic genetics, genetic epidemiology, bioinformatics, pharmacokinetics and pharmacodynamics - Covers newer technologies– next generation sequencing, proteomics, metabolomics - Provides information on animal models, lymphoblastoid cell lines, stem cells - Provides detailed chapters on a wide range of disease conditions, implementation and regulatory issues - Includes chapters on the global implications of pharmacogenomics |
define dominance in biology: The Great Mental Models, Volume 1 Shane Parrish, Rhiannon Beaubien, 2024-10-15 Discover the essential thinking tools you’ve been missing with The Great Mental Models series by Shane Parrish, New York Times bestselling author and the mind behind the acclaimed Farnam Street blog and “The Knowledge Project” podcast. This first book in the series is your guide to learning the crucial thinking tools nobody ever taught you. Time and time again, great thinkers such as Charlie Munger and Warren Buffett have credited their success to mental models–representations of how something works that can scale onto other fields. Mastering a small number of mental models enables you to rapidly grasp new information, identify patterns others miss, and avoid the common mistakes that hold people back. The Great Mental Models: Volume 1, General Thinking Concepts shows you how making a few tiny changes in the way you think can deliver big results. Drawing on examples from history, business, art, and science, this book details nine of the most versatile, all-purpose mental models you can use right away to improve your decision making and productivity. This book will teach you how to: Avoid blind spots when looking at problems. Find non-obvious solutions. Anticipate and achieve desired outcomes. Play to your strengths, avoid your weaknesses, … and more. The Great Mental Models series demystifies once elusive concepts and illuminates rich knowledge that traditional education overlooks. This series is the most comprehensive and accessible guide on using mental models to better understand our world, solve problems, and gain an advantage. |
define dominance in biology: The Genetical Theory of Natural Selection R. A. Fisher, 2018-11-10 This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. |
define dominance in biology: Twin and Family Studies of Epigenetics Shuai Li, John Hopper, 2021-08-19 Twin and Family Studies of Epigenetics, Volume 27, the latest release in the Translational Epigenetics series, gathers expert opinions on epigenetic twin and family study research methods, recent findings across various disease areas, and future directions. The book provides in-depth coverage of epigenetics fundamentals, twin and family epigenetic study design, and the broader role of epigenetics in answering questions on the developmental origins of health and disease. Throughout the volume, twin and family studies are employed to examine causes of epigenetic variation, the relationship between epigenetic modifications and mental illness, cancers, cardiovascular disease, diabetes, obesity, high blood pressure, and more. Emerging research methods applied in twin and family studies discussed include imaging epigenetics, exposure-specific DNA methylation changes, and unravelling time trends in epigenetic effects. - Offers a practical, interdisciplinary approach across epigenetics, epidemiology and various disease specialties - Applies epigenetic twin and family studies to determine the relationship between epigenetics and mental illness, cancers, cardiovascular disease, diabetes, obesity and high blood pressure, among other diseases and disorders - Features chapter contributions from a wide range of international researchers in the field |
define dominance in biology: Darwinian Dynamics Richard E. Michod, 2021-01-12 The concept of fitness has long been a topic of intense debate among evolutionary biologists and their critics, with its definition and explanatory power coming under attack. In this book, Richard Michod offers a fresh, dynamical interpretation of evolution and fitness concepts. He argues that evolution has no enduring products; what matters is the process of genetic change. Whereas many biologists have focused on competition and aggression as determining factors in survival, Michod, by concentrating on the emergence of individuality at new and more complex levels, finds that cooperation plays even a greater role. Michod first considers the principles behind the hierarchically nested levels of organization that constitute life: genes, chromosomes, genomes, cells, multicellular organisms, and societies. By examining the evolutionary transitions from the molecular level up to the whole organism, the author explains how cooperation and conflict in a multilevel setting leads to new levels of fitness. He builds a model of fitness drawing on recent developments in ecology and multilevel selection theory and on new explanations of the origin of life. Michod concludes with a discussion of the philosophical implications of his theory of fitness, a theory that addresses the most fundamental and unique concept in all of biology. |
DEFINE Definition & Meaning - Merriam-Webster
The meaning of DEFINE is to determine or identify the essential qualities or meaning of. How to use define in a sentence.
DEFINE Definition & Meaning | Dictionary.com
Define definition: to state or set forth the meaning of (a word, phrase, etc.).. See examples of DEFINE used in a …
DEFINE | English meaning - Cambridge Dictionary
DEFINE definition: 1. to say what the meaning of something, especially a word, is: 2. to explain and describe …
DEFINE definition and meaning | Collins English Di…
If you define something, you show, describe, or state clearly what it is and what its limits are, or what it is like. We were unable to define what exactly was wrong with him. [ VERB wh ]
Define - definition of define by The Free Dictionary
define - show the form or outline of; "The tree was clearly defined by the light"; "The camera could define the smallest object"
DEFINE Definition & Meaning - Merriam-Webster
The meaning of DEFINE is to determine or identify the essential qualities or meaning of. How to use define in a sentence.
DEFINE Definition & Meaning | Dictionary.com
Define definition: to state or set forth the meaning of (a word, phrase, etc.).. See examples of DEFINE used in a sentence.
DEFINE | English meaning - Cambridge Dictionary
DEFINE definition: 1. to say what the meaning of something, especially a word, is: 2. to explain and describe the…. Learn more.
DEFINE definition and meaning | Collins English Dictionary
If you define something, you show, describe, or state clearly what it is and what its limits are, or what it is like. We were unable to define what exactly was wrong with him. [ VERB wh ]
Define - definition of define by The Free Dictionary
define - show the form or outline of; "The tree was clearly defined by the light"; "The camera could define the smallest object"
DEFINE - Definition & Meaning - Reverso English Dictionary
Define definition: state the meaning of a word or phrase. Check meanings, examples, usage tips, pronunciation, domains, related words.
define - Wiktionary, the free dictionary
May 13, 2025 · define (third-person singular simple present defines, present participle defining, simple past and past participle defined) To determine with precision; to mark out with …
Define: Definition, Meaning, and Examples - usdictionary.com
Dec 24, 2024 · The word "define" means to explain or clarify the meaning of something or to establish boundaries and parameters. It is a versatile word used in many contexts, from …
Define Definition & Meaning - YourDictionary
Define Sentence Examples The child's eagerness and interest carry her over many obstacles that would be our undoing if we stopped to define and explain everything. It will not be welfare (or, …
DEFINITION Definition & Meaning - Merriam-Webster
The meaning of DEFINITION is a statement of the meaning of a word or word group or a sign or symbol. How to use definition in a sentence.